05:02:2021 13:48 mouse_stages_ontology 1.2 fbb definition term replaced by Count of number of days intervening between the end of the stage and the time of birth according to a reference model. Note that the first day of post-birth development has the value of 1 for this property, and the period during which the child is one day old has the value 2 mouse_stages_ontology end_dpb true This is a shortcut annotation that can be expanded to an OWL axiom, or to a set of OWL axioms. The exact translation has yet to be determined, and may be application-dependent. end, days post birth Count of number of days intervening between the end of the stage and the time of coitum, assuming that it takes place around midnight during a 7pm to 5am dark cycle (noon of the day on which the vaginal plug is found, the embryos are aged 0.5 days post coitum). mouse_stages_ontology end_dpc true This is a shortcut annotation that can be expanded to an OWL axiom, or to a set of OWL axioms. The exact translation has yet to be determined, and may be application-dependent. end, days post coitum Count of number of days intervening between the end of the stage and the time of coitum, assuming that it takes place around midnight during a 7pm to 5am dark cycle (noon of the day on which the vaginal plug is found, the embryos are aged 0.5 days post coitum). http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Timed_Pregnancy Count of number of months intervening between the end of the stage and the time of birth according to a reference model. Note that the first month of post-birth development has the value of 1 for this property, and the period during which the mouse is one month old has the value 2 mouse_stages_ontology end_mpb true This is a shortcut annotation that can be expanded to an OWL axiom, or to a set of OWL axioms. The exact translation has yet to be determined, and may be application-dependent. end, months post birth Count of number of weeks intervening between the end of the stage and the time of birth according to a reference model. Note that the first week of post-birth development has the value of 1 for this property, and the period during which the mouse is one week old has the value 2 mouse_stages_ontology end_wpb true This is a shortcut annotation that can be expanded to an OWL axiom, or to a set of OWL axioms. The exact translation has yet to be determined, and may be application-dependent. end, weeks post birth Subset consisting of classes describing highly granular developmental stages (for instance, '23-year-old'). Such stages might be useful for annotation purpose, but might be folded into less granular parents for display purpose. mouse_stages_ontology has_end_time true has end time mouse_stages_ontology has_start_time true has start time mouse_stages_ontology has_unit true Used to associate a measurement property (e.g. days post fertilization) with a unit (e.g. days) has unit Count of number of days intervening between the start of the stage and the time of birth according to a reference model. Note that the first day of post-birth development has the value of 0 for this property, and the period during which the child is one day old has the value 1. mouse_stages_ontology start_dpb true This is a shortcut annotation that can be expanded to an OWL axiom, or to a set of OWL axioms. The exact translation has yet to be determined, and may be application-dependent. start, days post birth Count of number of days intervening between the start of the stage and the time of coitum, assuming that it takes place around midnight during a 7pm to 5am dark cycle (noon of the day on which the vaginal plug is found, the embryos are aged 0.5 days post coitum). mouse_stages_ontology start_dpc true This is a shortcut annotation that can be expanded to an OWL axiom, or to a set of OWL axioms. The exact translation has yet to be determined, and may be application-dependent. start, days post coitum Count of number of days intervening between the start of the stage and the time of coitum, assuming that it takes place around midnight during a 7pm to 5am dark cycle (noon of the day on which the vaginal plug is found, the embryos are aged 0.5 days post coitum). http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Timed_Pregnancy Count of number of days intervening between the start of the stage and the time of fertilization according to a reference model. Note that the first day of development has the value of 0 for this property. mouse_stages_ontology start_dpf true This is a shortcut annotation that can be expanded to an OWL axiom, or to a set of OWL axioms. The exact translation has yet to be determined, and may be application-dependent. start, days post fertilization Count of number of months intervening between the start of the stage and the time of birth according to a reference model. Note that the first month of post-birth development has the value of 0 for this property, and the period during which the mouse is one month old has the value 1. mouse_stages_ontology start_mpb true This is a shortcut annotation that can be expanded to an OWL axiom, or to a set of OWL axioms. The exact translation has yet to be determined, and may be application-dependent. start, months post birth Count of number of weeks intervening between the start of the stage and the time of birth according to a reference model. Note that the first week of post-birth development has the value of 0 for this property, and the period during which the mouse is one week old has the value 1. mouse_stages_ontology start_wpb true This is a shortcut annotation that can be expanded to an OWL axiom, or to a set of OWL axioms. The exact translation has yet to be determined, and may be application-dependent. start, weeks post birth subset_property consider database_cross_reference has_exact_synonym has_narrow_synonym has_obo_format_version has_obo_namespace has_related_synonym in_subset shorthand BFO:0000050 mouse_stages_ontology part_of part_of part of X preceded_by Y iff: end(Y) before_or_simultaneous_with start(X) BFO:0000062 mouse_stages_ontology preceded_by preceded_by preceded_by X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y) RO:0002087 mouse_stages_ontology immediately_preceded_by immediately_preceded_by immediately_preceded_by A spatiotemporal region encompassing some part of the life cycle of an organism. UBERON:0000105 developmental stage stage mouse_stages_ontology MmusDv:0000000 life cycle stage A spatiotemporal region encompassing some part of the life cycle of an organism. UBERON:0000105 Temporal interval that defines mouse life from prenatal stage until late adult stage. 0.45 UBERON:0000104 mouse_developmental_stage MmusDv:0000001 life cycle Temporal interval that defines mouse life from prenatal stage until late adult stage. Bgee:curator Prenatal stage that starts with fertilization and ends with a fully formed embryo, before undergoing last development during the fetal stage. 0.45 0.0 mouse_developmental_stage MmusDv:0000002 By embryo we mean in the sense of up to the 2nd week postfertilization (beginning of Theiler stage 23), we treat fetus as a separate stage. embryonic stage Prenatal stage that starts with fertilization and ends with a fully formed embryo, before undergoing last development during the fetal stage. Bgee:curator Embryonic stage defined by a one-cell embryo (fertilised egg) with zona pellucida present. 0.45 EMAPA:TS01 UBERON:0000106 XUO:0000045 E0-2.5 Theiler stage 1 mouse_developmental_stage TS01 (E0-2.5) zygote stage MmusDv:0000003 "Starts the mouse development sequence, range from embryonic age 0-0.9 dpc (day post coitum). Assumes that fertilization takes place around midnight during a 7pm to 5am dark cycle. Noon of the day on which the vaginal plug is found the embryos are aged 0.5 d.p.c (days post coitum)." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Timed_Pregnancy "adapted from"] Theiler stage 01 Embryonic stage defined by a one-cell embryo (fertilised egg) with zona pellucida present. http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_1 TS01 (E0-2.5) EMAPA:TS01 Embryonic stage consisting of division of cells in the early embryo. UBERON:0000107 mouse_developmental_stage MmusDv:0000004 The different cells derived from cleavage are called blastomeres and form a compact mass called the morula. Cleavage ends with the formation of the blastula. cleavage stage Embryonic stage consisting of division of cells in the early embryo. UBERON:0000107 Embryonic cleavage stage defined by a dividing 2-4 cells egg. 1.0 EMAPA:TS02 XUO:0000046 E1-2.5 TS02 Theiler stage 2 mouse_developmental_stage TS02 (E1-2.5) MmusDv:0000005 Embryonic age 1 dpc (day post coitum). Theiler stage 02 Embryonic cleavage stage defined by a dividing 2-4 cells egg. http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_2 TS02 (E1-2.5) EMAPA:TS02 Embryonic cleavage stage defined by a dividing 4-16 cells egg, early to fully compacted morula. 