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xmlns:owl="http://www.w3.org/2002/07/owl#"
xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
xmlns:xml="http://www.w3.org/XML/1998/namespace"
xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
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xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
xmlns:swrl="http://www.w3.org/2003/11/swrl#"
xmlns:swrlb="http://www.w3.org/2003/11/swrlb#"
xmlns:terms="http://purl.org/dc/terms/"
xmlns:protege="http://protege.stanford.edu/plugins/owl/protege#"
xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#">
<owl:Ontology rdf:about="http://purl.obolibrary.org/obo/obi.owl">
<owl:versionIRI rdf:resource="http://purl.obolibrary.org/obo/obi/2025-03-06/obi.owl"/>
<protege:defaultLanguage>en</protege:defaultLanguage>
<obo:IAO_0000589 xml:lang="en">Ontology for Biomedical Investigations</obo:IAO_0000589>
<dc:contributor xml:lang="en">Advisors for this project come from the IFOMIS group, Saarbruecken and from the Co-ODE group in Manchester</dc:contributor>
<dc:creator xml:lang="en">Alan Ruttenberg</dc:creator>
<dc:creator xml:lang="en">Allyson Lister</dc:creator>
<dc:creator xml:lang="en">Barry Smith</dc:creator>
<dc:creator xml:lang="en">Bill Bug</dc:creator>
<dc:creator xml:lang="en">Bjoern Peters</dc:creator>
<dc:creator xml:lang="en">Carlo Torniai</dc:creator>
<dc:creator xml:lang="en">Chris Mungall</dc:creator>
<dc:creator xml:lang="en">Chris Stoeckert</dc:creator>
<dc:creator xml:lang="en">Chris Taylor</dc:creator>
<dc:creator xml:lang="en">Christian Bolling</dc:creator>
<dc:creator xml:lang="en">Cristian Cocos</dc:creator>
<dc:creator xml:lang="en">Daniel Rubin</dc:creator>
<dc:creator xml:lang="en">Daniel Schober</dc:creator>
<dc:creator xml:lang="en">Dawn Field</dc:creator>
<dc:creator xml:lang="en">Dirk Derom</dc:creator>
<dc:creator xml:lang="en">Elisabetta Manduchi</dc:creator>
<dc:creator xml:lang="en">Eric Deutsch</dc:creator>
<dc:creator xml:lang="en">Frank Gibson</dc:creator>
<dc:creator xml:lang="en">Gilberto Fragoso</dc:creator>
<dc:creator xml:lang="en">Helen C. Causton</dc:creator>
<dc:creator xml:lang="en">Helen Parkinson</dc:creator>
<dc:creator xml:lang="en">Holger Stenzhorn</dc:creator>
<dc:creator xml:lang="en">James A. Overton</dc:creator>
<dc:creator xml:lang="en">James Malone</dc:creator>
<dc:creator xml:lang="en">Jay Greenbaum</dc:creator>
<dc:creator xml:lang="en">Jeffrey Grethe</dc:creator>
<dc:creator xml:lang="en">Jennifer Fostel</dc:creator>
<dc:creator xml:lang="en">Jessica Turner</dc:creator>
<dc:creator xml:lang="en">Jie Zheng</dc:creator>
<dc:creator xml:lang="en">Joe White</dc:creator>
<dc:creator xml:lang="en">John Westbrook</dc:creator>
<dc:creator xml:lang="en">Kevin Clancy</dc:creator>
<dc:creator xml:lang="en">Larisa Soldatova</dc:creator>
<dc:creator xml:lang="en">Lawrence Hunter</dc:creator>
<dc:creator xml:lang="en">Liju Fan</dc:creator>
<dc:creator xml:lang="en">Luisa Montecchi</dc:creator>
<dc:creator xml:lang="en">Matthew Brush</dc:creator>
<dc:creator xml:lang="en">Matthew Pocock</dc:creator>
<dc:creator xml:lang="en">Melanie Courtot</dc:creator>
<dc:creator xml:lang="en">Melissa Haendel</dc:creator>
<dc:creator xml:lang="en">Mervi Heiskanen</dc:creator>
<dc:creator xml:lang="en">Monnie McGee</dc:creator>
<dc:creator xml:lang="en">Norman Morrison</dc:creator>
<dc:creator xml:lang="en">Philippe Rocca-Serra</dc:creator>
<dc:creator xml:lang="en">Phillip Lord</dc:creator>
<dc:creator xml:lang="en">Pierre Grenon</dc:creator>
<dc:creator xml:lang="en">Richard Bruskiewich</dc:creator>
<dc:creator xml:lang="en">Richard Scheuermann</dc:creator>
<dc:creator xml:lang="en">Robert Stevens</dc:creator>
<dc:creator xml:lang="en">Ryan R. Brinkman</dc:creator>
<dc:creator xml:lang="en">Stefan Wiemann</dc:creator>
<dc:creator xml:lang="en">Susanna-Assunta Sansone</dc:creator>
<dc:creator xml:lang="en">Tanya Gray</dc:creator>
<dc:creator xml:lang="en">Tina Hernandez-Boussard</dc:creator>
<dc:creator xml:lang="en">Trish Whetzel</dc:creator>
<dc:creator xml:lang="en">Yongqun He</dc:creator>
<dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2009-07-31</dc:date>
<dc:description xml:lang="en">An ontology for representing biomedical investigations, including study designs, the collection and preparation of the targets of investigation, assays, instrumentation and reagents used, as well as the data generated and the types of analysis performed on the data to reach conclusions, and their documentation.</dc:description>
<dc:format xml:lang="en">OWL-DL</dc:format>
<dc:subject xml:lang="en">An ontology for the annotation of biomedical and functional genomics experiments.</dc:subject>
<terms:license>http://creativecommons.org/licenses/by/4.0/</terms:license>
<terms:title>Ontology for Biomedical Investigations</terms:title>
<rdfs:comment>Please cite the OBI consortium http://purl.obolibrary.org/obo/obi where traditional citation is called for. However it is adequate that individual terms be attributed simply by use of the identifying PURL for the term, in projects that refer to them.</rdfs:comment>
<owl:versionInfo>2025-03-06</owl:versionInfo>
</owl:Ontology>
<!--
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//
// Annotation properties
//
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<!-- http://protege.stanford.edu/plugins/owl/protege#defaultLanguage -->
<owl:AnnotationProperty rdf:about="http://protege.stanford.edu/plugins/owl/protege#defaultLanguage"/>
<!-- http://purl.obolibrary.org/obo/BFO_0000179 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000179">
<obo:IAO_0000115 xml:lang="en">Relates an entity in the ontology to the name of the variable that is used to represent it in the code that generates the BFO OWL file from the lispy specification.</obo:IAO_0000115>
<obo:IAO_0000232 xml:lang="en">Really of interest to developers only</obo:IAO_0000232>
<rdfs:label xml:lang="en">BFO OWL specification label</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://www.w3.org/2000/01/rdf-schema#label"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/BFO_0000180 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000180">
<obo:IAO_0000115 xml:lang="en">Relates an entity in the ontology to the term that is used to represent it in the the CLIF specification of BFO2</obo:IAO_0000115>
<obo:IAO_0000119>Person:Alan Ruttenberg</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">Really of interest to developers only</obo:IAO_0000232>
<rdfs:label xml:lang="en">BFO CLIF specification label</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://www.w3.org/2000/01/rdf-schema#label"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0000111 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000111">
<obo:IAO_0000111 xml:lang="en">editor preferred label</obo:IAO_0000111>
<obo:IAO_0000111>editor preferred term</obo:IAO_0000111>
<obo:IAO_0000111 xml:lang="en">editor preferred term</obo:IAO_0000111>
<obo:IAO_0000111>editor preferred term~editor preferred label</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">The concise, meaningful, and human-friendly name for a class or property preferred by the ontology developers. (US-English)</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">GROUP:OBI:<http://purl.obolibrary.org/obo/obi></obo:IAO_0000119>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">editor preferred label</rdfs:label>
<rdfs:label>editor preferred term</rdfs:label>
<rdfs:label xml:lang="en">editor preferred term</rdfs:label>
<rdfs:label>editor preferred term~editor preferred label</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0000112 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000112">
<obo:IAO_0000111 xml:lang="en">example of usage</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A phrase describing how a term should be used and/or a citation to a work which uses it. May also include other kinds of examples that facilitate immediate understanding, such as widely know prototypes or instances of a class, or cases where a relation is said to hold.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">GROUP:OBI:<http://purl.obolibrary.org/obo/obi></obo:IAO_0000119>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">example of usage</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0000113 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000113">
<obo:IAO_0000111 xml:lang="en">in branch</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">An annotation property indicating which module the terms belong to. This is currently experimental and not implemented yet.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">GROUP:OBI</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI_0000277</obo:IAO_0000119>
<rdfs:label xml:lang="en">in branch</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0000114 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000114">
<obo:IAO_0000111 xml:lang="en">has curation status</obo:IAO_0000111>
<obo:IAO_0000117 xml:lang="en">PERSON:Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">PERSON:Bill Bug</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">PERSON:Melanie Courtot</obo:IAO_0000117>
<rdfs:label xml:lang="en">has curation status</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0000115 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115">
<obo:IAO_0000111>definition</obo:IAO_0000111>
<obo:IAO_0000111 xml:lang="en">definition</obo:IAO_0000111>
<obo:IAO_0000111>textual definition</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">The official OBI definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions.</obo:IAO_0000115>
<obo:IAO_0000115 xml:lang="en">The official definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">2012-04-05:
Barry Smith
The official OBI definition, explaining the meaning of a class or property: 'Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions' is terrible.
Can you fix to something like:
A statement of necessary and sufficient conditions explaining the meaning of an expression referring to a class or property.
Alan Ruttenberg
Your proposed definition is a reasonable candidate, except that it is very common that necessary and sufficient conditions are not given. Mostly they are necessary, occasionally they are necessary and sufficient or just sufficient. Often they use terms that are not themselves defined and so they effectively can't be evaluated by those criteria.
On the specifics of the proposed definition:
We don't have definitions of 'meaning' or 'expression' or 'property'. For 'reference' in the intended sense I think we use the term 'denotation'. For 'expression', I think we you mean symbol, or identifier. For 'meaning' it differs for class and property. For class we want documentation that let's the intended reader determine whether an entity is instance of the class, or not. For property we want documentation that let's the intended reader determine, given a pair of potential relata, whether the assertion that the relation holds is true. The 'intended reader' part suggests that we also specify who, we expect, would be able to understand the definition, and also generalizes over human and computer reader to include textual and logical definition.
Personally, I am more comfortable weakening definition to documentation, with instructions as to what is desirable.
We also have the outstanding issue of how to aim different definitions to different audiences. A clinical audience reading chebi wants a different sort of definition documentation/definition from a chemistry trained audience, and similarly there is a need for a definition that is adequate for an ontologist to work with.</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">GROUP:OBI:<http://purl.obolibrary.org/obo/obi></obo:IAO_0000119>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label>definition</rdfs:label>
<rdfs:label xml:lang="en">definition</rdfs:label>
<rdfs:label>textual definition</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0000116 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000116">
<obo:IAO_0000111 xml:lang="en">editor note</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An administrative note intended for its editor. It may not be included in the publication version of the ontology, so it should contain nothing necessary for end users to understand the ontology.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">GROUP:OBI:<http://purl.obofoundry.org/obo/obi></obo:IAO_0000119>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">editor note</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0000117 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000117">
<obo:IAO_0000111 xml:lang="en">term editor</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">Name of editor entering the term in the file. The term editor is a point of contact for information regarding the term. The term editor may be, but is not always, the author of the definition, which may have been worked upon by several people</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">20110707, MC: label update to term editor and definition modified accordingly. See https://github.com/information-artifact-ontology/IAO/issues/115.</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">GROUP:OBI:<http://purl.obolibrary.org/obo/obi></obo:IAO_0000119>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">term editor</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0000118 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000118">
<obo:IAO_0000111 xml:lang="en">alternative label</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A label for a class or property that can be used to refer to the class or property instead of the preferred rdfs:label. Alternative labels should be used to indicate community- or context-specific labels, abbreviations, shorthand forms and the like.</obo:IAO_0000115>
<obo:IAO_0000117>OBO Operations committee</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">GROUP:OBI:<http://purl.obolibrary.org/obo/obi></obo:IAO_0000119>
<rdfs:comment>Consider re-defing to: An alternative name for a class or property which can mean the same thing as the preferred name (semantically equivalent, narrow, broad or related).</rdfs:comment>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">alternative label</rdfs:label>
<rdfs:label xml:lang="en">alternative term</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0000119 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000119">
<obo:IAO_0000111 xml:lang="en">definition source</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">Formal citation, e.g. identifier in external database to indicate / attribute source(s) for the definition. Free text indicate / attribute source(s) for the definition. EXAMPLE: Author Name, URI, MeSH Term C04, PUBMED ID, Wiki uri on 31.01.2007</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">Discussion on obo-discuss mailing-list, see http://bit.ly/hgm99w</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">GROUP:OBI:<http://purl.obolibrary.org/obo/obi></obo:IAO_0000119>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">definition source</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0000231 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000231">
<obo:IAO_0000111 xml:lang="en">has obsolescence reason</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">Relates an annotation property to an obsolescence reason. The values of obsolescence reasons come from a list of predefined terms, instances of the class obsolescence reason specification.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON:Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">PERSON:Melanie Courtot</obo:IAO_0000117>
<rdfs:label xml:lang="en">has obsolescence reason</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0000232 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000232">
<obo:IAO_0000111 xml:lang="en">curator note</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An administrative note of use for a curator but of no use for a user</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON:Alan Ruttenberg</obo:IAO_0000117>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">curator note</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0000233 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000233">
<obo:IAO_0000111 xml:lang="en">term tracker item</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">the URI for an OBI Terms ticket at sourceforge, such as https://sourceforge.net/p/obi/obi-terms/772/</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">An IRI or similar locator for a request or discussion of an ontology term.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg</obo:IAO_0000119>
<rdfs:comment xml:lang="en">The 'tracker item' can associate a tracker with a specific ontology term.</rdfs:comment>
<rdfs:label xml:lang="en">term tracker item</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0000234 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000234">
<obo:IAO_0000111 xml:lang="en">ontology term requester</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">The name of the person, project, or organization that motivated inclusion of an ontology term by requesting its addition.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg</obo:IAO_0000119>
<rdfs:comment>The 'term requester' can credit the person, organization or project who request the ontology term.</rdfs:comment>
<rdfs:label xml:lang="en">ontology term requester</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0000411 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000411">
<obo:IAO_0000111 xml:lang="en">is denotator type</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">Relates an class defined in an ontology, to the type of it's denotator</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">In OWL 2 add AnnotationPropertyRange('is denotator type' 'denotator type')</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Alan Ruttenberg</obo:IAO_0000117>
<rdfs:label xml:lang="en">is denotator type</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0000412 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000412">
<obo:IAO_0000111 xml:lang="en">imported from</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">For external terms/classes, the ontology from which the term was imported</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON:Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">PERSON:Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">GROUP:OBI:<http://purl.obolibrary.org/obo/obi></obo:IAO_0000119>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">imported from</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0000424 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000424">
<obo:IAO_0000111 xml:lang="en">expand expression to</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">ObjectProperty: RO_0002104
Label: has plasma membrane part
Annotations: IAO_0000424 "http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.org/obo/owl/GO#GO_0005886 and http://purl.obolibrary.org/obo/BFO_0000051 some ?Y)"
</obo:IAO_0000112>
<obo:IAO_0000115 xml:lang="en">A macro expansion tag applied to an object property (or possibly a data property) which can be used by a macro-expansion engine to generate more complex expressions from simpler ones</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<rdfs:label xml:lang="en">expand expression to</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0000425 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000425">
<obo:IAO_0000111 xml:lang="en">expand assertion to</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">ObjectProperty: RO???
Label: spatially disjoint from
Annotations: expand_assertion_to "DisjointClasses: (http://purl.obolibrary.org/obo/BFO_0000051 some ?X) (http://purl.obolibrary.org/obo/BFO_0000051 some ?Y)"
</obo:IAO_0000112>
<obo:IAO_0000115 xml:lang="en">A macro expansion tag applied to an annotation property which can be expanded into a more detailed axiom.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<rdfs:label xml:lang="en">expand assertion to</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0000426 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000426">
<obo:IAO_0000111 xml:lang="en">first order logic expression</obo:IAO_0000111>
<obo:IAO_0000117 xml:lang="en">PERSON:Alan Ruttenberg</obo:IAO_0000117>
<rdfs:label xml:lang="en">first order logic expression</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0000427 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000427">
<obo:IAO_0000111 xml:lang="en">antisymmetric property</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">part_of antisymmetric property xsd:true</obo:IAO_0000112>
<obo:IAO_0000115 xml:lang="en">Use boolean value xsd:true to indicate that the property is an antisymmetric property</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Alan Ruttenberg</obo:IAO_0000117>
<rdfs:label xml:lang="en">antisymmetric property</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/OMO_0001001"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0000589 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000589">
<obo:IAO_0000111 xml:lang="en">OBO foundry unique label</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">An alternative name for a class or property which is unique across the OBO Foundry.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">The intended usage of that property is as follow: OBO foundry unique labels are automatically generated based on regular expressions provided by each ontology, so that SO could specify unique label = 'sequence ' + [label], etc. , MA could specify 'mouse + [label]' etc. Upon importing terms, ontology developers can choose to use the 'OBO foundry unique label' for an imported term or not. The same applies to tools .</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">PERSON:Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">PERSON:Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">PERSON:Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">PERSON:Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">GROUP:OBO Foundry <http://obofoundry.org/></obo:IAO_0000119>
<rdfs:label xml:lang="en">OBO foundry unique label</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0000596 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000596">
<obo:IAO_0000111 xml:lang="en">has ID digit count</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Ontology: <http://purl.obolibrary.org/obo/ro/idrange/>
Annotations:
'has ID prefix': "http://purl.obolibrary.org/obo/RO_"
'has ID digit count' : 7,
rdfs:label "RO id policy"
'has ID policy for': "RO"</obo:IAO_0000112>
<obo:IAO_0000115 xml:lang="en">Relates an ontology used to record id policy to the number of digits in the URI. The URI is: the 'has ID prefix" annotation property value concatenated with an integer in the id range (left padded with "0"s to make this many digits)</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000117>
<rdfs:label xml:lang="en">has ID digit count</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0000597 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000597">
<obo:IAO_0000111 xml:lang="en">has ID range allocated</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Datatype: idrange:1
Annotations: 'has ID range allocated to': "Chris Mungall"
EquivalentTo: xsd:integer[> 2151 , <= 2300]
</obo:IAO_0000112>
<obo:IAO_0000115 xml:lang="en">Relates a datatype that encodes a range of integers to the name of the person or organization who can use those ids constructed in that range to define new terms</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000117>
<rdfs:label xml:lang="en">has ID range allocated to</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0000598 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000598">
<obo:IAO_0000111 xml:lang="en">has ID policy for</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Ontology: <http://purl.obolibrary.org/obo/ro/idrange/>
Annotations:
'has ID prefix': "http://purl.obolibrary.org/obo/RO_"
'has ID digit count' : 7,
rdfs:label "RO id policy"
'has ID policy for': "RO"</obo:IAO_0000112>
<obo:IAO_0000115 xml:lang="en">Relating an ontology used to record id policy to the ontology namespace whose policy it manages</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000117>
<rdfs:label xml:lang="en">has ID policy for</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0000599 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000599">
<obo:IAO_0000111 xml:lang="en">has ID prefix</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Ontology: <http://purl.obolibrary.org/obo/ro/idrange/>
Annotations:
'has ID prefix': "http://purl.obolibrary.org/obo/RO_"
'has ID digit count' : 7,
rdfs:label "RO id policy"
'has ID policy for': "RO"</obo:IAO_0000112>
<obo:IAO_0000115 xml:lang="en">Relates an ontology used to record id policy to a prefix concatenated with an integer in the id range (left padded with "0"s to make this many digits) to construct an ID for a term being created.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000117>
<rdfs:label xml:lang="en">has ID prefix</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0000600 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000600">
<obo:IAO_0000111 xml:lang="en">elucidation</obo:IAO_0000111>
<obo:IAO_0000117 xml:lang="en">person:Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">Person:Barry Smith</obo:IAO_0000119>
<obo:IAO_0000600 xml:lang="en">Primitive terms in a highest-level ontology such as BFO are terms which are so basic to our understanding of reality that there is no way of defining them in a non-circular fashion. For these, therefore, we can provide only elucidations, supplemented by examples and by axioms</obo:IAO_0000600>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">elucidation</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0000601 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000601">
<obo:IAO_0000111 xml:lang="en">has associated axiom(nl)</obo:IAO_0000111>
<obo:IAO_0000117 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000119>
<obo:IAO_0000600 xml:lang="en">An axiom associated with a term expressed using natural language</obo:IAO_0000600>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">has associated axiom(nl)</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0000602 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000602">
<obo:IAO_0000111 xml:lang="en">has associated axiom(fol)</obo:IAO_0000111>
<obo:IAO_0000117 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000119>
<obo:IAO_0000600 xml:lang="en">An axiom expressed in first order logic using CLIF syntax</obo:IAO_0000600>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">has associated axiom(fol)</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0000603 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000603">
<obo:IAO_0000111 xml:lang="en">is allocated id range</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">Relates an ontology IRI to an (inclusive) range of IRIs in an OBO name space. The range is give as, e.g. "IAO_0020000-IAO_0020999"</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON:Alan Ruttenberg</obo:IAO_0000117>
<rdfs:comment xml:lang="en">Add as annotation triples in the granting ontology</rdfs:comment>
<rdfs:label xml:lang="en">is allocated id range</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0000700 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000700">
<obo:IAO_0000111 xml:lang="en">has ontology root term</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">Ontology annotation property. Relates an ontology to a term that is a designated root term of the ontology. Display tools like OLS can use terms annotated with this property as the starting point for rendering the ontology class hierarchy. There can be more than one root.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Nicolas Matentzoglu</obo:IAO_0000117>
<rdfs:label xml:lang="en">has ontology root term</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0006011 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0006011">
<obo:IAO_0000111 xml:lang="en">may be identical to</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A annotation relationship between two terms in an ontology that may refer to the same (natural) type but where more evidence is required before terms are merged.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000233 xml:lang="en">#40</obo:IAO_0000233>
<obo:IAO_0000234 xml:lang="en">VFB</obo:IAO_0000234>
<rdfs:comment xml:lang="en">Edges asserting this should be annotated with to record evidence supporting the assertion and its provenance.</rdfs:comment>
<rdfs:label xml:lang="en">may be identical to</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0006012 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0006012">
<obo:IAO_0000111 xml:lang="en">scheduled for obsoletion on or after</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">Used when the class or object is scheduled for obsoletion/deprecation on or after a particular date.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Chris Mungall, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000233 xml:lang="en">https://github.com/geneontology/go-ontology/issues/15532</obo:IAO_0000233>
<obo:IAO_0000233 xml:lang="en">https://github.com/information-artifact-ontology/ontology-metadata/issues/32</obo:IAO_0000233>
<obo:IAO_0000234 xml:lang="en">GO ontology</obo:IAO_0000234>
<rdfs:label xml:lang="en">scheduled for obsoletion on or after</rdfs:label>
<rdfs:range rdf:resource="http://www.w3.org/2001/XMLSchema#dateTime"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0010000 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0010000">
<obo:IAO_0000111 xml:lang="en">has axiom id</obo:IAO_0000111>
<obo:IAO_0000117 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000119>
<obo:IAO_0000600 xml:lang="en">A URI that is intended to be unique label for an axiom used for tracking change to the ontology. For an axiom expressed in different languages, each expression is given the same URI</obo:IAO_0000600>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">has axiom label</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0100001 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0100001">
<obo:IAO_0000111 xml:lang="en">term replaced by</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">Use on obsolete terms, relating the term to another term that can be used as a substitute</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000119>
<rdfs:comment xml:lang="en">Add as annotation triples in the granting ontology</rdfs:comment>
<rdfs:label xml:lang="en">term replaced by</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0001847 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0001847">
<obo:IAO_0000111 xml:lang="en">ISA alternative term</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An alternative term used by the ISA tools project (http://isa-tools.org).</obo:IAO_0000115>
<obo:IAO_0000116>Requested by Alejandra Gonzalez-Beltran
https://sourceforge.net/tracker/?func=detail&aid=3603413&group_id=177891&atid=886178</obo:IAO_0000116>
<obo:IAO_0000117>Person: Alejandra Gonzalez-Beltran</obo:IAO_0000117>
<obo:IAO_0000117>Person: Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>ISA tools project (http://isa-tools.org)</obo:IAO_0000119>
<rdfs:label xml:lang="en">ISA alternative term</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000118"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0001886 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0001886">
<obo:IAO_0000111 xml:lang="en">NIAID GSCID-BRC alternative term</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An alternative term used by the National Institute of Allergy and Infectious Diseases (NIAID) Genomic Sequencing Centers for Infectious Diseases (GSCID) and Bioinformatics Resource Centers (BRC).</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<rdfs:label xml:lang="en">NIAID GSCID-BRC alternative term</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000118"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/OBI_9991118 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OBI_9991118">
<obo:IAO_0000111>IEDB alternative term</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An alternative term used by the IEDB.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>IEDB alternative term</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000118"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/OBI_9991119 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OBI_9991119">
<obo:IAO_0000111>FGED alternative term</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An alternative term used by the Functional Genomics Data (FGED) Society.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>Penn Group</obo:IAO_0000119>
<rdfs:label>FGED alternative term</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000118"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/OMO_0001001 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OMO_0001001">
<obo:IAO_0000115>This is an annotation used on an object property to indicate a logical characterstic beyond what is possible in OWL.</obo:IAO_0000115>
<obo:IAO_0000119>OBO Operations call</obo:IAO_0000119>
<oboInOwl:created_by rdf:resource="http://orcid.org/0000-0001-5208-3432"/>
<rdfs:label>logical characteristic of object property</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/OMO_0002000 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OMO_0002000">
<obo:IAO_0000112>'part disjoint with' 'defined by construct' """
PREFIX owl: <http://www.w3.org/2002/07/owl#>
PREFIX : <http://example.org/
CONSTRUCT {
[
a owl:Restriction ;
owl:onProperty :part_of ;
owl:someValuesFrom ?a ;
owl:disjointWith [
a owl:Restriction ;
owl:onProperty :part_of ;
owl:someValuesFrom ?b
]
]
}
WHERE {
?a :part_disjoint_with ?b .
}</obo:IAO_0000112>
<obo:IAO_0000115>Links an annotation property to a SPARQL CONSTRUCT query which is meant to provide semantics for a shortcut relation.</obo:IAO_0000115>
<obo:IAO_0000233 rdf:resource="https://github.com/ontodev/robot/issues/963"/>
<dc:contributor rdf:resource="https://orcid.org/0000-0002-7356-1779"/>
<dc:contributor rdf:resource="https://orcid.org/0000-0002-8688-6599"/>
<rdfs:label>defined by construct</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/OMO_0003000 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OMO_0003000">
<obo:IAO_0000112>CHEBI:26523 (reactive oxygen species) has an exact synonym (ROS), which is of type OMO:0003000 (abbreviation)</obo:IAO_0000112>
<obo:IAO_0000115>A synonym type for describing abbreviations or initalisms</obo:IAO_0000115>
<obo:IAO_0000233 rdf:resource="https://github.com/information-artifact-ontology/ontology-metadata/issues/122"/>
<terms:contributor rdf:resource="https://orcid.org/0000-0003-4423-4370"/>
<terms:created rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2023-03-03</terms:created>
<rdfs:label>abbreviation</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/OMO_0003001 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OMO_0003001">
<obo:IAO_0000115>A synonym type for describing ambiguous synonyms</obo:IAO_0000115>
<obo:IAO_0000233 rdf:resource="https://github.com/information-artifact-ontology/ontology-metadata/issues/122"/>
<terms:contributor rdf:resource="https://orcid.org/0000-0003-4423-4370"/>
<terms:created rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2023-03-03</terms:created>
<rdfs:label>ambiguous synonym</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/OMO_0003002 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OMO_0003002">
<obo:IAO_0000115>A synonym type for describing dubious synonyms</obo:IAO_0000115>
<obo:IAO_0000233 rdf:resource="https://github.com/information-artifact-ontology/ontology-metadata/issues/122"/>
<terms:contributor rdf:resource="https://orcid.org/0000-0003-4423-4370"/>
<terms:created rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2023-03-03</terms:created>
<rdfs:label>dubious synonym</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/OMO_0003003 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OMO_0003003">
<obo:IAO_0000112>EFO:0006346 (severe cutaneous adverse reaction) has an exact synonym (scar), which is of the type OMO:0003003 (layperson synonym)</obo:IAO_0000112>
<obo:IAO_0000115>A synonym type for describing layperson or colloquial synonyms</obo:IAO_0000115>
<obo:IAO_0000233 rdf:resource="https://github.com/information-artifact-ontology/ontology-metadata/issues/122"/>
<terms:contributor rdf:resource="https://orcid.org/0000-0003-4423-4370"/>
<terms:created rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2023-03-03</terms:created>
<rdfs:label>layperson synonym</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/OMO_0003004 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OMO_0003004">
<obo:IAO_0000112>CHEBI:23367 (molecular entity) has an exact synonym (molecular entities), which is of the type OMO:0003004 (plural form)</obo:IAO_0000112>
<obo:IAO_0000115>A synonym type for describing pluralization synonyms</obo:IAO_0000115>
<obo:IAO_0000233 rdf:resource="https://github.com/information-artifact-ontology/ontology-metadata/issues/122"/>
<terms:contributor rdf:resource="https://orcid.org/0000-0003-4423-4370"/>
<terms:created rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2023-03-03</terms:created>
<rdfs:label>plural form</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/OMO_0003005 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OMO_0003005">
<obo:IAO_0000112>CHEBI:16189 (sulfate) has an exact synonym (sulphate), which is of the type OMO:0003005 (UK spelling synonym)</obo:IAO_0000112>
<obo:IAO_0000115>A synonym type for describing UK spelling variants</obo:IAO_0000115>
<obo:IAO_0000233 rdf:resource="https://github.com/information-artifact-ontology/ontology-metadata/issues/122"/>
<terms:contributor rdf:resource="https://orcid.org/0000-0003-4423-4370"/>
<terms:created rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2023-03-03</terms:created>
<rdfs:label>UK spelling synonym</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/OMO_0003006 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OMO_0003006">
<obo:IAO_0000115>A synonym type for common misspellings</obo:IAO_0000115>
<obo:IAO_0000233 rdf:resource="https://github.com/information-artifact-ontology/ontology-metadata/issues/132"/>
<terms:contributor rdf:resource="https://orcid.org/0000-0003-4423-4370"/>
<terms:created rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2023-03-03</terms:created>
<rdfs:label>misspelling</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/OMO_0003007 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OMO_0003007">
<obo:IAO_0000115>A synonym type for misnomers, i.e., a synonym that is not technically correct but is commonly used anyway</obo:IAO_0000115>
<obo:IAO_0000233 rdf:resource="https://github.com/information-artifact-ontology/ontology-metadata/issues/133"/>
<terms:contributor rdf:resource="https://orcid.org/0000-0003-4423-4370"/>
<terms:created rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2023-03-03</terms:created>
<rdfs:label>misnomer</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/OMO_0003008 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OMO_0003008">
<obo:IAO_0000112>MAPT, the gene that encodes the Tau protein, has a previous name DDPAC. Note: in this case, the name type is more specifically the gene symbol.</obo:IAO_0000112>
<obo:IAO_0000115>A synonym type for names that have been used as primary labels in the past.</obo:IAO_0000115>
<obo:IAO_0000233 rdf:resource="https://github.com/information-artifact-ontology/ontology-metadata/issues/139"/>
<terms:contributor rdf:resource="https://orcid.org/0000-0003-4423-4370"/>
<terms:created rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2023-07-25</terms:created>
<rdfs:label>previous name</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/OMO_0003009 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OMO_0003009">
<obo:IAO_0000112>The legal name for Harvard University (https://ror.org/03vek6s52) is President and Fellows of Harvard College</obo:IAO_0000112>
<obo:IAO_0000115>A synonym type for the legal entity name</obo:IAO_0000115>
<obo:IAO_0000233 rdf:resource="https://github.com/information-artifact-ontology/ontology-metadata/issues/141"/>
<terms:contributor rdf:resource="https://orcid.org/0000-0003-4423-4370"/>
<terms:created rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2023-07-27</terms:created>
<rdfs:label>legal name</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/OMO_0003010 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OMO_0003010">
<obo:IAO_0000112>CHEBI:46195 has been assigned the english International Nonproproprietary Name (INN) "paracetamol". In some cases such as this one, the INN might be the same as the ontology's primary label</obo:IAO_0000112>
<obo:IAO_0000115>The International Nonproprietary Name (INN) is a standardize name for a pharmaceutical drug or active ingredient issued by the World Health Organization (WHO) meant to address the issues with country- or language-specific brand names. These are issued in several languages, including English, Latin, French, Russian, Spanish, Arabic, and Chinese.</obo:IAO_0000115>
<obo:IAO_0000233 rdf:resource="https://github.com/information-artifact-ontology/ontology-metadata/issues/149"/>
<terms:contributor rdf:resource="https://orcid.org/0000-0003-4423-4370"/>
<terms:created rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2023-09-30</terms:created>
<oboInOwl:hasExactSynonym>INN</oboInOwl:hasExactSynonym>
<rdfs:label>International Nonproprietary Name</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/OMO_0003011 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OMO_0003011">
<obo:IAO_0000112>nasopharynx (UBERON:0001728) has the latin name "pars nasalis pharyngis</obo:IAO_0000112>
<obo:IAO_0000115>A synonym type for describing Latin term synonyms.</obo:IAO_0000115>
<obo:IAO_0000233 rdf:resource="https://github.com/information-artifact-ontology/ontology-metadata/issues/146"/>
<terms:contributor rdf:resource="https://orcid.org/0000-0002-1773-2692"/>
<terms:created rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2023-10-12</terms:created>
<rdfs:label>latin term</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/OMO_0003012 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OMO_0003012">
<obo:IAO_0000112>NASA is an word acronym for the US National Aeronautics and Space Administration because the acronym is pronounced. FBI is an initialism (also known as alphabetism) for the US Federal Bureau of Investigation since the letters are pronounced one at a time. JPEG is an acronym for Joint Photographic Experts Group but does not count as a word acronym nor an initialism since it is mixed how it is pronounced.</obo:IAO_0000112>
<obo:IAO_0000115>A synonym type for describing abbreviations that are a part of the full name's words, such as initialisms or alphabetisms.</obo:IAO_0000115>
<obo:IAO_0000233 rdf:resource="https://github.com/information-artifact-ontology/ontology-metadata/issues/135"/>
<terms:contributor rdf:resource="https://orcid.org/0000-0003-4423-4370"/>
<terms:created rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2023-11-01</terms:created>
<rdfs:label>acronym</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/OMO_0004000 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OMO_0004000">
<obo:IAO_0000112>A serial number such as "12324X"; a stop sign; a written proper name such as "OBI</obo:IAO_0000112>
<obo:IAO_0000115>An information content entity that is a mark(s) or character(s) used as a conventional representation of another entity.</obo:IAO_0000115>
<obo:IAO_0000233 rdf:resource="https://github.com/information-artifact-ontology/ontology-metadata/issues/144"/>
<terms:contributor rdf:resource="https://orcid.org/0000-0002-6523-4866"/>
<terms:created rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2024-03-25</terms:created>
<rdfs:label>has symbol</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0001900 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0001900"/>
<!-- http://purl.org/dc/elements/1.1/contributor -->
<owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/contributor">
<dc:description xml:lang="en-us">Examples of a Contributor include a person, an
organisation, or a service. Typically, the name of a
Contributor should be used to indicate the entity.</dc:description>
<rdfs:comment xml:lang="en-us">An entity responsible for making contributions to the
content of the resource.</rdfs:comment>
<rdfs:isDefinedBy rdf:resource="http://purl.org/dc/elements/1.1/"/>
<rdfs:label>Contributor</rdfs:label>
<rdfs:label xml:lang="en-us">Contributor</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.org/dc/elements/1.1/coverage -->
<owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/coverage">
<dc:description xml:lang="en-us">Coverage will typically include spatial location (a place name
or geographic coordinates), temporal period (a period label,
date, or date range) or jurisdiction (such as a named
administrative entity).
Recommended best practice is to select a value from a
controlled vocabulary (for example, the Thesaurus of Geographic
Names [TGN]) and that, where appropriate, named places or time
periods be used in preference to numeric identifiers such as
sets of coordinates or date ranges.</dc:description>
<rdfs:comment xml:lang="en-us">The extent or scope of the content of the resource.</rdfs:comment>
<rdfs:isDefinedBy rdf:resource="http://purl.org/dc/elements/1.1/"/>
<rdfs:label>Coverage</rdfs:label>
<rdfs:label xml:lang="en-us">Coverage</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.org/dc/elements/1.1/creator -->
<owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/creator">
<dc:description xml:lang="en-us">Examples of a Creator include a person, an organisation,
or a service. Typically, the name of a Creator should
be used to indicate the entity.</dc:description>
<rdfs:comment xml:lang="en-us">An entity primarily responsible for making the content
of the resource.</rdfs:comment>
<rdfs:isDefinedBy rdf:resource="http://purl.org/dc/elements/1.1/"/>
<rdfs:label>Creator</rdfs:label>
<rdfs:label xml:lang="en-us">Creator</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.org/dc/elements/1.1/date -->
<owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/date">
<dc:description xml:lang="en-us">Typically, Date will be associated with the creation or
availability of the resource. Recommended best practice
for encoding the date value is defined in a profile of
ISO 8601 [W3CDTF] and follows the YYYY-MM-DD format.</dc:description>
<rdfs:comment xml:lang="en-us">A date associated with an event in the life cycle of the
resource.</rdfs:comment>
<rdfs:isDefinedBy rdf:resource="http://purl.org/dc/elements/1.1/"/>
<rdfs:label>Date</rdfs:label>
<rdfs:label xml:lang="en-us">Date</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.org/dc/elements/1.1/description -->
<owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/description">
<dc:description xml:lang="en-us">Description may include but is not limited to: an abstract,
table of contents, reference to a graphical representation
of content or a free-text account of the content.</dc:description>
<rdfs:comment xml:lang="en-us">An account of the content of the resource.</rdfs:comment>
<rdfs:isDefinedBy rdf:resource="http://purl.org/dc/elements/1.1/"/>
<rdfs:label>Description</rdfs:label>
<rdfs:label xml:lang="en-us">Description</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.org/dc/elements/1.1/format -->
<owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/format">
<dc:description xml:lang="en-us">Typically, Format may include the media-type or dimensions of
the resource. Format may be used to determine the software,
hardware or other equipment needed to display or operate the
resource. Examples of dimensions include size and duration.
Recommended best practice is to select a value from a
controlled vocabulary (for example, the list of Internet Media
Types [MIME] defining computer media formats).</dc:description>
<rdfs:comment xml:lang="en-us">The physical or digital manifestation of the resource.</rdfs:comment>
<rdfs:isDefinedBy rdf:resource="http://purl.org/dc/elements/1.1/"/>
<rdfs:label>Format</rdfs:label>
<rdfs:label xml:lang="en-us">Format</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.org/dc/elements/1.1/identifier -->
<owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/identifier">
<dc:description xml:lang="en-us">Recommended best practice is to identify the resource by means
of a string or number conforming to a formal identification
system.
Example formal identification systems include the Uniform
Resource Identifier (URI) (including the Uniform Resource
Locator (URL)), the Digital Object Identifier (DOI) and the
International Standard Book Number (ISBN).</dc:description>
<rdfs:comment xml:lang="en-us">An unambiguous reference to the resource within a given context.</rdfs:comment>
<rdfs:isDefinedBy rdf:resource="http://purl.org/dc/elements/1.1/"/>
<rdfs:label>Resource Identifier</rdfs:label>
<rdfs:label xml:lang="en-us">Resource Identifier</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.org/dc/elements/1.1/language -->
<owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/language">
<dc:description xml:lang="en-us">Recommended best practice is to use RFC 3066 [RFC3066],
which, in conjunction with ISO 639 [ISO639], defines two-
and three-letter primary language tags with optional
subtags. Examples include "en" or "eng" for English,
"akk" for Akkadian, and "en-GB" for English used in the
United Kingdom.</dc:description>
<rdfs:comment xml:lang="en-us">A language of the intellectual content of the resource.</rdfs:comment>
<rdfs:isDefinedBy rdf:resource="http://purl.org/dc/elements/1.1/"/>
<rdfs:label>Language</rdfs:label>
<rdfs:label xml:lang="en-us">Language</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.org/dc/elements/1.1/member -->
<owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/member"/>
<!-- http://purl.org/dc/elements/1.1/publisher -->
<owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/publisher">
<dc:description xml:lang="en-us">Examples of a Publisher include a person, an organisation,
or a service.
Typically, the name of a Publisher should be used to
indicate the entity.</dc:description>
<rdfs:comment xml:lang="en-us">An entity responsible for making the resource available</rdfs:comment>
<rdfs:isDefinedBy rdf:resource="http://purl.org/dc/elements/1.1/"/>
<rdfs:label>Publisher</rdfs:label>
<rdfs:label xml:lang="en-us">Publisher</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.org/dc/elements/1.1/relation -->
<owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/relation">
<dc:description xml:lang="en-us">
Recommended best practice is to reference the resource by means
of a string or number conforming to a formal identification
system.
</dc:description>
<rdfs:comment xml:lang="en-us">A reference to a related resource.</rdfs:comment>
<rdfs:isDefinedBy rdf:resource="http://purl.org/dc/elements/1.1/"/>
<rdfs:label>Relation</rdfs:label>
<rdfs:label xml:lang="en-us">Relation</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.org/dc/elements/1.1/rights -->
<owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/rights">
<dc:description xml:lang="en-us">
Typically, a Rights element will contain a rights
management statement for the resource, or reference
a service providing such information. Rights information
often encompasses Intellectual Property Rights (IPR),
Copyright, and various Property Rights.
If the Rights element is absent, no assumptions can be made
about the status of these and other rights with respect to
the resource.
</dc:description>
<rdfs:comment xml:lang="en-us">Information about rights held in and over the resource.</rdfs:comment>
<rdfs:isDefinedBy rdf:resource="http://purl.org/dc/elements/1.1/"/>
<rdfs:label>Rights Management</rdfs:label>
<rdfs:label xml:lang="en-us">Rights Management</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.org/dc/elements/1.1/source -->
<owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/source">
<dc:description xml:lang="en-us">The present resource may be derived from the Source resource
in whole or in part. Recommended best practice is to reference
the resource by means of a string or number conforming to a
formal identification system.</dc:description>
<rdfs:comment xml:lang="en-us">A reference to a resource from which the present resource
is derived.</rdfs:comment>
<rdfs:isDefinedBy rdf:resource="http://purl.org/dc/elements/1.1/"/>
<rdfs:label>Source</rdfs:label>
<rdfs:label xml:lang="en-us">Source</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.org/dc/elements/1.1/subject -->
<owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/subject">
<dc:description xml:lang="en-us">Typically, a Subject will be expressed as keywords,
key phrases or classification codes that describe a topic
of the resource. Recommended best practice is to select
a value from a controlled vocabulary or formal
classification scheme.</dc:description>
<rdfs:comment xml:lang="en-us">The topic of the content of the resource.</rdfs:comment>
<rdfs:isDefinedBy rdf:resource="http://purl.org/dc/elements/1.1/"/>
<rdfs:label>Subject and Keywords</rdfs:label>
<rdfs:label xml:lang="en-us">Subject and Keywords</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.org/dc/elements/1.1/title -->
<owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/title">
<dc:description xml:lang="en-us">
Typically, a Title will be a name by which the resource is
formally known.
</dc:description>
<rdfs:comment xml:lang="en-us">A name given to the resource.</rdfs:comment>
<rdfs:isDefinedBy rdf:resource="http://purl.org/dc/elements/1.1/"/>
<rdfs:label>Title</rdfs:label>
<rdfs:label xml:lang="en-us">Title</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.org/dc/elements/1.1/type -->
<owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/type">
<dc:description xml:lang="en-us">Type includes terms describing general categories, functions,
genres, or aggregation levels for content. Recommended best
practice is to select a value from a controlled vocabulary
(for example, the DCMI Type Vocabulary [DCMITYPE]). To
describe the physical or digital manifestation of the
resource, use the Format element.</dc:description>
<rdfs:comment xml:lang="en-us">The nature or genre of the content of the resource.</rdfs:comment>
<rdfs:isDefinedBy rdf:resource="http://purl.org/dc/elements/1.1/"/>
<rdfs:label>Resource Type</rdfs:label>
<rdfs:label xml:lang="en-us">Resource Type</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.org/dc/terms/contributor -->
<owl:AnnotationProperty rdf:about="http://purl.org/dc/terms/contributor"/>
<!-- http://purl.org/dc/terms/created -->
<owl:AnnotationProperty rdf:about="http://purl.org/dc/terms/created"/>
<!-- http://purl.org/dc/terms/license -->
<owl:AnnotationProperty rdf:about="http://purl.org/dc/terms/license">
<obo:IAO_0000117>Mark Miller</obo:IAO_0000117>
<dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2018-05-11T13:47:29Z</dc:date>
</owl:AnnotationProperty>
<!-- http://purl.org/dc/terms/source -->
<owl:AnnotationProperty rdf:about="http://purl.org/dc/terms/source"/>
<!-- http://purl.org/dc/terms/title -->
<owl:AnnotationProperty rdf:about="http://purl.org/dc/terms/title"/>
<!-- http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty -->
<owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty"/>
<!-- http://www.geneontology.org/formats/oboInOwl#created_by -->
<owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#created_by"/>
<!-- http://www.geneontology.org/formats/oboInOwl#creation_date -->
<owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#creation_date"/>
<!-- http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym -->
<owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym">
<obo:IAO_0000115>An alternative label for a class or property which has a more general meaning than the preferred name/primary label.</obo:IAO_0000115>
<obo:IAO_0000117 rdf:resource="http://orcid.org/0000-0001-5208-3432"/>
<obo:IAO_0000233>https://github.com/information-artifact-ontology/ontology-metadata/issues/18</obo:IAO_0000233>
<rdfs:label xml:lang="en">has broad synonym</rdfs:label>
<rdfs:seeAlso>https://github.com/information-artifact-ontology/ontology-metadata/issues/18</rdfs:seeAlso>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000118"/>
</owl:AnnotationProperty>
<!-- http://www.geneontology.org/formats/oboInOwl#hasDbXref -->
<owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasDbXref">
<obo:IAO_0000112>disease characteristic (MONDO:0021125) has cross-reference (http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NCIT:C41009"^^xsd:string</obo:IAO_0000112>
<obo:IAO_0000115>An annotation property that links an ontology entity or a statement to a prefixed identifier or URI.</obo:IAO_0000115>
<obo:IAO_0000233 rdf:resource="https://github.com/information-artifact-ontology/ontology-metadata/issues/123"/>
<terms:contributor rdf:resource="https://orcid.org/0000-0002-7356-1779"/>
<terms:created rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2024-03-18</terms:created>
<rdfs:label>has cross-reference</rdfs:label>
</owl:AnnotationProperty>
<!-- http://www.geneontology.org/formats/oboInOwl#hasExactSynonym -->
<owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym">
<obo:IAO_0000115>An alternative label for a class or property which has the exact same meaning than the preferred name/primary label.</obo:IAO_0000115>
<obo:IAO_0000117 rdf:resource="http://orcid.org/0000-0001-5208-3432"/>
<obo:IAO_0000233>https://github.com/information-artifact-ontology/ontology-metadata/issues/20</obo:IAO_0000233>
<rdfs:label xml:lang="en">has exact synonym</rdfs:label>
<rdfs:seeAlso>https://github.com/information-artifact-ontology/ontology-metadata/issues/20</rdfs:seeAlso>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000118"/>
</owl:AnnotationProperty>
<!-- http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym -->
<owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym">
<obo:IAO_0000115>An alternative label for a class or property which has a more specific meaning than the preferred name/primary label.</obo:IAO_0000115>
<obo:IAO_0000117 rdf:resource="http://orcid.org/0000-0001-5208-3432"/>
<obo:IAO_0000233>https://github.com/information-artifact-ontology/ontology-metadata/issues/19</obo:IAO_0000233>
<rdfs:label xml:lang="en">has narrow synonym</rdfs:label>
<rdfs:seeAlso>https://github.com/information-artifact-ontology/ontology-metadata/issues/19</rdfs:seeAlso>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000118"/>
</owl:AnnotationProperty>
<!-- http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym -->
<owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym">
<obo:IAO_0000115>An alternative label for a class or property that has been used synonymously with the primary term name, but the usage is not strictly correct.</obo:IAO_0000115>
<obo:IAO_0000117 rdf:resource="http://orcid.org/0000-0001-5208-3432"/>
<obo:IAO_0000233>https://github.com/information-artifact-ontology/ontology-metadata/issues/21</obo:IAO_0000233>
<rdfs:label xml:lang="en">has related synonym</rdfs:label>
<rdfs:seeAlso>https://github.com/information-artifact-ontology/ontology-metadata/issues/21</rdfs:seeAlso>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000118"/>
</owl:AnnotationProperty>
<!-- http://www.w3.org/2000/01/rdf-schema#comment -->
<owl:AnnotationProperty rdf:about="http://www.w3.org/2000/01/rdf-schema#comment"/>
<!-- http://www.w3.org/2000/01/rdf-schema#isDefinedBy -->
<owl:AnnotationProperty rdf:about="http://www.w3.org/2000/01/rdf-schema#isDefinedBy"/>
<!-- http://www.w3.org/2000/01/rdf-schema#label -->
<owl:AnnotationProperty rdf:about="http://www.w3.org/2000/01/rdf-schema#label">
<obo:IAO_0000111>label</obo:IAO_0000111>
<rdfs:label>label</rdfs:label>
</owl:AnnotationProperty>
<!-- http://www.w3.org/2000/01/rdf-schema#seeAlso -->
<owl:AnnotationProperty rdf:about="http://www.w3.org/2000/01/rdf-schema#seeAlso"/>
<!-- http://xmlns.com/foaf/0.1/homepage -->
<owl:AnnotationProperty rdf:about="http://xmlns.com/foaf/0.1/homepage"/>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Datatypes
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!-- http://www.w3.org/1999/02/22-rdf-syntax-ns#PlainLiteral -->
<rdfs:Datatype rdf:about="http://www.w3.org/1999/02/22-rdf-syntax-ns#PlainLiteral"/>
<!-- http://www.w3.org/2000/01/rdf-schema#Literal -->
<rdfs:Datatype rdf:about="http://www.w3.org/2000/01/rdf-schema#Literal"/>
<!-- http://www.w3.org/2001/XMLSchema#date -->
<rdfs:Datatype rdf:about="http://www.w3.org/2001/XMLSchema#date"/>
<!-- http://www.w3.org/2001/XMLSchema#float -->
<rdfs:Datatype rdf:about="http://www.w3.org/2001/XMLSchema#float"/>
<!-- http://www.w3.org/2001/XMLSchema#integer -->
<rdfs:Datatype rdf:about="http://www.w3.org/2001/XMLSchema#integer"/>
<!-- http://www.w3.org/2001/XMLSchema#nonNegativeInteger -->
<rdfs:Datatype rdf:about="http://www.w3.org/2001/XMLSchema#nonNegativeInteger"/>
<!-- http://www.w3.org/2001/XMLSchema#string -->
<rdfs:Datatype rdf:about="http://www.w3.org/2001/XMLSchema#string"/>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Object Properties
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!-- http://purl.obolibrary.org/obo/BFO_0000050 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000050">
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<obo:IAO_0000111 xml:lang="en">is part of</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">my brain is part of my body (continuant parthood, two material entities)</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">my stomach cavity is part of my stomach (continuant parthood, immaterial entity is part of material entity)</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">this day is part of this year (occurrent parthood)</obo:IAO_0000112>
<obo:IAO_0000115 xml:lang="en">a core relation that holds between a part and its whole</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">Everything is part of itself. Any part of any part of a thing is itself part of that thing. Two distinct things cannot be part of each other.</obo:IAO_0000116>
<obo:IAO_0000116 xml:lang="en">Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/</obo:IAO_0000116>
<obo:IAO_0000116 xml:lang="en">Parthood requires the part and the whole to have compatible classes: only an occurrent can be part of an occurrent; only a process can be part of a process; only a continuant can be part of a continuant; only an independent continuant can be part of an independent continuant; only an immaterial entity can be part of an immaterial entity; only a specifically dependent continuant can be part of a specifically dependent continuant; only a generically dependent continuant can be part of a generically dependent continuant. (This list is not exhaustive.)
A continuant cannot be part of an occurrent: use 'participates in'. An occurrent cannot be part of a continuant: use 'has participant'. A material entity cannot be part of an immaterial entity: use 'has location'. A specifically dependent continuant cannot be part of an independent continuant: use 'inheres in'. An independent continuant cannot be part of a specifically dependent continuant: use 'bearer of'.</obo:IAO_0000116>
<obo:IAO_0000118 xml:lang="en">part_of</obo:IAO_0000118>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<rdfs:label xml:lang="en">part of</rdfs:label>
<rdfs:seeAlso>http://www.obofoundry.org/ro/#OBO_REL:part_of</rdfs:seeAlso>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/BFO_0000051 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000051">
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<obo:IAO_0000111 xml:lang="en">has part</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">my body has part my brain (continuant parthood, two material entities)</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">my stomach has part my stomach cavity (continuant parthood, material entity has part immaterial entity)</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">this year has part this day (occurrent parthood)</obo:IAO_0000112>
<obo:IAO_0000115 xml:lang="en">a core relation that holds between a whole and its part</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">Everything has itself as a part. Any part of any part of a thing is itself part of that thing. Two distinct things cannot have each other as a part.</obo:IAO_0000116>
<obo:IAO_0000116 xml:lang="en">Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/</obo:IAO_0000116>
<obo:IAO_0000116 xml:lang="en">Parthood requires the part and the whole to have compatible classes: only an occurrent have an occurrent as part; only a process can have a process as part; only a continuant can have a continuant as part; only an independent continuant can have an independent continuant as part; only a specifically dependent continuant can have a specifically dependent continuant as part; only a generically dependent continuant can have a generically dependent continuant as part. (This list is not exhaustive.)
A continuant cannot have an occurrent as part: use 'participates in'. An occurrent cannot have a continuant as part: use 'has participant'. An immaterial entity cannot have a material entity as part: use 'location of'. An independent continuant cannot have a specifically dependent continuant as part: use 'bearer of'. A specifically dependent continuant cannot have an independent continuant as part: use 'inheres in'.</obo:IAO_0000116>
<obo:IAO_0000118 xml:lang="en">has_part</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<rdfs:label xml:lang="en">has part</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/BFO_0000054 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000054">
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000017"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
<obo:IAO_0000111 xml:lang="en">realized in</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">this disease is realized in this disease course</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">this fragility is realized in this shattering</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">this investigator role is realized in this investigation</obo:IAO_0000112>
<obo:IAO_0000118 xml:lang="en">is realized by</obo:IAO_0000118>
<obo:IAO_0000118 xml:lang="en">realized_in</obo:IAO_0000118>
<obo:IAO_0000600 xml:lang="en">[copied from inverse property 'realizes'] to say that b realizes c at t is to assert that there is some material entity d & b is a process which has participant d at t & c is a disposition or role of which d is bearer_of at t& the type instantiated by b is correlated with the type instantiated by c. (axiom label in BFO2 Reference: [059-003])</obo:IAO_0000600>
<rdfs:comment>Paraphrase of elucidation: a relation between a realizable entity and a process, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process</rdfs:comment>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
<rdfs:label xml:lang="en">realized in</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/BFO_0000055 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000055">
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000017"/>
<obo:IAO_0000111 xml:lang="en">realizes</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">this disease course realizes this disease</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">this investigation realizes this investigator role</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">this shattering realizes this fragility</obo:IAO_0000112>
<obo:IAO_0000600 xml:lang="en">to say that b realizes c at t is to assert that there is some material entity d & b is a process which has participant d at t & c is a disposition or role of which d is bearer_of at t& the type instantiated by b is correlated with the type instantiated by c. (axiom label in BFO2 Reference: [059-003])</obo:IAO_0000600>
<rdfs:comment>Paraphrase of elucidation: a relation between a process and a realizable entity, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process</rdfs:comment>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">realizes</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/BFO_0000062 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000062">
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000063"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
<obo:IAO_0000111 xml:lang="en">preceded by</obo:IAO_0000111>
<obo:IAO_0000116 xml:lang="en">An example is: translation preceded_by transcription; aging preceded_by development (not however death preceded_by aging). Where derives_from links classes of continuants, preceded_by links classes of processes. Clearly, however, these two relations are not independent of each other. Thus if cells of type C1 derive_from cells of type C, then any cell division involving an instance of C1 in a given lineage is preceded_by cellular processes involving an instance of C. The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P. Note that an assertion to the effect that P preceded_by P1 is rather weak; it tells us little about the relations between the underlying instances in virtue of which the preceded_by relation obtains. Typically we will be interested in stronger relations, for example in the relation immediately_preceded_by, or in relations which combine preceded_by with a condition to the effect that the corresponding instances of P and P1 share participants, or that their participants are connected by relations of derivation, or (as a first step along the road to a treatment of causality) that the one process in some way affects (for example, initiates or regulates) the other.</obo:IAO_0000116>
<obo:IAO_0000118 xml:lang="en">is preceded by</obo:IAO_0000118>
<obo:IAO_0000118 xml:lang="en">preceded_by</obo:IAO_0000118>
<dc:source>http://www.obofoundry.org/ro/#OBO_REL:preceded_by</dc:source>
<rdfs:label xml:lang="en">preceded by</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/BFO_0000063 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000063">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002222"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
<obo:IAO_0000111 xml:lang="en">precedes</obo:IAO_0000111>
<rdfs:label xml:lang="en">precedes</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/BFO_0000066 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000066">
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000067"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000066"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000066"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
</owl:propertyChainAxiom>
<obo:IAO_0000111 xml:lang="en">occurs in</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t</obo:IAO_0000115>
<obo:IAO_0000118 xml:lang="en">occurs_in</obo:IAO_0000118>
<obo:IAO_0000118 xml:lang="en">unfolds in</obo:IAO_0000118>
<obo:IAO_0000118 xml:lang="en">unfolds_in</obo:IAO_0000118>
<rdfs:comment>Paraphrase of definition: a relation between a process and an independent continuant, in which the process takes place entirely within the independent continuant</rdfs:comment>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
<rdfs:label xml:lang="en">occurs in</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/BFO_0000067 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000067">
<obo:IAO_0000111 xml:lang="en">site of</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">[copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t</obo:IAO_0000115>
<rdfs:comment>Paraphrase of definition: a relation between an independent continuant and a process, in which the process takes place entirely within the independent continuant</rdfs:comment>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
<rdfs:label xml:lang="en">contains process</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0000039 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000039">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#FunctionalProperty"/>
<obo:IAO_0000111 xml:lang="en">has measurement unit label</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">has measurement unit label</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0000136 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000136">
<obo:IAO_0000111 xml:lang="en">is about</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A (currently) primitive relation that relates an information artifact to an entity.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">is about</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0000219 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000219">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<obo:IAO_0000111 xml:lang="en">denotes</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A primitive, instance-level, relation obtaining between an information content entity and some portion of reality. Denotation is what happens when someone creates an information content entity E in order to specifically refer to something. The only relation between E and the thing is that E can be used to 'pick out' the thing. This relation connects those two together. Freedictionary.com sense 3: To signify directly; refer to specifically</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">denotes</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0000221 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000221">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<obo:IAO_0000111 xml:lang="en">is quality measurement of</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">m is a quality measurement of q at t. When q is a quality, there is a measurement process p that has specified output m, a measurement datum, that is about q</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">is quality measurement of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0000235 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000235">
<obo:IAO_0000111 xml:lang="en">denoted by</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">inverse of the relation 'denotes'</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">denoted by</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0000407 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000407">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#FunctionalProperty"/>
<obo:IAO_0000111 xml:lang="en">has coordinate unit label</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">has coordinate unit label</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/IAO_0000413 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000413">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<obo:IAO_0000111 xml:lang="en">is duration of</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">relates a process to a time-measurement-datum that represents the duration of the process</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">is duration of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0000107 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000107">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/OBI_0001173"/>
<obo:IAO_0000111>provides_service_consumer_with</obo:IAO_0000111>
<obo:IAO_0000112>The provides_service_consumer_with relation links the service to its primary process it provides for the consumer (as opposed to secondary processual parts of a service process such as payment or documentation). For example, a 'DNA sequencing service' provides_service_consumer_with 'DNA sequencing' as the essential process performed by the provider for the client.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A relation between a service and the primary processual part of the service that is performed by the provider for the consumer.</obo:IAO_0000115>
<rdfs:label>provides_service_consumer_with</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0000124 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000124">
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/OBI_0001909"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
<obo:IAO_0000111>is_supported_by_data</obo:IAO_0000111>
<obo:IAO_0000112>The relation between the conclusion "Gene tpbA is involved in EPS production" and the data items produced using two sets of organisms, one being a tpbA knockout, the other being tpbA wildtype tested in polysacharide production assays and analyzed using an ANOVA.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">The relation between a data item and a conclusion where the conclusion is the output of a data interpreting process and the data item is used as an input to that process</obo:IAO_0000115>
<obo:IAO_0000117>OBI</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000119>Philly 2011 workshop</obo:IAO_0000119>
<rdfs:label>is_supported_by_data</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0000293 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000293">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000295"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<obo:IAO_0000111>has specified input</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">see is_input_of example_of_usage</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">The inverse property of is specified input of</obo:IAO_0000115>
<obo:IAO_0000116>8/17/09: specified inputs of one process are not necessarily specified inputs of a larger process that it is part of. This is in contrast to how 'has participant' works.</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">PERSON: Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Larry Hunter</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Melanie Coutot</obo:IAO_0000117>
<rdfs:label xml:lang="en">has specified input</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0000294 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000294">
<rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteProperty"/>
<obo:IAO_0000111>is_concretization_of</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Is a relationship between a generically dependent continuant and a specifically dependent continuant. A generically dependent continuant may inhere in more than one entity. It does so by virtue of the fact that there is, for each entity that it inheres, a specifically dependent *concretization* of the generically dependent continuant that is specifically dependent. For instance, consider a story, which is an information artifact that inheres in some number of books. Each book bears some quality that carries the story. The relation between this quality and the generically dependent continuant is that the former is the concretization of the latter.</obo:IAO_0000115>
<obo:IAO_0000116>replaced by: http://purl.obolibrary.org/obo/BFO_0000058</obo:IAO_0000116>
<obo:IAO_0000117>PERSON: Alan Ruttenburg</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Barry Smith</obo:IAO_0000117>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<rdfs:label xml:lang="en">obsolete_is_concretization_of</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0000295 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000295">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<obo:IAO_0000111>is specified input of</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">some Autologous EBV(Epstein-Barr virus)-transformed B-LCL (B lymphocyte cell line) is_input_for instance of Chromum Release Assay described at https://wiki.cbil.upenn.edu/obiwiki/index.php/Chromium_Release_assay</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A relation between a planned process and a continuant participating in that process that is not created during the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000117>PERSON:Bjoern Peters</obo:IAO_0000117>
<rdfs:label xml:lang="en">is specified input of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0000297 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000297">
<rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteProperty"/>
<obo:IAO_0000111>is_concretized_as</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Is a relationship between a specifically dependent continuant and a generically dependent continuant. A generically dependent continuant may inhere in more than one entity. It does so by virtue of the fact that there is, for each entity that it inheres, a specifically dependent *concretization* of the generically dependent continuant that is specifically dependent. For instance, consider a story, which is an information artifact that inheres in some number of books. Each book bears some quality that carries the story. The relation between this quality and the generically dependent continuant is that the former is the concretization of the latter.</obo:IAO_0000115>
<obo:IAO_0000116>replaced by: http://purl.obolibrary.org/obo/BFO_0000059</obo:IAO_0000116>
<obo:IAO_0000117>PERSON: Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Barry Smith</obo:IAO_0000117>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<rdfs:label xml:lang="en">obsolete_is_concretized_as</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0000298 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000298">
<rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteProperty"/>
<obo:IAO_0000111>has_quality</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A relation between an entity and a quality. For types: E has_quality Q iff:
for any eEt, exists qQt such that q inheres_in e at t.
For instances: e has_quality q at t iff q inheres_in e at t and q instance-of Quality [GOC:cjm]</obo:IAO_0000115>
<obo:IAO_0000116>replaced by: http://purl.obolibrary.org/obo/BFO_0000086</obo:IAO_0000116>
<obo:IAO_0000117>GROUP:OBI:<http://obi.sourceforge.net></obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<rdfs:label xml:lang="en">obsolete_has_quality</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0000299 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000299">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<obo:IAO_0000111>has specified output</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">The inverse property of is specified output of</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON: Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Larry Hunter</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Melanie Courtot</obo:IAO_0000117>
<rdfs:label xml:lang="en">has specified output</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0000300 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000300">
<rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteProperty"/>
<obo:IAO_0000111>is_realized_by</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">Relation between a realizable and a process. Reciprocal relation of realizes [GOC:cjm]</obo:IAO_0000115>
<obo:IAO_0000116>replaced by http://purl.obolibrary.org/obo/BFO_0000054: 'is realized by'</obo:IAO_0000116>
<obo:IAO_0000117>GROUP:OBI:<http://obi.sourceforge.net></obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>executed_during</obo:IAO_0000118>
<obo:IAO_0000118>has_realization</obo:IAO_0000118>
<obo:IAO_0000118>is_realized_as</obo:IAO_0000118>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<rdfs:label xml:lang="en">obsolete_is_realized_by</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0000301 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000301">
<rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteProperty"/>
<obo:IAO_0000111>obsoleted_has_specified_output_information</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A relation between a participant in a process, that produces a data set . The process is the realization of a concretization of a realizable information entity (objective specification or plan specification). In general, not all data present at the end of the process are specified_data.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON: Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label xml:lang="en">obsoleted_has_specified_output_information</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0000304 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000304">
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111 xml:lang="en">is_manufactured_by</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">http://www.affymetrix.com/products/arrays/specific/hgu133.affx is_manufactered_by http://www.affymetrix.com/ (if we decide to use these URIs for the actual entities)</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">c is_manufactured_by o means that there was a process p in which c was built in which a person, or set of people or machines did the work(bore the "Manufacturer Role", and those people/and or machines were members or of directed by the organization to do this.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Liju Fan</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">has_make</obo:IAO_0000118>
<obo:IAO_0000118 xml:lang="en">has_manufacturer</obo:IAO_0000118>
<rdfs:label xml:lang="en">is_manufactured_by</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0000306 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000306">
<rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteProperty"/>
<obo:IAO_0000111>has_function</obo:IAO_0000111>
<obo:IAO_0000112>heart has_function to-pump-blood</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">Relation between an independent continuant and a function.</obo:IAO_0000115>
<obo:IAO_0000116>replaced by: http://purl.obolibrary.org/obo/BFO_0000085</obo:IAO_0000116>
<obo:IAO_0000117>GROUP:OBI:<http://obi.sourceforge.net></obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<rdfs:label xml:lang="en">obsolete_has_function</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0000307 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000307">
<rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteProperty"/>
<obo:IAO_0000111>obsoleted_is_reagent_in</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">some Triton X-100 (Sigma-Aldrich) is_reagent_in instance of Chromium Release Assay described at https://wiki.cbil.upenn.edu/obiwiki/index.php/Chromium_Release_assay</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Relationship between a substance and a protocol application in which it participates, where the substance has a ReagentRole</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label xml:lang="en">obsoleted_is_reagent_in</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0000308 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000308">
<rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteProperty"/>
<obo:IAO_0000111>realizes</obo:IAO_0000111>
<obo:IAO_0000112>example of usage: The process of 'histidine catabolism' (GO:0006548) realizes the
function 'histidine ammonia lyase activity' (GO:0004397) (note: here 'activity'
denotes a function and not a process). We leave open the possibility of defining
in future the sub-relations directly_realizes (as bewteen a function and it's
functioning) and indirectly_realizes.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">Relation between a process and a function, where the unfolding of the
process requires the execution of the function. Class level: P realizes F iff:
given any p that instantiates P, there exists some f, t such that f instantiates
F at t and p *realizes* f. Here, *realizes* is the primitive
instance level relation [GOC:cjm]</obo:IAO_0000115>
<obo:IAO_0000116>replaced by http://purl.obolibrary.org/obo/BFO_0000055: 'realizes'</obo:IAO_0000116>
<obo:IAO_0000117>GROUP:OBI:<http://obi.sourceforge.net></obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Chris Mungal</obo:IAO_0000117>
<obo:IAO_0000118>executes</obo:IAO_0000118>
<obo:IAO_0000118>has_function_part</obo:IAO_0000118>
<obo:IAO_0000118>involves_execution_of</obo:IAO_0000118>
<obo:IAO_0000118>is_realization_of</obo:IAO_0000118>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<rdfs:label xml:lang="en">obsolete_realizes</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0000309 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000309">
<rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteProperty"/>
<obo:IAO_0000111>obsoleted_utilizes_reagent</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">see example_of_usage for is_reagent_in</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Relationship between a protocol application and a substance that has role reagent that participates in the protocol application</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label xml:lang="en">obsoleted_utilizes_reagent</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0000311 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000311">
<rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteProperty"/>
<obo:IAO_0000111>obsoleted_is_device_for</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">some LKB 1272 Clinigamma counter is_device_for instance of Chromium Release Assay described at https://wiki.cbil.upenn.edu/obiwiki/index.php/Chromium_Release_assay</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Relationship between a device and a protocol application in which it participates</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label xml:lang="en">obsoleted_is_device_for</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0000312 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000312">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<obo:IAO_0000111>is specified output of</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000117>PERSON:Bjoern Peters</obo:IAO_0000117>
<rdfs:label xml:lang="en">is specified output of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0000313 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000313">
<rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteProperty"/>
<obo:IAO_0000111>obsoleted_utilizes_device</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">see example_of_usage for is_device_for</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Relationship between protocol application and an intrument in which it participates</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label xml:lang="en">obsoleted_utilizes_device</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0000314 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000314">
<obo:IAO_0000111>is_proxy_for</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">position on a gel is_proxy_for mass and charge of molecule in an western blot. Florescent intensity is_proxy_for amount of protein labeled with GFP. Examples:
A260/A280 (of a DNA sample) is_proxy_for DNA-purity. NMR Sample scan is a proxy for sample quality.
Within the assay mentioned here: https://wiki.cbil.upenn.edu/obiwiki/index.php/Chromium_Release_assay
level of radioactivity is_proxy_for level of toxicity</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A relation between continuant instances c1 and c2 where within an experiment/ protocol application, measurement of c1 is used to determine what a measurement of c2 would be.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">A relation between continuant instances c1 and c2 where within a protocol
application, measurement of c1 is related to a what would be the
measurement of c2.
(another definition)</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Alan Ruttenberg</obo:IAO_0000117>
<rdfs:label xml:lang="en">is_proxy_for</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0000315 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000315">
<rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteProperty"/>
<obo:IAO_0000111>has specified input information</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A relation between a process and a participant in that process, that consumes a data set . The process is the realization of a concretization of a directive information entity (objective specification or plan specification). In general, not all data present at the beginning of the process are specified_data.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">PERSON:Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000118>consumes data</obo:IAO_0000118>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label xml:lang="en">obsoleted_has_specified_input_information</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0000316 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000316">
<rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteProperty"/>
<obo:IAO_0000111>has_role</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A relation between a continuant C and a role R. The reciprocal relation of role_of.</obo:IAO_0000115>
<obo:IAO_0000116>replaced by: http://purl.obolibrary.org/obo/BFO_0000087</obo:IAO_0000116>
<obo:IAO_0000117>GROUP:OBI:<http://obi.sourceforge.net></obo:IAO_0000117>
<obo:IAO_0000117>PERSON:Chris Mungal</obo:IAO_0000117>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<rdfs:label xml:lang="en">obsolete_has_role</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0000365 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000365">
<rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteProperty"/>
<obo:IAO_0000111>obsolete_results_from</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000116>2009/11/23: BP, dev call:o bsoleted as discussed in tracker https://sourceforge.net/tracker/?func=detail&aid=2899860&group_id=177891&atid=886178
. Should be replaced by instead creating defined classes for materials, which are specified output of the process that conveys the</obo:IAO_0000116>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_results_from</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0000417 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000417">
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000833"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/IAO_0000005"/>
<obo:IAO_0000111>achieves_planned_objective</obo:IAO_0000111>
<obo:IAO_0000112>A cell sorting process achieves the objective specification 'material separation objective'</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">This relation obtains between a planned process and a objective specification when the criteria specified in the objective specification are met at the end of the planned process.</obo:IAO_0000115>
<obo:IAO_0000117>BP, AR, PPPB branch</obo:IAO_0000117>
<obo:IAO_0000119>PPPB branch derived</obo:IAO_0000119>
<obo:IAO_0000232>modified according to email thread from 1/23/09 in accordince with DT and PPPB branch</obo:IAO_0000232>
<rdfs:label>achieves_planned_objective</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0000459 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000459">
<rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteProperty"/>
<obo:IAO_0000111>is_specified_information_output_of</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A relation between a data set and the process in which it participates and was produced. Inverse of outputs_specified_data relation.</obo:IAO_0000115>
<obo:IAO_0000116>is replaced by has_specified_output_of</obo:IAO_0000116>
<obo:IAO_0000117>PERSON: James Malone</obo:IAO_0000117>
<obo:IAO_0000119>Editor</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsoleted_is_specified_information_output_of</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0000643 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000643">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<obo:IAO_0000111>has grain</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">the relation of the cells in the finger of the skin to the finger, in which an indeterminate number of grains are parts of the whole by virtue of being grains in a collective that is part of the whole, and in which removing one granular part does not nec- essarily damage or diminish the whole. Ontological Whether there is a fixed, or nearly fixed number of parts - e.g. fingers of the hand, chambers of the heart, or wheels of a car - such that there can be a notion of a single one being missing, or whether, by contrast, the number of parts is indeterminate - e.g., cells in the skin of the hand, red cells in blood, or rubber molecules in the tread of the tire of the wheel of the car.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">Discussion in Karslruhe with, among others, Alan Rector, Stefan Schulz, Marijke Keet, Melanie Courtot, and Alan Ruttenberg. Definition take from the definition of granular parthood in the cited paper. Needs work to put into standard form</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">PERSON: Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000119>PAPER: Granularity, scale and collectivity: When size does and does not matter, Alan Rector, Jeremy Rogers, Thomas Bittner, Journal of Biomedical Informatics 39 (2006) 333-349</obo:IAO_0000119>
<rdfs:label>has grain</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0000644 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000644">
<rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteProperty"/>
<obo:IAO_0000111>obsoleted_is_specified_information_intput_of</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Is the inverse relation of has_specfied_input_information</obo:IAO_0000115>
<obo:IAO_0000116>is replaced by is_specified_intput_of</obo:IAO_0000116>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsoleted_is_specified_information_intput_of</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0000645 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000645">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<obo:IAO_0000111>is grain of</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A relation between granular parts and the whole of which they are a part. Granular parts have indeterminate number such that removing one granular part does not necessarily damage or diminish the whole.</obo:IAO_0000115>
<obo:IAO_0000116>JAO: Added definition 2013-10-25 based on 'has grain', but both these terms seem problematic.</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">PERSON: Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">Discussion in Karslruhe with, among others, Alan Rector, Stefan Schulz, Marijke Keet, Melanie Courtot, and Alan Ruttenberg. With inspiration from the paper Granularity, scale and collectivity: When size does and does not matter, Alan Recto, Jeremy Rogers, Thomas Bittner, Journal of Biomedical Informatics 39 (2006) 333-349</obo:IAO_0000119>
<rdfs:label xml:lang="en">is grain of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0000646 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000646">
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000647"/>
<obo:IAO_0000111>provisions</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A relation between an organisation or person and a material entity, where the organization or person provides or supplies the material entity for others to use</obo:IAO_0000115>
<obo:IAO_0000116>5/11/2020: A prior definition contained reference to transfer of ownership. ("A relation between an organisation or person and a material entity who owned or has license to the material entity and there was a legal transfer of ownership or licensing of the material entity to the current owner"). This was left out as it was hard to read and it was unclear if/how that transfer restricts the relationship.</obo:IAO_0000116>
<obo:IAO_0000117>GROUP: Relations branch</obo:IAO_0000117>
<obo:IAO_0000118>supplies</obo:IAO_0000118>
<rdfs:label>provisions</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0000647 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000647">
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<rdfs:range>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000245"/>
</owl:unionOf>
</owl:Class>
</rdfs:range>
<obo:IAO_0000111>has_supplier</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A relation between a material entity and an organisation or person who owned or has license to the material entity and there was a legal transfer of ownership or licensing of the material entity to the current owner.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Alan Rutternberg</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Cristian Cocos</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Melanie Courtot</obo:IAO_0000117>
<rdfs:label>has_supplier</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0000833 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000833">
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/IAO_0000005"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<obo:IAO_0000111>objective_achieved_by</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">This relation obtains between an objective specification and a planned process when the criteria specified in the objective specification are met at the end of the planned process.</obo:IAO_0000115>
<obo:IAO_0000117>OBI</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>objective_achieved_by</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0000846 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000846">
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001688"/>
<rdfs:domain>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000245"/>
</owl:unionOf>
</owl:Class>
</rdfs:domain>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/OBI_0000245"/>
<obo:IAO_0000111>is member of organization</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Relating a legal person or organization to an organization in the case where the legal person or organization has a role as member of the organization.</obo:IAO_0000115>
<obo:IAO_0000116>2009/10/01 Alan Ruttenberg. Barry prefers generic is-member-of. Question of what the range should be. For now organization. Is organization a population? Would the same relation be used to record members of a population</obo:IAO_0000116>
<obo:IAO_0000116>JZ: Discussed on May 7, 2012 OBI dev call. Bjoern points out that we need to allow for organizations to be members of organizations. And agreed by the other OBI developers. So, human and organization were specified in 'Domains'. The textual definition was updated based on it.</obo:IAO_0000116>
<obo:IAO_0000117>Person:Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000117>Person:Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000119>Person:Alan Ruttenberg</obo:IAO_0000119>
<obo:IAO_0000119>Person:Helen Parkinson</obo:IAO_0000119>
<obo:IAO_0000232>2009/09/28 Alan Ruttenberg. Fucoidan-use-case</obo:IAO_0000232>
<rdfs:label>is member of organization</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0000999 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000999">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/OBI_0000938"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/OBI_0000963"/>
<obo:IAO_0000111>has category label</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A relation between a categorical measurement data item and the categorical label that indicates the value of that data item on the categorical scale.</obo:IAO_0000115>
<rdfs:label>has category label</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0001637 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0001637">
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#SymmetricProperty"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000111>has disposition to bind</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A relationship between two material entitites that each have disposition to form a complex with the other.</obo:IAO_0000115>
<obo:IAO_0000116>This is a shortcut relation, and should expand to say that the two material entities have dispositions, point to the process in which they from a complex that realizes those dispositions, and points to the complex in which the two entities are 'bound to' each other</obo:IAO_0000116>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>has disposition to bind</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0001688 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0001688">
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/OBI_0000245"/>
<rdfs:range>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000245"/>
</owl:unionOf>
</owl:Class>
</rdfs:range>
<obo:IAO_0000111 xml:lang="en">has organization member</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Relating an organization to a legal person or organization.</obo:IAO_0000115>
<obo:IAO_0000116>See tracker:
https://sourceforge.net/tracker/index.php?func=detail&aid=3512902&group_id=177891&atid=886178</obo:IAO_0000116>
<obo:IAO_0000117>Person: Jie Zheng</obo:IAO_0000117>
<rdfs:label xml:lang="en">has organization member</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0001927 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0001927">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/OBI_0001933"/>
<obo:IAO_0000111>specifies value of</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A relation between a value specification and an entity which the specification is about.</obo:IAO_0000115>
<rdfs:label>specifies value of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0001938 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0001938">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/OBI_0001933"/>
<obo:IAO_0000111>has value specification</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A relation between an information content entity and a value specification that specifies its value.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: James A. Overton</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>has value specification</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0001950 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0001950">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<rdfs:range>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000245"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000968"/>
</owl:unionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000202"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:range>
<obo:IAO_0000111 xml:lang="en">has performer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000115 xml:lang="en">A relation between a planned process and a continuant where the continuant can be a person, organization or device (such as a robot controlled by software workflow management system) that performs the planned process.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">OBI</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:comment>The 'has performer' relation covers the need to report on who performed a planned processed. It has to cover processes done by People or Devices (such as a robot controlled by software WF management system).</rdfs:comment>
<rdfs:label xml:lang="en">has performer</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0003385 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0003385">
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000111>has assay target context</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A relation between the target entity of an assay and a material entity, where the material entity is the environment in which the target entity of an assay is measured, such as a live mouse, cell culture, test tube, etc.</obo:IAO_0000115>
<obo:IAO_0000117>Hector Guzman-Orozco</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1516</obo:IAO_0000233>
<rdfs:label>has assay target context</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_1110060 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_1110060">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002087"/>
<obo:IAO_0000111>process is result of</obo:IAO_0000111>
<obo:IAO_0000112>The production of IFN-gamma by effector T cells is a process result of T cell stimulation through the TCR</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">is a relationship between a process and a preceding occurrent that directly caused the later one to occur</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000117>PERSON:Bjoern Peters</obo:IAO_0000117>
<rdfs:label>process is result of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_1110112 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_1110112">
<rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteProperty"/>
<obo:IAO_0000111>is_described_by</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_is_described_by</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/OBI_1110119 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_1110119">
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000111>bound_to</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A relationship between two material entities that form a complex based on a selective, non-covalent interaction.</obo:IAO_0000115>
<obo:IAO_0000116>The definition of this term is modeled after the Chebi:50967 and GO:0005488 terms. Further alignment of the logical definitions with those ontologies will require agreement on the placement of GO:molecular function in BFO among other things. OBI will retire this term once such an alignment is achieved as 'bound to' is not in the primary OBI scope.</obo:IAO_0000116>
<rdfs:label>bound_to</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0000052 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000052">
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000053"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#FunctionalProperty"/>
<obo:IAO_0000111 xml:lang="en">inheres in</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">this fragility is a characteristic of this vase</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">this red color is a characteristic of this apple</obo:IAO_0000112>
<obo:IAO_0000115 xml:lang="en">a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence.</obo:IAO_0000115>
<obo:IAO_0000118 xml:lang="en">inheres_in</obo:IAO_0000118>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<rdfs:comment>Note that this relation was previously called "inheres in", but was changed to be called "characteristic of" because BFO2 uses "inheres in" in a more restricted fashion. This relation differs from BFO2:inheres_in in two respects: (1) it does not impose a range constraint, and thus it allows qualities of processes, as well as of information entities, whereas BFO2 restricts inheres_in to only apply to independent continuants (2) it is declared functional, i.e. something can only be a characteristic of one thing.</rdfs:comment>
<rdfs:label xml:lang="en">characteristic of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0000053 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000053">
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#InverseFunctionalProperty"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000020"/>
<obo:IAO_0000111 xml:lang="en">bearer of</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">this apple is bearer of this red color</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">this vase is bearer of this fragility</obo:IAO_0000112>
<obo:IAO_0000115 xml:lang="en">Inverse of characteristic_of</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">A bearer can have many dependents, and its dependents can exist for different periods of time, but none of its dependents can exist when the bearer does not exist.</obo:IAO_0000116>
<obo:IAO_0000118 xml:lang="en">bearer_of</obo:IAO_0000118>
<obo:IAO_0000118 xml:lang="en">is bearer of</obo:IAO_0000118>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<rdfs:label xml:lang="en">has characteristic</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0000056 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000056">
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
<obo:IAO_0000111 xml:lang="en">participates in</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">this blood clot participates in this blood coagulation</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">this input material (or this output material) participates in this process</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">this investigator participates in this investigation</obo:IAO_0000112>
<obo:IAO_0000115 xml:lang="en">a relation between a continuant and a process, in which the continuant is somehow involved in the process</obo:IAO_0000115>
<obo:IAO_0000118 xml:lang="en">participates_in</obo:IAO_0000118>
<rdfs:label xml:lang="en">participates in</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0000057 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000057">
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
<obo:IAO_0000111 xml:lang="en">has participant</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">this blood coagulation has participant this blood clot</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">this investigation has participant this investigator</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">this process has participant this input material (or this output material)</obo:IAO_0000112>
<obo:IAO_0000115 xml:lang="en">a relation between a process and a continuant, in which the continuant is somehow involved in the process</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time.</obo:IAO_0000116>
<obo:IAO_0000118 xml:lang="en">has_participant</obo:IAO_0000118>
<terms:source>http://www.obofoundry.org/ro/#OBO_REL:has_participant</terms:source>
<rdfs:label xml:lang="en">has participant</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0000058 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000058">
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000059"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000031"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000020"/>
<obo:IAO_0000112 xml:lang="en">A journal article is an information artifact that inheres in some number of printed journals. For each copy of the printed journal there is some quality that carries the journal article, such as a pattern of ink. The journal article (a generically dependent continuant) is concretized as the quality (a specifically dependent continuant), and both depend on that copy of the printed journal (an independent continuant).</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">An investigator reads a protocol and forms a plan to carry out an assay. The plan is a realizable entity (a specifically dependent continuant) that concretizes the protocol (a generically dependent continuant), and both depend on the investigator (an independent continuant). The plan is then realized by the assay (a process).</obo:IAO_0000112>
<obo:IAO_0000115 xml:lang="en">A relationship between a generically dependent continuant and a specifically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. A generically dependent continuant may be concretized as multiple specifically dependent continuants.</obo:IAO_0000115>
<rdfs:label xml:lang="en">is concretized as</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0000059 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000059">
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000020"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000031"/>
<obo:IAO_0000112 xml:lang="en">A journal article is an information artifact that inheres in some number of printed journals. For each copy of the printed journal there is some quality that carries the journal article, such as a pattern of ink. The quality (a specifically dependent continuant) concretizes the journal article (a generically dependent continuant), and both depend on that copy of the printed journal (an independent continuant).</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">An investigator reads a protocol and forms a plan to carry out an assay. The plan is a realizable entity (a specifically dependent continuant) that concretizes the protocol (a generically dependent continuant), and both depend on the investigator (an independent continuant). The plan is then realized by the assay (a process).</obo:IAO_0000112>
<obo:IAO_0000115 xml:lang="en">A relationship between a specifically dependent continuant and a generically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. Multiple specifically dependent continuants can concretize the same generically dependent continuant.</obo:IAO_0000115>
<rdfs:label xml:lang="en">concretizes</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0000079 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000079">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
<obo:IAO_0000112 xml:lang="en">this catalysis function is a function of this enzyme</obo:IAO_0000112>
<obo:IAO_0000115 xml:lang="en">a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">A function inheres in its bearer at all times for which the function exists, however the function need not be realized at all the times that the function exists.</obo:IAO_0000116>
<obo:IAO_0000118 xml:lang="en">function_of</obo:IAO_0000118>
<obo:IAO_0000118 xml:lang="en">is function of</obo:IAO_0000118>
<rdfs:comment>This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020.</rdfs:comment>
<rdfs:label xml:lang="en">function of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0000080 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000080">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000086"/>
<obo:IAO_0000112 xml:lang="en">this red color is a quality of this apple</obo:IAO_0000112>
<obo:IAO_0000115 xml:lang="en">a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">A quality inheres in its bearer at all times for which the quality exists.</obo:IAO_0000116>
<obo:IAO_0000118 xml:lang="en">is quality of</obo:IAO_0000118>
<obo:IAO_0000118 xml:lang="en">quality_of</obo:IAO_0000118>
<rdfs:comment>This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020.</rdfs:comment>
<rdfs:label xml:lang="en">quality of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0000081 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000081">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<obo:IAO_0000112 xml:lang="en">this investigator role is a role of this person</obo:IAO_0000112>
<obo:IAO_0000115 xml:lang="en">a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">A role inheres in its bearer at all times for which the role exists, however the role need not be realized at all the times that the role exists.</obo:IAO_0000116>
<obo:IAO_0000118 xml:lang="en">is role of</obo:IAO_0000118>
<obo:IAO_0000118 xml:lang="en">role_of</obo:IAO_0000118>
<rdfs:comment>This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020.</rdfs:comment>
<rdfs:label xml:lang="en">role of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0000085 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000085">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000053"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
<obo:IAO_0000112 xml:lang="en">this enzyme has function this catalysis function (more colloquially: this enzyme has this catalysis function)</obo:IAO_0000112>
<obo:IAO_0000115 xml:lang="en">a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">A bearer can have many functions, and its functions can exist for different periods of time, but none of its functions can exist when the bearer does not exist. A function need not be realized at all the times that the function exists.</obo:IAO_0000116>
<obo:IAO_0000118 xml:lang="en">has_function</obo:IAO_0000118>
<rdfs:label xml:lang="en">has function</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0000086 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000086">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000053"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000019"/>
<obo:IAO_0000112 xml:lang="en">this apple has quality this red color</obo:IAO_0000112>
<obo:IAO_0000115 xml:lang="en">a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">A bearer can have many qualities, and its qualities can exist for different periods of time, but none of its qualities can exist when the bearer does not exist.</obo:IAO_0000116>
<obo:IAO_0000118 xml:lang="en">has_quality</obo:IAO_0000118>
<rdfs:label xml:lang="en">has quality</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0000087 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000087">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000053"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<obo:IAO_0000112 xml:lang="en">this person has role this investigator role (more colloquially: this person has this role of investigator)</obo:IAO_0000112>
<obo:IAO_0000115 xml:lang="en">a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">A bearer can have many roles, and its roles can exist for different periods of time, but none of its roles can exist when the bearer does not exist. A role need not be realized at all the times that the role exists.</obo:IAO_0000116>
<obo:IAO_0000118 xml:lang="en">has_role</obo:IAO_0000118>
<rdfs:label xml:lang="en">has role</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0000091 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000091">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000053"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000092"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000016"/>
<obo:IAO_0000115 xml:lang="en">a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence</obo:IAO_0000115>
<rdfs:label xml:lang="en">has disposition</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0000092 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000092">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<rdfs:comment>This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020.</rdfs:comment>
<rdfs:label xml:lang="en">disposition of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0001000 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0001000">
<rdfs:subPropertyOf rdf:resource="http://www.w3.org/2002/07/owl#topObjectProperty"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0001001"/>
<obo:IAO_0000111>derives from</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">this cell derives from this parent cell (cell division)</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">this nucleus derives from this parent nucleus (nuclear division)</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">a relation between two distinct material entities, the new entity and the old entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">This is a very general relation. More specific relations are preferred when applicable, such as 'directly develops from'.</obo:IAO_0000116>
<obo:IAO_0000118 xml:lang="en">derives_from</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
<rdfs:label xml:lang="en">derives from</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0001001 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0001001">
<obo:IAO_0000112 xml:lang="en">this parent cell derives into this cell (cell division)</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">this parent nucleus derives into this nucleus (nuclear division)</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">a relation between two distinct material entities, the old entity and the new entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">This is a very general relation. More specific relations are preferred when applicable, such as 'directly develops into'. To avoid making statements about a future that may not come to pass, it is often better to use the backward-looking 'derives from' rather than the forward-looking 'derives into'.</obo:IAO_0000116>
<obo:IAO_0000118 xml:lang="en">derives_into</obo:IAO_0000118>
<rdfs:label xml:lang="en">derives into</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0001015 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0001015">
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<obo:IAO_0000111 xml:lang="en">is location of</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">my head is the location of my brain</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">this cage is the location of this rat</obo:IAO_0000112>
<obo:IAO_0000115 xml:lang="en">a relation between two independent continuants, the location and the target, in which the target is entirely within the location</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">Most location relations will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/</obo:IAO_0000116>
<obo:IAO_0000118 xml:lang="en">location_of</obo:IAO_0000118>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<rdfs:label xml:lang="en">location of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0001025 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0001025">
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
<rdfs:domain>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000004"/>
<owl:Class>
<owl:complementOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000006"/>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</rdfs:domain>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
<rdfs:range>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000004"/>
<owl:Class>
<owl:complementOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000006"/>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</rdfs:range>
<obo:IAO_0000111 xml:lang="en">located in</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">my brain is located in my head</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">this rat is located in this cage</obo:IAO_0000112>
<obo:IAO_0000115 xml:lang="en">a relation between two independent continuants, the target and the location, in which the target is entirely within the location</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">Location as a relation between instances: The primitive instance-level relation c located_in r at t reflects the fact that each continuant is at any given time associated with exactly one spatial region, namely its exact location. Following we can use this relation to define a further instance-level location relation - not between a continuant and the region which it exactly occupies, but rather between one continuant and another. c is located in c1, in this sense, whenever the spatial region occupied by c is part_of the spatial region occupied by c1. Note that this relation comprehends both the relation of exact location between one continuant and another which obtains when r and r1 are identical (for example, when a portion of fluid exactly fills a cavity), as well as those sorts of inexact location relations which obtain, for example, between brain and head or between ovum and uterus</obo:IAO_0000116>
<obo:IAO_0000116 xml:lang="en">Most location relations will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/</obo:IAO_0000116>
<obo:IAO_0000118 xml:lang="en">located_in</obo:IAO_0000118>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<terms:source>http://www.obofoundry.org/ro/#OBO_REL:located_in</terms:source>
<rdfs:label xml:lang="en">located in</rdfs:label>
</owl:ObjectProperty>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
<owl:annotatedProperty rdf:resource="http://www.w3.org/2000/01/rdf-schema#domain"/>
<owl:annotatedTarget rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
<obo:IAO_0000116>This is redundant with the more specific 'independent and not spatial region' constraint. We leave in the redundant axiom for use with reasoners that do not use negation.</obo:IAO_0000116>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
<owl:annotatedProperty rdf:resource="http://www.w3.org/2000/01/rdf-schema#range"/>
<owl:annotatedTarget rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
<obo:IAO_0000116>This is redundant with the more specific 'independent and not spatial region' constraint. We leave in the redundant axiom for use with reasoners that do not use negation.</obo:IAO_0000116>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/RO_0002000 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002000">
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002002"/>
<obo:IAO_0000112 xml:lang="en">the surface of my skin is a 2D boundary of my body</obo:IAO_0000112>
<obo:IAO_0000115 xml:lang="en">a relation between a 2D immaterial entity (the boundary) and a material entity, in which the boundary delimits the material entity</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">A 2D boundary may have holes and gaps, but it must be a single connected entity, not an aggregate of several disconnected parts.</obo:IAO_0000116>
<obo:IAO_0000116 xml:lang="en">Although the boundary is two-dimensional, it exists in three-dimensional space and thus has a 3D shape.</obo:IAO_0000116>
<obo:IAO_0000118 xml:lang="en">2D_boundary_of</obo:IAO_0000118>
<obo:IAO_0000118 xml:lang="en">boundary of</obo:IAO_0000118>
<obo:IAO_0000118 xml:lang="en">is 2D boundary of</obo:IAO_0000118>
<obo:IAO_0000118 xml:lang="en">is boundary of</obo:IAO_0000118>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<rdfs:label xml:lang="en">2D boundary of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002002 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002002">
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000141"/>
<obo:IAO_0000112 xml:lang="en">my body has 2D boundary the surface of my skin</obo:IAO_0000112>
<obo:IAO_0000115 xml:lang="en">a relation between a material entity and a 2D immaterial entity (the boundary), in which the boundary delimits the material entity</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">A 2D boundary may have holes and gaps, but it must be a single connected entity, not an aggregate of several disconnected parts.</obo:IAO_0000116>
<obo:IAO_0000116 xml:lang="en">Although the boundary is two-dimensional, it exists in three-dimensional space and thus has a 3D shape.</obo:IAO_0000116>
<obo:IAO_0000118 xml:lang="en">has boundary</obo:IAO_0000118>
<obo:IAO_0000118 xml:lang="en">has_2D_boundary</obo:IAO_0000118>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<rdfs:label xml:lang="en">has 2D boundary</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002087 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002087">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000062"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002090"/>
<obo:IAO_0000117>David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000118>starts_at_end_of</obo:IAO_0000118>
<rdfs:comment xml:lang="en">X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y)</rdfs:comment>
<rdfs:label xml:lang="en">immediately preceded by</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002090 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002090">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000063"/>
<obo:IAO_0000117>David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000118>ends_at_start_of</obo:IAO_0000118>
<obo:IAO_0000118>meets</obo:IAO_0000118>
<rdfs:comment xml:lang="en">X immediately_precedes_Y iff: end(X) simultaneous_with start(Y)</rdfs:comment>
<rdfs:label xml:lang="en">immediately precedes</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002180 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002180">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.</obo:IAO_0000115>
<obo:IAO_0000116>The definition of 'has component' is still under discussion. The challenge is in providing a definition that does not imply transitivity.</obo:IAO_0000116>
<obo:IAO_0000232 xml:lang="en">For use in recording has_part with a cardinality constraint, because OWL does not permit cardinality constraints to be used in combination with transitive object properties. In situations where you would want to say something like 'has part exactly 5 digit, you would instead use has_component exactly 5 digit.</obo:IAO_0000232>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<rdfs:label xml:lang="en">has component</rdfs:label>
<rdfs:seeAlso rdf:resource="http://ontologydesignpatterns.org/wiki/Submissions:Componency"/>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002215 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002215">
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
<obo:IAO_0000115>A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process.</obo:IAO_0000115>
<obo:IAO_0000118>has function realized in</obo:IAO_0000118>
<rdfs:label>capable of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002219 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002219">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002220"/>
<obo:IAO_0000111>surrounded by</obo:IAO_0000111>
<obo:IAO_0000115>x surrounded_by y if and only if x is adjacent to y and for every region r that is adjacent to x, r overlaps y</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
<rdfs:label xml:lang="en">surrounded by</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002220 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002220">
<rdfs:label>adjacent to</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002222 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002222">
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000116>move to BFO?</obo:IAO_0000116>
<obo:IAO_0000119>Allen</obo:IAO_0000119>
<rdfs:comment>A relation that holds between two occurrents. This is a grouping relation that collects together all the Allen relations.</rdfs:comment>
<rdfs:label xml:lang="en">temporal relation</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002223 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002223">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002222"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>inverse of starts with</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119>Allen</obo:IAO_0000119>
<rdfs:label xml:lang="en">starts</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002350 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002350">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002351"/>
<obo:IAO_0000112>An organism that is a member of a population of organisms</obo:IAO_0000112>
<obo:IAO_0000115>is member of is a mereological relation between a item and a collection.</obo:IAO_0000115>
<obo:IAO_0000118>is member of</obo:IAO_0000118>
<obo:IAO_0000118>member part of</obo:IAO_0000118>
<obo:IAO_0000119>SIO</obo:IAO_0000119>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<rdfs:label xml:lang="en">member of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002351 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002351">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#IrreflexiveProperty"/>
<obo:IAO_0000115>has member is a mereological relation between a collection and an item.</obo:IAO_0000115>
<obo:IAO_0000119>SIO</obo:IAO_0000119>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<rdfs:label xml:lang="en">has member</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0004096 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0004096">
<rdfs:comment>DEPRECATED This relation is similar to but different in important respects to the characteristic-of relation. See comments on that relation for more information.</rdfs:comment>
<rdfs:label xml:lang="en">DEPRECATED inheres in</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0004097 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0004097">
<rdfs:label xml:lang="en">DEPRECATED bearer of</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:ObjectProperty>
<!-- http://www.geneontology.org/formats/oboInOwl#ObsoleteProperty -->
<owl:ObjectProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#ObsoleteProperty"/>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Data properties
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!-- http://purl.obolibrary.org/obo/IAO_0000004 -->
<owl:DatatypeProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000004">
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#FunctionalProperty"/>
<obo:IAO_0000111 xml:lang="en">has measurement value</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">has measurement value</rdfs:label>
</owl:DatatypeProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0000292 -->
<owl:DatatypeProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000292">
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/OBI_0200140"/>
<obo:IAO_0000111>has_feature_value</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">has_feature_value datatype property is used to describe the feature values which the feature class can contain, for example has_base can have feature values of nonNegativeInteger values.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<rdfs:label xml:lang="en">has_feature_value</rdfs:label>
</owl:DatatypeProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0001937 -->
<owl:DatatypeProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0001937">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002135"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/OBI_0001933"/>
<rdfs:range rdf:resource="http://www.w3.org/2002/07/owl#real"/>
<obo:IAO_0000111>has specified numeric value</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A relation between a value specification and a number that quantifies it.</obo:IAO_0000115>
<obo:IAO_0000116>A range of 'real' might be better than 'float'. For now we follow 'has measurement value' until we can consider technical issues with SPARQL queries and reasoning.</obo:IAO_0000116>
<obo:IAO_0000117>PERSON: James A. Overton</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>has specified numeric value</rdfs:label>
</owl:DatatypeProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0002135 -->
<owl:DatatypeProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0002135">
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/OBI_0001933"/>
<obo:IAO_0000111 xml:lang="en">has specified value</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A relation between a value specification and a literal.</obo:IAO_0000115>
<obo:IAO_0000116>This is not an RDF/OWL object property. It is intended to link a value found in e.g. a database column of 'M' (the literal) to an instance of a value specification class, which can then be linked to indicate that this is about the biological gender of a human subject.</obo:IAO_0000116>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">has specified value</rdfs:label>
</owl:DatatypeProperty>
<!-- http://purl.obolibrary.org/obo/OBI_0002815 -->
<owl:DatatypeProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0002815">
<obo:IAO_0000111 xml:lang="en">has representation</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">12th arrondissement of Paris</obo:IAO_0000112>
<obo:IAO_0000112>20g</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">I feel sick to my stomach every Tuesday</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">'has representation' is a data property that attaches between an information content entity and a value that contains linguistically or computationally coded text.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">Further processing may enable the value to be represented in a component data structure such as an OBI value specification.</obo:IAO_0000116>
<obo:IAO_0000117>Damion Dooley</obo:IAO_0000117>
<obo:IAO_0000117>Mark Miller</obo:IAO_0000117>
<dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2019-07-14T07:05:50Z</dc:date>
<rdfs:label xml:lang="en">has representation</rdfs:label>
</owl:DatatypeProperty>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Classes
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!-- http://purl.obolibrary.org/obo/BFO_0000001 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000001">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<obo:BFO_0000179>entity</obo:BFO_0000179>
<obo:BFO_0000180>Entity</obo:BFO_0000180>
<obo:IAO_0000112 xml:lang="en">Julius Caesar</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">Verdi’s Requiem</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the Second World War</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">your body mass index</obo:IAO_0000112>
<obo:IAO_0000116 xml:lang="en">BFO 2 Reference: In all areas of empirical inquiry we encounter general terms of two sorts. First are general terms which refer to universals or types:animaltuberculosissurgical procedurediseaseSecond, are general terms used to refer to groups of entities which instantiate a given universal but do not correspond to the extension of any subuniversal of that universal because there is nothing intrinsic to the entities in question by virtue of which they – and only they – are counted as belonging to the given group. Examples are: animal purchased by the Emperortuberculosis diagnosed on a Wednesdaysurgical procedure performed on a patient from Stockholmperson identified as candidate for clinical trial #2056-555person who is signatory of Form 656-PPVpainting by Leonardo da VinciSuch terms, which represent what are called ‘specializations’ in [81</obo:IAO_0000116>
<obo:IAO_0000116 xml:lang="en">Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf</obo:IAO_0000116>
<obo:IAO_0000600 xml:lang="en">An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001])</obo:IAO_0000600>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
<rdfs:label xml:lang="en">entity</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000001"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000116"/>
<owl:annotatedTarget xml:lang="en">Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/0000004"/>
<rdfs:comment>per discussion with Barry Smith</rdfs:comment>
<rdfs:seeAlso rdf:resource="http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000001"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
<owl:annotatedTarget xml:lang="en">An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/001-001"/>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/BFO_0000002 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000002">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000001"/>
<owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
<owl:disjointWith>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
</owl:Restriction>
</owl:disjointWith>
<obo:BFO_0000179>continuant</obo:BFO_0000179>
<obo:BFO_0000180>Continuant</obo:BFO_0000180>
<obo:IAO_0000115 xml:lang="en">An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">BFO 2 Reference: Continuant entities are entities which can be sliced to yield parts only along the spatial dimension, yielding for example the parts of your table which we call its legs, its top, its nails. ‘My desk stretches from the window to the door. It has spatial parts, and can be sliced (in space) in two. With respect to time, however, a thing is a continuant.’ [60, p. 240</obo:IAO_0000116>
<obo:IAO_0000116 xml:lang="en">Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants</obo:IAO_0000116>
<obo:IAO_0000600 xml:lang="en">A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002])</obo:IAO_0000600>
<obo:IAO_0000601 xml:lang="en">if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001])</obo:IAO_0000601>
<obo:IAO_0000601 xml:lang="en">if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002])</obo:IAO_0000601>
<obo:IAO_0000601 xml:lang="en">if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002])</obo:IAO_0000601>
<obo:IAO_0000602>(forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002] </obo:IAO_0000602>
<obo:IAO_0000602>(forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001] </obo:IAO_0000602>
<obo:IAO_0000602>(forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002] </obo:IAO_0000602>
<obo:IAO_0000602>(forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002] </obo:IAO_0000602>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
<rdfs:label xml:lang="en">continuant</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000116"/>
<owl:annotatedTarget xml:lang="en">Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/0000007"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
<owl:annotatedTarget xml:lang="en">A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/008-002"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
<owl:annotatedTarget xml:lang="en">if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/126-001"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
<owl:annotatedTarget xml:lang="en">if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/009-002"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
<owl:annotatedTarget xml:lang="en">if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/011-002"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/009-002"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/126-001"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/008-002"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/011-002"/>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/BFO_0000003 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000003">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000001"/>
<owl:disjointWith>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
</owl:Restriction>
</owl:disjointWith>
<obo:BFO_0000179>occurrent</obo:BFO_0000179>
<obo:BFO_0000180>Occurrent</obo:BFO_0000180>
<obo:IAO_0000115 xml:lang="en">An entity that has temporal parts and that happens, unfolds or develops through time.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">BFO 2 Reference: every occurrent that is not a temporal or spatiotemporal region is s-dependent on some independent continuant that is not a spatial region</obo:IAO_0000116>
<obo:IAO_0000116 xml:lang="en">BFO 2 Reference: s-dependence obtains between every process and its participants in the sense that, as a matter of necessity, this process could not have existed unless these or those participants existed also. A process may have a succession of participants at different phases of its unfolding. Thus there may be different players on the field at different times during the course of a football game; but the process which is the entire game s-depends_on all of these players nonetheless. Some temporal parts of this process will s-depend_on on only some of the players.</obo:IAO_0000116>
<obo:IAO_0000116 xml:lang="en">Occurrent doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process.</obo:IAO_0000116>
<obo:IAO_0000116>Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame.</obo:IAO_0000116>
<obo:IAO_0000600 xml:lang="en">An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002])</obo:IAO_0000600>
<obo:IAO_0000601 xml:lang="en">Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001])</obo:IAO_0000601>
<obo:IAO_0000601 xml:lang="en">b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001])</obo:IAO_0000601>
<obo:IAO_0000602>(forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001] </obo:IAO_0000602>
<obo:IAO_0000602>(forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001] </obo:IAO_0000602>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
<rdfs:label xml:lang="en">occurrent</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000116"/>
<owl:annotatedTarget xml:lang="en">Occurrent doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process.</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/0000006"/>
<rdfs:comment>per discussion with Barry Smith</rdfs:comment>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000116"/>
<owl:annotatedTarget>Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame.</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/0000012"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
<owl:annotatedTarget xml:lang="en">An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/077-002"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
<owl:annotatedTarget xml:lang="en">Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/108-001"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
<owl:annotatedTarget xml:lang="en">b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/079-001"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/108-001"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/079-001"/>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/BFO_0000004 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000004">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
<owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000020"/>
<owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000031"/>
<obo:BFO_0000179>ic</obo:BFO_0000179>
<obo:BFO_0000180>IndependentContinuant</obo:BFO_0000180>
<obo:IAO_0000112 xml:lang="en">a chair</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">a heart</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">a leg</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">a molecule</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">a spatial region</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">an atom</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">an orchestra.</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">an organism</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the bottom right portion of a human torso</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the interior of your mouth</obo:IAO_0000112>
<obo:IAO_0000115 xml:lang="en">b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])</obo:IAO_0000115>
<obo:IAO_0000601 xml:lang="en">For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001])</obo:IAO_0000601>
<obo:IAO_0000601 xml:lang="en">For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002])</obo:IAO_0000601>
<obo:IAO_0000602>(forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001] </obo:IAO_0000602>
<obo:IAO_0000602>(forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002] </obo:IAO_0000602>
<obo:IAO_0000602>(iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002] </obo:IAO_0000602>
<rdfs:comment xml:lang="en">A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything.</rdfs:comment>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
<rdfs:label xml:lang="en">independent continuant</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
<owl:annotatedTarget xml:lang="en">b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/017-002"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
<owl:annotatedTarget xml:lang="en">For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/134-001"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
<owl:annotatedTarget xml:lang="en">For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/018-002"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/134-001"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/018-002"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/017-002"/>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/BFO_0000006 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000006">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000141"/>
<obo:BFO_0000179>s-region</obo:BFO_0000179>
<obo:BFO_0000180>SpatialRegion</obo:BFO_0000180>
<obo:IAO_0000116 xml:lang="en">BFO 2 Reference: Spatial regions do not participate in processes.</obo:IAO_0000116>
<obo:IAO_0000116 xml:lang="en">Spatial region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the union of a spatial point and a spatial line that doesn't overlap the point, or two spatial lines that intersect at a single point. In both cases the resultant spatial region is neither 0-dimensional, 1-dimensional, 2-dimensional, or 3-dimensional.</obo:IAO_0000116>
<obo:IAO_0000600 xml:lang="en">A spatial region is a continuant entity that is a continuant_part_of spaceR as defined relative to some frame R. (axiom label in BFO2 Reference: [035-001])</obo:IAO_0000600>
<obo:IAO_0000601 xml:lang="en">All continuant parts of spatial regions are spatial regions. (axiom label in BFO2 Reference: [036-001])</obo:IAO_0000601>
<obo:IAO_0000602>(forall (x y t) (if (and (SpatialRegion x) (continuantPartOfAt y x t)) (SpatialRegion y))) // axiom label in BFO2 CLIF: [036-001] </obo:IAO_0000602>
<obo:IAO_0000602>(forall (x) (if (SpatialRegion x) (Continuant x))) // axiom label in BFO2 CLIF: [035-001] </obo:IAO_0000602>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
<rdfs:label xml:lang="en">spatial region</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000006"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000116"/>
<owl:annotatedTarget xml:lang="en">Spatial region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the union of a spatial point and a spatial line that doesn't overlap the point, or two spatial lines that intersect at a single point. In both cases the resultant spatial region is neither 0-dimensional, 1-dimensional, 2-dimensional, or 3-dimensional.</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/0000002"/>
<rdfs:comment>per discussion with Barry Smith</rdfs:comment>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000006"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
<owl:annotatedTarget xml:lang="en">A spatial region is a continuant entity that is a continuant_part_of spaceR as defined relative to some frame R. (axiom label in BFO2 Reference: [035-001])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/035-001"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000006"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
<owl:annotatedTarget xml:lang="en">All continuant parts of spatial regions are spatial regions. (axiom label in BFO2 Reference: [036-001])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/036-001"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000006"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (x y t) (if (and (SpatialRegion x) (continuantPartOfAt y x t)) (SpatialRegion y))) // axiom label in BFO2 CLIF: [036-001] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/036-001"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000006"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (x) (if (SpatialRegion x) (Continuant x))) // axiom label in BFO2 CLIF: [035-001] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/035-001"/>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/BFO_0000008 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000008">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
<obo:BFO_0000179>t-region</obo:BFO_0000179>
<obo:BFO_0000180>TemporalRegion</obo:BFO_0000180>
<obo:IAO_0000116 xml:lang="en">Temporal region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the mereological sum of a temporal instant and a temporal interval that doesn't overlap the instant. In this case the resultant temporal region is neither 0-dimensional nor 1-dimensional</obo:IAO_0000116>
<obo:IAO_0000600 xml:lang="en">A temporal region is an occurrent entity that is part of time as defined relative to some reference frame. (axiom label in BFO2 Reference: [100-001])</obo:IAO_0000600>
<obo:IAO_0000601 xml:lang="en">All parts of temporal regions are temporal regions. (axiom label in BFO2 Reference: [101-001])</obo:IAO_0000601>
<obo:IAO_0000601 xml:lang="en">Every temporal region t is such that t occupies_temporal_region t. (axiom label in BFO2 Reference: [119-002])</obo:IAO_0000601>
<obo:IAO_0000602>(forall (r) (if (TemporalRegion r) (occupiesTemporalRegion r r))) // axiom label in BFO2 CLIF: [119-002] </obo:IAO_0000602>
<obo:IAO_0000602>(forall (x y) (if (and (TemporalRegion x) (occurrentPartOf y x)) (TemporalRegion y))) // axiom label in BFO2 CLIF: [101-001] </obo:IAO_0000602>
<obo:IAO_0000602>(forall (x) (if (TemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [100-001] </obo:IAO_0000602>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
<rdfs:label xml:lang="en">temporal region</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000008"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000116"/>
<owl:annotatedTarget xml:lang="en">Temporal region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the mereological sum of a temporal instant and a temporal interval that doesn't overlap the instant. In this case the resultant temporal region is neither 0-dimensional nor 1-dimensional</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/0000003"/>
<rdfs:comment>per discussion with Barry Smith</rdfs:comment>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000008"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
<owl:annotatedTarget xml:lang="en">A temporal region is an occurrent entity that is part of time as defined relative to some reference frame. (axiom label in BFO2 Reference: [100-001])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/100-001"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000008"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
<owl:annotatedTarget xml:lang="en">All parts of temporal regions are temporal regions. (axiom label in BFO2 Reference: [101-001])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/101-001"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000008"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
<owl:annotatedTarget xml:lang="en">Every temporal region t is such that t occupies_temporal_region t. (axiom label in BFO2 Reference: [119-002])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/119-002"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000008"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (r) (if (TemporalRegion r) (occupiesTemporalRegion r r))) // axiom label in BFO2 CLIF: [119-002] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/119-002"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000008"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (x y) (if (and (TemporalRegion x) (occurrentPartOf y x)) (TemporalRegion y))) // axiom label in BFO2 CLIF: [101-001] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/101-001"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000008"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (x) (if (TemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [100-001] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/100-001"/>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/BFO_0000009 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000009">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000006"/>
<obo:BFO_0000179>2d-s-region</obo:BFO_0000179>
<obo:BFO_0000180>TwoDimensionalSpatialRegion</obo:BFO_0000180>
<obo:IAO_0000112 xml:lang="en">an infinitely thin plane in space.</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the surface of a sphere-shaped part of space</obo:IAO_0000112>
<obo:IAO_0000600 xml:lang="en">A two-dimensional spatial region is a spatial region that is of two dimensions. (axiom label in BFO2 Reference: [039-001])</obo:IAO_0000600>
<obo:IAO_0000602>(forall (x) (if (TwoDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [039-001] </obo:IAO_0000602>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
<rdfs:label xml:lang="en">two-dimensional spatial region</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000009"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
<owl:annotatedTarget xml:lang="en">A two-dimensional spatial region is a spatial region that is of two dimensions. (axiom label in BFO2 Reference: [039-001])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/039-001"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000009"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (x) (if (TwoDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [039-001] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/039-001"/>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/BFO_0000011 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000011">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
<obo:BFO_0000179>st-region</obo:BFO_0000179>
<obo:BFO_0000180>SpatiotemporalRegion</obo:BFO_0000180>
<obo:IAO_0000112 xml:lang="en">the spatiotemporal region occupied by a human life</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the spatiotemporal region occupied by a process of cellular meiosis.</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the spatiotemporal region occupied by the development of a cancer tumor</obo:IAO_0000112>
<obo:IAO_0000600 xml:lang="en">A spatiotemporal region is an occurrent entity that is part of spacetime. (axiom label in BFO2 Reference: [095-001])</obo:IAO_0000600>
<obo:IAO_0000601 xml:lang="en">All parts of spatiotemporal regions are spatiotemporal regions. (axiom label in BFO2 Reference: [096-001])</obo:IAO_0000601>
<obo:IAO_0000601 xml:lang="en">Each spatiotemporal region at any time t projects_onto some spatial region at t. (axiom label in BFO2 Reference: [099-001])</obo:IAO_0000601>
<obo:IAO_0000601 xml:lang="en">Each spatiotemporal region projects_onto some temporal region. (axiom label in BFO2 Reference: [098-001])</obo:IAO_0000601>
<obo:IAO_0000601 xml:lang="en">Every spatiotemporal region occupies_spatiotemporal_region itself.</obo:IAO_0000601>
<obo:IAO_0000601 xml:lang="en">Every spatiotemporal region s is such that s occupies_spatiotemporal_region s. (axiom label in BFO2 Reference: [107-002])</obo:IAO_0000601>
<obo:IAO_0000602>(forall (r) (if (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion r r))) // axiom label in BFO2 CLIF: [107-002] </obo:IAO_0000602>
<obo:IAO_0000602>(forall (x t) (if (SpatioTemporalRegion x) (exists (y) (and (SpatialRegion y) (spatiallyProjectsOntoAt x y t))))) // axiom label in BFO2 CLIF: [099-001] </obo:IAO_0000602>
<obo:IAO_0000602>(forall (x y) (if (and (SpatioTemporalRegion x) (occurrentPartOf y x)) (SpatioTemporalRegion y))) // axiom label in BFO2 CLIF: [096-001] </obo:IAO_0000602>
<obo:IAO_0000602>(forall (x) (if (SpatioTemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [095-001] </obo:IAO_0000602>
<obo:IAO_0000602>(forall (x) (if (SpatioTemporalRegion x) (exists (y) (and (TemporalRegion y) (temporallyProjectsOnto x y))))) // axiom label in BFO2 CLIF: [098-001] </obo:IAO_0000602>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
<rdfs:label xml:lang="en">spatiotemporal region</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000011"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
<owl:annotatedTarget xml:lang="en">A spatiotemporal region is an occurrent entity that is part of spacetime. (axiom label in BFO2 Reference: [095-001])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/095-001"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000011"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
<owl:annotatedTarget xml:lang="en">All parts of spatiotemporal regions are spatiotemporal regions. (axiom label in BFO2 Reference: [096-001])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/096-001"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000011"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
<owl:annotatedTarget xml:lang="en">Each spatiotemporal region at any time t projects_onto some spatial region at t. (axiom label in BFO2 Reference: [099-001])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/099-001"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000011"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
<owl:annotatedTarget xml:lang="en">Each spatiotemporal region projects_onto some temporal region. (axiom label in BFO2 Reference: [098-001])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/098-001"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000011"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
<owl:annotatedTarget xml:lang="en">Every spatiotemporal region s is such that s occupies_spatiotemporal_region s. (axiom label in BFO2 Reference: [107-002])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/107-002"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000011"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (r) (if (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion r r))) // axiom label in BFO2 CLIF: [107-002] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/107-002"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000011"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (x t) (if (SpatioTemporalRegion x) (exists (y) (and (SpatialRegion y) (spatiallyProjectsOntoAt x y t))))) // axiom label in BFO2 CLIF: [099-001] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/099-001"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000011"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (x y) (if (and (SpatioTemporalRegion x) (occurrentPartOf y x)) (SpatioTemporalRegion y))) // axiom label in BFO2 CLIF: [096-001] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/096-001"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000011"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (x) (if (SpatioTemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [095-001] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/095-001"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000011"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (x) (if (SpatioTemporalRegion x) (exists (y) (and (TemporalRegion y) (temporallyProjectsOnto x y))))) // axiom label in BFO2 CLIF: [098-001] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/098-001"/>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/BFO_0000015 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000015">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
<obo:BFO_0000179>process</obo:BFO_0000179>
<obo:BFO_0000180>Process</obo:BFO_0000180>
<obo:IAO_0000112 xml:lang="en">a process of cell-division, \ a beating of the heart</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">a process of meiosis</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">a process of sleeping</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the course of a disease</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the flight of a bird</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the life of an organism</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">your process of aging.</obo:IAO_0000112>
<obo:IAO_0000115 xml:lang="en">p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">BFO 2 Reference: The realm of occurrents is less pervasively marked by the presence of natural units than is the case in the realm of independent continuants. Thus there is here no counterpart of ‘object’. In BFO 1.0 ‘process’ served as such a counterpart. In BFO 2.0 ‘process’ is, rather, the occurrent counterpart of ‘material entity’. Those natural – as contrasted with engineered, which here means: deliberately executed – units which do exist in the realm of occurrents are typically either parasitic on the existence of natural units on the continuant side, or they are fiat in nature. Thus we can count lives; we can count football games; we can count chemical reactions performed in experiments or in chemical manufacturing. We cannot count the processes taking place, for instance, in an episode of insect mating behavior.Even where natural units are identifiable, for example cycles in a cyclical process such as the beating of a heart or an organism’s sleep/wake cycle, the processes in question form a sequence with no discontinuities (temporal gaps) of the sort that we find for instance where billiard balls or zebrafish or planets are separated by clear spatial gaps. Lives of organisms are process units, but they too unfold in a continuous series from other, prior processes such as fertilization, and they unfold in turn in continuous series of post-life processes such as post-mortem decay. Clear examples of boundaries of processes are almost always of the fiat sort (midnight, a time of death as declared in an operating theater or on a death certificate, the initiation of a state of war)</obo:IAO_0000116>
<obo:IAO_0000602>(iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003] </obo:IAO_0000602>
<rdfs:comment xml:lang="en">An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t.</rdfs:comment>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
<rdfs:label xml:lang="en">process</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
<owl:annotatedTarget xml:lang="en">p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/083-003"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/083-003"/>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/BFO_0000016 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000016">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000017"/>
<owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<obo:BFO_0000179>disposition</obo:BFO_0000179>
<obo:BFO_0000180>Disposition</obo:BFO_0000180>
<obo:IAO_0000112 xml:lang="en">an atom of element X has the disposition to decay to an atom of element Y</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">certain people have a predisposition to colon cancer</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">children are innately disposed to categorize objects in certain ways.</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the cell wall is disposed to filter chemicals in endocytosis and exocytosis</obo:IAO_0000112>
<obo:IAO_0000116 xml:lang="en">BFO 2 Reference: Dispositions exist along a strength continuum. Weaker forms of disposition are realized in only a fraction of triggering cases. These forms occur in a significant number of cases of a similar type.</obo:IAO_0000116>
<obo:IAO_0000600 xml:lang="en">b is a disposition means: b is a realizable entity & b’s bearer is some material entity & b is such that if it ceases to exist, then its bearer is physically changed, & b’s realization occurs when and because this bearer is in some special physical circumstances, & this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002])</obo:IAO_0000600>
<obo:IAO_0000601 xml:lang="en">If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002])</obo:IAO_0000601>
<obo:IAO_0000602>(forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002] </obo:IAO_0000602>
<obo:IAO_0000602>(forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002] </obo:IAO_0000602>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
<rdfs:label xml:lang="en">disposition</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000016"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
<owl:annotatedTarget xml:lang="en">b is a disposition means: b is a realizable entity & b’s bearer is some material entity & b is such that if it ceases to exist, then its bearer is physically changed, & b’s realization occurs when and because this bearer is in some special physical circumstances, & this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/062-002"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000016"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
<owl:annotatedTarget xml:lang="en">If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/063-002"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000016"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/063-002"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000016"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/062-002"/>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/BFO_0000017 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000017">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000020"/>
<owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000019"/>
<obo:BFO_0000179>realizable</obo:BFO_0000179>
<obo:BFO_0000180>RealizableEntity</obo:BFO_0000180>
<obo:IAO_0000112 xml:lang="en">the disposition of this piece of metal to conduct electricity.</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the disposition of your blood to coagulate</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the function of your reproductive organs</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the role of being a doctor</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the role of this boundary to delineate where Utah and Colorado meet</obo:IAO_0000112>
<obo:IAO_0000115 xml:lang="en">A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances.</obo:IAO_0000115>
<obo:IAO_0000600 xml:lang="en">To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002])</obo:IAO_0000600>
<obo:IAO_0000601 xml:lang="en">All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002])</obo:IAO_0000601>
<obo:IAO_0000602>(forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002] </obo:IAO_0000602>
<obo:IAO_0000602>(forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002] </obo:IAO_0000602>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
<rdfs:label xml:lang="en">realizable entity</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000017"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
<owl:annotatedTarget xml:lang="en">To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/058-002"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000017"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
<owl:annotatedTarget xml:lang="en">All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/060-002"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000017"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/060-002"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000017"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/058-002"/>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/BFO_0000018 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000018">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000006"/>
<obo:BFO_0000179>0d-s-region</obo:BFO_0000179>
<obo:BFO_0000180>ZeroDimensionalSpatialRegion</obo:BFO_0000180>
<obo:IAO_0000600 xml:lang="en">A zero-dimensional spatial region is a point in space. (axiom label in BFO2 Reference: [037-001])</obo:IAO_0000600>
<obo:IAO_0000602>(forall (x) (if (ZeroDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [037-001] </obo:IAO_0000602>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
<rdfs:label xml:lang="en">zero-dimensional spatial region</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000018"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
<owl:annotatedTarget xml:lang="en">A zero-dimensional spatial region is a point in space. (axiom label in BFO2 Reference: [037-001])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/037-001"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000018"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (x) (if (ZeroDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [037-001] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/037-001"/>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/BFO_0000019 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000019">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000020"/>
<obo:BFO_0000179>quality</obo:BFO_0000179>
<obo:BFO_0000180>Quality</obo:BFO_0000180>
<obo:IAO_0000112 xml:lang="en">the ambient temperature of this portion of air</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the color of a tomato</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the length of the circumference of your waist</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the mass of this piece of gold.</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the shape of your nose</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the shape of your nostril</obo:IAO_0000112>
<obo:IAO_0000600 xml:lang="en">a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001])</obo:IAO_0000600>
<obo:IAO_0000601 xml:lang="en">If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001])</obo:IAO_0000601>
<obo:IAO_0000602>(forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001] </obo:IAO_0000602>
<obo:IAO_0000602>(forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001] </obo:IAO_0000602>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
<rdfs:label xml:lang="en">quality</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000019"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
<owl:annotatedTarget xml:lang="en">a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/055-001"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000019"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
<owl:annotatedTarget xml:lang="en">If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/105-001"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000019"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/055-001"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000019"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/105-001"/>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/BFO_0000020 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000020">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
<owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000031"/>
<obo:BFO_0000179>sdc</obo:BFO_0000179>
<obo:BFO_0000180>SpecificallyDependentContinuant</obo:BFO_0000180>
<obo:IAO_0000112 xml:lang="en">Reciprocal specifically dependent continuants: the function of this key to open this lock and the mutually dependent disposition of this lock: to be opened by this key</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">of one-sided specifically dependent continuants: the mass of this tomato</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">of relational dependent continuants (multiple bearers): John’s love for Mary, the ownership relation between John and this statue, the relation of authority between John and his subordinates.</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the disposition of this fish to decay</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the function of this heart: to pump blood</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the mutual dependence of proton donors and acceptors in chemical reactions [79</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the mutual dependence of the role predator and the role prey as played by two organisms in a given interaction</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the pink color of a medium rare piece of grilled filet mignon at its center</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the role of being a doctor</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the shape of this hole.</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the smell of this portion of mozzarella</obo:IAO_0000112>
<obo:IAO_0000115 xml:lang="en">b is a relational specifically dependent continuant = Def. b is a specifically dependent continuant and there are n &gt; 1 independent continuants c1, … cn which are not spatial regions are such that for all 1 i &lt; j n, ci and cj share no common parts, are such that for each 1 i n, b s-depends_on ci at every time t during the course of b’s existence (axiom label in BFO2 Reference: [131-004])</obo:IAO_0000115>
<obo:IAO_0000115 xml:lang="en">b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc.</obo:IAO_0000116>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<obo:IAO_0000602>(iff (RelationalSpecificallyDependentContinuant a) (and (SpecificallyDependentContinuant a) (forall (t) (exists (b c) (and (not (SpatialRegion b)) (not (SpatialRegion c)) (not (= b c)) (not (exists (d) (and (continuantPartOfAt d b t) (continuantPartOfAt d c t)))) (specificallyDependsOnAt a b t) (specificallyDependsOnAt a c t)))))) // axiom label in BFO2 CLIF: [131-004] </obo:IAO_0000602>
<obo:IAO_0000602>(iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003] </obo:IAO_0000602>
<rdfs:comment xml:lang="en">A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same.</rdfs:comment>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
<rdfs:label xml:lang="en">specifically dependent continuant</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000020"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000116"/>
<owl:annotatedTarget xml:lang="en">Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc.</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/0000005"/>
<rdfs:comment>per discussion with Barry Smith</rdfs:comment>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000020"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(iff (RelationalSpecificallyDependentContinuant a) (and (SpecificallyDependentContinuant a) (forall (t) (exists (b c) (and (not (SpatialRegion b)) (not (SpatialRegion c)) (not (= b c)) (not (exists (d) (and (continuantPartOfAt d b t) (continuantPartOfAt d c t)))) (specificallyDependsOnAt a b t) (specificallyDependsOnAt a c t)))))) // axiom label in BFO2 CLIF: [131-004] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/131-004"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000020"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/050-003"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000020"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
<owl:annotatedTarget xml:lang="en">b is a relational specifically dependent continuant = Def. b is a specifically dependent continuant and there are n &gt; 1 independent continuants c1, … cn which are not spatial regions are such that for all 1 i &lt; j n, ci and cj share no common parts, are such that for each 1 i n, b s-depends_on ci at every time t during the course of b’s existence (axiom label in BFO2 Reference: [131-004])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/131-004"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000020"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
<owl:annotatedTarget xml:lang="en">b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/050-003"/>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/BFO_0000023 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000023">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000017"/>
<obo:BFO_0000179>role</obo:BFO_0000179>
<obo:BFO_0000180>Role</obo:BFO_0000180>
<obo:IAO_0000112 xml:lang="en">John’s role of husband to Mary is dependent on Mary’s role of wife to John, and both are dependent on the object aggregate comprising John and Mary as member parts joined together through the relational quality of being married.</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the priest role</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the role of a boundary to demarcate two neighboring administrative territories</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the role of a building in serving as a military target</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the role of a stone in marking a property boundary</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the role of subject in a clinical trial</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the student role</obo:IAO_0000112>
<obo:IAO_0000115 xml:lang="en">A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">BFO 2 Reference: One major family of examples of non-rigid universals involves roles, and ontologies developed for corresponding administrative purposes may consist entirely of representatives of entities of this sort. Thus ‘professor’, defined as follows,b instance_of professor at t =Def. there is some c, c instance_of professor role & c inheres_in b at t.denotes a non-rigid universal and so also do ‘nurse’, ‘student’, ‘colonel’, ‘taxpayer’, and so forth. (These terms are all, in the jargon of philosophy, phase sortals.) By using role terms in definitions, we can create a BFO conformant treatment of such entities drawing on the fact that, while an instance of professor may be simultaneously an instance of trade union member, no instance of the type professor role is also (at any time) an instance of the type trade union member role (any more than any instance of the type color is at any time an instance of the type length).If an ontology of employment positions should be defined in terms of roles following the above pattern, this enables the ontology to do justice to the fact that individuals instantiate the corresponding universals – professor, sergeant, nurse – only during certain phases in their lives.</obo:IAO_0000116>
<obo:IAO_0000600 xml:lang="en">b is a role means: b is a realizable entity & b exists because there is some single bearer that is in some special physical, social, or institutional set of circumstances in which this bearer does not have to be& b is not such that, if it ceases to exist, then the physical make-up of the bearer is thereby changed. (axiom label in BFO2 Reference: [061-001])</obo:IAO_0000600>
<obo:IAO_0000602>(forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001] </obo:IAO_0000602>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
<rdfs:label xml:lang="en">role</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
<owl:annotatedTarget xml:lang="en">b is a role means: b is a realizable entity & b exists because there is some single bearer that is in some special physical, social, or institutional set of circumstances in which this bearer does not have to be& b is not such that, if it ceases to exist, then the physical make-up of the bearer is thereby changed. (axiom label in BFO2 Reference: [061-001])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/061-001"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/061-001"/>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/BFO_0000024 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000024">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:BFO_0000179>fiat-object</obo:BFO_0000179>
<obo:BFO_0000180>FiatObjectPart</obo:BFO_0000180>
<obo:IAO_0000112 xml:lang="en">or with divisions drawn by cognitive subjects for practical reasons, such as the division of a cake (before slicing) into (what will become) slices (and thus member parts of an object aggregate). However, this does not mean that fiat object parts are dependent for their existence on divisions or delineations effected by cognitive subjects. If, for example, it is correct to conceive geological layers of the Earth as fiat object parts of the Earth, then even though these layers were first delineated in recent times, still existed long before such delineation and what holds of these layers (for example that the oldest layers are also the lowest layers) did not begin to hold because of our acts of delineation.Treatment of material entity in BFOExamples viewed by some as problematic cases for the trichotomy of fiat object part, object, and object aggregate include: a mussel on (and attached to) a rock, a slime mold, a pizza, a cloud, a galaxy, a railway train with engine and multiple carriages, a clonal stand of quaking aspen, a bacterial community (biofilm), a broken femur. Note that, as Aristotle already clearly recognized, such problematic cases – which lie at or near the penumbra of instances defined by the categories in question – need not invalidate these categories. The existence of grey objects does not prove that there are not objects which are black and objects which are white; the existence of mules does not prove that there are not objects which are donkeys and objects which are horses. It does, however, show that the examples in question need to be addressed carefully in order to show how they can be fitted into the proposed scheme, for example by recognizing additional subdivisions [29</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the FMA:regional parts of an intact human body.</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the Western hemisphere of the Earth</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the division of the brain into regions</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the division of the planet into hemispheres</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the dorsal and ventral surfaces of the body</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the upper and lower lobes of the left lung</obo:IAO_0000112>
<obo:IAO_0000116 xml:lang="en">BFO 2 Reference: Most examples of fiat object parts are associated with theoretically drawn divisions</obo:IAO_0000116>
<obo:IAO_0000600 xml:lang="en">b is a fiat object part = Def. b is a material entity which is such that for all times t, if b exists at t then there is some object c such that b proper continuant_part of c at t and c is demarcated from the remainder of c by a two-dimensional continuant fiat boundary. (axiom label in BFO2 Reference: [027-004])</obo:IAO_0000600>
<obo:IAO_0000602>(forall (x) (if (FiatObjectPart x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y) (and (Object y) (properContinuantPartOfAt x y t)))))))) // axiom label in BFO2 CLIF: [027-004] </obo:IAO_0000602>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
<rdfs:label xml:lang="en">fiat object</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000024"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
<owl:annotatedTarget xml:lang="en">b is a fiat object part = Def. b is a material entity which is such that for all times t, if b exists at t then there is some object c such that b proper continuant_part of c at t and c is demarcated from the remainder of c by a two-dimensional continuant fiat boundary. (axiom label in BFO2 Reference: [027-004])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/027-004"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000024"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (x) (if (FiatObjectPart x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y) (and (Object y) (properContinuantPartOfAt x y t)))))))) // axiom label in BFO2 CLIF: [027-004] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/027-004"/>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/BFO_0000026 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000026">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000006"/>
<obo:BFO_0000179>1d-s-region</obo:BFO_0000179>
<obo:BFO_0000180>OneDimensionalSpatialRegion</obo:BFO_0000180>
<obo:IAO_0000112 xml:lang="en">an edge of a cube-shaped portion of space.</obo:IAO_0000112>
<obo:IAO_0000600 xml:lang="en">A one-dimensional spatial region is a line or aggregate of lines stretching from one point in space to another. (axiom label in BFO2 Reference: [038-001])</obo:IAO_0000600>
<obo:IAO_0000602>(forall (x) (if (OneDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [038-001] </obo:IAO_0000602>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
<rdfs:label xml:lang="en">one-dimensional spatial region</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000026"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
<owl:annotatedTarget xml:lang="en">A one-dimensional spatial region is a line or aggregate of lines stretching from one point in space to another. (axiom label in BFO2 Reference: [038-001])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/038-001"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000026"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (x) (if (OneDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [038-001] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/038-001"/>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/BFO_0000027 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000027">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:BFO_0000179>object-aggregate</obo:BFO_0000179>
<obo:BFO_0000180>ObjectAggregate</obo:BFO_0000180>
<obo:IAO_0000112 xml:lang="en">a collection of cells in a blood biobank.</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">a swarm of bees is an aggregate of members who are linked together through natural bonds</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">a symphony orchestra</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">an organization is an aggregate whose member parts have roles of specific types (for example in a jazz band, a chess club, a football team)</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">defined by fiat: the aggregate of members of an organization</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">defined through physical attachment: the aggregate of atoms in a lump of granite</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">defined through physical containment: the aggregate of molecules of carbon dioxide in a sealed container</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">defined via attributive delimitations such as: the patients in this hospital</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the aggregate of bearings in a constant velocity axle joint</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the aggregate of blood cells in your body</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the nitrogen atoms in the atmosphere</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the restaurants in Palo Alto</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">your collection of Meissen ceramic plates.</obo:IAO_0000112>
<obo:IAO_0000116>An entity a is an object aggregate if and only if there is a mutually exhaustive and pairwise disjoint partition of a into objects </obo:IAO_0000116>
<obo:IAO_0000116 xml:lang="en">BFO 2 Reference: object aggregates may gain and lose parts while remaining numerically identical (one and the same individual) over time. This holds both for aggregates whose membership is determined naturally (the aggregate of cells in your body) and aggregates determined by fiat (a baseball team, a congressional committee).</obo:IAO_0000116>
<obo:IAO_0000119>ISBN:978-3-938793-98-5pp124-158#Thomas Bittner and Barry Smith, 'A Theory of Granular Partitions', in K. Munn and B. Smith (eds.), Applied Ontology: An Introduction, Frankfurt/Lancaster: ontos, 2008, 125-158.</obo:IAO_0000119>
<obo:IAO_0000600 xml:lang="en">b is an object aggregate means: b is a material entity consisting exactly of a plurality of objects as member_parts at all times at which b exists. (axiom label in BFO2 Reference: [025-004])</obo:IAO_0000600>
<obo:IAO_0000602>(forall (x) (if (ObjectAggregate x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y z) (and (Object y) (Object z) (memberPartOfAt y x t) (memberPartOfAt z x t) (not (= y z)))))) (not (exists (w t_1) (and (memberPartOfAt w x t_1) (not (Object w)))))))) // axiom label in BFO2 CLIF: [025-004] </obo:IAO_0000602>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
<rdfs:label xml:lang="en">object aggregate</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000027"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000116"/>
<owl:annotatedTarget>An entity a is an object aggregate if and only if there is a mutually exhaustive and pairwise disjoint partition of a into objects </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/0000011"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000027"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000116"/>
<owl:annotatedTarget>An entity a is an object aggregate if and only if there is a mutually exhaustive and pairwise disjoint partition of a into objects </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/0000301"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000027"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000119"/>
<owl:annotatedTarget>ISBN:978-3-938793-98-5pp124-158#Thomas Bittner and Barry Smith, 'A Theory of Granular Partitions', in K. Munn and B. Smith (eds.), Applied Ontology: An Introduction, Frankfurt/Lancaster: ontos, 2008, 125-158.</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/0000300"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000027"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
<owl:annotatedTarget xml:lang="en">b is an object aggregate means: b is a material entity consisting exactly of a plurality of objects as member_parts at all times at which b exists. (axiom label in BFO2 Reference: [025-004])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/025-004"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000027"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (x) (if (ObjectAggregate x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y z) (and (Object y) (Object z) (memberPartOfAt y x t) (memberPartOfAt z x t) (not (= y z)))))) (not (exists (w t_1) (and (memberPartOfAt w x t_1) (not (Object w)))))))) // axiom label in BFO2 CLIF: [025-004] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/025-004"/>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/BFO_0000028 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000028">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000006"/>
<obo:BFO_0000179>3d-s-region</obo:BFO_0000179>
<obo:BFO_0000180>ThreeDimensionalSpatialRegion</obo:BFO_0000180>
<obo:IAO_0000112 xml:lang="en">a cube-shaped region of space</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">a sphere-shaped region of space,</obo:IAO_0000112>
<obo:IAO_0000600 xml:lang="en">A three-dimensional spatial region is a spatial region that is of three dimensions. (axiom label in BFO2 Reference: [040-001])</obo:IAO_0000600>
<obo:IAO_0000602>(forall (x) (if (ThreeDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [040-001] </obo:IAO_0000602>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
<rdfs:label xml:lang="en">three-dimensional spatial region</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000028"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
<owl:annotatedTarget xml:lang="en">A three-dimensional spatial region is a spatial region that is of three dimensions. (axiom label in BFO2 Reference: [040-001])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/040-001"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000028"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (x) (if (ThreeDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [040-001] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/040-001"/>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/BFO_0000029 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000029">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000141"/>
<obo:BFO_0000179>site</obo:BFO_0000179>
<obo:BFO_0000180>Site</obo:BFO_0000180>
<obo:IAO_0000112 xml:lang="en">Manhattan Canyon)</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">a hole in the interior of a portion of cheese</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">a rabbit hole</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">an air traffic control region defined in the airspace above an airport</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the Grand Canyon</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the Piazza San Marco</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the cockpit of an aircraft</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the hold of a ship</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the interior of a kangaroo pouch</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the interior of the trunk of your car</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the interior of your bedroom</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the interior of your office</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the interior of your refrigerator</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the lumen of your gut</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">your left nostril (a fiat part – the opening – of your left nasal cavity)</obo:IAO_0000112>
<obo:IAO_0000600 xml:lang="en">b is a site means: b is a three-dimensional immaterial entity that is (partially or wholly) bounded by a material entity or it is a three-dimensional immaterial part thereof. (axiom label in BFO2 Reference: [034-002])</obo:IAO_0000600>
<obo:IAO_0000602>(forall (x) (if (Site x) (ImmaterialEntity x))) // axiom label in BFO2 CLIF: [034-002] </obo:IAO_0000602>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
<rdfs:label xml:lang="en">site</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000029"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
<owl:annotatedTarget xml:lang="en">b is a site means: b is a three-dimensional immaterial entity that is (partially or wholly) bounded by a material entity or it is a three-dimensional immaterial part thereof. (axiom label in BFO2 Reference: [034-002])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/034-002"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000029"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (x) (if (Site x) (ImmaterialEntity x))) // axiom label in BFO2 CLIF: [034-002] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/034-002"/>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/BFO_0000030 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000030">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:BFO_0000179>object</obo:BFO_0000179>
<obo:BFO_0000180>Object</obo:BFO_0000180>
<obo:IAO_0000112 xml:lang="en">atom</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">cell</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">cells and organisms</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">engineered artifacts</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">grain of sand</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">molecule</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">organelle</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">organism</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">planet</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">solid portions of matter</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">star</obo:IAO_0000112>
<obo:IAO_0000116 xml:lang="en">BFO 2 Reference: BFO rests on the presupposition that at multiple micro-, meso- and macroscopic scales reality exhibits certain stable, spatially separated or separable material units, combined or combinable into aggregates of various sorts (for example organisms into what are called ‘populations’). Such units play a central role in almost all domains of natural science from particle physics to cosmology. Many scientific laws govern the units in question, employing general terms (such as ‘molecule’ or ‘planet’) referring to the types and subtypes of units, and also to the types and subtypes of the processes through which such units develop and interact. The division of reality into such natural units is at the heart of biological science, as also is the fact that these units may form higher-level units (as cells form multicellular organisms) and that they may also form aggregates of units, for example as cells form portions of tissue and organs form families, herds, breeds, species, and so on. At the same time, the division of certain portions of reality into engineered units (manufactured artifacts) is the basis of modern industrial technology, which rests on the distributed mass production of engineered parts through division of labor and on their assembly into larger, compound units such as cars and laptops. The division of portions of reality into units is one starting point for the phenomenon of counting.</obo:IAO_0000116>
<obo:IAO_0000116 xml:lang="en">BFO 2 Reference: Each object is such that there are entities of which we can assert unproblematically that they lie in its interior, and other entities of which we can assert unproblematically that they lie in its exterior. This may not be so for entities lying at or near the boundary between the interior and exterior. This means that two objects – for example the two cells depicted in Figure 3 – may be such that there are material entities crossing their boundaries which belong determinately to neither cell. Something similar obtains in certain cases of conjoined twins (see below).</obo:IAO_0000116>
<obo:IAO_0000116 xml:lang="en">BFO 2 Reference: To say that b is causally unified means: b is a material entity which is such that its material parts are tied together in such a way that, in environments typical for entities of the type in question,if c, a continuant part of b that is in the interior of b at t, is larger than a certain threshold size (which will be determined differently from case to case, depending on factors such as porosity of external cover) and is moved in space to be at t at a location on the exterior of the spatial region that had been occupied by b at t, then either b’s other parts will be moved in coordinated fashion or b will be damaged (be affected, for example, by breakage or tearing) in the interval between t and t.causal changes in one part of b can have consequences for other parts of b without the mediation of any entity that lies on the exterior of b. Material entities with no proper material parts would satisfy these conditions trivially. Candidate examples of types of causal unity for material entities of more complex sorts are as follows (this is not intended to be an exhaustive list):CU1: Causal unity via physical coveringHere the parts in the interior of the unified entity are combined together causally through a common membrane or other physical covering\. The latter points outwards toward and may serve a protective function in relation to what lies on the exterior of the entity [13, 47</obo:IAO_0000116>
<obo:IAO_0000116 xml:lang="en">BFO 2 Reference: an object is a maximal causally unified material entity</obo:IAO_0000116>
<obo:IAO_0000116 xml:lang="en">BFO 2 Reference: ‘objects’ are sometimes referred to as ‘grains’ [74</obo:IAO_0000116>
<obo:IAO_0000600 xml:lang="en">b is an object means: b is a material entity which manifests causal unity of one or other of the types CUn listed above & is of a type (a material universal) instances of which are maximal relative to this criterion of causal unity. (axiom label in BFO2 Reference: [024-001])</obo:IAO_0000600>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
<rdfs:label xml:lang="en">object</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000030"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
<owl:annotatedTarget xml:lang="en">b is an object means: b is a material entity which manifests causal unity of one or other of the types CUn listed above & is of a type (a material universal) instances of which are maximal relative to this criterion of causal unity. (axiom label in BFO2 Reference: [024-001])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/024-001"/>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/BFO_0000031 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000031">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
<obo:BFO_0000179>gdc</obo:BFO_0000179>
<obo:BFO_0000180>GenericallyDependentContinuant</obo:BFO_0000180>
<obo:IAO_0000112 xml:lang="en">The entries in your database are patterns instantiated as quality instances in your hard drive. The database itself is an aggregate of such patterns. When you create the database you create a particular instance of the generically dependent continuant type database. Each entry in the database is an instance of the generically dependent continuant type IAO: information content entity.</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the pdf file on your laptop, the pdf file that is a copy thereof on my laptop</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the sequence of this protein molecule; the sequence that is a copy thereof in that protein molecule.</obo:IAO_0000112>
<obo:IAO_0000115 xml:lang="en">b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001])</obo:IAO_0000115>
<obo:IAO_0000602>(iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001] </obo:IAO_0000602>
<rdfs:comment xml:lang="en">A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time.</rdfs:comment>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
<rdfs:label xml:lang="en">generically dependent continuant</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000031"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
<owl:annotatedTarget xml:lang="en">b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/074-001"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000031"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/074-001"/>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/BFO_0000034 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000034">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000016"/>
<obo:BFO_0000179>function</obo:BFO_0000179>
<obo:BFO_0000180>Function</obo:BFO_0000180>
<obo:IAO_0000112 xml:lang="en">the function of a hammer to drive in nails</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the function of a heart pacemaker to regulate the beating of a heart through electricity</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the function of amylase in saliva to break down starch into sugar</obo:IAO_0000112>
<obo:IAO_0000116 xml:lang="en">BFO 2 Reference: In the past, we have distinguished two varieties of function, artifactual function and biological function. These are not asserted subtypes of BFO:function however, since the same function – for example: to pump, to transport – can exist both in artifacts and in biological entities. The asserted subtypes of function that would be needed in order to yield a separate monoheirarchy are not artifactual function, biological function, etc., but rather transporting function, pumping function, etc.</obo:IAO_0000116>
<obo:IAO_0000600 xml:lang="en">A function is a disposition that exists in virtue of the bearer’s physical make-up and this physical make-up is something the bearer possesses because it came into being, either through evolution (in the case of natural biological entities) or through intentional design (in the case of artifacts), in order to realize processes of a certain sort. (axiom label in BFO2 Reference: [064-001])</obo:IAO_0000600>
<obo:IAO_0000602>(forall (x) (if (Function x) (Disposition x))) // axiom label in BFO2 CLIF: [064-001] </obo:IAO_0000602>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
<rdfs:label xml:lang="en">function</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
<owl:annotatedTarget xml:lang="en">A function is a disposition that exists in virtue of the bearer’s physical make-up and this physical make-up is something the bearer possesses because it came into being, either through evolution (in the case of natural biological entities) or through intentional design (in the case of artifacts), in order to realize processes of a certain sort. (axiom label in BFO2 Reference: [064-001])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/064-001"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (x) (if (Function x) (Disposition x))) // axiom label in BFO2 CLIF: [064-001] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/064-001"/>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/BFO_0000035 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000035">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
<obo:BFO_0000179>p-boundary</obo:BFO_0000179>
<obo:BFO_0000180>ProcessBoundary</obo:BFO_0000180>
<obo:IAO_0000112 xml:lang="en">the boundary between the 2nd and 3rd year of your life.</obo:IAO_0000112>
<obo:IAO_0000115 xml:lang="en">p is a process boundary =Def. p is a temporal part of a process & p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001])</obo:IAO_0000115>
<obo:IAO_0000601 xml:lang="en">Every process boundary occupies_temporal_region a zero-dimensional temporal region. (axiom label in BFO2 Reference: [085-002])</obo:IAO_0000601>
<obo:IAO_0000602>(forall (x) (if (ProcessBoundary x) (exists (y) (and (ZeroDimensionalTemporalRegion y) (occupiesTemporalRegion x y))))) // axiom label in BFO2 CLIF: [085-002] </obo:IAO_0000602>
<obo:IAO_0000602>(iff (ProcessBoundary a) (exists (p) (and (Process p) (temporalPartOf a p) (not (exists (b) (properTemporalPartOf b a)))))) // axiom label in BFO2 CLIF: [084-001] </obo:IAO_0000602>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
<rdfs:label xml:lang="en">process boundary</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000035"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
<owl:annotatedTarget xml:lang="en">p is a process boundary =Def. p is a temporal part of a process & p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/084-001"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000035"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
<owl:annotatedTarget xml:lang="en">Every process boundary occupies_temporal_region a zero-dimensional temporal region. (axiom label in BFO2 Reference: [085-002])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/085-002"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000035"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (x) (if (ProcessBoundary x) (exists (y) (and (ZeroDimensionalTemporalRegion y) (occupiesTemporalRegion x y))))) // axiom label in BFO2 CLIF: [085-002] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/085-002"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000035"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(iff (ProcessBoundary a) (exists (p) (and (Process p) (temporalPartOf a p) (not (exists (b) (properTemporalPartOf b a)))))) // axiom label in BFO2 CLIF: [084-001] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/084-001"/>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/BFO_0000038 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000038">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000008"/>
<owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000148"/>
<obo:BFO_0000179>1d-t-region</obo:BFO_0000179>
<obo:BFO_0000180>OneDimensionalTemporalRegion</obo:BFO_0000180>
<obo:IAO_0000112 xml:lang="en">the temporal region during which a process occurs.</obo:IAO_0000112>
<obo:IAO_0000116 xml:lang="en">BFO 2 Reference: A temporal interval is a special kind of one-dimensional temporal region, namely one that is self-connected (is without gaps or breaks).</obo:IAO_0000116>
<obo:IAO_0000600 xml:lang="en">A one-dimensional temporal region is a temporal region that is extended. (axiom label in BFO2 Reference: [103-001])</obo:IAO_0000600>
<obo:IAO_0000602>(forall (x) (if (OneDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [103-001] </obo:IAO_0000602>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
<rdfs:label xml:lang="en">one-dimensional temporal region</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000038"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
<owl:annotatedTarget xml:lang="en">A one-dimensional temporal region is a temporal region that is extended. (axiom label in BFO2 Reference: [103-001])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/103-001"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000038"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (x) (if (OneDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [103-001] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/103-001"/>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/BFO_0000040 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000040">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
<owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000141"/>
<obo:BFO_0000179>material</obo:BFO_0000179>
<obo:BFO_0000180>MaterialEntity</obo:BFO_0000180>
<obo:IAO_0000111 xml:lang="en">material entity</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">a flame</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">a forest fire</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">a human being</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">a hurricane</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">a photon</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">a puff of smoke</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">a sea wave</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">a tornado</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">an aggregate of human beings.</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">an energy wave</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">an epidemic</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the undetached arm of a human being</obo:IAO_0000112>
<obo:IAO_0000115 xml:lang="en">An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">BFO 2 Reference: Material entities (continuants) can preserve their identity even while gaining and losing material parts. Continuants are contrasted with occurrents, which unfold themselves in successive temporal parts or phases [60</obo:IAO_0000116>
<obo:IAO_0000116 xml:lang="en">BFO 2 Reference: Object, Fiat Object Part and Object Aggregate are not intended to be exhaustive of Material Entity. Users are invited to propose new subcategories of Material Entity.</obo:IAO_0000116>
<obo:IAO_0000116 xml:lang="en">BFO 2 Reference: ‘Matter’ is intended to encompass both mass and energy (we will address the ontological treatment of portions of energy in a later version of BFO). A portion of matter is anything that includes elementary particles among its proper or improper parts: quarks and leptons, including electrons, as the smallest particles thus far discovered; baryons (including protons and neutrons) at a higher level of granularity; atoms and molecules at still higher levels, forming the cells, organs, organisms and other material entities studied by biologists, the portions of rock studied by geologists, the fossils studied by paleontologists, and so on.Material entities are three-dimensional entities (entities extended in three spatial dimensions), as contrasted with the processes in which they participate, which are four-dimensional entities (entities extended also along the dimension of time).According to the FMA, material entities may have immaterial entities as parts – including the entities identified below as sites; for example the interior (or ‘lumen’) of your small intestine is a part of your body. BFO 2.0 embodies a decision to follow the FMA here.</obo:IAO_0000116>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ido.owl"/>
<obo:IAO_0000600 xml:lang="en">A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002])</obo:IAO_0000600>
<obo:IAO_0000601 xml:lang="en">Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002])</obo:IAO_0000601>
<obo:IAO_0000601 xml:lang="en">every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002])</obo:IAO_0000601>
<obo:IAO_0000602>(forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002] </obo:IAO_0000602>
<obo:IAO_0000602>(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002] </obo:IAO_0000602>
<obo:IAO_0000602>(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002] </obo:IAO_0000602>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
<rdfs:label xml:lang="en">material entity</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
<owl:annotatedTarget xml:lang="en">A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/019-002"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
<owl:annotatedTarget xml:lang="en">Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/020-002"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
<owl:annotatedTarget xml:lang="en">every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/021-002"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/019-002"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/021-002"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/020-002"/>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/BFO_0000140 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000140">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000141"/>
<obo:BFO_0000179>cf-boundary</obo:BFO_0000179>
<obo:BFO_0000180>ContinuantFiatBoundary</obo:BFO_0000180>
<obo:IAO_0000115 xml:lang="en">b is a continuant fiat boundary = Def. b is an immaterial entity that is of zero, one or two dimensions and does not include a spatial region as part. (axiom label in BFO2 Reference: [029-001])</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">BFO 2 Reference: In BFO 1.1 the assumption was made that the external surface of a material entity such as a cell could be treated as if it were a boundary in the mathematical sense. The new document propounds the view that when we talk about external surfaces of material objects in this way then we are talking about something fiat. To be dealt with in a future version: fiat boundaries at different levels of granularity.More generally, the focus in discussion of boundaries in BFO 2.0 is now on fiat boundaries, which means: boundaries for which there is no assumption that they coincide with physical discontinuities. The ontology of boundaries becomes more closely allied with the ontology of regions.</obo:IAO_0000116>
<obo:IAO_0000116 xml:lang="en">BFO 2 Reference: a continuant fiat boundary is a boundary of some material entity (for example: the plane separating the Northern and Southern hemispheres; the North Pole), or it is a boundary of some immaterial entity (for example of some portion of airspace). Three basic kinds of continuant fiat boundary can be distinguished (together with various combination kinds [29</obo:IAO_0000116>
<obo:IAO_0000116 xml:lang="en">Continuant fiat boundary doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the mereological sum of two-dimensional continuant fiat boundary and a one dimensional continuant fiat boundary that doesn't overlap it. The situation is analogous to temporal and spatial regions.</obo:IAO_0000116>
<obo:IAO_0000601 xml:lang="en">Every continuant fiat boundary is located at some spatial region at every time at which it exists</obo:IAO_0000601>
<obo:IAO_0000602>(iff (ContinuantFiatBoundary a) (and (ImmaterialEntity a) (exists (b) (and (or (ZeroDimensionalSpatialRegion b) (OneDimensionalSpatialRegion b) (TwoDimensionalSpatialRegion b)) (forall (t) (locatedInAt a b t)))) (not (exists (c t) (and (SpatialRegion c) (continuantPartOfAt c a t)))))) // axiom label in BFO2 CLIF: [029-001] </obo:IAO_0000602>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
<rdfs:label xml:lang="en">continuant fiat boundary</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000140"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
<owl:annotatedTarget xml:lang="en">b is a continuant fiat boundary = Def. b is an immaterial entity that is of zero, one or two dimensions and does not include a spatial region as part. (axiom label in BFO2 Reference: [029-001])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/029-001"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000140"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000116"/>
<owl:annotatedTarget xml:lang="en">Continuant fiat boundary doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the mereological sum of two-dimensional continuant fiat boundary and a one dimensional continuant fiat boundary that doesn't overlap it. The situation is analogous to temporal and spatial regions.</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/0000008"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000140"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(iff (ContinuantFiatBoundary a) (and (ImmaterialEntity a) (exists (b) (and (or (ZeroDimensionalSpatialRegion b) (OneDimensionalSpatialRegion b) (TwoDimensionalSpatialRegion b)) (forall (t) (locatedInAt a b t)))) (not (exists (c t) (and (SpatialRegion c) (continuantPartOfAt c a t)))))) // axiom label in BFO2 CLIF: [029-001] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/029-001"/>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/BFO_0000141 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000141">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
<obo:BFO_0000179>immaterial</obo:BFO_0000179>
<obo:BFO_0000180>ImmaterialEntity</obo:BFO_0000180>
<obo:IAO_0000116 xml:lang="en">BFO 2 Reference: Immaterial entities are divided into two subgroups:boundaries and sites, which bound, or are demarcated in relation, to material entities, and which can thus change location, shape and size and as their material hosts move or change shape or size (for example: your nasal passage; the hold of a ship; the boundary of Wales (which moves with the rotation of the Earth) [38, 7, 10</obo:IAO_0000116>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
<rdfs:label xml:lang="en">immaterial entity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/BFO_0000142 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000142">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000140"/>
<obo:BFO_0000179>1d-cf-boundary</obo:BFO_0000179>
<obo:BFO_0000180>OneDimensionalContinuantFiatBoundary</obo:BFO_0000180>
<obo:IAO_0000112 xml:lang="en">The Equator</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">all geopolitical boundaries</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">all lines of latitude and longitude</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the line separating the outer surface of the mucosa of the lower lip from the outer surface of the skin of the chin.</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the median sulcus of your tongue</obo:IAO_0000112>
<obo:IAO_0000600 xml:lang="en">a one-dimensional continuant fiat boundary is a continuous fiat line whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [032-001])</obo:IAO_0000600>
<obo:IAO_0000602>(iff (OneDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (OneDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [032-001] </obo:IAO_0000602>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
<rdfs:label xml:lang="en">one-dimensional continuant fiat boundary</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000142"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
<owl:annotatedTarget xml:lang="en">a one-dimensional continuant fiat boundary is a continuous fiat line whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [032-001])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/032-001"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000142"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(iff (OneDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (OneDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [032-001] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/032-001"/>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/BFO_0000144 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000144">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
<owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000182"/>
<obo:BFO_0000179>process-profile</obo:BFO_0000179>
<obo:BFO_0000180>ProcessProfile</obo:BFO_0000180>
<obo:IAO_0000112 xml:lang="en">On a somewhat higher level of complexity are what we shall call rate process profiles, which are the targets of selective abstraction focused not on determinate quality magnitudes plotted over time, but rather on certain ratios between these magnitudes and elapsed times. A speed process profile, for example, is represented by a graph plotting against time the ratio of distance covered per unit of time. Since rates may change, and since such changes, too, may have rates of change, we have to deal here with a hierarchy of process profile universals at successive levels</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">One important sub-family of rate process profiles is illustrated by the beat or frequency profiles of cyclical processes, illustrated by the 60 beats per minute beating process of John’s heart, or the 120 beats per minute drumming process involved in one of John’s performances in a rock band, and so on. Each such process includes what we shall call a beat process profile instance as part, a subtype of rate process profile in which the salient ratio is not distance covered but rather number of beat cycles per unit of time. Each beat process profile instance instantiates the determinable universal beat process profile. But it also instantiates multiple more specialized universals at lower levels of generality, selected from rate process profilebeat process profileregular beat process profile3 bpm beat process profile4 bpm beat process profileirregular beat process profileincreasing beat process profileand so on.In the case of a regular beat process profile, a rate can be assigned in the simplest possible fashion by dividing the number of cycles by the length of the temporal region occupied by the beating process profile as a whole. Irregular process profiles of this sort, for example as identified in the clinic, or in the readings on an aircraft instrument panel, are often of diagnostic significance.</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">The simplest type of process profiles are what we shall call ‘quality process profiles’, which are the process profiles which serve as the foci of the sort of selective abstraction that is involved when measurements are made of changes in single qualities, as illustrated, for example, by process profiles of mass, temperature, aortic pressure, and so on.</obo:IAO_0000112>
<obo:IAO_0000115 xml:lang="en">b is a process_profile =Def. there is some process c such that b process_profile_of c (axiom label in BFO2 Reference: [093-002])</obo:IAO_0000115>
<obo:IAO_0000600 xml:lang="en">b process_profile_of c holds when b proper_occurrent_part_of c& there is some proper_occurrent_part d of c which has no parts in common with b & is mutually dependent on b& is such that b, c and d occupy the same temporal region (axiom label in BFO2 Reference: [094-005])</obo:IAO_0000600>
<obo:IAO_0000602>(forall (x y) (if (processProfileOf x y) (and (properContinuantPartOf x y) (exists (z t) (and (properOccurrentPartOf z y) (TemporalRegion t) (occupiesSpatioTemporalRegion x t) (occupiesSpatioTemporalRegion y t) (occupiesSpatioTemporalRegion z t) (not (exists (w) (and (occurrentPartOf w x) (occurrentPartOf w z))))))))) // axiom label in BFO2 CLIF: [094-005] </obo:IAO_0000602>
<obo:IAO_0000602>(iff (ProcessProfile a) (exists (b) (and (Process b) (processProfileOf a b)))) // axiom label in BFO2 CLIF: [093-002] </obo:IAO_0000602>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
<rdfs:label xml:lang="en">process profile</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000144"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
<owl:annotatedTarget xml:lang="en">b is a process_profile =Def. there is some process c such that b process_profile_of c (axiom label in BFO2 Reference: [093-002])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/093-002"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000144"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
<owl:annotatedTarget xml:lang="en">b process_profile_of c holds when b proper_occurrent_part_of c& there is some proper_occurrent_part d of c which has no parts in common with b & is mutually dependent on b& is such that b, c and d occupy the same temporal region (axiom label in BFO2 Reference: [094-005])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/094-005"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000144"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (x y) (if (processProfileOf x y) (and (properContinuantPartOf x y) (exists (z t) (and (properOccurrentPartOf z y) (TemporalRegion t) (occupiesSpatioTemporalRegion x t) (occupiesSpatioTemporalRegion y t) (occupiesSpatioTemporalRegion z t) (not (exists (w) (and (occurrentPartOf w x) (occurrentPartOf w z))))))))) // axiom label in BFO2 CLIF: [094-005] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/094-005"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000144"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(iff (ProcessProfile a) (exists (b) (and (Process b) (processProfileOf a b)))) // axiom label in BFO2 CLIF: [093-002] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/093-002"/>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/BFO_0000145 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000145">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000019"/>
<obo:BFO_0000179>r-quality</obo:BFO_0000179>
<obo:BFO_0000180>RelationalQuality</obo:BFO_0000180>
<obo:IAO_0000112 xml:lang="en">John’s role of husband to Mary is dependent on Mary’s role of wife to John, and both are dependent on the object aggregate comprising John and Mary as member parts joined together through the relational quality of being married.</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">a marriage bond, an instance of love, an obligation between one person and another.</obo:IAO_0000112>
<obo:IAO_0000115 xml:lang="en">b is a relational quality = Def. for some independent continuants c, d and for some time t: b quality_of c at t & b quality_of d at t. (axiom label in BFO2 Reference: [057-001])</obo:IAO_0000115>
<obo:IAO_0000602>(iff (RelationalQuality a) (exists (b c t) (and (IndependentContinuant b) (IndependentContinuant c) (qualityOfAt a b t) (qualityOfAt a c t)))) // axiom label in BFO2 CLIF: [057-001] </obo:IAO_0000602>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
<rdfs:label xml:lang="en">relational quality</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000145"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
<owl:annotatedTarget xml:lang="en">b is a relational quality = Def. for some independent continuants c, d and for some time t: b quality_of c at t & b quality_of d at t. (axiom label in BFO2 Reference: [057-001])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/057-001"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000145"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(iff (RelationalQuality a) (exists (b c t) (and (IndependentContinuant b) (IndependentContinuant c) (qualityOfAt a b t) (qualityOfAt a c t)))) // axiom label in BFO2 CLIF: [057-001] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/057-001"/>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/BFO_0000146 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000146">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000140"/>
<obo:BFO_0000179>2d-cf-boundary</obo:BFO_0000179>
<obo:BFO_0000180>TwoDimensionalContinuantFiatBoundary</obo:BFO_0000180>
<obo:IAO_0000600 xml:lang="en">a two-dimensional continuant fiat boundary (surface) is a self-connected fiat surface whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [033-001])</obo:IAO_0000600>
<obo:IAO_0000602>(iff (TwoDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (TwoDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [033-001] </obo:IAO_0000602>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
<rdfs:label xml:lang="en">two-dimensional continuant fiat boundary</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000146"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
<owl:annotatedTarget xml:lang="en">a two-dimensional continuant fiat boundary (surface) is a self-connected fiat surface whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [033-001])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/033-001"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000146"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(iff (TwoDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (TwoDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [033-001] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/033-001"/>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/BFO_0000147 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000147">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000140"/>
<obo:BFO_0000179>0d-cf-boundary</obo:BFO_0000179>
<obo:BFO_0000180>ZeroDimensionalContinuantFiatBoundary</obo:BFO_0000180>
<obo:IAO_0000112 xml:lang="en">the geographic North Pole</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the point of origin of some spatial coordinate system.</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the quadripoint where the boundaries of Colorado, Utah, New Mexico, and Arizona meet</obo:IAO_0000112>
<obo:IAO_0000116 xml:lang="en">zero dimension continuant fiat boundaries are not spatial points. Considering the example 'the quadripoint where the boundaries of Colorado, Utah, New Mexico, and Arizona meet' : There are many frames in which that point is zooming through many points in space. Whereas, no matter what the frame, the quadripoint is always in the same relation to the boundaries of Colorado, Utah, New Mexico, and Arizona.</obo:IAO_0000116>
<obo:IAO_0000600 xml:lang="en">a zero-dimensional continuant fiat boundary is a fiat point whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [031-001])</obo:IAO_0000600>
<obo:IAO_0000602>(iff (ZeroDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (ZeroDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [031-001] </obo:IAO_0000602>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
<rdfs:label xml:lang="en">zero-dimensional continuant fiat boundary</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000147"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000116"/>
<owl:annotatedTarget xml:lang="en">zero dimension continuant fiat boundaries are not spatial points. Considering the example 'the quadripoint where the boundaries of Colorado, Utah, New Mexico, and Arizona meet' : There are many frames in which that point is zooming through many points in space. Whereas, no matter what the frame, the quadripoint is always in the same relation to the boundaries of Colorado, Utah, New Mexico, and Arizona.</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/0000001"/>
<rdfs:comment>requested by Melanie Courtot</rdfs:comment>
<rdfs:seeAlso rdf:resource="https://groups.google.com/d/msg/bfo-owl-devel/s9Uug5QmAws/ZDRnpiIi_TUJ"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000147"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
<owl:annotatedTarget xml:lang="en">a zero-dimensional continuant fiat boundary is a fiat point whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [031-001])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/031-001"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000147"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(iff (ZeroDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (ZeroDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [031-001] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/031-001"/>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/BFO_0000148 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000148">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000008"/>
<obo:BFO_0000179>0d-t-region</obo:BFO_0000179>
<obo:BFO_0000180>ZeroDimensionalTemporalRegion</obo:BFO_0000180>
<obo:IAO_0000112 xml:lang="en">a temporal region that is occupied by a process boundary</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">right now</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the moment at which a child is born</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the moment at which a finger is detached in an industrial accident</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">the moment of death.</obo:IAO_0000112>
<obo:IAO_0000118 xml:lang="en">temporal instant.</obo:IAO_0000118>
<obo:IAO_0000600 xml:lang="en">A zero-dimensional temporal region is a temporal region that is without extent. (axiom label in BFO2 Reference: [102-001])</obo:IAO_0000600>
<obo:IAO_0000602>(forall (x) (if (ZeroDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [102-001] </obo:IAO_0000602>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
<rdfs:label xml:lang="en">zero-dimensional temporal region</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000148"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
<owl:annotatedTarget xml:lang="en">A zero-dimensional temporal region is a temporal region that is without extent. (axiom label in BFO2 Reference: [102-001])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/102-001"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000148"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
<owl:annotatedTarget>(forall (x) (if (ZeroDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [102-001] </owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/102-001"/>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/BFO_0000182 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000182">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
<obo:BFO_0000179>history</obo:BFO_0000179>
<obo:BFO_0000180>History</obo:BFO_0000180>
<obo:IAO_0000600 xml:lang="en">A history is a process that is the sum of the totality of processes taking place in the spatiotemporal region occupied by a material entity or site, including processes on the surface of the entity or within the cavities to which it serves as host. (axiom label in BFO2 Reference: [138-001])</obo:IAO_0000600>
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
<rdfs:label xml:lang="en">history</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000182"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
<owl:annotatedTarget xml:lang="en">A history is a process that is the sum of the totality of processes taking place in the spatiotemporal region occupied by a material entity or site, including processes on the surface of the entity or within the cavities to which it serves as host. (axiom label in BFO2 Reference: [138-001])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/138-001"/>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/CHEBI_145810 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_145810">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16670"/>
<obo:IAO_0000111>insulin</obo:IAO_0000111>
<obo:IAO_0000115>A peptide hormone which consists of two polypeptide chains, A- and B- chains which are linked together by disulfide bonds. The amino acid sequence of insulin varies across species and certain segments of the molecule are highly conserved. In most species, the A chain consists of 21 amino acids and the B chain consists of 30 amino acids. In mammals, insulin is synthesised in the pancreas within the beta cells whereas in certain species of fish, the insulin-producing tissue is uniquely located in separate structures called Brockmann bodies.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>insulin</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_15377 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_15377">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>water</obo:IAO_0000111>
<obo:IAO_0000115>An oxygen hydride consisting of an oxygen atom that is covalently bonded to two hydrogen atoms</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>water</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_15422 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_15422">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>ATP</obo:IAO_0000111>
<obo:IAO_0000115>An adenosine 5'-phosphate in which the 5'-phosphate is a triphosphate group. It is involved in the transportation of chemical energy during metabolic pathways.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>ATP</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_15956 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_15956">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002744"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002743"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>biotin</obo:IAO_0000111>
<obo:IAO_0000115>An organic heterobicyclic compound that consists of 2-oxohexahydro-1H-thieno[3,4-d]imidazole having a valeric acid substituent attached to the tetrahydrothiophene ring. The parent of the class of biotins.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>biotin</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_16113 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_16113">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>cholesterol</obo:IAO_0000111>
<obo:IAO_0000115>A cholestanoid consisting of cholestane having a double bond at the 5,6-position as well as a 3beta-hydroxy group.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>cholesterol</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_16134 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_16134">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>ammonia</obo:IAO_0000111>
<obo:IAO_0000115>An azane that consists of a single nitrogen atom covelently bonded to three hydrogen atoms.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>ammonia</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_16247 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_16247">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>phospholipid</obo:IAO_0000111>
<obo:IAO_0000115>A lipid containing phosphoric acid as a mono- or di-ester. The term encompasses phosphatidic acids and phosphoglycerides.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>phospholipid</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_16301 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_16301">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>nitrite</obo:IAO_0000111>
<obo:IAO_0000115>The nitrogen oxoanion formed by loss of a proton from nitrous acid.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>nitrite</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_16526 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_16526">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>carbon dioxide</obo:IAO_0000111>
<obo:IAO_0000115>A one-carbon compound with formula CO2 in which the carbon is attached to each oxygen atom by a double bond. A colourless, odourless gas under normal conditions, it is produced during respiration by all animals, fungi and microorganisms that depend directly or indirectly on living or decaying plants for food.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>carbon dioxide</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_16670 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_16670">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33839"/>
<obo:IAO_0000111>peptide</obo:IAO_0000111>
<obo:IAO_0000115>Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>peptide</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_166899 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_166899">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33839"/>
<obo:IAO_0000111>globulin type</obo:IAO_0000111>
<obo:IAO_0000115>One of the major classifications of proteins, which may be further divided into the euglobulins and the pseudoglobulins. The former group is insoluble in water but soluble in saline solutions and may be precipitated in water that has been half-saturated with a salt such as ammonium sulfate. The latter group is soluble in water and has properties that resemble those of the true globulins. Globulins are an important source of protein in seed plants and are found in minute amounts in cereals. Globulins found in animal fluids are enzymes, antibodies, and fibrous and contractile proteins usually contained in the blood plasma.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>globulin type</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_16737 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_16737">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>creatinine</obo:IAO_0000111>
<obo:IAO_0000115>A lactam obtained by formal cyclocondensation of creatine. It is a metabolite of creatine.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>creatinine</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_168396 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_168396">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>mycophenolic acid</obo:IAO_0000111>
<obo:IAO_0000115>A member of the class of 2-benzofurans that is 2-benzofuran-1(3H)-one which is substituted at positions 4, 5, 6, and 7 by methyl, methoxy, (2E)-5-carboxy-3-methylpent-2-en-1-yl, and hydroxy groups, respectively. It is an antibiotic produced by Penicillium brevi-compactum, P. stoloniferum, P. echinulatum and related species. An immunosuppressant, it is widely used (partiularly as its sodium salt and as the 2-(morpholin-4-yl)ethyl ester prodrug, mycophenolate mofetil) to prevent tissue rejection following organ transplants and for the treatment of certain autoimmune diseases.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>mycophenolic acid</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_16919 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_16919">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>creatine</obo:IAO_0000111>
