]> 2015-12-10 Alan Ruttenberg Alan Ruttenberg Harrison Strachan Asiyah Yu Lin He Zhang Jingshan Huang This is the release of December 12, 2015. It will always be available at http://purl.obolibrary.org/ncro/2015-12-10/ncro.owl This ontology is currently undergoing changes. ID deprecation policies will start in the next couple of months. In the mean time, identifiers may be deleted and not marked obsolete. definition antisymmetric property is_about_grouped_miRNA 2015-05-16T19:28:03Z He_Zhang is_about_miRNA is_about_miRNA_target_gene is_classified_into_gene_family_group 2015-05-16T19:27:05Z He_Zhang is_gene_template_of_mRNA is_model_of_disease is_predicted_target_of 2015-05-17T07:52:46Z He_Zhang miRNA_expressed_in_tissue regulate_miRNA_transcription regulate_mRNA_translation has_predicted_target 2015-05-17T07:51:13Z tRNA rRNA RNA snRNA circRNA miRNA_target_gene_primary_transcript miRNA_target_gene_mRNA miRNA_and_target_gene_binding fly_miRNA c_elegans_miRNA bacterial_miRNA virus_miRNA non_mammalian_miRNA mammalian_miRNA miRNA_expression protein_miRNA_promoter_binding promoter_of_miRNA miRNA_transcription_initiation transcription_of_miRNA animal_study_model miRNA_target_gene 2015-05-25T15:37:18Z environmental_variable 2013-09-28T19:15:26Z An experimental variable is the variable that is used in an experiment and is known as the dependent variable that can be manipulated and is being studied HeZhang gene_sequence 2013-09-28T19:15:26Z HeZhang pressure 2013-09-28T19:16:26Z HeZhang The ratio of force to the area over which that force is distributed temperature 2013-09-28T19:16:26Z HeZhang Numerical measure of hot or cold high_pressure 2013-09-28T19:17:41Z HeZhang low_pressure 2013-09-28T19:17:41Z HeZhang normal_pressure 2013-09-28T19:17:41Z HeZhang high_temperature 2013-09-28T19:18:33Z HeZhang low_temperature 2013-09-28T19:18:33Z HeZhang normal_temperature 2013-09-28T19:18:33Z HeZhang harmful_role "A harmful role or activity realizeable by some agent in the human body" 2013-09-29T18:27:09Z HeZhang harmful_environmental_effect "Harmful physical agents" 2013-09-29T18:29:20Z HeZhang pathogenicity ""Germs" -- foreign microorganisms capable of causing disease" 2013-09-29T18:29:20Z HeZhang The potential capacity of certain species of microbes to cause a disease toxic_activity "Harmful chemical agents" 2013-09-29T18:29:20Z HeZhang carcinogenicity The ability or tendency to produce cancer. 2013-09-29T18:30:22Z HeZhang virus 2013-10-01T23:27:46Z HeZhang Small infectious agent that replicates only inside the living cells of other organisms adult_tissue 2013-10-01T23:32:05Z HeZhang embryonic_tissue "Tissues existing in the early embryonic stages of development" 2013-10-01T23:32:05Z HeZhang Tissue in an embryo connective_tissue "Tissues originating from mesoderm and performing a structural or connective function between other tissues" 2013-10-01T23:33:33Z HeZhang Tissue that connects, supports, binds, or separates other tissues