2.0 EMAPA:TS03 XUO:0000047 E1-3.5 TS03 Theiler stage 3 mouse_developmental_stage TS03 (E1-3.5) MmusDv:0000006 Embryonic age 2 dpc (day post coitum). Theiler stage 03 Embryonic cleavage stage defined by a dividing 4-16 cells egg, early to fully compacted morula. http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_3 TS03 (E1-3.5) EMAPA:TS03 Embryonic stage that is an early stage of embryonic development in animals and is produced by cleavage of a fertilized ovum, with formation of a central fluid-filled cavity called the blastocoel. UBERON:0000108 mouse_developmental_stage MmusDv:0000007 The blastula follows the morula and precedes the gastrula in the developmental sequence. blastula stage Embryonic stage that is an early stage of embryonic development in animals and is produced by cleavage of a fertilized ovum, with formation of a central fluid-filled cavity called the blastocoel. UBERON:0000108 Embryonic blastula stage defined by a dividing 16-40 cells egg, with early evidence of the blastocoelic cavity. 3.0 EMAPA:TS04 XUO:0000048 E2-4 TS04 Theiler stage 4 mouse_developmental_stage TS04 (E2-4) MmusDv:0000008 Embryonic age 3 dpc (day post coitum). Theiler stage 04 Embryonic blastula stage defined by a dividing 16-40 cells egg, with early evidence of the blastocoelic cavity. http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_4 TS04 (E2-4) EMAPA:TS04 Embryonic blastula stage defined by a zona free blastocyst (zona pellucida absent). 4.0 EMAPA:TS05 XUO:0000049 E3-5.5 TS05 Theiler stage 5 mouse_developmental_stage TS05 (E3-5.5) MmusDv:0000009 Embryonic age 4 dpc (day post coitum). Theiler stage 05 Embryonic blastula stage defined by a zona free blastocyst (zona pellucida absent). http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_5 TS05 (E3-5.5) EMAPA:TS05 Embryonic blastula stage during which the blastocyst attaches, with first evidence of embryonic endoderm cells covering the blastocoelic surface of the inner cell mass. 4.5 EMAPA:TS06 XUO:0000050 E4-5.5 TS06 Theiler stage 6 mouse_developmental_stage TS06 (E4-5.5) MmusDv:0000010 Embryonic age 4.5 dpc (day post coitum). Refers to human CarnegieStage04. Theiler stage 06 Embryonic blastula stage during which the blastocyst attaches, with first evidence of embryonic endoderm cells covering the blastocoelic surface of the inner cell mass. http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_6 TS06 (E4-5.5) EMAPA:TS06 Embryonic blastula stage defined by implantation and formation of the egg cylinder resulting from the rapid increase in the number of inner cell mass cells. 5.0 EMAPA:TS07 XUO:0000051 E4.5-6 TS07 Theiler stage 7 mouse_developmental_stage TS07 (E4.5-6) MmusDv:0000011 Embryonic age 5 dpc (day post coitum). Refers to human CarnegieStage05. Theiler stage 07 Embryonic blastula stage defined by implantation and formation of the egg cylinder resulting from the rapid increase in the number of inner cell mass cells. http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_7 TS07 (E4.5-6) EMAPA:TS07 Embryonic blastula stage during which the egg cylinder differentiates into embryonic and extra-embryonic regions, and the pro-amniotic cavity appears. 6.0 EMAPA:TS08 XUO:0000052 E5-6.5 TS08 Theiler stage 8 mouse_developmental_stage TS08 (E5-6.5) MmusDv:0000012 Embryonic age 6 dpc (day post coitum). Refers to human CarnegieStage05. Theiler stage 08 Embryonic blastula stage during which the egg cylinder differentiates into embryonic and extra-embryonic regions, and the pro-amniotic cavity appears. http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_8 TS08 (E5-6.5) EMAPA:TS08 Embryonic stage defined by complex and coordinated series of cellular movements that occurs at the end of cleavage. UBERON:0000109 mouse_developmental_stage MmusDv:0000013 gastrula stage Embryonic stage defined by complex and coordinated series of cellular movements that occurs at the end of cleavage. UBERON:0000109 Embryonic gastrula stage during which gastrulation starts with first evidence of mesoderm and visible embryonic axis. 6.5 EMAPA:TS09 XUO:0000053 E6.25-7.25 TS09 Theiler stage 9 mouse_developmental_stage TS09 (E6.25-7.25) MmusDv:0000014 Embryonic age 6.5 dpc (day post coitum). Theiler stage 09 Embryonic gastrula stage during which gastrulation starts with first evidence of mesoderm and visible embryonic axis. http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_9 TS09 (E6.25-7.25) EMAPA:TS09 Embryonic gastrula stage during which the primitive streak bulges into the pro-amniotic cavity and forms the amniotic fold; the exocoelom appears; the allantoic bud first appears, gastrulation continues and the node becomes visible. 7.0 EMAPA:TS10 XUO:0000054 E6.5-7.75 TS10 mouse_developmental_stage TS10 (E6.5-7.75) MmusDv:0000015 Embryonic age 7 dpc (day post coitum), (range 6.5-7.5 dpc). Refers to human CarnegieStage08. Theiler stage 10 Embryonic gastrula stage during which the primitive streak bulges into the pro-amniotic cavity and forms the amniotic fold; the exocoelom appears; the allantoic bud first appears, gastrulation continues and the node becomes visible. http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_10 TS10 (E6.5-7.75) EMAPA:TS10 Embryonic stage defined by formation of a tube from the flat layer of ectodermal cells known as the neural plate. MmusDv:0000017 mouse_developmental_stage TheilerStage11 MmusDv:0000016 This term was obsoleted as it was the only child associated to MmusDv:0000017., This stage starts the emergence of the central nervous system at embryonic age 7.5 dpc (day post coitum). neurula stage true Embryonic stage defined by formation of a tube from the flat layer of ectodermal cells known as the neural plate. UBERON:0000110 Embryonic stage called presomite stage and defined by the formation of the neural plate. 7.5 EMAPA:TS11 UBERON:0000110 XUO:0000055 E7.25-8 TS11 mouse_developmental_stage TS11 (E7.25-8) neurula stage MmusDv:0000017 This stage starts the emergence of the central nervous system at embryonic age 7.5 dpc (day post coitum). Theiler stage 11 Embryonic stage called presomite stage and defined by the formation of the neural plate. http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_11 TS11 (E7.25-8) EMAPA:TS11 Embryonic stage at which the ectoderm, endoderm, and mesoderm develop into the internal organs of the organism. UBERON:0000111 mouse_developmental_stage MmusDv:0000018 organogenesis stage Embryonic stage at which the ectoderm, endoderm, and mesoderm develop into the internal organs of the organism. UBERON:0000111 Organogenesis stage during which first somites become visible. 8.0 EMAPA:TS12 XUO:0000056 E7.5-8.75 TS12 mouse_developmental_stage TS12 (E7.5-8.75) MmusDv:0000019 Embryonic age 8 dpc (day post coitum). Refers to human CarnegieStage09. Theiler stage 12 Organogenesis stage during which first somites become visible. http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_12 TS12 (E7.5-8.75) EMAPA:TS12 Organogenesis stage defined by the turning of the embryo; initiated in embryos with 6-8 pairs of somites and usually completed in embryos with 14-16 pairs of somites. 8.5 EMAPA:TS13 XUO:0000057 E8-9.25 TS13 mouse_developmental_stage TS13 (E8-9.25) MmusDv:0000020 Embryonic age 8.5 dpc (day post coitum). Refers to human CarnegieStage10. Theiler stage 13 Organogenesis stage defined by the turning of the embryo; initiated in embryos with 6-8 pairs of somites and usually completed in embryos with 14-16 pairs of somites. http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_13 TS13 (E8-9.25) EMAPA:TS13 Organogenesis stage during which the rostral extremity of the neural tube closes in embryos with usually about 15-18 somite pairs. Late in the stage the 3rd branchial arch becomes visible. 9.0 EMAPA:TS14 XUO:0000058 E8.5-9.75 TS14 mouse_developmental_stage TS14 (E8.5-9.75) MmusDv:0000021 Embryonic age 9 dpc (day post coitum). Refers to human CarnegieStage11. Theiler stage 14 Organogenesis stage during which the rostral extremity of the neural tube closes in embryos with usually about 15-18 somite pairs. Late in the stage the 3rd branchial arch becomes visible. http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_14 TS14 (E8.5-9.75) EMAPA:TS14 Organogenesis stage during which the posterior neuropore forms and the condensation of the forelimb bud becomes apparent near the 8th-12th somite pairs. 