<obo:IAO_0000115>A glycine derivative having methyl and amidino groups attached to the nitrogen.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>creatine</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_16990 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_16990">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>bilirubin IXalpha</obo:IAO_0000111>
<obo:IAO_0000115>A member of the class of biladienes that is a linear tetrapyrrole with the dipyrrole units being of both exovinyl and endovinyl type. A product of heme degradation, it is produced in the reticuloendothelial system by the reduction of biliverdin and transported to the liver as a complex with serum albumin.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>bilirubin IXalpha</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_16991 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_16991">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33696"/>
<obo:IAO_0000111>deoxyribonucleic acid</obo:IAO_0000111>
<obo:IAO_0000115>High molecular weight, linear polymers, composed of nucleotides containing deoxyribose and linked by phosphodiester bonds; DNA contain the genetic information of organisms.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>deoxyribonucleic acid</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_17026 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_17026">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>progesterone</obo:IAO_0000111>
<obo:IAO_0000115>A C21-steroid hormone in which a pregnane skeleton carries oxo substituents at positions 3 and 20 and is unsaturated at C(4)-C(5). As a hormone, it is involved in the female menstrual cycle, pregnancy and embryogenesis of humans and other species.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>progesterone</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_17137 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_17137">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>hydrogensulfite</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>hydrogensulfite</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_17230 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_17230">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33709"/>
<obo:IAO_0000111>homocysteine</obo:IAO_0000111>
<obo:IAO_0000115>A sulfur-containing amino acid consisting of a glycine core with a 2-mercaptoethyl side-chain.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>homocysteine</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_17234 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_17234">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>glucose</obo:IAO_0000111>
<obo:IAO_0000115>An aldohexose used as a source of energy and metabolic intermediate.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>glucose</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_17347 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_17347">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>testosterone</obo:IAO_0000111>
<obo:IAO_0000115>An androstanoid having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5..</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>testosterone</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_17423 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_17423">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33839"/>
<obo:IAO_0000111>methemoglobin</obo:IAO_0000111>
<obo:IAO_0000115>A hemoprotein that is the ferric (Fe(3+)) form of hemoglobin.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>methemoglobin</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_17544 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_17544">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>hydrogencarbonate</obo:IAO_0000111>
<obo:IAO_0000115>The carbon oxoanion resulting from the removal of a proton from carbonic acid.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>hydrogencarbonate</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_17650 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_17650">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>cortisol</obo:IAO_0000111>
<obo:IAO_0000115>A 17alpha-hydroxy-C21-steroid that is pregn-4-ene substituted by oxo groups at positions 3 and 20 and hydroxy groups at positions 11, 17 and 21. Cortisol is a corticosteroid hormone or glucocorticoid produced by zona fasciculata of the adrenal cortex, which is a part of the adrenal gland. It is usually referred to as the "stress hormone" as it is involved in response to stress and anxiety, controlled by corticotropin-releasing hormone (CRH). It increases blood pressure and blood sugar, and reduces immune responses.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>cortisol</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_17709 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_17709">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>5'-adenylyl sulfate</obo:IAO_0000111>
<obo:IAO_0000115>An adenosine 5'-phosphate having a sulfo group attached to one the phosphate OH groups.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>5'-adenylyl sulfate</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_17855 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_17855">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>triglyceride</obo:IAO_0000111>
<obo:IAO_0000115>Any glyceride resulting from the condensation of all three hydroxy groups of glycerol (propane-1,2,3-triol) with fatty acids.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>triglyceride</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_17996 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_17996">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>chloride</obo:IAO_0000111>
<obo:IAO_0000115>A halide anion formed when chlorine picks up an electron to form an an anion.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>chloride</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_20067 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_20067">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35366"/>
<obo:IAO_0000111>3-hydroxybutyric acid</obo:IAO_0000111>
<obo:IAO_0000115>A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>3-hydroxybutyric acid</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_22868 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_22868">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>bile salt</obo:IAO_0000111>
<obo:IAO_0000115>A sodium salt of the conjugate of any bile acid with either glycine or taurine.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>bile salt</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_23367 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_23367">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000111>molecular entity</obo:IAO_0000111>
<obo:IAO_0000115>Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">We are assuming that every molecular entity has to be completely connected by chemical bonds. This excludes protein complexes, which are comprised of minimally two separate molecular entities. We will follow up with Chebi to ensure this is their understanding as well</obo:IAO_0000116>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>molecular entity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_23528 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_23528">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>cytochalasin</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>cytochalasin</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_23965 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_23965">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>estradiol</obo:IAO_0000111>
<obo:IAO_0000115>A 3-hydroxy steroid that is estra-1,3,5(10)-triene substituted by hydroxy groups at positions 3 and 17.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>estradiol</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_23995 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_23995">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>N-ethyl-N-nitrosourea</obo:IAO_0000111>
<obo:IAO_0000115>A member of the class of N-nitrosoureas that is urea in which one of the nitrogens is substituted by ethyl and nitroso groups.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>N-ethyl-N-nitrosourea</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_24636 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_24636">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>proton</obo:IAO_0000111>
<obo:IAO_0000115>Nuclear particle of charge number +1, spin 1/2 and rest mass of 1.007276470(12) u.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>proton</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_24875 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_24875">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>iron cation</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>iron cation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_25078 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_25078">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>luciferin</obo:IAO_0000111>
<obo:IAO_0000115>A low-molecular-mass compound present in bioluminescent organisms that emits light when oxidized in presence of enzyme luciferase.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>luciferin</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_2637 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_2637">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>amikacin</obo:IAO_0000111>
<obo:IAO_0000115>An amino cyclitol glycoside that is kanamycin A acylated at the N-1 position by a 4-amino-2-hydroxybutyryl group.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>amikacin</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_26710 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_26710">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>sodium chloride</obo:IAO_0000111>
<obo:IAO_0000115>An inorganic chloride salt having sodium(1+) as the counterion.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>sodium chloride</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_27226 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_27226">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>uric acid</obo:IAO_0000111>
<obo:IAO_0000115>An oxopurine that is the final oxidation product of purine metabolism.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>uric acid</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_27889 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_27889">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>lead(0)</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>lead(0)</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_28001 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_28001">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16670"/>
<obo:IAO_0000111>vancomycin</obo:IAO_0000111>
<obo:IAO_0000115>A complex glycopeptide from Streptomyces orientalis. It inhibits a specific step in the synthesis of the peptidoglycan layer in the Gram-positive bacteria Staphylococcus aureus and Clostridium difficile.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>vancomycin</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_28358 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_28358">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000111>rac-lactic acid</obo:IAO_0000111>
<obo:IAO_0000115>A racemate comprising equimolar amounts of (R)- and (S)-lactic acid.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>rac-lactic acid</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_28619 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_28619">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>acrylamide</obo:IAO_0000111>
<obo:IAO_0000115>A member of the class of acrylamides that results from the formal condensation of acrylic acid with ammonia.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>acrylamide</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_28689 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_28689">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>dehydroepiandrosterone</obo:IAO_0000111>
<obo:IAO_0000115>An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>dehydroepiandrosterone</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_28774 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_28774">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33709"/>
<obo:IAO_0000111>3,3',5'-triiodothyronine</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>3,3',5'-triiodothyronine</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_28864 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_28864">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>tobramycin</obo:IAO_0000111>
<obo:IAO_0000115>A amino cyclitol glycoside that is kanamycin B lacking the 3-hydroxy substituent from the 2,6-diaminoglucose ring.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>tobramycin</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_29101 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_29101">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>sodium(1+)</obo:IAO_0000111>
<obo:IAO_0000115>A monoatomic monocation obtained from sodium.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>sodium(1+)</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_29103 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_29103">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>potassium(1+)</obo:IAO_0000111>
<obo:IAO_0000115>A monoatomic monocation obtained from potassium.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>potassium(1+)</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_29191 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_29191">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>hydroxyl</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>hydroxyl</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_29237 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_29237">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33250"/>
<obo:IAO_0000111>deuterium atom</obo:IAO_0000111>
<obo:IAO_0000115>The stable isotope of hydrogen with relative atomic mass 2.014102 and a natural abundance of 0.0115 atom percent (from Greek deltaepsilonupsilontauepsilonrhoomicronnu, second).</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>deuterium atom</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_30660 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_30660">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33709"/>
<obo:IAO_0000111>thyroxine</obo:IAO_0000111>
<obo:IAO_0000115>An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>thyroxine</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_30682 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_30682">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>ruthenium atom</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>ruthenium atom</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_31624 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_31624">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002744"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002743"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>fluorescein (lactone form)</obo:IAO_0000111>
<obo:IAO_0000115>A xanthene dye that is highly fluorescent, detectable even when present in minute quantities. Used forensically to detect traces of blood, in analytical chemistry as an indicator in silver nitrate titrations and in microscopy.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>fluorescein (lactone form)</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_31642 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_31642">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>gadodiamide hydrate</obo:IAO_0000111>
<obo:IAO_0000115>The hydrate of gadodiamide.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>gadodiamide hydrate</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_31643 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_31643">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>gadoteridol</obo:IAO_0000111>
<obo:IAO_0000115>A non-ionic gadolinium chelate having a macrocyclic tetraamine framework. It is used as a paramagnetic contrast agent in magnetic resonance imaging (MRI).</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>gadoteridol</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_31991 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_31991">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>phenol red</obo:IAO_0000111>
<obo:IAO_0000115>3H-2,1-Benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 4-hydroxyphenyl groups. A pH indicator changing colour from yellow below pH 6.8 to bright pink above pH 8.2, it is commonly used as an indicator in cell cultures and in home swimming pool test kits. It is also used in the (now infrequently performed) phenolsulfonphthalein (PSP) test for estimation of overall blood flow through the kidney.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>phenol red</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_32142 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_32142">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>sodium citrate dihydrate</obo:IAO_0000111>
<obo:IAO_0000115>The dihydrate of trisodium citrate.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>sodium citrate dihydrate</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_32875 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_32875">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>methyl group</obo:IAO_0000111>
<obo:IAO_0000115>An alkyl group that is the univalent group derived from methane by removal of a hydrogen atom.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>methyl group</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_33250 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_33250">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000111>atom</obo:IAO_0000111>
<obo:IAO_0000115>A chemical entity constituting the smallest component of an element having the chemical properties of the element.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>atom</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_33262 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_33262">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>elemental oxygen</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>elemental oxygen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_33321 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_33321">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33250"/>
<obo:IAO_0000111>rare earth metal atom</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>rare earth metal atom</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_33359 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_33359">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>rhodium atom</obo:IAO_0000111>
<obo:IAO_0000115>A cobalt group element atom of atomic number 45.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>rhodium atom</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_33375 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_33375">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>gadolinium atom</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>gadolinium atom</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_33376 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_33376">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>terbium atom</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>terbium atom</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_33696 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_33696">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33839"/>
<obo:IAO_0000111>nucleic acid</obo:IAO_0000111>
<obo:IAO_0000115>A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), D-ribose or 2-deoxy-D-ribose and phosphoric acid.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>nucleic acid</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_33697 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_33697">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33696"/>
<obo:IAO_0000111>ribonucleic acid</obo:IAO_0000111>
<obo:IAO_0000115>High molecular weight, linear polymers, composed of nucleotides containing ribose and linked by phosphodiester bonds; RNA is central to the synthesis of proteins.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>ribonucleic acid</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_33709 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_33709">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>amino acid</obo:IAO_0000111>
<obo:IAO_0000115>A carboxylic acid containing one or more amino groups.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>amino acid</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_33839 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_33839">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>macromolecule</obo:IAO_0000111>
<obo:IAO_0000115>A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.</obo:IAO_0000115>
<obo:IAO_0000118 xml:lang="en">polymer</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>macromolecule</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_35143 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_35143">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33839"/>
<obo:IAO_0000111>hemoglobin</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>hemoglobin</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_35366 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_35366">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>fatty acid</obo:IAO_0000111>
<obo:IAO_0000115>Any aliphatic monocarboxylic acid derived from or contained in esterified form in an animal or vegetable fat, oil or wax. Natural fatty acids commonly have a chain of 4 to 28 carbons (usually unbranched and even-numbered), which may be saturated or unsaturated. By extension, the term is sometimes used to embrace all acyclic aliphatic carboxylic acids.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>fatty acid</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_35729 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_35729">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>gadolinium molecular entity</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>gadolinium molecular entity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_35780 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_35780">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>phosphate ion</obo:IAO_0000111>
<obo:IAO_0000115>A phosphorus oxoanion that is the conjugate base of phosphoric acid.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>phosphate ion</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_37333 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_37333">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>gadodiamide</obo:IAO_0000111>
<obo:IAO_0000115>A non-ionic gadolinium chelate having a macrocyclic triamine framework. It is used as a paramagnetic contrast agent in magnetic resonance imaging (MRI).</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>gadodiamide</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_37445 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_37445">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>folic acids</obo:IAO_0000111>
<obo:IAO_0000115>A group of heterocyclic compounds based on the pteroic acid skeleton conjugated with one or more L-glutamic acid units.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>folic acids</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_37586 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_37586">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>sodium phosphate</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>sodium phosphate</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_37972 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_37972">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33250"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001879"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002743"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>phosphorus-32 atom</obo:IAO_0000111>
<obo:IAO_0000115>The radioactive isotope of phosphorus with relative atomic mass 31.973907 and half-life of 14.26 days.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>phosphorus-32 atom</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_37973 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_37973">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33250"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001879"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002743"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>phosphorus-33 atom</obo:IAO_0000111>
<obo:IAO_0000115>The radioactive isotope of phosphorus with relative atomic mass 32.971725, half-life of 25.34 days and nuclear spin (1)/2.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>phosphorus-33 atom</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_37987 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_37987">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002744"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002743"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>Cy3 dye</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>Cy3 dye</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_37989 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_37989">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002744"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002743"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>Cy5 dye</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>Cy5 dye</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_39025 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_39025">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_6495"/>
<obo:IAO_0000111>high-density lipoprotein</obo:IAO_0000111>
<obo:IAO_0000115>A class of lipoproteins of small size (4-13 nm) and dense (greater than 1.063 g/ml) particles. They are synthesized in the liver without a lipid core, accumulate cholesterol esters from peripheral tissues and transport them to the liver for re-utilization or elimination from the body (the reverse cholesterol transport).</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>high-density lipoprotein</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_39026 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_39026">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_6495"/>
<obo:IAO_0000111>low-density lipoprotein</obo:IAO_0000111>
<obo:IAO_0000115>A class of lipoproteins of small size (18-25 nm) and low density (1.019-1.063 g/ml) particles with a core composed mainly of cholesterol esters and smaller amounts of triglycerides. The surface monolayer consists mostly of phospholipids, a single copy of apolipoprotein B-100, and free cholesterol molecules. The main function of LDL is to transport cholesterol and cholesterol esters from the liver. Excessive levels are associated with cardiovascular disease.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>low-density lipoprotein</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_39027 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_39027">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_6495"/>
<obo:IAO_0000111>very-low-density lipoprotein</obo:IAO_0000111>
<obo:IAO_0000115>A class of lipoproteins of large size (30-80 nm), very low density (0.93-1.006 g/ml) particles with a core composed mainly of triglycerides and a surface monolayer of phospholipids and cholesterol into which are imbedded the apolipoproteins B, E, and C. VLDL facilitate the transport of endogenously made triglycerides to extrahepatic tissues.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>very-low-density lipoprotein</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_39123 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_39123">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_39124"/>
<obo:IAO_0000111>calcium cation</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>calcium cation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_39124 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_39124">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>calcium ion</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>calcium ion</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_39127 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_39127">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>magnesium cation</obo:IAO_0000111>
<obo:IAO_0000115>Any magnesium ion that is positively charged.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>magnesium cation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_39867 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_39867">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35366"/>
<obo:IAO_0000111>valproic acid</obo:IAO_0000111>
<obo:IAO_0000115>A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>valproic acid</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_42098 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_42098">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002744"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002743"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>digoxigenin</obo:IAO_0000111>
<obo:IAO_0000115>A hydroxy steroid that consists of 5beta-cardanolide having a double bond at the 20(22)-position as well as hydroxy groups at the 3beta-, 12beta- and 14beta-positions. It has been isolated from the plant species of the genus Digitalis.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>digoxigenin</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_42191 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_42191">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>EDTA(4-)</obo:IAO_0000111>
<obo:IAO_0000115>A tetracarboxylic acid anion formed by deprotonation of all four carboxy groups in ethylenediaminetetraacetic acid (EDTA).</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>EDTA(4-)</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_4431 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_4431">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>deoxyribonucleotide</obo:IAO_0000111>
<obo:IAO_0000115>A nucleotide in which the ribose moiety has one or more of its hydroxy groups substituted by hydrogen.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>deoxyribonucleotide</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_4551 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_4551">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>digoxin</obo:IAO_0000111>
<obo:IAO_0000115>A cardenolide glycoside that is digitoxin beta-hydroxylated at C-12. A cardiac glycoside extracted from the foxglove plant, Digitalis lanata, it is used to control ventricular rate in atrial fibrillation and in the management of congestive heart failure with atrial fibrillation, but the margin between toxic and therapeutic doses is small.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>digoxin</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_4705 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_4705">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16991"/>
<obo:IAO_0000111>double-stranded DNA</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>double-stranded DNA</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_472552 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_472552">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>5-bromo-2'-deoxyuridine</obo:IAO_0000111>
<obo:IAO_0000115>A pyrimidine 2'-deoxyribonucleoside compound having 5-bromouracil as the nucleobase.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>5-bromo-2'-deoxyuridine</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_47774 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_47774">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>low-density lipoprotein cholesterol</obo:IAO_0000111>
<obo:IAO_0000115>Cholesterol esters and free cholesterol which are contained in or bound to low-density lipoproteins (LDL).</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>low-density lipoprotein cholesterol</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_47775 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_47775">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>high-density lipoprotein cholesterol</obo:IAO_0000111>
<obo:IAO_0000115>Cholesterol esters and free cholesterol which are contained in or bound to high-density lipoproteins (HDL).</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>high-density lipoprotein cholesterol</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_50076 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_50076">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>chromium-51</obo:IAO_0000111>
<obo:IAO_0000115>A synthetic radioactive isotope of chromium having a half-life of 27.7 days and decaying by electron capture with emission of gamma rays (0.32 MeV); it is used to label red blood cells for measurement of mass or volume, survival time, and sequestration studies, for the diagnosis of gastrointestinal bleeding, and to label platelets to study their survival.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>chromium-51</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_51756 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_51756">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002744"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002743"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>Alexa Fluor 532</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>Alexa Fluor 532</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_51760 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_51760">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002744"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002743"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>Alexa Fluor 546</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>Alexa Fluor 546</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_52673 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_52673">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002744"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002743"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>Alexa Fluor 555</obo:IAO_0000111>
<obo:IAO_0000115>A fluorescent dye of absorption wavelength 555 nm and emission wavelength 565 nm, derived from a 3,6-diaminoxanthene-4,5-disulfate.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>Alexa Fluor 555</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_53526 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_53526">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>tritiated thymidine</obo:IAO_0000111>
<obo:IAO_0000115>Thymidine linked to the radioisotope tritium. Used to label DNA in the study of cellular and viral DNA synthesis.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>tritiated thymidine</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_59050 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_59050">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>dimethyl sulfate</obo:IAO_0000111>
<obo:IAO_0000115>The dimethyl ester of sulfuric acid.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>dimethyl sulfate</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_59051 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_59051">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>diethyl pyrocarbonate</obo:IAO_0000111>
<obo:IAO_0000115>The diethyl ester of dicarbonic acid.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>diethyl pyrocarbonate</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_59052 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_59052">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>1,1-dihydroxy-3-ethoxy-2-butanone</obo:IAO_0000111>
<obo:IAO_0000115>A butanone derivative having two hydroxy substituents at the 1-position and an ethoxy substituent at the 3-position.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>1,1-dihydroxy-3-ethoxy-2-butanone</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_59053 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_59053">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>N-cyclohexyl-N'-(2-(4-morpholinyl)ethyl)carbodiimide</obo:IAO_0000111>
<obo:IAO_0000115>A carbodiimide having cyclcohexyl and 2-(4-morpholinyl)ethyl as the two N-substituents.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>N-cyclohexyl-N'-(2-(4-morpholinyl)ethyl)carbodiimide</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_59054 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_59054">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>N-methylisatoic anhydride</obo:IAO_0000111>
<obo:IAO_0000115>A 3,1-benzoxazin-1,4-dione having an N-methyl substituent.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>N-methylisatoic anhydride</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_59055 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_59055">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>(S)-1-(4-bromoacetamidobenzyl)EDTA</obo:IAO_0000111>
<obo:IAO_0000115>A tetracarboxylic acid consisting of ethylenediaminetetraacetic acid having a 4-bromoacetamidobenzyl group at the C1-position and (S)-configuration.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>(S)-1-(4-bromoacetamidobenzyl)EDTA</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_59056 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_59056">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>EDTA methidiumpropylamide</obo:IAO_0000111>
<obo:IAO_0000115>A combined intercalating and chelating reagent. The iron chelate, prepared by adding Fe(NH4)2(SO4)2, effects random oxidative cleavage of DNA in the presence of O2 and a reducing agent. This activity is useful as a footprinting probe.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>EDTA methidiumpropylamide</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_59424 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_59424">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>bromophenol blue</obo:IAO_0000111>
<obo:IAO_0000115>3H-2,1-Benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 3,5-dibromo-4-hydroxyphenyl groups. It is used as a laboratory indicator, changing from yellow below pH 3 to purple at pH 4.6, and as a size marker for monitoring the progress of agarose gel and polyacrylamide gel electrophoresis. It has also been used as an industrial dye.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>bromophenol blue</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_61057 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_61057">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>tacrolimus hydrate</obo:IAO_0000111>
<obo:IAO_0000115>A hydrate that is the monohydrate form of tacrolimus.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>tacrolimus hydrate</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_61073 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_61073">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>oxygen radical</obo:IAO_0000111>
<obo:IAO_0000115>An inorganic radical in which a free electron resides on one or more oxygen atoms of an oxygen species.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>oxygen radical</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_6495 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_6495">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33839"/>
<obo:IAO_0000111>lipoprotein</obo:IAO_0000111>
<obo:IAO_0000115>A clathrate complex consisting of a lipid enwrapped in a protein host without covalent binding in such a way that the complex has a hydrophilic outer surface consisting of all the protein and the polar ends of any phospholipids.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>lipoprotein</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_81567 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_81567">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33839"/>
<obo:IAO_0000111>thyroid stimulating hormone</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>thyroid stimulating hormone</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_81568 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_81568">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>Luteinizing hormone</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>Luteinizing hormone</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_81569 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_81569">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>Follicle stimulating hormone</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>Follicle stimulating hormone</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_86319 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_86319">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>25-hydroxyvitamin D2</obo:IAO_0000111>
<obo:IAO_0000115>A hydroxycalciol that is vitamin D2 in which the hydrogen at position 25 has been replaced by a hydroxy group.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>25-hydroxyvitamin D2</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHEBI_9754 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_9754">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>tris</obo:IAO_0000111>
<obo:IAO_0000115>A primary amino compound that is tert-butylamine in which one hydrogen attached to each methyl group is replaced by a hydroxy group. A compound widely used as a biological buffer substance in the pH range 7--9; pKa = 8.3 at 20 degreeC; pKa = 7.82 at 37 degreeC.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
<rdfs:label>tris</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHMO_0000087 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHMO_0000087">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHMO_0000102"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001501"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000053"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000018"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000115 xml:lang="en">Any type of light microscopy assay where the specimen can be made to fluoresce (emit energy as visible light) by illuminating it with light of specific wavelengths. These specimens are called fluorophores.</obo:IAO_0000115>
<obo:IAO_0000118>FM</obo:IAO_0000118>
<obo:IAO_0000118>fluorescence imaging</obo:IAO_0000118>
<obo:IAO_0000118>fluorescence microscopic imaging</obo:IAO_0000118>
<obo:IAO_0000119>CHMO</obo:IAO_0000119>
<rdfs:label>fluorescence microscopy assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHMO_0000089 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHMO_0000089">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002119"/>
<obo:IAO_0000115 xml:lang="en">Microscopy where the specimen can be made to fluoresce (emit energy as visible light) by scanning a gas (Ar or Kr) laser spot of specific wavelength over its surface and using a spatial pinhole to eliminate out-of-focus fluorescence.</obo:IAO_0000115>
<obo:IAO_0000118>CLSM</obo:IAO_0000118>
<obo:IAO_0000118>LSCM</obo:IAO_0000118>
<obo:IAO_0000118>confocal fluorescence imaging</obo:IAO_0000118>
<obo:IAO_0000118>confocal laser scanning fluorescence microscopy</obo:IAO_0000118>
<obo:IAO_0000118>confocal laser scanning microscopy</obo:IAO_0000118>
<obo:IAO_0000118>confocal-laser scanning microscopy</obo:IAO_0000118>
<obo:IAO_0000118>fluorescence confocal microscopy</obo:IAO_0000118>
<obo:IAO_0000118>fluorescence confocal scanning laser microscopy</obo:IAO_0000118>
<obo:IAO_0000118>scanning confocal fluorescence microscopy</obo:IAO_0000118>
<obo:IAO_0000119>CHMO</obo:IAO_0000119>
<rdfs:label>confocal fluorescence microscopy assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHMO_0000102 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHMO_0000102">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002119"/>
<obo:IAO_0000115 xml:lang="en">Microscopy where the specimen is illuminated with visible light and a system of lenses is used to produce an image.</obo:IAO_0000115>
<obo:IAO_0000118>OM</obo:IAO_0000118>
<obo:IAO_0000118>light microscopy</obo:IAO_0000118>
<obo:IAO_0000118>optical microscopy</obo:IAO_0000118>
<obo:IAO_0000119>CHMO</obo:IAO_0000119>
<rdfs:label>light microscopy assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CHMO_0000701 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHMO_0000701">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003097"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003540"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0003547"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000115 xml:lang="en">A method where a sample mixture is first separated by liquid chromatography before being ionised and characterised by mass-to-charge ratio and relative abundance using two mass spectrometers in series.</obo:IAO_0000115>
<obo:IAO_0000118>LC-MS-MS</obo:IAO_0000118>
<obo:IAO_0000118>LC-MS/MS</obo:IAO_0000118>
<obo:IAO_0000118>LC-MS2</obo:IAO_0000118>
<obo:IAO_0000118>LC-MSMS</obo:IAO_0000118>
<obo:IAO_0000118>LC/MS/MS</obo:IAO_0000118>
<obo:IAO_0000118>LCMSMS</obo:IAO_0000118>
<obo:IAO_0000118>liquid chromatography tandem mass spectrometry</obo:IAO_0000118>
<obo:IAO_0000118>liquid chromatography tandem mass spectroscopy</obo:IAO_0000118>
<obo:IAO_0000118>liquid chromatography-tandem mass spectroscopy</obo:IAO_0000118>
<obo:IAO_0000119>CHMO</obo:IAO_0000119>
<rdfs:label>liquid chromatography-tandem mass spectrometry</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CLO_0000001 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CLO_0000001">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001866"/>
<rdfs:subClassOf>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001867"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001867"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:unionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf rdf:nodeID="genid176"/>
<obo:IAO_0000111>cell line cell</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A cultured cell that is part of a cell line - a stable and homogeneous population of cells with a common biological origin and propagation history in culture</obo:IAO_0000115>
<obo:IAO_0000115>A cultured cell that is part of a cell line - a stable and homogeneous population of cells with a common biological origin and propagation history in culture
</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/clo.owl"/>
<rdfs:label>cell line cell</rdfs:label>
</owl:Class>
<owl:Restriction rdf:nodeID="genid176">
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000001"/>
</owl:Restriction>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/CLO_0000001"/>
<owl:annotatedProperty rdf:resource="http://www.w3.org/2000/01/rdf-schema#subClassOf"/>
<owl:annotatedTarget rdf:nodeID="genid176"/>
<obo:IAO_0000116>'derives from' is transitive, so even cell line cells created through modification of an existing cell line cell have derived_from some initial primary cultured cell that existed at some point in time.</obo:IAO_0000116>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/CLO_0000018 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CLO_0000018">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CLO_0000001"/>
<obo:IAO_0000111>mortal cell line cell</obo:IAO_0000111>
<obo:IAO_0000115>A cell line cell that is capable of replicating a limited number of times in culture before undergoing senescence.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/clo.owl"/>
<rdfs:label>mortal cell line cell</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CLO_0000019 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CLO_0000019">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CLO_0000001"/>
<obo:IAO_0000111>immortal cell line cell</obo:IAO_0000111>
<obo:IAO_0000115>A cell line cell that is expected to be capable of an unlimited number of divisions, and is thus able to support indefinite propagation in vitro as part of an immortal cell line.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/clo.owl"/>
<rdfs:label>immortal cell line cell</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CLO_0000031 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CLO_0000031">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001905"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CLO_0000001"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CLO_0000001"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">cell line</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A cultured cell population that represents a genetically stable and homogenous population of cultured cells that shares a common propagation history (i.e. has been successively passaged together in culture). </obo:IAO_0000115>
<obo:IAO_0000115>A cultured cell population that represents a genetically stable and homogenous population of cultured cells that shares a common propagation history (i.e. has been successively passaged together in culture).
</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/clo.owl"/>
<rdfs:label xml:lang="en">cell line</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CLO_0009828 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CLO_0009828">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CLO_0000031"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CLO_0000019"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CLO_0000019"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">immortal cell line</obo:IAO_0000111>
<obo:IAO_0000115>A cell line that is expected to be capable of indefinite propagation in an vitro culture.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/clo.owl"/>
<rdfs:label xml:lang="en">immortal cell line</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CLO_0009829 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CLO_0009829">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CLO_0000031"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CLO_0000018"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CLO_0000018"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:qualifiedCardinality rdf:datatype="http://www.w3.org/2001/XMLSchema#nonNegativeInteger">0</owl:qualifiedCardinality>
<owl:onClass rdf:resource="http://purl.obolibrary.org/obo/OBI_0000877"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">mortal cell line</obo:IAO_0000111>
<obo:IAO_0000115>A cell line is able to support only a limited number of passages in vitro.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/clo.owl"/>
<rdfs:label xml:lang="en">mortal cell line</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0000000 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000000">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000111>cell</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PMID:18089833.Cancer Res. 2007 Dec 15;67(24):12018-25. "...Epithelial cells were harvested from histologically confirmed adenocarcinomas .."</obo:IAO_0000112>
<obo:IAO_0000115>A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>cell</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0000001 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000001">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000010"/>
<rdfs:subClassOf>
<owl:Class>
<owl:complementOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600037"/>
</owl:Restriction>
</owl:complementOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Class>
<owl:complementOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000010"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600037"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:complementOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>primary cultured cell</obo:IAO_0000111>
<obo:IAO_0000115>A cultured cell that is freshly isolated from a organismal source, or derives in culture from such a cell prior to the culture being passaged.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>primary cultured cell</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0000003 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000003">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
<obo:IAO_0000111>obsolete native cell</obo:IAO_0000111>
<obo:IAO_0000115>OBSOLETE. A cell that is found in a natural setting, which includes multicellular organism cells 'in vivo' (i.e. part of an organism), and unicellular organisms 'in environment' (i.e. part of a natural environment).</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>obsolete native cell</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0000010 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000010">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000578"/>
<rdfs:subClassOf>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600036"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600036"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:unionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>cultured cell</obo:IAO_0000111>
<obo:IAO_0000115>A cell in vitro that is or has been maintained or propagated as part of a cell culture.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>cultured cell</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0000057 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000057">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
<obo:IAO_0000111>fibroblast</obo:IAO_0000111>
<obo:IAO_0000115>A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>fibroblast</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0000066 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000066">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
<obo:IAO_0000111>epithelial cell</obo:IAO_0000111>
<obo:IAO_0000115>A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>epithelial cell</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0000077 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000077">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000066"/>
<obo:IAO_0000111>mesothelial cell</obo:IAO_0000111>
<obo:IAO_0000115>A flat, squamous-like epithelial cell of mesodermal origin. It forms the mesothelium, which lines the body's serous cavities including the pleural, peritoneal, and pericardial spaces. This cell plays a crucial role in synthesizing and secreting lubricants, such as glycosaminoglycans and surfactants, which minimize friction between adjacent tissues during movement.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>mesothelial cell</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0000084 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000084">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000542"/>
<obo:IAO_0000111>T cell</obo:IAO_0000111>
<obo:IAO_0000115>A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>T cell</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0000097 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000097">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
<obo:IAO_0000111>mast cell</obo:IAO_0000111>
<obo:IAO_0000115>A cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. Progenitors leave bone marrow and mature in connective and mucosal tissue. Mature mast cells are found in all tissues, except the bloodstream. Their phenotype is CD117-high, CD123-negative, CD193-positive, CD200R3-positive, and FceRI-high. Stem-cell factor (KIT-ligand; SCF) is the main controlling signal of their survival and development.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>mast cell</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0000182 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000182">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000066"/>
<obo:IAO_0000111>hepatocyte</obo:IAO_0000111>
<obo:IAO_0000115>The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>hepatocyte</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0000232 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000232">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
<obo:IAO_0000111>erythrocyte</obo:IAO_0000111>
<obo:IAO_0000115>A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>erythrocyte</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0000233 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000233">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
<obo:IAO_0000111>platelet</obo:IAO_0000111>
<obo:IAO_0000115>A non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>platelet</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0000235 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000235">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
<obo:IAO_0000111>macrophage</obo:IAO_0000111>
<obo:IAO_0000115>A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>macrophage</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0000236 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000236">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000542"/>
<obo:IAO_0000111>B cell</obo:IAO_0000111>
<obo:IAO_0000115>A lymphocyte of B lineage that is capable of B cell mediated immunity.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>B cell</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0000451 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000451">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
<obo:IAO_0000111>dendritic cell</obo:IAO_0000111>
<obo:IAO_0000115>A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. These cells are lineage negative (CD3-negative, CD19-negative, CD34-negative, and CD56-negative).</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>dendritic cell</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0000540 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000540">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0002319"/>
<obo:IAO_0000111>neuron</obo:IAO_0000111>
<obo:IAO_0000115>The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>neuron</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0000542 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000542">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000842"/>
<obo:IAO_0000111>lymphocyte</obo:IAO_0000111>
<obo:IAO_0000115>A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>lymphocyte</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0000556 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000556">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
<obo:IAO_0000111>megakaryocyte</obo:IAO_0000111>
<obo:IAO_0000115>A large hematopoietic cell (50 to 100 micron) with a lobated nucleus. Once mature, this cell undergoes multiple rounds of endomitosis and cytoplasmic restructuring to allow platelet formation and release.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>megakaryocyte</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0000558 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000558">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
<obo:IAO_0000111>reticulocyte</obo:IAO_0000111>
<obo:IAO_0000115>An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>reticulocyte</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0000560 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000560">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000775"/>
<obo:IAO_0000111>band form neutrophil</obo:IAO_0000111>
<obo:IAO_0000115>A late neutrophilic metamyelocyte in which the nucleus is indented to more than half the distance to the farthest nuclear margin but in no area being condensed to a single filament. The nucleus is in the form of a curved or coiled band, not having acquired the typical multilobar shape of the mature neutrophil. These cells are fMLP receptor-positive, CD11b-positive, CD35-negative, and CD49d-negative.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>band form neutrophil</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0000562 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000562">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000232"/>
<obo:IAO_0000111>nucleate erythrocyte</obo:IAO_0000111>
<obo:IAO_0000115>An erythrocyte having a nucleus.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>nucleate erythrocyte</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0000576 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000576">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000738"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000842"/>
<obo:IAO_0000111>monocyte</obo:IAO_0000111>
<obo:IAO_0000115>Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>monocyte</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0000578 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000578">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>experimentally modified cell in vitro</obo:IAO_0000111>
<obo:IAO_0000115>A cell in vitro that has undergone physical changes as a consequence of a deliberate and specific experimental procedure.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>experimentally modified cell in vitro</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0000624 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000624">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000789"/>
<obo:IAO_0000111>CD4-positive, alpha-beta T cell</obo:IAO_0000111>
<obo:IAO_0000115>A mature alpha-beta T cell that expresses an alpha-beta T cell receptor and the CD4 coreceptor.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>CD4-positive, alpha-beta T cell</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0000625 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000625">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000789"/>
<obo:IAO_0000111>CD8-positive, alpha-beta T cell</obo:IAO_0000111>
<obo:IAO_0000115>A T cell expressing an alpha-beta T cell receptor and the CD8 coreceptor.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>CD8-positive, alpha-beta T cell</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0000738 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000738">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
<obo:IAO_0000111>leukocyte</obo:IAO_0000111>
<obo:IAO_0000115>An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>leukocyte</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0000767 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000767">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
<obo:IAO_0000111>basophil</obo:IAO_0000111>
<obo:IAO_0000115>Any of the immature or mature forms of a granular leukocyte that in its mature form has an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse, bluish-black granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation. A basophil is CD123-positive, CD193-positive, CD203c-positive, and FceRIa-positive.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>basophil</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0000771 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000771">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000738"/>
<obo:IAO_0000111>eosinophil</obo:IAO_0000111>
<obo:IAO_0000115>Any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin. Eosinophils are CD9-positive, CD191-positive, and CD193-positive.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>eosinophil</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0000775 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000775">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000738"/>
<obo:IAO_0000111>neutrophil</obo:IAO_0000111>
<obo:IAO_0000115>Any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>neutrophil</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0000776 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000776">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000775"/>
<obo:IAO_0000111>immature neutrophil</obo:IAO_0000111>
<obo:IAO_0000115>Any of the immature forms of a neutrophil in which neutrophilic specific granules are present but other phenotypic features of the mature form may be lacking.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>immature neutrophil</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0000786 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000786">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000236"/>
<obo:IAO_0000111>plasma cell</obo:IAO_0000111>
<obo:IAO_0000115>A terminally differentiated, post-mitotic, antibody secreting cell of the B cell lineage with the phenotype CD138-positive, surface immunonoglobulin-negative, and MHC Class II-negative. Plasma cells are oval or round with extensive rough endoplasmic reticulum, a well-developed Golgi apparatus, and a round nucleus having a characteristic cartwheel heterochromatin pattern and are devoted to producing large amounts of immunoglobulin.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>plasma cell</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0000789 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000789">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000084"/>
<obo:IAO_0000111>alpha-beta T cell</obo:IAO_0000111>
<obo:IAO_0000115>A T cell that expresses an alpha-beta T cell receptor complex.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>alpha-beta T cell</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0000794 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000794">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000625"/>
<obo:IAO_0000111>CD8-positive, alpha-beta cytotoxic T cell</obo:IAO_0000111>
<obo:IAO_0000115>A CD8-positive, alpha-beta T cell that is capable of killing target cells in an antigen specific manner with the phenotype perforin-positive and granzyme B-positive.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>CD8-positive, alpha-beta cytotoxic T cell</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0000814 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000814">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000789"/>
<obo:IAO_0000111>mature NK T cell</obo:IAO_0000111>
<obo:IAO_0000115>A mature alpha-beta T cell of a distinct lineage that bears natural killer markers and a T cell receptor specific for a limited set of ligands. NK T cells have activation and regulatory roles particularly early in an immune response.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>mature NK T cell</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0000836 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000836">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
<obo:IAO_0000111>promyelocyte</obo:IAO_0000111>
<obo:IAO_0000115>A precursor in the granulocytic series, being a cell intermediate in development between a myeloblast and myelocyte, that has distinct nucleoli, a nuclear-to-cytoplasmic ratio of 5:1 to 3:1, and containing a few primary cytoplasmic granules. Markers for this cell are fucosyltransferase FUT4-positive, CD33-positive, integrin alpha-M-negative, low affinity immunoglobulin gamma Fc region receptor III-negative, and CD24-negative.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>promyelocyte</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0000842 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000842">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
<obo:IAO_0000111>mononuclear cell</obo:IAO_0000111>
<obo:IAO_0000115>A leukocyte with a single non-segmented nucleus in the mature form.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>mononuclear cell</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0001064 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0001064">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
<obo:IAO_0000111>malignant cell</obo:IAO_0000111>
<obo:IAO_0000115>A neoplastic cell that is capable of entering a surrounding tissue</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>malignant cell</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0002192 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0002192">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
<obo:IAO_0000111>metamyelocyte</obo:IAO_0000111>
<obo:IAO_0000115>A eosinophil precursor in the granulocytic series, being a cell intermediate in development between a myelocyte and a band form cell. The nucleus becomes indented where the indentation is smaller than half the distance to the farthest nuclear margin; chromatin becomes coarse and clumped; specific granules predominate while primary granules are rare.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>metamyelocyte</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0002193 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0002193">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
<obo:IAO_0000111>myelocyte</obo:IAO_0000111>
<obo:IAO_0000115>A cell type that is the first of the maturation stages of the granulocytic leukocytes normally found in the bone marrow. Granules are seen in the cytoplasm. The nuclear material of the myelocyte is denser than that of the myeloblast but lacks a definable membrane. The cell is flat and contains increasing numbers of granules as maturation progresses.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>myelocyte</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0002319 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0002319">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
<obo:IAO_0000111>neural cell</obo:IAO_0000111>
<obo:IAO_0000115>A cell that is part of the nervous system.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>neural cell</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0011114 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0011114">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000775"/>
<obo:IAO_0000111>segmented neutrophil of bone marrow</obo:IAO_0000111>
<obo:IAO_0000115>A segmented neutrophilic cell of the bone marrow reserve pool that expresses CD11b (integrin alpha-M) and high levels of CD16 (low affinity immunoglobulin gamma Fc region receptor III) on its cell surface.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>segmented neutrophil of bone marrow</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_2000001 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_2000001">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000842"/>
<obo:IAO_0000111>peripheral blood mononuclear cell</obo:IAO_0000111>
<obo:IAO_0000115>A leukocyte with a single non-segmented nucleus in the mature form found in the circulatory pool of blood.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label>peripheral blood mononuclear cell</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/COB_0000080 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/COB_0000080">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000111>complex of molecules</obo:IAO_0000111>
<obo:IAO_0000115>A complex of two or more molecular entities that are not covalently bound.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cob.owl"/>
<rdfs:label>complex of molecules</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/ENVO_00001998 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/ENVO_00001998">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000111>soil</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">An environmental material which is primarily composed of minerals, varying proportions of sand, silt, and clay, organic material such as humus, interstitial gases, liquids, and a broad range of resident micro- and macroorganisms.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/envo.owl"/>
<rdfs:label>soil</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/ENVO_00002257 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/ENVO_00002257">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ENVO_00001998"/>
<obo:IAO_0000111>podzol</obo:IAO_0000111>
<obo:IAO_0000115>Podzols are soils with a typically ash-grey upper subsurface horizon, bleached by loss of organic matter and iron oxides, on top of a dark accumulation horizon with brown, reddish or black illuviated humus and/or reddish Fe compounds. Podzols occur in humid areas in the boreal and temperate zones and locally also in the tropics.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/envo.owl"/>
<rdfs:label>podzol</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/ENVO_00010483 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/ENVO_00010483">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000111>environmental material</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A material entity which other material entities in an environmental system are primarily or partially composed of.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/envo.owl"/>
<rdfs:label>environmental material</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GAZ_00000448 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GAZ_00000448">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000029"/>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0000785 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0000785">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0005575"/>
<obo:IAO_0000111>chromatin</obo:IAO_0000111>
<obo:IAO_0000115>The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>chromatin</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0001046 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0001046">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0003674"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0043565"/>
<obo:IAO_0000111>core promoter sequence-specific DNA binding</obo:IAO_0000111>
<obo:IAO_0000115>Binding to a sequence of DNA that is part of a core promoter region. The core promoter is composed of the transcription start site and binding sites for the RNA polymerase and the basal transcription machinery. The transcribed region might be described as a gene, cistron, or operon.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>core promoter sequence-specific DNA binding</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0001047 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0001047">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001588"/>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0001172 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0001172">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0009987"/>
<obo:IAO_0000111>RNA-templated transcription</obo:IAO_0000111>
<obo:IAO_0000115>The synthesis of an RNA transcript from an RNA template.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>RNA-templated transcription</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0001508 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0001508">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>action potential</obo:IAO_0000111>
<obo:IAO_0000115>A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>action potential</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0001788 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0001788">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>antibody-dependent cellular cytotoxicity</obo:IAO_0000111>
<obo:IAO_0000115>Cytolysis of target cells by natural killer cells, eosinophils, neutrophils, monocytes, or macrophages following engagement of antibodies bound to the target cells by Fc receptors on the effector cells.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>antibody-dependent cellular cytotoxicity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0001806 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0001806">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0002524"/>
<obo:IAO_0000111>type IV hypersensitivity</obo:IAO_0000111>
<obo:IAO_0000115>An inflammatory response driven by T cell recognition of processed soluble or cell-associated antigens leading to cytokine release and leukocyte activation.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>type IV hypersensitivity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0001816 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0001816">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>cytokine production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>cytokine production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0001906 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0001906">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>cell killing</obo:IAO_0000111>
<obo:IAO_0000115>Any process in an organism that results in the killing of its own cells or those of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>cell killing</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0001913 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0001913">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001906"/>
<obo:IAO_0000111>T cell mediated cytotoxicity</obo:IAO_0000111>
<obo:IAO_0000115>The directed killing of a target cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>T cell mediated cytotoxicity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0002250 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0002250">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0006955"/>
<obo:IAO_0000111>adaptive immune response</obo:IAO_0000111>
<obo:IAO_0000115>An immune response mediated by cells expressing specific receptors for antigens produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory).</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>adaptive immune response</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0002367 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0002367">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>cytokine production involved in immune response</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus contributing to an immune response, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>cytokine production involved in immune response</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0002390 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0002390">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0002507 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0002507">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>tolerance induction</obo:IAO_0000111>
<obo:IAO_0000115>A process that directly activates any of the steps required for tolerance, a physiologic state in which the immune system does not react destructively against the components of an organism that harbors it or against antigens that are introduced to it.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>tolerance induction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0002514 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0002514">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0002507"/>
<obo:IAO_0000111>B cell tolerance induction</obo:IAO_0000111>
<obo:IAO_0000115>A process involving any mechanism for tolerance induction in B cells.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>B cell tolerance induction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0002517 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0002517">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0002507"/>
<obo:IAO_0000111>T cell tolerance induction</obo:IAO_0000111>
<obo:IAO_0000115>A process involving any mechanism for tolerance induction in T cells.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>T cell tolerance induction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0002524 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0002524">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>hypersensitivity</obo:IAO_0000111>
<obo:IAO_0000115>An inflammatory response to an exogenous environmental antigen or an endogenous antigen initiated by the adaptive immune system.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>hypersensitivity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0002534 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0002534">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>cytokine production involved in inflammatory response</obo:IAO_0000111>
<obo:IAO_0000115>The synthesis or release of a cytokine following a inflammatory stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>cytokine production involved in inflammatory response</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0003094 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0003094">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>glomerular filtration</obo:IAO_0000111>
<obo:IAO_0000115>The process in which plasma is filtered through the glomerular membrane which consists of capillary endothelial cells, the basement membrane, and epithelial cells. The glomerular filtrate is the same as plasma except it has no significant amount of protein.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>glomerular filtration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0003674 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0003674">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
<obo:IAO_0000111>molecular_function</obo:IAO_0000111>
<obo:IAO_0000115>A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>molecular_function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0003823 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0003823">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0003674"/>
<obo:IAO_0000111>antigen binding</obo:IAO_0000111>
<obo:IAO_0000115>Binding to an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen. Antigen binding by an MHC protein complex allows the antigen to be displayed to a T cell or NK cell.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>antigen binding</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0003824 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0003824">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0003674"/>
<obo:IAO_0000111>catalytic activity</obo:IAO_0000111>
<obo:IAO_0000115>Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>catalytic activity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0003939 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0003939">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0003824"/>
<obo:IAO_0000111>L-iditol 2-dehydrogenase (NAD+) activity</obo:IAO_0000111>
<obo:IAO_0000115>Catalysis of the reaction: L-iditol + NAD+ = L-sorbose + NADH + H+. Acts on a number of sugar alcohols, including (but not limited to) L-iditol, D-glucitol, D-xylitol, and D-galactitol.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>L-iditol 2-dehydrogenase (NAD+) activity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0003964 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0003964">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0003824"/>
<obo:IAO_0000111>RNA-directed DNA polymerase activity</obo:IAO_0000111>
<obo:IAO_0000115>Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1); RNA-template-directed extension of the 3'-end of a DNA strand by one deoxynucleotide at a time.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>RNA-directed DNA polymerase activity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0003990 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0003990">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0003824"/>
<obo:IAO_0000111>acetylcholinesterase activity</obo:IAO_0000111>
<obo:IAO_0000115>Catalysis of the reaction: acetylcholine + H2O = choline + acetate.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>acetylcholinesterase activity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0003997 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0003997">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0003824"/>
<obo:IAO_0000111>acyl-CoA oxidase activity</obo:IAO_0000111>
<obo:IAO_0000115>Catalysis of the reaction: a 2,3-saturated acyl-CoA + O2 = a (2E)-enoyl-CoA + H2O2.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>acyl-CoA oxidase activity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0004021 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0004021">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0003824"/>
<obo:IAO_0000111>L-alanine:2-oxoglutarate aminotransferase activity</obo:IAO_0000111>
<obo:IAO_0000115>Catalysis of the reaction: 2-oxoglutarate + L-alanine = L-glutamate + pyruvate.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>L-alanine:2-oxoglutarate aminotransferase activity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0004035 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0004035">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0003824"/>
<obo:IAO_0000111>alkaline phosphatase activity</obo:IAO_0000111>
<obo:IAO_0000115>Catalysis of the reaction: a phosphate monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>alkaline phosphatase activity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0004069 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0004069">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0003824"/>
<obo:IAO_0000111>L-aspartate:2-oxoglutarate aminotransferase activity</obo:IAO_0000111>
<obo:IAO_0000115>Catalysis of the reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>L-aspartate:2-oxoglutarate aminotransferase activity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0004104 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0004104">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0003824"/>
<obo:IAO_0000111>cholinesterase activity</obo:IAO_0000111>
<obo:IAO_0000115>Catalysis of the reaction: an acylcholine + H2O = choline + a carboxylic acid anion.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>cholinesterase activity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0004111 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0004111">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0003824"/>
<obo:IAO_0000111>creatine kinase activity</obo:IAO_0000111>
<obo:IAO_0000115>Catalysis of the reaction: ATP + creatine = N-phosphocreatine + ADP + 2 H+.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>creatine kinase activity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0004353 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0004353">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0003824"/>
<obo:IAO_0000111>glutamate dehydrogenase [NAD(P)+] activity</obo:IAO_0000111>
<obo:IAO_0000115>Catalysis of the reaction: L-glutamate + H2O + NAD(P)+ = 2-oxoglutarate + NH3 + NAD(P)H + H+.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>glutamate dehydrogenase [NAD(P)+] activity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0004364 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0004364">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0003824"/>
<obo:IAO_0000111>glutathione transferase activity</obo:IAO_0000111>
<obo:IAO_0000115>Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>glutathione transferase activity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0004448 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0004448">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0003824"/>
<obo:IAO_0000111>isocitrate dehydrogenase [NAD(P)+] activity</obo:IAO_0000111>
<obo:IAO_0000115>Catalysis of the reaction: isocitrate + NAD(P)+ = 2-oxoglutarate + CO2 + NAD(P)H.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>isocitrate dehydrogenase [NAD(P)+] activity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0004457 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0004457">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0003824"/>
<obo:IAO_0000111>lactate dehydrogenase activity</obo:IAO_0000111>
<obo:IAO_0000115>Catalysis of the reaction: lactate + NAD+ = H+ + NADH + pyruvate.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>lactate dehydrogenase activity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0004540 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0004540">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0003824"/>
<obo:IAO_0000111>RNA nuclease activity</obo:IAO_0000111>
<obo:IAO_0000115>Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>RNA nuclease activity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0005216 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0005216">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0009987"/>
<obo:IAO_0000111>monoatomic ion channel activity</obo:IAO_0000111>
<obo:IAO_0000115>Enables the facilitated diffusion of a monoatomic ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. May be either selective (it enables passage of a specific ion only) or non-selective (it enables passage of two or more ions of same charge but different size).</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>monoatomic ion channel activity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0005575 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0005575">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000111>cellular_component</obo:IAO_0000111>
<obo:IAO_0000115>A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>cellular_component</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0005577 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0005577">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0032991"/>
<obo:IAO_0000111>fibrinogen complex</obo:IAO_0000111>
<obo:IAO_0000115>A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>fibrinogen complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0005694 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0005694">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0005575"/>
<obo:IAO_0000111>chromosome</obo:IAO_0000111>
<obo:IAO_0000115>A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>chromosome</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0005739 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0005739">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0043227"/>
<obo:IAO_0000111>mitochondrion</obo:IAO_0000111>
<obo:IAO_0000115>A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>mitochondrion</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0006006 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0006006">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>glucose metabolic process</obo:IAO_0000111>
<obo:IAO_0000115>The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>glucose metabolic process</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0006260 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0006260">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>DNA replication</obo:IAO_0000111>
<obo:IAO_0000115>The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by the origin recognition complex, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>DNA replication</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0006338 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0006338">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0009987"/>
<obo:IAO_0000111>chromatin remodeling</obo:IAO_0000111>
<obo:IAO_0000115>A dynamic process of chromatin reorganization resulting in changes to chromatin structure. These changes allow DNA metabolic processes such as transcriptional regulation, DNA recombination, DNA repair, and DNA replication.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>chromatin remodeling</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0006909 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0006909">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>phagocytosis</obo:IAO_0000111>
<obo:IAO_0000115>A vesicle-mediated transport process that results in the engulfment of external particulate material by phagocytes and their delivery to the lysosome. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>phagocytosis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0006955 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0006955">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0050896"/>
<obo:IAO_0000111>immune response</obo:IAO_0000111>
<obo:IAO_0000115>Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>immune response</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0006974 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0006974">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0050896"/>
<obo:IAO_0000111>DNA damage response</obo:IAO_0000111>
<obo:IAO_0000115>Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>DNA damage response</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0007049 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0007049">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>cell cycle</obo:IAO_0000111>
<obo:IAO_0000115>The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>cell cycle</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0007596 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0007596">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>blood coagulation</obo:IAO_0000111>
<obo:IAO_0000115>The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>blood coagulation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0008150 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0008150">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
<owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<obo:IAO_0000111>biological_process</obo:IAO_0000111>
<obo:IAO_0000115>A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>biological_process</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0008228 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0008228">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0006909"/>
<obo:IAO_0000111>opsonization</obo:IAO_0000111>
<obo:IAO_0000115>The process in which a microorganism (or other particulate material) is rendered more susceptible to phagocytosis by coating with an opsonin, a blood serum protein such as a complement component or antibody.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>opsonization</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0008253 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0008253">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0003824"/>
<obo:IAO_0000111>5'-nucleotidase activity</obo:IAO_0000111>
<obo:IAO_0000115>Catalysis of the reaction: a 5'-ribonucleotide + H2O = a ribonucleoside + phosphate.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>5'-nucleotidase activity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0008283 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0008283">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>cell population proliferation</obo:IAO_0000111>
<obo:IAO_0000115>The multiplication or reproduction of cells, resulting in the expansion of a cell population.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>cell population proliferation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0009566 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0009566">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>fertilization</obo:IAO_0000111>
<obo:IAO_0000115>The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>fertilization</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0009987 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0009987">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>cellular process</obo:IAO_0000111>
<obo:IAO_0000115>Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>cellular process</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0010467 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0010467">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>gene expression</obo:IAO_0000111>
<obo:IAO_0000115>The process in which a gene's sequence is converted into a mature gene product (protein or RNA). This includes the production of an RNA transcript and its processing, as well as translation and maturation for protein-coding genes.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>gene expression</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0010573 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0010573">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>vascular endothelial growth factor production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of vascular endothelial growth factor production due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>vascular endothelial growth factor production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0015925 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0015925">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0003824"/>
<obo:IAO_0000111>galactosidase activity</obo:IAO_0000111>
<obo:IAO_0000115>Catalysis of the hydrolysis of galactosyl compounds, substances containing a group derived from a cyclic form of galactose or a galactose derivative.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>galactosidase activity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0016064 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0016064">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>immunoglobulin mediated immune response</obo:IAO_0000111>
<obo:IAO_0000115>An immune response mediated by immunoglobulins, whether cell-bound or in solution.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>immunoglobulin mediated immune response</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0016160 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0016160">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0003824"/>
<obo:IAO_0000111>amylase activity</obo:IAO_0000111>
<obo:IAO_0000115>Catalysis of the hydrolysis of amylose or an amylose derivative.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>amylase activity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0016231 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0016231">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0003824"/>
<obo:IAO_0000111>beta-N-acetylglucosaminidase activity</obo:IAO_0000111>
<obo:IAO_0000115>Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-beta-D-glucosaminides.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>beta-N-acetylglucosaminidase activity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0016788 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0016788">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0003824"/>
<obo:IAO_0000111>hydrolase activity, acting on ester bonds</obo:IAO_0000111>
<obo:IAO_0000115>Catalysis of the hydrolysis of any ester bond.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>hydrolase activity, acting on ester bonds</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0019814 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0019814">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0032991"/>
<obo:IAO_0000111>immunoglobulin complex</obo:IAO_0000111>
<obo:IAO_0000115>A protein complex that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains, held together by disulfide bonds and sometimes complexed with additional proteins. An immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>immunoglobulin complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0019815 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0019815">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110022"/>
<obo:IAO_0000111>B cell receptor complex</obo:IAO_0000111>
<obo:IAO_0000115>An immunoglobulin complex that is present in the plasma membrane of B cells and that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>B cell receptor complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0019882 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0019882">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>antigen processing and presentation</obo:IAO_0000111>
<obo:IAO_0000115>The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>antigen processing and presentation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0019904 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0019904">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001588"/>
<obo:IAO_0000111>protein domain specific binding</obo:IAO_0000111>
<obo:IAO_0000115>Binding to a specific domain of a protein.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>protein domain specific binding</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0030041 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0030041">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>actin filament polymerization</obo:IAO_0000111>
<obo:IAO_0000115>Assembly of actin filaments by the addition of actin monomers to a filament.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>actin filament polymerization</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0030097 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0030097">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>hemopoiesis</obo:IAO_0000111>
<obo:IAO_0000115>The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>hemopoiesis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032601 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032601">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>connective tissue growth factor production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of connective tissue growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>connective tissue growth factor production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032602 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032602">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>chemokine production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>chemokine production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032604 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032604">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>granulocyte macrophage colony-stimulating factor production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of granulocyte macrophage colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>granulocyte macrophage colony-stimulating factor production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032605 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032605">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>hepatocyte growth factor production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of hepatocyte growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>hepatocyte growth factor production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032606 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032606">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>type I interferon production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of type I interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>type I interferon production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032607 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032607">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0032606"/>
<obo:IAO_0000111>interferon-alpha production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of interferon-alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>interferon-alpha production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032608 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032608">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>interferon-beta production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of interferon-beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>interferon-beta production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032609 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032609">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>type II interferon production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of interferon-gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon-gamma is also known as type II interferon.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>type II interferon production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032610 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032610">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0032612"/>
<obo:IAO_0000111>interleukin-1 alpha production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of interleukin-1 alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>interleukin-1 alpha production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032611 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032611">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0032612"/>
<obo:IAO_0000111>interleukin-1 beta production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of interleukin-1 beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>interleukin-1 beta production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032612 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032612">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>interleukin-1 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of interleukin-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>interleukin-1 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032613 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032613">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>interleukin-10 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of interleukin-10 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>interleukin-10 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032614 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032614">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>interleukin-11 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of interleukin-11 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>interleukin-11 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032615 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032615">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>interleukin-12 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of interleukin-12 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>interleukin-12 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032616 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032616">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>interleukin-13 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of interleukin-13 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>interleukin-13 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032617 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032617">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>obsolete interleukin-14 production</obo:IAO_0000111>
<obo:IAO_0000115>OBSOLETE. The appearance of interleukin-14 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>obsolete interleukin-14 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032618 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032618">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>interleukin-15 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of interleukin-15 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>interleukin-15 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032619 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032619">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>interleukin-16 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of interleukin-16 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>interleukin-16 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032620 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032620">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>interleukin-17 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of any member of the interleukin-17 family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>interleukin-17 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032621 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032621">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>interleukin-18 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of interleukin-18 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>interleukin-18 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032622 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032622">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>interleukin-19 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of interleukin-19 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>interleukin-19 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032623 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032623">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>interleukin-2 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of interleukin-2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>interleukin-2 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032624 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032624">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>interleukin-20 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of interleukin-20 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>interleukin-20 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032625 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032625">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>interleukin-21 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of interleukin-21 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>interleukin-21 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032626 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032626">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>interleukin-22 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of interleukin-22 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>interleukin-22 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032627 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032627">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>interleukin-23 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of interleukin-23 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>interleukin-23 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032628 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032628">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>interleukin-24 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of interleukin-24 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>interleukin-24 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032629 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032629">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>interleukin-25 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of interleukin-25 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>interleukin-25 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032630 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032630">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>interleukin-26 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of interleukin-26 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>interleukin-26 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032631 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032631">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>interleukin-27 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of interleukin-27 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>interleukin-27 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032632 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032632">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>interleukin-3 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of interleukin-3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>interleukin-3 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032633 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032633">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>interleukin-4 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of interleukin-4 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>interleukin-4 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032634 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032634">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>interleukin-5 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of interleukin-5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>interleukin-5 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032635 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032635">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>interleukin-6 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of interleukin-6 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>interleukin-6 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032636 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032636">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>interleukin-7 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of interleukin-7 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>interleukin-7 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032637 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032637">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>interleukin-8 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of interleukin-8 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>interleukin-8 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032638 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032638">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>interleukin-9 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of interleukin-9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>interleukin-9 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032639 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032639">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>TRAIL production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of TRAIL due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>TRAIL production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032640 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032640">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0071706"/>
<obo:IAO_0000111>tumor necrosis factor production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of tumor necrosis factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Tumor necrosis factor is an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis.</obo:IAO_0000115>
<obo:IAO_0000118>TNF alpha production</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>tumor necrosis factor production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032641 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032641">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0071706"/>
<obo:IAO_0000111>lymphotoxin A production</obo:IAO_0000111>
<obo:IAO_0000115>The chemical reactions and pathways resulting in the formation of the cytokine lymphotoxin A.</obo:IAO_0000115>
<obo:IAO_0000118>TNF beta production</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>lymphotoxin A production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032905 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032905">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>transforming growth factor beta1 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of transforming growth factor-beta1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>transforming growth factor beta1 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032906 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032906">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>transforming growth factor beta2 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of transforming growth factor-beta2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>transforming growth factor beta2 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032907 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032907">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>transforming growth factor beta3 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of transforming growth factor-beta3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>transforming growth factor beta3 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0032991 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032991">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>protein-containing complex</obo:IAO_0000111>
<obo:IAO_0000112>A ribosome is a protein complex.</obo:IAO_0000112>
<obo:IAO_0000115>A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.</obo:IAO_0000115>
<obo:IAO_0000118>protein complex</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>protein-containing complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0033036 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0033036">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>macromolecule localization</obo:IAO_0000111>
<obo:IAO_0000115>Any process in which a macromolecule is transported to, or maintained in, a specific location.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>macromolecule localization</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0034061 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0034061">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0003824"/>
<obo:IAO_0000111>DNA polymerase activity</obo:IAO_0000111>
<obo:IAO_0000115>Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>DNA polymerase activity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0034343 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0034343">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>type III interferon production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of type III interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon lambda is the only member of the type III interferon found so far.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>type III interferon production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0035393 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0035393">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0032602"/>
<obo:IAO_0000111>chemokine (C-X-C motif) ligand 9 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of chemokine (C-X-C motif) ligand 9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>chemokine (C-X-C motif) ligand 9 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0035397 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0035397">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0002250"/>
<obo:IAO_0000111>helper T cell enhancement of adaptive immune response</obo:IAO_0000111>
<obo:IAO_0000115>Positive regulation of an adaptive immune response mediated via cytokine production by helper T cell.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>helper T cell enhancement of adaptive immune response</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0035398 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0035398">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0035397"/>
<obo:IAO_0000111>helper T cell enhancement of T cell mediated immune response</obo:IAO_0000111>
<obo:IAO_0000115>Positive regulation of a T cell mediated immune response mediated via cytokine production by a helper T cell.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>helper T cell enhancement of T cell mediated immune response</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0035399 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0035399">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0035397"/>
<obo:IAO_0000111>helper T cell enhancement of B cell mediated immune response</obo:IAO_0000111>
<obo:IAO_0000115>Positive regulation of a B cell mediated immune response mediated via cytokine production by a helper T cell.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>helper T cell enhancement of B cell mediated immune response</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0035746 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0035746">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>granzyme A production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of granzyme A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>granzyme A production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0035944 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0035944">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>perforin production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of a perforin protein due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>perforin production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0036262 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0036262">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>granulysin production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of granulysin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>granulysin production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0036392 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0036392">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0032602"/>
<obo:IAO_0000111>chemokine (C-C motif) ligand 20 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of chemokine (C-C motif) ligand 20 (CCL20) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>chemokine (C-C motif) ligand 20 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0042098 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0042098">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008283"/>
<obo:IAO_0000111>T cell proliferation</obo:IAO_0000111>
<obo:IAO_0000115>The expansion of a T cell population by cell division. Follows T cell activation.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>T cell proliferation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0042101 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0042101">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110022"/>
<obo:IAO_0000111>T cell receptor complex</obo:IAO_0000111>
<obo:IAO_0000115>A protein complex that contains a disulfide-linked heterodimer of T cell receptor (TCR) chains, which are members of the immunoglobulin superfamily, and mediates antigen recognition, ultimately resulting in T cell activation. The TCR heterodimer is associated with the CD3 complex, which consists of the nonpolymorphic polypeptides gamma, delta, epsilon, zeta, and, in some cases, eta (an RNA splice variant of zeta) or Fc epsilon chains.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>T cell receptor complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0042110 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0042110">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>T cell activation</obo:IAO_0000111>
<obo:IAO_0000115>The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>T cell activation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0042571 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0042571">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0019814"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110022"/>
<obo:IAO_0000111>immunoglobulin complex, circulating</obo:IAO_0000111>
<obo:IAO_0000115>An immunoglobulin complex that is secreted into extracellular space and found in mucosal areas or other tissues or circulating in the blood or lymph. In its canonical form, a circulating immunoglobulin complex is composed of two identical heavy chains and two identical light chains, held together by disulfide bonds. Some forms of are polymers of the basic structure and contain additional components such as J-chain and the secretory component.</obo:IAO_0000115>
<obo:IAO_0000118>antibody</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<obo:OBI_9991118>antibody</obo:OBI_9991118>
<rdfs:label>immunoglobulin complex, circulating</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0042575 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0042575">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0032991"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000427"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0034061"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>DNA polymerase complex</obo:IAO_0000111>
<obo:IAO_0000115>A protein complex that possesses DNA polymerase activity and is involved in template directed synthesis of DNA.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>DNA polymerase complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0042605 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0042605">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0003823"/>
<obo:IAO_0000111>peptide antigen binding</obo:IAO_0000111>
<obo:IAO_0000115>Binding to an antigen peptide.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>peptide antigen binding</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0042611 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0042611">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0032991"/>
<obo:IAO_0000111>MHC protein complex</obo:IAO_0000111>
<obo:IAO_0000115>A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/mro.owl"/>
<rdfs:label>MHC protein complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0043227 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0043227">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0005575"/>
<obo:IAO_0000111>membrane-bounded organelle</obo:IAO_0000111>
<obo:IAO_0000115>Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>membrane-bounded organelle</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0043316 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0043316">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001906"/>
<obo:IAO_0000111>cytotoxic T cell degranulation</obo:IAO_0000111>
<obo:IAO_0000115>The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a cytotoxic T cell.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>cytotoxic T cell degranulation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0043565 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0043565">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001588"/>
<obo:IAO_0000111>sequence-specific DNA binding</obo:IAO_0000111>
<obo:IAO_0000115>Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>sequence-specific DNA binding</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0044807 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0044807">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>macrophage migration inhibitory factor production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of macrophage migration inhibitory factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>macrophage migration inhibitory factor production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0044808 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0044808">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>oncostatin M production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of oncostatin M due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>oncostatin M production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0044809 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0044809">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0032602"/>
<obo:IAO_0000111>chemokine (C-C motif) ligand 17 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of chemokine (C-C motif) ligand 17 (CCL17) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>chemokine (C-C motif) ligand 17 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0047823 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0047823">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0003824"/>
<obo:IAO_0000111>D-glutamyltransferase activity</obo:IAO_0000111>
<obo:IAO_0000115>Catalysis of the reaction: D-glutamate + D-glutamine = gamma-D-glutamyl-D-glutamate + NH4+. Can also transfer additional glutamyl residues to a peptide, extending the polypeptide chain.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>D-glutamyltransferase activity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0048869 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0048869">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>cellular developmental process</obo:IAO_0000111>
<obo:IAO_0000115>A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>cellular developmental process</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0050896 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0050896">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>response to stimulus</obo:IAO_0000111>
<obo:IAO_0000115>Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>response to stimulus</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0051276 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0051276">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>chromosome organization</obo:IAO_0000111>
<obo:IAO_0000115>A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>chromosome organization</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0052689 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0052689">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0003824"/>
<obo:IAO_0000111>carboxylic ester hydrolase activity</obo:IAO_0000111>
<obo:IAO_0000115>Catalysis of the hydrolysis of a carboxylic ester bond.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>carboxylic ester hydrolase activity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0070288 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0070288">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0032991"/>
<obo:IAO_0000111>ferritin complex</obo:IAO_0000111>
<obo:IAO_0000115>A protein complex that binds iron and acts as a major iron storage system. There are three major subclasses of ferritins: the classical ferritins (Ftn), the heme-containing bacterioferritins (Bfr) and the DNA-binding proteins from starved cells (Dps). Ftn and Bfr are made of 24 subunits, whereas Dps are smaller with 12 subunits. Ftn is found in most kindoms, while Bfr and Dps are restricted to prokaryotes.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>ferritin complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0070358 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0070358">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>actin polymerization-dependent cell motility</obo:IAO_0000111>
<obo:IAO_0000115>A process involved in the controlled movement of a bacterial cell powered by the continuous polymerization of actin at one pole of the cell.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>actin polymerization-dependent cell motility</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0071604 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0071604">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>transforming growth factor beta production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of any member of the transforming growth factor-beta family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Transforming growth factor-beta family members include TGF-B1, TGF-B2, and TGF-B3.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>transforming growth factor beta production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0071605 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0071605">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0032602"/>
<obo:IAO_0000111>monocyte chemotactic protein-1 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of monocyte chemotactic protein-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>monocyte chemotactic protein-1 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0071606 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0071606">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0032602"/>
<obo:IAO_0000111>chemokine (C-C motif) ligand 4 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of chemokine (C-C motif) ligand 4 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>chemokine (C-C motif) ligand 4 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0071607 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0071607">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0032602"/>
<obo:IAO_0000111>macrophage inflammatory protein-1 gamma production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of macrophage inflammatory protein-1 gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>macrophage inflammatory protein-1 gamma production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0071608 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0071608">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0032602"/>
<obo:IAO_0000111>macrophage inflammatory protein-1 alpha production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of macrophage inflammatory protein 1 alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>macrophage inflammatory protein-1 alpha production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0071609 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0071609">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0032602"/>
<obo:IAO_0000111>chemokine (C-C motif) ligand 5 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of chemokine (C-C motif) ligand 5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>chemokine (C-C motif) ligand 5 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0071610 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0071610">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0032602"/>
<obo:IAO_0000111>chemokine (C-C motif) ligand 1 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of chemokine (C-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>chemokine (C-C motif) ligand 1 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0071611 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0071611">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>granulocyte colony-stimulating factor production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of granulocyte colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>granulocyte colony-stimulating factor production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0071612 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0071612">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0032602"/>
<obo:IAO_0000111>IP-10 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of IP-10 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>IP-10 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0071613 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0071613">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>granzyme B production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of granzyme B due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>granzyme B production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0071706 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0071706">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>tumor necrosis factor superfamily cytokine production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of any member of the TNF superfamily due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>tumor necrosis factor superfamily cytokine production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0071735 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0071735">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0019814"/>
<obo:IAO_0000111>IgG immunoglobulin complex</obo:IAO_0000111>
<obo:IAO_0000115>A protein complex composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgG immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>IgG immunoglobulin complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0071742 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0071742">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0019814"/>
<obo:IAO_0000111>IgE immunoglobulin complex</obo:IAO_0000111>
<obo:IAO_0000115>A protein complex composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgE immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>IgE immunoglobulin complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0071745 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0071745">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0019814"/>
<obo:IAO_0000111>IgA immunoglobulin complex</obo:IAO_0000111>
<obo:IAO_0000115>A protein complex composed of two identical immunoglobulin heavy chains of the IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and sometimes complexed with J chain or J chain and secretory component. An IgA immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>IgA immunoglobulin complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0071753 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0071753">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0019814"/>
<obo:IAO_0000111>IgM immunoglobulin complex</obo:IAO_0000111>
<obo:IAO_0000115>A protein complex composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and in its circulating form complexed with J chain in polymeric forms. An IgM immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>IgM immunoglobulin complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0071924 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0071924">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0032602"/>
<obo:IAO_0000111>chemokine (C-C motif) ligand 22 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of chemokine (C-C motif) ligand 22 (CCL22) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>chemokine (C-C motif) ligand 22 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0072535 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0072535">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0071706"/>
<obo:IAO_0000111>tumor necrosis factor (ligand) superfamily member 11 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of tumor necrosis factor superfamily member 11 (TNFSF11; RANKL) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>tumor necrosis factor (ligand) superfamily member 11 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0097087 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0097087">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0032620"/>
<obo:IAO_0000111>interleukin-17A production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of interleukin-17A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>interleukin-17A production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0097088 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0097088">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0032620"/>
<obo:IAO_0000111>interleukin-17F production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of interleukin-17F due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>interleukin-17F production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0097278 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0097278">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001906"/>
<obo:IAO_0000111>complement-dependent cytotoxicity</obo:IAO_0000111>
<obo:IAO_0000115>Cell killing caused by the membrane attack complex formed following complement activation.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>complement-dependent cytotoxicity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0097280 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0097280">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0006955"/>
<obo:IAO_0000111>histamine secretion mediated by immunoglobulin</obo:IAO_0000111>
<obo:IAO_0000115>Histamine release triggered by the binding of an antigen to an immunoglobulin bound to the cell surface.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>histamine secretion mediated by immunoglobulin</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0097281 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0097281">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0016064"/>
<obo:IAO_0000111>immune complex formation</obo:IAO_0000111>
<obo:IAO_0000115>The process that gives rise to an immune complex. Immune complexes are clusters of antibodies bound to antigen, to which complement may also be fixed, and which may precipitate or remain in solution. Examples are the clumping of cells such as bacteria or red blood cells in the presence of an antibody, precipitation of a toxin after an antibody binds to it, and clumping of viral particles as a result of antibody binding to the virus.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>immune complex formation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0097282 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0097282">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0016064"/>
<obo:IAO_0000111>immunoglobulin-mediated neutralization</obo:IAO_0000111>
<obo:IAO_0000115>The inhibition of an antigen's biological effects by antibody binding to it. An example is neutralization of diphtheria toxin by preventing its entry into human cells via the binding of antibody specific for diphtheria toxin.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>immunoglobulin-mediated neutralization</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0097388 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0097388">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0032602"/>
<obo:IAO_0000111>chemokine (C-C motif) ligand 19 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of chemokine (C-C motif) ligand 19 (CCL19) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>chemokine (C-C motif) ligand 19 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0097389 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0097389">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0032602"/>
<obo:IAO_0000111>chemokine (C-C motif) ligand 21 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of chemokine (C-C motif) ligand 21 (CCL21) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>chemokine (C-C motif) ligand 21 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0097390 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0097390">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0032602"/>
<obo:IAO_0000111>chemokine (C-X-C motif) ligand 12 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of chemokine (C-X-C motif) ligand 12 (CXCL12) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>chemokine (C-X-C motif) ligand 12 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0097391 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0097391">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0032602"/>
<obo:IAO_0000111>chemokine (C-X-C motif) ligand 13 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of chemokine (C-X-C motif) ligand 13 (CXCL13) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>chemokine (C-X-C motif) ligand 13 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0097392 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0097392">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0032602"/>
<obo:IAO_0000111>chemokine (C-X-C motif) ligand 16 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of chemokine (C-X-C motif) ligand 16 (CXCL16) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>chemokine (C-X-C motif) ligand 16 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0140730 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0140730">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>amphiregulin production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of amphiregulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Amphiregulin (AREG) is a ligand of the epidermal growth factor receptor (EGFR), a widely expressed transmembrane tyrosine kinase. AREG is synthesized as a membrane-anchored precursor protein that can engage in juxtacrine signaling on adjacent cells. Alternatively, after proteolytic processing by cell membrane proteases, mainly TACE/ADAM17, AREG is secreted and behaves as an autocrine or paracrine factor.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>amphiregulin production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0140779 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0140779">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>XCL1 production</obo:IAO_0000111>
<obo:IAO_0000115>The appearance of XCL1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
<rdfs:label>XCL1 production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000855 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000855">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000016"/>
<obo:IAO_0000111>Insulin resistance</obo:IAO_0000111>
<obo:IAO_0000115>Increased resistance towards insulin, that is, diminished effectiveness of insulin in reducing blood glucose levels.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/hp.owl"/>
<rdfs:label>Insulin resistance</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002664 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002664">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>Neoplasm</obo:IAO_0000111>
<obo:IAO_0000115>An organ or organ-system abnormality that consists of uncontrolled autonomous cell-proliferation which can occur in any part of the body as a benign or malignant neoplasm (tumor).</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/hp.owl"/>
<rdfs:label>Neoplasm</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000001 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000001">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
<obo:IAO_0000111 xml:lang="en">conditional specification</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A directive information entity that specifies what should happen if the trigger condition is fulfilled.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">conditional specification</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000003 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000003">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000009"/>
<obo:IAO_0000111 xml:lang="en">measurement unit label</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A measurement unit label is as a label that is part of a scalar measurement datum and denotes a unit of measure.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">measurement unit label</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000005 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000005">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
<obo:IAO_0000111 xml:lang="en">objective specification</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A directive information entity that describes an intended process endpoint. When part of a plan specification the concretization is realized in a planned process in which the bearer tries to effect the world so that the process endpoint is achieved.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">objective specification</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000006 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000006">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
<obo:IAO_0000111 xml:lang="en">narrative object</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A narrative object is an information content entity that is a set of propositions.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">narrative object</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000009 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000009">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
<obo:IAO_0000111 xml:lang="en">datum label</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A label is a symbol that is part of some other datum and is used to either partially define the denotation of that datum or to provide a means for identifying the datum as a member of the set of data with the same label</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">datum label</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000010 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000010">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000104"/>
<obo:IAO_0000111 xml:lang="en">software</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">Software is a plan specification composed of a series of instructions that can be
interpreted by or directly executed by a processing unit.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">software</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000027 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000027">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
<obo:IAO_0000111 xml:lang="en">data item</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">An information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ogms.owl"/>
<rdfs:label xml:lang="en">data item</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000028 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000028">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
<obo:IAO_0000111 xml:lang="en">symbol</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">An information content entity that is a mark(s) or character(s) used as a conventional representation of another entity.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">symbol</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000030 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000030">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000031"/>
<obo:IAO_0000111 xml:lang="en">information content entity</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A generically dependent continuant that is about some thing.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ogms.owl"/>
<rdfs:label xml:lang="en">information content entity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000032 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000032">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0001938"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001931"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">scalar measurement datum</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A scalar measurement datum is a measurement datum that is composed of two parts, numerals and a unit label.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">scalar measurement datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000033 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000033">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
<obo:IAO_0000111 xml:lang="en">directive information entity</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">An information content entity whose concretizations indicate to their bearer how to realize them in a process.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">directive information entity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000037 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000037">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000038"/>
<obo:IAO_0000111 xml:lang="en">dot plot</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A dot plot is a report graph which is a graphical representation of data where each data point is represented by a single dot placed on coordinates corresponding to data point values in particular dimensions.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">dot plot</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000038 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000038">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000308"/>
<obo:IAO_0000111 xml:lang="en">graph</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A diagram that presents one or more tuples of information by mapping those tuples in to a two dimensional space in a non arbitrary way.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">graph</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000055 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000055">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000001"/>
<obo:IAO_0000111 xml:lang="en">rule</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A rule is an executable which guides, defines, restricts actions.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">rule</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000064 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000064">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000104"/>
<obo:IAO_0000111 xml:lang="en">algorithm</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A plan specification which describes the inputs and output of mathematical functions as well as workflow of execution for achieving an predefined objective. Algorithms are realized usually by means of implementation as computer programs for execution by automata.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">algorithm</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000078 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000078">
<owl:equivalentClass>
<owl:Class>
<owl:oneOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000002"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000120"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000121"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000122"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000123"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000124"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000125"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000423"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000428"/>
</owl:oneOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000102"/>
<obo:IAO_0000111 xml:lang="en">curation status specification</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">Better to represent curation as a process with parts and then relate labels to that process (in IAO meeting)</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">PERSON:Bill Bug</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">GROUP:OBI:<http://purl.obolibrary.org/obo/obi></obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">OBI_0000266</obo:IAO_0000119>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">curation status specification</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000079 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000079">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000038"/>
<obo:IAO_0000111 xml:lang="en">density plot</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A density plot is a report graph which is a graphical representation of data where the tint of a particular pixel corresponds to some kind of function corresponding the the amount of data points relativelly with their distance from the the pixel.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">density plot</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000088 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000088">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000310"/>
<obo:IAO_0000111 xml:lang="en">report</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A document assembled by an author for the purpose of providing information for the audience. A report is the output of a documenting process and has the objective to be consumed by a specific audience. Topic of the report is on something that has completed. A report is not a single figure. Examples of reports are journal article, patent application, grant progress report, case report (not patient record).</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">report</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000098 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000098">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
<obo:IAO_0000111 xml:lang="en">data format specification</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A data format specification is the information content borne by the document published defining the specification.