or organs, typically having relatively few cells embedded in an amorphous matrix, often with collagen or other fibers, and including cartilaginous, fatty, and elastic tissues. epithelia_tissue "Tissue lining body structures and forming glands" 2013-10-01T23:33:33Z HeZhang Membranous tissue covering internal organs and other internal surfaces of the body. muscle_tissue "Tissue forming muscles - capable of generating movement of body structures" 2013-10-01T23:33:33Z HeZhang Muscle tissue is one of four basic biological tissues present in animals. It is a soft tissue that composes muscles. It is formed during embryo development in a process known as myogenesis. nerve_tissue "Tissue forming nerves and neural structures like the brain and spinal cord, used for coordinating bodily functions." 2013-10-01T23:33:33Z HeZhang Tissue composed of neurons. adipose_tissue "Fat tissue" 2013-10-01T23:34:55Z A kind of body tissue containing stored fat that serves as a source of energy; it also cushions and insulates vital organs. HeZhang blood "Blood tissue, including red and white blood cells" 2013-10-01T23:34:55Z Bodily fluid in animals that delivers necessary substances such as nutrients and oxygen to the cells and transports metabolic waste products away. HeZhang bone "Bone tissue - provides structural framework for body with high compressive strength" 2013-10-01T23:34:55Z HeZhang Rigid organs that constitute part of the endoskeleton of vertebrates. cartilage "Tough tissue that connects bones and gives form to many of the soft structures of the body" 2013-10-01T23:34:55Z A tough, elastic, fibrous connective tissue found in various parts of the body, such as the joints, outer ear, and larynx. HeZhang cardiac_muscle "Muscle cells of the heart" 2013-10-01T23:36:04Z HeZhang Type of involuntary striated muscle found in the walls and histological foundation of the heart. skeletal_muscle "Muscle cells of skeletal muscle - those that execute voluntary movement of the skeleton" 2013-10-01T23:36:04Z Form of striated muscle tissue which is under the control of the somatic nervous system. HeZhang smooth_muscle "Muscle cells of smooth muscle - found in digestive tract and blood vessels, execute involuntary movement" 2013-10-01T23:36:04Z HeZhang Responsible for the contractility of hollow organs, such as blood vessels, the gastrointestinal tract, the bladder, or the uterus. ectoderm "The outer layer of cells in the early embryo" 2013-10-03T23:21:30Z HeZhang Outermost of the three primary germ layers of an embryo, from which the epidermis, nervous tissue, and, in vertebrates, sense organs develop. endoderm "The inner layer of cells in the early embryo" 2013-10-03T23:21:30Z HeZhang Innermost of the three primary germ layers of an animal embryo, developing into the gastrointestinal tract, the lungs, and associated structures. mesoderm "The middle layer of cells in the early embryo" 2013-10-03T23:21:30Z HeZhang Middle embryonic germ layer, lying between the ectoderm and the endoderm, from which connective tissue, muscle, bone, and the urogenital and circulatory systems develop. treatment 2013-10-03T23:37:16Z HeZhang pharmaceutical_treatment 2013-10-04T20:10:02Z physical_therapy 2013-10-04T20:10:02Z A health care profession primarily concerned with the remediation of impairments and disabilities and the promotion of mobility, functional ability, quality of life and movement potential through examination, evaluation, diagnosis and physical intervention. psychological_treatment 2013-10-04T20:10:02Z surgery 2013-10-04T20:10:02Z Branch of medicine that deals with the diagnosis and treatment of injury, deformity, and disease by manual and instrumental means. analgesic_treatment 2013-10-04T20:19:18Z antibiotic_treatment 2013-10-04T20:19:18Z antihyperlipidemic_treatment 2013-10-04T20:19:18Z antihypertensive_treatment 2013-10-04T20:19:18Z chemotherapy 2013-10-04T20:19:18Z Treatment of cancer with one or more cytotoxic antineoplastic drugs. immunosuppressive_therapy 2013-10-04T20:19:18Z Immunosuppression involves an act that reduces the activation or efficacy of the immune system. radiation_release 2013-10-04T20:24:14Z The treatment of disease, esp. cancer, using X-rays or similar forms of radiation. cellular_organism 2013-10-07T00:19:58Z An organism of microscopic or submicroscopic size, especially a bacterium or protozoan archaea 2013-10-07T00:31:14Z HeZhang microorganisms that are similar to bacteria in size and simplicity of structure but radically different in molecular organization. They are now believed to constitute an ancient intermediate group between the bacteria and eukaryotes bacteria 2013-10-07T00:31:14Z HeZhang a member of a large group of unicellular microorganisms that have cell walls but lack organelles and an organized nucleus, including some that can cause diseas mouse_miRNA TE_juxtaposition 2013-10-25T16:05:06Z HeZhang TE_insertion 2013-10-25T16:03:19Z positive_strand_insertion 2013-10-25T16:17:26Z HeZhang negative_strand_insertion 2013-10-25T16:17:26Z HeZhang human_miRNA 2015-05-16T19:26:04Z He_Zhang hsa-mir-585 miRBase:MI0003592 hsa-mir-620 miRBase:MI0003634 hsa-mir-659 miRBase:MI0003683 hsa-mir-2113 miRBase:MI0003939 hsa-mir-1229 miRBase:MI0006319 hsa-mir-1234 miRBase:MI0006324 hsa-mir-548o miRBase:MI0006402 hsa-mir-1279 miRBase:MI0006426 hsa-mir-1321 miRBase:MI0006652 hsa-mir-1470 miRBase:MI0007075 hsa-mir-1539 miRBase:MI0007260 hsa-mir-1973 miRBase:MI0009983 hsa-mir-2052 miRBase:MI0010486 hsa-mir-2053 miRBase:MI0010487 hsa-mir-2054 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miRBase:MIPF0000651 mir-1276 miRBase:MIPF0000652 mir-630 miRBase:MIPF0000653 mir-559 miRBase:MIPF0000656 mir-645 miRBase:MIPF0000657 mir-302_2 miRBase:MIPF0000658 mir-1288 miRBase:MIPF0000660 mir-610 miRBase:MIPF0000661 mir-635 miRBase:MIPF0000662 mir-1322 miRBase:MIPF0000663 mir-1181 miRBase:MIPF0000665 mir-1249 miRBase:MIPF0000667 mir-1183 