9.5 EMAPA:TS15 XUO:0000059 E9-10.25 TS15 mouse_developmental_stage TS15 (E9-10.25) MmusDv:0000022 Embryonic age 9.5 dpc (day post coitum). Refers to human CarnegieStage12. Theiler stage 15 Organogenesis stage during which the posterior neuropore forms and the condensation of the forelimb bud becomes apparent near the 8th-12th somite pairs. http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_15 TS15 (E9-10.25) EMAPA:TS15 Organogenesis stage during which the posterior neuropore closes and the hind limb bud becomes visible at the level of the 23rd-28th somites. 10.0 EMAPA:TS16 XUO:0000060 E9.5-10.75 TS16 mouse_developmental_stage TS16 (E9.5-10.75) MmusDv:0000023 Embryonic age 10 dpc (day post coitum). Refers to human CarnegieStages 13 to 15. Theiler stage 16 Organogenesis stage during which the posterior neuropore closes and the hind limb bud becomes visible at the level of the 23rd-28th somites. http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_16 TS16 (E9.5-10.75) EMAPA:TS16 Organogenesis stage defined by the deepening of the lens pit and the first appearance of the physiological umbilical hernia. 10.5 EMAPA:TS17 XUO:0000061 E10-11.25 TS17 mouse_developmental_stage TS17 (E10-11.25) MmusDv:0000024 Embryonic age 10.5 dpc (day post coitum). Refers to human CarnegieStages 13 to 15. Theiler stage 17 Organogenesis stage defined by the deepening of the lens pit and the first appearance of the physiological umbilical hernia. http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_17 TS17 (E10-11.25) EMAPA:TS17 Organogenesis stage during which the lens vesicle gradually closes and the nasal pits start to form. The rapid growth of the brain is striking. 11.0 EMAPA:TS18 XUO:0000062 E10.5-11.25 TS18 mouse_developmental_stage TS18 (E10.5-11.25) MmusDv:0000025 Embryonic age 11 dpc (day post coitum). Refers to human CarnegieStages 13 to 15. Theiler stage 18 Organogenesis stage during which the lens vesicle gradually closes and the nasal pits start to form. The rapid growth of the brain is striking. http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_18 TS18 (E10.5-11.25) EMAPA:TS18 Organogenesis stage during which the lens vesicle becomes completely closed and detached from the ectoderm, and peripheral margins of the eye become well defined. 11.5 EMAPA:TS19 XUO:0000063 E11-12.25 TS19 mouse_developmental_stage TS19 (E11-12.25) MmusDv:0000026 Embryonic age 11.5 dpc (day post coitum). Refers to human CarnegieStage16. Theiler stage 19 Organogenesis stage during which the lens vesicle becomes completely closed and detached from the ectoderm, and peripheral margins of the eye become well defined. http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_19 TS19 (E11-12.25) EMAPA:TS19 Organogenesis stage during which the handplate develops angles corresponding to the future digits, and tongue and brain vesicles are clearly visible. 12.0 EMAPA:TS20 XUO:0000064 E11.5-13 TS20 mouse_developmental_stage TS20 (E11.5-13) MmusDv:0000027 Embryonic age 12 dpc (day post coitum). Refers to human CarnegieStage17. Theiler stage 20 Organogenesis stage during which the handplate develops angles corresponding to the future digits, and tongue and brain vesicles are clearly visible. http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_20 TS20 (E11.5-13) EMAPA:TS20 Organogenesis stage during which the digit widths and locations can be discerned, and the pinna rapidly develops and forms a crest at right angles to the head. 13.0 EMAPA:TS21 XUO:0000065 E12.5-14 TS21 mouse_developmental_stage TS21 (E12.5-14) MmusDv:0000028 Embryonic age 13 dpc (day post coitum). Refers to human CarnegieStages 18 and 19. Theiler stage 21 Organogenesis stage during which the digit widths and locations can be discerned, and the pinna rapidly develops and forms a crest at right angles to the head. http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_21 TS21 (E12.5-14) EMAPA:TS21 Organogenesis stage during which the fingers are clearly visible and the long bones of the limbs are present. 14.0 EMAPA:TS22 XUO:0000066 E13.5-15 TS22 mouse_developmental_stage TS22 (E13.5-15) MmusDv:0000029 Embryonic age 14 dpc (day post coitum). Refers to human CarnegieStages 20 to 23. Theiler stage 22 Organogenesis stage during which the fingers are clearly visible and the long bones of the limbs are present. http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_22 TS22 (E13.5-15) EMAPA:TS22 life cycle that follows the embryonic development stage and during which further organogenesis and histogenesis occur. mouse_developmental_stage MmusDv:0000030 This term was obsoleted to follow human developmental ontology structure. post-embryonic developmental stage true life cycle that follows the embryonic development stage and during which further organogenesis and histogenesis occur. Bgee:curator Prenatal stage that starts with the fully formed embryo and ends at birth. UBERON:0007220 mouse_developmental_stage MmusDv:0000031 This stage describes the four Theiler stages that are commonly reported as equivalent to the human fetal period in the literature. They are anyway defined by embryonic days. fetal stage Prenatal stage that starts with the fully formed embryo and ends at birth. Bgee:curator Fetal stage during which the toes separate and hair follicles are present in the cephalic region but not at the periphery of the vibrissae. 15.0 EMAPA:TS23 XUO:0000067 E15 TS23 mouse_developmental_stage TS23 (E15) MmusDv:0000032 Embryonic age 15 dpc (day post coitum). Refers to the human fetal period. Theiler stage 23 Fetal stage during which the toes separate and hair follicles are present in the cephalic region but not at the periphery of the vibrissae. http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_23 TS23 (E15) EMAPA:TS23 Fetal stage during which the umbilical hernia disappears and there is a corresponding increase in the size of the peritoneal sac. 16.0 EMAPA:TS24 XUO:0000068 E16 TS24 mouse_developmental_stage TS24 (E16) MmusDv:0000033 Embryonic age 16 dpc (day post coitum). Refers to the human fetal period. Theiler stage 24 Fetal stage during which the umbilical hernia disappears and there is a corresponding increase in the size of the peritoneal sac. http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_24 TS24 (E16) EMAPA:TS24 Fetal stage during which the thickened skin forms wrinkles and the subcutaneous veins are less visible. 17.0 EMAPA:TS25 XUO:0000069 E17 TS25 mouse_developmental_stage TS25 (E17) MmusDv:0000034 Embryonic age 17 dpc (day post coitum). Refers to the human fetal period. Refers to rat Standard Witschi Stage 34 (see http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_25). Theiler stage 25 Fetal stage during which the thickened skin forms wrinkles and the subcutaneous veins are less visible. http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_25 TS25 (E17) EMAPA:TS25 Fetal stage defined by long whiskers and during which the eyes are barely visible through the closed eyelids. 0.0 18.0 EMAPA:TS26 XUO:0000070 E18 TS26 mouse_developmental_stage TS26 (E18) MmusDv:0000035 TS26 is used for the period from embryonic day 18 up to birth itself. [https://github.com/tfhayamizu]. Refers to rat Standard Witschi Stage 35 (see http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_26). Theiler stage 26 Fetal stage defined by long whiskers and during which the eyes are barely visible through the closed eyelids. http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_26 TS26 (E18) EMAPA:TS26 Stage that refers to the newborn mouse, aged E19-20, P0. Description of anatomical structures related to this stage corresponds to the first days of the mouse life. Used for postnatal days 0 through 3. 4.0 0.6 0.0 19.0 0.0 EMAPA:TS27 UBERON:0007221 XUO:0000071 newborn stage mouse_developmental_stage P0 TS27 MmusDv:0000036 TS27 is used for annotation of postnatal days 0 through 3 (P0 to P3). This is a somewhat arbitrary cut-off but seems to best fit the data we have encountered. TS28 is then used from postnatal day 4 onward. [https://github.com/tfhayamizu] Theiler stage 27 Stage that refers to the newborn mouse, aged E19-20, P0. Description of anatomical structures related to this stage corresponds to the first days of the mouse life. Used for postnatal days 0 through 3. https://github.com/tfhayamizu newborn stage UBERON:cjm P0 UBERON:cjm TS27 EMAPA:TS27 Development stage that defines the postnatal period, all the way through adulthood. 