Example: The ISO document specifying what encompasses an XML document; The instructions in a XSD file</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">data format specification</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000100 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000100">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
<obo:IAO_0000111 xml:lang="en">data set</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A data item that is an aggregate of other data items of the same type that have something in common. Averages and distributions can be determined for data sets.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">data set</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000101 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000101">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000308"/>
<obo:IAO_0000111 xml:lang="en">image</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">An image is an affine projection to a two dimensional surface, of measurements of some quality of an entity or entities repeated at regular intervals across a spatial range, where the measurements are represented as color and luminosity on the projected on surface.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">image</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000102 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000102">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
<obo:IAO_0000111 xml:lang="en">data about an ontology part</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">Data about an ontology part is a data item about a part of an ontology, for example a term</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000117>
<rdfs:label xml:lang="en">data about an ontology part</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000104 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000104">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
<obo:IAO_0000111 xml:lang="en">plan specification</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A directive information entity with action specifications and objective specifications as parts, and that may be concretized as a realizable entity that, if realized, is realized in a process in which the bearer tries to achieve the objectives by taking the actions specified.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">plan specification</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000109 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000109">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0001938"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001933"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">measurement datum</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A measurement datum is an information content entity that is a recording of the output of a measurement such as produced by a device.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">measurement datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000144 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000144">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000300"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001909"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000124"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000338"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">conclusion textual entity</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A textual entity that expresses the results of reasoning about a problem, for instance as typically found towards the end of scientific papers.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">conclusion textual entity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000178 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000178">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000111 xml:lang="en">material information bearer</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A material entity in which a concretization of an information content entity inheres.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">material information bearer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000179 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000179">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000038"/>
<obo:IAO_0000111 xml:lang="en">histogram</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A histogram is a report graph which is a statistical description of a
distribution in terms of occurrence frequencies of different event classes.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">histogram</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000180 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000180">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000038"/>
<obo:IAO_0000111 xml:lang="en">heatmap</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A heatmap is a report graph which is a graphical representation of data
where the values taken by a variable(s) are shown as colors in a
two-dimensional map.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">heatmap</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000183 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000183">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000038"/>
<obo:IAO_0000111 xml:lang="en">dendrogram</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A dendrogram is a report graph which is a tree diagram
frequently used to illustrate the arrangement of the clusters produced by a
clustering algorithm.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">dendrogram</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000184 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000184">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000038"/>
<obo:IAO_0000111 xml:lang="en">scatter plot</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A scatterplot is a graph which uses Cartesian coordinates to display values for two variables for a set of data. The data is displayed as a collection of points, each having the value of one variable determining the position on the horizontal axis and the value of the other variable determining the position on the vertical axis.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">scatter plot</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000225 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000225">
<owl:equivalentClass>
<owl:Class>
<owl:oneOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000226"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000227"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000228"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000229"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OMO_0001000"/>
</owl:oneOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000102"/>
<obo:IAO_0000111 xml:lang="en">obsolescence reason specification</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">The creation of this class has been inspired in part by Werner Ceusters' paper, Applying evolutionary terminology auditing to the Gene Ontology.</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">PERSON: Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">PERSON: Melanie Courtot</obo:IAO_0000117>
<rdfs:label xml:lang="en">obsolescence reason specification</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000300 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000300">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
<obo:IAO_0000111 xml:lang="en">textual entity</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A textual entity is a part of a manifestation (FRBR sense), a generically dependent continuant whose concretizations are patterns of glyphs intended to be interpreted as words, formulas, etc.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">textual entity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000306 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000306">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000300"/>
<obo:IAO_0000111 xml:lang="en">table</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A textual entity that contains a two-dimensional arrangement of texts repeated at regular intervals across a spatial range, such that the spatial relationships among the constituent texts expresses propositions</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">table</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000308 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000308">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
<obo:IAO_0000111 xml:lang="en">figure</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">An information content entity consisting of a two dimensional arrangement of information content entities such that the arrangement itself is about something.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">figure</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000310 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000310">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
<obo:IAO_0000111 xml:lang="en">document</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A collection of information content entities intended to be understood together as a whole</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">document</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000311 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000311">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000310"/>
<obo:IAO_0000111 xml:lang="en">publication</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A document that is the output of a publishing process.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">publication</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000312 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000312">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000311"/>
<obo:IAO_0000111 xml:lang="en">publication about an investigation</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A publication that is about an investigation</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">publication about an investigation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000401 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000401">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
<obo:IAO_0000111 xml:lang="en">one dimensional cartesian spatial coordinate datum</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A cartesion spatial coordinate datum that uses one value to specify a position along a one dimensional spatial region</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">one dimensional cartesian spatial coordinate datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000408 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000408">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000032"/>
<obo:IAO_0000111 xml:lang="en">length measurement datum</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A scalar measurement datum that is the result of measurement of length quality</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">length measurement datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000409 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000409">
<owl:equivalentClass>
<owl:Class>
<owl:oneOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000410"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000420"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000421"/>
</owl:oneOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000102"/>
<obo:IAO_0000111 xml:lang="en">denotator type</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">The Basic Formal Ontology ontology makes a distinction between Universals and defined classes, where the formal are "natural kinds" and the latter arbitrary collections of entities.</obo:IAO_0000112>
<obo:IAO_0000115 xml:lang="en">A denotator type indicates how a term should be interpreted from an ontological perspective.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">Barry Smith, Werner Ceusters</obo:IAO_0000119>
<rdfs:label xml:lang="en">denotator type</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000414 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000414">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000032"/>
<obo:IAO_0000111 xml:lang="en">mass measurement datum</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A scalar measurement datum that is the result of measurement of mass quality</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">mass measurement datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000416 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000416">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000032"/>
<obo:IAO_0000111 xml:lang="en">time measurement datum</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A scalar measurement datum that is the result of measuring a temporal interval</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">time measurement datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000422 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000422">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000300"/>
<obo:IAO_0000111 xml:lang="en">postal address</obo:IAO_0000111>
<obo:IAO_0000115>A textual entity that is used as directive to deliver something to a person, or organization</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">postal address</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000429 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000429">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
<obo:IAO_0000111 xml:lang="en">email address</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">email address</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000572 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000572">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<obo:IAO_0000111 xml:lang="en">documenting</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A planned process in which a document is created or added to by including the specified input in it.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">documenting</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000573 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000573">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000038"/>
<obo:IAO_0000111 xml:lang="en">line graph</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A line graph is a type of graph created by connecting a series of data
points together with a line.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">line graph</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000574 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000574">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<obo:IAO_0000111 xml:lang="en">assigning a centrally registered identifier</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A planned process in which a new CRID is created, associated with an entity, and stored in the CRID registry thereby registering it as being associated with some entity</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">assigning a centrally registered identifier</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000577 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000577">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000028"/>
<obo:IAO_0000111 xml:lang="en">centrally registered identifier symbol</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A symbol that is part of a CRID and that is sufficient to look up a record from the CRID's registry.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">centrally registered identifier symbol</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000579 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000579">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
<obo:IAO_0000111 xml:lang="en">centrally registered identifier registry</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A code set of CRID records, each consisting of a CRID symbol and additional information which was recorded in the code set through an assigning a centrally registered identifier process.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">centrally registered identifier registry</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_0000594 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000594">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000010"/>
<obo:IAO_0000111 xml:lang="en">software application</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A software application is software that can be directly executed by some processing unit.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
<rdfs:label xml:lang="en">software application</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_8000000 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000000">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000102"/>
<obo:IAO_0000111 xml:lang="en">ontology module</obo:IAO_0000111>
<obo:IAO_0000116 xml:lang="en">I have placed this under 'data about an ontology part', but this can be discussed. I think this is OK if 'part' is interpreted reflexively, as an ontology module is the whole ontology rather than part of it.</obo:IAO_0000116>
<obo:IAO_0000118 xml:lang="en">ontology file</obo:IAO_0000118>
<obo:IAO_0000232 xml:lang="en">This class and it's subclasses are applied to OWL ontologies. Using an rdf:type triple will result in problems with OWL-DL. I propose that dcterms:type is instead used to connect an ontology URI with a class from this hierarchy. The class hierarchy is not disjoint, so multiple assertions can be made about a single ontology.</obo:IAO_0000232>
<rdfs:label xml:lang="en">ontology module</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_8000001 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000001">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000000"/>
<obo:IAO_0000111 xml:lang="en">base ontology module</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">An ontology module that comprises only of asserted axioms local to the ontology, excludes import directives, and excludes axioms or declarations from external ontologies.</obo:IAO_0000115>
<rdfs:label xml:lang="en">base ontology module</rdfs:label>
<rdfs:seeAlso rdf:resource="https://github.com/INCATools/ontology-starter-kit/issues/50"/>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_8000002 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000002">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000000"/>
<obo:IAO_0000111 xml:lang="en">editors ontology module</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">An ontology module that is intended to be directly edited, typically managed in source control, and typically not intended for direct consumption by end-users.</obo:IAO_0000115>
<obo:IAO_0000118 xml:lang="en">source ontology module</obo:IAO_0000118>
<rdfs:label xml:lang="en">editors ontology module</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_8000003 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000003">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000000"/>
<obo:IAO_0000111 xml:lang="en">main release ontology module</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">An ontology module that is intended to be the primary release product and the one consumed by the majority of tools.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">TODO: Add logical axioms that state that a main release ontology module is derived from (directly or indirectly) an editors module</obo:IAO_0000116>
<rdfs:label xml:lang="en">main release ontology module</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_8000004 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000004">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000000"/>
<obo:IAO_0000111 xml:lang="en">bridge ontology module</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">An ontology module that consists entirely of axioms that connect or bridge two distinct ontology modules. For example, the Uberon-to-ZFA bridge module.</obo:IAO_0000115>
<rdfs:label xml:lang="en">bridge ontology module</rdfs:label>
<rdfs:seeAlso rdf:resource="https://github.com/obophenotype/uberon/wiki/inter-anatomy-ontology-bridge-ontologies"/>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_8000005 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000005">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000006"/>
<obo:IAO_0000111 xml:lang="en">import ontology module</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A subset ontology module that is intended to be imported from another ontology.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">TODO: add axioms that indicate this is the output of a module extraction process.</obo:IAO_0000116>
<obo:IAO_0000118 xml:lang="en">import file</obo:IAO_0000118>
<rdfs:label xml:lang="en">import ontology module</rdfs:label>
<rdfs:seeAlso rdf:resource="http://robot.obolibrary.org/extract"/>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_8000006 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000006">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000000"/>
<obo:IAO_0000111 xml:lang="en">subset ontology module</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">An ontology module that is extracted from a main ontology module and includes only a subset of entities or axioms.</obo:IAO_0000115>
<obo:IAO_0000118 xml:lang="en">ontology slim</obo:IAO_0000118>
<obo:IAO_0000118 xml:lang="en">subset ontology</obo:IAO_0000118>
<rdfs:label xml:lang="en">subset ontology module</rdfs:label>
<rdfs:seeAlso rdf:resource="http://robot.obolibrary.org/filter"/>
<rdfs:seeAlso rdf:resource="http://www.geneontology.org/page/go-slim-and-subset-guide"/>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_8000007 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000007">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000006"/>
<obo:IAO_0000111 xml:lang="en">curation subset ontology module</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A subset ontology that is intended as a whitelist for curators using the ontology. Such a subset will exclude classes that curators should not use for curation.</obo:IAO_0000115>
<rdfs:label xml:lang="en">curation subset ontology module</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_8000008 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000008">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000006"/>
<obo:IAO_0000111 xml:lang="en">analysis ontology module</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">An ontology module that is intended for usage in analysis or discovery applications.</obo:IAO_0000115>
<rdfs:label xml:lang="en">analysis subset ontology module</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_8000009 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000009">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000006"/>
<obo:IAO_0000111 xml:lang="en">single layer ontology module</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A subset ontology that is largely comprised of a single layer or strata in an ontology class hierarchy. The purpose is typically for rolling up for visualization. The classes in the layer need not be disjoint.</obo:IAO_0000115>
<obo:IAO_0000118 xml:lang="en">ribbon subset</obo:IAO_0000118>
<rdfs:label xml:lang="en">single layer subset ontology module</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_8000010 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000010">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000006"/>
<obo:IAO_0000111 xml:lang="en">exclusion subset ontology module</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A subset of an ontology that is intended to be excluded for some purpose. For example, a blacklist of classes.</obo:IAO_0000115>
<obo:IAO_0000118 xml:lang="en">antislim</obo:IAO_0000118>
<rdfs:label xml:lang="en">exclusion subset ontology module</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_8000011 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000011">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000005"/>
<obo:IAO_0000111 xml:lang="en">external import ontology module</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">An imported ontology module that is derived from an external ontology. Derivation methods include the OWLAPI SLME approach.</obo:IAO_0000115>
<obo:IAO_0000118 xml:lang="en">external import</obo:IAO_0000118>
<rdfs:label xml:lang="en">external import ontology module</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_8000012 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000012">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000006"/>
<obo:IAO_0000111 xml:lang="en">species subset ontology module</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A subset ontology that is crafted to either include or exclude a taxonomic grouping of species.</obo:IAO_0000115>
<obo:IAO_0000118 xml:lang="en">taxon subset</obo:IAO_0000118>
<rdfs:label xml:lang="en">species subset ontology module</rdfs:label>
<rdfs:seeAlso rdf:resource="https://github.com/obophenotype/uberon/wiki/Taxon-constraints"/>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_8000013 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000013">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000000"/>
<obo:IAO_0000111 xml:lang="en">reasoned ontology module</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">An ontology module that contains axioms generated by a reasoner. The generated axioms are typically direct SubClassOf axioms, but other possibilities are available.</obo:IAO_0000115>
<rdfs:label xml:lang="en">reasoned ontology module</rdfs:label>
<rdfs:seeAlso rdf:resource="http://robot.obolibrary.org/reason"/>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_8000014 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000014">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000000"/>
<obo:IAO_0000111 xml:lang="en">generated ontology module</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">An ontology module that is automatically generated, for example via a SPARQL query or via template and a CSV.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">TODO: Add axioms (using PROV-O?) that indicate this is the output-of some reasoning process</obo:IAO_0000116>
<rdfs:label xml:lang="en">generated ontology module</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_8000015 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000015">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000014"/>
<obo:IAO_0000111 xml:lang="en">template generated ontology module</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">An ontology module that is automatically generated from a template specification and fillers for slots in that template.</obo:IAO_0000115>
<rdfs:label xml:lang="en">template generated ontology module</rdfs:label>
<rdfs:seeAlso rdf:resource="http://robot.obolibrary.org/template"/>
<rdfs:seeAlso rdf:resource="https://doi.org/10.1186/s13326-017-0126-0"/>
<rdfs:seeAlso rdf:resource="https://github.com/dosumis/dead_simple_owl_design_patterns/"/>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_8000016 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000016">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000004"/>
<obo:IAO_0000111 xml:lang="en">taxonomic bridge ontology module</obo:IAO_0000111>
<rdfs:label xml:lang="en">taxonomic bridge ontology module</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_8000017 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000017">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000006"/>
<obo:IAO_0000111 xml:lang="en">ontology module subsetted by expressivity</obo:IAO_0000111>
<rdfs:label xml:lang="en">ontology module subsetted by expressivity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_8000018 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000018">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000017"/>
<obo:IAO_0000111 xml:lang="en">obo basic subset ontology module</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A subset ontology that is designed for basic applications to continue to make certain simplifying assumptions; many of these simplifying assumptions were based on the initial version of the Gene Ontology, and have become enshrined in many popular and useful tools such as term enrichment tools.
Examples of such assumptions include: traversing the ontology graph ignoring relationship types using a naive algorithm will not lead to cycles (i.e. the ontology is a DAG); every referenced term is declared in the ontology (i.e. there are no dangling clauses).
An ontology is OBO Basic if and only if it has the following characteristics:
DAG
Unidirectional
No Dangling Clauses
Fully Asserted
Fully Labeled
No equivalence axioms
Singly labeled edges
No qualifier lists
No disjointness axioms
No owl-axioms header
No imports</obo:IAO_0000115>
<rdfs:label xml:lang="en">obo basic subset ontology module</rdfs:label>
<rdfs:seeAlso rdf:resource="http://owlcollab.github.io/oboformat/doc/obo-syntax.html#6.2"/>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_8000019 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000019">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000017"/>
<obo:IAO_0000111 xml:lang="en">ontology module subsetted by OWL profile</obo:IAO_0000111>
<rdfs:label xml:lang="en">ontology module subsetted by OWL profile</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IAO_8000020 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000020">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000019"/>
<obo:IAO_0000111 xml:lang="en">EL++ ontology module</obo:IAO_0000111>
<rdfs:label xml:lang="en">EL++ ontology module</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IDO_0000450 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IDO_0000450">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000016"/>
<obo:IAO_0000111 xml:lang="en">pathogenic disposition</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A disposition to initiate processes that result in a disorder.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ido.owl"/>
<rdfs:label xml:lang="en">pathogenic disposition</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IDO_0000528 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IDO_0000528">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000111 xml:lang="en">pathogen</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A material entity with a pathogenic disposition.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ido.owl"/>
<rdfs:label xml:lang="en">pathogen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IDO_0000562 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IDO_0000562">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000111 xml:lang="en">antibacterial</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A material entity bearing an antibacterial disposition.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ido.owl"/>
<rdfs:label xml:lang="en">antibacterial</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IDO_0000586 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IDO_0000586">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000111 xml:lang="en">infection</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A part of an extended organism that itself has as part a population of one or more infectious agents and that (1) exists as a result of processes initiated by members of the infectious agent population and is (2) clinically abnormal in virtue of the presence of this infectious agent population, or (3) has a disposition to bring clinical abnormality to immunocompetent organisms of the same Species as the host (the organism corresponding to the extended organism) through transmission of a member or offspring of a member of the infectious agent population.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ido.owl"/>
<rdfs:label xml:lang="en">infection</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/IDO_0000666 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/IDO_0000666">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IDO_0000450"/>
<obo:IAO_0000111 xml:lang="en">human pathogenicity disposition</obo:IAO_0000111>
<obo:IAO_0000115>A disposition to initiate processes that result in a disorder in a human organism.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ido.owl"/>
<rdfs:label xml:lang="en">human pathogenicity disposition</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MRO_0000013 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MRO_0000013">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MRO_0001455"/>
<obo:IAO_0000111>HLA-DR protein complex</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/mro.owl"/>
<rdfs:label>HLA-DR protein complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MRO_0000966 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MRO_0000966">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MRO_0001759"/>
<obo:IAO_0000111>H2-Db protein complex</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/mro.owl"/>
<rdfs:label>H2-Db protein complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MRO_0000967 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MRO_0000967">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MRO_0001460"/>
<obo:IAO_0000111>H2-Dd protein complex</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/mro.owl"/>
<rdfs:label>H2-Dd protein complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MRO_0000971 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MRO_0000971">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MRO_0001461"/>
<obo:IAO_0000111>H2-IA protein complex</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/mro.owl"/>
<rdfs:label>H2-IA protein complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MRO_0000973 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MRO_0000973">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MRO_0000971"/>
<obo:IAO_0000111>H2-IAd protein complex</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/mro.owl"/>
<rdfs:label>H2-IAd protein complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MRO_0000975 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MRO_0000975">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MRO_0000971"/>
<obo:IAO_0000111>H2-IAg7 protein complex</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/mro.owl"/>
<rdfs:label>H2-IAg7 protein complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MRO_0000991 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MRO_0000991">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MRO_0001759"/>
<obo:IAO_0000111>H2-Kb protein complex</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/mro.owl"/>
<rdfs:label>H2-Kb protein complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MRO_0000992 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MRO_0000992">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MRO_0001460"/>
<obo:IAO_0000111>H2-Kd protein complex</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/mro.owl"/>
<rdfs:label>H2-Kd protein complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MRO_0000994 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MRO_0000994">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MRO_0001460"/>
<obo:IAO_0000111>H2-Ks protein complex</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/mro.owl"/>
<rdfs:label>H2-Ks protein complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MRO_0000997 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MRO_0000997">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MRO_0001460"/>
<obo:IAO_0000111>H2-Ld protein complex</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/mro.owl"/>
<rdfs:label>H2-Ld protein complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MRO_0001149 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MRO_0001149">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MRO_0001454"/>
<obo:IAO_0000111>HLA-C protein complex</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/mro.owl"/>
<rdfs:label>HLA-C protein complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MRO_0001167 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MRO_0001167">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MRO_0001455"/>
<obo:IAO_0000111>HLA-DP protein complex</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/mro.owl"/>
<rdfs:label>HLA-DP protein complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MRO_0001355 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MRO_0001355">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0042611"/>
<obo:IAO_0000111>MHC class I protein complex</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/mro.owl"/>
<rdfs:label>MHC class I protein complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MRO_0001356 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MRO_0001356">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0042611"/>
<obo:IAO_0000111>MHC class II protein complex</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/mro.owl"/>
<rdfs:label>MHC class II protein complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MRO_0001434 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MRO_0001434">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MRO_0001355"/>
<obo:IAO_0000111>cattle MHC class I protein complex</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/mro.owl"/>
<rdfs:label>cattle MHC class I protein complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MRO_0001435 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MRO_0001435">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MRO_0001356"/>
<obo:IAO_0000111>cattle MHC class II protein complex</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/mro.owl"/>
<rdfs:label>cattle MHC class II protein complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MRO_0001454 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MRO_0001454">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MRO_0001355"/>
<obo:IAO_0000111>human MHC class I protein complex</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/mro.owl"/>
<rdfs:label>human MHC class I protein complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MRO_0001455 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MRO_0001455">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MRO_0001356"/>
<obo:IAO_0000111>human MHC class II protein complex</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/mro.owl"/>
<rdfs:label>human MHC class II protein complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MRO_0001460 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MRO_0001460">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MRO_0001355"/>
<obo:IAO_0000111>mouse MHC class I protein complex</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/mro.owl"/>
<rdfs:label>mouse MHC class I protein complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MRO_0001461 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MRO_0001461">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MRO_0001356"/>
<obo:IAO_0000111>mouse MHC class II protein complex</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/mro.owl"/>
<rdfs:label>mouse MHC class II protein complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MRO_0001465 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MRO_0001465">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MRO_0001355"/>
<obo:IAO_0000111>pig MHC class I protein complex</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/mro.owl"/>
<rdfs:label>pig MHC class I protein complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MRO_0001498 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MRO_0001498">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0042611"/>
<obo:IAO_0000111>mouse MHC protein complex with H2-p haplotype</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/mro.owl"/>
<rdfs:label>mouse MHC protein complex with H2-p haplotype</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MRO_0001530 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MRO_0001530">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0042611"/>
<obo:IAO_0000111>HLA protein complex with A2 serotype</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/mro.owl"/>
<rdfs:label>HLA protein complex with A2 serotype</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MRO_0001533 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MRO_0001533">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0042611"/>
<obo:IAO_0000111>HLA protein complex with A24 serotype</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/mro.owl"/>
<rdfs:label>HLA protein complex with A24 serotype</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MRO_0001537 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MRO_0001537">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0042611"/>
<obo:IAO_0000111>HLA protein complex with A28 serotype</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/mro.owl"/>
<rdfs:label>HLA protein complex with A28 serotype</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MRO_0001538 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MRO_0001538">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0042611"/>
<obo:IAO_0000111>HLA protein complex with A29 serotype</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/mro.owl"/>
<rdfs:label>HLA protein complex with A29 serotype</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MRO_0001557 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MRO_0001557">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0042611"/>
<obo:IAO_0000111>HLA protein complex with B27 serotype</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/mro.owl"/>
<rdfs:label>HLA protein complex with B27 serotype</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MRO_0001622 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MRO_0001622">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0042611"/>
<obo:IAO_0000111>HLA protein complex with DQ3 serotype</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/mro.owl"/>
<rdfs:label>HLA protein complex with DQ3 serotype</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MRO_0001759 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MRO_0001759">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MRO_0001460"/>
<obo:IAO_0000111>mouse MHC class I protein complex with H2-b haplotype</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/mro.owl"/>
<rdfs:label>mouse MHC class I protein complex with H2-b haplotype</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MRO_0001790 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MRO_0001790">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MRO_0001355"/>
<obo:IAO_0000111>rat MHC class I protein complex</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/mro.owl"/>
<rdfs:label>rat MHC class I protein complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MRO_0001793 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MRO_0001793">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MRO_0001356"/>
<obo:IAO_0000111>rat MHC class II protein complex with RT1-A haplotype</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/mro.owl"/>
<rdfs:label>rat MHC class II protein complex with RT1-A haplotype</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MRO_0002026 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MRO_0002026">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MRO_0001460"/>
<obo:IAO_0000111>H2-Dq protein complex</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/mro.owl"/>
<rdfs:label>H2-Dq protein complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MRO_0002027 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MRO_0002027">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MRO_0001460"/>
<obo:IAO_0000111>H2-Kq protein complex</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/mro.owl"/>
<rdfs:label>H2-Kq protein complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_10090 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10090">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_39107"/>
<obo:IAO_0000111>Mus musculus</obo:IAO_0000111>
<obo:IAO_0000118>house mouse</obo:IAO_0000118>
<obo:IAO_0000118>mouse</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Mus musculus</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_10116 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10116">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_39107"/>
<obo:IAO_0000111>Rattus norvegicus</obo:IAO_0000111>
<obo:IAO_0000118>Norway rat</obo:IAO_0000118>
<obo:IAO_0000118>brown rat</obo:IAO_0000118>
<obo:IAO_0000118>rat</obo:IAO_0000118>
<obo:IAO_0000118>rats</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Rattus norvegicus</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_10239 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10239">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
<obo:IAO_0000111>Viruses</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Viruses</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_10358 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10358">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3044472"/>
<obo:IAO_0000111>Cytomegalovirus</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Cytomegalovirus</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_10376 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10376">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3044472"/>
<obo:IAO_0000111>human gammaherpesvirus 4</obo:IAO_0000111>
<obo:IAO_0000118>Epstein Barr virus</obo:IAO_0000118>
<obo:IAO_0000118>Epstein-Barr virus</obo:IAO_0000118>
<obo:IAO_0000118>Epstein-Barr virus EBV</obo:IAO_0000118>
<obo:IAO_0000118>Human herpesvirus 4</obo:IAO_0000118>
<obo:IAO_0000118>Human herpesvirus 4 (Epstein-Barr virus)</obo:IAO_0000118>
<obo:IAO_0000118>Human herpesvirus type 4</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>human gammaherpesvirus 4</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_10407 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10407">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2732514"/>
<obo:IAO_0000111>Hepatitis B virus</obo:IAO_0000111>
<obo:IAO_0000118>Human hepatitis B virus</obo:IAO_0000118>
<obo:IAO_0000118>hepatitis B virus (HBV)</obo:IAO_0000118>
<obo:IAO_0000118>hepatitis B virus HBV</obo:IAO_0000118>
<obo:IAO_0000118>hepatitis B virus, HBV</obo:IAO_0000118>
<obo:IAO_0000118>human hepatitis B virus HBV</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Hepatitis B virus</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_11050 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11050">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2732406"/>
<obo:IAO_0000111>Flaviviridae</obo:IAO_0000111>
<obo:IAO_0000118>Flavivirus (arbovirus group B)</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Flaviviridae</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_11646 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11646">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2732514"/>
<obo:IAO_0000111>Lentivirus</obo:IAO_0000111>
<obo:IAO_0000118>Lentivirinae</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Lentivirus</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_11676 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11676">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11646"/>
<obo:IAO_0000111>Human immunodeficiency virus 1</obo:IAO_0000111>
<obo:IAO_0000118>human immunodeficiency virus 1 HIV-1</obo:IAO_0000118>
<obo:IAO_0000118>human immunodeficiency virus HIV-1</obo:IAO_0000118>
<obo:IAO_0000118>human immunodeficiency virus type 1 HIV 1</obo:IAO_0000118>
<obo:IAO_0000118>human immunodeficiency virus type 1 HIV1</obo:IAO_0000118>
<obo:IAO_0000118>human immunodeficiency virus type 1, HIV-1</obo:IAO_0000118>
<obo:IAO_0000118>human immunodeficiency virus type I HIV-1</obo:IAO_0000118>
<obo:IAO_0000118>human immunodeficiency virus type-1 HIV-1</obo:IAO_0000118>
<obo:IAO_0000118>human immunodeficiency virus-1 HIV-1</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Human immunodeficiency virus 1</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_11709 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11709">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11646"/>
<obo:IAO_0000111>Human immunodeficiency virus 2</obo:IAO_0000111>
<obo:IAO_0000118>HIV type 2</obo:IAO_0000118>
<obo:IAO_0000118>Human immunodeficiency virus type 2</obo:IAO_0000118>
<obo:IAO_0000118>Human immunodeficiency virus-2</obo:IAO_0000118>
<obo:IAO_0000118>human immunodeficiency virus type 2 HIV-2</obo:IAO_0000118>
<obo:IAO_0000118>human immunodeficiency virus type 2, HIV-2</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Human immunodeficiency virus 2</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_117571 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_117571">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_7742"/>
<obo:IAO_0000111>Euteleostomi</obo:IAO_0000111>
<obo:IAO_0000118>bony vertebrates</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Euteleostomi</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_1206794 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1206794">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_33213"/>
<obo:IAO_0000111>Ecdysozoa</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Ecdysozoa</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_12637 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_12637">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11050"/>
<obo:IAO_0000111>Dengue virus</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Dengue virus</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_160 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_160">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2"/>
<obo:IAO_0000111>Treponema pallidum</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Treponema pallidum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_197562 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_197562">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_6656"/>
<obo:IAO_0000111>Pancrustacea</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Pancrustacea</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_2 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
<obo:IAO_0000111>Bacteria</obo:IAO_0000111>
<obo:IAO_0000118>eubacteria</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Bacteria</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_2157 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2157">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
<obo:IAO_0000111>Archaea</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Archaea</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_2559587 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2559587">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10239"/>
<obo:IAO_0000111>Riboviria</obo:IAO_0000111>
<obo:IAO_0000118>RNA viruses</obo:IAO_0000118>
<obo:IAO_0000118>RNA viruses and viroids</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Riboviria</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_2732406 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2732406">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2559587"/>
<obo:IAO_0000111>Kitrinoviricota</obo:IAO_0000111>
<obo:IAO_0000118>Tombus-Noda-like virus sp.</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Kitrinoviricota</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_2732514 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2732514">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2559587"/>
<obo:IAO_0000111>Revtraviricetes</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Revtraviricetes</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_2759 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2759">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
<obo:IAO_0000111>Eukaryota</obo:IAO_0000111>
<obo:IAO_0000118>eucaryotes</obo:IAO_0000118>
<obo:IAO_0000118>eukaryotes</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Eukaryota</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_3044472 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_3044472">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10239"/>
<obo:IAO_0000111>Orthoherpesviridae</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Orthoherpesviridae</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_3052230 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_3052230">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11050"/>
<obo:IAO_0000111>Hepacivirus hominis</obo:IAO_0000111>
<obo:IAO_0000118>Hepacivirus C</obo:IAO_0000118>
<obo:IAO_0000118>Hepatitis C virus</obo:IAO_0000118>
<obo:IAO_0000118>hepatitis C virus HCV</obo:IAO_0000118>
<obo:IAO_0000118>human hepatitis C virus</obo:IAO_0000118>
<obo:IAO_0000118>human hepatitis C virus HCV</obo:IAO_0000118>
<obo:IAO_0000118>human hepatitis virus C HCV</obo:IAO_0000118>
<obo:IAO_0000118>post-transfusion hepatitis non A non B virus</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Hepacivirus hominis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_314146 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_314146">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_40674"/>
<obo:IAO_0000111>Euarchontoglires</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Euarchontoglires</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_32523 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_32523">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_117571"/>
<obo:IAO_0000111>Tetrapoda</obo:IAO_0000111>
<obo:IAO_0000118>tetrapods</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Tetrapoda</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_32524 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_32524">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_32523"/>
<obo:IAO_0000111>Amniota</obo:IAO_0000111>
<obo:IAO_0000118>amniotes</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Amniota</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_33154 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_33154">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2759"/>
<obo:IAO_0000111>Opisthokonta</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Opisthokonta</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_33208 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_33208">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_33154"/>
<obo:IAO_0000111>Metazoa</obo:IAO_0000111>
<obo:IAO_0000118>metazoans</obo:IAO_0000118>
<obo:IAO_0000118>multicellular animals</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Metazoa</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_33213 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_33213">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_33208"/>
<obo:IAO_0000111>Bilateria</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Bilateria</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_3702 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_3702">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2759"/>
<obo:IAO_0000111>Arabidopsis thaliana</obo:IAO_0000111>
<obo:IAO_0000118>mouse-ear cress</obo:IAO_0000118>
<obo:IAO_0000118>thale cress</obo:IAO_0000118>
<obo:IAO_0000118>thale-cress</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Arabidopsis thaliana</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_37124 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_37124">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2732406"/>
<obo:IAO_0000111>Chikungunya virus</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Chikungunya virus</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_388799 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_388799">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11676"/>
<obo:IAO_0000111>HIV-1 group O</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>HIV-1 group O</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_39107 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_39107">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9989"/>
<obo:IAO_0000111>Murinae</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Murinae</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_40674 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_40674">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_32524"/>
<obo:IAO_0000111>Mammalia</obo:IAO_0000111>
<obo:IAO_0000118>mammals</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Mammalia</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_44689 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_44689">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2759"/>
<obo:IAO_0000111>Dictyostelium discoideum</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Dictyostelium discoideum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_4890 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_4890">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_33154"/>
<obo:IAO_0000111>Ascomycota</obo:IAO_0000111>
<obo:IAO_0000118>ascomycetes</obo:IAO_0000118>
<obo:IAO_0000118>sac fungi</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Ascomycota</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_4896 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_4896">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_4890"/>
<obo:IAO_0000111>Schizosaccharomyces pombe</obo:IAO_0000111>
<obo:IAO_0000118>fission yeast</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Schizosaccharomyces pombe</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_4932 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_4932">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_716545"/>
<obo:IAO_0000111>Saccharomyces cerevisiae</obo:IAO_0000111>
<obo:IAO_0000118>Saccharomyces cerevisiae 'var. diastaticus'</obo:IAO_0000118>
<obo:IAO_0000118>baker's yeast</obo:IAO_0000118>
<obo:IAO_0000118>brewer's yeast</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Saccharomyces cerevisiae</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_5140 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5140">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_716545"/>
<obo:IAO_0000111>Neurospora</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Neurospora</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_5820 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5820">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2759"/>
<obo:IAO_0000111>Plasmodium</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Plasmodium</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_6239 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_6239">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1206794"/>
<obo:IAO_0000111>Caenorhabditis elegans</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Caenorhabditis elegans</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_6656 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_6656">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1206794"/>
<obo:IAO_0000111>Arthropoda</obo:IAO_0000111>
<obo:IAO_0000118>arthropods</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Arthropoda</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_6668 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_6668">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197562"/>
<obo:IAO_0000111>Daphnia</obo:IAO_0000111>
<obo:IAO_0000118>common water fleas</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Daphnia</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_7147 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_7147">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197562"/>
<obo:IAO_0000111>Diptera</obo:IAO_0000111>
<obo:IAO_0000118>flies</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Diptera</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_7157 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_7157">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_7147"/>
<obo:IAO_0000111>Culicidae</obo:IAO_0000111>
<obo:IAO_0000118>mosquitos</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Culicidae</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_716545 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_716545">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_4890"/>
<obo:IAO_0000111>saccharomyceta</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>saccharomyceta</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_7227 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_7227">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_7147"/>
<obo:IAO_0000111>Drosophila melanogaster</obo:IAO_0000111>
<obo:IAO_0000118>fruit fly</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Drosophila melanogaster</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_7742 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_7742">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_33213"/>
<obo:IAO_0000111>Vertebrata <vertebrates></obo:IAO_0000111>
<obo:IAO_0000118>Vertebrata</obo:IAO_0000118>
<obo:IAO_0000118>vertebrates</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Vertebrata <vertebrates></rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_784 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_784">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2"/>
<obo:IAO_0000111>Orientia tsutsugamushi</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Orientia tsutsugamushi</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_7955 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_7955">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_117571"/>
<obo:IAO_0000111>Danio rerio</obo:IAO_0000111>
<obo:IAO_0000118>leopard danio</obo:IAO_0000118>
<obo:IAO_0000118>zebra danio</obo:IAO_0000118>
<obo:IAO_0000118>zebra fish</obo:IAO_0000118>
<obo:IAO_0000118>zebrafish</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Danio rerio</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_8353 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_8353">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_32523"/>
<obo:IAO_0000111>Xenopus <genus></obo:IAO_0000111>
<obo:IAO_0000118>Xenopus</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Xenopus <genus></rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_9031 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9031">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_32524"/>
<obo:IAO_0000111>Gallus gallus</obo:IAO_0000111>
<obo:IAO_0000118>Gallus domesticus</obo:IAO_0000118>
<obo:IAO_0000118>bantam</obo:IAO_0000118>
<obo:IAO_0000118>chicken</obo:IAO_0000118>
<obo:IAO_0000118>chickens</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Gallus gallus</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_9606 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9606">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_314146"/>
<obo:IAO_0000111>Homo sapiens</obo:IAO_0000111>
<obo:IAO_0000118>human</obo:IAO_0000118>
<obo:IAO_0000118>human being</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Homo sapiens</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/NCBITaxon_9989 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9989">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_314146"/>
<obo:IAO_0000111>Rodentia</obo:IAO_0000111>
<obo:IAO_0000118>rodent</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
<rdfs:label>Rodentia</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBA_0000001 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBA_0000001">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000019"/>
<obo:IAO_0000111>biological attribute</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/oba.owl"/>
<rdfs:label>biological attribute</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBA_2060180 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBA_2060180">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBA_0000001"/>
<obo:IAO_0000111>limb coordination efficacy</obo:IAO_0000111>
<obo:IAO_0000115>The process efficacy of a limb coordination.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/oba.owl"/>
<rdfs:label>limb coordination efficacy</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBA_2060181 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBA_2060181">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBA_2060180"/>
<obo:IAO_0000111>upper limb coordination efficacy</obo:IAO_0000111>
<obo:IAO_0000115>The process efficacy of a upper limb coordination.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/oba.owl"/>
<rdfs:label>upper limb coordination efficacy</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBA_2060182 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBA_2060182">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBA_2060180"/>
<obo:IAO_0000111>lower limb coordination efficacy</obo:IAO_0000111>
<obo:IAO_0000115>The process efficacy of a lower limb coordination.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/oba.owl"/>
<rdfs:label>lower limb coordination efficacy</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBA_2060184 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBA_2060184">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBA_0000001"/>
<obo:IAO_0000111>whole organism stability</obo:IAO_0000111>
<obo:IAO_0000115>The stability of a multicellular organism.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/oba.owl"/>
<rdfs:label>whole organism stability</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBA_2060185 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBA_2060185">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBA_0000001"/>
<obo:IAO_0000111>facial muscle performance</obo:IAO_0000111>
<obo:IAO_0000115>The functionality of a facial muscle.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/oba.owl"/>
<rdfs:label>facial muscle performance</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBA_2060186 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBA_2060186">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBA_0000001"/>
<obo:IAO_0000111>peripheral nervous system function</obo:IAO_0000111>
<obo:IAO_0000115>The functionality of a peripheral nervous system.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/oba.owl"/>
<rdfs:label>peripheral nervous system function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBA_2060187 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBA_2060187">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBA_0000001"/>
<obo:IAO_0000111>knee joint functionality</obo:IAO_0000111>
<obo:IAO_0000115>The functionality of a knee joint.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/oba.owl"/>
<rdfs:label>knee joint functionality</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBA_2060188 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBA_2060188">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBA_0000001"/>
<obo:IAO_0000111>ankle joint functionality</obo:IAO_0000111>
<obo:IAO_0000115>The functionality of a ankle joint.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/oba.owl"/>
<rdfs:label>ankle joint functionality</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBA_2060189 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBA_2060189">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBA_0000001"/>
<obo:IAO_0000111>tendon of biceps brachii functionality</obo:IAO_0000111>
<obo:IAO_0000115>The functionality of a tendon of biceps brachii.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/oba.owl"/>
<rdfs:label>tendon of biceps brachii functionality</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBA_2060190 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBA_2060190">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBA_0000001"/>
<obo:IAO_0000111>brachioradialis functionality</obo:IAO_0000111>
<obo:IAO_0000115>The functionality of a brachioradialis.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/oba.owl"/>
<rdfs:label>brachioradialis functionality</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000006 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000006">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000273"/>
<obo:IAO_0000111>role of being consumer safety officer</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Consumer safety officer; Consumer Safety Officer Positions at FDA http://69.20.19.211/jobs/cso.htm</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">Person charged with serving as CSO, FDA official who coordinates the review</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">the role of a human being that is realized by enforcing regulations to ensure consumer safety</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000117>Person:Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI, CDISC</obo:IAO_0000119>
<rdfs:label xml:lang="en">role of being consumer safety officer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000010 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000010">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
<obo:IAO_0000111 xml:lang="en">fluorescent reporter intensity</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A measurement datum that represents the output of a scanner measuring the intensity value for each fluorescent reporter.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">person:Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>group:OBI</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">From the DT branch: This term and definition were originally submitted by the community to our branch, but we thought they best fit DENRIE. However we see several issues with this. First of all the name 'probe' might not be used in OBI. Instead we have a 'reporter' role. Also, albeit the term 'probe intensity' is often used in communities such as the microarray one, the name 'probe' is ambiguous (some use it to refer to what's on the array, some use it to refer to what's hybed to the array). Furthermore, this concept could possibly be encompassed by combining different OBI terms, such as the roles of analyte, detector and reporter (you need something hybed to a probe on the array to get an intensity) and maybe a more general term for 'measuring intensities'. We need to find the right balance between what is consistent with OBI and combinations of its terms and what is user-friendly. Finally, note that 'intensity' is already in the OBI .owl file and is also in PATO. Why didn't OBI import it from PATO? This might be a problem.</obo:IAO_0000232>
<rdfs:label xml:lang="en">fluorescent reporter intensity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000011 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000011">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000059"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000104"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
<obo:IAO_0000111>planned process</obo:IAO_0000111>
<obo:IAO_0000112>Injecting mice with a vaccine in order to test its efficacy</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A process that realizes a plan which is the concretization of a plan specification.</obo:IAO_0000115>
<obo:IAO_0000116>'Plan' includes a future direction sense. That can be problematic if plans are changed during their execution. There are however implicit contingencies for protocols that an agent has in his mind that can be considered part of the plan, even if the agent didn't have them in mind before. Therefore, a planned process can diverge from what the agent would have said the plan was before executing it, by adjusting to problems encountered during execution (e.g. choosing another reagent with equivalent properties, if the originally planned one has run out.)</obo:IAO_0000116>
<obo:IAO_0000116>We are only considering successfully completed planned processes. A plan may be modified, and details added during execution. For a given planned process, the associated realized plan specification is the one encompassing all changes made during execution. This means that all processes in which an agent acts towards achieving some
objectives is a planned process.</obo:IAO_0000116>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>branch derived</obo:IAO_0000119>
<obo:IAO_0000232>6/11/9: Edited at workshop. Used to include: is initiated by an agent</obo:IAO_0000232>
<obo:IAO_0000232 xml:lang="en">This class merges the previously separated objective driven process and planned process, as they the separation proved hard to maintain. (1/22/09, branch call)</obo:IAO_0000232>
<rdfs:label xml:lang="en">planned process</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000014 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000014">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000017"/>
<obo:IAO_0000111>regulator role</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Fact sheet - Regulating the companies The role of the regulator. Ofwat is the economic regulator of the water and sewerage industry in England and Wales. http://www.ofwat.gov.uk/aptrix/ofwat/publish.nsf/Content/roleofregulator_factsheet170805</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a regulatory role involved with making and/or enforcing relevant legislation and governmental orders</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person:Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>regulator</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">regulator role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000015 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000015">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000005"/>
<obo:IAO_0000111 xml:lang="en">biological feature identification objective</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Biological_feature_identification_objective is an objective role carried out by the proposition defining the aim of a study designed to examine or characterize a particular biological feature.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Jennifer Fostel</obo:IAO_0000117>
<rdfs:label xml:lang="en">biological feature identification objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000016 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000016">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000017"/>
<obo:IAO_0000111 xml:lang="en">regulation-assigned role</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Approval letter</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Regulation-assigned role is a regulatory role defined by legislation or governmental orders</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Jennifer Fostel</obo:IAO_0000117>
<rdfs:label xml:lang="en">regulation-assigned role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000017 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000017">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<obo:IAO_0000111 xml:lang="en">regulatory role</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Regulatory agency, Ethics committee, Approval letter; example: Browse these EPA Regulatory Role subtopics http://www.epa.gov/ebtpages/enviregulatoryrole.html Feb 29, 2008</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a role which inheres in material entities and is realized in the processes of making, enforcing or being defined by legislation or orders issued by a governmental body.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">GROUP: Role branch</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI, CDISC</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">govt agents responsible for creating regulations; proxies for enforcing regulations. CDISC definition: regulatory authorities. Bodies having the power to regulate. NOTE: In the ICH GCP guideline the term includes the authorities that review submitted clinical data and those that conduct inspections. These bodies are sometimes referred to as competent</obo:IAO_0000232>
<rdfs:label xml:lang="en">regulatory role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000018 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000018">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000947"/>
<obo:IAO_0000111>material supplier role</obo:IAO_0000111>
<obo:IAO_0000112>Jackson Labs is an organization which provide mice as experimental material</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a role realized through the process of supplying materials such as animal subjects, reagents or other materials used in an investigation.</obo:IAO_0000115>
<obo:IAO_0000116>Supplier role is a special kind of service, e.g. biobank</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">PERSON:Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>material provider role</obo:IAO_0000118>
<obo:IAO_0000118>supplier</obo:IAO_0000118>
<rdfs:label xml:lang="en">material supplier role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000020 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000020">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000116"/>
<obo:IAO_0000111>contract research organization role</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a worker role of carrying out the study according to the protocol document or study plan delivered by the PI, under the control of the study director. This role cannot make decisions about the study execution</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>contract research organization</obo:IAO_0000118>
<rdfs:label xml:lang="en">contract research organization role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000021 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000021">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
<obo:IAO_0000111 xml:lang="en">list-mode data file</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">An example of a list-mode data file is a file following list-mode Flow Cytometry Standard (FCS) format. Since FCS files can be in histogram mode or list-mode we have to specify which data format specifically. List-mode format in the overwhelming (even universal) option used.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A list-mode data file is a binary digital entity where events are stored sequentially, parameter by parameter.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">One example of usage is in the context of flow cytometry, however is not restricted to this community and is more widely used, e.g. by imaging people.</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">person:Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>group:Flow Cytometry community</obo:IAO_0000119>
<rdfs:label xml:lang="en">list-mode data file</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000023 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000023">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000663"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000100"/>
<obo:IAO_0000111>classified data set</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A data set that is produced as the output of a class prediction data transformation and consists of a data set with assigned class labels.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: James Malone</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Monnie McGee</obo:IAO_0000117>
<obo:IAO_0000118>data set with assigned class labels</obo:IAO_0000118>
<rdfs:label xml:lang="en">classified data set</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000025 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000025">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>reference substance role</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Calibration standard, positive control substance, vehicle Good Laboratory Practices: Questions and Answers - Test Control and Reference Substance Characterization http://www.epa.gov/enforcement/monitoring/programs/fifra/glpqanda-character.html</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a role inhering in a material entity that is realized when characteristics or responses elicited by the substance are used for comparison or reference.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person:Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>reference substance</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">reference substance role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000026 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000026">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000250"/>
<obo:IAO_0000111>cytological stain role</obo:IAO_0000111>
<obo:IAO_0000112>haemotoxylin is a general purpose nuclear stain extracted from the wood of the logwood tree WEB: http://en.wikipedia.org/wiki/Haematoxylin</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A dye role that is realized when the stain is used to colour cells and or cellular components for the purposes of visualization</obo:IAO_0000115>
<obo:IAO_0000117>Person:Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Person:Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>cytological stain</obo:IAO_0000118>
<rdfs:label xml:lang="en">cytological stain role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000029 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000029">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0302886"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>centrifuge pellet role</obo:IAO_0000111>
<obo:IAO_0000112>Definition of pellet :the material concentrated at the bottom of a centrifuge tube after centrifugation. http://www.everythingbio.com/glos/definition.php?word=pellet</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">pellet role is a role which inheres in a material entity and is realized by a material separation process using gravitational force generated by a centrifuge in which the material bearing the pellet role is the heavier or heaviest component of the output material..</obo:IAO_0000115>
<obo:IAO_0000117>GROUP: Role branch</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000232>9Mar09 after discussion with process branch changed definition to include use of centrifuge;</obo:IAO_0000232>
<rdfs:label xml:lang="en">centrifuge pellet role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000032 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000032">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000116"/>
<obo:IAO_0000111>clinical research coordinator role</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a worker role comprised of handling the administrative duties of a trial or study.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person:Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>clinical research coordinator</obo:IAO_0000118>
<rdfs:label xml:lang="en">clinical research coordinator role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000034 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000034">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600014"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>supernatant role</obo:IAO_0000111>
<obo:IAO_0000112>Precipitation is the formation of a solid in a solution during a chemical reaction. When the reaction occurs, the solid formed is called the precipitate, and the liquid remaining above the solid is called the supernate. Wikipedia</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">supernatant role is a role which inheres in a material entity and is realized by a material separation process using gravitational force in which the material bearing the supernatant role is the liquid component of the output material.</obo:IAO_0000115>
<obo:IAO_0000117>GROUP: Role branch</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">supernatant role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000038 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000038">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000932"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000967"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000372"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600046"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>chromatography column</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Chromatography column in chemistry is a tube and contents (typically glass) used to purify individual chemical compounds from mixtures of compounds. It is often used for preparative applications on scales from micrograms up to kilograms.</obo:IAO_0000115>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Column_chromatography</obo:IAO_0000119>
<obo:IAO_0000232>open tracker https://sourceforge.net/tracker/index.php?func=detail&aid=2881353&group_id=177891&atid=886178</obo:IAO_0000232>
<rdfs:label>chromatography column</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000040 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000040">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">drug role</obo:IAO_0000111>
<obo:IAO_0000112>http://www.answers.com/topic/drug
1. A substance used in the diagnosis, treatment, or prevention of a disease or as a component of a medication.
2. Such a substance as recognized or defined by the U.S. Food, Drug, and Cosmetic Act.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a role borne by a molecular entity and is realized in a process of absorption by an organism alters, or effects (or is assumed to effect) a function(s) which inhere in an organism</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Role Branch</obo:IAO_0000117>
<obo:IAO_0000118>drug</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">OBI, CDISC</obo:IAO_0000119>
<rdfs:label xml:lang="en">drug role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000041 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000041">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000379"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>pump valve switch</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A pump valve switch is a cardinal part of a liquid chromatography instrument that controls the flow.</obo:IAO_0000115>
<obo:IAO_0000116>FG:I would assume this should be a pump valve control switch and it would not be specific to a liquid chromatography instrument</obo:IAO_0000116>
<obo:IAO_0000117>OBI Instrument branch</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>pump valve switch</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000043 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000043">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000105"/>
<obo:IAO_0000111 xml:lang="en">xenotransplantation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">is the transplantation of living cells, tissues or \norgans from one species to another such as from pigs to humans</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PlanAndPlannedProcess Branch</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">xenotransplantation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000044 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000044">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<obo:IAO_0000111 xml:lang="en">physical document</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">a book is a physical document</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A physical document is an object serving as a record of information by means of symbolic marks.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>GROUP: OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">physical document</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000045 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000045">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600009"/>
<obo:IAO_0000111 xml:lang="en">waiting</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A planned process where an agent does not take any new actions towards a particular objective for a period of time until a set of conditions is met.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON:Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">BP: I have doubts about the utility of this.</obo:IAO_0000232>
<obo:IAO_0000232 xml:lang="en">We need a better handling/modeling of time (January 2008)</obo:IAO_0000232>
<rdfs:label xml:lang="en">waiting</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000047 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000047">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000111 xml:lang="en">processed material</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Examples include gel matrices, filter paper, parafilm and buffer solutions, mass spectrometer, tissue samples</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">Is a material entity that is created or changed during material processing.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON: Alan Ruttenberg</obo:IAO_0000117>
<rdfs:label xml:lang="en">processed material</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000048 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000048">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000932"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002089"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000370"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000372"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000401"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>chromatography device</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that facilitates the separation of mixtures. The function of a chromatography device involves passing a mixture dissolved in a "mobile phase" through a stationary phase, which separates the analyte to be measured from other molecules in the mixture and allows it to be isolated.</obo:IAO_0000115>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000118>chromatography instrument</obo:IAO_0000118>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Chromatography</obo:IAO_0000119>
<obo:IAO_0000232>open tracker https://sourceforge.net/tracker/index.php?func=detail&aid=2881353&group_id=177891&atid=886178</obo:IAO_0000232>
<rdfs:label>chromatography device</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000049 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000049">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000345"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000361"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000364"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>mass spectrometer</obo:IAO_0000111>
<obo:IAO_0000112>LCQ Fleet Ion Trap MSn manufactured by thermo fisher scientific</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A mass spectrometer is an instrument which is used to measure the mass to charge ratio of ions. All mass spectrometers consist of three basic parts: an ion source, a mass analyzer, and a detector system. The stages within the mass spectrometer are: 1. Production of ions from the sample 2. Separation of ions with different masses 3. Detection of the number of ions of each mass produced 4.Collection of data to generate the mass spectrum</obo:IAO_0000115>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Mass_spectrometry</obo:IAO_0000119>
<rdfs:label>mass spectrometer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000050 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000050">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_platform</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A platform is an object_aggregate that is the set of instruments and software needed to perform a process. definition_source: OBI.</obo:IAO_0000115>
<obo:IAO_0000117>OBI Instrument branch</obo:IAO_0000117>
<obo:IAO_0000119>OBI Instrument branch</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_platform</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000051 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000051">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000932"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000048"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000049"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000372"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>liquid chromatography mass spectrometry platform</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A liquid chromatography mass spectrometry platform is a platform that is the collection of instrument, software and reagents needed to perform a liquid chromatography mass spectrometry protocol. definition_source: OBI.</obo:IAO_0000115>
<obo:IAO_0000117>OBI instrument branch</obo:IAO_0000117>
<obo:IAO_0000119>OBI Instrument branch</obo:IAO_0000119>
<rdfs:label>liquid chromatography mass spectrometry platform</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000052 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000052">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001034"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400147"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000401"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>microarray platform</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A microarray platform is a platform that contains the instruments, software and reagents needed to perform a microarray protocol. definition_source: OBI.</obo:IAO_0000115>
<obo:IAO_0000117>OBI Instrument branch</obo:IAO_0000117>
<obo:IAO_0000119>OBI Instrument branch</obo:IAO_0000119>
<rdfs:label>microarray platform</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000054 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000054">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
<obo:IAO_0000111 xml:lang="en">ratio of collected to emitted light</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">10%</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A measurement datum measuring the amount of light collected s compared to the total amount of emitted light in the detector component of a flow cytometer instrument. The datum has a qualitative role</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">person:Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">person:Kevin Clancy</obo:IAO_0000117>
<obo:IAO_0000119>Submitted by the Flow Cytometry community in DigitalEntity-FlowCytometry-2007-03-30.txt</obo:IAO_0000119>
<rdfs:label xml:lang="en">ratio of collected to emitted light</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000055 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000055">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000242"/>
<obo:IAO_0000111 xml:lang="en">software optimization objective</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Software_optimization is a software_testing_objective role describing a study designed to identify the best software or parameters of the software.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Jennifer Fostel</obo:IAO_0000117>
<rdfs:label xml:lang="en">software optimization objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000056 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000056">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000273"/>
<obo:IAO_0000111>notified body role</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">The role of notified bodies presentation: http://ec.europa.eu/enterprise/electr_equipment/emc/revision/notified_bodies.pdf</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Notified body is regulator of consumables and medical devices charged by the Competent Authority with verifying compliance of medical devices (not drugs) with the applicable Essential Requirements stated in the Medical Device Directive</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">Notified Body (NB). A private institution charged by the Competent Authority with verifying compliance of medical devices (not drugs) with the applicable Essential Requirements stated in the Medical Device Directive. This process, called Conformity Assessment, has EU-wide validity once completed by the NB.</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Person: Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>notified body</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">OBI, CDISC</obo:IAO_0000119>
<rdfs:label xml:lang="en">notified body role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000057 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000057">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000105"/>
<obo:IAO_0000111 xml:lang="en">allotransplantation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">is the transplantation of organs between members of the same species.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PlanAndPlannedProcess Branch</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">allotransplantation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000059 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000059">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>gamma counter</obo:IAO_0000111>
<obo:IAO_0000112>A Geiger counter</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A processed material which measures gamma radiation</obo:IAO_0000115>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Gamma_counter</obo:IAO_0000119>
<rdfs:label>gamma counter</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000060 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000060">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000102"/>
<obo:IAO_0000111>trial monitor role</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a responsible party involved in planning, overseeing the conduct of a study or study component, and interpreting data from a study</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person:Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>trial monitor</obo:IAO_0000118>
<obo:IAO_0000232 xml:lang="en">CDISC definition: Person employed by the sponsor or CRO who is responsible for determining that a trial is being conducted in accordance with the protocol and GCP guidance. NOTE: A monitor's duties may include, but are not limited to, helping to plan and initiate a trial, assessing the conduct of trials, and assisting in data analysis, interpretation and extrapolation. Clinical Research Associate: Primary representative of the sponsor; monitors progress of investigator sites participating in a clinical study.</obo:IAO_0000232>
<rdfs:label xml:lang="en">trial monitor role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000064 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000064">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000025"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>positive reference substance role</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">MMS mutagen</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a reference role in which the characteristics or responses elicited by the substance playing the reference substance role are used to establish a "100%" response</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>positive reference substance</obo:IAO_0000118>
<rdfs:label xml:lang="en">positive reference substance role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000065 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000065">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111 xml:lang="en">polyethylene glycol p-(1,1,3,3-tetramethylbutyl)-phenyl ether</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PMID: 30799. J Histochem Cytochem. 1978 Sep;26(9):696-712. Acid lipase: a histochemical and biochemical study using triton X100-naphtyl palmitate micelles.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">triton X100 is a chemical entity which belongs to the group of The pluronics which are triblock copolymers of ethylene oxide and propylene oxide. Triton x-100 is_used_as detergent due to its non-ionic surfactant properties</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">adapted from Wikipedia before possible import from CHEBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">polyethylene glycol p-(1,1,3,3-tetramethylbutyl)-phenyl ether</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000066 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000066">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000572"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000338"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000471"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000339"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">investigation</obo:IAO_0000111>
<obo:IAO_0000112>Lung cancer investigation using expression profiling, a stem cell transplant investigation, biobanking is not an investigation, though it may be part of an investigation</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">a planned process that consists of parts: planning, study design execution, documentation and which produce conclusion(s).</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<obo:IAO_0000232>Could add specific objective specification</obo:IAO_0000232>
<obo:IAO_0000232 xml:lang="en">Following OBI call November 2012,26th: it was decided there was no need for adding "achieves objective of drawing conclusion" as existing relations were providing equivalent ability. this note closes the issue and validates the class definition to be part of the OBI core
editor = PRS</obo:IAO_0000232>
<obo:OBI_0001847>study</obo:OBI_0001847>
<rdfs:label xml:lang="en">investigation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000067 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000067">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">evaluant role</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">When a specimen of blood is assayed for glucose concentration, the blood has the evaluant role. When measuring the mass of a mouse, the evaluant is the mouse. When measuring the time of DNA replication, the evaluant is the DNA. When measuring the intensity of light on a surface, the evaluant is the light source.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">a role that inheres in a material entity that is realized in an assay in which data is generated about the bearer of the evaluant role</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">Role call - 17nov-08: JF and MC think an evaluant role is always specified input of a process. Even in the case where we have an assay taking blood as evaluant and outputting blood, the blood is not the specified output at the end of the assay (the concentration of glucose in the blood is)</obo:IAO_0000116>
<obo:IAO_0000116 xml:lang="en">examples of features that could be described in an evaluant: quality.... e.g. "contains 10 pg/ml IL2", or "no glucose detected")</obo:IAO_0000116>
<obo:IAO_0000117>GROUP: Role Branch</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000232>Feb 10, 2009. changes after discussion at OBI Consortium Workshop Feb 2-6, 2009. accepted as core term.</obo:IAO_0000232>
<rdfs:label xml:lang="en">evaluant role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000068 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000068">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000202"/>
<obo:IAO_0000111>reporting party role</obo:IAO_0000111>
<obo:IAO_0000112>Person who prepares microarray data in MAGE-TAB format and submits to a database, such as ArrayExpress.</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">The first section has been pre-designated as the 'Reporting Party' section and should be filled with the Reporting Party's personal information. http://www.mercedsheriff.com/SelfReporting.htm</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a study personnel role played by a party who reports the outcome of a study component</obo:IAO_0000115>
<obo:IAO_0000116>MO:submitter mapped to this term. So, alternative term 'submitter' was added.</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>reporting party</obo:IAO_0000118>
<obo:IAO_0000118>submitter</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">reporting party role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000070 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000070">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000441"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000027"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/OBI_0000339"/>
<owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/OBI_0200000"/>
<owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/OBI_0600013"/>
<obo:IAO_0000111 xml:lang="en">assay</obo:IAO_0000111>
<obo:IAO_0000112>Assay the wavelength of light emitted by excited Neon atoms. Count of geese flying over a house.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A planned process that has the objective to produce information about a material entity (the evaluant) by examining it.</obo:IAO_0000115>
<obo:IAO_0000116>12/3/12: BP: the reference to the 'physical examination' is included to point out that a prediction is not an assay, as that does not require physical examiniation.</obo:IAO_0000116>
<obo:IAO_0000116>Discussion on OBI call 2023-05-01 resulted in an agreement to revise the textual definition of 'assay'. https://github.com/obi-ontology/obi/issues/1683.</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">PlanAndPlannedProcess Branch</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">measuring</obo:IAO_0000118>
<obo:IAO_0000118 xml:lang="en">scientific observation</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<obo:OBI_0001847>study assay</obo:OBI_0001847>
<obo:OBI_9991118>any method</obo:OBI_9991118>
<rdfs:label xml:lang="en">assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000071 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000071">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
<obo:IAO_0000111 xml:lang="en">quantitative confidence value</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A data item which is used to indicate the degree of uncertainty about a measurement.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">person:Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>group:OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">quantitative confidence value</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000073 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000073">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">sample preparation for assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A sample_preparation_for_assay is a protocol_application including material_enrollments and biomaterial_transformations. definition_source: OBI.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PlanAndPlannedProcess Branch</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">study</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">sample preparation for assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000075 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000075">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000300"/>
<obo:IAO_0000111 xml:lang="en">diagnosis textual entity</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">diagnosis is an assessment of a disease or injury, its likely prognosis and treatment.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Jennifer Fostel</obo:IAO_0000117>
<rdfs:label xml:lang="en">diagnosis textual entity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000076 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000076">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
<obo:IAO_0000111>unplanned occurrence effecting an investigation</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Earthquake that destroys the lab, an outside investigator discovering an adverse effect of the reagants used</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a process which is external in origin to the investigation that has an impact on the outcome.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">unplanned occurrence effecting an investigation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000078 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000078">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
<obo:IAO_0000111 xml:lang="en">eMedical record</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">An eMedical record is a digital document derived from a computer system used primarily for patient care in a clinical setting. Not required to be compliant with requirements of 21 CFR Part 11.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">person:Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000119>article-without-pmid-or-doi:CDISCglossary</obo:IAO_0000119>
<rdfs:label xml:lang="en">eMedical record</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000079 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000079">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<obo:IAO_0000111>culture medium</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">A growth medium or culture medium is a substance in which microorganisms or cells can grow. Wikipedia, growth medium, Feb 29, 2008</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">a processed material that provides the needed nourishment for microorganisms or cells grown in vitro.</obo:IAO_0000115>
<obo:IAO_0000116>changed from a role to a processed material based on on Aug 22, 2011 dev call. Details see the tracker item: http://sourceforge.net/tracker/?func=detail&aid=3325270&group_id=177891&atid=886178
Modification made by JZ.</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Person: Jennifer Fostel, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">culture medium</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000083 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000083">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
<obo:IAO_0000111 xml:lang="en">electronic case report tabulation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An electronic case report tabulation is a digital document containing tabular data about multiple trial participants which is part of a clinical regulatory submission. An eCRT has the property that it can be audited and compliant with requirements of 21 CFR Part 11 and has format suited to review by regulators.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">person:Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000119>CDISC glossary</obo:IAO_0000119>
<rdfs:label xml:lang="en">electronic case report tabulation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000084 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000084">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000836"/>
<obo:IAO_0000111>polystyrene tube</obo:IAO_0000111>
<obo:IAO_0000112>Polystyrene tubes can be used to contain tissue culture cells during centrifgation</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A polystyrene tube is a test tube made of polystyrene</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Chris Stoeckert</obo:IAO_0000119>
<rdfs:label>polystyrene tube</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000086 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000086">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003610"/>
<obo:IAO_0000111>reagent role</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Buffer, dye, a catalyst, a solvating agent.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A role inhering in a biological or chemical entity that is intended to be applied in a scientific technique to participate (or have molecular components that participate) in a chemical reaction that facilitates the generation of data about some entity distinct from the bearer, or the generation of some specified material output distinct from the bearer.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON:Matthew Brush</obo:IAO_0000117>
<obo:IAO_0000118>reagent</obo:IAO_0000118>
<obo:IAO_0000119>PERSON:Matthew Brush</obo:IAO_0000119>
<obo:IAO_0000232>Feb 10, 2009. changes after discussion at OBI Consortium Workshop Feb 2-6, 2009. accepted as core term.
May 28 2013. Updated definition taken from ReO based on discussions initiated in Philly 2011 workshop. Former defnition described a narrower view of reagents in chemistry that restricts bearers of the role to be chemical entities ("a role played by a molecular entity used to produce a chemical reaction to detect, measure, or produce other substances"). Updated definition allows for broader view of reagents in the domain of biomedical research to include larger materials that have parts that participate chemically in a molecular reaction or interaction.</obo:IAO_0000232>
<rdfs:comment>(copied from ReO)
Reagents are distinguished from instruments or devices that also participate in scientific techniques by the fact that reagents are chemical or biological in nature and necessarily participate in or have parts that participate in some chemical interaction or reaction during their intended participation in some technique. By contrast, instruments do not participate in a chemical reaction/interaction during the technique.
Reagents are distinguished from study subjects/evaluants in that study subjects and evaluants are that about which conclusions are drawn and knowledge is sought in an investigation - while reagents, by definition, are not. It should be noted, however, that reagent and study subject/evaluant roles can be borne by instances of the same type of material entity - but a given instance will realize only one of these roles in the execution of a given assay or technique. For example, taq polymerase can bear a reagent role or an evaluant role. In a DNA sequencing assay aimed at generating sequence data about some plasmid, the reagent role of the taq polymerase is realized. In an assay to evaluate the quality of the taq polymerase itself, the evaluant/study subject role of the taq is realized, but not the reagent role since the taq is the subject about which data is generated.
In regard to the statement that reagents are 'distinct' from the specified outputs of a technique, note that a reagent may be incorporated into a material output of a technique, as long as the IDENTITY of this output is distinct from that of the bearer of the reagent role. For example, dNTPs input into a PCR are reagents that become part of the material output of this technique, but this output has a new identity (ie that of a 'nucleic acid molecule') that is distinct from the identity of the dNTPs that comprise it. Similarly, a biotin molecule input into a cell labeling technique are reagents that become part of the specified output, but the identity of the output is that of some modified cell specimen which shares identity with the input unmodified cell specimen, and not with the biotin label. Thus, we see that an important criteria of 'reagent-ness' is that it is a facilitator, and not the primary focus of an investigation or material processing technique (ie not the specified subject/evaluant about which knowledge is sought, or the specified output material of the technique).</rdfs:comment>
<rdfs:label xml:lang="en">reagent role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000089 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000089">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000014"/>
<obo:IAO_0000111>role of regulator of chemical manufacturer</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">EPA; John Mollison is the registrar of chemical products in Tasmania, the body that administers the Act that regulates chemical use in that State. http://www.abc.net.au/rn/science/earth/stories/s1160346.htm</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a regulator involved with making and enforcing legislation and governmental orders relevant to chemical manufacture</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>regulator of chemical manufacture</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">role of regulator of chemical manufacturer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000091 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000091">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<obo:IAO_0000111>detector reagent role</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a role which inheres in a molecular entity and is realized by the process of recording or registering a stimulus.</obo:IAO_0000115>
<obo:IAO_0000116>19feb2009. not clear we need this term. originally if came from microarrays -- the probes on the array are termed detectors in some instances</obo:IAO_0000116>
<obo:IAO_0000119>One that detects, especially a mechanical, electrical, or chemical device that automatically identifies and records or registers a stimulus, such as an environmental change in pressure or temperature, an electric signal, or radiation from a radioactive material. http://www.answers.com/topic/detector 19feb2009</obo:IAO_0000119>
<rdfs:label xml:lang="en">detector reagent role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000092 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000092">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000016"/>
<obo:IAO_0000111>role of certified IRB professional</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">CIP= Certified IRB Professional; http://acronyms.thefreedictionary.com/Certified+IRB+Professional</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a role of which inheres in a Homo sapiens and realized during administration and oversight of the daily activities of Institutional Review Boards (IRBs) in the USA</obo:IAO_0000115>
<obo:IAO_0000117>Person:Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Person:Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>certified IRB professional</obo:IAO_0000118>
<obo:IAO_0000119>WEB: http://en.wikipedia.org/wiki/Certified_IRB_Professional</obo:IAO_0000119>
<rdfs:label xml:lang="en">role of certified IRB professional</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000093 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000093">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>patient role</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">a hospitalized person; a person with controlled diabetes; the patient's role http://www.fertilityjourney.com/testingAndDiagnosis/theRightDoctor/thePatientsRole/index.asp?C=55245395146924652778</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a role which inheres in a person and is realized by the process of being under the care of a physician or health care provider</obo:IAO_0000115>
<obo:IAO_0000116>See also OMRSE:00000011 'patient role'</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">GROUP:Role Branch</obo:IAO_0000117>
<obo:IAO_0000118>patient</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">OBI, CDISC</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">CDISC definition: patient. Person under a physician's care for a particular disease or condition. NOTE: A subject in a clinical trial is not necessarily a patient, but a patient in a clinical trial is a subject. See also subject, trial subject, healthy volunteer. Often used interchangeably</obo:IAO_0000232>
<rdfs:label xml:lang="en">patient role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000094 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000094">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
</owl:Restriction>
</rdfs:subClassOf>
<owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/OBI_0600010"/>
<obo:IAO_0000111>material processing</obo:IAO_0000111>
<obo:IAO_0000112>A cell lysis, production of a cloning vector, creating a buffer.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A planned process which results in physical changes in a specified input material</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON: Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Philippe Rocca Serra</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">material transformation</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">material processing</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000096 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000096">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000208"/>
<obo:IAO_0000111 xml:lang="en">protocol testing objective</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Protocol_testing_objective is a methodology_testing_objective role describing a study designed to examine the effects of using different protocols.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Jennifer Fostel</obo:IAO_0000117>
<rdfs:label xml:lang="en">protocol testing objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000097 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000097">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000471"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">study subject role</obo:IAO_0000111>
<obo:IAO_0000112>Human subjects in a clinical trial, rats in a toxicogenomics study, tissue cutlures subjected to drug tests, fish observed in an ecotoxicology study.
Parasite example: people are infected with a parasite which is then extracted; the particpant under investigation could be the parasite, the people, or a population of which the people are members, depending on the nature of the study.
Lake example: a lake could realize this role in an investigation that assays pollution levels in samples of water taken from the lake.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A role that is realized through the execution of a study design in which the bearer of the role participates and in which data about that bearer is collected.</obo:IAO_0000115>
<obo:IAO_0000116>A participant can realize both "specimen role" and "participant under investigation role" at the same time. However "participant under investigation role" is distinct from "specimen role", since a specimen could somehow be involved in an investigation without being the thing that is under investigation.</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">GROUP: Role Branch</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">Following OBI call November 2012,26th:
1. it was decided there was no need for moving the children class and making them siblings of study subject role.