miRBase:MIPF0000668 mir-1247 miRBase:MIPF0000669 mir-1825 miRBase:MIPF0000670 mir-1204 miRBase:MIPF0000671 mir-617 miRBase:MIPF0000672 mir-1182 miRBase:MIPF0000673 mir-1275 miRBase:MIPF0000674 mir-1292 miRBase:MIPF0000675 mir-1295 miRBase:MIPF0000676 mir-766 miRBase:MIPF0000677 mir-641 miRBase:MIPF0000679 mir-588 miRBase:MIPF0000681 mir-1286 miRBase:MIPF0000682 mir-1258 miRBase:MIPF0000684 mir-1263 miRBase:MIPF0000687 mir-1265 miRBase:MIPF0000688 mir-1236 miRBase:MIPF0000689 mir-943 miRBase:MIPF0000690 mir-1293 miRBase:MIPF0000691 mir-1281 miRBase:MIPF0000695 mir-1250 miRBase:MIPF0000696 mir-759 miRBase:MIPF0000706 mir-764 miRBase:MIPF0000707 mir-761 miRBase:MIPF0000709 mir-1193 miRBase:MIPF0000714 mir-718 miRBase:MIPF0000721 mir-1287 miRBase:MIPF0000725 mir-769 miRBase:MIPF0000727 mir-670 miRBase:MIPF0000734 mir-1301 miRBase:MIPF0000742 mir-711 miRBase:MIPF0000748 mir-571 miRBase:MIPF0000757 mir-602 miRBase:MIPF0000767 mir-1912 miRBase:MIPF0000768 mir-1468 miRBase:MIPF0000777 mir-606 miRBase:MIPF0000780 mir-1180 miRBase:MIPF0000789 mir-623 miRBase:MIPF0000798 mir-1261 miRBase:MIPF0000802 mir-596 miRBase:MIPF0000808 mir-3130 miRBase:MIPF0000845 mir-3202 miRBase:MIPF0000846 mir-1270 miRBase:MIPF0000877 mir-3156 miRBase:MIPF0000891 mir-3180 miRBase:MIPF0000894 mir-3179 miRBase:MIPF0000900 mir-1538 miRBase:MIPF0000903 mir-1537 miRBase:MIPF0000917 mir-4283 miRBase:MIPF0000919 mir-1228 miRBase:MIPF0000924 mir-2355 miRBase:MIPF0000938 mir-647 miRBase:MIPF0000939 mir-1238 miRBase:MIPF0000941 mir-1268 miRBase:MIPF0000946 mir-2861 miRBase:MIPF0000963 mir-1305 miRBase:MIPF0000965 mir-1252 miRBase:MIPF0000968 mir-3119 miRBase:MIPF0000971 mir-608 miRBase:MIPF0000972 mir-1909 miRBase:MIPF0000973 mir-1469 miRBase:MIPF0000979 mir-921 miRBase:MIPF0000982 mir-1269 miRBase:MIPF0000984 mir-1910 miRBase:MIPF0000987 mir-1257 miRBase:MIPF0000998 mir-3116 miRBase:MIPF0001002 mir-1913 miRBase:MIPF0001015 mir-1260a miRBase:MIPF0001020 mir-1908 miRBase:MIPF0001021 mir-1972 miRBase:MIPF0001025 mir-3199 miRBase:MIPF0001026 mir-3160 miRBase:MIPF0001028 mir-4315 miRBase:MIPF0001033 mir-1200 miRBase:MIPF0001036 mir-1915 miRBase:MIPF0001037 mir-1914 miRBase:MIPF0001040 mir-1304 miRBase:MIPF0001064 mir-3158 miRBase:MIPF0001065 mir-1471 miRBase:MIPF0001069 mir-3150 miRBase:MIPF0001102 mir-3074 miRBase:MIPF0001103 mir-3065 miRBase:MIPF0001105 mir-3926 miRBase:MIPF0001118 mir-3913 miRBase:MIPF0001134 mir-3689 miRBase:MIPF0001144 mir-3910 miRBase:MIPF0001148 mir-3914 miRBase:MIPF0001169 mir-3622 miRBase:MIPF0001179 mir-1343 miRBase:MIPF0001206 mir-4509 miRBase:MIPF0001207 mir-4776 miRBase:MIPF0001210 mir-3198 miRBase:MIPF0001216 mir-3135 miRBase:MIPF0001219 mir-4435 miRBase:MIPF0001220 mir-4679 miRBase:MIPF0001228 mir-4650 miRBase:MIPF0001234 mir-4436 miRBase:MIPF0001236 mir-3064 miRBase:MIPF0001238 mir-3155 miRBase:MIPF0001242 mir-4662 miRBase:MIPF0001245 mir-4773 miRBase:MIPF0001250 mir-3190 miRBase:MIPF0001251 mir-4659 miRBase:MIPF0001256 