0.6 mouse_developmental_stage MmusDv:0000037 TS27 is used for annotation of postnatal days 0 through 3 (P0 to P3). This is a somewhat arbitrary cut-off but seems to best fit the data we have encountered. TS28 is then used from postnatal day 4 onward. [https://github.com/tfhayamizu] Theiler stage 28 true Development stage that defines the postnatal period, all the way through adulthood. https://github.com/tfhayamizu Immature stage that refers to a mouse which is over 1 week and under 6 weeks old. 6.0 1.0 MmusDv:0000140 MmusDv:0000141 MmusDv:0000142 MmusDv:0000143 MmusDv:0000144 MmusDv:0000145 MmusDv:0000146 MmusDv:0000147 MmusDv:0000148 MmusDv:0000149 MmusDv:0000150 1-5 weeks mouse_developmental_stage MmusDv:0000038 This term was made obsolete due to discussion at https://github.com/obophenotype/developmental-stage-ontologies/issues/23. [ANiknejad] infant stage true Immature stage that refers to a mouse which is over 1 week and under 6 weeks old. Bgee:curator Immature stage that refers to a mouse which is over 4 weeks and under 7 weeks old. 4-6 weeks mouse_developmental_stage MmusDv:0000039 This term was obsoleted as it is not fully accepted as a defined developmental stage in the literature. This stage describes the age at which mice are usually used as adolescent mouse models in the literature. adolescent stage true Immature stage that refers to a mouse which is over 4 weeks and under 7 weeks old. Bgee:curator Mouse developmental stage that refers to a mouse which is over 5 weeks old. MmusDv:0000110 mature mouse_developmental_stage MmusDv:0000040 This term was obsoleted to include the mature stage into the ontology. Both terms have the same children, but contains of children (children of children) differ. The organisation of the postnatal development time in mouse is debatable, literature usually refers to mature or immature mice, with milestone around 6-8 weeks post-natal. adult stage true Mouse developmental stage that refers to a mouse which is over 5 weeks old. Bgee:curator mouse_developmental_stage MmusDv:0000041 unknown true Mouse life cycle that starts with fertilization and ends with birth. 19.0 0.0 0.45 0.0 UBERON:0000068 mouse_developmental_stage MmusDv:0000042 prenatal stage Mouse life cycle that starts with fertilization and ends with birth. UBERON:0000068 Mouse developmental stage that covers the period from birth until 5 weeks old. 6.0 0.0 EMAPA:TS28 UBERON:0000112 mouse_developmental_stage MmusDv:0000043 It is commonly accepted that mouse reaches sexual maturity by six weeks of age (see http://www.ahc.umn.edu/rar/breeding.html). immature stage Mouse developmental stage that covers the period from birth until 5 weeks old. Bgee:curator Early immature stage that refers to the newborn mouse which is over 1 and under 8 days old. 1.143 0.143 MmusDv:0000036 MmusDv:0000139 mouse_developmental_stage MmusDv:0000044 This term was made obsolete due to discussion at https://github.com/obophenotype/developmental-stage-ontologies/issues/23. [ANiknejad] 1-7 days true Early immature stage that refers to the newborn mouse which is over 1 and under 8 days old. Bgee:curator Premature stage that refers to a mouse which is over 7 days and under 15 days old. 2.0 1.0 MmusDv:0000140 mouse_developmental_stage MmusDv:0000045 1 week true Premature stage that refers to a mouse which is over 7 days and under 15 days old. Bgee:curator Premature stage that refers to a mouse which is over 14 days and under 22 days old. 3.0 2.0 MmusDv:0000141 mouse_developmental_stage MmusDv:0000046 2 weeks true Premature stage that refers to a mouse which is over 14 days and under 22 days old. Bgee:curator Premature stage that refers to a mouse which is over 21 days and under 29 days old. 4.0 3.0 MmusDv:0000142 MmusDv:0000143 MmusDv:0000144 MmusDv:0000145 MmusDv:0000146 MmusDv:0000147 MmusDv:0000148 mouse_developmental_stage MmusDv:0000047 3-week-old stage true Premature stage that refers to a mouse which is over 21 days and under 29 days old. Bgee:curator Premature stage that refers to a mouse which is over 28 days and under 36 days old. 5.0 4.0 MmusDv:0000149 mouse_developmental_stage MmusDv:0000048 4 weeks true Premature stage that refers to a mouse which is over 28 days and under 36 days old. Bgee:curator Premature stage that refers to a mouse which is over 35 days and under 43 days old. 6.0 5.0 MmusDv:0000150 mouse_developmental_stage MmusDv:0000049 This stage is usually the stage during which the sexual maturity occurs. 5 weeks true Premature stage that refers to a mouse which is over 35 days and under 43 days old. Bgee:curator Early stage that refers to a mouse which is over 42 days and under 50 days old. 7.0 6.0 MmusDv:0000151 mouse_developmental_stage MmusDv:0000050 This stage is commonly considered in the literature as the milestone that distinguishes between sexually immmature and mature stages (see http://www.ahc.umn.edu/rar/breeding.html). 6 weeks true Early stage that refers to a mouse which is over 42 days and under 50 days old. Bgee:curator Early adult stage that refers to a mouse which is over 49 days and under 57 days old. 8.0 7.0 MmusDv:0000152 mouse_developmental_stage MmusDv:0000051 7 weeks true Early adult stage that refers to a mouse which is over 49 days and under 57 days old. Bgee:curator 2 month-old stage that refers to a mouse which is over 56 days and under 64 days old. 9.0 8.0 MmusDv:0000154 mouse_developmental_stage MmusDv:0000052 8 weeks true 2 month-old stage that refers to a mouse which is over 56 days and under 64 days old. Bgee:curator 2 month-old stage that refers to a mouse which is over 63 days and under 71 days old. 10.0 9.0 MmusDv:0000155 mouse_developmental_stage MmusDv:0000053 9 weeks true 2 month-old stage that refers to a mouse which is over 63 days and under 71 days old. Bgee:curator 2 month-old stage that refers to a mouse which is over 70 days and under 78 days old. 11.0 10.0 MmusDv:0000156 mouse_developmental_stage MmusDv:0000054 10 weeks true 2 month-old stage that refers to a mouse which is over 70 days and under 78 days old. Bgee:curator 2 month-old stage that refers to a mouse which is over 77 days and under 85 days old. 12.0 11.0 MmusDv:0000157 mouse_developmental_stage MmusDv:0000055 11 weeks true 2 month-old stage that refers to a mouse which is over 77 days and under 85 days old. Bgee:curator 3 month-old stage that refers to a mouse which is over 84 days and under 92 days old. 13.0 12.0 MmusDv:0000158 mouse_developmental_stage MmusDv:0000056 12 weeks true 3 month-old stage that refers to a mouse which is over 84 days and under 92 days old. Bgee:curator 3 month-old stage that refers to a mouse which is over 91 days and under 99 days old. 14.0 13.0 MmusDv:0000159 mouse_developmental_stage MmusDv:0000057 13 weeks true 3 month-old stage that refers to a mouse which is over 91 days and under 99 days old. Bgee:curator 3 month-old stage that refers to a mouse which is over 98 days and under 106 days old. 15.0 14.0 MmusDv:0000160 mouse_developmental_stage MmusDv:0000058 14 weeks true 3 month-old stage that refers to a mouse which is over 98 days and under 106 days old. Bgee:curator 3 month-old stage that refers to a mouse which is over 105 days and under 113 days old. 16.0 15.0 MmusDv:0000161 mouse_developmental_stage MmusDv:0000059 15 weeks true 3 month-old stage that refers to a mouse which is over 105 days and under 113 days old. Bgee:curator Mature stage that refers to a adult mouse which is over 6 weeks and under 7 months old. 7.0 30.0 1.5 6.0 MmusDv:0000136 UBERON:0018241 mouse_developmental_stage MmusDv:0000061 Mice under 7 months of age are commonly considered as young adult in the literature, without loss of functional capability like hearing (see http://www.ncbi.nlm.nih.gov/pubmed/18259074). early adult stage true Mature stage that refers to a adult mouse which is over 6 weeks and under 7 months old. http://research.jax.org/faculty/harrison/ger1vLifespan1.html#VD Early adult stage that refers to a mouse which is over 2 and under 3 months old. 3.0 12.0 2.0 8.0 mouse_developmental_stage MmusDv:0000062 2-month-old stage Early adult stage that refers to a mouse which is over 2 and under 3 months old. Bgee:curator Early adult stage that refers to a mouse which is over 3 and under 4 months old. 4.0 16.0 3.0 12.0 mouse_developmental_stage MmusDv:0000063 3-month-old stage Early adult stage that refers to a mouse which is over 3 and under 4 months old. Bgee:curator Early adult stage that refers to a mouse which is over 4 and under 5 months old. 5.0 21.0 4.0 16.0 mouse_developmental_stage MmusDv:0000064 4-month-old stage Early adult stage that refers to a mouse which is over 4 and under 5 months old. Bgee:curator 4 month-old stage that refers to a mouse which is over 112 days and under 120 days old. 17.0 16.0 MmusDv:0000162 mouse_developmental_stage MmusDv:0000065 