2. it also settles the disambiguation about 'study subject'. This is about the individual participating in the investigation/study, Not the 'topic' (as in 'toxicity study') of the investigation/study
This note closes the issue and validates the class definition to be part of the OBI core
editor = PRS</obo:IAO_0000232>
<rdfs:label xml:lang="en">participant under investigation role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000100 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000100">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_role of being first subject treated</obo:IAO_0000111>
<obo:IAO_0000112>Rat 1A; first enrolled patient to receive treatment</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">First subject treated role is a study subject role borne by the subject realized in the application of the process specified in intervention study design with no previous study subject realizing the role prior in the study</obo:IAO_0000115>
<obo:IAO_0000117>Role Branch</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_role of being first subject treated</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000101 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000101">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
<obo:IAO_0000111 xml:lang="en">measured expression level</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Examples are quantified data from an expression microarray experiment, PCR measurements, etc.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A measurement datum that is the outcome of the quantification of an assay for the activity of a gene, or the number of RNA transcripts.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">person:Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>OBI Data Transformation branch</obo:IAO_0000119>
<rdfs:label xml:lang="en">measured expression level</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000102 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000102">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000202"/>
<obo:IAO_0000111>responsible party role</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">he THERAPIST has the ability to print a separate statement for the patient and each responsible party. http://www.beaverlog.com/therapist/ez_support/billing/responsible_party_statements.htm</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a study personnel role played by a party who is accountable for the execution of a study component and can make decisions about the conduct of the study</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>responsible party</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">responsible party role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000103 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000103">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000102"/>
<obo:IAO_0000111>principal investigator role</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a responsible party role played by a person responsible for the overall conduct of a study</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>principal investigator</obo:IAO_0000118>
<obo:IAO_0000232 xml:lang="en">CDISC definition: A person responsible for the conduct of the clinical trial at a trial site. If a trial is conducted by a team of individuals at a trial site, the investigator is the responsible leader of the team and may be called the principal investigator. 2. The individual principal investigator. 2. The individual under whose immediate direction the test article is administered or dispensed to, or used involving, a subject, or, in the event of an investigation conducted by a team of individuals, is See also sponsor-investigator.; Leiter der klinischen Prufung.Under the German Drug Law, the physician who is head of the clinical investigation (CDISC): coordinating investigator (CDISC) (also study coordinator, MUSC); sponsor-investigator. An individual who both initiates and conducts, alone or with others, a clinical trial, and under whose immediate direction the investigational product is administered to, dispensed to, or used by a subject.NOTE: The term does not include any person other than an individual, hence not a corporation, agency (CDISC)</obo:IAO_0000232>
<rdfs:label xml:lang="en">principal investigator role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000105 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000105">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">transplantation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">a protocol application to replace an organ or tissue of an organism</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PlanAndPlannedProcess Branch</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">transplantation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000109 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000109">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete biological vector role</obo:IAO_0000111>
<obo:IAO_0000112>1983 Sci. Amer. Jan. 58/2 Plasmids are routinely used as vectors for introducing foreign DNA into bacteria.</obo:IAO_0000112>
<obo:IAO_0000112>Some epidemiological aspects and vector role of tick infestation on layers in the Faisalabad district (Pakistan). http://journals.cambridge.org/action/displayAbstract;jsessionid=0373164489D00868AEEF2C556EB4FD29.tomcat1?fromPage=online&aid=624280</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a biological vector role is a material to be added role that is realized by the process of transmitting material to the organism that is the target of the transmission.</obo:IAO_0000115>
<obo:IAO_0000117>GROUP: Role Branch</obo:IAO_0000117>
<obo:IAO_0000119>OBI and Wikipedia</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete biological vector role</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000110 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000110">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000250"/>
<obo:IAO_0000111>pH indicator dye role</obo:IAO_0000111>
<obo:IAO_0000112>bromophenol blue has a pH indicator dye role</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">phenol red in RPMI; pH=4 indicator dye (also carries reference role)</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">the role of a dye that is realized when the dye is used in an experiment to measure the pH in a material entity</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000117>Person:Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000118>pH indicator dye</obo:IAO_0000118>
<rdfs:label xml:lang="en">pH indicator dye role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000112 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000112">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>specimen role</obo:IAO_0000111>
<obo:IAO_0000112>liver section; a portion of a culture of cells; a nemotode or other animal once no longer a subject (generally killed); portion of blood from a patient.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A role borne by a material entity that is obtained during a specimen collection process and that can be realized by performing measurements or observations on the specimen.</obo:IAO_0000115>
<obo:IAO_0000116>22Jun09. The definition includes whole organisms, and can include a human. The link between specimen role and study subject role has been removed. A specimen taken as part of a case study is not considered to be a population representative, while a specimen taken as representing a population, e.g. person taken from a cohort, blood specimen taken from an animal) would be considered a population representative and would also bear material sample role.</obo:IAO_0000116>
<obo:IAO_0000116>Note: definition is in specimen creation objective which is defined as an objective to obtain and store a material entity for potential use as an input during an investigation.</obo:IAO_0000116>
<obo:IAO_0000116 xml:lang="en">blood taken from animal: animal continues in study, whereas blood has role specimen.
something taken from study subject, leaves the study and becomes the specimen.</obo:IAO_0000116>
<obo:IAO_0000116 xml:lang="en">parasite example
- when parasite in people we study people, people are subjects and parasites are specimen
- when parasite extracted, they become subject in the following study
specimen can later be subject.</obo:IAO_0000116>
<obo:IAO_0000117>GROUP: Role Branch</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000233 rdf:resource="https://github.com/obi-ontology/obi/issues/1013"/>
<rdfs:label xml:lang="en">specimen role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000113 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000113">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000015"/>
<obo:IAO_0000111 xml:lang="en">sequence feature identification objective</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Sequence_feature_identification_objective is a biological_feature_identification_objective role describing a study designed to examine or characterize molecular features exhibited at the level of a macromolecular sequence, e.g. nucleic acid, protein, polysaccharide.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Jennifer Fostel</obo:IAO_0000117>
<rdfs:label xml:lang="en">sequence feature identification objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000115 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000115">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0500000"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000750"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000931"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
<obo:IAO_0000111>intervention design</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 18208636.Br J Nutr. 2008 Jan 22;:1-11.Effect of vitamin D supplementation on bone and vitamin D status among Pakistani immigrants in Denmark: a randomised double-blinded placebo-controlled intervention study.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">An intervention design is a study design in which a controlled process applied to the subjects (the intervention) serves as the independent variable manipulated by the experimentalist. The treatment (perturbation or intervention) defined can be defined as a combination of values taken by independent variable manipulated by the experimentalists are applied to the recruited subjects assigned (possibly by applying specific methods) to treatment groups. The specificity of intervention design is the fact that independent variables are being manipulated and a response of the biological system is evaluated via response variables as monitored by possibly a series of assays.</obo:IAO_0000115>
<obo:IAO_0000117>Philppe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>OBI branch derived</obo:IAO_0000119>
<rdfs:label>intervention design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000116 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000116">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000202"/>
<obo:IAO_0000111>worker role</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Public sector workers in states that run their own OSHA programs are covered by those states. http://www.osha.gov/as/opa/worker/index.html</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a personnel role played by a party who executes a component of the study plan; this can occur before, during, after or outside the study timeline</obo:IAO_0000115>
<obo:IAO_0000116>"executes the study plan" includes the suppliers and manufacturers of reagents and other materials used in the study</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Person:Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>worker</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">worker role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000117 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000117">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>Bernoulli trial</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">An assay where the output data is a datum with one of two values denoting success and failure.</obo:IAO_0000115>
<obo:IAO_0000117>PlanAndPlannedProcess Branch</obo:IAO_0000117>
<obo:IAO_0000119>OBI branch derived</obo:IAO_0000119>
<rdfs:label>Bernoulli trial</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000118 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000118">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000100"/>
<obo:IAO_0000111 xml:lang="en">gene list</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Gene lists may arise from analysis to determine differentially expressed genes, may be collected from the literature for involvement in a particular process or pathway (e.g., inflammation), or may be the input for gene set enrichment analysis.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A data set of the names or identifiers of genes that are the outcome of an analysis or have been put together for the purpose of an analysis.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">person:Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>group:OBI</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">kind of report. (alan) need to be careful to distinguish from output of a data transformation or calculation. A gene list is a report when it is published as such? Relates to question of whether report is a whole, or whether it can be a part of some other narrative object.</obo:IAO_0000232>
<rdfs:label xml:lang="en">gene list</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000119 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000119">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
<obo:IAO_0000111 xml:lang="en">number of particles in subset</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">500, 200, 0</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A measurement datum measuring the number of subjects in a defined subset in a flow cytometer instrument. The datum has a qualitative role</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">person:Kevin Clancy</obo:IAO_0000117>
<obo:IAO_0000119>Submitted by the Flow Cytometry community in DigitalEntity-FlowCytometry-2007-03-30.txt</obo:IAO_0000119>
<rdfs:label xml:lang="en">number of particles in subset</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000125 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000125">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
<obo:IAO_0000111 xml:lang="en">number of lost events electronic</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">74, 0, 14 events lost due to data acquisition electronic coincidence.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A measurement datum measuring the number of analysis events lost due to errors in data acquisition electronic coincidence in a flow cytometer instrument. The datum has a qualitative role.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">person:Kevin Clancy</obo:IAO_0000117>
<obo:IAO_0000119>Submitted by the Flow Cytometry community in DigitalEntity-FlowCytometry-2007-03-30.txt</obo:IAO_0000119>
<rdfs:label xml:lang="en">number of lost events electronic</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000129 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000129">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000025"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000818"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">calibration substance role</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">pH buffer used to calibrate a pH meter bears a calibration substance role</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A reference substance role that is realized when characteristics or responses elicited by the bearer are used to ensure an instrument is within protocol specification of accuracy or performance</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Jennifer Fostel</obo:IAO_0000117>
<rdfs:label xml:lang="en">calibration substance role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000131 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000131">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000015"/>
<obo:IAO_0000111 xml:lang="en">molecular feature identification objective</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Molecular_feature_identification_objective is a biological_feature_identification_objective role describing a study designed to examine or characterize molecular features of a biological system, e.g. expression profiling, copy number of molecular components, epigenetic modifications.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Jennifer Fostel</obo:IAO_0000117>
<rdfs:label xml:lang="en">molecular feature identification objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000134 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000134">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000208"/>
<obo:IAO_0000111 xml:lang="en">hardware testing objective</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Hardware_testing_objective is a methodology_testing_objective role describing a study designed to examine the effects of using different hardware, e.g. scanner.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Jennifer Fostel</obo:IAO_0000117>
<rdfs:label xml:lang="en">hardware testing objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000136 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000136">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001034"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000401"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>incubator</obo:IAO_0000111>
<obo:IAO_0000112>Incubators are used in microbiology for culturing (growing) bacteria and other microorganisms. Incubators in tissue culture rooms are used for culturing stem cells, lymphocytes, skin fibroblasts and other types of cells</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device in which environmental conditions (light, photoperiod, temperature, humidity, etc.) can be controlled</obo:IAO_0000115>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000119>http://www.medterms.com/script/main/art.asp?articlekey=18426</obo:IAO_0000119>
<rdfs:label>incubator</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000140 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000140">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_label role</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000115 xml:lang="en">Label role is a role which inheres in a material entity and which is realized in a detection of label assay</obo:IAO_0000115>
<obo:IAO_0000117>Role Branch</obo:IAO_0000117>
<obo:IAO_0000118>label</obo:IAO_0000118>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/OBI_0002743"/>
<rdfs:label>obsolete_label role</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000143 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000143">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000220"/>
<obo:IAO_0000111>baseline participant role</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Subject at time = 0; subject before a stress test.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a reference participant role which is realized by making the reference to qualities at the start of the study or intervention</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>baseline participant</obo:IAO_0000118>
<rdfs:label xml:lang="en">baseline participant role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000144 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000144">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000060"/>
<obo:IAO_0000111>role of independent data monitoring committee</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a trial monitor role charged recommending whether to continue, modify, or end the trial</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>independent data monitoring committee</obo:IAO_0000118>
<rdfs:label xml:lang="en">role of independent data monitoring committee</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000145 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000145">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000116"/>
<obo:IAO_0000111>pathologist role</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a worker role of being responsible for making the histopathology diagnoses associated with data from a study; this activity occurs outside the study timeline</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person:Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>Pathologist</obo:IAO_0000118>
<rdfs:label xml:lang="en">pathologist role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000146 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000146">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000967"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000370"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>supernatant collection system harvesting frame</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that is designed for collecting 90% of the supernatant in a microplate well and separating the living cell with no stress, eliminating centrifugation and other similar techniques. It can be used in a variety of release assays with different radioactive isotopes, such as Cr51 or I125.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>google</obo:IAO_0000119>
<rdfs:label>supernatant collection system harvesting frame</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000151 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000151">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000932"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000378"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>filter paper</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device manufacture with the intent to provide a porous unsized paper used for filtering.</obo:IAO_0000115>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000119>sep:00107</obo:IAO_0000119>
<rdfs:label>filter paper</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000153 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000153">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:minCardinality rdf:datatype="http://www.w3.org/2001/XMLSchema#nonNegativeInteger">2</owl:minCardinality>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000079"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100060"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">cell co-culturing</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Culturing cytotoxic T-lymphocytes together with target cells in order to study lysis of the target cells. See chromium_release_assay</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A material combination in which cell cultures of two or more different types are are combined and allowed to culture as one.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PlanAndPlannedProcess Branch</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">cell co-culturing</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000154 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000154">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000014"/>
<obo:IAO_0000111>role of Institutional Review Board</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">An institutional review board/independent ethics committee (IRB/IEC) (also known as ethical review board) is a group that has been formally designated to approve, monitor, and review biomedical and behavioral research involving humans with the alleged aim to protect the rights and welfare of the subjects. Wikipedia March 2008</obo:IAO_0000112>
<obo:IAO_0000112>Animal protocol review board</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">the role of a organization that is realized by members reviewing study designs for their agreement with regulations</obo:IAO_0000115>
<obo:IAO_0000117>Person:Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Person:Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>Internal Review Board</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">OBI, CDISC</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">CDISC definition: institutional review board; independent ethics committee (IEC). An independent body (a review board or a committee, institutional, regional, national, or supranational) constituted of medical/scientific professionals and non-scientific members, whose responsibility it is to ensure the protection of the rights, safety and well-being of human subjects involved in a trial.</obo:IAO_0000232>
<rdfs:label xml:lang="en">role of Institutional Review Board</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000158 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000158">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
<obo:IAO_0000111 xml:lang="en">eSource document</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">an eSource document is a digital document consisting of a logical collection of Source data and other eSource documents that can be presented in an ordered way and capture the time of completion, change, and any signatures</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">person:Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000119>article-without-pmid-or-doi:CDISCglossary</obo:IAO_0000119>
<rdfs:label xml:lang="en">eSource document</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000161 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000161">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000220"/>
<obo:IAO_0000111>crossover population role</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a role realized when a participant serves as reference to itself</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>crossover population</obo:IAO_0000118>
<rdfs:label xml:lang="en">crossover population role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000162 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000162">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000204"/>
<obo:IAO_0000111>complete nutrient role</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Rat chow; RPMI medium + serum; use example: CNS17 (Complete Nutrient System) Grow 3-2-4, http://www.kalyx.com/store/proddetail.cfm/ItemID/552307/CategoryID/12000/SubCatID/2755/file.htm</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A nutrient role that inheres in a material entity and is realized in the use of that material entity by an organism to provide all needed nourishment.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>complete nutrient</obo:IAO_0000118>
<rdfs:label xml:lang="en">complete nutrient role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000163 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000163">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002743"/>
<obo:IAO_0000111 xml:lang="en">radiolabel role</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a molecular label role which inheres in a material entity which is realized by the process of radioactivity detection</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">radiolabel</obo:IAO_0000118>
<rdfs:label xml:lang="en">radiolabel role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000164 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000164">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000731"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600064"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000731"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">cDNA library</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PMID:6110205. collection of cDNA derived from mouse splenocytes.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Mixed population of cDNAs (complementaryDNA) made from mRNA from a defined source, usually a specific cell type. This term should be associated only to nucleic acid interactors not to their proteins product. For instance in 2h screening use living cells (MI:0349) as sample process.
ALT DEF (PRS):: a cDNA library is a collection of host cells, typically E.Coli cells but not exclusively. modified by transfer of plasmid DNA molecule used as vector containing a fragment or totality of cDNA molecule (the insert) . cDNA library may have an array of role and applications.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON: Luisa Montecchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">PERSON: Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">GROUP: PSI</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">PRS: 22022008. class moved under population,
modification of definition and replacement of biomaterials in previous definition with 'material'
addition of has_role restriction</obo:IAO_0000232>
<rdfs:label xml:lang="en">clonal cDNA library</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000167 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000167">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
<obo:IAO_0000111 xml:lang="en">electronic case report form</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An electronic case report form is a digital document used to record all of the protocol required information to be reported for each trial subject. An eCRF has the property that it can be audited and compliant with requirements of 21 CFR Part 11.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">person:Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000119>CDISC glossary</obo:IAO_0000119>
<rdfs:label xml:lang="en">electronic case report form</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000169 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000169">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000214"/>
<obo:IAO_0000111>placebo role</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Pill consisting of inert materials</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a negative reference substance is a reference role in which the substance playing the reference substance role is physically similar in appearance to the test substance</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person:Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>placebo</obo:IAO_0000118>
<obo:IAO_0000232 xml:lang="en">CDISC definition placebo. A pharmaceutical preparation that does not contain the investigational agent. In blinded studies, it is generally prepared to be physically indistinguishable from the preparation containing the investigational product.</obo:IAO_0000232>
<rdfs:label xml:lang="en">placebo role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000171 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000171">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000105"/>
<obo:IAO_0000111 xml:lang="en">autotransplantation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">is the transplantation of tissue from one part of \nthe body to another in the same individual. )</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PlanAndPlannedProcess Branch</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">autotransplantation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000172 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000172">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
<obo:IAO_0000111 xml:lang="en">parameter threshold</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">0.01, 0.03</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A measurement datum measuring the minimal signal that must be detected to generate an electrical event, as compared to the maximal detected signal in a flow cytometer instrument. The datum has a qualitative role</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">person:Kevin Clancy</obo:IAO_0000117>
<obo:IAO_0000119>Submitted by the Flow Cytometry community in DigitalEntity-FlowCytometry-2007-03-30.txt</obo:IAO_0000119>
<rdfs:label xml:lang="en">parameter threshold</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000174 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000174">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<obo:IAO_0000111>study group role</obo:IAO_0000111>
<obo:IAO_0000112>The group of randomized participants that are assigned to a treatment arm of the trial</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a study population role where the bearer is a population of material entities and the role is realized in the implementation of a study design wherein the entities bearing the study population role are observed or subjected to intervention according to the study design and are biological replicates, i.e. they receive the same treatment under the protocol</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>study group population</obo:IAO_0000118>
<rdfs:label xml:lang="en">study group role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000175 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000175">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000071"/>
<obo:IAO_0000111 xml:lang="en">p-value</obo:IAO_0000111>
<obo:IAO_0000112>PMID:19696660
in contrast to the in-vivo data AT-III increased significantly from
113.5% at baseline to 117% after 4 days (n = 10, P-value= 0.02; Table 2).</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000121"/>
<obo:IAO_0000115 xml:lang="en">A quantitative confidence value that represents the probability of obtaining a result at least as extreme as that actually obtained, assuming that the actual value was the result of chance alone.</obo:IAO_0000115>
<obo:IAO_0000116>May be outside the scope of OBI long term, is needed so is retained</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">PERSON:Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>WEB: http://en.wikipedia.org/wiki/P-value</obo:IAO_0000119>
<rdfs:label xml:lang="en">p-value</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000181 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000181">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000111 xml:lang="en">population</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PMID12564891. Environ Sci Technol. 2003 Jan 15;37(2):223-8. Effects of historic PCB exposures on the reproductive success of the Hudson River striped bass population.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">a population is a collection of individuals from the same taxonomic class living, counted or sampled at a particular site or in a particular area</obo:IAO_0000115>
<obo:IAO_0000116>1/28/2013, BP, on the call it was raised that we may want to switch to an external ontology for all populatin terms:
http://code.google.com/p/popcomm-ontology/</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">PERSON: Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">adapted from Oxford English Dictionnary</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">rem1: collection somehow always involve a selection process</obo:IAO_0000232>
<rdfs:label xml:lang="en">population</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000182 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000182">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003117"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000566"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000566"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001155"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003117"/>
<obo:IAO_0000111>NMR 3D molecular structure determination assay</obo:IAO_0000111>
<obo:IAO_0000112>Determining the binding of epitope-specific nanobody cAb-HuL5 to wild type human lysozyme by chemical shift perturbations in NMR spectra (Erwin De Genst, J Phys Chem B 2013).</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A 3D molecular structure determination assay that uses magnetic properties of atomic nuclei to determine the 3D structure and dynamics of molecules in the input sample.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000117>PlanAndPlannedProcess Branch</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>NMR 3D molecular structure determination assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000185 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000185">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000101"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>imaging assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">An assay that produces a picture of an entity.</obo:IAO_0000115>
<obo:IAO_0000117>PlanAndPlannedProcess Branch</obo:IAO_0000117>
<obo:IAO_0000119>OBI branch derived</obo:IAO_0000119>
<rdfs:label>imaging assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000186 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000186">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000096"/>
<obo:IAO_0000111 xml:lang="en">protocol optimization objective</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Protocol_optimization is a protocol_testing_objective role describing a study designed to identify the best protocol. This may be carried out by comparing different protocols or by modifying the parameters used within a single protocol.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Jennifer Fostel</obo:IAO_0000117>
<rdfs:label xml:lang="en">protocol optimization objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000188 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000188">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000116"/>
<obo:IAO_0000111>role of pathology review board</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a worker role comprised of providing a confirmed and consensus diagnosis for histopathology results obtained during the investigation</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>pathology review board</obo:IAO_0000118>
<rdfs:label xml:lang="en">role of pathology review board</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000192 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000192">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000967"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000370"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>microtiter plate</obo:IAO_0000111>
<obo:IAO_0000112>A microtiter plate with 6, 24, 96, 384 or 1536 sample wells used in the enzyme-linked immunosorbent assay (ELISA)</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A microtiter_plate is a flat plate with multiple wells used as small test tubes.</obo:IAO_0000115>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000118>microplate</obo:IAO_0000118>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Microtiter_plate</obo:IAO_0000119>
<rdfs:label>microtiter plate</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000196 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000196">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000016"/>
<obo:IAO_0000111>role of impartial witness</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">According to GCP , an impartial witness should be present for an
illiterate subject. PharmPK Discussion, http://www.boomer.org/pkin/PK06/PK2006253.html</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a role which inheres in a Homo sapiens and is realized during a clinical trial - the impartial witness is independent of the trial and cannot be unfairly influenced by people involved with the trial</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">impartial witness. A person, who is independent of the trial, who cannot be unfairly influenced by people involved with the trial, who attends the informed consent process if the subject or the subject's legally acceptable representative cannot read, and who</obo:IAO_0000116>
<obo:IAO_0000117>Person: Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Person: Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>impartial witness</obo:IAO_0000118>
<rdfs:label xml:lang="en">role of impartial witness</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_00001975 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_00001975">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000690"/>
<obo:IAO_0000111 xml:lang="en">chromatin immunoprecipitation</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Yang et al, Int J Clin Exp Pathol. 2015; 8(3): 2746–275 PMID:26045780. Cells were lysed and sonicated to shear DNA to lengths between 200-1000 bp. The sample was then incubated with antibodies against Acety-H3 to immunoprecipitate protein-DNA complexes using protein A agarose beads. The isolated protein-DNA complexes were treated with proteinase K digestion to remove histones. QPCR was then performed using primers specific for TGF-β1, MMP-9 and PI3K promoters at 95°C for 5 min, followed by 40 cycles at 95 °C for 20 s, 58°C for 20 s, and 72°C for 20 s. Each QPCR reaction was repeated in triplicate. QPCR was followed by a melt curve analysis to determine the reaction specificity. The relative gene expression was calculated using 2-ΔΔCt method.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An immunoprecipitation in which chromatin (i.e. packaged DNA which can include protein and RNA complexes) is cut into short regions, reversibly cross linked, and antibodies or tags are used to select for pieces of chromatin with desired characteristics.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Bjoern Peters, Randi Vita, James A. Overton</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">ChIP</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">chromatin immunoprecipitation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000198 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000198">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000220"/>
<obo:IAO_0000111>biological replicate role</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">A member of a dose-time group; a patient in a given arm of a trial</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a reference participant role realized by equivalent treatment of participants</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person:Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>biological replicate</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">biological replicate role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000201 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000201">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000053"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0001741"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000053"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0001741"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>radioactivity detection</obo:IAO_0000111>
<obo:IAO_0000112>Placing the evaluant input material close to a scintillation counter which emits light upon being hit with alpha/beta/gamma radiation and counting the frequency of light blasts to determine the radioactivity of the input material.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures the amount of radiation in the radioactive spectrum (alpha, beta or gamma rays) emitted from an input material.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000117>PlanAndPlannedProcess Branch</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>radioactivity detection</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000202 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000202">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000023"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000053"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000059"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000833"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000066"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000066"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>investigation agent role</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">The person perform microarray experiments and submit microarray results (including raw data, processed data) with experiment description to ArrayExpress.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A role borne by an entity and that is realized in a process that is part of an investigation in which an objective is achieved. These processes include, among others: planning, overseeing, funding, reviewing.</obo:IAO_0000115>
<obo:IAO_0000116>Implementing a study means carrying out or performing the study and providing reagents or other materials used in the study and other tasks without which the study would not happen.</obo:IAO_0000116>
<obo:IAO_0000116>Philly2013: Historically, this role would have been borne only by humans or organizations. However, we now also want to enable representing investigations run by robot scientists such as ADAM (King et al, Science, 2009)</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">GROUP: Role Branch</obo:IAO_0000117>
<obo:IAO_0000118>investigator</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">OBI</obo:IAO_0000119>
<obo:IAO_0000232>Feb 10, 2009. changes after discussion at OBI Consortium Workshop Feb 2-6, 2009. accepted as core term.</obo:IAO_0000232>
<obo:OBI_0001847>study person role</obo:OBI_0001847>
<rdfs:comment>Philly2013: Historically, this role would have been borne only by humans or organizations. However, we now also want to enable investigations run by robot scientists such as ADAM (King et al, Science, 2009)</rdfs:comment>
<rdfs:label>investigation agent role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000204 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000204">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>nutrient role</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Luria broth; vitamin A; A nutrient is a substance used in an organism's metabolism which must be taken in from the environment. Wikipedia.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a role that inheres in a material entity and is realized in the use of that material entity by an organism when it is used in that organism's metabolism and provides nourishment.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">GROUP: Role branch</obo:IAO_0000117>
<obo:IAO_0000118>nutrient</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">Wikipedia, feb 29, 2008</obo:IAO_0000119>
<obo:IAO_0000232>19 Feb 2009; old def: A nutrient role is a role played by a substance used in an organism's metabolism which is taken in from the environment and provides nourishment.</obo:IAO_0000232>
<rdfs:label xml:lang="en">nutrient role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000205 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000205">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_dropout role</obo:IAO_0000111>
<obo:IAO_0000112>Escaped rat; human who moved to another city. Rat which escapes part way through a study; a human study participant who moved to another city before the study was completed (and stopped participating in the study)</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Dropout is a study subject role borne by an entity realized by a process of leaving the study earlier than the protocol specified and where the bearer of the dropout role had been borne study subject role prior to bearing dropout role.</obo:IAO_0000115>
<obo:IAO_0000117>Role Branch</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_dropout role</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000207 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000207">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete health care provider role</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a worker role of providing medical care either within or outside the study timeline</obo:IAO_0000115>
<obo:IAO_0000117>Person:Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>health care provider</obo:IAO_0000118>
<obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/OMRSE_00000012"/>
<rdfs:label>obsolete health care provider role</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000208 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000208">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000005"/>
<obo:IAO_0000111 xml:lang="en">methodology testing objective</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Methodology_testing_objective is an objective role carried out by a proposition defining the aim of the study is to examine the effect of using different methodologies.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Jennifer Fostel</obo:IAO_0000117>
<rdfs:label xml:lang="en">methodology testing objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000210 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000210">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
<obo:IAO_0000111 xml:lang="en">analytical cytology data file</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">FCS file, ACS file, foo.fcs, foo.asc</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A digital entity intended to capture data in analytical cytology domain.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">person:Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>group:Flow Cytometry community</obo:IAO_0000119>
<rdfs:label xml:lang="en">analytical cytology data file</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000211 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000211">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000116"/>
<obo:IAO_0000111>proxy respondent role</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Proxy respondent is a worker role of describing patient's symptoms or condition to medical personnel</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>proxy respondent</obo:IAO_0000118>
<rdfs:label xml:lang="en">proxy respondent role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000213 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000213">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
<obo:IAO_0000111 xml:lang="en">fluorescence compensation matrix</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">((1.053096, -0.22476), (-0.24877, 1.053096))</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A fluorescence compensation matrix is a square matrix which is used as the left multiplier of the vector of fluorescence values while performing digital fluorescence compensation. Also, fluorescence compensation matrix is the inverse of the fluorescence spillover matrix.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">person:Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>group:Flow Cytometry community</obo:IAO_0000119>
<rdfs:label xml:lang="en">fluorescence compensation matrix</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000214 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000214">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000025"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>negative reference substance role</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Saline solution</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a reference role in which the characteristics or responses elicited by the substance playing the reference substance role are used to establish a "no effect" response</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>negative reference substance</obo:IAO_0000118>
<rdfs:label xml:lang="en">negative reference substance role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000215 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000215">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000016"/>
<obo:IAO_0000111>role of legally acceptable representative</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Parent of minor patient; Definition of legally acceptable representative
An individual or juridicial or other body authorized under applicable law to consent, on behalf of a prospective subject, to the subject`s participation in the clinical trial. http://www.geneed.com/website/catalog/glossary_search.php?id=2134&search_term=legally%20acceptable%20representative&select=TRUE</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a role which inheres in a human or organization who are able subject to applicable law to consent, on behalf of a prospective subject, to the subject`s participation in as clinical trial.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">legally acceptable representative. An individual or juridical or other body authorized under applicable law to consent, on behalf of a prospective subject, to the subject's participation in the clinical trial. [ICH, E6 Glossary]</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Person: Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000117>Person:Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000118>legally acceptable representative</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">OBI, CDISC</obo:IAO_0000119>
<rdfs:label xml:lang="en">role of legally acceptable representative</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000218 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000218">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000088"/>
<obo:IAO_0000111 xml:lang="en">investigation results report</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">An investigation report is a report on the results of an investigation.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">person:Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>group:OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">investigation results report</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000219 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000219">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000015"/>
<obo:IAO_0000111 xml:lang="en">cellular feature identification objective</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Cellular_feature_identification_objective is a biological_feature_identification_objective role describing a study designed to examine or characterize a biological feature monitored at the cellular level, e.g. stage of cell cycle, stage of differentiation.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Jennifer Fostel</obo:IAO_0000117>
<rdfs:label xml:lang="en">cellular feature identification objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000220 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000220">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000097"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100026"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100051"/>
</owl:unionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>reference subject role</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Saline treated rat; one of three identically-treated subjects</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a reference subject role which inheres in an organism or entity of organismal origin so that the characteristics or responses of the participant playing the reference participant role are used for comparison or reference</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>reference participant</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">reference subject role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000221 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000221">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000250"/>
<obo:IAO_0000111>vital dye role</obo:IAO_0000111>
<obo:IAO_0000112>typtan blue has a vital dye</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A dye role that is realized when used to detect live cells in an experiment</obo:IAO_0000115>
<obo:IAO_0000116>2009-11-10. Tracker: https://sourceforge.net/tracker/?func=detail&aid=2893048&group_id=177891&atid=886178</obo:IAO_0000116>
<obo:IAO_0000117>Person: Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Person: Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>vital dye</obo:IAO_0000118>
<rdfs:label xml:lang="en">vital dye role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000223 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000223">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_blinded medication role</obo:IAO_0000111>
<obo:IAO_0000112>115 patients received ipilimumab and blinded medication</obo:IAO_0000112>
<obo:IAO_0000112>Inert pill shaped like aspirin tablet</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Is a role which inheres in a material entity which is manufactured to be similar in appearance to a test material entity in e.g. a clinical trial to prevent participants from detecting which is the active and inactive substance</obo:IAO_0000115>
<obo:IAO_0000117>Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000117>Person:Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_blinded medication role</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000224 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000224">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000116"/>
<obo:IAO_0000111>sub-investigator role</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a worker role authorized to make study-related decisions and carry out tasks related to the study; this role occurs during the study timeline</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>sub-investigator</obo:IAO_0000118>
<obo:IAO_0000232 xml:lang="en">CDISC definition: Sub-investigator. Any member of the clinical trial team designated and supervised by the investigator at a trial site to perform critical trial-related procedures and/or to make important trial-related decisions (e.g., associates, residents, research fellows) [ICH] See associates, residents, research fellows</obo:IAO_0000232>
<rdfs:label xml:lang="en">sub-investigator role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000227 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000227">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000572"/>
<obo:IAO_0000111 xml:lang="en">data encoding</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">storage of measurement results from an assay into a text file, such as</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a documenting process to encode an information entity into a digital document</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PlanAndPlannedProcess Branch</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">We (protocol application branch) placed this term because it kept getting bounced from data transformation and DENRIE</obo:IAO_0000232>
<rdfs:label xml:lang="en">data encoding</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000231 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000231">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000427"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100051"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">enzymatic cleavage</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Polymorphism R62W results in resistance of CD23 to enzymatic cleavage in cultured cells. Genes Immun. 2007 Apr;8(3):215-23. Epub 2007 Feb 15. PMID: 17301828</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">a material processing that digests the fraction of input material that is susceptible to that enzyme</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PlanAndPlannedProcess Branch</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">enzymatic cleavage</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000232 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000232">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000134"/>
<obo:IAO_0000111 xml:lang="en">hardware optimization objective</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Hardware_optimization is a hardware_testing_objective describing a study designed to identify the best hardware.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Jennifer Fostel</obo:IAO_0000117>
<rdfs:label xml:lang="en">hardware optimization objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000233 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000233">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_defined_material</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000121"/>
<obo:IAO_0000115 xml:lang="en">Place holder class, Utility class to gather the defined classes</obo:IAO_0000115>
<obo:IAO_0000117>Susanna Sansone</obo:IAO_0000117>
<obo:IAO_0000119>OBI Biomaterial derived</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000226"/>
<rdfs:label>obsolete_defined_material</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000234 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000234">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000116"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:allValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000066"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000059"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0500001"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:allValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>trial statistician role</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a worker role that analyzes data obtained during a trial or study; this role occurs after the trial or study is completed or terminated.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person:Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>trial statistician</obo:IAO_0000118>
<obo:IAO_0000232 xml:lang="en">CDISC definition: trial statistician. A statistician who has a combination of education/training and experience sufficient to implement the principles in the ICH E9 guidance and who is responsible for the statistical aspects of the trial. [ICH E9]</obo:IAO_0000232>
<rdfs:label xml:lang="en">trial statistician role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000235 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000235">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000071"/>
<obo:IAO_0000111 xml:lang="en">standard error</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A quantitative confidence value which is the standard deviations of the sample in a frequency distribution, obtained by dividing the standard deviation by the total number of cases in the frequency distribution.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">person:Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>group:OBI</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">see P-Value</obo:IAO_0000232>
<rdfs:label xml:lang="en">standard error</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000237 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000237">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0006955"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>antigen role</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A role of a material entity that is being recognized in whole or in part by receptors of the immune system such as antibodies or T cell receptors.</obo:IAO_0000115>
<obo:IAO_0000116>An antigen is a substance that prompts the generation of antibodies and can cause an immune response. Wikipedia http://en.wikipedia.org/wiki/Antigen. In the strict sense, immunogens are those substances that elicit a response from the immune system, whereas antigens are defined as substances that bind to specific antibodies. Not all antigens produce an immunogenic response, but all immunogens are antigens</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Role Branch</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000232>9Mar09 waiting for discussion with immunology terms</obo:IAO_0000232>
<rdfs:label xml:lang="en">antigen role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000242 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000242">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000208"/>
<obo:IAO_0000111 xml:lang="en">software testing objective</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Software_testing_objective is a hardware_optimization role describing a study designed to examine the effects of using different software or software parameters, e.g. data processing software.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Jennifer Fostel</obo:IAO_0000117>
<rdfs:label xml:lang="en">software testing objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000243 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000243">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000102"/>
<obo:IAO_0000111 xml:lang="en">sponsor role</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a responsible party role involved with any of the following activities: initiating, managing and funding a study</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>sponsor</obo:IAO_0000118>
<obo:IAO_0000232 xml:lang="en">CDISC definition: sponsor. 1. An individual, company, institution, or organization that takes responsibility for the initiation, management, and/or financing of a clinical trial. 2. A corporation or agency whose employees conduct the investigation is considered a sponsor; employees are considered investigators</obo:IAO_0000232>
<rdfs:label xml:lang="en">sponsor role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000245 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000245">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000111 xml:lang="en">organization</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PMID: 16353909.AAPS J. 2005 Sep 22;7(2):E274-80. Review. The joint food and agriculture organization of the United Nations/World Health Organization Expert Committee on Food Additives and its role in the evaluation of the safety of veterinary drug residues in foods.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An entity that can bear roles, has members, and has a set of organization rules. Members of organizations are either organizations themselves or individual people. Members can bear specific organization member roles that are determined in the organization rules. The organization rules also determine how decisions are made on behalf of the organization by the organization members.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">BP: The definition summarizes long email discussions on the OBI developer, roles, biomaterial and denrie branches. It leaves open if an organization is a material entity or a dependent continuant, as no consensus was reached on that. The current placement as material is therefore temporary, in order to move forward with development. Here is the entire email summary, on which the definition is based:
1) there are organization_member_roles (president, treasurer, branch
editor), with individual persons as bearers
2) there are organization_roles (employer, owner, vendor, patent holder)
3) an organization has a charter / rules / bylaws, which specify what roles
there are, how they should be realized, and how to modify the
charter/rules/bylaws themselves.
It is debatable what the organization itself is (some kind of dependent
continuant or an aggregate of people). This also determines who/what the
bearer of organization_roles' are. My personal favorite is still to define
organization as a kind of 'legal entity', but thinking it through leads to
all kinds of questions that are clearly outside the scope of OBI.
Interestingly enough, it does not seem to matter much where we place
organization itself, as long as we can subclass it (University, Corporation,
Government Agency, Hospital), instantiate it (Affymetrix, NCBI, NIH, ISO,
W3C, University of Oklahoma), and have it play roles.
This leads to my proposal: We define organization through the statements 1 -
3 above, but without an 'is a' statement for now. We can leave it in its
current place in the is_a hierarchy (material entity) or move it up to
'continuant'. We leave further clarifications to BFO, and close this issue
for now.</obo:IAO_0000116>
<obo:IAO_0000117>PERSON: Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Susanna Sansone</obo:IAO_0000117>
<obo:IAO_0000119>GROUP: OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">organization</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000248 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000248">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000162"/>
<obo:IAO_0000111>feed role</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Purina rat chow; cited use: Control; F = feed (rat chow); W = water; F. g. = feed-ginger concentrate. www.academicjournals.org/AJB/PDF/pdf2007/19Sep/Egwurugwu%20et%20al.pdf - Feb 29, 2008</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a role that inheres in a material entity and is realized in the use of that material entity by lab animal to provide all needed nourishment.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>feed</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">feed role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000249 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000249">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000220"/>
<obo:IAO_0000111>technical replicate role</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Aliquots of a tissue subjected to parallel assays</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">technical replicate role is realized when two portions from one evaluant are used in replicate runs of an assay</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>technical replicate</obo:IAO_0000118>
<rdfs:label xml:lang="en">technical replicate role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000250 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000250">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002743"/>
<obo:IAO_0000111 xml:lang="en">dye role</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A molecular label role which inheres in a material entity and which is realized in the process of detecting a molecular dye that imparts color to some material of interest.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>dye</obo:IAO_0000118>
<obo:IAO_0000119>A substance used to color materials www.answers.com/topic/dye 19feb09</obo:IAO_0000119>
<rdfs:label xml:lang="en">dye role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000251 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000251">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000100"/>
<obo:IAO_0000111 xml:lang="en">cluster</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Cluster of the lymphocytes population.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A data set which is a subset of data that are a similar to each other in some way.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">person:Allyson</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">person:Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>group:OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">cluster</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000252 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000252">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000198"/>
<obo:IAO_0000111>cohort role</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">In statistics and demography, a cohort is a group of subjects - most often humans from a given population - defined by experiencing an event (typically birth) in a particular time span. Wikipedia "cohort", Feb 29 2008</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a cohort role is a biological replicate role played by a group of study participants who share a common characteristic of interest to the study.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000119>WEB:http://www.sceoc.com/glossaryofterms/ # a group of individuals having a statistical factor (as age or class membership) in common in a demographic study, such as a cohort of students.</obo:IAO_0000119>
<obo:IAO_0000119>WEB:http://www.thebody.org/content/treat/art2612.html # a group of individuals in a study who share a demographic, clinical, or other statistical characteristic (eg, age, study site).</obo:IAO_0000119>
<obo:IAO_0000119>WEB:http://www.uhhospitals.org/tabid/591/Default.aspx # A cohort is a group of people with a common characteristic that is studied over a period of time as part of a scientific or medical investigation.</obo:IAO_0000119>
<rdfs:label xml:lang="en">cohort role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000253 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000253">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">artificially induced nucleic acid hybridization</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">www.ornl.gov/sci/techresources/Human_Genome/publicat/97pr/09gloss.html, http://www.accessexcellence.org/RC/VL/GG/nucleic.html, http://omrf.ouhsc.edu/~frank/HYBNOTES.html. http://en.wikipedia.org/wiki/Nucleic_acid_hybridization,http://www.pnas.org/cgi/reprint/46/8/1044.pdf</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">Is a material transformation in which strands of nucleic acids that are (somewhat) complementary form a double-stranded molecule. Has input at least two single stranded molecules of nucleic acid molecules.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PlanAndPlannedProcess Branch</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">artificially induced nucleic acid hybridization</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000257 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000257">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0666667"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001051"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">DNA extraction</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A DNA extraction is a nucleic acid extraction where the desired output material is DNA.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PlanAndPlannedProcess Branch</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">DNA extraction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000260 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000260">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000017"/>
<obo:IAO_0000111 xml:lang="en">plan</obo:IAO_0000111>
<obo:IAO_0000112>The plan of researcher X to perform an experiment according to a protocol.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A plan is a realizable entity that is the inheres in a bearer who is committed to realizing it as a planned process.</obo:IAO_0000115>
<obo:IAO_0000116>This class is included to make clear how the plan specification, the plan, and the planned process relate. OBI will however only subclass and work under the 'plan specification', and 'planned process' class, as we want to avoid to get deep into discussions of 'intend' etc.</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">AR, BP, JM, MC, PRS</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">plan</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000264 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000264">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_sample population</obo:IAO_0000111>
<obo:IAO_0000112>Patterns of benzylpiperazine/trifluoromethylphenylpiperazine party pill use and adverse effects in a population sample in New Zealand. Drug Alcohol Rev. 2008 Mar 31:1-7. PMID: 18608458</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A sample population is an object aggregate that is selected from the population, e.g. the fish in the net that were sampled from the lake, the people that responded to the call for volunteers.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>recruited population</obo:IAO_0000118>
<obo:IAO_0000119>GROUP: OBI Biomaterial Branch</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
<rdfs:label>obsolete_sample population</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000268 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000268">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000015"/>
<obo:IAO_0000111 xml:lang="en">organism feature identification objective</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Organism_feature_identification_objective is a biological_feature_identification_objective role describing a study designed to examine or characterize a biological feature monitored at the level of the organism, e.g. height, weight, stage of development, stage of life cycle.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Jennifer Fostel</obo:IAO_0000117>
<rdfs:label xml:lang="en">organism feature identification objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000269 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000269">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
<obo:IAO_0000111 xml:lang="en">number of lost events computer</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">0, 125, 787 events lost due to computer busy.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A measurement datum recording the number of measurement events lost due to overloading of the analysis chip in a flow cytometer instrument. The datum has a qualitative role</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">person:Kevin Clancy</obo:IAO_0000117>
<obo:IAO_0000119>Submitted by the Flow Cytometry community in DigitalEntity-FlowCytometry-2007-03-30.txt</obo:IAO_0000119>
<rdfs:label xml:lang="en">number of lost events computer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000272 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000272">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000104"/>
<obo:IAO_0000111 xml:lang="en">protocol</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PCR protocol, has objective specification, amplify DNA fragment of interest, and has action specification describes the amounts of experimental reagents used (e..g. buffers, dNTPS, enzyme), and the temperature and cycle time settings for running the PCR.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A plan specification which has sufficient level of detail and quantitative information to communicate it between investigation agents, so that different investigation agents will reliably be able to independently reproduce the process.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PlanAndPlannedProcess Branch</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived + wikipedia (http://en.wikipedia.org/wiki/Protocol_%28natural_sciences%29)</obo:IAO_0000119>
<obo:OBI_0001847>study protocol</obo:OBI_0001847>
<rdfs:label xml:lang="en">protocol</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000273 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000273">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000014"/>
<obo:IAO_0000111>role of regulator of consumables and medical devices</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">FDA, EMEA; http://www.fda.gov/; The International Conference of Drug Regulatory Authorities (ICDRAs) provide drug regulatory authorities of WHO Member States with a forum to meet and discuss ways to strengthen collaboration.http://www.who.int/medicines/areas/quality_safety/regulation_legislation/icdra/en/index.html</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a regulator involved with making and enforcing legislation and governmental orders relevant to the development, testing, manufacture and use of food, drugs and medical devices</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>drug regulatoy authority</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">OBI, CDISC</obo:IAO_0000119>
<rdfs:label xml:lang="en">role of regulator of consumables and medical devices</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000274 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000274">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000434"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000652"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000319"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000444"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000319"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000444"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>adding a material entity into a target</obo:IAO_0000111>
<obo:IAO_0000112>Injecting a drug into a mouse. Adding IL-2 to a cell culture. Adding NaCl into water.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">is a process with the objective to place a material entity bearing the 'material to be added role' into a material bearing the 'target of material addition role'.</obo:IAO_0000115>
<obo:IAO_0000116>Class was renamed from 'administering substance', as this is commonly used only for additions into organisms.</obo:IAO_0000116>
<obo:IAO_0000117>BP</obo:IAO_0000117>
<obo:IAO_0000119>branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">adding a material entity into a target</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000275 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000275">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002444"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_33250"/>
</owl:unionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>analyte role</obo:IAO_0000111>
<obo:IAO_0000112>Glucose in blood (measured in an assay to determine the concentration of glucose).</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A measurand role borne by a molecular entity or an atom and realized in an analyte assay which achieves the objective to measure the magnitude/concentration/amount of the analyte in the entity bearing evaluant role.</obo:IAO_0000115>
<obo:IAO_0000116>interestingly, an analyte is still an analyte even if it is not detected. for this reason it does not bear a specified input role</obo:IAO_0000116>
<obo:IAO_0000116>pH (technically the inverse log of [H+]) may be considered a quality; this remains to be tested.</obo:IAO_0000116>
<obo:IAO_0000116>qualities such as weight, color are not assayed but measured, so they do not fall into this category.</obo:IAO_0000116>
<obo:IAO_0000117>GROUP: Role Branch</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000232>Feb 10, 2009. changes after discussion at OBI Consortium Workshop Feb 2-6, 2009. accepted as core term.</obo:IAO_0000232>
<rdfs:label xml:lang="en">analyte role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000278 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000278">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000063"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>disease stage</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Stage II breast cancer, The timepoint of recovery from a disease</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a part of an occurrence of a disease process which is associated with position in the normal progression of the disease</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Bjoern peters</obo:IAO_0000117>
<rdfs:label xml:lang="en">disease stage</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000281 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000281">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000429"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000422"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000426"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000429"/>
<obo:IAO_0000111>intraperitoneal injection</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">is the injection of a material entity (bearing the administered substance role) into the peritoneum (bearing the target role) of an organism using a syringe</obo:IAO_0000115>
<obo:IAO_0000117>BP</obo:IAO_0000117>
<rdfs:label>intraperitoneal injection</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000286 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000286">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600034"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">precipitate</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Physicochemical properties and antibacterial activity of the precipitate of vancomycin and ceftazidime: implications in the management of endophthalmitis. Retina. 2008 Feb;28(2):320-5. PMID: 18301038</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a precipitate is a material entity which is output of a precipitation process</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">precipited material</obo:IAO_0000118>
<obo:IAO_0000119>GROUP: OBI Biomaterial Branch</obo:IAO_0000119>
<rdfs:label xml:lang="en">precipitate</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000288 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000288">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>protein-protein interaction detection assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An assay that determines interactions between proteins, such as protein-protein binding.</obo:IAO_0000115>
<rdfs:label>protein-protein interaction detection assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000291 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000291">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001146"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/SO_0000235"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>transcription factor binding site assay</obo:IAO_0000111>
<obo:IAO_0000112>Transcription factor binding site identification in yeast: a comparison of high-density oligonucleotide and PCR-based microarray platforms.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay tthat determines DNA regions specifically recognized by proteins that function as transcription factors</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>TF binding</obo:IAO_0000118>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000233>https://sourceforge.net/p/obi/obi-terms/767/</obo:IAO_0000233>
<rdfs:label>transcription factor binding site assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000296 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000296">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_enrollment</obo:IAO_0000111>
<obo:IAO_0000112>Enrollment of patients in a study. Short-term outcome of neuropsychiatric events in systemic lupus erythematosus upon enrollment into an international inception cohort study. Arthritis Rheum. 2008 May 15;59(5):721-9. PMID: 18438902</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">enrollment is a process of identifying a set of objects for further use in an investigation based on a set of criteria or rules</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
<rdfs:label>obsolete_enrollment</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000310 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000310">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000001"/>
<obo:IAO_0000111 xml:lang="en">adverse event trigger</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">revisit?</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON:Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">adverse event trigger</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000318 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000318">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0302732"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0302905"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">eluate</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Raman spectroscopic detection of haemoproteins in the eluate from high-performance liquid chromatography. J Chromatogr. 1983 Jan 7;254:285-8. PMID: 6298263</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a eluate is a material entity which results from an elution, e.g. from a chromatography column. it has as part a material entity with role mobile phase</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">need to add restriction to indicate: has_part some (material entity has_role mobile phase)
need to add mobile phase as role</obo:IAO_0000116>
<obo:IAO_0000117>PERSON: Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">eluted material</obo:IAO_0000118>
<obo:IAO_0000119>OBI Bionaterial</obo:IAO_0000119>
<rdfs:label xml:lang="en">eluate</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000319 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000319">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<obo:IAO_0000111>material to be added role</obo:IAO_0000111>
<obo:IAO_0000112>drug added to a buffer contained in a tube; substance injected into an animal;</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A role of a material entity that is realized in an "adding a material entity into a target" process where the bearer of the role is added into another material entity (the target).</obo:IAO_0000115>
<obo:IAO_0000117>Role Branch</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000232>9 March 09 from discussion with PA branch</obo:IAO_0000232>
<rdfs:label xml:lang="en">material to be added role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000323 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000323">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_peritoneum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000002"/>
<obo:IAO_0000115 xml:lang="en">is the serous membrane that forms the lining of the abdominal cavity</obo:IAO_0000115>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<rdfs:label>obsolete_peritoneum</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000338 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000338">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001909"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>interpreting data</obo:IAO_0000111>
<obo:IAO_0000112>Concluding that a gene is upregulated in a tissue sample based on the band intensity in a western blot. Concluding that a patient has a infection based on measurement of an elevated body temperature and reported headache. Concluding that there were problems in an investigation because data from PCR and microarray are conflicting. Concluding that 'defects in gene XYZ cause cancer due to improper DNA repair' based on data from experiments in that study that gene XYZ is involved in DNA repair, and the conclusion of a previous study that cancer patients have an increased number of mutations in this gene.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A planned process in which data gathered in an investigation is evaluated in the context of existing knowledge with the objective to generate more general conclusions or to conclude that the data does not allow one to draw general conclusion</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000119>Bjoern Peters</obo:IAO_0000119>
<rdfs:label xml:lang="en">drawing a conclusion based on data</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000339 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000339">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000015"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000104"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>planning</obo:IAO_0000111>
<obo:IAO_0000112>The process of a scientist thinking about and deciding what reagents to use as part of a protocol for an experiment. Note that the scientist could be human or a "robot scientist" executing software.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">a process of creating or modifying a plan specification</obo:IAO_0000115>
<obo:IAO_0000116>7/18/2011 BP: planning used to itself be a planned process. Barry Smith pointed out that this would lead to an infinite regression, as there would have to be a plan to conduct a planning process, which in itself would be the result of planning etc. Therefore, the restrictions on 'planning' were loosened to allow for informal processes that result in an 'ad hoc plan '. This required changing from 'has_specified_output some plan specifiction' to 'has_participant some plan specification'.</obo:IAO_0000116>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>Bjoern Peters</obo:IAO_0000119>
<obo:IAO_0000119>Plans and Planned Processes Branch</obo:IAO_0000119>
<rdfs:label xml:lang="en">planning</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000340 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000340">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_documenting</obo:IAO_0000111>
<obo:IAO_0000112>Recording the current temperature in a laboratory notebook. Writing a journal article. Updating a patient record in a database.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>wikipedia http://en.wikipedia.org/wiki/Documenting</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000572"/>
<rdfs:label>obsolete_documenting</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000341 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000341">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100066"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000684"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400168"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">histological sample preparation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">histological sample preparation is the preparation of an input tissue via slicing and labeling to make tissue microstructure of interest visible in a future histology assay</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON:Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">histological sample preparation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000343 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000343">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000338"/>
<obo:IAO_0000111>inductive reasoning</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Based on the observation that all lung cancer patients treated with aspirin in our clinical trial survived longer than the control group, we conclude by inductive reasining that aspirin has a therapeutic effect on lung cancer.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000115 xml:lang="en">a interpreting data that is used to ascribe properties or relations to types based on an observation instance (i.e., on a number of observations or experiences); or to formulate laws based on limited observations of recurring phenomenal patterns.</obo:IAO_0000115>
<obo:IAO_0000116>BP: 10/22/122: After changing the parent class to drawing a conclusion *based on data* it is no longer clear that this class is needed; minimally it needs a better definition to distinguish it.
Proposal is to obsolete.</obo:IAO_0000116>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>wikipedia: http://en.wikipedia.org/wiki/Inductive_reasoning</obo:IAO_0000119>
<rdfs:label xml:lang="en">inductive reasoning</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000345 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000345">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000932"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000372"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>mass analyzer</obo:IAO_0000111>
<obo:IAO_0000112>The mass analyzer of the Voyager-DE(tm) STR Biospectrometry Workstation</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A Mass analyzer is a device that separates ions according to their mass-to-charge ratio. All mass spectrometers are based on dynamics of charged particles in electric and magnetic fields in vacuum where the two laws of Lorentz force law and Newton's second law of motion apply.</obo:IAO_0000115>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Mass_spectrometry#Mass_analyzer</obo:IAO_0000119>
<rdfs:label>mass analyzer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000355 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000355">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000066"/>
<obo:IAO_0000111 xml:lang="en">hypothesis driven investigation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">is an investigation with the goal to test one or more hypothesis</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PlanAndPlannedProcess Branch</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">hypothesis driven investigation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000356 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000356">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000066"/>
<obo:IAO_0000111 xml:lang="en">hypothesis generating investigation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">is an investigation in which data is generated and analyzed with the purpose of generating new hypothesis</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PlanAndPlannedProcess Branch</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">hypothesis generating investigation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000361 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000361">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000385"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>ion source</obo:IAO_0000111>
<obo:IAO_0000112>The ion source of a Voyager-DE??? STR Biospectrometry Workstation</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An ion source is a device that is part of a mass spectrometer that ionizes the material under analysis. The ions are then transported by magnetic or electric fields to the mass analyzer. Techniques for ionization have been key to determining what types of samples can be analyzed by mass spectrometry. Electron ionization and chemical ionization are used for gases and vapors. In chemical ionization sources, the material is ionized by chemical ion-molecule reactions during collisions in the source. Two techniques often used with liquid and solid biological samples include electrospray ionization (due to John Fenn PMID 2675315.) and matrix-assisted laser desorption/ionization (MALDI, due to M. Karas and F. Hillenkamp (Measuring Mass: From Positive Rays to Proteins by Michael A. Grayson (Editor) (ISBN 0-941901-31-9))).</obo:IAO_0000115>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Mass_spectrometry#Ion_source</obo:IAO_0000119>
<rdfs:label>ion source</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000364 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000364">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>ion detector</obo:IAO_0000111>
<obo:IAO_0000112>The ion detector of the Voyager-DE(tm) STR Biospectrometry Workstation</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An ion detector is a device that measures and records the charge induced or current produced when an ion passes by or hits a surface. Example: In a scanning instrument the signal produced in the detector during the course of the scan versus where the instrument is in the scan (at what m/Q) will produce a mass spectrum, a record of ions as a function of m/Q.</obo:IAO_0000115>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Mass_spectrometry#Detector</obo:IAO_0000119>
<rdfs:label>ion detector</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000366 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000366">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100051"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>metabolite profiling assay</obo:IAO_0000111>
<obo:IAO_0000112>Metabolite profiling of human colon carcinoma - deregulation of TCA cycle and amino acid turnover. Mol Cancer. 2008 Sep 18;7(1):72. PMID: 18799019</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that detects and identifies chemical entities resulting from biochemical and cellular metabolism</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>metabolite assay</obo:IAO_0000118>
<obo:IAO_0000118>metabolomic assay</obo:IAO_0000118>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>metabolite profiling assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000367 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000367">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000374"/>
<obo:IAO_0000111 xml:lang="en">light emission function</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A light emission function is an excitation function to excite a material to a specific excitation state that it emits light.</obo:IAO_0000115>
<obo:IAO_0000117>Bill Bug</obo:IAO_0000117>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<rdfs:label xml:lang="en">light emission function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000368 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000368">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
<obo:IAO_0000111 xml:lang="en">record function</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A record function is a function that registers or collects information in a particular format on a particular recording medium. For example on paper or a digital representation</obo:IAO_0000115>
<obo:IAO_0000117>Bill Bug</obo:IAO_0000117>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<rdfs:label xml:lang="en">record function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000369 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000369">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
<obo:IAO_0000111 xml:lang="en">magnify function</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A magnify function is a function to increase the size of a transmitted object image through the precise arrangement of energy diffraction elements along an imaging path.</obo:IAO_0000115>
<obo:IAO_0000117>Bill Bug</obo:IAO_0000117>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<rdfs:label xml:lang="en">magnify function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000370 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000370">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
<obo:IAO_0000111 xml:lang="en">contain function</obo:IAO_0000111>
<obo:IAO_0000112>A syringe, a beaker</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A contain function is a function to constrain a material entities location in space</obo:IAO_0000115>
<obo:IAO_0000117>Bill Bug</obo:IAO_0000117>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<rdfs:label xml:lang="en">contain function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000371 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000371">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
<obo:IAO_0000111 xml:lang="en">heat function</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A heat function is a function that increases the internal kinetic energy of a material</obo:IAO_0000115>
<obo:IAO_0000117>Bill Bug</obo:IAO_0000117>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<rdfs:label xml:lang="en">heat function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000372 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000372">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
<obo:IAO_0000111 xml:lang="en">material separation function</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A material separation function is a function that increases the resolution between two or more material entities. The to distinction between the entities is usually based on some associated physical quality.</obo:IAO_0000115>
<obo:IAO_0000117>Bill Bug</obo:IAO_0000117>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<rdfs:label xml:lang="en">material separation function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000373 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000373">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000385"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>ionize process</obo:IAO_0000111>
<obo:IAO_0000112>Electrospray ionization in mass spectrometry</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a physical process of converting an atom or molecule into an ion by adding or removing charged particles such as electrons or other ions. This excludes chemical processes of dissociation.</obo:IAO_0000115>
<obo:IAO_0000116>2009-11-10. Tracker: http://en.wikipedia.org/wiki/Ionize</obo:IAO_0000116>
<obo:IAO_0000117>Person:Bjoern Peters</obo:IAO_0000117>
<rdfs:label xml:lang="en">ionize process</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000374 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000374">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
<obo:IAO_0000111 xml:lang="en">excitation function</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A excitation function is a function to inject energy by bombarding a material with energetic particles (e.g., photons) thereby imbuing internal material components such as electrons with additional energy. These internal, 'excited' particles may lead to the rupturing of covalent chemical bonds or may quickly relax back to there unexcited state with an exponential time course thereby locally emitting energy in the form of photons.</obo:IAO_0000115>
<obo:IAO_0000117>Bill Bug</obo:IAO_0000117>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<rdfs:label xml:lang="en">excitation function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000375 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000375">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
<obo:IAO_0000111 xml:lang="en">freeze function</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A freeze function is a function to decrease the internal kinetic energy of a material below the freezing point of that type of material.</obo:IAO_0000115>
<obo:IAO_0000117>Bill Bug</obo:IAO_0000117>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<rdfs:label xml:lang="en">freeze function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000376 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000376">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
<obo:IAO_0000111 xml:lang="en">synthesizing function</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A synthesizing function is a function to assemble new output materials from distinct input materials. The output materials typically consist of chemically distinct monomeric objects or object aggregate polymers.</obo:IAO_0000115>
<obo:IAO_0000117>Bill Bug</obo:IAO_0000117>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<rdfs:label xml:lang="en">synthesizing function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000377 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000377">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
<obo:IAO_0000111 xml:lang="en">perturb function</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A perturb function is a function that disrupts the normal function of a system induced through either internal or external means. External means of perturbation include: (1) displacement fields in the physical sense - e.g., temperature change, osmotic shock, pressure change; (2) application of small molecules such as drugs or toxins to perturb the function of specific pathways or application of surfactants to perturb the normal function of plasma membrane. Internal means of perturbation include: (1) manipulation of gene function via gene knockout or transcript knockdown via RNAi; (2) directed genetic mutation leading to minimal aa alterations that interfere with peptide function.</obo:IAO_0000115>
<obo:IAO_0000117>Bill Bug</obo:IAO_0000117>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">http://en.wikipedia.org/wiki/Perturbation_biology</obo:IAO_0000119>
<rdfs:label xml:lang="en">perturb function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000378 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000378">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000372"/>
<obo:IAO_0000111 xml:lang="en">filter function</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A filter function is a function to prevent the flow of certain entities based on a quality or qualities of the entity while allowing entities which have different qualities to pass through</obo:IAO_0000115>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<rdfs:label xml:lang="en">filter function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000379 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000379">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
<obo:IAO_0000111 xml:lang="en">mechanical function</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A mechanical function is a function that is realised via mechanical work (through an certain amount of energy transferred by some force).</obo:IAO_0000115>
<obo:IAO_0000117>Bill Bug</obo:IAO_0000117>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">http://en.wikipedia.org/wiki/Mechanical_work</obo:IAO_0000119>
<rdfs:label xml:lang="en">mechanical function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000380 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000380">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000378"/>
<obo:IAO_0000111 xml:lang="en">gas filter function</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A gas filter function is a filter function which prevents the flow of solid objects, defined by specific qualities, in a gas-solid mixture</obo:IAO_0000115>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<rdfs:label xml:lang="en">gas filter function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000381 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000381">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000378"/>
<obo:IAO_0000111 xml:lang="en">liquid filter function</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A liquid filter function is a filter function which prevents the flow of solid objects, defined by specific qualities, in a liquid-solid mixture</obo:IAO_0000115>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<rdfs:label xml:lang="en">liquid filter function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000383 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000383">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
<obo:IAO_0000111 xml:lang="en">transfer function</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A transfer function is a function to displace a material from one location to another.</obo:IAO_0000115>
<obo:IAO_0000117>Bill Bug</obo:IAO_0000117>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<rdfs:label xml:lang="en">transfer function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000384 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000384">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000391"/>
<obo:IAO_0000111 xml:lang="en">electricity supply function</obo:IAO_0000111>
<obo:IAO_0000112>the function of supplying current during a neuroscience experiment.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An electricity supply function is an energy supply function to transfer electricity from one source to another, typically a consumer of the electricity or as a stimulus during a neuroscience experiment.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">power supply</obo:IAO_0000118>
<rdfs:label xml:lang="en">electricity supply function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000385 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000385">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
<obo:IAO_0000111 xml:lang="en">ionization function</obo:IAO_0000111>
<obo:IAO_0000112>The ion source in amass spectrometer</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An ionization function is a function to physically convert an atom or molecule into an ion by adding or removing charged particles such as electrons or other ions.</obo:IAO_0000115>
<obo:IAO_0000117>Bill Bug</obo:IAO_0000117>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">http://en.wikipedia.org/wiki/Ionization</obo:IAO_0000119>
<rdfs:label xml:lang="en">ionization function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000387 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000387">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
<obo:IAO_0000111 xml:lang="en">cool function</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A cool function is a function to decrease the internal kinetic energy of a material below the initial kinetic energy of that type of material.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<rdfs:label xml:lang="en">cool function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000388 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000388">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
<obo:IAO_0000111 xml:lang="en">connection function</obo:IAO_0000111>
<obo:IAO_0000112>An electricity cable</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A connection function is a function to couple two or more flow channels so that material or signals can be transported from one set of channels to another.</obo:IAO_0000115>
<obo:IAO_0000117>Bill Bug</obo:IAO_0000117>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<rdfs:label xml:lang="en">connection function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000389 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000389">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002089"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000370"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000383"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000401"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>isoelectric focusing device</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An isoelectric focusing device is a device in which isoelectric focusing can be performed. An isoelectric focussing device had the function to contain and control the contained environment and transfer electrical energy from a power supply to a separation medium and the charged material to be separated.</obo:IAO_0000115>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000118>isoelectric focusing unit</obo:IAO_0000118>
<obo:IAO_0000119>sep:00097</obo:IAO_0000119>
<rdfs:label>isoelectric focusing device</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000390 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000390">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002089"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000370"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000401"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>thermostatic circulator</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A thermostatic circulator is a device which cools or heats a circulating liquid. It has the function to contain control the contained environment and transfer energy from or to the circulating liquid</obo:IAO_0000115>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000119>sep:00098</obo:IAO_0000119>
<rdfs:label>thermostatic circulator</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000391 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000391">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
<obo:IAO_0000111 xml:lang="en">energy supply function</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An energy supply function is a function to supply or transfer energy from an energy source to a consumer of the energy</obo:IAO_0000115>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<rdfs:label xml:lang="en">energy supply function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000392 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000392">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000455"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">information processor function</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An information processor function is a function that converts information from one form to another, by a lossless process or an extraction process.</obo:IAO_0000115>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">data processor function</obo:IAO_0000118>
<rdfs:label xml:lang="en">information processor function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000393 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000393">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000392"/>
<obo:IAO_0000111 xml:lang="en">signal conversion function</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A signal conversion function is an information processor function which transforms a signal into another type of signal. For example an analog-to-digital_converter, Ac/Ac converter, a synapse converts electrical action potentials into an intermediate chemical signal. The post synapse converts it back into an electric one passed on to the axon.</obo:IAO_0000115>
<obo:IAO_0000117>Bill Bug</obo:IAO_0000117>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000118>transduction function</obo:IAO_0000118>
<rdfs:label xml:lang="en">signal conversion function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000394 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000394">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000383"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>blot module</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A blot module is a device which has the function to conatin and facilitate the material transfer process blotting to be realised</obo:IAO_0000115>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000119>sep:00092</obo:IAO_0000119>
<rdfs:label>blot module</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000395 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000395">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000393"/>
<obo:IAO_0000111 xml:lang="en">signal amplification function</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A signal amplification function is a signal conversion function to inject energy into an input signal so as to produce an output signal with increased differential magnitude while also seeking to minimize increases in the signal to noise ratio. For example, to produce a 0.1 KW output signal from a 1 mW RMS input signal.</obo:IAO_0000115>
<obo:IAO_0000117>Bill Bug</obo:IAO_0000117>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<rdfs:label xml:lang="en">signal amplification function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000397 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000397">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000398"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001007"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">image acquisition function</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An image acquisition function is a function to acquire an image of a material</obo:IAO_0000115>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<rdfs:label xml:lang="en">image acquisition function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000398 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000398">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000968"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000397"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
<obo:IAO_0000111>image acquisition device</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An image creation device is a device which captures a digitized image of an object</obo:IAO_0000115>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000118>image acquisition device</obo:IAO_0000118>
<obo:IAO_0000119>sep:00096</obo:IAO_0000119>
<rdfs:label>image creation device</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000399 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000399">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
<obo:IAO_0000111>solid support function</obo:IAO_0000111>
<obo:IAO_0000112>Taped, glued, pinned, dried or molecularly bonded to a solid support</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A solid support function is a function of a device on which an entity is kept in a defined position and prevented in its movement</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<rdfs:label xml:lang="en">solid support function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000400 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000400">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000392"/>
<obo:IAO_0000111 xml:lang="en">display function</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A display function is a function to present information by translating that information through some lookup process into visual form.</obo:IAO_0000115>
<obo:IAO_0000117>Bill Bug</obo:IAO_0000117>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<rdfs:label xml:lang="en">display function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000401 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000401">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
<obo:IAO_0000111 xml:lang="en">environment control function</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An environmental control function is a function that regulates a contained environment within specified parameter ranges. For example the control of light exposure, humidity and temperature.</obo:IAO_0000115>
<obo:IAO_0000117>Bill Bug</obo:IAO_0000117>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<rdfs:label xml:lang="en">environment control function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000403 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000403">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000372"/>
<obo:IAO_0000111 xml:lang="en">sort function</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A sort function is a function to distinguish material components based on some associated physical quality or entity and to partition the separate components into distinct fractions according to a defined order.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<rdfs:label xml:lang="en">sort function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000404 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000404">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002089"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000370"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000401"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>gel dryer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A gel dryer is a device which has the function to contain and to control the contained environment to facilitate the drying of gels</obo:IAO_0000115>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000119>sep:00094</obo:IAO_0000119>
<rdfs:label>gel dryer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000405 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000405">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000857"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000415"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>primer role</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a complementary nucleotide probe role which inheres in nucleic acid molecular entity and is realized by the use of the entity bearing the role to initiate chain elongation.</obo:IAO_0000115>
<obo:IAO_0000119>(cell and molecular biology) A short strand of RNA that is synthesized along single-stranded DNA during replication, initiating DNA polymerase-catalyzed synthesis of the complementary strand. http://www.answers.com/topic/rna-primer</obo:IAO_0000119>
<rdfs:label xml:lang="en">primer role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000406 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000406">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_4705"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000415"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_4705"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000809"/>
<obo:IAO_0000111 xml:lang="en">PCR product</obo:IAO_0000111>
<obo:IAO_0000112>PCR products are the results of amplifcation process. Detection of a PCR products is used to detect DNA and RNA.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">is double stranded DNA that is the specified output of a polymerase chain reaction</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">We are using PCR and not the written out words, as this is the most common used.</obo:IAO_0000116>
<obo:IAO_0000117>GROUP: OBI BIomaterial Branch</obo:IAO_0000117>
<obo:IAO_0000119>GROUP: OBI BIomaterial Branch</obo:IAO_0000119>
<rdfs:label xml:lang="en">PCR product</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000407 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000407">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0666666"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10239"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>viral RNA extraction</obo:IAO_0000111>
<obo:IAO_0000112>The AccuPrepTM Viral RNA Extraction Kit is designed for the rapid and convenient extraction of viral RNA from cell-free samples as serum, plasma, CSF, urine, etc - http://www.biokits.com/moreinfos.html?id=2703</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">The extraction of RNA from an input material that specifically isolates viral RNA</obo:IAO_0000115>
<obo:IAO_0000117>Person:Bjoern Peters</obo:IAO_0000117>
<rdfs:label xml:lang="en">viral RNA extraction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000409 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000409">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000025"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33696"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000415"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>nucleic acid template role</obo:IAO_0000111>
<obo:IAO_0000112>a model or standard for making comparisons; wordnet.princeton.edu/perl/webwn 19 feb 2009</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a reference substance role which inheres in nucleic acid material entity and is realized in the process of using the nucleic acid bearing the template role as a reference during synthesis of a reverse copy.</obo:IAO_0000115>
<rdfs:label xml:lang="en">nucleic acid template role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000410 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000410">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000430"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600064"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000430"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000731"/>
<obo:IAO_0000111 xml:lang="en">recombinant plasmid</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a plasmid in which extraneous DNA has been inserted.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Kevin Clancy</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000119>GROUP: OBI Biomaterial Branch</obo:IAO_0000119>
<rdfs:label xml:lang="en">recombinant plasmid</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000411 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000411">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000319"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33696"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600064"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>cloning vector role</obo:IAO_0000111>
<obo:IAO_0000112>pBluescript plays the role of a cloning vector</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A material to be added role played by a small, self-replicating DNA or RNA molecule - usually a plasmid or chromosome - and realized in a process whereby foreign DNA or RNA is inserted into the vector during the process of cloning.</obo:IAO_0000115>
<obo:IAO_0000116>JZ: related tracker: https://sourceforge.net/p/obi/obi-terms/102/</obo:IAO_0000116>
<obo:IAO_0000117>PERSON: Helen Parkinson</obo:IAO_0000117>
<rdfs:label xml:lang="en">cloning vector role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000413 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000413">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100060"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100060"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>cell cycle synchronization</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Elimination of serum from the culture medium for about 24 hours results in the accumulation of cells at G1 phase. This effect of nutritional deprivation can be restored by their addition by which time the cell synchrony occurs.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a process with the objective to obtain a cell culture in which all cells are in the same stage of the cell cycle</obo:IAO_0000115>
<obo:IAO_0000117>OBI PA</obo:IAO_0000117>
<obo:IAO_0000119>Bjoern Peters and Nicole Washington</obo:IAO_0000119>
<rdfs:label xml:lang="en">cell cycle synchronization</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000415 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000415">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600058"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000376"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0042575"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16991"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000406"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>polymerase chain reaction</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Opisthorchis viverrini: Detection by polymerase chain reaction (PCR) in human stool samples. Exp Parasitol. 2008 Sep 9. PMID: 18805413</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">PCR is the process in which a DNA polymerase is used to amplify a piece of DNA by in vitro enzymatic replication. As PCR progresses, the DNA thus generated is itself used as a template for replication. This sets in motion a chain reaction in which the DNA template is exponentially amplified.</obo:IAO_0000115>
<obo:IAO_0000117>OBI Plan</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">PCR</obo:IAO_0000118>
<obo:IAO_0000119>adapted from wikipedai</obo:IAO_0000119>
<rdfs:label xml:lang="en">polymerase chain reaction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000416 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000416">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<obo:IAO_0000111>cloning insert role</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000121"/>
<obo:IAO_0000115 xml:lang="en">cloning insert role is a role which inheres in DNA or RNA and is realized by the process of being inserted into a cloning vector in a cloning process.</obo:IAO_0000115>
<obo:IAO_0000116>Feb 20, 2009. from Wikipedia: cloning of any DNA fragment essentially involves four steps: DNA fragmentation with restriction endonucleases, ligation of DNA fragments to a vector, transfection, and screening/selection. There are multiple processes involved, it is not just "cloning process"</obo:IAO_0000116>
<obo:IAO_0000117>GROUP: Role branch</obo:IAO_0000117>
<obo:IAO_0000119>OBII and Wikipedia</obo:IAO_0000119>
<rdfs:label xml:lang="en">cloning insert role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000418 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000418">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100020"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100017"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100017"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17234"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17234"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>measuring glucose concentration in blood serum assay</obo:IAO_0000111>
<obo:IAO_0000112>Measuring glucose concentration in blood from a mouse. See Figure 2 of the 2016 OBI paper, PMID: 27128319.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An assay that determines the concentration of glucose molecules in a blood serum sample</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>measuring glucose concentration in blood serum assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000419 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000419">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000427"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0003964"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000427"/>
<obo:IAO_0000111 xml:lang="en">reverse transcriptase</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">enzyme and has_function some GO:0003964 (RNA-directed DNA polymerase
activity)</obo:IAO_0000115>
<obo:IAO_0000117>person:Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000119>group:OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">reverse transcriptase</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000420 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000420">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_trypsinized material</obo:IAO_0000111>
<obo:IAO_0000112>A trypsinized suspension of cells</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000002"/>
<obo:IAO_0000115 xml:lang="en">A material entity that has undergone a process of digestion with trypsin</obo:IAO_0000115>
<obo:IAO_0000117>Person:Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_trypsinized material</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000422 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000422">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000383"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>syringe</obo:IAO_0000111>
<obo:IAO_0000112>Accuracy of oral liquid measuring devices: comparison of dosing cup and oral dosing syringe.Ann Pharmacother. 2008 Jan;42(1):46-52. Epub 2007 Dec 4. PMID: 18056832</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A processed material which is used to introduce or draw fluids from a material entity. A syringe is made of a piston and body. the movement of the piston in the body determines the amount/volume of fluid to inject or draw</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>OBI Instrument adapted from Wikipedia</obo:IAO_0000119>
<rdfs:label>syringe</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000423 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000423">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0302884"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">extract</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Up-regulation of inflammatory signalings by areca nut extract and role of cyclooxygenase-2 -1195G>a polymorphism reveal risk of oral cancer. Cancer Res. 2008 Oct 15;68(20):8489-98. PMID: 18922923</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">an extract is a material entity which results from an extraction process</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">extracted material</obo:IAO_0000118>
<obo:IAO_0000119>GROUP: OBI Biomatrial Branch</obo:IAO_0000119>
<rdfs:label xml:lang="en">extract</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000424 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000424">
<owl:equivalentClass>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33697"/>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33697"/>
</owl:Restriction>
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</owl:Class>
</owl:someValuesFrom>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0010467"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001331"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>transcription profiling assay</obo:IAO_0000111>
<obo:IAO_0000112>Whole genome transcription profiling of Anaplasma phagocytophilum in human and tick host cells by tiling array analysis. BMC Genomics. 2008 Jul 31;9:364. PMID: 18671858</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that determines gene expression and transcription activity using ribonucleic acids collected from a material entity.</obo:IAO_0000115>
<obo:IAO_0000116>This term should encompass transcription and post-transcription, but before translation into protein. So 'gene expression' itself is too broad, and we use 'transcription profiling identification objective' to constrain the scope of this term.</obo:IAO_0000116>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>gene expression profiling</obo:IAO_0000118>
<obo:IAO_0000118>transcription profiling</obo:IAO_0000118>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>transcription profiling assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000425 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000425">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200166"/>
<obo:IAO_0000111 xml:lang="en">averaging objective</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">A mean calculation which has averaging objective is a descriptive statistics calculation in which the mean is calculated by taking the sum of all of the observations in a data set divided by the total number of observations. It gives a measure of the 'center of gravity' for the data set. It is also known as the first moment.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An averaging objective is a data transformation objective where the aim is to perform mean calculations on the input of the data transformation.</obo:IAO_0000115>
<obo:IAO_0000117>Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Elisabetta Manduchi</obo:IAO_0000119>
<rdfs:label xml:lang="en">averaging objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000426 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000426">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000319"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000422"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000274"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000434"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>injection</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Multiple Small-Dose Injections Can Reduce the Passage of Sclerosant Foam into Deep Veins During Foam Sclerotherapy for Varicose Veins. Eur J Vasc Endovasc Surg. 2008 Oct 13. PMID: 18922712</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">injection is process which aims at introducing a compound or a mixture into a material entity (either biological entity or instrument) by relying on devices such as syringe or injector connection, attached or forced into a vascular system (veins of an organism or tubes of a machine) or in a tissue.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>OBI Biomaterial</obo:IAO_0000119>
<rdfs:label xml:lang="en">injection</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000427 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000427">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_33697"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0032991"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/PR_000000001"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33697"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0032991"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
</owl:Restriction>
</owl:unionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0003824"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000111 xml:lang="en">enzyme</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">(protein or rna) or has_part (protein or rna) and
has_function some GO:0003824 (catalytic activity)</obo:IAO_0000115>
<obo:IAO_0000116>MC: known issue: enzyme doesn't classify under material entity for now as it isn't stated that anything
that has_part some material entity is a material entity. If we add as equivalent classes to material entity has_part some material entity and part_of some material entity (each one in his own necessary and sufficient block) Pellet in P3 doesn't classify any more.</obo:IAO_0000116>
<obo:IAO_0000117>person: Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">enzyme</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000429 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000429">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0600007"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000319"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002358"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600007"/>
<obo:IAO_0000111>intraperitoneal administration</obo:IAO_0000111>
<obo:IAO_0000112>Rats were injected intraperitoneally with either rrIL-6 (250 ng/0.5 ml) or equal-volume sterile saline twice within an interval of 24 h</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">The administration of a substance into the peritoneum of an organism</obo:IAO_0000115>
<obo:IAO_0000117>Person:Bjoern Peters</obo:IAO_0000117>
<rdfs:label>intraperitoneal administration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000430 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000430">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_4705"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0010467"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000086"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/SO_0000988"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_4705"/>
<obo:IAO_0000111 xml:lang="en">plasmid</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">plasmid = DNA and has_quality circular and has_function
(is_realized_as some gene expression) GO:0010467</obo:IAO_0000115>
<obo:IAO_0000117>person:Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000119>group:OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">plasmid</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000431 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000431">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000319"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000422"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000444"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100066"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000426"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000434"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>injection into organ section</obo:IAO_0000111>
<obo:IAO_0000112>Staining a specimen of human lung tissue with hematoxylin and eosin in order as a preparative step in histology</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A process in which an input substance is injected into a organ section.</obo:IAO_0000115>
<obo:IAO_0000117>Person:Bjoern Peters</obo:IAO_0000117>