mir-4771 miRBase:MIPF0001258 mir-3529 miRBase:MIPF0001261 mir-3688 miRBase:MIPF0001263 mir-3960 miRBase:MIPF0001271 mir-4520 miRBase:MIPF0001272 mir-4477 miRBase:MIPF0001274 mir-1231 miRBase:MIPF0001309 mir-4444 miRBase:MIPF0001310 mir-4536 miRBase:MIPF0001319 mir-5701 miRBase:MIPF0001325 mir-4524 miRBase:MIPF0001330 mir-3680 miRBase:MIPF0001338 mir-3670 miRBase:MIPF0001340 mir-5681 miRBase:MIPF0001343 mir-5692 miRBase:MIPF0001351 mir-5583 miRBase:MIPF0001356 mir-1260b miRBase:MIPF0001381 mir-6511 miRBase:MIPF0001382 mir-3173 miRBase:MIPF0001383 mir-4743 miRBase:MIPF0001384 mir-4446 miRBase:MIPF0001385 mir-3154 miRBase:MIPF0001387 mir-4667 miRBase:MIPF0001390 mir-3151 miRBase:MIPF0001394 mir-3660 miRBase:MIPF0001397 mir-2110 miRBase:MIPF0001399 mir-3943 miRBase:MIPF0001400 mir-3193 miRBase:MIPF0001401 mir-4796 miRBase:MIPF0001402 mir-6127 miRBase:MIPF0001405 mir-3613 miRBase:MIPF0001411 mir-6131 miRBase:MIPF0001412 mir-6130 miRBase:MIPF0001413 mir-6133 miRBase:MIPF0001415 mir-3121 miRBase:MIPF0001417 mir-6129 miRBase:MIPF0001423 mir-3145 miRBase:MIPF0001427 mir-3138 miRBase:MIPF0001428 mir-23c miRBase:MIPF0001429 mir-6132 miRBase:MIPF0001438 mir-3127 miRBase:MIPF0001439 mir-4484 miRBase:MIPF0001440 mir-3200 miRBase:MIPF0001441 mir-6128 miRBase:MIPF0001442 mir-6134 miRBase:MIPF0001445 mir-4529 miRBase:MIPF0001451 mir-3129 miRBase:MIPF0001458 mir-4660 miRBase:MIPF0001460 mir-3927 miRBase:MIPF0001462 mir-378_2 miRBase:MIPF0001463 mir-2114 miRBase:MIPF0001464 mir-4510 miRBase:MIPF0001467 mir-4429 miRBase:MIPF0001474 mir-4716 miRBase:MIPF0001476 mir-3617 miRBase:MIPF0001477 mir-1273c miRBase:MIPF0001481 mir-3188 miRBase:MIPF0001488 mir-3937 miRBase:MIPF0001500 mir-3117 miRBase:MIPF0001506 mir-4654 miRBase:MIPF0001507 mir-4504 miRBase:MIPF0001508 mir-3132 miRBase:MIPF0001509 mir-6089 miRBase:MIPF0001510 mir-4803 miRBase:MIPF0001511 mir-4515 miRBase:MIPF0001512 mir-3664 miRBase:MIPF0001518 mir-3612 miRBase:MIPF0001519 mir-3938 miRBase:MIPF0001520 mir-4738 miRBase:MIPF0001521 mir-2278 miRBase:MIPF0001522 mir-3126 miRBase:MIPF0001525 mir-3923 miRBase:MIPF0001527 mir-4791 miRBase:MIPF0001529 mir-3661 miRBase:MIPF0001530 mir-3615 miRBase:MIPF0001540 mir-4526 miRBase:MIPF0001545 mir-4782 miRBase:MIPF0001546 mir-4421 miRBase:MIPF0001548 mir-3122 miRBase:MIPF0001549 mir-4672 miRBase:MIPF0001551 mir-4742 miRBase:MIPF0001552 mir-629 miRBase:MIPF0001555 mir-3607 miRBase:MIPF0001566 mir-3174 miRBase:MIPF0001569 mir-4788 miRBase:MIPF0001573 mir-4798 miRBase:MIPF0001574 mir-3136 miRBase:MIPF0001575 mir-4774 miRBase:MIPF0001578 mir-4451 miRBase:MIPF0001582 mir-3934 miRBase:MIPF0001584 mir-4637 miRBase:MIPF0001586 mir-4423 miRBase:MIPF0001587 mir-3192 miRBase:MIPF0001597 mir-3940 miRBase:MIPF0001599 mir-3912 miRBase:MIPF0001601 mir-2392 miRBase:MIPF0001614 mir-3140 miRBase:MIPF0001615 mir-3690 miRBase:MIPF0001618 mir-4488 miRBase:MIPF0001623 mir-3146 miRBase:MIPF0001626 mir-4428 miRBase:MIPF0001630 mir-1976 miRBase:MIPF0001633 mir-3165 