16 weeks true 4 month-old stage that refers to a mouse which is over 112 days and under 120 days old. Bgee:curator 4 month-old stage that refers to a mouse which is over 119 days and under 127 days old. 18.0 17.0 MmusDv:0000163 mouse_developmental_stage MmusDv:0000066 17 weeks true 4 month-old stage that refers to a mouse which is over 119 days and under 127 days old. Bgee:curator 4 month-old stage that refers to a mouse which is over 126 days and under 134 days old. 19.0 18.0 MmusDv:0000164 mouse_developmental_stage MmusDv:0000067 18 weeks true 4 month-old stage that refers to a mouse which is over 126 days and under 134 days old. Bgee:curator 4 month-old stage that refers to a mouse which is over 133 days and under 141 days old. 20.0 19.0 MmusDv:0000165 mouse_developmental_stage MmusDv:0000068 19 weeks true 4 month-old stage that refers to a mouse which is over 133 days and under 141 days old. Bgee:curator Mouse stage that refers to a mouse which is over 5 and under 6 months old. 6.0 25.0 5.0 21.0 mouse_developmental_stage MmusDv:0000069 5-month-old stage Mouse stage that refers to a mouse which is over 5 and under 6 months old. Bgee:curator 4 month-old stage that refers to a mouse which is over 140 days and under 148 days old. 21.0 20.0 MmusDv:0000166 mouse_developmental_stage MmusDv:0000070 20 weeks true 4 month-old stage that refers to a mouse which is over 140 days and under 148 days old. Bgee:curator 5 month-old stage that refers to a mouse which is over 147 days and under 155 days old. 22.0 21.0 MmusDv:0000167 mouse_developmental_stage MmusDv:0000071 21 weeks true 5 month-old stage that refers to a mouse which is over 147 days and under 155 days old. Bgee:curator 5 month-old stage that refers to a mouse which is over 154 days and under 162 days old. 23.0 22.0 MmusDv:0000168 mouse_developmental_stage MmusDv:0000072 22 weeks true 5 month-old stage that refers to a mouse which is over 154 days and under 162 days old. Bgee:curator 5 month-old stage that refers to a mouse which is over 161 days and under 169 days old. 24.0 23.0 MmusDv:0000169 mouse_developmental_stage MmusDv:0000073 23 weeks true 5 month-old stage that refers to a mouse which is over 161 days and under 169 days old. Bgee:curator 5 month-old stage that refers to a mouse which is over 168 days and under 176 days old. 25.0 24.0 MmusDv:0000170 mouse_developmental_stage MmusDv:0000074 24 weeks true 5 month-old stage that refers to a mouse which is over 168 days and under 176 days old. Bgee:curator Late adult stage that refers to a mouse which is over 7 and under 15 months old. 15.0 7.0 30.0 MmusDv:0000078 MmusDv:0000079 MmusDv:0000080 MmusDv:0000135 mouse_developmental_stage MmusDv:0000075 This stage is commonly considered in the literature as the stage during which first evidence of loss of functional capability like hearing occurs in wild type mouse strain (see http://www.ncbi.nlm.nih.gov/pubmed/18259074). middle aged stage true Late adult stage that refers to a mouse which is over 7 and under 15 months old. http://research.jax.org/faculty/harrison/ger1vLifespan1.html#VD Late adult stage that refers to a mouse which is over 15 months old. 15.0 MmusDv:0000134 mouse_developmental_stage MmusDv:0000076 aged adult stage true Late adult stage that refers to a mouse which is over 15 months old. http://research.jax.org/faculty/harrison/ger1vLifespan1.html#VD Mouse stage that refers to a mouse which is over 6 and under 7 months old. 7.0 30.0 6.0 25.0 mouse_developmental_stage MmusDv:0000077 6-month-old stage Mouse stage that refers to a mouse which is over 6 and under 7 months old. Bgee:curator Mouse stage that refers to a mouse which is over 7 and under 8 months old. 8.0 7.0 30.0 mouse_developmental_stage MmusDv:0000078 7-month-old stage Mouse stage that refers to a mouse which is over 7 and under 8 months old. Bgee:curator Mouse stage that refers to a mouse which is over 8 and under 9 months old. 9.0 8.0 mouse_developmental_stage MmusDv:0000079 8-month-old stage Mouse stage that refers to a mouse which is over 8 and under 9 months old. Bgee:curator Mouse stage that refers to a mouse which is over 9 and under 10 months old. 10.0 9.0 mouse_developmental_stage MmusDv:0000080 9-month-old stage Mouse stage that refers to a mouse which is over 9 and under 10 months old. Bgee:curator Mouse stage that refers to a mouse which is over 10 and under 11 months old. 11.0 10.0 mouse_developmental_stage MmusDv:0000081 10-month-old stage Mouse stage that refers to a mouse which is over 10 and under 11 months old. Bgee:curator Mouse stage that refers to a mouse which is over 11 and under 12 months old. 12.0 11.0 mouse_developmental_stage MmusDv:0000082 11-month-old stage Mouse stage that refers to a mouse which is over 11 and under 12 months old. Bgee:curator Mouse stage that refers to a mouse which is over 12 and under 13 months old. 13.0 12.0 mouse_developmental_stage MmusDv:0000083 12-month-old stage Mouse stage that refers to a mouse which is over 12 and under 13 months old. Bgee:curator Mouse stage that refers to a mouse which is over 13 and under 14 months old. 14.0 13.0 mouse_developmental_stage MmusDv:0000084 13-month-old stage Mouse stage that refers to a mouse which is over 13 and under 14 months old. Bgee:curator Mouse stage that refers to a mouse which is over 14 and under 15 months old. 15.0 14.0 mouse_developmental_stage MmusDv:0000085 14-month-old stage Mouse stage that refers to a mouse which is over 14 and under 15 months old. Bgee:curator Mouse stage that refers to a mouse which is over 15 and under 16 months old. 16.0 15.0 mouse_developmental_stage MmusDv:0000086 15-month-old stage Mouse stage that refers to a mouse which is over 15 and under 16 months old. Bgee:curator Mouse stage that refers to a mouse which is over 16 and under 17 months old. 17.0 16.0 mouse_developmental_stage MmusDv:0000087 16-month-old stage Mouse stage that refers to a mouse which is over 16 and under 17 months old. Bgee:curator Mouse stage that refers to a mouse which is over 17 and under 18 months old. 18.0 17.0 mouse_developmental_stage MmusDv:0000088 17-month-old stage Mouse stage that refers to a mouse which is over 17 and under 18 months old. Bgee:curator Mouse stage that refers to a mouse which is over 18 and under 19 months old. 19.0 18.0 mouse_developmental_stage MmusDv:0000089 18-month-old stage Mouse stage that refers to a mouse which is over 18 and under 19 months old. Bgee:curator Mouse stage that refers to a mouse which is over 19 and under 20 months old. 20.0 19.0 mouse_developmental_stage MmusDv:0000090 19-month-old stage Mouse stage that refers to a mouse which is over 19 and under 20 months old. Bgee:curator Mouse stage that refers to a mouse which is over 20 months old. 20.0 mouse_developmental_stage MmusDv:0000091 20-month-old stage and over Mouse stage that refers to a mouse which is over 20 months old. Bgee:curator Mouse developmental stage that covers the period from birth until late adulthood. 19.0 0.0 UBERON:0000066 mouse_developmental_stage MmusDv:0000092 postnatal stage Mouse developmental stage that covers the period from birth until late adulthood. Bgee:curator Embryonic neurula stage during which the neural plate formation occurs and the allantoic bud elongates . TS11b mouse_developmental_stage MmusDv:0000093 Theiler stage 11b Embryonic neurula stage during which the neural plate formation occurs and the allantoic bud elongates . http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_11 Embryonic neurula stage during which the neural plate formation occurs and the head folds are formed while the neural groove becomes visible. TS11c mouse_developmental_stage MmusDv:0000094 Theiler stage 11c Embryonic neurula stage during which the neural plate formation occurs and the head folds are formed while the neural groove becomes visible. http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_11 Embryonic neurula stage during which the neural plate formation occurs and the head folds continue to enlarge while the foregut pocket begins to form. TS11d mouse_developmental_stage MmusDv:0000095 Theiler stage 11d Embryonic neurula stage during which the neural plate formation occurs and the head folds continue to enlarge while the foregut pocket begins to form. http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_11 Immature stage that covers the period from birth until end of the first week. 1.0 19.0 0.0 MmusDv:0000036 MmusDv:0000139 mouse_developmental_stage MmusDv:0000096 This term was made obsolete due to discussion at https://github.com/obophenotype/developmental-stage-ontologies/issues/23. [ANiknejad] early immature stage