<rdfs:label xml:lang="en">injection into organ section</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000432 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000432">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_28619"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0302890"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">polyacrylamide gel</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Assessing CMT cell line stability by two dimensional polyacrylamide gel electrophoresis and mass spectrometry based proteome analysis. J Proteomics. 2008 Jul 21;71(2):160-7. PMID: 18617143</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a material entity resulting from the polymerization of acrylamide with TEMED in some buffer solution</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>GROUP: OBI Biomaterial Branch</obo:IAO_0000119>
<rdfs:label xml:lang="en">polyacrylamide gel</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000433 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000433">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001051"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001051"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000113"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>DNA sequence feature detection assay</obo:IAO_0000111>
<obo:IAO_0000112>genotyping using an Affymetrix chip</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An assay with the objective to determine a sequence feature of DNA</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>DNA sequence feature detection assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000434 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000434">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000686"/>
<obo:IAO_0000111>adding material objective</obo:IAO_0000111>
<obo:IAO_0000112>creating a mouse infected with LCM virus</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">is the specification of an objective to add a material into a target material. The adding is asymmetric in the sense that the target material largely retains its identity</obo:IAO_0000115>
<obo:IAO_0000117>BP</obo:IAO_0000117>
<rdfs:label xml:lang="en">adding material objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000435 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000435">
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001051"/>
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</owl:intersectionOf>
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</owl:someValuesFrom>
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<owl:someValuesFrom>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
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</owl:someValuesFrom>
</owl:Restriction>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
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<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100051"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16991"/>
</owl:Restriction>
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</owl:someValuesFrom>
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<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001305"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000113"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>genotyping assay</obo:IAO_0000111>
<obo:IAO_0000112>High-throughput genotyping of oncogenic human papilloma viruses with MALDI-TOF mass spectrometry. Clin Chem. 2008 Jan;54(1):86-92. Epub 2007 Nov 2.PMID: 17981923</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay which generates data about a genotype from a specimen of genomic DNA. A variety of techniques and instruments can be used to produce information about sequence variation at particular genomic positions.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>SNP analysis</obo:IAO_0000118>
<obo:IAO_0000118>genotype profiling</obo:IAO_0000118>
<obo:IAO_0000119>OBI Biomaterial</obo:IAO_0000119>
<rdfs:label>genotyping assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000436 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000436">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000383"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>needle</obo:IAO_0000111>
<obo:IAO_0000112>Ovarian carcinoma presenting with axillary lymph node metastasis: A case diagnosed by fine-needle aspiration and brief review of the literature. Diagn Cytopathol. 2008 Oct 16. PMID: 18925569</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A needle is a sharp, hollow device used to penetrate tissue or soft material. When attached to a syringe. it allows delivery of a specific volume of liquid or gaseous mixture.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>OBI Instrument</obo:IAO_0000119>
<rdfs:label>needle</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000437 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000437">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000441"/>
<obo:IAO_0000111>analyte measurement objective</obo:IAO_0000111>
<obo:IAO_0000112>The objective to measure the concentration of glucose in a blood sample</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">an assay objective to determine the presence or concentration of an analyte in the evaluant</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>PPPB branch</obo:IAO_0000119>
<rdfs:label xml:lang="en">analyte measurement objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000438 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000438">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001051"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000113"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>DNA sequence variation detection assay</obo:IAO_0000111>
<obo:IAO_0000112>Capturing genomic signatures of DNA sequence variation using a standard anonymous microarray platform. Nucleic Acids Res. 2006;34(18):e121. PMID: 17000641</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures changes (expansion, amplification, deletion, mutation) in the sequence of a DNA molecule.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>OBI Biomaterial</obo:IAO_0000119>
<rdfs:label>DNA sequence variation detection assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000439 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000439">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0302890"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">agarose gel</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Performance comparison of capillary and agarose gel electrophoresis for the identification and characterization of monoclonal immunoglobulins. Am J Clin Pathol. 2008 Mar;129(3):451-8. PMID: 18285269</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a material entity resulting from the polymerization of agarose after heating agarose suspended in some buffer solution</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>GROUP: OBI Biomaterial Branch</obo:IAO_0000119>
<rdfs:label xml:lang="en">agarose gel</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000441 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000441">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000005"/>
<obo:IAO_0000111>assay objective</obo:IAO_0000111>
<obo:IAO_0000112>the objective to determine the weight of a mouse.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">an objective specification to determine a specified type of information about an evaluated entity (the material entity bearing evaluant role)</obo:IAO_0000115>
<obo:IAO_0000117>PPPB branch</obo:IAO_0000117>
<obo:IAO_0000119>PPPB branch</obo:IAO_0000119>
<rdfs:label xml:lang="en">assay objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000442 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000442">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_heart</obo:IAO_0000111>
<obo:IAO_0000112>Alan Ruttenberg's heart</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000002"/>
<obo:IAO_0000115 xml:lang="en">The heart is a muscular organ found in all vertebrates that is responsible for pumping blood throughout the blood vessels by repeated, rhythmic contractions</obo:IAO_0000115>
<obo:IAO_0000117>Person:Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Heart</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000230"/>
<rdfs:label>obsolete_heart</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000443 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000443">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000437"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>analyte assay</obo:IAO_0000111>
<obo:IAO_0000112>example of usage: In lab test for blood glucose, the test is the assay, the blood bears evaluant_role and glucose bears the analyte role. The evaluant is considered an input to the assay and the information entity that records the measurement of glucose concentration the output</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An assay with the objective to capture information about the presence, concentration, or amount of an analyte in an evaluant.</obo:IAO_0000115>
<obo:IAO_0000117>Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>Alan Ruttenberg</obo:IAO_0000119>
<obo:IAO_0000119>Bjoern Peters</obo:IAO_0000119>
<obo:IAO_0000119>Helen Parkinson</obo:IAO_0000119>
<obo:IAO_0000119>OBI Planned process branch</obo:IAO_0000119>
<obo:IAO_0000119>Philippe Rocca-Serra</obo:IAO_0000119>
<rdfs:label>analyte assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000444 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000444">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000274"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>target of material addition role</obo:IAO_0000111>
<obo:IAO_0000112>peritoneum of an animal receiving an interperitoneal injection; solution in a tube receiving additional material; location of absorbed material following a dermal application.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A role of a material entity that is realized in an "adding a material entity into a target" process where the bearer of the role (the target) receives the addition of another material entity.</obo:IAO_0000115>
<obo:IAO_0000116>From Branch discussion with BP, AR, MC -- there is a need for the recipient to interact with the administered material. for example, a tooth receiving a filling was not considered to be a target role.</obo:IAO_0000116>
<obo:IAO_0000117>GROUP: Role Branch</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">target of material addition role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000445 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000445">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000414"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>mass measurement assay</obo:IAO_0000111>
<obo:IAO_0000112>The patients was weighed and mass was determined to be 47 kilograms</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that determines the mass of an evaluant</obo:IAO_0000115>
<obo:IAO_0000117>Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>mass measurement assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000446 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000446">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_identification</obo:IAO_0000111>
<obo:IAO_0000112>DNA cleavage assay for the identification of topoisomerase I inhibitors. Nat Protoc. 2008;3(11):1736-50. PMID: 18927559</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000124"/>
<obo:IAO_0000115 xml:lang="en">a process by which the identity (what a thing is) of a material entity is established within a certain confidence interval</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_identification</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000447 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000447">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002176"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000414"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0005216"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>intracellular electrophysiology recording assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An electrophysiology assay where the recording location of the electrode is intracellular.</obo:IAO_0000115>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000119>Frank Gibson</obo:IAO_0000119>
<rdfs:label>intracellular electrophysiology recording assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000448 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000448">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000038"/>
<obo:IAO_0000111>packed column</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A packed column is a chromatography column where the particles of the solid stationary phase or the support coated with a liquid stationary phase may fill the whole inside volume of the tube.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http:www.iupac.org/publications/pac/1993/pdf/6504x0819.pdf></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01218</obo:IAO_0000119>
<rdfs:label>packed column</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000449 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000449">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_defined_output</obo:IAO_0000111>
<obo:IAO_0000112>example of subclass: normalized data set - A normalized data set is a data set that is produced as the output of a normalization data transformation.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000121"/>
<obo:IAO_0000115 xml:lang="en">This is only a placeholder for defined classes, as are its siblings _defined_material and _defined protocol application. Its children should be defined classes constructed as output of a process.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: James Malone</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000226"/>
<rdfs:label>obsolete_defined_output</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000450 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000450">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000245"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000014"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000245"/>
<obo:IAO_0000111 xml:lang="en">regulatory agency</obo:IAO_0000111>
<obo:IAO_0000112>The US Environmental Protection Agency</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A regulatory agency is a organization that has responsibility over or for the legislation (acts and regulations) for a given sector of the government.</obo:IAO_0000115>
<obo:IAO_0000117>GROUP: OBI Biomaterial Branch</obo:IAO_0000117>
<obo:IAO_0000119>WEB: en.wikipedia.org/wiki/Regulator</obo:IAO_0000119>
<rdfs:label xml:lang="en">regulatory agency</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000451 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000451">
<owl:equivalentClass>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000100"/>
<obo:IAO_0000111>normalized data set</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A data set that is produced as the output of a normalization data transformation.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: James Malone</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Melanie Courtot</obo:IAO_0000117>
<rdfs:label xml:lang="en">normalized data set</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000453 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000453">
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<obo:IAO_0000111 xml:lang="en">measure function</obo:IAO_0000111>
<obo:IAO_0000112>A glucometer measures blood glucose concentration, the glucometer has a measure function.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">Measure function is a function that is borne by a processed material and realized in a process in which information about some entity is expressed relative to some reference.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000117>PERSON:Frank Gibson</obo:IAO_0000117>
<rdfs:label xml:lang="en">measure function</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000454 -->
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0005216"/>
</owl:Restriction>
</owl:someValuesFrom>
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<obo:IAO_0000111>extracellular electrophysiology recording assay</obo:IAO_0000111>
<obo:IAO_0000112>The recording of a spike train in the caudate nucleus of a monkey where the electrodes are extra cellular, i.e. not in the neuron</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An electrophysiology assay where the recording location of the electrode is extracellular.</obo:IAO_0000115>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000117>Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000119>Frank Gibson</obo:IAO_0000119>
<rdfs:label>extracellular electrophysiology recording assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000455 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000455">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
<rdfs:subClassOf>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000079"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">consume data function</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">Process data function is a function that is borne by in a material entity by virtue of its structure. When realized the material entity consumes data.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Melanie Courtot</obo:IAO_0000117>
<rdfs:label xml:lang="en">consume data function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000456 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000456">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000005"/>
<obo:IAO_0000111>material transformation objective</obo:IAO_0000111>
<obo:IAO_0000112>The objective to create a mouse infected with LCM virus. The objective to create a defined solution of PBS.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">an objective specifiction that creates an specific output object from input materials.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">artifact creation objective</obo:IAO_0000118>
<obo:IAO_0000119>GROUP: OBI PlanAndPlannedProcess Branch</obo:IAO_0000119>
<rdfs:label xml:lang="en">material transformation objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000457 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000457">
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000458"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
</owl:Restriction>
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<rdfs:subClassOf>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>manufacturing</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A planned process with the objective to produce a processed material which will have a function for future use.</obo:IAO_0000115>
<obo:IAO_0000116>A person or organization (having manufacturer role) is a participant in this process</obo:IAO_0000116>
<obo:IAO_0000116>Manufacturing implies reproducibility and responsibility AR</obo:IAO_0000116>
<obo:IAO_0000116 xml:lang="en">This includes a single scientist making a processed material for personal use.</obo:IAO_0000116>
<obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>GROUP: OBI PlanAndPlannedProcess Branch</obo:IAO_0000119>
<rdfs:label xml:lang="en">manufacturing</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000458 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000458">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
<obo:IAO_0000111>manufacturing objective</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">is the objective to manufacture a material of a certain function (device)</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>GROUP: OBI PlanAndPlannedProcess Branch</obo:IAO_0000119>
<rdfs:label xml:lang="en">manufacturing objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000463 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000463">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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</owl:Restriction>
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<obo:IAO_0000111>column chromatography detector</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">There is a wide range of detectors available for both GC and LC each having their own particular areas of application. In general the more catholic the response, the less sensitive the detector and the most sensitive detectors are those that have a specific response. The performance of all detectors should be properly specified so that the user can determine which is most suitable for a specific application. Such specifications are also essential to compare the performance of different detectors supplied by alternative instrument manufactures. Detector specifications should be presented in a standard form and in standard units, so that detectors can be compared that function on widely different principles.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.chromatography-online.org/Principles/Basic-Chromatograph/Detector/rs56.html></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01077</obo:IAO_0000119>
<obo:IAO_0000232>chromatography detector, defined class/xps</obo:IAO_0000232>
<rdfs:label>column chromatography detector</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000464 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000464">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000555"/>
<obo:IAO_0000111>Bruker autosampler</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A Bruker autosampler is an autosampler made by Bruker.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400209</obo:IAO_0000119>
<rdfs:label>Bruker autosampler</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000465 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000465">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000038"/>
<obo:IAO_0000111>organic acid column</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An organic acid column is a chromatography column which enables (reversed-phase) separation of hydrophilic aliphatic and aromatic organic acids with UV detection. Organic acid columns allow retention of polar and apolar organic acids and are hydrolysis resistant.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01099</obo:IAO_0000119>
<rdfs:label>organic acid column</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000466 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000466">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000637"/>
<obo:IAO_0000111>thermal conductivity detector</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The most commonly used detector in preparative GC is the thermal conductivity detector (hot wire detector). Even this detector, however, is often too sensitive and has too high a flow impedance. Under such circumstances, the procedure mentioned above must be employed. The eluent from the preparative column is split and a small portion diverted through the detector (sometimes with further dilution with carrier gas to reduce sensitivity).</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000118>TCD, hot wire detector</obo:IAO_0000118>
<obo:IAO_0000119>WEB:<http://www.chromatography-online.org/Preparative/Apparatus/Detectors/rs27.html></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01084</obo:IAO_0000119>
<rdfs:label>thermal conductivity detector</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000467 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000467">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000597"/>
<obo:IAO_0000111>Bruker US 2 NMR magnet</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An actively-shielded superconducting magnet from Bruker that combines Bruker BioSpin's advanced, proprietary UltraShield active shielding and UltraStabilized sub-cooling technologies. This shielded and stabilized (US2) magnet system delivers high sensitivity and spectral dispersion.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.bruker-biospin.com/nmr_magnets_950us2.html></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400189</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
<rdfs:label>Bruker US 2 NMR magnet</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000468 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000468">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000038"/>
<obo:IAO_0000111>protein column</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A protein column is a chromatography column used for the separation of complex protein mixtures. Protein columns enable sample desalting, followed by chromatographic separation or fractionation of complex protein samples, e.g. immunodepleted serum or plasma proteins.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01238</obo:IAO_0000119>
<obo:IAO_0000232>refactor as defined class</obo:IAO_0000232>
<rdfs:label>protein column</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000469 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000469">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000485"/>
<obo:IAO_0000111>solvent mixer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A liquid chromatography device that mixes different solvents, e.g. under high pressure and in differrent volumes ranging from 5 ml to 5 L capacity. Powerful magnetic mixers provide vigorous agitation required for high pressure reaction chemistry.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01072</obo:IAO_0000119>
<rdfs:label>solvent mixer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000470 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000470">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>mass spectrometry assay</obo:IAO_0000111>
<obo:IAO_0000112>Identification of a proteins cut out from a 2D gel by cleaving it into peptides using trypsin digestion using electrospray ionizatino to ensure the peptides are charged, and accelerating them with an electro magnetic field in which the flight path is determined by the mass / charge ratio of the peptides. Comparing the mass/charge ratio of peptides in the proteins with databases of protein sequences allows to identify which protein gave rise to the peptides.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that identifies the amount and type of material entities present in a sample by fragmenting the sample and measuring the mass-to-charge ratio of the resulting particles.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>Philippe Rocca-Serra</obo:IAO_0000119>
<rdfs:label>mass spectrometry assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000471 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000471">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000011"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000059"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<obo:IAO_0000111>study design execution</obo:IAO_0000111>
<obo:IAO_0000112>injecting a mouse with PBS solution, weighing it, and recording the weight according to a study design.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">a planned process that carries out a study design</obo:IAO_0000115>
<obo:IAO_0000116>removed axiom has_part some (assay or 'data transformation') per discussion on protocol application mailing list to improve reasoner performance. The axiom is still desired.</obo:IAO_0000116>
<obo:IAO_0000119>branch derived</obo:IAO_0000119>
<obo:IAO_0000232>6/11/9: edited at workshop. Used to be: study design execution is a process with the objective to generate data according to a concretized study design. The execution of a study design is part of an investigation, and minimally consists of an assay or data transformation.</obo:IAO_0000232>
<rdfs:label>study design execution</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000473 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000473">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000464"/>
<obo:IAO_0000111>Bruker NMR Case sample changer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The NMR Case is an economical NMR sample changer for laboratories with modest automation needs. It expands the maximum number of samples your spectrometer can process during unattended operation to 24. The NMR Case consists of multiple components. The NMR Case exchange module installed atop your cryostat. The two front legs are adjustable, making the NMR Case compatible with many different cryostats.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.bruker-biospin.com/automation.html></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400203</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
<rdfs:label>Bruker NMR Case sample changer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000474 -->
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<obo:IAO_0000111>nano pump system</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pump system optimized for nano flow chromatography.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01052</obo:IAO_0000119>
<rdfs:label>nano pump system</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000475 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000475">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000498"/>
<obo:IAO_0000111>Bruker AutoClean system</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">NMR tubes are often used once and discarded, creating needless waste. With the Bruker BioSpin Autoclean system you can now recycle 5mm, 3mm, or 5mm/3mm step-down (Wilmad 520-1B) NMR tubes. AutoClean NMR Tube Washing System is a simple way to recoup the substantial investment your organization makes in quality NMR tubes, and cut back on needless waste material.</obo:IAO_0000115>
<obo:IAO_0000116>washing system/NMR tube washing system, XPS: device has function washing</obo:IAO_0000116>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.used-line.com/c5983250s10028-Bruker_Biospin_NMR_Autoclean_Nuclear_Magnetic_Resonance_Organic_Solvents.htm></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400205</obo:IAO_0000119>
<rdfs:label>Bruker AutoClean system</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000476 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000476">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000504"/>
<obo:IAO_0000111>manual injection system</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The traditional hardware system that allows a human to inject a sample into an inlet by hand, using a syringe.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01064</obo:IAO_0000119>
<rdfs:label>manual injection system</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000477 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000477">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000611"/>
<obo:IAO_0000111>Varian GEMINI spectrometer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An older Varian Broadband NMR spectrometer.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400239</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
<rdfs:label>Varian GEMINI spectrometer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000478 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000478">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000048"/>
<obo:IAO_0000111>column connector</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that connects two or more columns together in a functional way with leak-tight connection, low dead volume, low thermal mass and high inertness.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01236</obo:IAO_0000119>
<obo:IAO_0000232>chromatography device</obo:IAO_0000232>
<rdfs:label>column connector</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000479 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000479">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000516"/>
<obo:IAO_0000111>solid NMR probe</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An NMR probe that is designed to hold a solid sample.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400243</obo:IAO_0000119>
<obo:IAO_0000232>NMR device</obo:IAO_0000232>
<rdfs:label>solid NMR probe</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000480 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000480">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000561"/>
<obo:IAO_0000111>Bruker high resolution probe</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">BRUKER BIOSPIN's experienced Research & Development group not only delivers top-performance probes for the more common experiments, but also a wealth of special probes for almost any application. For high resolution (HR) NMR we offer probes with a variety of important characteristics and features.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000118>HR Probe</obo:IAO_0000118>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400223</obo:IAO_0000119>
<obo:IAO_0000232>NMR probe</obo:IAO_0000232>
<rdfs:label>Bruker high resolution probe</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000481 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000481">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000485"/>
<obo:IAO_0000111>chromatography detector</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A chromatography detector is a device that locates in the dimensions of space and time, the positions of the components of a mixture that has been subjected to a chromatographic process and thus permits the senses to appreciate the nature of the separation. Defining characteristics are Dynamic Range, Response Index or Linearity, Linear Dynamic range, Detector Response, Detector Noise Level, Detector Sensitivity or Minimum Detectable Concentration, Total System Dispersion, Sensor Dimensions, Detector Time Constant, Pressure Sensitivity, Flow Sensitivity, Operating Temperature Range.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.chromatography-online.org/GC-Detectors/Classification/rs1.html></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01012</obo:IAO_0000119>
<rdfs:label>chromatography detector</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000482 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000482">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000038"/>
<obo:IAO_0000111>normal phase column</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A normal phase column is a chromatography column in which the stationary phase is more polar than the mobile phase. Its counterpart is the reversed phase column.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01097</obo:IAO_0000119>
<rdfs:label>normal phase column</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000483 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000483">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000599"/>
<obo:IAO_0000111>APOLLO console</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The APOLLO is a compact, modular, multiple-DSP, Windows XP Professional-based console that can be equipped with up to 8 DDS-based RF transmitter channels configurable from 2 kHz to 3.5 GHz. Each transmitter channel produces a nominal 1V output and has the most agile frequency, phase and amplitude control of any system on the market. An array of additional options are available including multiple RF transmitters, linear high-power RF amplifiers, digital receiver arrays, low noise figure preamplifiers, a gradient control system, shim unit, MAS spin-speed controller, variable temperature unit, digital lock system and probe/coil interface. With its numerous options, the Apollo can be configured for any NMR, NQR or MRI application.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.tecmag.com/apollo.htm></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400249</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument/NMR console</obo:IAO_0000232>
<rdfs:label>APOLLO console</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000484 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000484">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<obo:IAO_0000111>NMR sample holder</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An NMR sample holder is the part of an NMR instrument, which carries the NMR probe,sample tube and the nmr sample.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400212</obo:IAO_0000119>
<obo:IAO_0000232>NMR device</obo:IAO_0000232>
<rdfs:label>NMR sample holder</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000485 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000485">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000932"/>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000372"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>chromatography instrument</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Any instrument that is used to carry out a chromatography experiment.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01262</obo:IAO_0000119>
<obo:IAO_0000232>chromatography device, defined class?</obo:IAO_0000232>
<rdfs:label>chromatography instrument</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000486 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000486">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000566"/>
<obo:IAO_0000111>continuous wave NMR instrument</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Continuous wave NMR spectrometers are similar to optical spectrometers, but the sample is held in a strong magnetic field, where the frequency of the source is slowly scanned (in some instruments, the source frequency is held constant, and the field is scanned).</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://teaching.shu.ac.uk/hwb/chemistry/tutorials/molspec/nmr3.htm></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400283</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
<rdfs:label>continuous wave NMR instrument</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000487 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000487">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000566"/>
<obo:IAO_0000111>fourier transformation NMR instrument</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">In fourier transformation NMR, all frequencies in a spectrum are irradiated simultaneously with a radio frequency pulse. Following the pulse, the nuclei return to thermal equilibrium. A time domain emission signal is recorded by the instrument as the nuclei relax. A frequency domain spectrum is obtained by Fourier transformation.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://teaching.shu.ac.uk/hwb/chemistry/tutorials/molspec/nmr3.htm></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400284</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
<rdfs:label>fourier transformation NMR instrument</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000489 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000489">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000637"/>
<obo:IAO_0000111>nitrogen phosphorous detector</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The nitrogen phosphorus detector (NPD) (sometimes called the thermionic detector) is a very sensitive, specific detector the design of which, is based on the FID. Physically the sensor appears to be very similar to the FID but, in fact, operates on an entirely different principle. The nitrogen phosphorous detector (sometimes called the thermionic detector) is a very sensitive but specific detector that responds almost exclusively to nitrogen and phosphorous compounds. It is based on the flame ionization detector but differs in that it contains a rubidium or cesium silicate (glass) bead situated in a heater coil, a little distance from the hydrogen flame. If the detector is to respond to both nitrogen and phosphorous then the hydrogen flow should be minimal so that the gas does not ignite at the jet. If the detector is to respond to phosphorous only, a large flow of hydrogen is used which is burnt at the jet. The heated bead emits electrons by thermionic emission. These electrons are collected under a potential of a few volts by an appropriately placed anode, and provides a background current. When a solute containing nitrogen or phosphorous is eluted from the column, the partially combusted nitrogen and phosphorous materials are adsorbed on the surface of the bead. The adsorbed material reduces the work function of the surface and, as consequence, the emission of electrons is increased which raises the current collected at the electrode. The sensitivity of the detector to phosphorous is about 10-12 gram per ml and for nitrogen about 10-11 gram per ml at a signal to nose ratio of 2. The alkali bead as a finite life and needs regular replacement.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.chromatography-online.org/topics/nitrogen/phosphorus/detector.html></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01089</obo:IAO_0000119>
<rdfs:label>nitrogen phosphorous detector</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000490 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000490">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000560"/>
<obo:IAO_0000111>cation exchange column</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cation exchange column is a chromatography column that is used in cation exchange chromatography.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01096</obo:IAO_0000119>
<rdfs:label>cation exchange column</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000491 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000491">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000516"/>
<obo:IAO_0000111>direct detection NMR probe</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An NMR probe designed to allow the direct detection of acquisition nuclei.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400280</obo:IAO_0000119>
<obo:IAO_0000232>NMR device</obo:IAO_0000232>
<rdfs:label>direct detection NMR probe</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000492 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000492">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000464"/>
<obo:IAO_0000111>Bruker B-ACS system</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The Bruker Automatic Sample Changer (B-ACS 60/120), used in conjunction with Bruker DISNMR, UXNMR or XWIN-NMR software, provides dialog-guided facilities which allow the user to easily and effectively perform automatic (continuous) experiments. Features include a 60 or 120 sample capacity, random accessing of samples, positive sample identification with the optional bar code reader, and temperature control of individual samples with the optional sample heater unit.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.bruker-biospin.com/automation.html></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400210</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
<rdfs:label>Bruker B-ACS system</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000493 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000493">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000932"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000372"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>rapid resolution column</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A rapid resolution column is a chromatography column as marketed by Agilent, which is used with a rapid resolution cartridge to ensure a fast chromatography process with good separation resolution.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01102</obo:IAO_0000119>
<rdfs:label>rapid resolution column</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000494 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000494">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000485"/>
<obo:IAO_0000111>liquid chromatography autosampler</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Designed to perform capillary LC with injection of sample volumes ranging from nL to L.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01061</obo:IAO_0000119>
<rdfs:label>liquid chromatography autosampler</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000495 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000495">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000589"/>
<obo:IAO_0000111>vacuum degasser</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A degassing system used for degassing solvents in liquid chromatography. Dissolved gasses, usually nitrogen and oxygen from the air, tend to be evolved in the mobile phase as the pressure is reduced when the mobile phase leaves the liquid chromatography column and enters the detector. Gasses in the mobile phase in the detector can produce completely unacceptable noise and, thus, must be removed. The dissolved gasses were originally removed under vacuum but, unfortunately, are soon replaced if the solvent is left in contact with air at atmospheric pressure. For this reason degassing is now usually carried out by bubbling helium through the mobile phase reservoirs. Secondly, vacuum is used in the thermionic detector. This consists of a device, very similar in design to the thermionic valve which is attached to a vacuum and a small quantity of the eluent from a gas chromatography column allowed to bleed through it. Helium is used as the carrier gas. The presence of solute vapor causes the thermionic current to fall. This type of detector tends to become contaminated rather readily.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.chromatography-online.org/topics/vacuum.html></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01053</obo:IAO_0000119>
<rdfs:label>vacuum degasser</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000496 -->
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<obo:IAO_0000111>capillary column</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A capillary column is a thin tube with a small inner diameter, usually around 0.5 mm.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01066</obo:IAO_0000119>
<rdfs:label>capillary column</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000497 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000497">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000048"/>
<obo:IAO_0000111>sample inlet</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The column inlet (or injector) provides the means to introduce a sample into a continuous flow of carrier gas. The inlet is a piece of hardware attached to the column head.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://en.wikipedia.org/wiki/Gas_chromatography#Inlets></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01044</obo:IAO_0000119>
<obo:IAO_0000232>chromatography device</obo:IAO_0000232>
<rdfs:label>sample inlet</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000498 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000498">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<obo:IAO_0000111>NMR tube washing system</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An automatic cleaning system for NMR tubes that removes previous probe and sample residues in order to allow for tube recycling.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400204</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
<rdfs:label>NMR tube washing system</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000499 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000499">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<obo:IAO_0000111>NMR console</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A component of an NMR instrument that controls the activities of the other components.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400015</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument, TODO: same as or part of acquisition computer?</obo:IAO_0000232>
<rdfs:label>NMR console</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000500 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000500">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000494"/>
<obo:IAO_0000111>dual loop autosampler</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A dual loop autosampler is an autosampler that is designed for handling both analytical (10 mL/min flow rate) to preparative scale sample purification (100 mL/min flow rate).</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.chem.agilent.com/scripts/pds.asp?lpage=17149></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01063</obo:IAO_0000119>
<rdfs:label>dual loop autosampler</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000501 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000501">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>variable wavelength detector</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A chromatography detector, that can detect signals within a certain range at user-defined wavelengths.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01079</obo:IAO_0000119>
<rdfs:label>variable wavelength detector</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000503 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000503">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000596"/>
<obo:IAO_0000111>Bruker LC-NMR platform</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The LC-NMR/MS setup was first introduced by Bruker BioSpin in 1999. An LC-NMR system including a Bruker Peak Sampling Unit (BPSU-36) was coupled with a Bruker Daltonics esquire series ion trap mass spectrometer via a Bruker NMR-MS interface (BNMI). Since October 2004 the Bruker Daltonics microTOF-LC time-of-flight mass spectrometer can also be integrated in an LC-NMR setup.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.bruker-biospin.com/hyphenation_lcnmr_ms.html></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400276</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
<obo:IAO_0000232>hyphenated NMR instrument platform</obo:IAO_0000232>
<rdfs:label>Bruker LC-NMR platform</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000504 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000504">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000048"/>
<obo:IAO_0000111>sample injection system</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An automated chromatography system that injects the sample into the chromatography columns in order to increase speed and minimize human involvement in the purification process for better reproducibility.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01057</obo:IAO_0000119>
<obo:IAO_0000232>chromatography device</obo:IAO_0000232>
<rdfs:label>sample injection system</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000505 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000505">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
<rdfs:subClassOf>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>multiple wavelength detector</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A chromatography detector, that can detect many discrete wavelengths in parallel and produces a multiple wavelength chromatographic profile.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01078</obo:IAO_0000119>
<rdfs:label>multiple wavelength detector</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000506 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000506">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000637"/>
<obo:IAO_0000111>photoionization detector</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The selective determination of aromatic hydrocarbons or organo-heteroatom species is the job of the photoionization detector (PID). This device uses ultraviolet light as a means of ionizing an analyte exiting from a GC column. The ions produced by this process are collected by electrodes. The current generated is therefore a measure of the analyte concentration. f the amount of ionization is reproducible for a given compound, pressure, and light source then the current collected at the PID's reaction cell electrodes is reproducibly proportional to the amount of that compound entering the cell. The reason why the compounds that are routinely analyzed are either aromatic hydrocarbons or heteroatom containing compounds (like organosulfur or organophosphorus species) is because these species have ionization potentials (IP) that are within reach of commercially available UV lamps. The available lamp energies range from 8.3 to 11.7 ev, that is, lambda max ranging from 150 nm to 106 nm. Although most PIDs have only one lamp, lamps in the PID are exchanged depending on the compound selectivity required in the analysis.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000118>PID</obo:IAO_0000118>
<obo:IAO_0000119>WEB:<http://www.chemistry.adelaide.edu.au/external/soc-rel/content/pid.htm></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01090</obo:IAO_0000119>
<rdfs:label>photoionization detector</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000507 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000507">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000542"/>
<obo:IAO_0000111>gas generator</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An instrument that generates gases for use with the gas chromatograph. Previously gas was obtained from gas tanks or gas cylinders. However, over the past decade the use of gas generators have become more popular as it avoids having gases at high pressure in the laboratory which is perceived by some as potentially dangerous. In addition, the use of a hydrogen generator avoids the use of a cylinder of hydrogen at high pressure which is also perceived by some as a serious fire hazard despite the fact that they have been used in laboratories, quite safely for nearly a century.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.chromatography-online.org/GC/Gas-Supplies/Pure-Air-Generators./rs5.html></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01033</obo:IAO_0000119>
<obo:IAO_0000232>gas chromatography equipment</obo:IAO_0000232>
<rdfs:label>gas generator</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000508 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000508">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000048"/>
<obo:IAO_0000111>column jacket</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A column jacket is a piece of column chromatography equipment that covers a column in order to ensure thermoisolation and create a controllable thermostatic microenvironment.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01276</obo:IAO_0000119>
<obo:IAO_0000232>chromatography device</obo:IAO_0000232>
<rdfs:label>column jacket</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000509 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000509">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000637"/>
<obo:IAO_0000111>electron capture detector</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The electron capture detector is a GC detector that uses a radioactive Beta emitter (electrons) to ionize some of the carrier gas and produce a current between a biased pair of electrodes. When organic molecules that contain electronegative functional groups, such as halogens, phosphorous, and nitro groups pass by the detector, they capture some of the electrons and reduce the current measured between the electrodes.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000118>ECD</obo:IAO_0000118>
<obo:IAO_0000119>WEB:<http://homepages.onsnet.nu/%7Ealkema/html/whatisgc.html></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01085</obo:IAO_0000119>
<rdfs:label>electron capture detector</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000510 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000510">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000038"/>
<obo:IAO_0000111>reversed phase column</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A reversed phase column is a chromatography column in which the mobile phase is more polar than the stationary phase. Its counterpart is the normal phase column.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01106</obo:IAO_0000119>
<rdfs:label>reversed phase column</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000511 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000511">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000601"/>
<obo:IAO_0000111>injector lubricant</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A lubricant used in liquid chromatography that eases sample injector penetration.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01118</obo:IAO_0000119>
<rdfs:label>injector lubricant</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000512 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000512">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600014"/>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100060"/>
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<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100060"/>
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<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000681"/>
</owl:Restriction>
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<obo:IAO_0000111>isolation of cell population</obo:IAO_0000111>
<obo:IAO_0000112>removing CD4+ cells from PBMCs using magnetic beads.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a process in which a population of cells with certain characteristics is isolated from a larger population</obo:IAO_0000115>
<obo:IAO_0000117>Person: Bjoern Peters</obo:IAO_0000117>
<rdfs:label>isolation of cell population</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000513 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000513">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000599"/>
<obo:IAO_0000111>DISCOVERY console</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The Discovery console is a Windows XP Professional-based, integrated console designed especially for Solid-State NMR. The console includes everything needed to interface to any magnet and solids probe - from computer to cables to duplexing network.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400247</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument/NMR console</obo:IAO_0000232>
<rdfs:label>DISCOVERY console</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000514 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000514">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000596"/>
<obo:IAO_0000111>Bruker AMX series NMR instrument</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A series of older Bruker NMR magnets, now out of production. The Bruker AMX500 has proven an extremely reliable workhorse, with excellent lineshape yielding superior water suppression even without gradients. The Oxford 11.7 Tesla 5.2 cm bore magnet rests on a TMC vibration damping table. Homogeneity is controlled by a BSN-18 and BSN-2 with 19 shim controls. In addition to the 5 mm triple resonance probe, the AMX is equipped with a 10mm broadband observe probe.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.tufts.edu/med/biochemistry/NMR/amx500.html></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400240</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
<rdfs:label>Bruker AMX series NMR instrument</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000515 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000515">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000038"/>
<obo:IAO_0000111>chromatofocusing column</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A chromatofocusing column is a chromatography column in which a resin is equilibrated at one pH and eluted at a second pH. The use of a weak ion-exchange resin causes a pH gradient to be formed at the solvent front owing to the buffering action of the resin. This pH gradient in turn leads to an ordering of proteins by isoelectric point. Molecules of charge sign opposite the resin bind; those of charge sign like the resin do not bind.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.bioprocessintl.com/default.asp?page=glossary&TopicID=1></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01209</obo:IAO_0000119>
<rdfs:label>chromatofocusing column</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000516 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000516">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
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<obo:IAO_0000111>NMR probe</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Part of an NMR instrument that detects the signals emitted from a sample. No single probe can perform the full range of experiments, and probes that are designed to perform more than one type of measurement usually suffer from performance compromises. The probe represents a rather fragile single point of failure that can render an NMR system completely unusable if the probe is dropped or otherwise damaged. Probes are usually characterised by Sample diameter and Frequency.n alt The instrument that transmits and receives radiofrequency to and from the NMR sample.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400014</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
<rdfs:label>NMR probe</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000517 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000517">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<obo:IAO_0000111>NMR magnet</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A magnet which induces a certain frequency (MHz) and which has a certain bore diameter.n alt The NMR signal is a natural physical property of the certain atomic nuclei but it can only be detected with an external magnetic field. A magnet is a fundamental part of an NMR instrument which induces an electromagnetic force field (RF pulse) and by this excites and aligns the spins of the electrons of the NMR acquisition nucleus. It is usually a big (superconducting) electromagnet which is cooled by liquid helium and can be adjusted to a frequency between 200 and 950 MHz. The magnetic field strength is measured in Tesla or Gauss.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400185</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
<rdfs:label>NMR magnet</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000518 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000518">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000038"/>
<obo:IAO_0000111>trap column</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A trap column is a chromatography column which is used prior to a, e.g. mass spectrometry, separation to clean up or concentrate controlled amounts of samples prior to elution to a detector.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01261</obo:IAO_0000119>
<rdfs:label>trap column</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000519 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000519">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000516"/>
<obo:IAO_0000111>flow probe</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An NMR probe that allows the automatized flow-through of a sample. The sample is aspirated via a syringe pump into the Flow probe, the NMR spectrum is acquired and when the experiment is complete, the sample is returned to back to an external source (well plate) or flushed to waste. Sometimes pulsed field gradients (PFG) can be established in flow probes.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.varianinc.com/cgi-bin/nav?products/NMR/accessory/auto_samplers/vast/index&cid=HFIH></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400131</obo:IAO_0000119>
<obo:IAO_0000232>NMR device</obo:IAO_0000232>
<rdfs:label>flow probe</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000520 -->
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000009"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_2000009"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000576"/>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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<obo:IAO_0000111>clinical chemistry assay</obo:IAO_0000111>
<obo:IAO_0000112>Influence of hydroxyethyl starch (6% HES 130/0.4) administration on hematology and clinical chemistry parameters.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay which uses analytical methods to produce measurements and data on the concentration of chemical parameters (analytes) present in a bodily fluid collected from an organism.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>chemical pathology</obo:IAO_0000118>
<obo:IAO_0000118>detection of analyte in blood sample</obo:IAO_0000118>
<obo:IAO_0000119>url:https://en.wikipedia.org/wiki/Clinical_chemistry</obo:IAO_0000119>
<rdfs:label>clinical chemistry assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000521 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000521">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000637"/>
<obo:IAO_0000111>flame ionization detector</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A flame ionization detector is a GC detector that consist of a hydrogen/air flame and a collector plate which are normally heated independently of the chromatographic oven. Heating is necessary in order to prevent condensation of water generated by the flame and also to prevent any hold-up of solutes as they pass from the column to the flame. There is an electrode above the flame to collect the ions formed at a hydrogen/air flame. The number of ions hitting the collector is measured and a signal is generated. Flame ionization detectors are most widely used and generally applicable for gas chromatography and hence is used for routine and general purpose analysis. It is easy to use but destructive of the sample.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000118>FID</obo:IAO_0000118>
<obo:IAO_0000119>WEB:<http://homepages.onsnet.nu/%7Ealkema/html/whatisgc.html></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01197</obo:IAO_0000119>
<rdfs:label>flame ionization detector</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000522 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000522">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000967"/>
<obo:IAO_0000111>vial</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A container made from solid material and primarily used for holding liquid.</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-8844-9165</obo:IAO_0000117>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Vial</obo:IAO_0000119>
<rdfs:label>vial</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000523 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000523">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000566"/>
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<obo:IAO_0000111>magic angle spinning rotor</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A rotor device that holds the NMR sample and enables the adjustment of the orientation of the rotation axis for a sample in a NMR instrument in the magic angle.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000118>MAS rotor</obo:IAO_0000118>
<obo:IAO_0000119>WEB:<http://www.freepatentsonline.com/4352066.html></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400130</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
<rdfs:label>magic angle spinning rotor</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000524 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000524">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000611"/>
<obo:IAO_0000111>Varian VXR spectrometer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A Varian NMR spectrometer.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.scs.uiuc.edu/NMR/instruments/vxr500.php></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400238</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
<rdfs:label>Varian VXR spectrometer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000525 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000525">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000504"/>
<obo:IAO_0000111>splitless GC injector</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Injected sample enters column immediately (while split valve to split vent is closed). Here a sample is introduced into a heated small chamber via a syringe through a septum - the heat facilitates volatilization of the sample and sample matrix. The carrier gas then either sweeps the entirety (splitless mode) or a portion (split mode) of the sample into the column. In split mode, a part of the sample/carrier gas mixture in the injection chamber is exhausted through the split vent.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://en.wikipedia.org/wiki/Gas_chromatography></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01060</obo:IAO_0000119>
<rdfs:label>splitless GC injector</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000526 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000526">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000494"/>
<obo:IAO_0000111>preparative autosampler</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">For preparative LC with injection of sample volumes ranging from L to mL ranges.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01062</obo:IAO_0000119>
<rdfs:label>preparative autosampler</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000527 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000527">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000480"/>
<obo:IAO_0000111>flow high resolution probe</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Hyphenated analytical techniques combining mass spectrometry and chromatography are well-established laboratory tools. The combination of chromatography and NMR has also made its way into the analytical laboratory. Further developments even combine all three techniques into an LC-NMR/NMR-MS system. The use of solid phase extraction provides an efficient interface between chromatography and NMR with demands for special type of flow probes.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000118>flow HR-probe</obo:IAO_0000118>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400195</obo:IAO_0000119>
<obo:IAO_0000232>NMR probe</obo:IAO_0000232>
<rdfs:label>flow high resolution probe</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000528 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000528">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000048"/>
<obo:IAO_0000111>liquid chromatography valve</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A sample valve that must be able to sustain pressures up to 10,000 p.s.i., although it is most likely to operate on a continuous basis, at pressures of 3,000 p.s.i. or less. The higher the operating pressure the tighter the valve seating surfaces must be forced together to eliminate any leak. It follows that any abrasive material, however fine, that passes into the valve can cause the valve seating to become scored each time it is rotated which will ultimately lead to leaks. This will cause the sample size to vary between samples and eventually affect the accuracy of the analysis. It follows that any solid material must be carefully removed from any sample before filling the valve. The sample volume of an internal loop valve is situated in the connecting slot of the valve rotor and can be used only for relatively small sample volumes. Internal sample loop valves provide samples with volumes ranging from 0.1 ml to about 0.5 ml. Valve operation is shown in figure 6. The left-hand side diagram shows the load position. The sample occupies the rotor slot and has been filled by passing the sample from an appropriate syringe through the rotor slot to waste. While loading the sample, the mobile phase supply is passed through the valve directly to the column. To place the sample onto the column, the valve is then rotated and the valve slot containing the sample is now placed between the solvent supply and the column. As a result, the sample is passed into the column by the flow of solvent.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.chromatography-online.org/EC-Dispersion/HPLC-Sample-Valves/rs16.html></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01110</obo:IAO_0000119>
<obo:IAO_0000232>chromatography device</obo:IAO_0000232>
<rdfs:label>liquid chromatography valve</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000529 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000529">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000516"/>
<obo:IAO_0000111>JEOL NMR probe</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An NMR probe that is manufactured by JEOL.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400232</obo:IAO_0000119>
<obo:IAO_0000232>NMR device</obo:IAO_0000232>
<rdfs:label>JEOL NMR probe</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000530 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000530">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000597"/>
<obo:IAO_0000111>Bruker UltraShield Plus NMR magnet</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An NMR magnet of which Brukers claims it is the latest and most advanced self-shielding NMR magnet technology ever developed. These magnets are the ultimate advancement in high performance, actively-shielded NMR solutions. They offer unprecedented shielding performance whilst ensuring no compromise in system homogeneity, stability or cryogenic specifications.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.bruker-biospin.com/nmr_magnets_usplus.html></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400190</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
<rdfs:label>Bruker UltraShield Plus NMR magnet</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000531 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000531">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000561"/>
<obo:IAO_0000111>Bruker CryoProbe</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The Bruker BioSpin CryoProbe is a high-performance cryogenically cooled probe developed for high-resolution applications. It has improved signal/noise (S/N) ratios obtained by reducing the operating temperature of the coil and the pre-amplifier. As a result, the efficiency of the coil is improved and the noise of the coil and the pre-amplifier are reduced.The dramatic increase in the S/N ratio by a factor of 3-4, as compared to conventional probes, leads to a possible reduction in experiment time of up to 16 or a reduction in required sample concentration by a factor of up to 4. The CryoProbes possess key characteristics for NMR analysis:n Significant S/N gains (with moderately salty samples also)n Short pulse widthsn Short ring down timesn Linear behavior in power responsen Gradient capabilityn CryoProbes are available as Triple Resonance, Dual, Selective X Detection, MicroImaging, and Quad Nucleus Probes configurations at 400 MHz and highern All high resolution probes have a lock circuitn All high resolution probes have Z-gradient.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400191</obo:IAO_0000119>
<obo:IAO_0000232>NMR probe</obo:IAO_0000232>
<rdfs:label>Bruker CryoProbe</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000532 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000532">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000048"/>
<obo:IAO_0000111>column cartridge</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that binds the chromatography column and additional connector elements and / or valves or syringes into one physical unity for further processing.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01055</obo:IAO_0000119>
<rdfs:label>column cartridge</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000533 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000533">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000038"/>
<obo:IAO_0000111>affinity column</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An affinity column is a chromatography column that is used in affinity chromatography. Differences in the affinity of molecules to be separated to a stationary phase are used for discriminate retention.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01094</obo:IAO_0000119>
<rdfs:label>affinity column</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000534 -->
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<obo:IAO_0000111>tecmag NMR instrument</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An NMR instrument that is manufactured by tecmag.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400250</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
<rdfs:label>tecmag NMR instrument</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000535 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000535">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000618"/>
<obo:IAO_0000111>gel filtration column</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A Gel filtration column is a chromatography column for size-exclusion chromatography, in which the stationary phase is a gel. The main application of gel filtration chromatography is the fractionation of proteins and other water-soluble polymers.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01104</obo:IAO_0000119>
<rdfs:label>gel filtration column</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000536 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000536">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000485"/>
<obo:IAO_0000111>fraction collector</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A fraction detector is a device that allows regular or specified samples to be taken from a column eluate and stored in a retrievable form. The storage vessels are usually small sample tubes or vials that are oriented in a rotating disk or in a moving belt, there movement usually being controlled by a microprocessor. On receiving a signal from the microprocessor, the next vial is placed under the column outlet and the eluate collected until receiving another signal from the computer. Once the properties of the chromatogram that describes the separation has been ascertained, then the collection program can be defined. The fractions can be collected on a basis of time either at regular intervals or a specific times to collect specific peaks. Alternatively the fractions can be collected by monitoring the detector output and when a peak starts to elute the fraction collector is activated and the peak collected in a specific vial. When the peak returns to base line the column eluate is then directed to waste until the next peak starts eluting. Fraction collectors are in common use with most liquid chromatographs. They are used to collect samples for further purification, subsequent examination by spectroscopic techniques or for biological or organoleptic testing.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.chromatography-online.org/topics/fraction/collector.html></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01073</obo:IAO_0000119>
<rdfs:label>fraction collector</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000537 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000537">
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001404"/>
</owl:Restriction>
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<obo:IAO_0000111>copy number variation profiling assay</obo:IAO_0000111>
<obo:IAO_0000112>Profiling of copy number variations (CNVs) in healthy individuals from three ethnic groups using a human genome 32 K BAC-clone-based array. PMID:18058796</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that determines lost or amplified genomic regions of DNA by comparing genomic DNA originating from tissues from the same or different individuals using specific techniques such as CGH, array CGH, SNP genotyping</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>CNV analysis</obo:IAO_0000118>
<rdfs:label>copy number variation profiling assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000538 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000538">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000592"/>
<obo:IAO_0000111>in-line filter</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A solvent filter that sits between the pump and the injection valve that prevents dust particles, general debris and, to some extent, bacteria from entering the chromatography system. Contaminants can interfere with the low-pressure gradient former or the pump and particles entering valves may interfere with the proper function. The result could cause an increased baseline noise, non-repeatable gradient forming, unreliable flow rate or other interferences. Solvent in-line filters are low-pressure filters and will allow a high flow rate due to a large surface area and large porosity.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.appliedporous.com/frits-chromatography.htm></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01123</obo:IAO_0000119>
<rdfs:label>in-line filter</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000539 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000539">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000516"/>
<obo:IAO_0000111>imaging NMR probe</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An NMR probe that is designed for generating pictures from sample states via NMR imaging.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400244</obo:IAO_0000119>
<obo:IAO_0000232>NMR device</obo:IAO_0000232>
<rdfs:label>imaging NMR probe</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000540 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000540">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000512"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100060"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100060"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>isolation of adherent cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a material separation process in which cells that stick to the container in which they are grown as a cell culture are separated from those in the liquid component of the culture. The output of this process are adherent cells.</obo:IAO_0000115>
<rdfs:label>isolation of adherent cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000541 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000541">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000596"/>
<obo:IAO_0000111>Bruker AC series NMR instrument</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A series of older Bruker NMR magnets, now out of production.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400241</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
<rdfs:label>Bruker AC series NMR instrument</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000542 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000542">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000048"/>
<obo:IAO_0000111>gas chromatography equipment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Any device used in a gas chromatography experiment.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01030</obo:IAO_0000119>
<obo:IAO_0000232>will become defined class/xps</obo:IAO_0000232>
<rdfs:label>gas chromatography equipment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000543 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000543">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000592"/>
<obo:IAO_0000111>syringe filter</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A small membrane filter of defined pore size, that filters samples from a syringe.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01122</obo:IAO_0000119>
<rdfs:label>syringe filter</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000544 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000544">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000383"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>Bruker SampleRail system</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">This Instrument system automatically prepares an NMR sample, inserts it into an NMR magnet, performs NMR experiments on the sample, and transports it back to the preparation system. The SampleRail fulfills the transporting tasks from the preparation system into the NMR magnet and back.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.bruker-biospin.com/automation.html></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400207</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
<rdfs:label>Bruker SampleRail system</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000545 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000545">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000048"/>
<obo:IAO_0000111>column compartment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">For chromatography analyses, the ability to maintain a stable column environment regardless of ambient temperature fluctuations is critical for maintaining retention time precision. In order to ensure such stable conditions at different chromatography steps a column compartment can be installed that ensures e.g. stable temperature of the column in a given step.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01068</obo:IAO_0000119>
<rdfs:label>column compartment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000546 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000546">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000589"/>
<obo:IAO_0000111>capillary pump system</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pump system optimized for capillary chromatography.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01051</obo:IAO_0000119>
<rdfs:label>capillary pump system</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000547 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000547">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
<rdfs:subClassOf>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>evaporative light scattering detector</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The evaporative light scattering detector, as its name implies, utilizes a spray that continuously atomizes the column eluent into small droplets. These droplets are allowed to evaporate, leaving the solutes as fine particulate matter suspended in the atomizing gas.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.chromatography-online.org/HPLC-Detectors/Evaporative-Light-Scattering/rs73.html></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01082</obo:IAO_0000119>
<rdfs:label>evaporative light scattering detector</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000548 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000548">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000512"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000178"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100060"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000681"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>isolation of PBMCs</obo:IAO_0000111>
<obo:IAO_0000112>cells are extracted from whole blood using ficoll, a hydrophilic polysaccharide that separates layers of blood, with monocytes and lymphocytes forming a buffy coat under a layer of plasma. This buffy coat contains the PBMCs.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a process in which cells with a single nucleus are isolated from a blood sample</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: bjoern peters</obo:IAO_0000117>
<obo:IAO_0000119>wiki http://en.wikipedia.org/wiki/PBMC</obo:IAO_0000119>
<rdfs:label>isolation of PBMCs</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000549 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000549">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000485"/>
<obo:IAO_0000111>column cartridger</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A chromatography device where the column cartridge is inserted into and stabilised.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01054</obo:IAO_0000119>
<rdfs:label>column cartridger</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000550 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000550">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000507"/>
<obo:IAO_0000111>nitrogen generator</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A gas generator that generates nitrogen gas.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01034</obo:IAO_0000119>
<rdfs:label>nitrogen generator</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000551 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000551">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000048"/>
<obo:IAO_0000111>needle assembly</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The needle assembly attached to the autosampler, comprises the injector needle that feeds a sample or carrier gas into the inlet</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01065</obo:IAO_0000119>
<rdfs:label>needle assembly</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000552 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000552">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600058"/>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
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<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000415"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600028"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33697"/>
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<rdfs:subClassOf>
<owl:Restriction>
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</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>reverse transcribed polymerase chain reaction</obo:IAO_0000111>
<obo:IAO_0000112>Harmonisation of multi-centre real-time reverse-transcribed PCR results of a candidate prognostic marker in breast cancer: an EU-FP6 supported study of members of the EORTC - PathoBiology Group.
Span PN, Sieuwerts AM, Heuvel JJ, Spyratos F, Duffy MJ, Eppenberger-Castori S, Vacher S, O'Brien K, McKiernan E, Pierce A, Vuaroqueaux V, Foekens JA, Sweep FC, Martens JW.
Eur J Cancer. 2009 Jan;45(1):74-81. PMID: 19008094</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">reverse transcribe pcr is a process which allow amplification of cDNA during a pcr reaction while the cDNA results from a retrotranscription of messenger RNA isolated from a material entity.</obo:IAO_0000115>
<obo:IAO_0000116>3/21/10, BP:Modified definition to clarify that this is not the assay, but the material transformation</obo:IAO_0000116>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>RT-PCR</obo:IAO_0000118>
<obo:IAO_0000118>reverse transcription polymerase chain reaction</obo:IAO_0000118>
<rdfs:label>reverse transcribed polymerase chain reaction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000553 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000553">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000596"/>
<obo:IAO_0000111>Bruker Capillary LC-NMR platform</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Capillary LC-NMR is a hyphenated technique coupling capillary liquid chromatography and NMR, which increases sensitivity dramatically through the use of miniaturization of the chromatographic techniques and NMR detection volume. LC-NMR hyphenated systems separate a mixture into its pure components and couple the output to NMR for automatic sample analysis. The ever increasing need to measure lower sample amounts and lower level impurities demands the highest NMR sensitivity. Traditional LC-NMR systems with relatively large peak volumes are not optimized for such low levels of detection. Bruker BioSpin, together with Waters and Protasis has developed a Capillary LC-NMR system. The latest capillary LC attributes and highest capillary flow probe sensitivity combine with state of the art NMR systems technology. Greater mass sensitivity and faster spectral analysis with smaller sample volumes is possible. This system is ideal for analysis of metabolites and impurities associated with the drug development process.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.bruker-biospin.com/hyphenation_caplcnmr.html></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400279</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
<obo:IAO_0000232>hyphenated NMR instrument platform</obo:IAO_0000232>
<rdfs:label>Bruker Capillary LC-NMR platform</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000554 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000554">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000542"/>
<obo:IAO_0000111>gas chromatography oven</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A gas chromatography oven is an oven with a heated connection between the GC and the MS instrument in a GCMS-analysis, that keeps compounds in the gas phase as they leave the GC oven.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01039</obo:IAO_0000119>
<obo:IAO_0000232>gas chromatography equipment</obo:IAO_0000232>
<rdfs:label>gas chromatography oven</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000555 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000555">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<obo:IAO_0000111>autosampler</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An optional part of an NMR instrument used to hold samples prior to NMR analysis and that sequentially loads these samples into the analytical part of the NMR instrument. n alt The autosampler is an automatic sample changer device.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400002</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
<rdfs:label>autosampler</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000556 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000556">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000589"/>
<obo:IAO_0000111>isocratic pump system</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pump system optimized for isocratic chromatography.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.buchi.com/Isocratic-Pump-System.253.0.html></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01049</obo:IAO_0000119>
<rdfs:label>isocratic pump system</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000557 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000557">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000589"/>
<obo:IAO_0000111>flash pump system</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Any pump system used in flash column chromatography to push the solvent through the column. Better flow rates can be achieved by using a pump or by using compressed gas (e.g. air, nitrogen, or argon) to push the solvent through the column (flash column chromatography).</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01048</obo:IAO_0000119>
<rdfs:label>flash pump system</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000558 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000558">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000611"/>
<obo:IAO_0000111>Varian UNITY INOVA spectrometer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The UNITY INOVA is also the easiest spectrometer to use and is also the choice of those interested in using advanced NMR techniques in their own research, but without becoming, or hiring, an NMR expert. A complete set of turnkey operating environments is available for the UNITY INOVA covering the structure and dynamics of biological macromolecules, small molecules, solids, and imaging. These packages put the combined NMR expertise of the entire Varian NMR community at your fingertips.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.varianinc.com/cgi-bin/nav?products/NMR/spectromet/inova/index&cid=HFIH></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400236</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
<rdfs:label>Varian UNITY INOVA spectrometer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000559 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000559">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000516"/>
<obo:IAO_0000111>liquid NMR probe</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An NMR probe that is designed to hold a liquid sample.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400242</obo:IAO_0000119>
<obo:IAO_0000232>NMR device</obo:IAO_0000232>
<rdfs:label>liquid NMR probe</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000560 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000560">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000038"/>
<obo:IAO_0000111>ion exchange column</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An ion exchange column is a chromatography column that is used in ion exchange chromatography and anion or cation exchange resins to enable separation.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01105</obo:IAO_0000119>
<rdfs:label>ion exchange column</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000561 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000561">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000516"/>
<obo:IAO_0000111>Bruker NMR probe</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An NMR probe that is manufactured by Bruker.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400231</obo:IAO_0000119>
<obo:IAO_0000232>NMR device, TODO: May need no definition.</obo:IAO_0000232>
<rdfs:label>Bruker NMR probe</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000562 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000562">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000518"/>
<obo:IAO_0000111>anion trap column</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An anion trap column is a trap column and ion-exchange column which contains cationic anion-exchange resins.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01277</obo:IAO_0000119>
<rdfs:label>anion trap column</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000563 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000563">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>fluorescene detector</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A single wavelength detector, where the excitation light wavelength is normally a mercury lamp generated high intensity UV light at 253.7 nm. Many substances that fluoresce will be excited by light of this wavelength and hence be detected.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.chromatography-online.org/HPLC-Detectors/Fluorescence/Single-Wavelength-Excitation/rs57.html></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01080</obo:IAO_0000119>
<rdfs:label>fluorescene detector</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000564 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000564">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000479"/>
<obo:IAO_0000111>tecmag EAGLE probe</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The Eagle is a 4 mm 1H/X solid-state MAS probe with a top spinning speed of 18 kHz. Its simple design is robust, reliable and easy to spin. Configurations are available for 200 to 600 MHz wide bore magnets on Tecmag, Bruker, Chemagnetics, JEOL and Varian spectrometers.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400248</obo:IAO_0000119>
<obo:IAO_0000232>NMR probe</obo:IAO_0000232>
<rdfs:label>tecmag EAGLE probe</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000565 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000565">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>electrical conductivity detector</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The electrical conductivity detector measures the conductivity of the mobile phase. There is usually background conductivity which must be backed-off by suitable electronic adjustments. If the mobile phase contains buffers, the detector gives a base signal that completely overwhelms that from any solute usually making detection impossible. Thus, the electrical conductivity detector a bulk property detector. and senses all ions whether they are from a solute or from the mobile phase. In order to prevent polarization of the sensing electrodes, AC voltages must be used and so it is the impedance not the resistance of the electrode system that is actually measured. From a physical chemistry stand point the conductivity of a solution is more important than its resistance. However, it is the resistance (impedance) of the electrode system that determines the current across it. The resistance of any conductor varies directly as its length and inversely as its cross sectional area.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.chromatography-online.org/HPLC-Detectors/Electrical-Conductivity/rs83.html></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01239</obo:IAO_0000119>
<rdfs:label>electrical conductivity detector</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000566 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000566">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
<rdfs:subClassOf>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>NMR instrument</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An Instrument which is used to carry out a NMR analysis of some sample.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000118>MRI scanner</obo:IAO_0000118>
<obo:IAO_0000118>NMR instrument</obo:IAO_0000118>
<obo:IAO_0000118>magnetic resonance imaging scanner</obo:IAO_0000118>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400059</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
<rdfs:label>NMR instrument</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000567 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000567">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000597"/>
<obo:IAO_0000111>Bruker UltraShield NMR magnet</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An NMR magnet manufactured by Bruker that ensures field homogeneity without amplified effects from vibrations or thermal changes. This magnet technology uses active shielding and optimizes coil design.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.bruker-biospin.com/nmr_magnets_us.html?&print=http%3A%2Fitsupportunit.com%2Fawstats%2Ficon%2Fnisum%2Fivuj%2F></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400187</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
<rdfs:label>Bruker UltraShield NMR magnet</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000568 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000568">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000601"/>
<obo:IAO_0000111>piston-seal</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The seal made by a piston in a diaphragm pump. The unique property of the reciprocating diaphragm pump is that the actuating piston does not come into direct contact with the mobile phase and thus, the demands on the piston-cylinder seal are not so great. The diaphragm has a relatively high surface area and thus, the movement of the diaphragm is relatively small and consequently the pump can be operated at a fairly high frequency. High frequency pumping results in a very significant reduction in pulse amplitude and, in addition, high frequency pulses are more readily damped by the column system. Nevertheless, it must be emphasized that diaphragm pumps are not pulseless.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.chromatography-online.org/HPLC/Basic-HPLC/Pump/Diaphragm/rs15.html></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01116</obo:IAO_0000119>
<rdfs:label>piston-seal</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000569 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000569">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000637"/>
<obo:IAO_0000111>mass selective detector</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A mass selective detector is a GC detector that uses mass spectrometry. It is based upon the ionization of solute molecules in the ion source and the separation of the ions generated on the basis of their mass/charge ratio by an analyzer unit. This may be a magnetic sector analyzer, a quadruple mass filter, or an ion trap. Ions are detected by a dynode electron multiplier.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000118>mass spectrometry detector</obo:IAO_0000118>
<obo:IAO_0000119>WEB:<http://homepages.onsnet.nu/%7Ealkema/html/whatisgc.html></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01198</obo:IAO_0000119>
<rdfs:label>mass selective detector</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000570 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000570">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000038"/>
<obo:IAO_0000111>spin column</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A spin column is a chromatography column which is suitable for putting it into a centrifuge. A spin column enforces separation through increased G-forces while spinning the column in a centrifuge. It is often used in DNA gel extraction kits.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01232</obo:IAO_0000119>
<rdfs:label>spin column</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000571 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000571">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000245"/>
</owl:unionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
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<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000457"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>manufacturer role</obo:IAO_0000111>
<obo:IAO_0000112>With respect to The Accuri C6 Flow Cytometer System, the organization Accuri bears the role manufacturer role. With respect to a transformed line of tissue culture cells derived by a specific lab, the lab whose personnel isolated the cll line bears the role manufacturer role. With respect to a specific antibody produced by an individual scientist, the scientist who purifies, characterizes and distributes the anitbody bears the role manufacturer role.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Manufacturer role is a role which inheres in a person or organization and which is realized by a manufacturing process.</obo:IAO_0000115>
<obo:IAO_0000117>GROUP: Role Branch</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>manufacturer role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000572 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000572">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000048"/>
<obo:IAO_0000111>transfer line</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A combination of devices that are used in connection with a sampling head for transferring components of an applied sample to the analyzing part of a chromatography system.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.freepatentsonline.com/5702671.html></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01235</obo:IAO_0000119>
<obo:IAO_0000232>chromatography device</obo:IAO_0000232>
<rdfs:label>transfer line</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000573 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000573">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000589"/>
<obo:IAO_0000111>gradient pump system</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pump system optimized for gradient chromatography.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.buchi.com/Gradient-Pump-System.531.0.html></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01050</obo:IAO_0000119>
<rdfs:label>gradient pump system</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000574 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000574">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000038"/>
<obo:IAO_0000111>high temperature column</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A high temperature column is a chromatography column which is suitable for and withstands very high temperatures in chromatography ovens.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01233</obo:IAO_0000119>
<rdfs:label>high temperature column</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000575 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000575">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000597"/>
<obo:IAO_0000111>Bruker Ultrastabilized NMR magnet</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An NMR magnet manufactured by Bruker for Ultra-High Field NMR, available from 750 MHz to 900 MHz, which provides reliable operation at reduced temperature and ambient pressure via being rigidly mounted and stabilized.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.bruker-biospin.com/nmr_magnets_ultrastabilized.html?&print=http%3A%2Fitsupportunit.com%2Fawstats%2Ficon%2Fnisum%2Fivuj%2F></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400188</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
<rdfs:label>Bruker Ultrastabilized NMR magnet</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000576 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000576">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>scattered molecular aggregate</obo:IAO_0000111>
<obo:IAO_0000112>the sodium and chloride ions in a glass of salt water</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a material entity that consists of all the molecules of a specific type that are located in some bounded region and which is part of a more massive material entity that has parts that are other such aggregates</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON: Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">Collective</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">Discussion in Karslruhe with, among others, Alan Rector, Stefan Schulz, Marijke Keet, Melanie Courtot, and Alan Ruttenberg. With inspiration from the paper Granularity, scale and collectivity: When size does and does not matter, Alan Recto, Jeremy Rogers, Thomas Bittner, Journal of Biomedical Informatics 39 (2006) 333-349</obo:IAO_0000119>
<rdfs:label xml:lang="en">scattered molecular aggregate</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000577 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000577">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_molecular concentration</obo:IAO_0000111>
<obo:IAO_0000112>the phosphate concentration should be 0.1M</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A concentration is a relational quality that inheres in a material entity towards molecular scattered aggregate that is part of it by virtue of some ratio of masses of the two or the counts of the grains of the two or volume occupied by the larger material entity.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000119>Discussion in Karslruhe, Oct 2008, with, among others, Alan Rector, Stefan Schulz, Marijke Keet, Melanie Courtot, and Alan Ruttenberg.</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<rdfs:label>obsolete_molecular concentration</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000578 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000578">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000836"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000566"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>NMR sample tube</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The sample-tube holds the NMR sample and sits in the nmr probe. It is usually a glass tube of 5-20mm diameter.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400132</obo:IAO_0000119>
<obo:IAO_0000232>NMR device</obo:IAO_0000232>
<rdfs:label>NMR sample tube</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000579 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000579">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000611"/>
<obo:IAO_0000111>Varian UNITY spectrometer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The predecessor series of the Varian UNITY INOVA spectrometer.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.scs.uiuc.edu/NMR/instruments/u400.php></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400237</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
<rdfs:label>Varian UNITY spectrometer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000580 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000580">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000596"/>
<obo:IAO_0000111>AVANCE II spectrometer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A spectrometer suitable for metabolomics and in vivo NMR studies but structural analysis of small molecules and low molecular weight proteins can also be performed. To accomplish these studies there are six probe-heads available. A successor, the AVANCE III came out recently.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://cermax.itqb.unl.pt/mambo/en/index.php?option=com_content&task=view&id=36&Itemid=93></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400197</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
<rdfs:label>AVANCE II spectrometer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000581 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000581">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000478"/>
<obo:IAO_0000111>y-column connector</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A column connector that connects one column on one side with two columns at the other side, hence building a Y shaped structure.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01237</obo:IAO_0000119>
<rdfs:label>y-column connector</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000582 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000582">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000596"/>
<obo:IAO_0000111>Bruker LC-NMR/MS platform</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Includes the connection to a high-resolution TOF-LC-MS system.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400277</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
<obo:IAO_0000232>hyphenated NMR instrument platform</obo:IAO_0000232>
<rdfs:label>Bruker LC-NMR/MS platform</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000583 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000583">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>refractive index detector</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">For analyzing non-UV absorbing substances, such as carbohydrates, lipids and polymers. This is also the detector of choice for gel permeation chromatography. The refractive index detector is one of the least sensitive LC detectors. It is very sensitive to changes in ambient temperature, pressure changes, flow-rate changes and can not be used for gradient elution. Despite these many disadvantages, this detector is extremely useful for detecting those compounds that are nonionic, do not adsorb in the UV, and do not fluoresce. There are many optical systems used in refractive index detectors but one of the most common is the differential refractive index detector.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.chromatography-online.org/HPLC/Refractive-Index/rs33.html></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01081</obo:IAO_0000119>
<rdfs:label>refractive index detector</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000584 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000584">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000560"/>
<obo:IAO_0000111>anion exchange column</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An anion exchange column is a chromatography column that is used in anion exchange chromatography and which enables the separation of anion mixtures.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01095</obo:IAO_0000119>
<rdfs:label>anion exchange column</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000586 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000586">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000038"/>
<obo:IAO_0000111>plunger column</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A plunger column is a chromatography column with adjustable heigth control. By means of an adjustable endpiece (plunger) the user can adjust the column length without disturbing the packed bed. Plunger columns can equalize volume changes and thus avoids dead volumes within the column.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01108</obo:IAO_0000119>
<rdfs:label>plunger column</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000588 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000588">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000637"/>
<obo:IAO_0000111>flame photometric detector</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The determination of sulfur or phosphorus containing compounds is the job of the flame photometric detector (FPD). This device uses the chemiluminescent reactions of these compounds in a hydrogen/air flame as a source of analytical information that is relatively specific for substances containing these two kinds of atoms. The emitting species for sulfur compounds is excited S2. The lambda max for emission of excited S2 is approximately 394 nm. The emitter for phosphorus compounds in the flame is excited HPO (lambda max = doublet 510-526 nm). In order to selectively detect one or the other family of compounds as it elutes from the GC column, an interference filter is used between the flame and the photomultiplier tube (PMT) to isolate the appropriate emission band. The drawback here being that the filter must be exchanged between chromatographic runs if the other family of compounds is to be detected.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000118>FPD</obo:IAO_0000118>
<obo:IAO_0000119>WEB:<http://www.shsu.edu/~chemistry/FPD/FPD.html></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01091</obo:IAO_0000119>
<rdfs:label>flame photometric detector</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000589 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000589">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000485"/>
<obo:IAO_0000111>chromatography pump system</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Better flow rates can be achieved by using a pump or by using compressed gas (e.g. air, nitrogen, or argon) to push the solvent through the column (flash column chromatography).</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://en.wikipedia.org/wiki/Column_chromatography></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01046</obo:IAO_0000119>
<rdfs:label>chromatography pump system</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000590 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000590">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000561"/>
<obo:IAO_0000111>Bruker 1mm MicroProbe</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Over the past few years there has been a significantly growing demand for miniaturization in all areas ofmodern research and development. Evoked by many exciting applications, there is a need for analytical methods which require less amounts of sample. Bruker BioSpin meets this challenge with a revolutionary NMR probe design: The 1mm MicroProbe. It operates with disposable 1mm capillary sample tubes and the sample volume of 5 microliters enables the use of lowest amounts of sample to run all high resolution NMR experiments with outstanding sensitivity and up to 16 times faster measurements. Due to the TXI-type probe design, the z-gradient coil and the automatic matching and tuning accessory, the 1mm MicroProbe can be used for a wide variety of NMR experiments. The key advantages of this probe include:n up to 4 times higher mass sensitivity than 5mm conventional probes (with respect to the same sample amount)n excellent solvent suppression propertiesn virtually no salt effectn discrete samples in tubes that can be sealed and storedn automation accessory for sample preparation and handling available.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400194</obo:IAO_0000119>
<obo:IAO_0000232>NMR probe</obo:IAO_0000232>
<rdfs:label>Bruker 1mm MicroProbe</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000591 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000591">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000464"/>
<obo:IAO_0000111>Bruker BEST NMR system</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The introduction of biological screening and combinatorial chemistry for chemical synthesis has also introduced new requirements for NMR automation, e.g., the use of well plates for sample input, increased demands on throughput, and the need for quick and simple interpretation of the acquired NMR data.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000118>Bruker Efficient Sample Transfer NMR</obo:IAO_0000118>
<obo:IAO_0000119>WEB:<http://www.bruker-biospin.com/automation.html></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400206</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
<rdfs:label>Bruker BEST NMR system</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000592 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000592">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000601"/>
<obo:IAO_0000111>chromatography detector filter</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An optical filter that is used to obtain monochromatic light of a defined wavelength from detector lamps.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01121</obo:IAO_0000119>
<rdfs:label>chromatography detector filter</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000593 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000593">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000518"/>
<obo:IAO_0000111>cation trap column</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cation trap column is a trap column and ion-exchange column which contains anionic cation-exchange resins.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01278</obo:IAO_0000119>
<rdfs:label>cation trap column</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000594 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000594">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000048"/>
<obo:IAO_0000111>column adapter</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An Adapter that enabled the connection of a column to additional devices.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01113</obo:IAO_0000119>
<obo:IAO_0000232>chromatography device</obo:IAO_0000232>
<rdfs:label>column adapter</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000595 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000595">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>pulsed amperometric detector</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A chromatography detector as used by high-performance anion exchange chromatography that provides sensitive and specific detection of carbohydrates. Pulsed Electrochemical Detection (PED) allows simple, sensitive, and direct detection of numerous polar aliphatic compounds, especially carbohydrates. This technique exploits the electrocatalytic activity of noble metal electrode surfaces to oxidize various polar functional groups. In PED, multi-step potential-time waveforms at Au and Pt electrodes realize amperometric/coulometric detection while maintaining uniform and reproducible electrode activity. The response mechanisms in PED are dominated by the surface properties of the electrode, and, as a consequence, members of each chemical class of compounds produce virtually identical voltammetric responses. Thus, the full potential is realized when combined with high performance liquid chromatography (HPLC).</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000118>PAD</obo:IAO_0000118>
<obo:IAO_0000119>WEB:<http://adsabs.harvard.edu/abs/2004SPIE.5261..103L></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01240</obo:IAO_0000119>
<rdfs:label>pulsed amperometric detector</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000596 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000596">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000566"/>
<obo:IAO_0000111>Bruker NMR instrument</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An NMR instrument that is manufactured by Bruker.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400198</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
<rdfs:label>Bruker NMR instrument</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000597 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000597">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000517"/>
<obo:IAO_0000111>Bruker NMR magnet</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An NMR magnet that is manufactured by Bruker.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400186</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
<rdfs:label>Bruker NMR magnet</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000598 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000598">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000637"/>
<obo:IAO_0000111>ozone-induced chemiluminescence detector</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Although there are many direct ozone chemiluminescent reactions with various gaseous molecules, the incorporation of a conversion step to convert various non-chemiluminescent analytes to a species capable of reacting with ozone to produce chemiluminescence broadens the horizon of this technique tremendously. The conversion of nearly all nitrogen- and sulfur-containing compounds to their respective chemiluminescent species for universal nitrogen and sulfur detection has made nitrogen/sulfur chemiluminescence detection the most widely used analytical methods based upon ozone-induced chemiluminescence. In addition to non-chromatographic applications, nitrogen/sulfur chemiluminescence detection has been adapted to various chromatographic techniques from gas chromatography to liquid and supercritical fluid chromatography as specialized element-specific detectors. The characteristics of these detectors are evaluated and compared to other element-selective detection techniques. The unique features of the chemiluminescence detectors have made them powerful tools in many diverse fields of analytical chemistry.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://sangerhinxtongbr.library.ingentaconnect.com/content/els/00219673/1999/00000842/00000001/art00177></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01088</obo:IAO_0000119>
<rdfs:label>ozone-induced chemiluminescence detector</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000599 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000599">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000499"/>
<obo:IAO_0000111>tecmag NMR console</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An NMR console manufactured by tecmac.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400246</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
<rdfs:label>tecmag NMR console</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000600 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000600">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000566"/>
<obo:IAO_0000111>JEOL NMR instrument</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An NMR instrument that is manufactured by JEOL.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400226</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
<rdfs:label>JEOL NMR instrument</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000601 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000601">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000048"/>
<obo:IAO_0000111>chromatography consumable</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A chromatography consumable is a consumable that is used in a chromatography experiment.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01115</obo:IAO_0000119>
<obo:IAO_0000232>chromatography device</obo:IAO_0000232>
<rdfs:label>chromatography consumable</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000602 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000602">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000048"/>
<obo:IAO_0000111>column frit</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A part of the column content that separates column packing compartments. In radial columns the packing is supported between two cylindrical frits and the gap between represents the bed height or column length. The outer frit is the column inlet and consequently the sample initially has a large area of stationary phase with which to interact. Frits are porous metal products to prevent unwanted particles from entering the chromatography system. These particles may come from the sample, the solvent or debris generated by the chromatography system itself. Such particles entering the system may lead to clogging of capillaries, interference with the chromatography by changing chromatographic parameters or disturbance of the detector function. Characteristics of a frit, besides the diameter and the thickness, is the porosity (pore distribution, density).</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.chromatography-online.org/topics/radial/columns.html></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01070</obo:IAO_0000119>
<obo:IAO_0000232>chromatography device</obo:IAO_0000232>
<rdfs:label>column frit</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000603 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000603">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000038"/>
<obo:IAO_0000111>liquid chromatography column</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A liquid chromatography column is a chromatography column that is used in liquid chromatography, i.e. a column that is provided with a liquid sample mix.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01227</obo:IAO_0000119>
<rdfs:label>liquid chromatography column</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000604 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000604">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000601"/>
<obo:IAO_0000111>detector lamp</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A lamp used in a chromatography detector that excites sample molecules at certain frequencies / emission wavelengths, e.g. Mercury Vapor Lamp (253.7 nm), Zinc Vapor Lamp (2123.9 nm and 307.6 nm), Cadmium Vapor Lamp (228.8, 326.1,340.3, and 346.6 nm). To obtain monochromatic light an appropriate light filter would be needed.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.chromatography-online.org/HPLC/UV-Detectors/Fixed-Wavelength/rs23.html></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01119</obo:IAO_0000119>
<rdfs:label>detector lamp</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000605 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000605">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000048"/>
<obo:IAO_0000111>chart recorder</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The chart recorder is a device that transduces signal-intensities into a graphical peak output: As the separated components of the gas sample emerge into the detector, the change in voltage in the detecting bridge circuit causes a representative peak to be drawn on a chart recorder. The position of the peak along the time axis of the chart measures the component's retention time, which identifies the component. This is directly related to carrier gas flow rate, temperature and column packing and dimensions. The area under each peak is proportional to the concentration of the component of the sample. The area of the peaks inscribed on the chart recorder can be determined by multiplying the height of the peak in mm, by the width of the peak in mm at 1/2 the peak height. The calibration curves for use with the chart recorder are therefore peak area plotted against concentration.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01069</obo:IAO_0000119>
<obo:IAO_0000232>chromatography device</obo:IAO_0000232>
<rdfs:label>chart recorder</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000606 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000606">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000038"/>
<obo:IAO_0000111>open tubular column</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An open tubular column is a chromatography column in which the particles of the solid stationary phase or the support coated with a liquid stationary phase are concentrated on or along the inside tube wall leaving an open, unrestricted path for the mobile phase in the middle part of the tube.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http:www.iupac.org/publications/pac/1993/pdf/6504x0819.pdf></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01219</obo:IAO_0000119>
<rdfs:label>open tubular column</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000607 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000607">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000480"/>
<obo:IAO_0000111>high resolution magic angle spin probe</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Samples that are neither solid nor liquid, being of biological, chemical, or pharmaceutical interest, reveal highly resolved spectra when magic angle spinning is applied. The correct solution is a gradient, such that the field varies along the spinner axis. This so-called Magic Angle Gradient is employed in Brukers high resolution Magic Angle Spinning (hr-MAS) probes, and is implemented in such a way that it is compatible with the stator and does not interfere with the sample eject or insert. Bruker BioSpin has developed a series of dedicated probes for standard bore magnets to accommodate the rapidly expanding field of hr-MAS. These probes are available in double (e.g. 1H and 13C) and triple resonance (e.g. 1H, 13C, 15N) modes and come equipped with a deuterium lock channel. The probes have automatic sample ejection and insertion capability, with the availability of an optional sample changer, enabling fully automated sample runs. Probes can be equipped with an optional B0 gradient, directed along the magic angle, so that gradient spectroscopy can be done used.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000118>high resolution MAS, hr-MAS</obo:IAO_0000118>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400192</obo:IAO_0000119>
<obo:IAO_0000232>NMR probe</obo:IAO_0000232>
<rdfs:label>high resolution magic angle spin probe</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000608 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000608">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000507"/>
<obo:IAO_0000111>hydrogen generator</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A gas generator that generates hydrogen gas.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01035</obo:IAO_0000119>
<rdfs:label>hydrogen generator</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000609 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000609">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000038"/>
<obo:IAO_0000111>glass column</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A glass column is a chromatography column made out of glass that is usually used for larger scale and preparative liquid chromatography separations.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01101</obo:IAO_0000119>
<rdfs:label>glass column</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000610 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000610">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000504"/>
<obo:IAO_0000111>auto injector</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A gas chromatography device that can auto-inject a small number of samples an inlet.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01058</obo:IAO_0000119>
<rdfs:label>auto injector</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000611 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000611">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000566"/>
<obo:IAO_0000111>Varian NMR instrument</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An NMR instrument that is manufactured by Varian.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400234</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
<rdfs:label>Varian NMR instrument</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000612 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000612">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000484"/>
<obo:IAO_0000111>Bruker MATCH tube holder system</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The Bruker Multiple Adjustable Tube Clamp Holder MATCH system is a holder for 100 mm long NMR sample tubes with diameters ranging from micro tubes up to 5 mm NMR tubes. The MATCH insert fits into a standard 10 mm Bruker spinner and is suitable for all non-spinning applications.n The MATCH system provides an easy and cost efficient means of optimizing the signal-to-noise ratio of each sample. By matching the NMR tube diameter to the size of the sample, most of the sample can be placed in the active column of the NMR coil. This leads to an enhanced signal detection compared to diluting the same sample quantity in a larger tube.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000118>Bruker Multiple Adjustable Tube Clamp Holder</obo:IAO_0000118>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400211</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
<rdfs:label>Bruker MATCH tube holder system</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000613 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000613">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000596"/>
<obo:IAO_0000111>Bruker SPE-NMR platform</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A Solid Phase Extraction (SPE) system provides an interface between liquid chromatography (LC) and NMR. For the process of LC-SPE NMR a chromatographic separation is done and the peaks of interest are trapped on an individual SPE cartridge after the column. The peak selection is done either by UV detection or by evaluation of the on-line registered MS or MSn spectra.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400278</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
<obo:IAO_0000232>hyphenated NMR instrument platform</obo:IAO_0000232>
<rdfs:label>Bruker SPE-NMR platform</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000614 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000614">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000048"/>
<obo:IAO_0000111>guard column</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Guard columns are installed between the injection valve and the analytical or preparative column and here will remove contaminants and prolong the lifetime of the columns.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01111</obo:IAO_0000119>
<obo:IAO_0000232>chromatography device</obo:IAO_0000232>
<rdfs:label>guard column</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000615 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000615">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
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<obo:IAO_0000111>protein expression profiling assay</obo:IAO_0000111>
<obo:IAO_0000112>Protein Expression Profiling During Chick Retinal Maturation: A Proteomics-based approach. PMID:19077203</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that determines protein expression and translation activity using protein extracts collected from a material entity.</obo:IAO_0000115>
<obo:IAO_0000117>Phlippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>proteomic analysis</obo:IAO_0000118>
<obo:IAO_0000119>OBI branch derived</obo:IAO_0000119>
<rdfs:label>protein expression profiling assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000616 -->
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<obo:IAO_0000111>high resolution probe with automatic tuning and matching</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The Automatic Tuning and Matching (ATM) option for AVANCE spectrometers is available for double resonance probes in fixed-frequency and broadband tunable configurations with either direct or indirect detection. Thus, for multinuclear operation, as often required for applications in inorganic chemistry, ATM facilitates the accurate setting of 90 degree pulse widths on both observe and decoupling channels for each chosen nucleus and each individual sample - even with full automation. Triple resonance probes in fixed-frequency configurations, as typically used for inverse detection with high-field systems.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000118>High Resolution Probes with Automatic Tuning and Matching, HR_probe_with_ATM</obo:IAO_0000118>
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<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400224</obo:IAO_0000119>
<obo:IAO_0000232>NMR probe</obo:IAO_0000232>
<rdfs:label>high resolution probe with automatic tuning and matching</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000617 -->