miRBase:MIPF0001635 mir-3170 miRBase:MIPF0001637 mir-3605 miRBase:MIPF0001639 mir-4427 miRBase:MIPF0001640 mir-1199 miRBase:MIPF0001659 mir-6516 miRBase:MIPF0001672 mir-6770 miRBase:MIPF0001692 mir-7973 miRBase:MIPF0001693 mir-6859 miRBase:MIPF0001698 mir-6715 miRBase:MIPF0001708 mir-3618 miRBase:MIPF0001710 mir-6794 miRBase:MIPF0001726 mir-6827 miRBase:MIPF0001747 mir-5697 miRBase:MIPF0001748 mir-4703 miRBase:MIPF0001759 mir-4766 miRBase:MIPF0001764 mir-1911 miRBase:MIPF0001787 mir-8071 miRBase:MIPF0001799 mir-6505 miRBase:MIPF0001805 mir-6790 miRBase:MIPF0001811 mir-1243 miRBase:MIPF0001821 mir-3167 miRBase:MIPF0001823 mir-7641 miRBase:MIPF0001825 mir-4433 miRBase:MIPF0001826 mir-4677 miRBase:MIPF0001848 mir-6862 miRBase:MIPF0001855 mir-6724 miRBase:MIPF0001920 mir-3118 miRBase:MIPF0001928 mir-3149 miRBase:MIPF0001935 mir-1277 miRBase:MIPF0001937 mir-3648 miRBase:MIPF0001984 mir-4680 miRBase:MIPF0001988 mir-4657 miRBase:MIPF0002009 mir-8069 miRBase:MIPF0002050 mir-3687 miRBase:MIPF0002051 mir-4449 miRBase:MIPF0002103 mir-4523 miRBase:MIPF0002104 hsa-miR-125b-5p miRBase:MIMAT0000423 hsa-miR-125b-1-3p miRBase:MIMAT0004592 hsa-miR-125b-2-3p miRBase:MIMAT0004603 non-coding RNA A non-coding RNA (ncRNA) is an RNA molecule that is not translated into a protein. Alan Ruttenberg WEB:https://en.wikipedia.org/w/index.php?title=Non-coding_RNA&oldid=688555892#Non-coding RNA ncRNA genetic non-coding RNA A genetic non-coding RNA is a non-coding RNA that is created by transcription in a cell Alan Ruttenberg TODO: Add axiom linking GO transcription synthesized non-coding RNA Alan Ruttenberg TODO: Add axiom relating to OBI planned process and anything else from OBI that is relevant a RNA that is manufactured in a planned process long non-coding RNA Alan Ruttenberg Long non-coding RNAs (long ncRNAs, lncRNA) are non-protein coding transcripts longer than 200 nucleotides. Should requested and then imported from ChEBI This somewhat arbitrary limit distinguishes long ncRNAs from small regulatory RNAs such as microRNAs (miRNAs), short interfering RNAs (siRNAs), Piwi-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs), and other short RNAs WEB:https://en.wikipedia.org/w/index.php?title=Long_non-coding_RNA&oldid=687562040#Long non-coding RNA lncRNA small interfering RNA Alan Ruttenberg Should requested and then imported from ChEBI WEB:https://en.wikipedia.org/w/index.php?title=Special:CiteThisPage&page=Small_interfering_RNA&id=685334024#Small_interfering_RNA siRNA small interfering RNA (siRNA) is a class of double-stranded RNA molecules, 20-25 base pairs in length. siRNA plays many roles, but it is most notable in the RNA interference (RNAi) pathway, where it interferes with thes expression of specific genes with complementary nucleotide sequences. Removed axiom 'derives_from some miRNA_primary_transcript' pending review of status of SO terms. Changed relation of small regulatory ncRNA (superclass) into is about relationship