true Immature stage that covers the period from birth until end of the first week. Bgee:curator Mature stage that refers to an adult mouse which is over 7 months old. 7.0 30.0 MmusDv:0000134 MmusDv:0000135 UBERON:0007222 mouse_developmental_stage MmusDv:0000097 late adult stage true Mature stage that refers to an adult mouse which is over 7 months old. http://research.jax.org/faculty/harrison/ger1vLifespan1.html#VD 6 month-old stage that refers to a mouse which is over 175 days and under 183 days old. 26.0 25.0 MmusDv:0000171 mouse_developmental_stage MmusDv:0000098 25 weeks true 6 month-old stage that refers to a mouse which is over 175 days and under 183 days old. Bgee:curator 6 month-old stage that refers to a mouse which is over 182 days and under 190 days old. 27.0 26.0 MmusDv:0000172 mouse_developmental_stage MmusDv:0000099 26 weeks true 6 month-old stage that refers to a mouse which is over 182 days and under 190 days old. Bgee:curator 6 month-old stage that refers to a mouse which is over 189 days and under 197 days old. 28.0 27.0 MmusDv:0000173 mouse_developmental_stage MmusDv:0000100 27 weeks true 6 month-old stage that refers to a mouse which is over 189 days and under 197 days old. Bgee:curator 6 month-old stage that refers to a mouse which is over 196 days and under 204 days old. 29.0 28.0 MmusDv:0000174 mouse_developmental_stage MmusDv:0000101 28 weeks true 6 month-old stage that refers to a mouse which is over 196 days and under 204 days old. Bgee:curator 6 month-old stage that refers to a mouse which is over 203 days and under 211 days old. 30.0 29.0 MmusDv:0000175 mouse_developmental_stage MmusDv:0000102 29 weeks true 6 month-old stage that refers to a mouse which is over 203 days and under 211 days old. Bgee:curator Theiler developmental stage 9 defined by advanced endometrial reaction and during which the egg-cylinder stage advances with the first evidence of an embryonic axis. TS09a Theiler stage 9 mouse_developmental_stage MmusDv:0000103 Theiler stage 09a Theiler developmental stage 9 defined by advanced endometrial reaction and during which the egg-cylinder stage advances with the first evidence of an embryonic axis. http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Stage_9a Theiler developmental stage 9 defined by advanced endometrial reaction and during which the first mesodermal cells are produced by gastrulation late in this stage. TS09b Theiler stage 9 mouse_developmental_stage MmusDv:0000104 Theiler stage 09b Theiler developmental stage 9 defined by advanced endometrial reaction and during which the first mesodermal cells are produced by gastrulation late in this stage. http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Stage_9b Theiler developmental stage 10 during which the tissue at the posterior end of the primitive streak bulges into the pro-amniotic cavity and forms the amniotic fold. TS10a mouse_developmental_stage MmusDv:0000105 Refers to MS (mid-streak) stage in Downs and Davies staging of gastrulating mouse embryos (PMID: 8269852, 1993). Theiler stage 10a Theiler developmental stage 10 during which the tissue at the posterior end of the primitive streak bulges into the pro-amniotic cavity and forms the amniotic fold. http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Stage_10a Theiler developmental stage 10 during which small cavities coalesce to form a single cavity in the mesoderm of the posterior amniotic fold, the exocoelom. TS10b mouse_developmental_stage MmusDv:0000106 Refers to MS-LS (mid-streak to late streak) stage in Downs and Davies staging of gastrulating mouse embryos, 1993 (see http://www.ncbi.nlm.nih.gov/pubmed/8269852). Theiler stage 10b Theiler developmental stage 10 during which small cavities coalesce to form a single cavity in the mesoderm of the posterior amniotic fold, the exocoelom. http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_10b Theiler developmental stage 10 during which the allantoic bud first appears, gastrulation continues and the node becomes visible. TS10c mouse_developmental_stage MmusDv:0000107 Refers to MS-LS (mid-streak to late streak) stage in Downs and Davies staging of gastrulating mouse embryos, 1993 (see http://www.ncbi.nlm.nih.gov/pubmed/8269852). Theiler stage 10c Theiler developmental stage 10 during which the allantoic bud first appears, gastrulation continues and the node becomes visible. http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_10c Theiler developmental stage 12 defined by unturned embryo with first appearance of somite pairs 1-4 and during which the allantois extends further into the exocoelom. Maxillary components of the 1st branchial arch become prominent. The preotic sulcus is visible in the 2-3 somite embryo. The cardiogenic plate begins to form and the foregut pocket is clearly visible. TS12a mouse_developmental_stage MmusDv:0000108 Embryonic age 8 dpc (day post coitum). Refers to human CarnegieStage09. Theiler stage 12a Theiler developmental stage 12 defined by unturned embryo with first appearance of somite pairs 1-4 and during which the allantois extends further into the exocoelom. Maxillary components of the 1st branchial arch become prominent. The preotic sulcus is visible in the 2-3 somite embryo. The cardiogenic plate begins to form and the foregut pocket is clearly visible. http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_12a Theiler developmental stage 12 defined by unturned embryo with first appearance of somite pairs 5-7 and during which neural closure occurs in the region of the 4th and 5th somites, extending in both directions from this site. Headfolds are particularly prominent. Optic placodes are first evident and become indented to form the optic pits. The heart rudiment develops rapidly. The allantois contacts the chorion at the end of this stage. TS12b mouse_developmental_stage MmusDv:0000109 Embryonic age 8 dpc (day post coitum). Refers to human CarnegieStage09. Theiler stage 12b Theiler developmental stage 12 defined by unturned embryo with first appearance of somite pairs 5-7 and during which neural closure occurs in the region of the 4th and 5th somites, extending in both directions from this site. Headfolds are particularly prominent. Optic placodes are first evident and become indented to form the optic pits. The heart rudiment develops rapidly. The allantois contacts the chorion at the end of this stage. http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_12b Mouse developmental stage that refers to a sexually mature adult mouse which is over 6 weeks old. 1.5 6.0 UBERON:0000113 mature mouse_developmental_stage MmusDv:0000110 mature stage Mouse developmental stage that refers to a sexually mature adult mouse which is over 6 weeks old. Bgee:curator Embryonic neurula stage during which the neural plate formation occurs and the amniotic cavity is sealed off into three distinct cavities - the amniotic cavity, the exocoelom and the ectoplacental cleft. TS11a mouse_developmental_stage MmusDv:0000111 Theiler stage 11a Embryonic neurula stage during which the neural plate formation occurs and the amniotic cavity is sealed off into three distinct cavities - the amniotic cavity, the exocoelom and the ectoplacental cleft. http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_11 Mouse developmental stage that covers the period from P4 starting at TS28 until 5 weeks old. 6.0 0.6 MmusDv:0000139 MmusDv:0000140 MmusDv:0000141 MmusDv:0000142 MmusDv:0000143 MmusDv:0000144 MmusDv:0000145 MmusDv:0000146 MmusDv:0000147 MmusDv:0000148 MmusDv:0000149 MmusDv:0000150 mouse_developmental_stage infant stage MmusDv:0000112 It is commonly accepted that mouse reaches sexual maturity by six weeks of age (see http://www.ahc.umn.edu/rar/breeding.html). We start this stage at P4 because TS27 'newborn' stage is not defined as a postnatal stage. premature stage true Mouse developmental stage that covers the period from P4 starting at TS28 until 5 weeks old. Bgee:curator Premature stage that refers to the newborn mouse which is over 4 days and under 8 days old. 1.0 0.6 MmusDv:0000139 mouse_developmental_stage MmusDv:0000113 This stage starts at P4. 