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<obo:IAO_0000111>fluorine-induced chemiluminescence detector</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A gas chromatographic detection system based on the low pressure, gas phase chemiluminescence of the reaction mixture of molecular fluorine with organo-sulfur, -selenium, and -tellurium compounds separated from (gas phase) headspace samples. This detector was originally developed in the research group of John Birks at the University of Colorado, USA and was manufactured and sold by Sievers Instruments (Boulder Colorado, USA). This system can be divided up into three parts: the chromatograph, transfer line, and reaction cell; PMT and photon counting electronics; and the molecular fluorine generator.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.shsu.edu/~chm_tgc/publications/JPP/chasteen.htm></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01087</obo:IAO_0000119>
<rdfs:label>fluorine-induced chemiluminescence detector</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000618 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000618">
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<obo:IAO_0000111>size exclusion column</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A size exclusion column is a chromatography column as used in size exclusion chromatography and which enables the separation of mixtures according to differrences in molecular size.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01100</obo:IAO_0000119>
<rdfs:label>size exclusion column</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000619 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000619">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000048"/>
<obo:IAO_0000111>chromatography splitter</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An adjustable restriction that is placed in the waste outlet to allow the necessary pressure to develop at the column inlet to force a flow (q ml/min) through the column. If the flow of mobile phase is Q ml/min then the waste flow will be (Q-q) ml/min. by adjusting the waste flow, the proportion of the sample entering the capillary column can be varied over a wide range of values and the necessary minimum permissible volume for the particular column in use can be selected for analysis. Unfortunately, the fraction taken in this way may not be representative of the original sample. This is due to the individual solutes in the mixture having different diffusivities and, thus, they distribute themselves across the sampling tube in an irregular manner. In general, the components with higher diffusivities (e.g., those solutes of lower molecular weight) will diffuse away from the bulk sample more quickly than those having lower diffusivities.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.chromatography-online.org/EC-Dispersion/GC-Capillary-Columns/rs13.html></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01041</obo:IAO_0000119>
<obo:IAO_0000232>chromatography device</obo:IAO_0000232>
<rdfs:label>chromatography splitter</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000620 -->
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<obo:IAO_0000111>Bruker micro imaging probe</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">For medical, biological and material sciences research, avance imaging systems provide optimal object handling and performance with a variety of samples types. Two classes of imaging probes are available: in vivo probes for handling and sustaining live objects such as animals and plants, and conventional imaging probes for materials samples.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.bruker-biospin.com/probes_microimaging.html></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400225</obo:IAO_0000119>
<obo:IAO_0000232>NMR probe</obo:IAO_0000232>
<rdfs:label>Bruker micro imaging probe</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000621 -->
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<obo:IAO_0000111>custom made column</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A custom made column ia a chromatography column which is specifically tailored according to the needs of the separation as requested by a scientist or working group.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
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<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01234</obo:IAO_0000119>
<rdfs:label>custom made column</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000622 -->
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<obo:IAO_0000111>gel permeation column</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A gel permeation column is a chromatography column which is used in gel permeation chromatography and which employs as the stationary phase a swollen gel made by polymerizing and cross-linking styrene in the presence of a diluent which is a nonsolvent for the styrene polymer. The polymer to be analyzed is introduced at the top of the column and then is elutriated with a solvent. The polymer molecules diffuse through the gel at rates depending on their molecular size.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://composite.about.com/od/glossaries/l/bldef_g2419.htm></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01103</obo:IAO_0000119>
<rdfs:label>gel permeation column</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000623 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000623">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>NMR spectroscopy assay</obo:IAO_0000111>
<obo:IAO_0000112>Metabolic profiling studies on the toxicological effects of realgar in rats by (1)H NMR spectroscopy. Wei L, Liao P, Wu H, Li X, Pei F, Li W, Wu Y. Toxicol Appl Pharmacol. 2008 Nov 25. PMID: 19073202</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An assay that exploits the magnetic properties of certain nuclei (those with a spin) to resonate when placed in particular magnetic field conditions. Instruments recording NMR spectrum and sets of analysis can be used to deduce identity of chemical as well as composition of complex chemical mixtures.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>Nuclear magnetic resonance spectroscopy</obo:IAO_0000118>
<obo:IAO_0000119>url:https://en.wikipedia.org/wiki/Nuclear_magnetic_resonance_spectroscopy</obo:IAO_0000119>
<rdfs:label>NMR spectroscopy assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000624 -->
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<obo:IAO_0000111>Bruker SampleJet system</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Bruker BioSpin introduces the SampleJet, a robot for NMR tube automation. The SampleJet has been consciously designed to meet the growing customer demand for simplicity, versatility and higher throughput in NMR sample tube automation.n The SampleJet utilizes the modern-day industry standard for sample arrangements-the 96 well plate array. Therefore, the samples may be handled by standard lab automation devices before or after the NMR measurement.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.bruker-biospin.com/automation.html></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400208</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
<rdfs:label>Bruker SampleJet system</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000625 -->
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<obo:IAO_0000111>JEOL ECX NMR spectrometer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The ECX series of NMR spectrometers is designed for any laboratory needing an easy-to-use, reliable, routine NMR system. The ECX NMR series is available from 300 to 500 MHz. The console is designed around a modular, digital NMR electronics chassis controlled by an intelligent acquisition computer. For unprecedented flexibility, the JEOL NMR system offers a Windows XP, Mac OSX or LINUX. Both the workstation and spectrometer may be connected to a standard network, allowing seamless remote operation anywhere in the world.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.jeol.com/PRODUCTS/AnalyticalInstruments/NuclearMagneticResonance/ECX/tabid/145/Default.aspx></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400227</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
<rdfs:label>JEOL ECX NMR spectrometer</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000626 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600047"/>
<obo:IAO_0000111>DNA sequencing assay</obo:IAO_0000111>
<obo:IAO_0000112>Illumina (Solexa) sequencing is an example of DNA sequencing</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A sequencing assay which determines information on the sequence of a DNA molecule.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>nucleotide sequencing</obo:IAO_0000118>
<obo:IAO_0000119>url:https://en.wikipedia.org/wiki/DNA_sequencing</obo:IAO_0000119>
<rdfs:label>DNA sequencing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000627 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000627">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000589"/>
<obo:IAO_0000111>quaternary pump system</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pump system that pump and mix up to four different solvents in parallel.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01047</obo:IAO_0000119>
<rdfs:label>quaternary pump system</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000628 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000628">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000038"/>
<obo:IAO_0000111>carbon nanotube column</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Carbon nanotubes (CNTs) are known to have high thermal and mechanical stability and have the potential to be high-performance separation media that utilize the nanoscale interactions. CNT can be applied in long capillary tubes for the development of gas chromatography columns. A film of CNTs can be deposited by chemical vapor deposition (CVD) to form the stationary phase in the open tubular format. Altering the CVD conditions can vary the thickness and the morphology of the CNT film, which opens the possibility of selectivity tuning. The ability to fabricate long tubes coated with CNTs can be readily employed in other gas- and liquid-phase separations as well.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://pubs.acs.org/cgi-bin/abstract.cgi/ancham/2005/77/i21/abs/ac050812j.html></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01107</obo:IAO_0000119>
<rdfs:label>carbon nanotube column</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000629 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000629">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000561"/>
<obo:IAO_0000111>Bruker solid magic angle spinning probe</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Magic angle spinning, nowadays a routine technique for solids NMR, still offers the capability of innovation. The high mechanical performance of MAS probes in conjunction with efficient rf pulse techniques open new exciting fields in solids NMR of biological samples and in the field of quadrupolar nuclei.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000118>solid MAS probe</obo:IAO_0000118>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400193</obo:IAO_0000119>
<obo:IAO_0000232>NMR probe</obo:IAO_0000232>
<rdfs:label>Bruker solid magic angle spinning probe</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000630 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000630">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0030097"/>
</owl:Restriction>
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<obo:IAO_0000111>hematology assay</obo:IAO_0000111>
<obo:IAO_0000112>Co-associations between insulin sensitivity and measures of liver function, subclinical inflammation, and hematology._PMID:18702943</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An assay that studies blood and blood producing organs using a variety of techniques and instruments</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>blood analysis</obo:IAO_0000118>
<obo:IAO_0000118>haematology</obo:IAO_0000118>
<obo:IAO_0000119>OBI branch derived</obo:IAO_0000119>
<rdfs:label>hematology assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000631 -->
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<obo:IAO_0000111>Varian MERCURY spectrometer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">MERCURYplus spectrometers provide superior control, stability, and performance for high-productivity environments. Surface-mount electronics enable a small footprint without compromising data quality. Modular design allows flexible configuration. Direct digital synthesis, linear amplifiers, and other innovative RF and digital technologies enable push-button operation.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.varianinc.com/cgi-bin/nav?varinc/docs/products/NMR/spectromet/mercury/index&cid=975JINLIKLRMPGLMNOILJ></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400235</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
<rdfs:label>Varian MERCURY spectrometer</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000632 -->
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<obo:IAO_0000111>Bruker Metabolic Profiler</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An NMR platform for conducting metabonomics studies, traditional metabolism studies, and analysis of complex mixtures, featuring an Avance NMR spectrometer and a microTOF from Bruker Daltonics. By combining the structural resolving power of NMR with mass accuracy of the microTOF Bruker offers a complete system for metabolic research. The Metabolic Profiler provides a simple, easy to use and inexpensive base-system to acquire the spectroscopic data, needed to do basic metabolic profiling including metabonomic statistical analysis.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.bruker-biospin.com/metabolicprofiler.html></obo:IAO_0000119>
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<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
<obo:IAO_0000232>hyphenated NMR instrument platform</obo:IAO_0000232>
<rdfs:label>Bruker Metabolic Profiler</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000633 -->
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<obo:IAO_0000111>column heater</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">The glass liner can be fitted with a separate heater and the volatilization temperature can, thus, be controlled. This flash heater system is available in most chromatographs. By using a syringe with a long needle, the tip can be made to penetrate past the liner and discharge its contents directly into the column packing. This procedure is called 'on-column injection' and, as it reduces peak dispersion on injection and thus, provides higher column efficiencies, is often the preferred procedure.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.chromatography-online.org/GC/Injection-Devices/Open-Tubular-Column/rs15.html></obo:IAO_0000119>
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<rdfs:label>column heater</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000634 -->
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<obo:IAO_0000111>DNA methylation profiling assay</obo:IAO_0000111>
<obo:IAO_0000112>Genome-wide, high-resolution DNA methylation profiling using bisulfite-mediated cytosine conversion. Reinders J, Delucinge Vivier C, Theiler G, Chollet D, Descombes P, Paszkowski J._PMID:18218979</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures the state of methylation of DNA molecules using genomic DNA collected from a material entity using a range of techniques and instrument such as DNA sequencers and often relying on treatment with bisulfites to ensure cytosine conversion.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>DNA methylation profiling</obo:IAO_0000118>
<obo:IAO_0000119>OBI branch derived</obo:IAO_0000119>
<rdfs:label>DNA methylation profiling assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000635 -->
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<obo:IAO_0000111>JEOL CapNMR probe</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The JEOL ECA and ECX NMR spectrometers now support the MRM/Protasis CapNMR Probe for well plate-based and microvial-based NMR analysis. The CapNMR probe is available at proton frequencies ranging from 300 MHz to 800 MHz in both indirect configurations (e.g. 1H{13C} and 1H {31P}) and also in triple resonance configurations (e.g. 1H{13C, 15N}, 1H{31P, 15N}). Both employ a high-strength z-directed field gradient. The flowprobes come with the choice of two flowcell volumes: a 5 μl flowcell with an NMR active volume of 2.5 μl, and a 10 μl flowcell with an NMR active volume of 5 μl. The fluidic connections are 75 μm i.d. and 1/32 o.d. FEP Teflon with hastelloy unions for exceptional solvent compatibility.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.jeol.com/PRODUCTS/AnalyticalInstruments/NuclearMagneticResonance/CapNMRProbe/tabid/396/Default.aspx></obo:IAO_0000119>
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<obo:IAO_0000232>NMR probe</obo:IAO_0000232>
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<!-- http://purl.obolibrary.org/obo/OBI_0000636 -->
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<obo:IAO_0000111>acquisition computer</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A Computer used for NMR, can be divided into central processing unit (CPU), consisting of instruction, interpretation and arithmetic unit plus fast access memory, and peripheral devices such as bulk data storage and input and output devices (including, via the interface, the spectrometer). Under software control, the computer controls the RF pulses and gradients necessary to acquire data, and process the data to produce spectra or images. Note that devices such as the spectrometer may themselves incorporate small computers.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
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<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400013</obo:IAO_0000119>
<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
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<!-- http://purl.obolibrary.org/obo/OBI_0000637 -->
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<obo:IAO_0000111>gas chromatography detector</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A gas chromatography detector is a chromatography detector that locates in the dimensions of space and time, the positions of the components of a mixture that has been subjected to a gas chromatographic process and thus permits the senses to appreciate the nature of the separation. There is no LC detector that has an equivalent performance to the flame ionization detector (FID) used in GC. In general, LC detectors have sensitivities of two to three orders of magnitude less than their GC counterparts and linear dynamic ranges one to two orders of magnitude lower. Only highly specific LC detectors have sensitivities that can approach those of GC detectors.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000118>FID</obo:IAO_0000118>
<obo:IAO_0000119>WEB:<http://www.chromatography-online.org/GC-Detectors/Classification/rs1.html></obo:IAO_0000119>
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<obo:IAO_0000232>chromatography detector, defined class/xps</obo:IAO_0000232>
<rdfs:label>gas chromatography detector</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000638 -->
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<obo:IAO_0000111>gas purifier</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">Gas purifiers are instruments used for the removal of gas impurities like hydrocarbons, oxygen, and moisture from carrier gas and fuel gases for GC or GC-MS systems.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.sigmaaldrich.com/Area_of_Interest/Analytical__Chromatography/Gas_Chromatography/Accessories/SGT_Gas_Purifier.html></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01036</obo:IAO_0000119>
<obo:IAO_0000232>gas chromatography equipment</obo:IAO_0000232>
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<!-- http://purl.obolibrary.org/obo/OBI_0000639 -->
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<obo:IAO_0000111>material separation objective</obo:IAO_0000111>
<obo:IAO_0000112>The objective to obtain multiple aliquots of an enzyme preparation. The objective to obtain cells contained in a sample of blood.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">is an objective to transform a material entity into spatially separated components.</obo:IAO_0000115>
<obo:IAO_0000117>PPPB branch</obo:IAO_0000117>
<obo:IAO_0000119>PPPB branch</obo:IAO_0000119>
<rdfs:label>material separation objective</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000640 -->
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<obo:IAO_0000111>indirect detection probe</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An NMR probe designed to allow the indirect detection of acquisition nuclei.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
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<obo:IAO_0000232>NMR device</obo:IAO_0000232>
<rdfs:label>indirect detection probe</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000641 -->
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<obo:IAO_0000111>JEOL ECA NMR spectrometer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The ECA series of NMR spectrometers is a high performance, research grade NMR system configurable to a wide range off applications. The ECA NMR is available from 300 to 930 MHz field strengths and is 1GHz ready. The system is designed around a modular, digital NMR electronics chassis controlled from a UNIX or Windows workstation and acquisition system. Both the workstation and spectrometer may be connected to a standard network, allowing seamless remote operation anywhere in the world.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>WEB:<http://www.jeol.com/PRODUCTS/AnalyticalInstruments/NuclearMagneticResonance/ECA/tabid/146/Default.aspx></obo:IAO_0000119>
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<obo:IAO_0000232>NMR instrument</obo:IAO_0000232>
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<!-- http://purl.obolibrary.org/obo/OBI_0000642 -->
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<obo:IAO_0000111>atomic emission detector</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Instead of measuring simple gas phase (carbon containing) ions created in a flame as with the flame ionization detector, or the change in background current because of electronegative element capture of thermal electrons as with the electron capture detector, the AED has a much wider applicability because it is based on the detection of atomic emissions. The strength of the AED lies in the detector's ability to simultaneously determine the atomic emissions of many of the elements in analytes that elute from a GC capillary column (called eluants or solutes in some books). As eluants come off the capillary column they are fed into a microwave powered plasma (or discharge) cavity where the compounds are destroyed and their atoms are excited by the energy of the plasma. The light that is emitted by the excited particles is separated into individual lines via a photodiode array. The associated computer then sorts out the individual emission lines and can produce chromatograms made up of peaks from eluants that contain only a specific element.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000118>AED</obo:IAO_0000118>
<obo:IAO_0000119>WEB:<http://elchem.kaist.ac.kr/vt/chem-ed/sep/gc/detector/aed.htmt></obo:IAO_0000119>
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<rdfs:label>atomic emission detector</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000648 -->
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<obo:IAO_0000111>clustered data set</obo:IAO_0000111>
<obo:IAO_0000112>A clustered data set is the output of a K means clustering data transformation</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A data set that is produced as the output of a class discovery data transformation and consists of a data set with assigned discovered class labels.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: James Malone</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Monnie McGee</obo:IAO_0000117>
<obo:IAO_0000118>data set with assigned discovered class labels</obo:IAO_0000118>
<obo:IAO_0000232>AR thinks could be a data item instead</obo:IAO_0000232>
<rdfs:label xml:lang="en">clustered data set</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000649 -->
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<obo:IAO_0000111>data set of features</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A data set that is produced as the output of a descriptive statistical calculation data transformation and consists of producing a data set that represents one or more features of interest about the input data set.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: James Malone</obo:IAO_0000117>
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<!-- http://purl.obolibrary.org/obo/OBI_0000650 -->
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<obo:IAO_0000111 xml:lang="en">differential expression analysis data transformation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A differential expression analysis data transformation is a data transformation that has an objective of differential expression analysis. Frequently this data transformation involves summarizing or otherwise aggregating signals from various samples categorized into groups, and calculating measures of group differences from these aggregated signals.</obo:IAO_0000115>
<obo:IAO_0000117>Dan Berrios</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Monnie McGee</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">WEB:</obo:IAO_0000119>
<rdfs:label xml:lang="en">differential expression analysis data transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000651 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2000009"/>
<obo:IAO_0000111>urine specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a portion of urine collected from an organism</obo:IAO_0000115>
<obo:IAO_0000116>4/10/2011BP: It seems to me that the editor notes refer to a previous version, and are no longer relevant.</obo:IAO_0000116>
<obo:IAO_0000116>This could be instead a kind of collection of secreted stuff. Among secreted stuff there is passive, and active. urine is secreted, passiv. lavage is secreted, active</obo:IAO_0000116>
<obo:IAO_0000116>are we happy calling collection of urine a material separation?</obo:IAO_0000116>
<rdfs:label>urine specimen</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000652 -->
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<obo:IAO_0000111>material combination</obo:IAO_0000111>
<obo:IAO_0000112>Mixing two fluids. Adding salt into water. Injecting a mouse with PBS.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">is a material processing with the objective to combine two or more material entities as input into a single material entity as output.</obo:IAO_0000115>
<obo:IAO_0000116>created at workshop as parent class for 'adding material into target', which is asymmetric, while combination encompasses all addition processes.</obo:IAO_0000116>
<obo:IAO_0000117>bp</obo:IAO_0000117>
<obo:IAO_0000119>bp</obo:IAO_0000119>
<rdfs:label>material combination</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000653 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000653">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200166"/>
<obo:IAO_0000111 xml:lang="en">fuzzy clustering objective</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A fuzzy clustering objective is a data transformation objective where the aim is to assign input objects (typically vectors of attributes) a probability that a point belongs to a class, where the number of class and their specifications are not known a priori.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: James Malone</obo:IAO_0000119>
<obo:IAO_0000119>PERSON: Ryan Brinkman</obo:IAO_0000119>
<rdfs:label xml:lang="en">fuzzy clustering objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000654 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000654">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000019"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>device setting</obo:IAO_0000111>
<obo:IAO_0000112>Examples, 300V for 4 hours, 200mvolts, 37degrees.A knob set a 300 V is the device setting, the protocol stating to set the instrument to 300V is a device setting specification</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a quality inheres_in some device and is concretization of some (device_setting_specification and is_about a quality of the device</obo:IAO_0000115>
<obo:IAO_0000116>There is some question of whether 'device setting' is really best modelled as a quality. To be revisited after assay terms have been worked through. See https://github.com/obi-ontology/obi/issues/133</obo:IAO_0000116>
<obo:IAO_0000117>PERSON: Frank Gibson</obo:IAO_0000117>
<rdfs:label>device setting</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000655 -->
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
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</owl:Class>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2000009"/>
<obo:IAO_0000111>blood specimen</obo:IAO_0000111>
<obo:IAO_0000112>blood drawn from a human for glucose assay</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">a material entity derived from a portion of blood collected from an organism</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>Bjoern Peters</obo:IAO_0000119>
<rdfs:label>blood specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000656 -->
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200072"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000100"/>
<obo:IAO_0000111>data set of predicted values according to fitted curve</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A data set which is the output of a curve fitting data transformation in which the aim is to find a curve which matches a series of data points and possibly other constraints.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: James Malone</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Monnie McGee</obo:IAO_0000117>
<rdfs:label xml:lang="en">data set of predicted values according to fitted curve</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000658 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000658">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
<obo:IAO_0000111>data representational model</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">The Cytoscape application is commonly used to visualize data representational models about biological entities. It can read and write several serializations of data representational models, including BioPAX.</obo:IAO_0000112>
<obo:IAO_0000112>gene regulatory graph model</obo:IAO_0000112>
<obo:IAO_0000112>phylogenetic tree</obo:IAO_0000112>
<obo:IAO_0000112>protein interaction network</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An information content entity representing the relationships between data items.</obo:IAO_0000115>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000118>data structure</obo:IAO_0000118>
<obo:IAO_0000118>data structure specification</obo:IAO_0000118>
<obo:IAO_0000119>GROUP: OBI</obo:IAO_0000119>
<obo:IAO_0000232>2009-02-28: work on this term has been finalized during the OBI workshop winter 2009</obo:IAO_0000232>
<rdfs:label>data representational model</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000659 -->
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000684"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100051"/>
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<obo:IAO_0000111>specimen collection process</obo:IAO_0000111>
<obo:IAO_0000112>drawing blood from a patient for analysis, collecting a piece of a plant for depositing in a herbarium, buying meat from a butcher in order to measure its protein content in an investigation, collecting a stone from a site</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A planned process with the objective to obtain a material entity for potential use as an input upon which measurements or observations are performed.</obo:IAO_0000115>
<obo:IAO_0000116>Definition updated following discussion on 2024-10-07 OBI dev call.</obo:IAO_0000116>
<obo:IAO_0000116>Note: definition is in specimen creation objective which is defined as an objective to obtain and store a material entity for potential use as an input during an investigation.</obo:IAO_0000116>
<obo:IAO_0000116>Philly2013: A specimen collection can have as part a material entity acquisition, such as ordering from a bank. The distinction is that specimen collection necessarily involves the creation of a specimen role. However ordering cell lines cells from ATCC for use in an investigation is NOT a specimen collection, because the cell lines already have a specimen role.</obo:IAO_0000116>
<obo:IAO_0000116>Philly2013: The specimen_role for the specimen is created during the specimen collection process.</obo:IAO_0000116>
<obo:IAO_0000116>label changed to 'specimen collection process' on 10/27/2014, details see tracker:
http://sourceforge.net/p/obi/obi-terms/716/</obo:IAO_0000116>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000118>specimen collection</obo:IAO_0000118>
<obo:IAO_0000232>5/31/2012: This process is not necessarily an acquisition, as specimens may be collected from materials already in posession</obo:IAO_0000232>
<obo:IAO_0000232>6/9/09: used at workshop</obo:IAO_0000232>
<rdfs:label>specimen collection process</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000660 -->
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</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000100"/>
<obo:IAO_0000111>background corrected data set</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A data set that is produced as the output of a background correction data transformation.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: James Malone</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Melanie Courtot</obo:IAO_0000117>
<rdfs:label xml:lang="en">background corrected data set</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000661 -->
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<obo:IAO_0000111>enzyme-linked immunosorbent assay</obo:IAO_0000111>
<obo:IAO_0000112>1) Detection of IL-2 (analyte) in a cell supernatant (evaluant), using plate bound anti IL-2 antibodies, and a reporter enzyme-linked reporter antibody. 2) Measurement of IgG antibody (analyte) titer in a serum sample (evaluant) using plate bound antigen and a reporter anti-IgG antibody.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay where binding of an enzyme linked antibody to a material entity that is immobilized on solid support is detected utilizing a chemiluminescent reaction. Depending on the setup, the enzyme-linked antibody could be binding directly to the analyte, or it serves as a secondary antibody detecting binding of the primary antibody to the analyte.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000118>ELISA</obo:IAO_0000118>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>enzyme-linked immunosorbent assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000662 -->
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<owl:equivalentClass>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000668"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000100"/>
<obo:IAO_0000111>error corrected data set</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A data set that is produced as the output of an error correction data transformation and consists of producing a data set which has had erroneous contributions from the input to the data transformation removed (corrected for).</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: James Malone</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Monnie McGee</obo:IAO_0000117>
<rdfs:label xml:lang="en">error corrected data set</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000663 -->
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000023"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200179"/>
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</owl:unionOf>
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</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200000"/>
<obo:IAO_0000111 xml:lang="en">class prediction data transformation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A class prediction data transformation (sometimes called supervised classification) is a data transformation that has objective class prediction.</obo:IAO_0000115>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<obo:IAO_0000118>supervised classification data transformation</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">PERSON: James Malone</obo:IAO_0000119>
<rdfs:label xml:lang="en">class prediction data transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000664 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000664">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000891"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002743"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_472552"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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</owl:Restriction>
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</rdfs:subClassOf>
<obo:IAO_0000111>BrdU incorporation assay</obo:IAO_0000111>
<obo:IAO_0000112>The measurement of T cell proliferation as a response to a viral peptide by culturing T cells stimulated with APCs and peptide in the presence of BrdU.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cell proliferation assay in which cells are cultured in the presence of BrdU which is incorporated into newly synthesized DNA of replicating cells (during the S phase of the cell cycle), substituting for thymidine during DNA replication, which can be quantified by BrdU specific antibodies.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>BrdU incorporation assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000665 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000665">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete intracellular cytokine staining assay</obo:IAO_0000111>
<obo:IAO_0000112>Permeabilizing T cells and staining them with fluorescent labeled anti-IFN-gamma antibodies</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The measurement of cytokines within the cytoplasm of a cell by permeabilizing the cell membrane to allow entry of specific antibodies, and counting the stained cells using a flow cytometer.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000118>ICCS</obo:IAO_0000118>
<obo:IAO_0000118>ICS</obo:IAO_0000118>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
<obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/OBI_0000916"/>
<obo:OBI_9991118>intracellular cytokine staining (ICS)</obo:OBI_9991118>
<rdfs:label>obsolete intracellular cytokine staining assay</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000666 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000666">
<owl:equivalentClass>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000660"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200173"/>
</owl:Restriction>
</owl:unionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200000"/>
<obo:IAO_0000111 xml:lang="en">background correction data transformation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A background correction data transformation (sometimes called supervised classification) is a data transformation that has the objective background correction.</obo:IAO_0000115>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: James Malone</obo:IAO_0000119>
<rdfs:label xml:lang="en">background correction data transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000667 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000667">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete MHC multimer staining assay</obo:IAO_0000111>
<obo:IAO_0000112>Measuring T cells that are specific for the SYFPEITHI peptide when presented by the murine MHC molecule H-2 Kd by staining them with a tetramer of peptide loaded MHC complexes.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An MHC multimer assay is an assay that detects T cells capable of binding the MHC:ligand complexes present in the multimer. The multimer is fluorescently labelled. The T cells bound to multimers are counted in a flow cytometer</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000118>MHC tetramer assay</obo:IAO_0000118>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
<obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/OBI_1110179"/>
<obo:OBI_9991118>MHC tetramer/multimer staining</obo:OBI_9991118>
<rdfs:label>obsolete MHC multimer staining assay</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000668 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000668">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200186"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200000"/>
<obo:IAO_0000111 xml:lang="en">error correction data transformation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An error correction data transformation is a data transformation that has the objective of error correction, where the aim is to remove (correct for) erroneous contributions from the input to the data transformation.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000117>Monnie McGee</obo:IAO_0000117>
<obo:IAO_0000119>EDITORS</obo:IAO_0000119>
<rdfs:label xml:lang="en">error correction data transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000669 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000669">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000891"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002743"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_53526"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_53526"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000201"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003368"/>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>tritiated thymidine incorporation assay</obo:IAO_0000111>
<obo:IAO_0000112>The measurement of T cell proliferation as a response to a viral peptide by culturing T cells stimulated with APCs and peptide in the presence of tritiated thymidine, and using a scintillation counter to detect the radioactivity.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cell proliferation assay in which cells are cultured in the presence of tritiated thymidine which is incorporated into newly synthesized DNA of replicating cells (during the S phase of the cell cycle). The radioactivity of tritiated thymidine in a cell is a proxy for cells that were actively replicating.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>tritiated thymidine incorporation assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000671 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000671">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000740"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000747"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>sample from organism</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000002"/>
<obo:IAO_0000115 xml:lang="en">a material obtained from an organism in order to be a representative of the whole</obo:IAO_0000115>
<obo:IAO_0000116>5/29: This is a helper class for now</obo:IAO_0000116>
<obo:IAO_0000116>we need to work on this: Is taking a urine sample a material separation process? If not, we will need to specify what 'taking a sample from organism' entails. We can argue that the objective to obtain a urine sample from a patient is enough to call it a material separation process, but it could dilute what material separation was supposed to be about.</obo:IAO_0000116>
<rdfs:label>sample from organism</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000673 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000673">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000675"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200000"/>
<obo:IAO_0000111 xml:lang="en">statistical hypothesis test</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A statistical hypothesis test data transformation is a data transformation that has objective statistical hypothesis test.</obo:IAO_0000115>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: James Malone</obo:IAO_0000119>
<rdfs:label xml:lang="en">statistical hypothesis test</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000674 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000674">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200181"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
<obo:IAO_0000111>center value</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A data item that is produced as the output of a center calculation data transformation and represents the center value of the input data.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: James Malone</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Monnie McGee</obo:IAO_0000117>
<obo:IAO_0000118>median</obo:IAO_0000118>
<rdfs:label xml:lang="en">center value</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000675 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000675">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200166"/>
<obo:IAO_0000111 xml:lang="en">statistical hypothesis test objective</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">is a data transformation objective where the aim is to estimate statistical significance with the aim of proving or disproving a hypothesis by means of some data transformation.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000117>Person:Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000118>hypothesis test objective</obo:IAO_0000118>
<obo:IAO_0000119>WEB: http://en.wikipedia.org/wiki/Statistical_hypothesis_testing</obo:IAO_0000119>
<rdfs:label xml:lang="en">statistical hypothesis test objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000676 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000676">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200182"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000100"/>
<obo:IAO_0000111>reduced dimension data set</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A data set that is produced as the output of a data vector reduction data transformation and consists of producing a data set which has fewer vectors than the input data set.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: James Malone</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Monnie McGee</obo:IAO_0000117>
<rdfs:label xml:lang="en">reduced dimension data set</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000678 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000678">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000639"/>
<owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/OBI_0000681"/>
<obo:IAO_0000111>portioning objective</obo:IAO_0000111>
<obo:IAO_0000112>The objective to obtain multiple aliquots of an enzyme preparation.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A material separation objective aiming to separate material into multiple portions, each of which contains a similar composition of the input material.</obo:IAO_0000115>
<rdfs:label>portioning objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000679 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000679">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200170"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
<obo:IAO_0000111>average value</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A data item that is produced as the output of an averaging data transformation and represents the average value of the input data.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: James Malone</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Monnie McGee</obo:IAO_0000117>
<obo:IAO_0000118>arithmetic mean</obo:IAO_0000118>
<rdfs:label xml:lang="en">average value</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000680 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000680">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0100051"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>whole organism preparation</obo:IAO_0000111>
<obo:IAO_0000112>putting a mouse in the blender. Not: putting a mouse on a scale</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A material entity which is the output of a process in which one or more whole organisms are prepared in a way to make it easier to study them, and in which the great majority of organismal parts are maintained</obo:IAO_0000115>
<obo:IAO_0000116>does this include injecting a dye to a patient to be able to visualize parts of his brain? If not, we should state that the components of the organism are substantially re-arranged.</obo:IAO_0000116>
<rdfs:label>whole organism preparation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000681 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000681">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000639"/>
<obo:IAO_0000111>separation into different composition objective</obo:IAO_0000111>
<obo:IAO_0000112>The objective to obtain cells contained in a sample of blood.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A material separation objective aiming to separate a material entity that has parts of different types, and end with at least one output that is a material with parts of fewer types (modulo impurities).</obo:IAO_0000115>
<obo:IAO_0000116>We should be using has the grain relations or concentrations to distinguish the portioning and other sub-objectives</obo:IAO_0000116>
<rdfs:label>separation into different composition objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000682 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000682">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_study result</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Study result is an information content entity that is a specified data output of a study.</obo:IAO_0000115>
<obo:IAO_0000119>GROUP: OBI</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000230"/>
<rdfs:label>obsolete_study result</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000684 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000684">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000005"/>
<obo:IAO_0000111>specimen collection objective</obo:IAO_0000111>
<obo:IAO_0000112>The objective to collect bits of excrement in the rainforest. The objective to obtain a blood sample from a patient.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A objective specification that is fulfilled by obtaining a material entity for potential use as an input upon which measurements or observations are performed.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">OBI recommends against subclassing this term in order to avoid further parallel hierarchies between this term and specimen collection process.</obo:IAO_0000116>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>Bjoern Peters</obo:IAO_0000119>
<rdfs:label>specimen collection objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000685 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000685">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000652"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0302729"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000686"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>creating a mixture of molecules in solution</obo:IAO_0000111>
<obo:IAO_0000112>The production of PBS</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">is a process with the objective to prepare a liquid solution of one or more chemicals at desired concentrations.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Helen Parkinson</obo:IAO_0000119>
<rdfs:label>creating a mixture of molecules in solution</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000686 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000686">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
<obo:IAO_0000111>material combination objective</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">is an objective to obtain an output material that contains several input materials.</obo:IAO_0000115>
<obo:IAO_0000117>PPPB branch</obo:IAO_0000117>
<obo:IAO_0000119>bp</obo:IAO_0000119>
<rdfs:label>material combination objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000687 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000687">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600064"/>
<obo:IAO_0000111>nucleotide overhang cloning</obo:IAO_0000111>
<obo:IAO_0000112>Cloning vectors are commercially available and supplied in linearized form with 3' dT overhangs</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Nucleotide overhang cloning is the process of inserting nucleic acid into a vector using nucleotide overhangs used to prevent self ligation</obo:IAO_0000115>
<obo:IAO_0000117>Helen Parkinson</obo:IAO_0000117>
<rdfs:label>nucleotide overhang cloning</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000688 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000688">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000715"/>
<obo:IAO_0000111>rodent care protocol</obo:IAO_0000111>
<obo:IAO_0000112>Keeping mice in the UCSD animals facility at 20 - 25 degrees celsius, in cages of 4 animals each and providing food twice daily.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A rodent care protocol is an animal protocol in which the animals being taken care of are rodents.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>Bjoern Peters</obo:IAO_0000119>
<rdfs:label>rodent care protocol</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000689 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000689">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400103"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
<owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/OBI_0000758"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>454 Genome Sequence 20</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 18946007.Pyrosequencing analysis of the oral microflora of healthy adults. Keijser BJ, Zaura E, Huse SM, van der Vossen JM, Schuren FH, Montijn RC, ten Cate JM, Crielaard W. J Dent Res. 2008 Nov;87(11):1016-20.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">is a DNA sequencer first manufactured by 454 Life Science Corporation in 2005, and enables pyrosequencing to be performed. It comprises both optics and fluidics subsystems, which are controlled by a computer subsystem. The fluidics subsystem ensures accurate reagent dispensing. It consists of a reagents cassette (which holds the reagent containers), a sipper manifold, pumps, valves, and debubblers. The fluidics subsystem flows the sequencing reagents across the wells of the PicoTiterPlate device, and moves the spent reagents from the PicoTiterPlate device to the waste receptacle. The optics subsystem consists of a CCD camera and a camera controller. The camera captures the light emitted in the wells of the PicoTiterPlate device during each step of the sequencing cycle, and sends the digital images to the computer subsystem for processing. The computer controls the other Sequencer subsystems, and processes the digital images sent by the camera to extract the DNA sequence information.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>GS 20</obo:IAO_0000118>
<rdfs:label>454 Genome Sequence 20</rdfs:label>
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<obo:IAO_0000111>immunoprecipitation</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 19419533. Arabidopsis RNA immunoprecipitation. Terzi LC, Simpson GG. Plant J. 2009 Jul;59(1):163-8.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">is a process which realizes a material separation objective by relying on antibodies to specifically binding to material entity</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>OBI plan and planned process branch</obo:IAO_0000119>
<rdfs:label>immunoprecipitation</rdfs:label>
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<obo:IAO_0000111>ABI 377 automated sequencer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">is a DNA sequencer which is manufactured by Applied Biosystems corporation (formerly Perkin-Elmer). It allows automated chain termination DNA sequencing. It has part polyacrylamide gel electrophoresis system and a laser -based detection system to detect fluorescence intensity emitted by the dyes attached to the dideoxyterminator nucleotides or to the primers.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>Applied Biosystems</obo:IAO_0000119>
<rdfs:label>ABI 377 automated sequencer</rdfs:label>
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<obo:IAO_0000115 xml:lang="en">a recombination enzyme based cloning is a recombinant vector cloning process that uses complementary nucleotide sequences in both the insert genetic material and the cloning vector with a recombination enzyme to directly create a recombinant vector</obo:IAO_0000115>
<rdfs:label>recombination enzyme based cloning</rdfs:label>
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<obo:IAO_0000111>MeDIP-seq assay</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 18612301. A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis. Down TA, Rakyan VK, Turner DJ, Flicek P, Li H, Kulesha E, Gr�_f S, Johnson N, Herrero J, Tomazou EM, Thorne NP, B�_ckdahl L, Herberth M, Howe KL, Jackson DK, Miretti MM, Marioni JC, Birney E, Hubbard TJ, Durbin R, Tavar�� S, Beck S. Nat Biotechnol. 2008 Jul;26(7):779-85.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A DNA methylation profiling assay that identifies methylated sites in genomic DNA and determines the methylation pattern that affect gene transcription using immunoprecipitation of methylated genomic DNA, creation of a library of corresponding DNA fragments (either single or paired-end fragments) and subsequent sequencing using parallelized sequencing methods.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>Methylated DNA immunoprecipitation sequencing assay</obo:IAO_0000118>
<obo:IAO_0000119>url:https://en.wikipedia.org/wiki/Methylated_DNA_immunoprecipitation</obo:IAO_0000119>
<rdfs:label>MeDIP-seq assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000694 -->
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<obo:IAO_0000111>animal feeding</obo:IAO_0000111>
<obo:IAO_0000112>giving crickets to a snake.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">animal feeding is a process in which animals are provided with food</obo:IAO_0000115>
<obo:IAO_0000116>In an investigation, this will typically be part of an animal care process</obo:IAO_0000116>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>branch derived</obo:IAO_0000119>
<rdfs:label>animal feeding</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000695 -->
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<obo:IAO_0000111>chain termination sequencing assay</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 271968. DNA sequencing with chain-terminating inhibitors.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A DNA sequencing assay which rely on the use of dideoxynucleotides used in 4 distinct sequencing reaction on the same DNA sample. The dideoxynucleotides, once incorporated in the complementary DNA strand being synthesized by the DNA polymerase prevent any further chain elongation. The newly generated sequences are resolved on a polyacrylamide gel using electrophoresis and labels (either fluorochrome or radioactivity) are used to determine the nucleotide present at a given position</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>Sanger sequencing</obo:IAO_0000118>
<obo:IAO_0000118>dye terminator sequencing</obo:IAO_0000118>
<obo:IAO_0000119>url:https://en.wikipedia.org/wiki/Sanger_sequencing</obo:IAO_0000119>
<rdfs:label>chain termination sequencing assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000696 -->
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<obo:IAO_0000111>AB SOLiD System</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 19336255. RNA-Seq-quantitative measurement of expression through massively parallel RNA-sequencing. Wilhelm BT, Landry JR. Methods. 2009 Jul;48(3):249-57.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">is a DNA sequencer which is manufactured by Applied Biosystems and which enable DNA sequencing by ligation</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>Applied Biosystems</obo:IAO_0000119>
<rdfs:label>AB SOLiD System</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000697 -->
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<obo:IAO_0000111>Helicos sequencing assay</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 18388294. Single-molecule DNA sequencing of a viral genome.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A DNA sequencing by synthesis assay that identifiies the sequnece of billions of DNA molecules immobilized to a surface using DNA polymerase and fluorescently labeled nucleotides added one at a time. The sequencing process does not require an amplification step and is typically able to produce reads of 25 base pair length.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>true single molecule sequencing</obo:IAO_0000118>
<obo:IAO_0000119>url:https://en.wikipedia.org/wiki/Helicos_single_molecule_fluorescent_sequencing</obo:IAO_0000119>
<rdfs:label>Helicos sequencing assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000698 -->
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<obo:IAO_0000111>obsolete_DNA ligase</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A DNA ligase is an enzyme that covalently joins two compatible pieces of DNA through the cleavage of an ATP molecule</obo:IAO_0000115>
<obo:IAO_0000117>Kevin Clancy, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000118>ligase</obo:IAO_0000118>
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<rdfs:label>obsolete_DNA ligase</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
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<obo:IAO_0000111>survival assessment assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures the occurrence of death events in one or more organisms over time</obo:IAO_0000115>
<rdfs:label>survival assessment assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000700 -->
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<obo:IAO_0000111>support vector machine</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A support vector machine is a data transformation with a class prediction objective based on the construction of a separating hyperplane that maximizes the margin between two data sets of vectors in n-dimensional space.</obo:IAO_0000115>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<obo:IAO_0000117>Ryan Brinkman</obo:IAO_0000117>
<obo:IAO_0000118>SVM</obo:IAO_0000118>
<obo:IAO_0000119>PERSON: Ryan Brinkman</obo:IAO_0000119>
<rdfs:label>support vector machine</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000701 -->
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<obo:IAO_0000111>self-organizing map</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A self-organizing map (SOM) is an artificial neural network with objective class discovery that uses a neighborhood function to preserve the topological properties of a dataset to produce low-dimensional (typically 2) discretized representation of the training data set. A set of artificial neurons learn to map points in an input space to coordinates in an output space. The input space can have different dimensions and topology from the output space, and the SOM will attempt to preserve these.</obo:IAO_0000115>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<obo:IAO_0000117>Ryan Brinkman</obo:IAO_0000117>
<obo:IAO_0000118>SOM</obo:IAO_0000118>
<obo:IAO_0000119>PERSON: Ryan Brinkman</obo:IAO_0000119>
<rdfs:label>self-organizing map</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000702 -->
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</owl:Restriction>
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<obo:IAO_0000111>454 Genome Sequencer FLX</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 18616967. The Genome Sequencer FLX System--longer reads, more applications, straight forward bioinformatics and more complete data sets. Droege M, Hill B. J Biotechnol. 2008 Aug 31;136(1-2):3-10.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">is a DNA sequencer which was first manufactured by 454 Life Science Corporation in 2008 and enables pyrosequencing to be performed. It comprises both optics and fluidics subsystems, which are controlled by a computer subsystem. The fluidics subsystem ensures accurate reagent dispensing. It consists of a reagents cassette (which holds the reagent containers), a sipper manifold, pumps, valves, and debubblers. The fluidics subsystem flows the sequencing reagents across the wells of the PicoTiterPlate device, and moves the spent reagents from the PicoTiterPlate device to the waste receptacle. The optics subsystem consists of a CCD camera and a camera controller. The camera captures the light emitted in the wells of the PicoTiterPlate device during each step of the sequencing cycle, and sends the digital images to the computer subsystem for processing. The computer controls the other Sequencer subsystems, and processes the digital images sent by the camera to extract the DNA sequence information. It has the ability to sequence 400-600 million base pairs per run with 400-500 base pair read lengths.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>454 GS FLX</obo:IAO_0000118>
<obo:IAO_0000118>GS-FLX</obo:IAO_0000118>
<obo:IAO_0000119>adapted from https://www.roche-applied-science.com/servlet/RCProductDisplay?langId=-1&storeId=10202&productId=3.8.8.1.1.3&catalogId=10202&krypto=mgV8a0Sdps6%2BCXU8IoddmzNEyGgjde9j8MOFCiMzRsduELeenAlVZ%2FE1QR%2BxLpzNlqMZPLRHqaI%3D&ddkey=https:RCProductDisplay</obo:IAO_0000119>
<rdfs:label>454 Genome Sequencer FLX</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000703 -->
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</owl:Restriction>
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<obo:IAO_0000111>Illumina Genome Analyzer II</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 19336255. RNA-Seq-quantitative measurement of expression through massively parallel RNA-sequencing. Wilhelm BT, Landry JR.Methods. 2009 Jul;48(3):249-57.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">is a DNA sequence which is manufactured by Illumina (Solexa) corporation. it support sequencing of single or paired end clone libraries relying on sequencing by synthesis technology</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>Illumina Corporation</obo:IAO_0000119>
<rdfs:label>Illumina Genome Analyzer II</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000704 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000704">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200166"/>
<obo:IAO_0000111>decision tree induction objective</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A decision tree induction objective is a data transformation objective in which a tree-like graph of edges and nodes is created and from which the selection of each branch requires that some type of logical decision is made.</obo:IAO_0000115>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<rdfs:label>decision tree induction objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000705 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000705">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600047"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
</owl:Restriction>
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</owl:Restriction>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/SO_0000104"/>
</owl:Restriction>
</owl:someValuesFrom>
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<obo:IAO_0000111>Edman degradation</obo:IAO_0000111>
<obo:IAO_0000112>Determination of the amino acid sequence of a peptide eluted from HLA-DRB1*04:01 to be VYPEVTVYPAKT.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A sequencing assay in which the amino acid sequence of input peptides or proteins is determined by iteratively cleaving of the amino-terminal (N-terminal) residue without disrupting the peptide bonds and identifying it by e.g. chromatography or electropheresis.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>Edman degradation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000706 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000706">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000723"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000696"/>
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</owl:Class>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000722"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000736"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/PR_000023089"/>
</owl:unionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>SOLiD sequencing assay</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 19119315. High-resolution analysis of the 5'-end transcriptome using a next generation DNA sequencer. Hashimoto S, Qu W, Ahsan B, Ogoshi K, Sasaki A, Nakatani Y, Lee Y, Ogawa M, Ametani A, Suzuki Y, Sugano S, Lee CC, Nutter RC, Morishita S, Matsushima K. PLoS One. 2009;4(1):e4108.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A DNA sequencing by ligation assay that identifies sequence information using primers to hybridize to the P1 adapter sequence within the library template, fluorescently labeled di-base probes to compete for ligation to the sequencing primer, multiple cycles of ligation, detection and cleavage to determine the eventual read length, following a series of ligation cycles, the extension product is removed and the template is reset with a primer complementary to the n-1 position for a second round of ligation cycles.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>url:https://en.wikipedia.org/wiki/ABI_Solid_Sequencing</obo:IAO_0000119>
<rdfs:label>SOLiD sequencing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000707 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000707">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000704"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200000"/>
<obo:IAO_0000111 xml:lang="en">decision tree building data transformation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A decision tree building data transformation is a data transformation that has objective decision tree induction.</obo:IAO_0000115>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: James Malone</obo:IAO_0000119>
<rdfs:label xml:lang="en">decision tree building data transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000708 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000708">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000059"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000715"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000029"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
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<obo:IAO_0000111>laboratory animal care</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a process that realizes an animal care protocol that specifies how animals are kept and maintained</obo:IAO_0000115>
<rdfs:label>laboratory animal care</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000709 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000709">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_4705"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000737"/>
<rdfs:subClassOf>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000411"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>yeast artificial chromosome vector</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a double-stranded DNA that was engineered to contain a yeast origin of replication, encodes for a selectable gene product, contains a cloning site, and has yeast telomerase sequences</obo:IAO_0000115>
<obo:IAO_0000116>this should be a child of 'chromosome' if we import that from another source</obo:IAO_0000116>
<obo:IAO_0000117>Kevin Clancy, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000118>YAC</obo:IAO_0000118>
<rdfs:label>yeast artificial chromosome vector</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000710 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000710">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400103"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
<owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/OBI_0000769"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>Li-Cor 4300 DNA Analysis System</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">is a DNA sequencer which is manufactured by Li-Cor corporation and enable automated chain termination based DNA sequencing</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>OBI and Li-Cor</obo:IAO_0000119>
<rdfs:label>Li-Cor 4300 DNA Analysis System</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000711 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000711">
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_16991"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_4705"/>
</owl:unionOf>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000164"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000722"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000736"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_1000029"/>
</owl:unionOf>
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</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>library preparation</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 19570239. Construction and analysis of cotton (Gossypium arboreum L.) drought-related cDNA library. Zhang L, Li FG, Liu CL, Zhang CJ, Zhang XY. BMC Res Notes. 2009 Jul 2;2:120.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">is a process which results in the creation of a library from fragments of DNA using cloning vectors or oligonucleotides with the role of adaptors.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>library construction</obo:IAO_0000118>
<rdfs:label>library preparation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000712 -->
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<rdfs:subClassOf>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000725"/>
</owl:Restriction>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000319"/>
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<!-- http://purl.obolibrary.org/obo/OBI_0000713 -->
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<obo:IAO_0000115 xml:lang="en">a software that provides access to more than 100 tools for gene expression analysis, proteomics, SNP analysis and common data processing tasks.</obo:IAO_0000115>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<obo:IAO_0000117>Person:Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000119>WEB: http://www.broadinstitute.org/cancer/software/genepattern/</obo:IAO_0000119>
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<obo:IAO_0000112>For example, if the nodes are cities, then the edges may have numerical values that correspond to the distances between the cities.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A construct that consists of many nodes connected with edges. The edges represent a relationship between the objects represented by the nodes. A graph can be equivalently represented as a matrix.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<obo:IAO_0000119>WEB: http://mitpress.mit.edu/books/FLAOH/cbnhtml/glossary-G.html</obo:IAO_0000119>
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<obo:IAO_0000111>animal care protocol</obo:IAO_0000111>
<obo:IAO_0000112>Keeping mice in the UCSD animals facility at 20 - 25 degrees celsius, in cages of 4 animals each and providing food twice daily.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An animal care protocol is a protocol which specifies the environment in which animals are being kept in captivity for research purposes</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>Bjoern Peters</obo:IAO_0000119>
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<!-- http://purl.obolibrary.org/obo/OBI_0000716 -->
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<obo:IAO_0000112>PMID: 19275939</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An assay in which chromatin is immunoprecipitated and subsequently analyzed using a DNA sequencing step to identify which parts of DNA are part of the isolated chromatin</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>chromatin immunoprecipitation sequencing assay</obo:IAO_0000118>
<obo:IAO_0000119>url:https://en.wikipedia.org/wiki/ChIP-sequencing</obo:IAO_0000119>
<rdfs:label>ChIP-seq assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000717 -->
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<obo:IAO_0000111>HeliScope Single Molecule Sequencer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">is a DNA sequencer manufacturer by Helicos Corporation to carry out Single Molecule sequencing using reversible termination chemistry</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
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<!-- http://purl.obolibrary.org/obo/OBI_0000718 -->
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<obo:IAO_0000111>pathogen role</obo:IAO_0000111>
<obo:IAO_0000112>Pathogen: An agent of disease. A disease producer. The term pathogen most commonly is used to refer to infectious organisms. These include bacteria (such as staph), viruses (such as HIV), and fungi (such as yeast). Less commonly, pathogen refers to a noninfectious agent of disease such as a chemical. http://www.medterms.com/script/main/art.asp?articlekey=6383</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">pathogen role is a role which inheres in an organism and realized in the process of disease course in the organism bearing host role caused by the organism bearing pathogen role</obo:IAO_0000115>
<obo:IAO_0000117>GROUP: Role Branch</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000232>6 April 2009: from the Vaccine Community</obo:IAO_0000232>
<rdfs:label>pathogen role</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000719 -->
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<obo:IAO_0000111>vaccine preparation</obo:IAO_0000111>
<obo:IAO_0000112>The production of B. pertussis vaccine.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A planned process with the objective to create a vaccine.</obo:IAO_0000115>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>vaccine production</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000720 -->
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<obo:IAO_0000111>immunologic adjuvant role</obo:IAO_0000111>
<obo:IAO_0000112>Adjuvants are pharmacological or immunological agents that modify the effect of other agents (e.g., drugs, vaccines) while having few if any direct effects when given by themselves. http://en.wikipedia.org/wiki/Adjuvant</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The role a material entity plays when it is co-administered with an immunogen in order to enhance the immune response to the immunogen.</obo:IAO_0000115>
<obo:IAO_0000116>11Feb09:Vaccine Ontology Definition: Adjuvant boosts immune response of a vaccine or antigen in the host.
the role 'adjuvant role' inheres in some 'material entity' and is realized by some 'immune response assay'.</obo:IAO_0000116>
<obo:IAO_0000117>GROUP: Role branch</obo:IAO_0000117>
<obo:IAO_0000119>Vaccine Ontology, Wikipedia, OBI</obo:IAO_0000119>
<obo:IAO_0000232>Renamed from adjuvent role, to be a more specific useage for immunology, tracker https://sourceforge.net/tracker/?func=detail&atid=886178&aid=2887909&group_id=177891</obo:IAO_0000232>
<rdfs:comment></rdfs:comment>
<rdfs:label>immunologic adjuvant role</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000721 -->
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<obo:IAO_0000111>glucose tolerance test</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 19527607</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures glucose clearance from blood over time by repeated glucose measurement in blood serum or plasma after the administration of a glucose bolus in-vivo. This assay can be used to evaluate the severity of insulin resistance or the efficiency of glucose clearance.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>NuGO OBI plan branch</obo:IAO_0000119>
<rdfs:label>glucose tolerance test</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000722 -->
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<obo:IAO_0000111>paired-end library</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 19339662. Next-generation DNA sequencing of paired-end tags (PET) for transcriptome and genome analyses. Genome Res. 2009 Apr;19(4):521-32. Fullwood MJ, Wei CL, Liu ET, Ruan Y.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">is a collection of short paired tags from the two ends of DNA fragments are extracted and covalently linked as ditag constructs</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>mate-paired library</obo:IAO_0000118>
<obo:IAO_0000118>paired-end tag (PET) library</obo:IAO_0000118>
<obo:IAO_0000119>adapted from information provided by Solid web site</obo:IAO_0000119>
<rdfs:label>paired-end library</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000723 -->
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<obo:IAO_0000111>DNA sequencing by ligation assay</obo:IAO_0000111>
<obo:IAO_0000112>ABI Solid Sequencing uses the ligation-based DNA sequencing technology (https://en.wikipedia.org/wiki/ABI_Solid_Sequencing).</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A DNA sequencing assay that performs chain extension during the sequencing reaction step using DNA ligase</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>url:https://en.wikipedia.org/wiki/Sequencing_by_ligation</obo:IAO_0000119>
<rdfs:label>DNA sequencing by ligation assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000724 -->
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<obo:IAO_0000111>Solexa sequencing assay</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 18987734</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A DNA sequencing by synthesis assay that identifies sequence information using DNA polymerase and reversible terminator, requiring immobilization of genomic DNA fragments onto a surface and a specific clonal amplification step known as bridge PCR. Reliance on a reversible terminator allows cycles of DNA chain extension by DNA polymerase and imaging without the need of electrophoretic separation of newly synthesized DNA fragment as with Sanger sequencing.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>reversible terminator sequencing</obo:IAO_0000118>
<obo:IAO_0000119>Solexa web site (SS_DNAsequencing.pdf document available on july 2009)</obo:IAO_0000119>
<rdfs:label>Solexa sequencing assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000725 -->
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<obo:IAO_0000111>host role</obo:IAO_0000111>
<obo:IAO_0000112>In biology, a host is an organism that harbors a virus or parasite, or a mutual or commensal symbiont, typically providing nourishment and shelter. http://en.wikipedia.org/wiki/Host_(biology) 30 March 09</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">host role is a role played by an organism and realized by providing nourishment, shelter or a means of reproduction to another organism within the organism playing the host role</obo:IAO_0000115>
<obo:IAO_0000116>30Mar09 virus reproducing inside a cell; bacteria causing a disease, host can be harmed or not. we want to avoid a cat sitting on my lap and an animal care technician; these are not examples or hosts; dental cares = on tooth, but part of outer layer of tooth, so covered by "within" in the definition</obo:IAO_0000116>
<obo:IAO_0000117>GROUP: Role Branch</obo:IAO_0000117>
<obo:IAO_0000119>30 Mar09 submitted by vaccine community</obo:IAO_0000119>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Host_(biology)</obo:IAO_0000119>
<rdfs:label>host role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000726 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000726">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200000"/>
<obo:IAO_0000111>peak matching</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Peak matching is a data transformation performed on a dataset of a graph of ordered data points (e.g. a spectrum) with the objective of pattern matching local maxima above a noise threshold</obo:IAO_0000115>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<obo:IAO_0000117>Ryan Brinkman</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Ryan Brinkman</obo:IAO_0000119>
<rdfs:label>peak matching</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000727 -->
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200178"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200172"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">k-nearest neighbors</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A k-nearest neighbors is a data transformation which achieves a class discovery or partitioning objective, in which an input data object with vector y is assigned to a class label based upon the k closest training data set points to y; where k is the largest value that class label is assigned.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000118>k-NN</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">PERSON: James Malone</obo:IAO_0000119>
<rdfs:label xml:lang="en">k-nearest neighbors</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000728 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000728">
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000694"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400171"/>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000059"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000688"/>
</owl:Restriction>
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<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9989"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9989"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>rodent care</obo:IAO_0000111>
<obo:IAO_0000112>keeping animal</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">rodent care is the process by which rodents are being provided with a controlled living environment while kept in captivity for the purpose of research.</obo:IAO_0000115>
<obo:IAO_0000117>PPPB branch</obo:IAO_0000117>
<obo:IAO_0000119>PPPB branch</obo:IAO_0000119>
<rdfs:label>rodent care</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000729 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000729">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000430"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000411"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000430"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000737"/>
<obo:IAO_0000111>cloning plasmid</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A cloning plasmid is a plasmid that was engineered to contain a bacterial origin of replication, encodes for a selectable gene product and contains a cloning site.</obo:IAO_0000115>
<obo:IAO_0000116>Note: 'cloning vector role' is really a function. Should be dealt with globally</obo:IAO_0000116>
<rdfs:label>cloning plasmid</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000730 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000730">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000734"/>
<rdfs:subClassOf>
<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000689"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000702"/>
</owl:unionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000689"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000702"/>
</owl:unionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>pyrosequencing assay</obo:IAO_0000111>
<obo:IAO_0000112>Pyrosequencing sheds light on DNA sequencing. PMID:1115661</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A DNA sequencing by synthesis assay which sequences a single strand of DNA by synthesizing the complementary strand along it, one base pair at a time, and detecting which base was actually added at each step. The template DNA is immobilized, and solutions of A, C, G, and T nucleotides are added and removed after the reaction, sequentially. Light is produced only when the nucleotide solution complements the first unpaired base of the template. The sequence of solutions which produce chemiluminescent signals allows the determination of the sequence of the template. ssDNA template is hybridized to a sequencing primer and incubated with the enzymes DNA polymerase, ATP sulfurylase, luciferase and apyrase, and with the substrates adenosine 5-prime phosphosulfate (APS) and luciferin.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>url:http://en.wikipedia.org/wiki/Pyrosequencing</obo:IAO_0000119>
<rdfs:label>pyrosequencing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000731 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000731">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600064"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<obo:IAO_0000111>recombinant vector</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A recombinant vector is created by a recombinant vector cloning process, and contains nucleic acids that can be amplified. It retains functions of the original cloning vector.</obo:IAO_0000115>
<rdfs:label>recombinant vector</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000732 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000732">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0003824"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>restriction enzyme</obo:IAO_0000111>
<obo:IAO_0000112>The enzyme EcoR1 cuts DNA at the canonical cleavage site CAATTG</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">an enzyme that has a specific target cleavage sites within nucleic acids</obo:IAO_0000115>
<obo:IAO_0000117>Kevin Clancy, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000232>5/22 Need to explore if there are GO / other classes exist that capture this. We need it now for cloning experiments</obo:IAO_0000232>
<rdfs:label>restriction enzyme</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000734 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000734">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000626"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0042575"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>DNA sequencing by synthesis assay</obo:IAO_0000111>
<obo:IAO_0000112>Roche-454 pyrosequencing and Illumina (Solexa) sequencing use synthesis-based method for DNA sequencing</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A DNA sequencing assay that relies on DNA polymerase activity to perform chain extension during the sequencing reaction step.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>url:https://www.illumina.com/technology/next-generation-sequencing/sequencing-technology.html</obo:IAO_0000119>
<rdfs:label>DNA sequencing by synthesis assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000735 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000735">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000457"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000248"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>NTP-2000</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a material consisting of 14.5% protein, 8.5% fat and 9.5% fiber produced to feed rodents</obo:IAO_0000115>
<obo:IAO_0000117>Jennifer Fostel, Bjoern Peters</obo:IAO_0000117>
<rdfs:label>NTP-2000</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000736 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000736">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<obo:IAO_0000111>single fragment library</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">is a collection of short tags from DNA fragments, are extracted and covalently linked as single tag constructs</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>fragment library</obo:IAO_0000118>
<rdfs:label>single fragment library</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000737 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000737">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000411"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33696"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110108"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>cloning vector</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A cloning vector is an engineered material that is used as an input material for a recombinant vector cloning process to carry inserted nucleic acids. It contains an origin of replication for a specific destination host organism, encodes for a selectable gene product and contains a cloning site.</obo:IAO_0000115>
<rdfs:label>cloning vector</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000738 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000738">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600064"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0302892"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000411"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000742"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000416"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000742"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>restriction enzyme based cloning</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">restriction enzyme based cloning is a recombinant vector cloning process that has as an input genetic material that was cleaved with restriction enzymes, and a cloning vector that was cleaved with complementary restriction enzymes. It uses ligase to chemically join the input genetic material and the cloning vector to create a recombinant vector.</obo:IAO_0000115>
<obo:IAO_0000117>Kevin Clancy, Bjoern Peters</obo:IAO_0000117>
<rdfs:label>restriction enzyme based cloning</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000739 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000739">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000673"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000175"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000675"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>Student's t-test</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Studen't t-test is a data transformation with the objective of a statistical hypothesis test in which the test statistic has a Student's t distribution if the null hypothesis is true. It is applied when the population is assumed to be normally distributed but the sample sizes are small enough that the statistic on which inference is based is not normally distributed because it relies on an uncertain estimate of standard deviation rather than on a precisely known value.</obo:IAO_0000115>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<obo:IAO_0000119>WEB: http://en.wikipedia.org/wiki/T-test</obo:IAO_0000119>
<rdfs:label>Student's t-test</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000740 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000740">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000112"/>
<obo:IAO_0000111>material sample role</obo:IAO_0000111>
<obo:IAO_0000112>a role borne by a portion of blood taken to represent all the blood in an organism; the role borne by a population of humans with HIV enrolled in a study taken to represent patients with HIV in general.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A material sample role is a specimen role borne by a material entity that is the output of a material sampling process.</obo:IAO_0000115>
<obo:IAO_0000116>7/13/09: Note that this is a relational role: between the sample taken and the 'sampled' material of which the sample is thought to be representative off.</obo:IAO_0000116>
<obo:IAO_0000233 rdf:resource="https://github.com/obi-ontology/obi/issues/1013"/>
<rdfs:label>material sample role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000741 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000741">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000648"/>
<obo:IAO_0000111>topologically preserved clustered data set</obo:IAO_0000111>
<obo:IAO_0000112>the output data set generated from a self-organizing map.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A clustered data set in which the topology, i.e. the spatial properties between data points, is preserved from the original input data from which it was derived.</obo:IAO_0000115>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: James Malone</obo:IAO_0000119>
<rdfs:label>topologically preserved clustered data set</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000742 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000742">
<owl:equivalentClass>
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<obo:IAO_0000111>nucleic acid restriction enzyme digest</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A nucleic acid digest is a material that is the output of a process in which nucleic acids are combined with a restriction enzyme resulting in digested fragments with defined ends based on the enzymes cleavage site</obo:IAO_0000115>
<obo:IAO_0000117>Kevin Clancy, Bjoern Peters</obo:IAO_0000117>
<rdfs:label>nucleic acid restriction enzyme digest</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000743 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000743">
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</owl:Restriction>
</owl:someValuesFrom>
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<obo:IAO_0000111>immune response assay</obo:IAO_0000111>
<obo:IAO_0000112>Measuring if a Hepacivirus C (HCV) infected patient has an antibody response to HCV core protein by ELISA.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An assay that determines information about an immune response</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>immune response assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000744 -->
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<obo:IAO_0000111>material sampling process</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A specimen gathering process with the objective to obtain a specimen that is representative of the input material entity</obo:IAO_0000115>
<obo:IAO_0000118>sample collection</obo:IAO_0000118>
<obo:IAO_0000118>sampling</obo:IAO_0000118>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1002</obo:IAO_0000233>
<rdfs:label>material sampling process</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000747 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000747">
<owl:equivalentClass>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000740"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0100051"/>
<obo:IAO_0000111>material sample</obo:IAO_0000111>
<obo:IAO_0000112>blood drawn from patient to measure his systemic glucose level. A population of humans with HIV enrolled in a study taken to represent patients with HIV in general.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A material entity that has the material sample role</obo:IAO_0000115>
<obo:IAO_0000117>OBI: workshop</obo:IAO_0000117>
<obo:IAO_0000118>sample</obo:IAO_0000118>
<obo:IAO_0000118>sample population</obo:IAO_0000118>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1013</obo:IAO_0000233>
<rdfs:label>material sample</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000748 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000748">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000626"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400103"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001051"/>
</owl:Restriction>
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</owl:Class>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_32875"/>
</owl:Restriction>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003368"/>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
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<rdfs:subClassOf>
<owl:Restriction>
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</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000109"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001573"/>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001234"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>bisulfite sequencing assay</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 19581485. High definition profiling of mammalian DNA methylation by array capture and single molecule bisulfite sequencing. Hodges E, Smith A, Kendall J, Xuan Z, Ravi K, Rooks M, Zhang M, Ye K, Battacharjee A, Brizuela L, McCombie WR, Wigler M, Hannon GJ, Hicks J.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A DNA methylation profiling assay which determines the methylation status of genomic DNA using DNA sequencing techniques preceded by a bisulfite based chemical modification of genomic DNA at CpG island location.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000117>Sagar Jain</obo:IAO_0000117>
<obo:IAO_0000119>url:https://en.wikipedia.org/wiki/Bisulfite_sequencing</obo:IAO_0000119>
<rdfs:label>bisulfite sequencing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000749 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000749">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000707"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000704"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">CART</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A CART (classification and regression trees) is a data transformation method for producing a classification or regression model with a tree-based structure.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000118>classification and regression trees</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">BOOK: David J. Hand, Heikki Mannila and Padhraic Smyth (2001) Principles of Data Mining.</obo:IAO_0000119>
<rdfs:label xml:lang="en">CART</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000750 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000750">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>independent variable specification</obo:IAO_0000111>
<obo:IAO_0000112>In a study in which gene expression is measured in patients between 8 month to 4 years old that have mild or severe malaria and in which the hypothesis is that gene expression in that age group is a function of disease status, disease status is the independent variable.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">a directive information entity that is part of a study design. Independent variables are entities whose values are selected to determine its relationship to an observed phenomenon (the dependent variable). In such an experiment, an attempt is made to find evidence that the values of the independent variable determine the values of the dependent variable (that which is being measured). The independent variable can be changed as required, and its values do not represent a problem requiring explanation in an analysis, but are taken simply as given. The dependent variable on the other hand, usually cannot be directly controlled</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">2/2/2009 Original definition - In the design of experiments, independent variables are those whose values are controlled or selected by the person experimenting (experimenter) to determine its relationship to an observed phenomenon (the dependent variable). In such an experiment, an attempt is made to find evidence that the values of the independent variable determine the values of the dependent variable (that which is being measured). The independent variable can be changed as required, and its values do not represent a problem requiring explanation in an analysis, but are taken simply as given. The dependent variable on the other hand, usually cannot be directly controlled.</obo:IAO_0000116>
<obo:IAO_0000116>In the Philly 2013 workshop the label was chosen to distinguish it from "dependent variable" as used in statistical modelling. See: http://en.wikipedia.org/wiki/Statistical_modeling</obo:IAO_0000116>
<obo:IAO_0000117>PERSON: Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000118>experimental factor</obo:IAO_0000118>
<obo:IAO_0000118>independent variable</obo:IAO_0000118>
<obo:IAO_0000119>Web: http://en.wikipedia.org/wiki/Dependent_and_independent_variables</obo:IAO_0000119>
<obo:IAO_0000232>2009-03-16: work has been done on this term during during the OBI workshop winter 2009 and the current definition was considered acceptable for use in OBI. If there is a need to modify thisdefinition please notify OBI.</obo:IAO_0000232>
<obo:OBI_0001847>study factor</obo:OBI_0001847>
<rdfs:label xml:lang="en">study design independent variable</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000751 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000751">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>dependent variable specification</obo:IAO_0000111>
<obo:IAO_0000112>In a study in which gene expression is measured in patients between 8 month to 4 years old that have mild or severe malaria and in which the hypothesis is that gene expression in that age group is a function of disease status, the gene expression is the dependent variable.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">dependent variable specification is part of a study design. The dependent variable is the event studied and expected to change when the independent variable varies.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">2/2/2009 In the design of experiments, independent variables are those whose values are controlled or selected by the person experimenting (experimenter) to determine its relationship to an observed phenomenon (the dependent variable). In such an experiment, an attempt is made to find evidence that the values of the independent variable determine the values of the dependent variable (that which is being measured). The independent variable can be changed as required, and its values do not represent a problem requiring explanation in an analysis, but are taken simply as given. The dependent variable on the other hand, usually cannot be directly controlled.</obo:IAO_0000116>
<obo:IAO_0000116>In the Philly 2013 workshop the label was chosen to distinguish it from "dependent variable" as used in statistical modelling. See: http://en.wikipedia.org/wiki/Statistical_modeling</obo:IAO_0000116>
<obo:IAO_0000117>PERSON: Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000118>dependent variable</obo:IAO_0000118>
<obo:IAO_0000119>WEB: http://en.wikipedia.org/wiki/Dependent_and_independent_variables</obo:IAO_0000119>
<obo:IAO_0000232>2009-03-16: work has been done on this term during during the OBI workshop winter 2009 and the current definition was considered acceptable for use in OBI. If there is a need to modify thisdefinition please notify OBI.</obo:IAO_0000232>
<rdfs:label xml:lang="en">study design dependent variable</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000784 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000784">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000836"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002219"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_32142"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>anticoagulant-containing test tube</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A 'blue top' test tube that contains anticoagulant for storing blood specimens'</obo:IAO_0000115>
<obo:IAO_0000117>Person:Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000232>2009/09/28 Alan Ruttenberg. Fucoidan-use-case</obo:IAO_0000232>
<rdfs:label>anticoagulant-containing test tube</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000785 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000785">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>controlled variable specification</obo:IAO_0000111>
<obo:IAO_0000112>In a study in which gene expression is measured in patients between 8 month to 4 years old that have mild or severe malaria and in which the hypothesis is that gene expression in that age group is a function of disease status, age is a controlled variable.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">Controlled variable specification is a part of a study design. They are the entities that could vary, but are kept constant to prevent their influence on the effect of the independent variable on the dependent.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">2/2/2009 Original definition: Controlled variables are also important to identify in experiments. They are the variables that are kept constant to prevent their influence on the effect of the independent variable on the dependent. Every experiment has a controlling variable, and it is necessary to not change it, or the results of the experiment won't be valid</obo:IAO_0000116>
<obo:IAO_0000116>In the Philly 2013 workshop the label was chosen to distinguish it from "controlled variable" as used in statistical modelling</obo:IAO_0000116>
<obo:IAO_0000117>PERSON: Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000118>controlled variable</obo:IAO_0000118>
<obo:IAO_0000119>WEB: http://en.wikipedia.org/wiki/Control_variable</obo:IAO_0000119>
<obo:IAO_0000232>2009-03-16: work has been done on this term during during the OBI workshop winter 2009 and the current definition was considered acceptable for use in OBI. If there is a need to modify thisdefinition please notify OBI.</obo:IAO_0000232>
<rdfs:label xml:lang="en">study design controlled variable</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000787 -->
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<obo:IAO_0000111>human antithrombin-III in blood assay</obo:IAO_0000111>
<obo:IAO_0000112>PMID:19696660#The antithrombin-III (AT-III) was determined using a Berichrom(r) Antithrombin-III (A) kit.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures the amount of antithrombin III in blood.</obo:IAO_0000115>
<obo:IAO_0000117>Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000118>AT-III assay</obo:IAO_0000118>
<obo:IAO_0000119>url:http://www.muschealth.com/lab/content.aspx?id=150006@2009/08/06</obo:IAO_0000119>
<rdfs:label>human antithrombin-III in blood assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000788 -->
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<obo:IAO_0000111>fluorescently labeled MHC multimer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A complex of two or more linked MHC molecules including a fluorescent label that can be loaded with a ligand, and is used in flow cytometry assay to bind to T cell receptors of T cells specific for the ligand</obo:IAO_0000115>
<rdfs:label>fluorescently labeled MHC multimer</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000789 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000789">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
<obo:IAO_0000111>survival rate</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A measurement data that represents the percentage of people or animals in a study or treatment group who are alive for a given period of time after diagnosis or initiation of monitoring.</obo:IAO_0000115>
<obo:IAO_0000117>Oliver He</obo:IAO_0000117>
<obo:IAO_0000119>adapted from wikipedia
http://en.wikipedia.org/wiki/Survival_rate</obo:IAO_0000119>
<rdfs:label>survival rate</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000790 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600064"/>
<obo:IAO_0000111>recombinant BAC cloning</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Recombinant BAC cloning is a process with the objective to insert genetic material into an F plasmid based bacterial artificial chromosome for future replication of the inserted material</obo:IAO_0000115>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Bacterial_artificial_chromosome</obo:IAO_0000119>
<rdfs:label>recombinant BAC cloning</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000791 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000791">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200186"/>
<obo:IAO_0000111>multiple testing correction objective</obo:IAO_0000111>
<obo:IAO_0000112>Application of the Bonferroni correction</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A multiple testing correction objectives is a data transformation objective where the aim is to correct for a set of statistical inferences considered simultaneously</obo:IAO_0000115>
<obo:IAO_0000118>multiple comparison correction objective</obo:IAO_0000118>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Multiple_Testing_Correction</obo:IAO_0000119>
<rdfs:label>multiple testing correction objective</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000792 -->
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200188"/>
</owl:Restriction>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200171"/>
<obo:IAO_0000111>statistical model validation</obo:IAO_0000111>
<obo:IAO_0000112>Using the expression levels of 20 proteins to predict whether a cancer patient will respond to a drug. A practical goal would be to determine which subset of the 20 features should be used to produce the best predictive model. - wikipedia</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A data transformation which assesses how the results of a statistical analysis will generalize to an independent data set.</obo:IAO_0000115>
<obo:IAO_0000117>Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Cross-validation_%28statistics%29</obo:IAO_0000119>
<rdfs:label>statistical model validation</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000793 -->
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</owl:unionOf>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000822"/>
<obo:IAO_0000111>double blind study execution</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A double blind study execution is defined as any study execution in which neither the subjects nor the investigators are informed of which study arm the subjects are part of during the portion of the trial when the subjects are being treated</obo:IAO_0000115>
<obo:IAO_0000117>Person:Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000119>http://clinicaltrials.gov/ct2/info/glossary#double</obo:IAO_0000119>
<obo:IAO_0000232>2009/09/28 Alan Ruttenberg. Fucoidan-use-case</obo:IAO_0000232>
<rdfs:label>double blind study execution</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000794 -->
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<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete transcription factor binding site</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000002"/>
<obo:IAO_0000119>SO:0000235</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<obo:IAO_0000232>PLace_holder for sequence ontology term</obo:IAO_0000232>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1553</obo:IAO_0000233>
<obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/SO_0000235"/>
<rdfs:label>obsolete transcription factor binding site</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
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<!-- http://purl.obolibrary.org/obo/OBI_0000795 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000795">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
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<obo:IAO_0000111>glucometer</obo:IAO_0000111>
<obo:IAO_0000112>Diabetic patients use glucometers to determine their glucose levels</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A measurement device with the function to measure and record the level/amount of glucose in a blood sample</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000117>PERSON:Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000118>glucose meter</obo:IAO_0000118>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Glucose_meter</obo:IAO_0000119>
<rdfs:label>glucometer</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000796 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000681"/>
<obo:IAO_0000111>purification objective</obo:IAO_0000111>
<obo:IAO_0000112>the objective to obtain a pure fraction of a specific peptide when running an HPLC on a crude synthesis of peptides.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The objective to separate a material entity into different compositions of which one or more have are purified fractions that contain higher concentration of a desired component, while others contain impurities and are not of interest</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000118>isolation objective</obo:IAO_0000118>
<obo:IAO_0000119>BP</obo:IAO_0000119>
<obo:IAO_0000232>10/14/09, BP: This should be linked to the 'purified' 'currently conferred quality</obo:IAO_0000232>
<rdfs:label>purification objective</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000797 -->
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<obo:IAO_0000111>obsolete_primary structure of protein</obo:IAO_0000111>
<obo:IAO_0000112>SIINFEKL' is the primary structure of a peptide</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">The primary structure of a protein that is completely defined by the set of its amino acid residue parts and the linear order induced by the peptide bonds that hold them together</obo:IAO_0000115>
<obo:IAO_0000117>Person:Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<rdfs:label>obsolete_primary structure of protein</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
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<!-- http://purl.obolibrary.org/obo/OBI_0000798 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000798">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000111>capsule shell</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a small rounded gelatinous container</obo:IAO_0000115>
<obo:IAO_0000117>Person:Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000119>http://www.golovchenko.org/cgi-bin/wnsearch?q=capsule#2n</obo:IAO_0000119>
<obo:IAO_0000232>2009/09/28 Alan Ruttenberg. Fucoidan-use-case</obo:IAO_0000232>
<rdfs:label>capsule shell</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000799 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000799">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600064"/>
<obo:IAO_0000111>recombinant phage cloning</obo:IAO_0000111>
<obo:IAO_0000112>Insert selection by BamHI methyltransferase protection in P1 phage-based cloning</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Recombinant phage cloning is the process of using a phage plus some insert nucleic acid for the purposes of amplification of the insert material achieved by phage assembly in vitro.</obo:IAO_0000115>
<obo:IAO_0000117>Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000119>http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=mcb.section.1611</obo:IAO_0000119>
<rdfs:label>recombinant phage cloning</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000800 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000800">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
</owl:Restriction>
</rdfs:subClassOf>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>cross linking</obo:IAO_0000111>
<obo:IAO_0000112>cross linking can be used as a probe to link proteins together, to check protein protein interactions</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A process in which bonds are created that link one polymer to another</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Cross-link</obo:IAO_0000119>
<rdfs:label>cross linking</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000801 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000801">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
<obo:IAO_0000111>spike train datum</obo:IAO_0000111>
<obo:IAO_0000112>Measurement of temporal regularity of spike train responses in auditory nerve fibers of the green treefrog</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A measurement datum which represents information about an ordered series of action potentials in an organism's CNS measured over time.</obo:IAO_0000115>
<obo:IAO_0000116>needs more work to see exactly what the data set looks like - HP</obo:IAO_0000116>
<obo:IAO_0000117>Helen Parkinson, Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000118>spike train measurement</obo:IAO_0000118>
<obo:IAO_0000119>Jessica Turner, NIF</obo:IAO_0000119>
<rdfs:label>spike train datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000802 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000802">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<rdfs:subClassOf>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000032"/>
</owl:Restriction>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0007596"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>prothrombin time assay</obo:IAO_0000111>
<obo:IAO_0000112>PMID:19696660#The prothrombin time (PT) was quantitatively determined using RecombiPlasTin (Instrumentation Laboratory Company, Lexington, Massachusetts, USA).</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures the prothrombin ratio, which is the prothrombin time for a patient, divided by the result for control plasma. Most commonly the test is preformed using blood plasma. Blood is drawn into a test tube containing liquid citrate, which acts as an anticoagulant. An excess of calcium is added to enable the blood to clot again.Tissue factor (also known as factor III or thromboplastin) is added, and the time the sample takes to clot is measured optically as the prothrombin time, which is compared to a control sample.</obo:IAO_0000115>
<obo:IAO_0000117>Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000119>url:http://en.wikipedia.org/wiki/Prothrombin_time@2009/10/06</obo:IAO_0000119>
<rdfs:label>prothrombin time assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000803 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000803">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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<owl:Class>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_33696"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/PR_000000001"/>
</owl:unionOf>
</owl:Class>
</owl:someValuesFrom>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>denaturing</obo:IAO_0000111>
<obo:IAO_0000112>Denaturing DNA in alcohol</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Is a process in which the tertiary or secondary structure of a polymer is disrupted</obo:IAO_0000115>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Denaturation_%28biochemistry%29</obo:IAO_0000119>
<rdfs:label>denaturing</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000804 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000804">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
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<obo:IAO_0000111>informing investigator of subject study arm</obo:IAO_0000111>
<obo:IAO_0000112>Informing the investigator whether a patient is receiving a placebo or a treatment with an investigational compound.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A planned process with the objective to make the investigator aware of which study arm a patient is participating in.</obo:IAO_0000115>
<obo:IAO_0000116>09/28/2009 Alan Ruttenberg. This and the class informing-subject-of-study-arm are defined in order to solve the question of how to represent single and double blind experiments. To represent the aspect of double blinding pertaining to investigators, we say that the study execution doesn't include any processes of this sort</obo:IAO_0000116>
<obo:IAO_0000117>Person:Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000232>2009/09/28 Alan Ruttenberg. Fucoidan-use-case</obo:IAO_0000232>
<rdfs:label>informing investigator of subject study arm</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000805 -->
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<obo:IAO_0000111>antithrombin-III berichrome assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An antithrombin-III (AT-III) assay in which exogenous bovine thrombin and heparin are added to test plasma to form a thrombin-heparin-AT complex. The residual thrombin not bound then hydrolyzes the p-nitroalanine substrate to produce a yellow color, which is read at 405 nm. The intensity of color produced is inversely proportional to the AT present. A calibration is done with standard human plasma reagent and results for a given specimen are reported as a percentage relative to the standard</obo:IAO_0000115>
<obo:IAO_0000118>AT-III assay</obo:IAO_0000118>
<obo:IAO_0000119>url:http://www.clinchem.org/cgi/content/full/43/9/1783@2009/08/06</obo:IAO_0000119>
<rdfs:label>antithrombin-III berichrome assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000806 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000806">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000005"/>
<obo:IAO_0000111>material maintenance objective</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An objective specification maintains some or all of the qualities of a material over time.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Bjoern Peters</obo:IAO_0000119>
<rdfs:label>material maintenance objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000807 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000807">
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<obo:IAO_0000111>presentation of stimulus</obo:IAO_0000111>
<obo:IAO_0000112>The presentation of a flashing light to a monkey during reward training</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A planned process with the objective to expose an organism to a stimulus.</obo:IAO_0000115>
<obo:IAO_0000117>Helen Parkinson, Jessica Turner, Dirk Derom</obo:IAO_0000117>
<obo:IAO_0000118>stimulation of organism</obo:IAO_0000118>
<obo:IAO_0000119>Helen Parkinson, Jessica Turner, Dirk Derom</obo:IAO_0000119>
<rdfs:label>presentation of stimulus</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000808 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000808">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000032"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0007596"/>
</owl:Restriction>
</owl:someValuesFrom>
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<obo:IAO_0000111>spectrolyse heparin antifactor-Xa assay</obo:IAO_0000111>
<obo:IAO_0000112>PMID:19696660#Antifactor-Xa (anti-Xa) was determined using spectrolyse heparin (Xa) (Trinity Biotech plc, Bray, County Wicklow, Ireland).</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that quantitatively measures heparin in human plasma using Factor Xa and Antithrombin III in excess, where the rate of Factor Xa inhibition is directly proportional to the heparin concentration. The residual Factor Xa activity, measured with a Factor Xa-specific chromogenic substrate, is inversely proportional to the heparin concentration.</obo:IAO_0000115>
<obo:IAO_0000117>Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000119>url:http://www.kordia.nl/en/product/hemostasis/specialty_kits__reagens/598/spectrolyse_heparin_anti_xa@2009/08/06</obo:IAO_0000119>
<rdfs:label>spectrolyse heparin antifactor-Xa assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000809 -->
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<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_16991"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600058"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16991"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<obo:IAO_0000111>amplified DNA</obo:IAO_0000111>
<obo:IAO_0000112>Amplied DNA created by PCR</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">DNA that has been produced in an enzymatic amplification process</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000119>Alan Ruttenberg</obo:IAO_0000119>
<rdfs:label>amplified DNA</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000810 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000810">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000202"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>informed consent process</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A planned process with the objective to inform a person or their legal representative of legally and ethically relevant facts about a process that the person in question is asked to participate in, and which results in a documented decision as to whether the person in question will participate.</obo:IAO_0000115>
<obo:IAO_0000116>09/28/2009 Alan Ruttenberg: This is made a subclass of the higher level processual entity in BFO because I don't want to take a stand on whether it is a process aggregate. Analogous to the situation with Material entity.</obo:IAO_0000116>
<obo:IAO_0000117>Person:Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000119>http://clinicaltrials.gov/ct2/info/glossary#informed</obo:IAO_0000119>
<obo:IAO_0000232>2009/09/28 Alan Ruttenberg. Fucoidan-use-case</obo:IAO_0000232>
<rdfs:label>informed consent process</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000811 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000811">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000058"/>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16991"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/SO_0000001"/>
<obo:IAO_0000111>primary structure of DNA macromolecule</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a quality of a DNA molecule that inheres in its bearer due to the order of its DNA nucleotide residues.</obo:IAO_0000115>
<obo:IAO_0000116>placeholder for SO</obo:IAO_0000116>
<obo:IAO_0000117>BP et al</obo:IAO_0000117>
<rdfs:label>primary structure of DNA macromolecule</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000812 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000812">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000454"/>
<obo:IAO_0000111>measuring neural activity in the caudate nucleus assay</obo:IAO_0000111>
<obo:IAO_0000112>An SU micro-electrode was used to measure neural activity in the form of spike trains in the caudate nucleus of monkeys in response to a flashing light stimulus</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures neural activity in the caudate nucleus</obo:IAO_0000115>
<obo:IAO_0000117>Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000119>Dirk Derom, OBI</obo:IAO_0000119>
<obo:IAO_0000119>Jessica Turner, NIF</obo:IAO_0000119>
<rdfs:label>measuring neural activity in the caudate nucleus assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000813 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000813">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000097"/>
<obo:IAO_0000111>to be treated with active ingredient role</obo:IAO_0000111>
<obo:IAO_0000112>Role of a patient in a group treated with an active substance in a clinical trial</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A study subject role which begins to exist when a subject is assigned to be one of those who will receive active ingredient, and is realized in a study execution in which they receive the active ingredient</obo:IAO_0000115>
<obo:IAO_0000117>Person:Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Helen Parkinson</obo:IAO_0000119>
<obo:IAO_0000232>2009/09/28 Alan Ruttenberg. Fucoidan-use-case</obo:IAO_0000232>
<rdfs:label>to be treated with active ingredient role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000814 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000814">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000111>guar gum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Guar gum, also called guaran, is a galactomannan. It is primarily the ground endosperm of guar beans. The guar seeds are dehusked, milled and screened to obtain the guar gum.[1] It is typically produced as a free flowing, pale, off-white colored, coarse to fine ground powder.</obo:IAO_0000115>
<obo:IAO_0000117>Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Guar_gum</obo:IAO_0000119>
<rdfs:label>guar gum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000815 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000815">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<obo:IAO_0000111>Berichrom(r) Antithrombin III (A) Kit</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">For the chromogenic determination of antithrombin III. Autoanalyzer method for undiluted samples. For the quantitative chromogenic determination of the functional activity of antithrombin III in plasma on autoanalyzers for the diagnosis of diminished AT III synthesis, increased consumption, and for monitoring substitution therapy. Berichrom(r) Antithrombin III (A) is used for the rapid determination of the physiologically active antithrombin III and permits the diagnosis of congenital and acquired antithrombin III deficiency, a condition frequently associated with an increased risk of thrombosis. Acquired antithrombin III deficiencies frequently occur due to consumption following major operations or due to disseminated intravascular coagulation (DIC) in cases of septicaemia, nephroses, liver parenchymal damage (hepatitis, drug intoxication, alcoholism) and estrogen-containing contraceptives. The test permits early detection of patients at increased risk for thrombosis. Kit contains: 6 x for 5.0 mL Thrombin (bovine), 3 x for 3.0 mL Substrate Reagent, 1 x 30.0 mL Buffer Solution</obo:IAO_0000115>
<obo:IAO_0000117>Person:Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000119>WEB:http://www.dadebehring.com/edbna2/ebusiness/products/productDetail.jsp?sDiscipline=Hemostasis&FirstLevelOID=-13075&sCategory_Name=BCS&SecondLevelOID=-13895&ThirdLevelOID=-13904&selectedProductType=H-Assays+-+non+US&sProductName=OWWR15&PROD_OID=44198@2009/08/06</obo:IAO_0000119>
<obo:IAO_0000232>2009/09/28 Alan Ruttenberg. Fucoidan-use-case</obo:IAO_0000232>
<rdfs:label>Berichrom(r) Antithrombin III (A) Kit</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000816 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000816">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>micro electrode</obo:IAO_0000111>
<obo:IAO_0000112>A micro-electrode recording device used to record extracellular action potentialsin monkey caudate nucleus</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An electrode of very fine caliber consisting usually of a fine wire or a glass tube of capillary diameter drawn to a fine point and filled with saline or a metal used in physiological experiments to stimulate or record action currents of extracellular or intracellular origin in the nervous system.</obo:IAO_0000115>
<obo:IAO_0000117>Helen Parkinson, Jessica Turner, Dirk Derom</obo:IAO_0000117>
<obo:IAO_0000118>micro electrode measuring device</obo:IAO_0000118>
<obo:IAO_0000119>Jessica Turner, Dirk Derom</obo:IAO_0000119>
<rdfs:label>micro electrode</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000817 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000817">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<obo:IAO_0000111>fucoidan</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Fucoidan is a sulfated polysaccharide (MW: average 20,000) found mainly in various species of brown seaweed such as kombu, limu moui,bladderwrack, wakame, mozuku, and hijiki (variant forms of fucoidan have also been found in animal species, including the sea cucumber).</obo:IAO_0000115>
<obo:IAO_0000117>Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Fucoidan</obo:IAO_0000119>
<rdfs:label>fucoidan</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000818 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000818">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>calibration</obo:IAO_0000111>
<obo:IAO_0000112>the process of using pH buffer adjust a pH meter</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A planned process with the objective to establish the relationship between data produced by a measurement device and physical qualities. This is done by using the measurement device under defined conditions, and either tuning it to adjust the measured output, or record the output and use it as a reference in future measurements.</obo:IAO_0000115>
<obo:IAO_0000117>GROUP: OBI Philly workshop</obo:IAO_0000117>
<obo:IAO_0000119>WEB:http://en.wikipedia.org/wiki/calibration</obo:IAO_0000119>
<rdfs:label>calibration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000819 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000819">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0302893"/>
<rdfs:subClassOf>
<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100017"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000784"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002219"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100017"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>anticoagulant tube storage of blood specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Storage of a blood specimen in a tube with anticoagulant</obo:IAO_0000115>
<obo:IAO_0000117>Person:Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000232>2009/09/28 Alan Ruttenberg. Fucoidan-use-case</obo:IAO_0000232>
<rdfs:label>anticoagulant tube storage of blood specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000820 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000820">
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000655"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100016"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000416"/>
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<obo:IAO_0000111>activated partial thromboplastin time assay</obo:IAO_0000111>
<obo:IAO_0000112>The activated partial thromboplastin time (aPTT) was determined using Dade Actin FSL activated PTT reagent (PMID:19696660)</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that evaluates blood coagulation by measuring the time required for the appearance of fibrin strands following the mixing blood or plasma with phospholipid platelet substitute (e.g., crude cephalins, soybean phosphatides). It is a test of the intrinsic pathway (factors VIII, IX, XI, and XII) and the common pathway (fibrinogen, prothrombin, factors V and X) of blood coaguation . It is used as a screening test and to monitor heparin therapy.</obo:IAO_0000115>
<obo:IAO_0000116>There is also the 'partial thromboplastin assay', which some people use synonymously to aPPT, but historically was done slightly differently (without adding a coagulant).</obo:IAO_0000116>
<obo:IAO_0000117>Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000117>OBI call</obo:IAO_0000117>
<obo:IAO_0000118>aPTT assay</obo:IAO_0000118>
<obo:IAO_0000119>url:http://www.ebi.ac.uk/ols/ontologies/efo/terms?short_form=EFO_0004310</obo:IAO_0000119>
<rdfs:label>activated partial thromboplastin time assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000821 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000821">
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000798"/>
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</rdfs:subClassOf>
<obo:IAO_0000111>filled capsule</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pill in the form of a small rounded gelatinous container with medicine inside.</obo:IAO_0000115>
<obo:IAO_0000117>Person:Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000119>http://www.golovchenko.org/cgi-bin/wnsearch?q=capsule#2n</obo:IAO_0000119>
<obo:IAO_0000232>2009/09/28 Alan Ruttenberg. Fucoidan-use-case</obo:IAO_0000232>
<rdfs:label>filled capsule</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000822 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000822">
<owl:equivalentClass>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000826"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:allValuesFrom>
<owl:Class>
<owl:complementOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000842"/>
</owl:Class>
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</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000826"/>
<obo:IAO_0000111>single blind study execution</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A single blind study execution is defined as any study execution in which the subjects are not informed of which study arm they are part of during the portion of the trial when the subjects are being treated</obo:IAO_0000115>
<obo:IAO_0000117>Person:Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000119>http://clinicaltrials.gov/ct2/info/glossary#single</obo:IAO_0000119>
<obo:IAO_0000232>2009/09/28 Alan Ruttenberg. Fucoidan-use-case</obo:IAO_0000232>