4-7 days true Premature stage that refers to the newborn mouse which is over 4 days and under 8 days old. Bgee:curator Immature stage that refers to a mouse which is over 4 and under 5 days old. 5.0 4.0 mouse_developmental_stage MmusDv:0000114 4-day-old stage Immature stage that refers to a mouse which is over 4 and under 5 days old. Bgee:curator Immature stage that refers to a mouse which is over 5 and under 6 days old. 6.0 5.0 mouse_developmental_stage MmusDv:0000115 5-day-old stage Immature stage that refers to a mouse which is over 5 and under 6 days old. Bgee:curator Immature stage that refers to a mouse which is over 6 and under 7 days old. 7.0 6.0 mouse_developmental_stage MmusDv:0000116 6-day-old stage Immature stage that refers to a mouse which is over 6 and under 7 days old. Bgee:curator Immature stage that refers to a mouse which is over 7 and under 8 days old. 8.0 7.0 mouse_developmental_stage MmusDv:0000117 7-day-old stage Immature stage that refers to a mouse which is over 7 and under 8 days old. Bgee:curator Immature stage that refers to a mouse which is over 8 and under 9 days old. 9.0 8.0 mouse_developmental_stage MmusDv:0000118 8-day-old stage Immature stage that refers to a mouse which is over 8 and under 9 days old. Bgee:curator Immature stage that refers to a mouse which is over 9 and under 10 days old. 10.0 9.0 mouse_developmental_stage MmusDv:0000119 9-day-old stage Immature stage that refers to a mouse which is over 9 and under 10 days old. Bgee:curator Immature stage that refers to a mouse which is over 10 and under 11 days old. 11.0 10.0 mouse_developmental_stage MmusDv:0000120 10-day-old stage Immature stage that refers to a mouse which is over 10 and under 11 days old. Bgee:curator Immature stage that refers to a mouse which is over 11 and under 12 days old. 12.0 11.0 mouse_developmental_stage MmusDv:0000121 11-day-old stage Immature stage that refers to a mouse which is over 11 and under 12 days old. Bgee:curator Immature stage that refers to a mouse which is over 12 and under 13 days old. 13.0 12.0 mouse_developmental_stage MmusDv:0000122 12-day-old stage Immature stage that refers to a mouse which is over 12 and under 13 days old. Bgee:curator Immature stage that refers to a mouse which is over 13 and under 14 days old. 14.0 13.0 mouse_developmental_stage MmusDv:0000123 13-day-old stage Immature stage that refers to a mouse which is over 13 and under 14 days old. Bgee:curator Mouse stage that refers to a mouse which is over 20 and under 21 months old. 21.0 20.0 mouse_developmental_stage MmusDv:0000124 20-month-old stage Mouse stage that refers to a mouse which is over 20 and under 21 months old. Bgee:curator Mouse stage that refers to a mouse which is over 21 and under 22 months old. 22.0 21.0 mouse_developmental_stage MmusDv:0000125 21-month-old stage Mouse stage that refers to a mouse which is over 21 and under 22 months old. Bgee:curator Mouse stage that refers to a mouse which is over 22 and under 23 months old. 23.0 22.0 mouse_developmental_stage MmusDv:0000126 22-month-old stage Mouse stage that refers to a mouse which is over 22 and under 23 months old. Bgee:curator Mouse stage that refers to a mouse which is over 23 and under 24 months old. 24.0 23.0 mouse_developmental_stage MmusDv:0000127 23-month-old stage Mouse stage that refers to a mouse which is over 23 and under 24 months old. Bgee:curator Mouse stage that refers to a mouse which is over 24 and under 25 months old. 25.0 24.0 mouse_developmental_stage MmusDv:0000128 24-month-old stage Mouse stage that refers to a mouse which is over 24 and under 25 months old. Bgee:curator Mouse stage that refers to a mouse which is over 25 and under 26 months old. 26.0 25.0 mouse_developmental_stage MmusDv:0000129 25-month-old stage Mouse stage that refers to a mouse which is over 25 and under 26 months old. Bgee:curator Mouse stage that refers to a mouse which is over 26 and under 27 months old. 27.0 26.0 mouse_developmental_stage MmusDv:0000130 26-month-old stage Mouse stage that refers to a mouse which is over 26 and under 27 months old. Bgee:curator Mouse stage that refers to a mouse which is over 27 and under 28 months old. 28.0 27.0 mouse_developmental_stage MmusDv:0000131 27-month-old stage Mouse stage that refers to a mouse which is over 27 and under 28 months old. Bgee:curator Mouse stage that refers to a mouse which is over 28 and under 29 months old. 29.0 28.0 mouse_developmental_stage MmusDv:0000132 28-month-old stage Mouse stage that refers to a mouse which is over 28 and under 29 months old. Bgee:curator Mouse stage that refers to a mouse which is over 29 and under 30 months old. 30.0 29.0 mouse_developmental_stage MmusDv:0000133 29-month-old stage Mouse stage that refers to a mouse which is over 29 and under 30 months old. Bgee:curator Mature stage that refers to an adult mouse which is over 18 months old. 18.0 UBERON:0007222 mouse_developmental_stage MmusDv:0000134 Mice from 18 months are considered as old and show presence of senescent changes in almost all biomarkers (see https://www.jax.org/news-and-insights/jax-blog/2017/november/when-are-mice-considered-old). late adult stage Mature stage that refers to an adult mouse which is over 18 months old. Bgee:curator Prime adult stage that refers to a mouse which is over 10 and under 18 months old. 18.0 10.0 mouse_developmental_stage MmusDv:0000135 Mice middle-aged group is used in the literature to investigate progressive age-related changes. For sake of consistency in age continuity, we adapt the age limits from https://www.jax.org/news-and-insights/jax-blog/2017/november/when-are-mice-considered-old. middle aged stage Prime adult stage that refers to a mouse which is over 10 and under 18 months old. Bgee:curator Mature stage that refers to a adult mouse which is over 6 weeks and under 18 months old. 18.0 1.5 6.0 UBERON:0018241 mouse_developmental_stage MmusDv:0000136 Mice over 18 months old are considered as old (see https://www.jax.org/news-and-insights/jax-blog/2017/november/when-are-mice-considered-old). prime adult stage Mature stage that refers to a adult mouse which is over 6 weeks and under 18 months old. Bgee:curator Mature stage that refers to a mouse which is over 3 and under 7 months old. 7.0 3.0 mouse_developmental_stage MmusDv:0000137 This stage is often used as the reference group for any age change in aging studies. Correlates to humans from 20 - 30 years old (see https://www.jax.org/news-and-insights/jax-blog/2017/november/when-are-mice-considered-old). 3-6 month-old mature stage Mature stage that refers to a mouse which is over 3 and under 7 months old. Bgee:curator Mouse developmental stage that covers the period from birth until 22 days old, at which point individuals wean. 23.0 0.0 UBERON:0018685 mouse_developmental_stage MmusDv:0000138 Age of weaning is 22 days (see https://genomics.senescence.info/species/entry.php?species=Mus_musculus). nursing stage Mouse developmental stage that covers the period from birth until 22 days old, at which point individuals wean. Bgee:curator Immature stage that refers to the newborn mouse which is over 4 days and under 7 days old. 7.0 1.0 4.0 0.6 mouse_developmental_stage MmusDv:0000139 This stage starts at P4. 4-6 days Immature stage that refers to the newborn mouse which is over 4 days and under 7 days old. Bgee:curator Immature stage that refers to a mouse which is over 7 days and under 14 days old. 14.0 2.0 7.0 1.0 mouse_developmental_stage MmusDv:0000140 1-week-old stage Immature stage that refers to a mouse which is over 7 days and under 14 days old. Bgee:curator Immature stage that refers to a mouse which is over 14 days and under 21 days old. 21.0 3.0 14.0 2.0 mouse_developmental_stage MmusDv:0000141 2-week-old stage Immature stage that refers to a mouse which is over 14 days and under 21 days old. Bgee:curator Immature stage that refers to a mouse which is over 21 and under 22 days old. 22.0 21.0 mouse_developmental_stage MmusDv:0000142 21-day-old stage Immature stage that refers to a mouse which is over 21 and under 22 days old. Bgee:curator Immature stage that refers to a mouse which is over 22 and under 23 days old. 23.0 22.0 mouse_developmental_stage MmusDv:0000143 22-day-old stage Immature stage that refers to a mouse which is over 22 and under 23 days old. Bgee:curator Immature stage that refers to a mouse which is over 23 and under 24 days old. 24.0 23.0 mouse_developmental_stage MmusDv:0000144 23-day-old stage Immature stage that refers to a mouse which is over 23 and under 24 days old. Bgee:curator Immature stage that refers to a mouse which is over 24 and under 25 days old. 25.0 24.0 mouse_developmental_stage MmusDv:0000145 24-day-old stage Immature stage that refers to a mouse which is over 24 and under 25 days old. Bgee:curator Immature stage that refers to a mouse which is over 25 and under 26 days old. 22.0 21.0 mouse_developmental_stage MmusDv:0000146 25-day-old stage Immature stage that refers to a mouse which is over 25 and under 26 days old. Bgee:curator Immature stage that refers to a mouse which is over 26 and under 27 days old. 27.0 26.0 mouse_developmental_stage MmusDv:0000147 26-day-old stage Immature stage that refers to a mouse which is over 26 and under 27 days old. Bgee:curator Immature stage that refers to a mouse which is over 27 and under 28 days old. 28.0 27.0 mouse_developmental_stage MmusDv:0000148 27-day-old stage Immature stage that refers to a mouse which is over 27 and under 28 days old. Bgee:curator Immature stage that refers to a mouse which is over 28 days and under 35 days old. 35.0 5.0 28.0 4.0 mouse_developmental_stage MmusDv:0000149 4-week-old stage Immature stage that refers to a mouse which is over 28 days and under 35 days old. Bgee:curator Immature stage that refers to a mouse which is over 35 days and under 42 days old. 42.0 6.0 35.0 5.0 mouse_developmental_stage MmusDv:0000150 This stage is usually the stage during which the sexual maturity occurs. 5-week-old stage Immature stage that refers to a mouse which is over 35 days and under 42 days old. Bgee:curator Prime adult stage that refers to a mouse which is over 42 days and under 49 days old. 49.0 7.0 42.0 6.0 mouse_developmental_stage MmusDv:0000151 This stage is commonly considered in the literature as the milestone that distinguishes between sexually immmature and mature stages (see http://www.ahc.umn.edu/rar/breeding.html). 6-week-old stage Prime adult stage that refers to a mouse which is over 42 days and under 49 days old. Bgee:curator Prime adult stage that refers to a mouse which is over 49 days and under 56 days old. 56.0 8.0 49.0 7.0 mouse_developmental_stage MmusDv:0000152 This stage is commonly considered in the literature as the milestone that distinguishes between sexually immmature and mature stages (see http://www.ahc.umn.edu/rar/breeding.html). 7-week-old stage Prime adult stage that refers to a mouse which is over 49 days and under 56 days old. Bgee:curator Prime adult stage that refers to a sexually mature mouse under 10 months old. 10.0 1.5 mouse_developmental_stage MmusDv:0000153 This stage is adapted from https://www.jax.org/news-and-insights/jax-blog/2017/november/when-are-mice-considered-old. young adult stage Prime adult stage that refers to a sexually mature mouse under 10 months old. Bgee:curator Mouse stage that refers to a mouse which is over 56 days and under 63 days old. 63.0 9.0 56.0 8.0 mouse_developmental_stage MmusDv:0000154 8-week-old stage Mouse stage that refers to a mouse which is over 56 days and under 63 days old. Bgee:curator Mouse stage that refers to a mouse which is over 63 days and under 70 days old. 70.0 10.0 63.0 9.0 mouse_developmental_stage MmusDv:0000155 9-week-old stage Mouse stage that refers to a mouse which is over 63 days and under 70 days old. Bgee:curator Mouse stage that refers to a mouse which is over 70 days and under 77 days old. 77.0 11.0 70.0 10.0 mouse_developmental_stage MmusDv:0000156 10-week-old stage Mouse stage that refers to a mouse which is over 70 days and under 77 days old. Bgee:curator Mouse stage that refers to a mouse which is over 77 days and under 84 days old. 84.0 12.0 77.0 11.0 mouse_developmental_stage MmusDv:0000157 11-week-old stage Mouse stage that refers to a mouse which is over 77 days and under 84 days old. Bgee:curator Mouse stage that refers to a mouse which is over 84 days and under 91 days old. 91.0 13.0 84.0 12.0 mouse_developmental_stage MmusDv:0000158 12-week-old stage Mouse stage that refers to a mouse which is over 84 days and under 91 days old. Bgee:curator Mouse stage that refers to a mouse which is over 91 days and under 98 days old. 98.0 14.0 91.0 13.0 mouse_developmental_stage MmusDv:0000159 13-week-old stage Mouse stage that refers to a mouse which is over 91 days and under 98 days old. Bgee:curator Mouse stage that refers to a mouse which is over 98 days and under 105 days old. 105.0 15.0 98.0 14.0 mouse_developmental_stage MmusDv:0000160 14-week-old stage Mouse stage that refers to a mouse which is over 98 days and under 105 days old. Bgee:curator Mouse stage that refers to a mouse which is over 105 days and under 112 days old. 112.0 16.0 105.0 15.0 mouse_developmental_stage MmusDv:0000161 15-week-old stage Mouse stage that refers to a mouse which is over 105 days and under 112 days old. Bgee:curator Mouse stage that refers to a mouse which is over 112 days and under 119 days old. 119.0 17.0 112.0 16.0 mouse_developmental_stage MmusDv:0000162 16-week-old stage Mouse stage that refers to a mouse which is over 112 days and under 119 days old. Bgee:curator Mouse stage that refers to a mouse which is over 119 days and under 126 days old. 126.0 18.0 119.0 17.0 mouse_developmental_stage MmusDv:0000163 17-week-old stage Mouse stage that refers to a mouse which is over 119 days and under 126 days old. Bgee:curator Mouse stage that refers to a mouse which is over 126 days and under 133 days old. 133.0 19.0 126.0 18.0 mouse_developmental_stage MmusDv:0000164 18-week-old stage Mouse stage that refers to a mouse which is over 126 days and under 133 days old. Bgee:curator Mouse stage that refers to a mouse which is over 133 days and under 140 days old. 140.0 20.0 133.0 19.0 mouse_developmental_stage MmusDv:0000165 19-week-old stage Mouse stage that refers to a mouse which is over 133 days and under 140 days old. Bgee:curator Mouse stage that refers to a mouse which is over 140 days and under 147 days old. 147.0 21.0 140.0 20.0 mouse_developmental_stage MmusDv:0000166 20-week-old stage Mouse stage that refers to a mouse which is over 140 days and under 147 days old. Bgee:curator Mouse stage that refers to a mouse which is over 147 days and under 154 days old. 154.0 22.0 147.0 21.0 mouse_developmental_stage MmusDv:0000167 21-week-old stage Mouse stage that refers to a mouse which is over 147 days and under 154 days old. Bgee:curator Mouse stage that refers to a mouse which is over 154 days and under 161 days old. 161.0 23.0 154.0 22.0 mouse_developmental_stage MmusDv:0000168 22-week-old stage Mouse stage that refers to a mouse which is over 154 days and under 161 days old. Bgee:curator Mouse stage that refers to a mouse which is over 161 days and under 168 days old. 168.0 24.0 161.0 23.0 mouse_developmental_stage MmusDv:0000169 23-week-old stage Mouse stage that refers to a mouse which is over 161 days and under 168 days old. Bgee:curator Mouse stage that refers to a mouse which is over 168 days and under 175 days old. 175.0 25.0 168.0 24.0 mouse_developmental_stage MmusDv:0000170 24-week-old stage Mouse stage that refers to a mouse which is over 168 days and under 175 days old. Bgee:curator Mouse stage that refers to a mouse which is over 175 days and under 182 days old. 182.0 26.0 175.0 25.0 mouse_developmental_stage MmusDv:0000171 25-week-old stage Mouse stage that refers to a mouse which is over 175 days and under 182 days old. Bgee:curator Mouse stage that refers to a mouse which is over 182 days and under 189 days old. 189.0 27.0 182.0 26.0 mouse_developmental_stage MmusDv:0000172 26-week-old stage Mouse stage that refers to a mouse which is over 182 days and under 189 days old. Bgee:curator Mouse stage that refers to a mouse which is over 189 days and under 196 days old. 196.0 28.0 189.0 27.0 mouse_developmental_stage MmusDv:0000173 27-week-old stage Mouse stage that refers to a mouse which is over 189 days and under 196 days old. Bgee:curator Mouse stage that refers to a mouse which is over 196 days and under 203 days old. 203.0 29.0 196.0 28.0 mouse_developmental_stage MmusDv:0000174 28-week-old stage Mouse stage that refers to a mouse which is over 196 days and under 203 days old. Bgee:curator Mouse stage that refers to a mouse which is over 203 days and under 210 days old. 210.0 30.0 203.0 29.0 mouse_developmental_stage MmusDv:0000175 29-week-old stage Mouse stage that refers to a mouse which is over 203 days and under 210 days old. Bgee:curator Mouse stage that refers to a mouse which is over 30 and under 31 months old. 31.0 30.0 mouse_developmental_stage MmusDv:0000176 30-month-old stage Mouse stage that refers to a mouse which is over 30 and under 31 months old. Bgee:curator Nursing stage that follows the neonate stage in mouse and ends at weaning, at 22 days old. 23.0 1.0 4.0 0.6 UBERON:0034920 mouse_developmental_stage MmusDv:0000177 infant stage Nursing stage that follows the neonate stage in mouse and ends at weaning, at 22 days old. Bgee:curator Mouse stage that refers to a weaned mouse which is over 23 days old, while still being an sexually immature mouse. 24.0 23.0 UBERON:0034919 mouse_developmental_stage MmusDv:0000178 juvenile stage Mouse stage that refers to a weaned mouse which is over 23 days old, while still being an sexually immature mouse. Bgee:curator