<rdfs:label>single blind study execution</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000823 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000823">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000032"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0007596"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>thrombin time assay</obo:IAO_0000111>
<obo:IAO_0000112>PMID:19696660#The thrombin time was determined using thromboclotin assay kit.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures the time between the addition of the thrombin and the clot formation in plasma.</obo:IAO_0000115>
<obo:IAO_0000117>Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000119>url:http://en.wikipedia.org/wiki/Thrombin_time@2009/10/06</obo:IAO_0000119>
<rdfs:label>thrombin time assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000824 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000824">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600064"/>
<obo:IAO_0000111>recombinant YAC cloning</obo:IAO_0000111>
<obo:IAO_0000112>Isolation of a YAC clone covering a cluster of nine S100 genes on human chromosome 1q21</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Recombinant YAC cloning is a process with the objective to insert genetic material into a yeast artificial chromosome vector for future replication of the inserted material</obo:IAO_0000115>
<obo:IAO_0000117>Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000119>http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=mcb.section.1611</obo:IAO_0000119>
<rdfs:label>recombinant YAC cloning</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000825 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000825">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000097"/>
<obo:IAO_0000111>to be treated with placebo role</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study subject role which begins to exist when a subject is assigned to be one of those who will receive a placebo, and realized in a study execution in which they receive the placebo</obo:IAO_0000115>
<obo:IAO_0000117>Person:Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000232>2009/09/28 Alan Ruttenberg. Fucoidan-use-case</obo:IAO_0000232>
<rdfs:label>to be treated with placebo role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000826 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000826">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000471"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>treatment portion of study execution</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A planned process, part of a study design execution, during which the treatment of subjects is ongoing</obo:IAO_0000115>
<obo:IAO_0000116>09/28/2009 Alan Ruttenberg. Needed because we have to have a process to scope blinding over</obo:IAO_0000116>
<obo:IAO_0000117>Person:Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000232>2009/09/28 Alan Ruttenberg. Fucoidan-use-case</obo:IAO_0000232>
<rdfs:label>treatment portion of study execution</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000827 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000827">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<obo:IAO_0000111>pill</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A dose of medicine or placebo in the form of a small pellet.</obo:IAO_0000115>
<obo:IAO_0000117>Person:Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000119>http://www.golovchenko.org/cgi-bin/wnsearch?q=pill#2n</obo:IAO_0000119>
<obo:IAO_0000232>2009/09/28 Alan Ruttenberg. Fucoidan-use-case</obo:IAO_0000232>
<rdfs:label>pill</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000828 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000828">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000245"/>
<obo:IAO_0000111>research organization</obo:IAO_0000111>
<obo:IAO_0000112>The SALK institute is a research organization.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An organization formed with a goal to have its members conduct investigations</obo:IAO_0000115>
<obo:IAO_0000117>Person:Bjoern Peters</obo:IAO_0000117>
<rdfs:label>research organization</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000830 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000830">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_primary structure of sequence macromolecule</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A quality inhering in a molecule that is completely defined by the linear sequence of a set of residues which are connected by directional, linear bonds</obo:IAO_0000115>
<obo:IAO_0000117>Person:Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<rdfs:label>obsolete_primary structure of sequence macromolecule</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000831 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000831">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001241"/>
<obo:IAO_0000111>DNA residue methylation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a quality of a DNA residue that has a methyl group attached to it</obo:IAO_0000115>
<rdfs:label>DNA residue methylation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000832 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000832">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000968"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<obo:IAO_0000111>measurement device</obo:IAO_0000111>
<obo:IAO_0000112>A ruler, a microarray scanner, a Geiger counter.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A device in which a measure function inheres.</obo:IAO_0000115>
<obo:IAO_0000117>GROUP:OBI Philly workshop</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>measurement device</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000834 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000834">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001051"/>
<obo:IAO_0000111>high molecular weight DNA extract</obo:IAO_0000111>
<obo:IAO_0000112>Extraction of chromosomal DNA from mammalian cells by first isolating nucei</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The output of an extraction process in which DNA molecules above a molecular weight cutoff are purified in order to exclude DNA from organellas.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>high molecular weight DNA extract</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000835 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000835">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000245"/>
</owl:unionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000571"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000111>manufacturer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A person or organization that has a manufacturer role.</obo:IAO_0000115>
<rdfs:label>manufacturer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000836 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000836">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000522"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000370"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>test tube</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A test tube is a device consisting of a glass or plastic tubing, open at the top, usually with a rounded U-shaped bottom which has the function to contain material</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000118>collection tube</obo:IAO_0000118>
<obo:IAO_0000118>sample tube</obo:IAO_0000118>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Test_tube</obo:IAO_0000119>
<rdfs:label>test tube</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000837 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000837">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000952"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000319"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000827"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000827"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000952"/>
<obo:IAO_0000111>oral ingestion of pill</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An adding a material entity to target with the entity is a pill and the target is the mouth</obo:IAO_0000115>
<obo:IAO_0000117>Person:Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000232>2009/09/28 Alan Ruttenberg. Fucoidan-use-case</obo:IAO_0000232>
<rdfs:label>oral ingestion of pill</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000838 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000838">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000806"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<obo:IAO_0000111>material maintenance</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A planned process with the objective to maintain some or all of the characteristics of an input material over time.</obo:IAO_0000115>
<rdfs:label>material maintenance</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000839 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000839">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001936"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002744"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600038"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>labeled oligonucleotide</obo:IAO_0000111>
<obo:IAO_0000112></obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a labeled oligonucleotide is a short nucleic acid which underwent a labeling process resulting in a radioactive isotope such as P32 or P33 added to its backbone for instance by end labeling with polynucleotide kinase which added radiolabeled ATP to the 5' end of oligonucleotide</obo:IAO_0000115>
<obo:IAO_0000116>2010-01-31: Philippe Rocca-Serra
placeholder</obo:IAO_0000116>
<obo:IAO_0000117>Person: Philippe Rocca-Serra</obo:IAO_0000117>
<rdfs:label>labeled oligonucleotide</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000840 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000840">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000471"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000842"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>unblinding process</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A planned process that is the part of the study execution in which the subjects are told what study arm they are in and in which the investigators are told which subjects are in which trials.</obo:IAO_0000115>
<obo:IAO_0000117>Person:Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000232>2009/09/28 Alan Ruttenberg. Fucoidan-use-case</obo:IAO_0000232>
<rdfs:label>unblinding process</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000841 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000841">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000810"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>subject agrees they understand informed consent document</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A planned process in which a subject receives an informed consent document and agrees that they have understood it.</obo:IAO_0000115>
<obo:IAO_0000116>09/28/2009 Alan Ruttenberg. There's a need for a general process like this in IAO - document and person in, signed document (and associated obligations, rights, out</obo:IAO_0000116>
<obo:IAO_0000117>Person:Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000232>2009/09/28 Alan Ruttenberg. Fucoidan-use-case</obo:IAO_0000232>
<rdfs:label>subject agrees they understand informed consent document</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000842 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000842">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000810"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000097"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>informing subject of study arm</obo:IAO_0000111>
<obo:IAO_0000112>Informing participants whether they are receiving a placebo or a treatment with an investigational compound.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A planned process with the objective to make the subject aware of which study arm they are participating in.</obo:IAO_0000115>
<obo:IAO_0000116>09/28/2009 Alan Ruttenberg. This and the class informing-investigator-of-study-arm are defined in order to solve the question of how to represent single and double blind experiments. To represent the aspect of blinding pertaining to subjects (happens in single and double blinding) we say that that the study execution doesn't include any processes of this sort</obo:IAO_0000116>
<obo:IAO_0000117>Person:Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000232>2009/09/28 Alan Ruttenberg. Fucoidan-use-case</obo:IAO_0000232>
<rdfs:label>informing subject of study arm</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000843 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000843">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
<owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/OBI_0000829"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>Sysmex CA-6000 Coagulation Analyzer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The Sysmex CA-6000 automated coagulation analyzer is a random access instrument that is capable of performing 20 clot-based and chromogenic assays</obo:IAO_0000115>
<obo:IAO_0000117>Person:Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000119>web:http://www.clinchem.org/cgi/content/full/43/9/1783@2009/08/06</obo:IAO_0000119>
<obo:IAO_0000232>2009/09/28 Alan Ruttenberg. Fucoidan-use-case</obo:IAO_0000232>
<rdfs:label>Sysmex CA-6000 Coagulation Analyzer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000844 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000844">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete hospital</obo:IAO_0000111>
<obo:IAO_0000112>human ethics approval was obtained from the Southern Tasmania Health & Medical Human Research Ethics Committee and the Royal Hobart Hospital Research Ethics Committee [pmid:19696660]</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A medical organization at which sick or injured people are given clinical care</obo:IAO_0000115>
<obo:IAO_0000117>Person:Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000117>Person:Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000119>modified from the wording of the wordnet definition; http://www.golovchenko.org/cgi-bin/wnsearch?q=hospital#2n</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1295</obo:IAO_0000233>
<obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/OMRSE_00000056"/>
<rdfs:label>obsolete hospital</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000845 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000845">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000058"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33697"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/SO_0000001"/>
<obo:IAO_0000111>primary structure of RNA molecule</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">The primary structure of an RNA molecule that is completely defined by the set of its nucleic residue parts and the linear order induced by the peptide bonds that hold them together</obo:IAO_0000115>
<obo:IAO_0000117>Person:Bjoern Peters</obo:IAO_0000117>
<rdfs:label>primary structure of RNA molecule</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000847 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000847">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<obo:IAO_0000111>test substance role</obo:IAO_0000111>
<obo:IAO_0000112>fucoidan bears a test substance role in a study to test safety taking a certain dosage of it orally</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A role born by a material entity and realized in a process where the substance is used as specified as the independent variable for an investigation</obo:IAO_0000115>
<obo:IAO_0000117>Person:Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000119>Group:OBI</obo:IAO_0000119>
<rdfs:label>test substance role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000848 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000848">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0666666"/>
<obo:IAO_0000111>polyA RNA extraction</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A RNA extraction process typically involving the use of poly dT oligomers in which the desired output material is polyA RNA.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Person: Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>UPenn Group</obo:IAO_0000119>
<rdfs:label>polyA RNA extraction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000849 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000849">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0666666"/>
<obo:IAO_0000111>organellar RNA extraction</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A RNA extraction process in which the desired output material is RNA in the organelle(s).</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Person: Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>UPenn Group</obo:IAO_0000119>
<rdfs:label>organellar RNA extraction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000851 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000851">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_diethyl pyrocarbonate</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<rdfs:label>obsolete_diethyl pyrocarbonate</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000852 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000852">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
<obo:IAO_0000111>record of missing knowledge</obo:IAO_0000111>
<obo:IAO_0000112>A statement in a journal article indicating that the age of a patient at the onset of disease is not known. A statement indicating that the weight of a mouse was not measured.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An information content entity created to indicate that information about something is not available to the person recording it.</obo:IAO_0000115>
<obo:IAO_0000116>This class should probably end up in IAO. It could be further breaken down to indicate different kinds of lack of knowledge, e.g. inability to determine something vs. no attempt made to determine something vs. no informatino available if it was even attempted to determine something. The design pattern should be generalizable. 'unknown sex' is the first example, and needed immediately.</obo:IAO_0000116>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119></obo:IAO_0000119>
<rdfs:label>record of missing knowledge</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000854 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000854">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001978"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16670"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16670"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>western blot assay</obo:IAO_0000111>
<obo:IAO_0000112>Running a cell lysate on an acrylamide gel in a western blot aparatus to separate the constituent proteins, followed by transfer of the proteins from the gel to a nitrocellulose membrane. Staining this membrane with specific antibodies to detect the presence of specific proteins of interest.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that detects specific peptides in an input material by separating it using gel electrophoresis, transfering the separated molecules to a membrane, and staining them with_ antibodies specific to the analyte molecules.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:IAO_0000119>Philippe Rocca-Serra</obo:IAO_0000119>
<rdfs:label>western blot assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000855 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000855">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0666666"/>
<obo:IAO_0000111>total RNA extraction</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A RNA extraction process in which total cellular and organelle RNA are extracted.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Person: Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>UPenn Group</obo:IAO_0000119>
<rdfs:comment></rdfs:comment>
<rdfs:label>total RNA extraction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000856 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000856">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete intracellular material detection by flow cytometry assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An assay in which the presence of a material inside a cell is measured by permeabilizing the cell membrane to allow entry of specific antibodies, and counting the stained cells using a flow cytometer.</obo:IAO_0000115>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
<obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/OBI_0000916"/>
<obo:OBI_9991118>intracellular staining</obo:OBI_9991118>
<rdfs:label>obsolete intracellular material detection by flow cytometry assay</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000857 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000857">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33696"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>complementary nucleotide probe role</obo:IAO_0000111>
<obo:IAO_0000112>A primer in a PCR reaction. A probe on an Affymetrix chip.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A role played by a nucleic acid molecule that is used in a planned process for its ability to bind a nucleic acid molecules with complementary nucleotide sequence</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Bjoern Peters</obo:IAO_0000117>
<rdfs:label>complementary nucleotide probe role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000858 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000858">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000852"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000047"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>record of unknown sex</obo:IAO_0000111>
<obo:IAO_0000112>A database record indicating that the tissue sample in a microarray experiment came from an organism for which the biological sex is not known to the person who created the record.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a record indicating that the biological sex of an organism is not known.</obo:IAO_0000115>
<obo:IAO_0000116>I think the statement is still about the instance of the biological sex quality of an organism. It is also about information available to the person making the statement.</obo:IAO_0000116>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<rdfs:label>record of unknown sex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000859 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000859">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0666666"/>
<obo:IAO_0000111>cytoplasmic RNA extraction</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A RNA extraction process in which the desired output material is RNA in the cytoplasm.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Person: Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>UPenn Group</obo:IAO_0000119>
<rdfs:label>cytoplasmic RNA extraction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000860 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000860">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33697"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33697"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>northern blot assay</obo:IAO_0000111>
<obo:IAO_0000112>The level of actin mRNA levels in normal and diseased tiisue was measured using a northern blot assay.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An assay that determines the presence of gene transcripts by hybridizing labeled RNA or DNA probes against messenger RNAs isolated from tissue or cell cultures, resolved on denaturing gel, transfered by a blotting procedure to a solid support. Detection of hybridization signals is carried out by immunofluorescence or radioactivity measurements using photographic films or digital imaging devices such as Phosphor Imager.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000117>Richard Scheuermann</obo:IAO_0000117>
<obo:IAO_0000118>northern blot</obo:IAO_0000118>
<rdfs:label>northern blot assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000861 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000861">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200000"/>
<obo:IAO_0000111>Likelihood-ratio test</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Likelihood-ratio is a data transformation which tests whether there is evidence of the need to move from a simple model to a more complicated one (where the simple model is nested within the complicated one); tests of the goodness-of-fit between two models.</obo:IAO_0000115>
<obo:IAO_0000117>Tina Boussard</obo:IAO_0000117>
<rdfs:label>Likelihood-ratio test</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000862 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000862">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000880"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000888"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>nuclear RNA extract</obo:IAO_0000111>
<obo:IAO_0000112>Isolation and purification of nuclear RNA from animal cells using Norgen Bioteck corp. cytoplasmic and nuclear RNA purification kit (http://www.norgenbiotek.com/display-product.php?ID=30)</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A RNA extract that is the output of an extraction process in which RNA molecules found in the nucleus, including mRNA precursors (pre-mRNA), are extracted.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>UPenn Group</obo:IAO_0000119>
<rdfs:label>nuclear RNA extract</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000865 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000865">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000872"/>
<rdfs:subClassOf>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400076"/>
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</owl:Class>
</owl:someValuesFrom>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400076"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>96-well neutralization assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A serum neutralization of viral infectivity assay which is performed in a 96-well plate.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000118>microneutralization assay</obo:IAO_0000118>
<rdfs:label>96-well neutralization assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000867 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000867">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001867"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001906"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>establishing cancer cell line</obo:IAO_0000111>
<obo:IAO_0000112>Establishment of HeLa immortal cell line</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">is a planned process in which the objective is to generate a cell line from a natural population of cancer cells which are already immortal</obo:IAO_0000115>
<obo:IAO_0000119></obo:IAO_0000119>
<rdfs:comment>Helen Parkinson</rdfs:comment>
<rdfs:label>establishing cancer cell line</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000868 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000868">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200166"/>
<obo:IAO_0000111>pattern matching objective</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A pattern matching objective aims to detect the presence of the constituents of a given pattern. In contrast to pattern recognition, the pattern is rigidly specified. Patterns are typicall sequences or trees.</obo:IAO_0000115>
<obo:IAO_0000117>Tina Boussard</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Pattern_matching</obo:IAO_0000119>
<rdfs:label>pattern matching objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000869 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000869">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000880"/>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000848"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>polyA RNA extract</obo:IAO_0000111>
<obo:IAO_0000112>Preparation of polyA RNA by cellulose-bound oligo-dT (Aviv, H., Leder, P. 1972. Purification of biologically active globin messenger RNA by chromatography on oligothymidylic acid-cellulose. Proc. Nat. Acad. Sci. USA 69, 1408-1412.)</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A RNA extract that is the output of an extraction process in which RNA molecules with poly A tail at its 3' end are purified.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>UPenn Group</obo:IAO_0000119>
<rdfs:label>polyA RNA extract</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000870 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000870">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000885"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>single-nucleotide-resolution nucleic acid structure mapping assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that provides information about the secondary structure of nucleic acids using chemical or enzymatic probing to establish the extent of base-pairing or solvent accessiblity.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>RNAO</obo:IAO_0000119>
<rdfs:label>single-nucleotide-resolution nucleic acid structure mapping assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000871 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000871">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000906"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>viral hemagglutination assay</obo:IAO_0000111>
<obo:IAO_0000112>Determining the viral titer of a virus infected human by measuring the presence of hemagglutination when dilutions of serum samples are added to a known quantity of red blood cells.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that quantifies viruses by their hemagglutination activity.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
<obo:IAO_0000118>HA</obo:IAO_0000118>
<obo:IAO_0000118>HI</obo:IAO_0000118>
<obo:IAO_0000118>viral haemagglutinin assay</obo:IAO_0000118>
<obo:IAO_0000119>url:http://en.wikipedia.org/wiki/Hemagglutination_assay</obo:IAO_0000119>
<rdfs:label>viral hemagglutination assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000872 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000872">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf>
<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100017"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
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<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000086"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10239"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10239"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0097282"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>serum neutralization of viral infectivity assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures virus-neutralizing abilities of different sera. Different dilutions of serum are mixed with virus and used to infect cells. At the lower dilutions, antibodies will block infection, but at higher dilutions, there will be too few antibodies to have an effect.The neutralization titer is expressed as the reciprocal of the highest dilution at which virus infection is blocked.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000118>influenza neutralization assay</obo:IAO_0000118>
<obo:IAO_0000119>url:http://www.virology.ws/2009/05/28/influenza-microneutralization-assay/</obo:IAO_0000119>
<rdfs:label>serum neutralization of viral infectivity assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000873 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000873">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001506"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
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<owl:Class>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000659"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100026"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000086"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0001421"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001506"/>
<obo:IAO_0000111>pre-mortem specimen</obo:IAO_0000111>
<obo:IAO_0000112>material obtained through a liver biopsy from a human patient</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a specimen that was taken from a live organism</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>MO_705 premortem</obo:IAO_0000119>
<rdfs:label>pre-mortem specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000874 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000874">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_33696"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000857"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000857"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33696"/>
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</owl:intersectionOf>
</owl:Class>
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</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33696"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<obo:IAO_0000111>detection of specific nucleic acid polymers with complementary probes</obo:IAO_0000111>
<obo:IAO_0000112>Primer based PCR assay, Norther blot, Southern Blot, and RNAse protection assays.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay in which a specified input material (the evaluant) is examined for the presence or quantity of specified nucleic acid polymers, which are identified based on the use of complementary nucleic acid probes.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>detection of specific nucleic acid polymers with complementary probes</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000875 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000875">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<rdfs:subClassOf>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10239"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10239"/>
</owl:Restriction>
</owl:intersectionOf>
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</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000906"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>viral hemagglutination inhibition assay</obo:IAO_0000111>
<obo:IAO_0000112>Examining the ability of a monoclonal antibody to inhibit hemagglutination by Influenza A virus by comparing the levels of hemagglutination with and without the presence of the antibody.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures the ability of an evaluant to inhibit hemagglutination by a virus. Hemagglutinin is a viral protein which binds to sialic acid receptors on cells or to erythrocytes, causing the cells to clump. Loss of clumping indicates that the evaluant blocks binding of hemagglutinin to sialic acid receptors.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
<obo:IAO_0000118>HAI</obo:IAO_0000118>
<obo:IAO_0000118>HIA</obo:IAO_0000118>
<obo:IAO_0000118>biological activity</obo:IAO_0000118>
<obo:IAO_0000118>hemagglutination inhibition</obo:IAO_0000118>
<obo:IAO_0000118>viral haemagglutinin inhibition assay</obo:IAO_0000118>
<obo:IAO_0000119>OBI branch derived</obo:IAO_0000119>
<rdfs:label>viral hemagglutination inhibition assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000876 -->
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</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000880"/>
<obo:IAO_0000111>cytoplasmic RNA extract</obo:IAO_0000111>
<obo:IAO_0000112>Cytoplasmic RNA extraction from mammalian tissues to create cDNA library (Carninci P, Nakamura M, Sato K, Hayashizaki Y, Brownstein MJ. Cytoplasmic RNA extraction from fresh and frozen mammalian tissues. Biotechniques. 2002;33:306–309.)</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A RNA extract that is the output of a RNA extraction process in which RNA molecules found in the cytoplasm are extracted.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>UPenn Group</obo:IAO_0000119>
<rdfs:label>cytoplasmic RNA extract</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000877 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000877">
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CLO_0009828"/>
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<obo:IAO_0000111>cell line immortalization</obo:IAO_0000111>
<obo:IAO_0000112>Production of a cell line for the purposes of experimentation e.g. EBV transformation of PBMs</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">an establishing cell line process whereby a mortal cell line is intentionally genetically modified to be capable of indefinite propagation and re-established as a new immortal cell line</obo:IAO_0000115>
<obo:IAO_0000116>4-20-13 MHB: This class was repositioned as a child of 'establishing cell line', based on the existing definition ("the planned process of experimentally creating a cell line which is capable of dividing indefinitely in vitro"), and examples and other annotations indicating the intent to describe a process through which a new immortal cell line is established from an existing mortal cell line using genetic modification techniques. The definition above was modified to clarify this perspective.</obo:IAO_0000116>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000118>'establishing immortal cell line through directed genetic modification'</obo:IAO_0000118>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:comment>A immortalizing genetic transformation of an existing population of cell line cells is required as part of this process, as are additional steps for selecting and propagating the cells output form this process into a cell line.</rdfs:comment>
<rdfs:label>cell line immortalization</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000879 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000879">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600038"/>
<obo:IAO_0000111>random primed DNA labeling</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 8713846. Random primed 32P-labeling of DNA. Smith DR.
Methods Mol Biol. 1996;58:27-9.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a labeling in which random primers are used to uniformly label input DNA</obo:IAO_0000115>
<obo:IAO_0000116>need to add Klenow subunit of DNA polymerase I under material entity</obo:IAO_0000116>
<obo:IAO_0000117>Person: Bjoern Peters
Person: Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Person: Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>PMID: 6312838. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Feinberg AP, Vogelstein B. Anal Biochem. 1983 Jul 1;132(1):6-13.</obo:IAO_0000119>
<rdfs:label>random primed DNA labeling</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000880 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000880">
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<obo:IAO_0000111>RNA extract</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">an extract which is the output of an extraction process in which RNA molecules are isolated from a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>Group: UPenn Group</obo:IAO_0000119>
<rdfs:label>RNA extract</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000882 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000882">
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
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<obo:IAO_0000111>cell-cell killing assay</obo:IAO_0000111>
<obo:IAO_0000112>Autologous EBV-transformed B-LCL were used as target cells for the influenza virus-specific CTL assays. Equal volumes of target and effector cells were added to tissue culture plates, and 1:2 serial dilutions of effectors were made. After a 4-h incubation of the effector cells with the target cells, supernatants were collected and counted with the LKB 1272 Clinigamma counter. Percent specific killing was determined with the following equation: (experimental 51Cr release - spontaneous 51Cr release)/(maximum 51Cr release - spontaneous 51Cr release) x 100.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that monitors a cell population to track how many are killed by other cells.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>cell-cell killing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000883 -->
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
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</owl:someValuesFrom>
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</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000882"/>
<obo:IAO_0000111>in vivo cell killing assay</obo:IAO_0000111>
<obo:IAO_0000112>Labeling two populations of cells with different levels of CFSE, pusling one population with an influenza peptide, injecting the cells into a mouse, and recoving cells 24 hours later. By comparing the recovery rate of cells with different CFSE labeling, it is possible to determine if there was specific killing of peptide pulsed target cells.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cell killing assay that measures if and how many target cells are killed within an organism.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>in vivo cell killing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000885 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000885">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001241"/>
<obo:IAO_0000111>secondary structure of sequence macromolecule</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000002"/>
<obo:IAO_0000115 xml:lang="en">A quality inhering in a molecule that refers to general three-dimensional form of local segments of biopolymers such as proteins and nucleic acids (DNA/RNA). It does not, however, describe specific atomic positions in three-dimensional space, which are considered to be tertiary structure.
Secondary structure was introduced by Kaj Ulrik Linderstrøm-Lang in the 1952 Lane medical lectures at Stanford.</obo:IAO_0000115>
<obo:IAO_0000116>2010-01-31: Philippe Rocca-Serra: This is a placeholder to allow work on 'nucleic acid mapping assay' in collaboration with RNAOntology group. Need to liaise with SO</obo:IAO_0000116>
<obo:IAO_0000117>Person: Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>Wikipedia</obo:IAO_0000119>
<rdfs:label>secondary structure of sequence macromolecule</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000888 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000888">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0666666"/>
<obo:IAO_0000111>nuclear RNA extraction</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A RNA extraction process in which the desired output material is RNA in the nucleus.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Person: Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>UPenn Group</obo:IAO_0000119>
<rdfs:label>nuclear RNA extraction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000889 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000889">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000573"/>
<rdfs:subClassOf>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000789"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">survival curve</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A survival curve is a report graph which is a graphical representation of data where the percentage of survival is plotted as a function of time.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON:Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">PERSON:James Malone</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">PERSON:Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">WEB: http://www.graphpad.com/www/book/survive.htm</obo:IAO_0000119>
<rdfs:label xml:lang="en">survival curve</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000891 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000891">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0008283"/>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001977"/>
<obo:IAO_0000111>cell proliferation assay</obo:IAO_0000111>
<obo:IAO_0000112>Measuring the amount of tritiated thymidine incorporated by dividing cells as a proxy for cell proliferation.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay which measures the degreee to which input cells are replicating.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>cell proliferation assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000892 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000892">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<rdfs:subClassOf>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001051"/>
</owl:Restriction>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0302903"/>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000874"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003368"/>
</owl:intersectionOf>
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</owl:Restriction>
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<rdfs:subClassOf>
<owl:Restriction>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
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<owl:someValuesFrom>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000029"/>
</owl:Restriction>
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<obo:IAO_0000111>Southern blot assay</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 9452032. Germline mutations detected in the von Hippel-Lindau disease tumor suppressor gene by Southern blot and direct genomic DNA sequencing.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that detects the presence of a specific sequence in a DNA sample, which has been digested by restriction enzymes, resolved by gel electrophoresis, and blotted to a solid support, followed by hybridization of a probe raised against a specific sequence and detected with fluorescence or radioactivity.</obo:IAO_0000115>
<obo:IAO_0000117>Marcus Chibucos</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>Southern blot</obo:IAO_0000118>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>Southern blot assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000893 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000893">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002692"/>
<rdfs:subClassOf>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000415"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>real time polymerase chain reaction assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay, based on the PCR, that amplifies and simultaneously quantifies a specific DNA molecule based on the use of complementary probes/primers. It enables both detection and quantification (as absolute number of copies or relative amount when normalized to DNA input or additional normalizing genes) of one or more specific sequences in a DNA sample.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000118>Q-PCR</obo:IAO_0000118>
<obo:IAO_0000118>kinetic polymerase chain reaction</obo:IAO_0000118>
<obo:IAO_0000118>qPCR</obo:IAO_0000118>
<obo:IAO_0000118>quantitative real time polymerase chain reaction</obo:IAO_0000118>
<obo:IAO_0000119>url:http://en.wikipedia.org/wiki/Real-time_polymerase_chain_reaction</obo:IAO_0000119>
<rdfs:label>real time polymerase chain reaction assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000894 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000894">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000423"/>
<rdfs:subClassOf>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0302884"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>protein extract</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 20032479. A bovine whey protein extract stimulates human neutrophils to generate bioactive IL-1Ra through a NF-kappaB- and MAPK-dependent mechanism. Rusu D, Drouin R, Pouliot Y, Gauthier S, Poubelle PE.
J Nutr. 2010 Feb;140(2):382-91. Epub 2009 Dec 23.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a protein extract is the output of an extraction process from tissues or cell cultures resulting in a solution of cellular and/or organellar proteins in buffer solution used to prevent degradation,</obo:IAO_0000115>
<obo:IAO_0000117>Person: Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>OBI & wikipedia</obo:IAO_0000119>
<rdfs:label>protein extract</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0000895 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000880"/>
<obo:IAO_0000111>total RNA extract</obo:IAO_0000111>
<obo:IAO_0000112>Extraction of total RNA from cells with Qiagen mini RNeasy kit</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A RNA extract that is the output of an extraction process in which total celluar and organelle RNA molecules are isolated from a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>UPenn Group</obo:IAO_0000119>
<rdfs:label>total RNA extract</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000896 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000896">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000885"/>
<obo:IAO_0000111>secondary structure of RNA molecule</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 15630685: Single molecule studies of RNA secondary structure: AFM of TYMV viral RNA.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en"></obo:IAO_0000115>
<obo:IAO_0000116>2010-01-31: Philippe Rocca-Serra: This is a placeholder to allow work on 'nucleic acid mapping assay' in collaboration with RNAOntology group. Need to liaise with SO</obo:IAO_0000116>
<obo:IAO_0000117>Person: Philippe Rocca-Serra</obo:IAO_0000117>
<rdfs:label>secondary structure of RNA molecule</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000897 -->
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_33697"/>
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</owl:Restriction>
</owl:someValuesFrom>
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<obo:IAO_0000111>DEPC structure mapping assay</obo:IAO_0000111>
<obo:IAO_0000112>PMID:2446263. Probing the structure of RNAs in solution. Nucleic Acids Res. 1987 Nov 25;15(22):9109-28.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A single-nucleotide-resolution nucleic acid structure mapping assay which determines nucleic acid secondary structure at a nucleotide resolution scale using DEPC as reagent and chemical probe</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>RNA ontology</obo:IAO_0000119>
<rdfs:label>DEPC structure mapping assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000899 -->
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<owl:equivalentClass>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000849"/>
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</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000880"/>
<obo:IAO_0000111>organellar RNA extract</obo:IAO_0000111>
<obo:IAO_0000112>Extraction of organellar RNA from plant cells using organellar RNA binding protein.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A RNA extract that is the output of an extraction process in which RNA molecules found in an organelle, e.g., mitochondrion, ER, or chloroplast, excluding the nucleus, are extracted.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>UPenn Group</obo:IAO_0000119>
<rdfs:label>organellar RNA extract</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000902 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000902">
<owl:equivalentClass>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100026"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000086"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0001422"/>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001506"/>
<obo:IAO_0000111>post mortem specimen</obo:IAO_0000111>
<obo:IAO_0000112>the spleen taken from a dead mouse</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a specimen that was taken from a dead organism</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>MO_416 postmortem</obo:IAO_0000119>
<rdfs:label>post mortem specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000903 -->
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<owl:equivalentClass>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100060"/>
</owl:Restriction>
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</owl:Class>
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<owl:Restriction>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
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</owl:intersectionOf>
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</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000882"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003587"/>
<obo:IAO_0000111>in vitro cell killing assay</obo:IAO_0000111>
<obo:IAO_0000112>Autologous EBV-transformed B-LCL were used as target cells for the influenza virus-specific CTL assays. Equal volumes of target and effector cells were added to tissue culture plates, and 1:2 serial dilutions of effectors were made. After a 4-h incubation of the effector cells with the target cells, supernatants were collected and counted with the LKB 1272 Clinigamma counter. Percent specific killing was determined with the following equation: (experimental 51Cr release - spontaneous 51Cr release)/(maximum 51Cr release - spontaneous 51Cr release) x 100.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cell killing assay that measures if and how many target cells are actively killed by other cells in a cell culture.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>in vitro cell killing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000904 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000904">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CLO_0000031"/>
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</owl:intersectionOf>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CLO_0000031"/>
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<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600024"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>reporter cell line analyte detection bioassay</obo:IAO_0000111>
<obo:IAO_0000112>CTLL-2 cells were grown in the presence of hybridoma supernatants and their growth was monitored by a 3H-thymidine incorporation cell proliferation assay in order to detect IL-2 in the hybridoma supernatant.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay in which a cell line whose growth is known to be affected by the presence of a specific type of material (the anlyte) is cultured in the presence of an input material (the evaluant) in order to detect presence of the analyte in the evaluant.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>reporter cell line analyte detection bioassay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000905 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000905">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
<obo:IAO_0000111>sequence feature annotation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Information about a sequence region</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>Bjoern Peters</obo:IAO_0000119>
<rdfs:comment>place holder for sequence ontology term</rdfs:comment>
<rdfs:label>sequence feature annotation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000906 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000906">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000232"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>induced hemagglutination</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The clumping or clustering of red blood cells caused by certain viruses, antibodies, or other substances</obo:IAO_0000115>
<obo:IAO_0000116>MC, 20100217: This term was originally submitted to GO, see discussion at http://sourceforge.net/tracker/index.php?func=detail&aid=2947975&group_id=36855&atid=440764. After discussion it was agreed that this isn't a natural in vivo process and therefore out of scope for GO.
Dev call Nov 22, 2010: To reflect this, the term's label has been updated to 'induced hemagglutination'.</obo:IAO_0000116>
<obo:IAO_0000117>person: Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>person: Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000118>hemeagglutination</obo:IAO_0000118>
<obo:IAO_0000119>WEB: http://medical-dictionary.thefreedictionary.com/hemagglutination</obo:IAO_0000119>
<rdfs:label>induced hemagglutination</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000907 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000907">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>supplying</obo:IAO_0000111>
<obo:IAO_0000112>Jackson Labs supplies mouse strains.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A planned process with the objective to provide material entities to be used in an investigation.</obo:IAO_0000115>
<obo:IAO_0000117>Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000119>Jennifer Fostel</obo:IAO_0000119>
<obo:IAO_0000232>5/31/2012: A supplying process implies that there is an acquisition process. These may need to be tied together, so that modeling either way is reciprocal.</obo:IAO_0000232>
<rdfs:label>supplying</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000908 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000908">
<owl:equivalentClass>
<owl:Class>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001143"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0600038"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001051"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16991"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001143"/>
<obo:IAO_0000111>labeled DNA extract</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a labeled specimen that is the output of a labeling process and has grain labeled DNA to be able to detect DNA in future experiments.</obo:IAO_0000115>
<obo:IAO_0000116>Need to find out if we consider labeled nucleotides still nucleotides. It is after consulting with ChEBI group. Added duirng Mar 1, 2010 dev call</obo:IAO_0000116>
<obo:IAO_0000117>Group: OBI group</obo:IAO_0000117>
<obo:IAO_0000119>Group: OBI group</obo:IAO_0000119>
<rdfs:label>labeled DNA extract</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000909 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000909">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000162"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>cell specimen</obo:IAO_0000111>
<obo:IAO_0000112>type of sample used in the PCIRN influenza network</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen obtained by inserting a swab deeply into the vent of the cloaca of an organism and vigorously swabbing the wall. The swab should be deeply stained with fecal material and is then placed in transport medium.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000119>WEB: http://www.wpro.who.int/NR/rdonlyres/EFD2B9A7-2265-4AD0-BC98-97937B4FA83C/0/manualonanimalaidiagnosisandsurveillance.pdf</obo:IAO_0000119>
<rdfs:label>cloacal specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000910 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000910">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<rdfs:subClassOf>
<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002743"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
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<owl:Class>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000053"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0001741"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000053"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0001741"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>radio immuno assay</obo:IAO_0000111>
<obo:IAO_0000112>To evaluate the specificity of antibody binding to 35S-labeled IA-2(256-760) in comparison with 35S-labeled IA-2IC construct, the mutual inhibition activity of different concentrations of unlabeled IA-2IC and/or IA-2(256-760) fragments were tested. Unlabeled recombinant IA-2(256-760) and/or IA-2IC (0.5-, 1-, 2-, and 4-fold the amount of 35S-labeled protein) were added to each tube and incubated overnight at 4C with patient sera. The following day, after incubation with radiolabeled 35 IA-2(256-760) or 35S IA-2IC proteins, samples were processed with the usual radioimmunoprecipitation assay.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay in which a radioactive labeled antigen or antibody is used to determine the interaction between an antigen and its receptor. This can be used to detect the presence of an antigen of interest in an input sample or determine the specificity of an input antibody.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>radio immuno assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000911 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000911">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002692"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600028"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000893"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003368"/>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0010467"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>real time reverse-transcription polymerase chain reaction assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that uses a reverse transcription step (an RNA strand is reverse transcribed into its DNA complement using the enzyme reverse transcriptase) before a PCR assay.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000118>RRT-PCR</obo:IAO_0000118>
<obo:IAO_0000118>RT-rt PCR</obo:IAO_0000118>
<obo:IAO_0000118>qRT-PCR</obo:IAO_0000118>
<rdfs:label>real time reverse-transcription polymerase chain reaction assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000912 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000912">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003117"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001138"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001138"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>X-ray crystallography 3D molecular structure determination assay</obo:IAO_0000111>
<obo:IAO_0000112>Crystallizing an antibody:antigen complex, and recording the diffraction pattern of a synchrotron beam, and assembling the 3d complex structure based on homologous complexes.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A 3D molecular structure determination assay in which the diffraction of pattern of X-ray beams in a crystal of purified material entities is used to resolve the 3-dimensional structure of the material entity of interest.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>X-ray crystallography 3D molecular structure determination assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000913 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000913">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0001046"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>promoter activity detection by reporter gene assay</obo:IAO_0000111>
<obo:IAO_0000112>A T cell hybridoma in which the beta-galactosidase gene (lacZ) was inserted under the control of the IL-2 promoter, is detected by adding the X-gal substrate which when cleaved by lacZ results in detectable blue color.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay in which the activity of a promoter in a cell is monitored by using a reporter gene that was inserted in a genomic location under control of the promoter and whose expression can be easily detected based on qualities or functions of the gene.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>promoter activity detection by reporter gene assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000914 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000914">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2000007"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001728"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002785"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>nasopharyngeal aspirate specimen</obo:IAO_0000111>
<obo:IAO_0000112>type of sample used in the PCIRN influenza network</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen which derives from nasopharyngeal mucosa after aspiration.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000119>WEB: http://www.wpro.who.int/NR/rdonlyres/EFD2B9A7-2265-4AD0-BC98-97937B4FA83C/0/manualonanimalaidiagnosisandsurveillance.pdf</obo:IAO_0000119>
<rdfs:label>nasopharyngeal aspirate specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000915 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000915">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0302893"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000086"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0001985"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000086"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0001985"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000806"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>freezing storage</obo:IAO_0000111>
<obo:IAO_0000112>a fozen pellet used for later assay</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A storage process in temperature that maintenance the frozen status of the stored entities.</obo:IAO_0000115>
<obo:IAO_0000116>2010/3/3 Alan Ruttenberg: There is a question of whether we should have a separate objective to "prepare for maintenance"
2014/2/3 OBI dev call: "prepare for maintenance" is a separate process. For example, 'freezing' and 'flash freezing' are defined and can be used to produce frozen material for storage.
Updated both textual and logical definition. Both input and output material of freezing storage have quality frozen.</obo:IAO_0000116>
<obo:IAO_0000117>Person: Alan Ruttenberg, Mathias Brochhausen</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">MO_481 frozen_storage</obo:IAO_0000119>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>freezing storage</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000916 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000916">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001977"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400044"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400044"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001501"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003368"/>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001977"/>
<obo:IAO_0000111>flow cytometry assay</obo:IAO_0000111>
<obo:IAO_0000112>Using a flow cytometer to quantitate the percent of CD3 positive cells in a population by labeling them with a FITC tagged anti-CD3 antibody.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay in which an input cell population is put in solution, is passed by a laser, and optical sensors are used to detect scattering of the laser light and/or fluorescence of specific markers to count and characterize the particles in solution.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000118>FACS</obo:IAO_0000118>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>flow cytometry assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000917 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000917">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_2000006"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002600"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000659"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001826"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002599"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2000006"/>
<obo:IAO_0000111>nasal swab specimen</obo:IAO_0000111>
<obo:IAO_0000112>type of sample used in the PCIRN influenza network</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen obtained using a cotton swab on a stick, passed up the nostril to obtain a sample of exudate and epithelial debris for microbiological or cellular examination.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000119>WEB: http://www.wpro.who.int/NR/rdonlyres/EFD2B9A7-2265-4AD0-BC98-97937B4FA83C/0/manualonanimalaidiagnosisandsurveillance.pdf</obo:IAO_0000119>
<rdfs:label>nasal swab specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000918 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000918">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000079"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17234"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33709"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>Dulbecco's modified Eagle medium</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A culture medium containing iron, phenol red, amino acids, salts, glucose and vitamins.</obo:IAO_0000115>
<obo:IAO_0000116>Logical definition should contain all components listed in textual definition at some point.</obo:IAO_0000116>
<obo:IAO_0000117>PERSON:Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000118>D-MEM</obo:IAO_0000118>
<obo:IAO_0000118>DMEM</obo:IAO_0000118>
<rdfs:label>Dulbecco's modified Eagle medium</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000919 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000919">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600006"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_7742"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>animal euthanization</obo:IAO_0000111>
<obo:IAO_0000112>Rats were euthanized with CO2</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A process in which is the end of life of animal is brought about in accordance with local regulations on treatment of animal subjects and using a method which causes minimal pain and distress to the animal subject</obo:IAO_0000115>
<obo:IAO_0000117>Helen Parkinson and Melissa Haendel</obo:IAO_0000117>
<obo:IAO_0000118>animal sacrifice</obo:IAO_0000118>
<obo:IAO_0000119>Melissa Haendel</obo:IAO_0000119>
<rdfs:comment>may later be refined with more specific list of organisms</rdfs:comment>
<rdfs:label>animal euthanization</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000920 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000920">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000086"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1000207"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1000207"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001501"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003368"/>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<obo:IAO_0000111>cytometric bead array assay</obo:IAO_0000111>
<obo:IAO_0000112>Using a Luminex machine to detect IFN-gamma and IL-10 in the supernatant of a cell culture.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay in which a series of beads coated with antibodies, antigens, or other small molecules are used to detect an analyte of interest.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000118>Luminex assay</obo:IAO_0000118>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>cytometric bead array assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000921 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000921">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001143"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0600038"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000880"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33697"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001143"/>
<obo:IAO_0000111>labeled RNA extract</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a labeled specimen that is the output of a labeling process and has grain labeled RNA to be able to detect RNA in future experiments.</obo:IAO_0000115>
<obo:IAO_0000116>Need to find out if we consider labeled nucleotides still nucleotides. It is after consulting with ChEBI group. Added duirng Mar 1, 2010 dev call</obo:IAO_0000116>
<obo:IAO_0000117>Group: OBI group</obo:IAO_0000117>
<obo:IAO_0000119>Group: OBI group</obo:IAO_0000119>
<rdfs:label>labeled RNA extract</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000922 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000922">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100051"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000915"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000112"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001472"/>
<obo:IAO_0000111>frozen specimen</obo:IAO_0000111>
<obo:IAO_0000112>Frozen blood plasma</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A specimen that has been frozen in order to store it.</obo:IAO_0000115>
<obo:IAO_0000117>Person:Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000119>MO_610 frozen_sample</obo:IAO_0000119>
<rdfs:label>frozen specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000923 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000923">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001146"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001136"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001136"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>surface plasmon resonance binding assay</obo:IAO_0000111>
<obo:IAO_0000112>Running a Biacore instrument to measure the affinity, on and off rates of binding of a plate bound antibody to a antigen passing by in flow.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A binding assay that uses the detection of electromagnetic waves in a surface to detect material entities adsorbed to the surface, which change the local optical index of refraction.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>surface plasmon resonance binding assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000924 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000924">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100051"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002744"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600038"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000953"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001936"/>
<obo:IAO_0000111>labeled specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A specimen that has been modified in order to be able to detect it in future experiments</obo:IAO_0000115>
<obo:IAO_0000116>added during call 3/1/2010</obo:IAO_0000116>
<obo:IAO_0000117>OBI group</obo:IAO_0000117>
<rdfs:label>labeled specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000925 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000925">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000053"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110093"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
<obo:IAO_0000111>infectious agent</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">is a material entity bearing the disposition to infect an organism</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">infectious agent</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000926 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000926">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_ambidexterious handedness</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_ambidexterious handedness</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000927 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000927">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0302893"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000806"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>lyophilization storage</obo:IAO_0000111>
<obo:IAO_0000112></obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a storage process with input material entity and output freeze dried material for long time storage</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119></obo:IAO_0000119>
<rdfs:comment>can link to freezing-dying equipment, such as freeze-dryer, rotary evaporator, if needed</rdfs:comment>
<rdfs:label>lyophilization storage</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000928 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000928">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
<obo:IAO_0000111>material combination function</obo:IAO_0000111>
<obo:IAO_0000112>A stirrer has a material combination function</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A material separation function is a function that decreases the resolution between two or more material entities.</obo:IAO_0000115>
<obo:IAO_0000117>Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>material combination function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000929 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000929">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_training service provider role</obo:IAO_0000111>
<obo:IAO_0000112>EBI provides training on databases and tools and has a training service provider role</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a service provider role which is realized by a servicer provider organization performing some training</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_training service provider role</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000930 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000930">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>calorimeter</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A measurement device that is used to calculate the heat flow of a chemical reaction or physical change.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000118>calorimetry instrument?</obo:IAO_0000118>
<obo:IAO_0000119>http://chemistry.about.com/od/chemistryglossary/a/calorimeterdef.htm</obo:IAO_0000119>
<rdfs:label>calorimeter</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000931 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000931">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100051"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100051"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000471"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000059"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000115"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>study intervention</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A planned process that is the part of the execution of an intervention design study which is varied between two or more subjects in the study.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>GROUP: OBI</obo:IAO_0000119>
<rdfs:label>study intervention</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000932 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000932">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000968"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000372"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<obo:IAO_0000111>material separation device</obo:IAO_0000111>
<obo:IAO_0000112>flow cytometer</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A device with a separation function realized in a planed process</obo:IAO_0000115>
<rdfs:label>material separation device</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000933 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000933">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000398"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000397"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>positron emission tomography scanner</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that produces a three-dimensional image or picture of functional processes in the body. It detects pairs of gamma rays emitted indirectly by a positron-emitting radionuclide (tracer), which is introduced into the body on a biologically active molecule.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000118>PET scanner?</obo:IAO_0000118>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Positron_emission_tomography</obo:IAO_0000119>
<rdfs:label>positron emission tomography scanner</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000934 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000934">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0600007"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000422"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000444"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001134"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000426"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600007"/>
<obo:IAO_0000111>intramuscular injection</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">is the injection of a material entity (bearing the administered substance role) into the muscle (bearing the target role) of an organism using a syringe</obo:IAO_0000115>
<rdfs:label>intramuscular injection</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000935 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000935">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000379"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>micromanipulator</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that is used to physically interact with a sample under a microscope, where a level of precision of movement is necessary that cannot be achieved by the unaided human hand.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Micromanipulator</obo:IAO_0000119>
<rdfs:label>micromanipulator</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000936 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000936">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_material access provider role</obo:IAO_0000111>
<obo:IAO_0000112>A person or organization who provides access to a DNA sequencer.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a service provider role which is realized by a servicer provider organization performing access to some material</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_material access provider role</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000937 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000937">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_left handedness</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<rdfs:label>obsolete_left handedness</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000938 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000938">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0001938"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001930"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>categorical measurement datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A measurement datum that is reported on a categorical scale.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000118>nominal mesurement datum</obo:IAO_0000118>
<obo:IAO_0000119>Bjoern Peters</obo:IAO_0000119>
<rdfs:label>categorical measurement datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000939 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000939">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000962"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<obo:IAO_0000111>training process</obo:IAO_0000111>
<obo:IAO_0000112>e.g. a training course run by a vendor on their instrument, a training service on a assay by a core facility</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a process that achieves a training objective</obo:IAO_0000115>
<rdfs:label>training process</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000940 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000940">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400169"/>
<obo:IAO_0000111>optical microscope</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A microscope that produces an image of an object by targeting it with an electro-magnetic beam in the visible frequency range</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Bjoern Peters</obo:IAO_0000117>
<rdfs:label>optical microscope</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000941 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000941">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000245"/>
</owl:unionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>service consumer role</obo:IAO_0000111>
<obo:IAO_0000112>A biologist who uses a sequencing services fulfills the role of a service consumer</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a role which inheres in a person who uses a service</obo:IAO_0000115>
<obo:IAO_0000117>Person:Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>service consumer role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000942 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000942">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0600007"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000422"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000444"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000426"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600007"/>
<obo:IAO_0000111>intradermal injection</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">is the injection of a material entity (bearing the administered substance role) into the dermis (bearing the target role) of an organism using a syringe</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Melanie Courtot</obo:IAO_0000117>
<rdfs:label>intradermal injection</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000943 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000943">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100051"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000086"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>chemical cleavage</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 20171258. Comparative reactivity of mismatched and unpaired bases in relation to their type and surroundings. Chemical cleavage of DNA mismatches in mutation detection analysis.Yakubovskaya MG, Belyakova AA, Gasanova VK, Belitsky GA, Dolinnaya NG.
Biochimie. 2010 Feb 18.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">chemical cleavage is a protocol application relying on a chemical compound to cause the fragmentation of an input material that is susceptible to that chemical agent</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>RNA ontology group</obo:IAO_0000119>
<rdfs:label>chemical cleavage</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000944 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000944">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0002201"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>handedness assay</obo:IAO_0000111>
<obo:IAO_0000112>The Edinburgh handedness assay is a specific method of determing handedness</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures the unequal distribution of fine motor skill between the left and right hands typically in human subjects by means of some questionnaire and scoring procedure.</obo:IAO_0000115>
<obo:IAO_0000117>Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000118>handedness test</obo:IAO_0000118>
<obo:IAO_0000119>url:http://en.wikipedia.org/wiki/Handedness</obo:IAO_0000119>
<rdfs:label>handedness assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000945 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000945">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001034"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000401"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>vibration isolation table</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that supports another device such as a precision instrument by isolating it from vibration that is transmitted from the floor.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>United States Patent 6877711</obo:IAO_0000119>
<rdfs:label>vibration isolation table</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000946 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000946">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
<obo:IAO_0000111>sterilization function</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a function to remove viable organisms from an input material</obo:IAO_0000115>
<rdfs:label>sterilization function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000947 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000947">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000245"/>
</owl:unionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>service provider role</obo:IAO_0000111>
<obo:IAO_0000112>Jackson Lab provides experimental animals, EBI provides training on databases, a core facility provides access to a DNA sequencer.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">is a role which inheres in a person or organization and is realized in in a planned process which provides access to training, materials or execution of protocols for an organization or person</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Helen Parkinson</obo:IAO_0000117>
<rdfs:label>service provider role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000948 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000948">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>oscilloscope</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that measures and displayes signal voltages, usually as a two-dimensional graph of one or more electrical potential differences (vertical axis) plotted as a function of time or of some other voltage (horizontal axis).</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Oscilloscope</obo:IAO_0000119>
<rdfs:label>oscilloscope</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000949 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000949">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<obo:IAO_0000111>accessed material role</obo:IAO_0000111>
<obo:IAO_0000112>the role of the DNA sequencer to which someone gets access to a period of time, e.g. by payment, or other mechanism</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">is realized in a planned process where the bearer participates</obo:IAO_0000115>
<obo:IAO_0000116>AR: rent a DNA sequencer for a period of time. two realizations, payment for the service and also when the person who pays for the service uses it</obo:IAO_0000116>
<rdfs:label>accessed material role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000950 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000950">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100051"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000977"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000112"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001472"/>
<obo:IAO_0000111>paraffin specimen</obo:IAO_0000111>
<obo:IAO_0000112>liver tissue embedded in paraffin</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a specimen that is output of a paraffin storage process in which specimen is embedded in paraffin</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_990 paraffin_sample</obo:IAO_0000119>
<rdfs:label>paraffin specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000951 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000951">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000115"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000750"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000931"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000995"/>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>compound treatment design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">an intervention design in which the treatment is the administration of a compound</obo:IAO_0000115>
<obo:IAO_0000116>This is meant to include all kinds of material administrations, including vaccinations, chemical compounds etc.</obo:IAO_0000116>
<obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>MO_555 compound_treatment_design</obo:IAO_0000119>
<rdfs:label>compound treatment design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000952 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000952">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0600007"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000444"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000165"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600007"/>
<obo:IAO_0000111>oral administration</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An administering substance in vivo into the mouth of an organism</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Melanie Courtot</obo:IAO_0000117>
<rdfs:label>oral administration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000953 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000953">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100051"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000047"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100051"/>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0100051"/>
<obo:IAO_0000111>processed specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that has been intentionally physically modified.</obo:IAO_0000115>
<obo:IAO_0000116>A tissue sample that has been sliced and stained for a histology study.</obo:IAO_0000116>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>Bjoern Peters</obo:IAO_0000119>
<rdfs:label>processed specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000954 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000954">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0600007"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000422"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000444"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002072"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000426"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600007"/>
<obo:IAO_0000111>subcutaneous injection</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">is the injection of a material entity (bearing the administered substance role) into the hypodermis (bearing the target role) of an organism using a syringe</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Melanie Courtot</obo:IAO_0000117>
<rdfs:label>subcutaneous injection</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000955 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000955">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000379"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>electrode puller</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device used in the first step in making electrodes, that applies constant tension on a glass capillary tube and eventually breaks it while heating it; this produces a very fine point on the capillary tube.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>http://faculty.plattsburgh.edu/donald.slish/Puller1.html</obo:IAO_0000119>
<rdfs:label>electrode puller</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000956 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000956">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_handedness</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/PATO_0002201"/>
<rdfs:label>obsolete_handedness</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000957 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000957">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000944"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000938"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0002201"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>self reported handedness assessment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An assay where a person makes a statement that indicates what handedness he has from a choice of different categories.</obo:IAO_0000115>
<rdfs:label>self reported handedness assessment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000959 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000959">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000932"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000372"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600014"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>vibrotome</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A preparation device that uses a vibrating razor blade to cut through tissue.</obo:IAO_0000115>
<rdfs:label>vibrotome</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000960 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000960">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
<obo:IAO_0000111>reagent application function</obo:IAO_0000111>
<obo:IAO_0000112>An automatic tissue processor automatically applies antibodies and buffers to histological tissue preparations.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A function that is realized when a reagent is automatically added to some research material.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Nicole Vasilevsky, Matthew Brush</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Nicole Vasilevsky, Matthew Brush</obo:IAO_0000119>
<obo:IAO_0000232>4/10/2011: It is unclear if we need / want this, or what this is supposed to be for. Lots of the functions we have are reagent specific. Will this only confuse people?</obo:IAO_0000232>
<rdfs:label>reagent application function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000961 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000961">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000960"/>
<obo:IAO_0000111>addition of molecular tracer function</obo:IAO_0000111>
<obo:IAO_0000112>Immunohistochemical labeling of tissue sections by an autostainer staining system.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A reagent application function that is realized when a molecular tracer, such as an antibody or probe is automatically transferred to a biological specimen.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Nicole Vasilevsky, Matthew Brush</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Nicole Vasilevsky, Matthew Brush</obo:IAO_0000119>
<rdfs:label>addition of molecular tracer function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000962 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000962">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000005"/>
<obo:IAO_0000111>training objective</obo:IAO_0000111>
<obo:IAO_0000112>A training objective is fulfilled by e.g. a bioconductor tutorial which instructs the user in the use of a package</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An objective specification which is fulfilled by the provision of some training.</obo:IAO_0000115>
<obo:IAO_0000117>Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>training objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000963 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000963">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000009"/>
<obo:IAO_0000111>categorical label</obo:IAO_0000111>
<obo:IAO_0000112>The labels 'positive' vs. 'negative', or 'left handed', 'right handed', 'ambidexterous', or 'strongly binding', 'weakly binding' , 'not binding', or '+++', '++', '+', '-' etc. form scales of categorical labels.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A label that is part of a categorical datum and that indicates the value of the data item on the categorical scale.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>Bjoern Peters</obo:IAO_0000119>
<rdfs:label>categorical label</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000964 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000964">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>in live cell assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An assay in which a measurement is made by observing entities located in a live cell.</obo:IAO_0000115>
<rdfs:label>in live cell assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000965 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000965">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100051"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000927"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000112"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001472"/>
<obo:IAO_0000111>lyophilized specimen</obo:IAO_0000111>
<obo:IAO_0000112>freezing dried DNA</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a specimen that is output of a lyophilization storage process in which specimen is lyophilized for storage.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_589 freeze_dried_sample</obo:IAO_0000119>
<rdfs:label>lyophilized specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000966 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000966">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100026"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000086"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0001421"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>in live organism assay</obo:IAO_0000111>
<obo:IAO_0000112>Measuring the rate in which cells that are pulsed with a peptide are killed inside a mouse by peptide specific cytotoxic T cells.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay in which a measurement is made by observing entities located in an organism.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000118>in vivo assay</obo:IAO_0000118>
<rdfs:label>in live organism assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000967 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000967">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000968"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000370"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<obo:IAO_0000111>container</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A device that can be used to restrict the location of material entities over time</obo:IAO_0000115>
<obo:IAO_0000116>03/21/2010: Added to allow classification of children (similar to what we want to do for 'measurement device'. Lookint at what classifies here, we may want to reconsider a contain function assigned to a part of an entity is necessarily also a function of the whole (e.g. is a centrifuge a container because it has test tubes as parts?)</obo:IAO_0000116>
<obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
<rdfs:label>container</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000968 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000968">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
</owl:Restriction>
</rdfs:subClassOf>
<owl:disjointWith>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000086"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:disjointWith>
<obo:IAO_0000111>device</obo:IAO_0000111>
<obo:IAO_0000112>A voltmeter is a measurement device which is intended to perform some measure function.</obo:IAO_0000112>
<obo:IAO_0000112>An autoclave is a device that sterlizes instruments or contaminated waste by applying high temperature and pressure.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A material entity that is designed to perform a function in a scientific investigation, but is not a reagent.</obo:IAO_0000115>
<obo:IAO_0000116>2012-12-17 JAO: In common lab usage, there is a distinction made between devices and reagents that is difficult to model. Therefore we have chosen to specifically exclude reagents from the definition of "device", and are enumerating the types of roles that a reagent can perform.
2013-6-5 MHB: The following clarifications are outcomes of the May 2013 Philly Workshop. Reagents are distinguished from devices that also participate in scientific techniques by the fact that reagents are chemical or biological in nature and necessarily participate in some chemical interaction or reaction during the realization of their experimental role. By contrast, devices do not participate in such chemical reactions/interactions. Note that there are cases where devices use reagent components during their operation, where the reagent-device distinction is less clear. For example:
(1) An HPLC machine is considered a device, but has a column that holds a stationary phase resin as an operational component. This resin qualifies as a device if it participates purely in size exclusion, but bears a reagent role that is realized in the running of a column if it interacts electrostatically or chemically with the evaluant. The container the resin is in (“the column”) considered alone is a device. So the entire column as well as the entire HPLC machine are devices that have a reagent as an operating part.
(2) A pH meter is a device, but its electrode component bears a reagent role in virtue of its interacting directly with the evaluant in execution of an assay.
(3) A gel running box is a device that has a metallic lead as a component that participates in a chemical reaction with the running buffer when a charge is passed through it. This metallic lead is considered to have a reagent role as a component of this device realized in the running of a gel.
In the examples above, a reagent is an operational component of a device, but the device itself does not realize a reagent role (as bearing a reagent role is not transitive across the part_of relation). In this way, the asserted disjointness between a reagent and device holds, as both roles are never realized in the same bearer during execution of an assay.</obo:IAO_0000116>
<obo:IAO_0000117>PERSON: Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000118>instrument</obo:IAO_0000118>
<obo:IAO_0000119>OBI development call 2012-12-17.</obo:IAO_0000119>
<rdfs:label>device</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000969 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000969">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
<obo:IAO_0000111>dose specification</obo:IAO_0000111>
<obo:IAO_0000112>a protocol specifying to administer 1 ml of vaccine to a mouse</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a directive information entity that describes the dose that will be administered to a target</obo:IAO_0000115>
<rdfs:label>dose specification</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000970 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000970">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200000"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000004"/>
<owl:minCardinality rdf:datatype="http://www.w3.org/2001/XMLSchema#nonNegativeInteger">1</owl:minCardinality>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>scalar score from composite inputs</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A measurement datum which is the result of combining multiple datum. For example, a mean or summary score.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">JT: We included this because we wanted to talk about an output from a questionnaire that summarized the answers to the questionnaire, but which was not actually the answer to any single question.</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Person: Jessica Turner</obo:IAO_0000117>
<obo:IAO_0000118>questionaire score</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">Person: Jessica Turner</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">JZ: can we defined it logically as the output of some data transformation, like aggragate data transformation?</obo:IAO_0000232>
<rdfs:label>scalar score from composite inputs</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000971 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000971">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001472"/>
<obo:IAO_0000111>fresh specimen</obo:IAO_0000111>
<obo:IAO_0000112>a liver freshly removed from a rat</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a specimen that is output of a specimen creation process used for an investigation without storage.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_730 fresh_sample</obo:IAO_0000119>
<rdfs:label>fresh specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000972 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000972">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_electrically powered device</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a processed material created to have a function and which requires electrical power to execute</obo:IAO_0000115>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_electrically powered device</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000973 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000973">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000109"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/SO_0000001"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>sequence data</obo:IAO_0000111>
<obo:IAO_0000112>example of usage: the representation of a nucleotide sequence in FASTA format used for a sequence similarity search.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A measurement datum that representing the primary structure of a macromolecule(it's sequence) sometimes associated with an indicator of confidence of that measurement.</obo:IAO_0000115>
<obo:IAO_0000117>Person:Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>GROUP: OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">sequence data</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000974 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000974">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_right handedness</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<rdfs:label>obsolete_right handedness</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000975 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000975">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001977"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000916"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003368"/>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001588"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001977"/>
<obo:IAO_0000111>cell-cell binding detection by flow cytometry assay</obo:IAO_0000111>
<obo:IAO_0000112>Staining a B cell with PE and staining a T cell with FITC, incubating them together with a peptide, and counting the number of co-stained conjugates.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A binding assay which uses a flow cytometer to detect pairs of cells that are bound to each other by staining them with different fluorescent labels.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>cell-cell binding detection by flow cytometry assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000976 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000976">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000938"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000221"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0002201"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000999"/>
<owl:someValuesFrom>
<owl:Class>
<owl:oneOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000958"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000979"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000998"/>
</owl:oneOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>handedness categorical measurement datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A datum used to record the answer to a self assessment of whether a person uses their left hand, right hand primarily or each hand equally</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000117>PERSON:Jessica Turner</obo:IAO_0000117>
<rdfs:label>handedness categorical measurement datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000977 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000977">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0302893"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100026"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000465"/>
</owl:unionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000806"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>paraffin storage</obo:IAO_0000111>
<obo:IAO_0000112></obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a storage process with input organism or anatomical entity and paraffin and output material embedded in paraffin for long term storage</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>UPenn Group</obo:IAO_0000119>
<rdfs:comment>need to specify paraffin or wax is one of specified input of the process</rdfs:comment>
<rdfs:label>paraffin storage</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000978 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000978">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>in container assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An assay in which a measurement is made by observing entities located in a container.</obo:IAO_0000115>
<rdfs:label>in container assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000980 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000980">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_protocol service provider role</obo:IAO_0000111>
<obo:IAO_0000112>DNA sequencing of a sample by a core lab which returns data to the consumer</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a service provider role which is realized by a servicer provider organization performing a protocol execution</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_protocol service provider role</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000981 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000981">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100051"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001003"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000112"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001472"/>
<obo:IAO_0000111>agar stab specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a specimen that is output of a process that cell culture inoculated into agar for long term storage.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_971 agar_stab</obo:IAO_0000119>
<rdfs:label>agar stab specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000982 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000982">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000398"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000397"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>computed tomography scanner</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An image acquisition device that generates a three-dimensional image of the inside of an object from a large series of two-dimensional X-ray images taken around a single axis of rotation.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000118>CT scanner</obo:IAO_0000118>
<obo:IAO_0000118>X-ray computed tomography scanner</obo:IAO_0000118>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/X-ray_computed_tomography</obo:IAO_0000119>
<rdfs:label>computed tomography scanner</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000983 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000983">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0600007"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000444"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0005022"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600007"/>
<obo:IAO_0000111>intranasal mucosal administration</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">The administration of a substance into the intranasal mucosis of an organism</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Melanie Courtot</obo:IAO_0000117>
<rdfs:label>intranasal mucosal administration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000984 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000984">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
<obo:IAO_0000111>dose</obo:IAO_0000111>
<obo:IAO_0000112>An organism has been injected 1ml of vaccine</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A measurement datum that measures the quantity of something that may be administered to an organism or that an organism may be exposed to. Quantities of nutrients, drugs, vaccines and toxins are referred to as doses.</obo:IAO_0000115>
<rdfs:label>dose</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000985 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000985">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000115"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000750"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000931"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000750"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000997"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>growth condition intervention design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design in which the independent variable is the environmental condition in which the specimen is growing</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>MO_588 growth_condition_design</obo:IAO_0000119>
<rdfs:label>growth condition intervention design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000986 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000986">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_DNA sequencing training service</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A training process with the objective to provide a trainee with the skill to run DNA sequencing experiments</obo:IAO_0000115>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_DNA sequencing training service</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000987 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000987">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_general scalar measurement datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000124"/>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_general scalar measurement datum</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000988 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000988">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete performing a diagnosis</obo:IAO_0000111>
<obo:IAO_0000112>Diagnosing that a patient has pneumonia based on information on measurements of temperature, sound of breathing, and patient complaining about a headache.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">The interpretation of the information available about bodily features (clinical picture) of a patient resulting in a diagnosis</obo:IAO_0000115>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/623</obo:IAO_0000233>
<rdfs:label>obsolete performing a diagnosis</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000989 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000989">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400116"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000415"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>PCR instrument</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A device that is used to amplify a single or few copies of a piece of DNA across several orders of magnitude, generating thousands to millions of copies of a particular DNA sequence.</obo:IAO_0000115>
<obo:IAO_0000116>03/21/2010: Added because it is unclear if the thermal cycler definition is intentionally broader than PCR instrument. Contacted Melanie and Trish about this. Definitions and use of alternative terms need to be made consistent.</obo:IAO_0000116>
<rdfs:label>PCR instrument</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000990 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000990">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400169"/>
<obo:IAO_0000111>electron microscope</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A microscope that produces an image of an object by targeting it with an electron beam</obo:IAO_0000115>
<rdfs:label>electron microscope</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000991 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000991">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000970"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000221"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0002201"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000004"/>
<owl:minCardinality rdf:datatype="http://www.w3.org/2001/XMLSchema#nonNegativeInteger">1</owl:minCardinality>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>Edinburgh score</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A score that measures the dominance of a person's right or left hand in everyday activities.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000117>Person:Jessica Turner</obo:IAO_0000117>
<obo:IAO_0000119>PMID:5146491#Oldfield, R.C. (1971). The assessment and analysis of handedness: The Edinburgh inventory. Neuropsychologia, 9, 97-113</obo:IAO_0000119>
<obo:IAO_0000119>WEB:http://www.cse.yorku.ca/course_archive/2006-07/W/4441/EdinburghInventory.html</obo:IAO_0000119>
<rdfs:label>Edinburgh score</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000992 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000992">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001904"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000107"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000626"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001904"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000941"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000947"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>DNA sequencing service</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A DNA sequencing process provided as a service - which is the realization of some DNA sequencing in which the service provider role is realized.</obo:IAO_0000115>
<obo:IAO_0000116>Eagle-i will supply better English definition</obo:IAO_0000116>
<rdfs:label>DNA sequencing service</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000993 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000993">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000005"/>
<obo:IAO_0000111>service provision objective</obo:IAO_0000111>
<obo:IAO_0000112>A sequencing centre has a service provision objective</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An objective which is fulfilled by the provision of some service e.g. a training service</obo:IAO_0000115>
<obo:IAO_0000117>Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>service provision objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000994 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000994">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0600007"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000422"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000444"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001638"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000426"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600007"/>
<obo:IAO_0000111>intravenous injection</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">is the injection of a material entity (bearing the administered substance role) into the vein (bearing the target role) of an organism using a syringe</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Melanie Courtot</obo:IAO_0000117>
<rdfs:label>intravenous injection</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000995 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000995">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000274"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000444"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100051"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>administration of material to specimen</obo:IAO_0000111>
<obo:IAO_0000112>Staining cells in a tissue slice with a dye.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The directed combination of a material entity with a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>Bjoern Peters</obo:IAO_0000119>
<rdfs:label>administration of material to specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000996 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000996">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
<obo:IAO_0000111>device creation objective</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">an objective which aims to create a device with a specified function</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>device creation objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000997 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000997">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000111>growth environment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The collection of material entities and their qualities that are located near a live organism, tissue or cell and can influence its growth.</obo:IAO_0000115>
<obo:IAO_0000116>Right now this may be incomplete. Should also cover e.g. sound, light as well.</obo:IAO_0000116>
<obo:IAO_0000117>PERSON:Richard Scheuermann, Jie Zheng, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>OBI group</obo:IAO_0000119>
<rdfs:label>growth environment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001000 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001000">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000310"/>
<obo:IAO_0000111>questionnaire</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A document with a set of printed or written questions with a choice of answers, devised for the purposes of a survey or statistical study.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">JT: It plays a role in collecting data that could be fleshed out more; but I'm thinking it is, in itself, an edited document.
JZ: based on textual definition of edited document, it can be defined as N&S. I prefer to leave questionnaire as a document now. We can add more restrictions in the future and use that to determine it is an edited document or not.</obo:IAO_0000116>
<obo:IAO_0000116>Need to clarify if this is a document or a directive information entity (or what their connection is))</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">PERSON: Jessica Turner</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">Merriam-Webster</obo:IAO_0000119>
<rdfs:label>questionnaire</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001001 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001001">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000944"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000991"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/OBI_0001004"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>Edinburgh handedness assay</obo:IAO_0000111>
<obo:IAO_0000112>Verdino (1998) Perceptual and Motor Skills. 86 (2): 476_8. (PMID: 9638746) uses this measure in an experimental study: "Individuals of extreme handedness based on the Edinburgh Handedness Inventory (laterality Quotients of +90 to +100 and -100 and +54; 50 each)"</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that uses a set of questions (the Edinburgh Handedness inventory) to generate a score that can be used to assess the dominance of a person's right or left hand in everyday activities. The inventory can be used by an observer assessing the person, or by a person self-reporting hand use. The latter method tends to be less reliable due to a person over-attributing tasks to the dominant hand.</obo:IAO_0000115>
<obo:IAO_0000117>Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000117>Gully Burns (orcid:0000-0003-1493-865X)</obo:IAO_0000117>
<obo:IAO_0000117>Jessica Turner</obo:IAO_0000117>
<obo:IAO_0000119>PMID:5146491</obo:IAO_0000119>
<obo:IAO_0000119>url:http://en.wikipedia.org/wiki/Edinburgh_Handedness_Inventory</obo:IAO_0000119>
<rdfs:label>Edinburgh handedness assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001002 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001002">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001034"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000401"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>Faraday cage</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device formed by conducting material or by a mesh of such material, that blocks out external static electric fields.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000118>Faraday shield</obo:IAO_0000118>
<obo:IAO_0000119>Wikipedia http://en.wikipedia.org/wiki/Faraday_cage</obo:IAO_0000119>
<obo:IAO_0000232>isolation function? HP</obo:IAO_0000232>
<rdfs:label>Faraday cage</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001003 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001003">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0302893"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100060"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000806"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>agar stab storage</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a storage process with input cell culture and agar and output agar stab for long time storage</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>UPenn Group</obo:IAO_0000119>
<rdfs:comment>need to specify that agar is one of input for this process</rdfs:comment>
<rdfs:label>agar stab storage</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001005 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001005">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001014"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000880"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000880"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000086"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000025478"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000025478"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000896"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>RNASE CL3 structure mapping assay</obo:IAO_0000111>
<obo:IAO_0000112>PMID:16453415</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A single-nucleotide-resolution ribonucleic acid structure mapping assay that determines nucleic acid secondary structure at a nucleotide resolution scale using RNAse CL3 as reagent and enzymatic probe.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>single nucleotide resolution mapping assay using RNAse CL3</obo:IAO_0000118>
<obo:IAO_0000119>RNA ontology</obo:IAO_0000119>
<rdfs:label>RNASE CL3 structure mapping assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001006 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001006">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001017"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_16991"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_33697"/>
</owl:unionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000885"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>CMCT structure mapping assay</obo:IAO_0000111>
<obo:IAO_0000112>PMID:2422386 and PMID:2446263</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A single-nucleotide-resolution nucleic acid structure mapping assay which uses CMCT as reagent and chemical probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>single nucleotide resolution mapping assay using CMCT probe</obo:IAO_0000118>
<obo:IAO_0000119>RNA ontology</obo:IAO_0000119>
<rdfs:label>CMCT structure mapping assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001007 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001007">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000101"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>image acquisition</obo:IAO_0000111>
<obo:IAO_0000112>Taking a polaroid picture of a patients skin lesion; Using a digital camera to take a picture of a gel</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A planned process that captures an image of an object.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000118>image acquisition</obo:IAO_0000118>
<rdfs:label>image creation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001008 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001008">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001017"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000880"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
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<obo:IAO_0000111>Rhodium DNA structure mapping assay</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A single-nucleotide-resolution nucleic acid structure mapping assay that determines nucleic acid secondary structure at a nucleotide resolution scale using Rhodium as reagent and chemical probe.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>single nucleotide resolution mapping assay using Rhodium probe</obo:IAO_0000118>
<obo:IAO_0000119>RNA ontology</obo:IAO_0000119>
<rdfs:label>Rhodium DNA structure mapping assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001019 -->
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<obo:IAO_0000111>RNA ADA I RNA structure mapping assay</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A single-nucleotide-resolution ribonucleic acid structure mapping assay that determines nucleic acid secondary structure at a nucleotide resolution scale using RNA adenosine deaminase I as reagent and enzymatic probe.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>single nucleotide resolution mapping assay using RNA adenosine deaminase I</obo:IAO_0000118>
<obo:IAO_0000119>RNA ontology</obo:IAO_0000119>
<rdfs:label>RNA ADA I RNA structure mapping assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001020 -->
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<obo:IAO_0000111>Lead structure mapping assay</obo:IAO_0000111>
<obo:IAO_0000112>PMID:2686708</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A single-nucleotide-resolution nucleic acid structure mapping assay that determines nucleic acid secondary structure at nucleotide resolution scale using lead as reagent and chemical probe</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>single nucleotide resolution mapping assay using Lead probe</obo:IAO_0000118>
<obo:IAO_0000119>RNA ontology</obo:IAO_0000119>
<rdfs:label>Lead structure mapping assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001021 -->
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<obo:IAO_0000111>RNASE T2 structure mapping assay</obo:IAO_0000111>
<obo:IAO_0000112>PMID:6207483</obo:IAO_0000112>
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<obo:IAO_0000115 xml:lang="en">A single-nucleotide-resolution ribonucleic acid structure mapping assay that determines nucleic acid secondary structure at a nucleotide resolution scale using RNAse T2 as reagent and enzymatic probe</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>single nucleotide resolution mapping assay using RNAse T2</obo:IAO_0000118>
<obo:IAO_0000119>RNA ontology</obo:IAO_0000119>
<rdfs:label>RNASE T2 structure mapping assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001022 -->
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<obo:IAO_0000111>gene dosage assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures changes in phenotype due to increased or decreased dosage of a single allele of a gene.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>David Osumi Sutherland</obo:IAO_0000119>
<rdfs:label>gene dosage assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001023 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001023">
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<obo:IAO_0000111>Fe-BABE RNA structure mapping assay</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 7862644</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A single-nucleotide-resolution ribonucleic acid structure mapping assay that determines nucleic secondary structure at a nucleotide resolution scale using Fe-BABE as reagent and chemical probe.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>single nucleotide resolution mapping assay using Fe-BABE probe</obo:IAO_0000118>
<obo:IAO_0000119>RNA ontology</obo:IAO_0000119>
<rdfs:label>Fe-BABE RNA structure mapping assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001024 -->
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<obo:IAO_0000111>RNASE U2 structure mapping assay</obo:IAO_0000111>
<obo:IAO_0000112>PMID:409999</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A single-nucleotide-resolution ribonucleic acid structure mapping assay that determines nucleic acid secondary structure at a nucleotide resolution scale using RNAase U2 as reagent and enzymatic probe</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>single nucleotide resolution mapping assay using RNAse U2</obo:IAO_0000118>
<obo:IAO_0000119>RNA ontology</obo:IAO_0000119>
<rdfs:label>RNASE U2 structure mapping assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001025 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001025">
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<obo:IAO_0000111>binding constant determination assay</obo:IAO_0000111>
<obo:IAO_0000112>Determination of KD value for an antibody binding a protein using a BIACORE assay.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A binding assay where the specified output is a binding constant</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Jason Greenbaum</obo:IAO_0000117>
<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>binding constant determination assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001026 -->
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<obo:IAO_0000111>NMIA RNA structure mapping assay</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 15796531</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A single-nucleotide-resolution ribonucleic acid structure mapping assay that determines nucleic acid secondary structure at the nucleotide resolution scale using NMIA as reagent and chemical probe</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>SHAPE mapping assay</obo:IAO_0000118>
<obo:IAO_0000118>single nucleotide resolution mapping assay using NMIA probe</obo:IAO_0000118>
<obo:IAO_0000119>RNA ontology</obo:IAO_0000119>
<rdfs:label>NMIA RNA structure mapping assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001027 -->
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<!-- http://purl.obolibrary.org/obo/OBI_0001031 -->
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<!-- http://purl.obolibrary.org/obo/OBI_0001036 -->
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<!-- http://purl.obolibrary.org/obo/OBI_0001039 -->
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<obo:IAO_0000112>PMID:10573122 and PMID: 18369975</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A single-nucleotide-resolution ribonucleic acid structure mapping assay that determines nucleic acid secondary structure at nucleotide resolution scale using intromolecular reactivity</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>RNA ontology</obo:IAO_0000119>
<rdfs:label>inline probing RNA structure mapping assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001040 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001040">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
<obo:IAO_0000111>current amplification function</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A current amplification function is an amplification function that increases the amplitude of a current.</obo:IAO_0000115>
<obo:IAO_0000117>EAGLE-I</obo:IAO_0000117>
<rdfs:label>current amplification function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001041 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001041">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
<obo:IAO_0000111>stabilization function</obo:IAO_0000111>
<obo:IAO_0000112></obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A stabilization function is a function that holds or isolates an entity such as an instrument or specimen steadfast or at an unfluctuating level or quantity.</obo:IAO_0000115>
<obo:IAO_0000117>EAGLE-I</obo:IAO_0000117>
<obo:IAO_0000118>isolation function</obo:IAO_0000118>
<rdfs:label>stabilization function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001042 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001042">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000383"/>
<obo:IAO_0000111>pump function</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a transfer unction where the transfer requires work to move the entity, often against a gradient.</obo:IAO_0000115>
<obo:IAO_0000117>EAGLE-I</obo:IAO_0000117>
<rdfs:label>pump function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001043 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001043">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000383"/>
<obo:IAO_0000111>cell transfer function</obo:IAO_0000111>
<obo:IAO_0000112>A cell harvester has a cell transfer function.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">is a transfer function that displaces cells from one place to another</obo:IAO_0000115>
<obo:IAO_0000117>EAGLE-I</obo:IAO_0000117>
<rdfs:label>cell transfer function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001044 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001044">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000368"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>angiograph</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that records the patterns of pulse waves inside blood vessels.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://medical-dictionary.thefreedictionary.com/angiograph</obo:IAO_0000119>
<rdfs:label>angiograph</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001045 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001045">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000383"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>capillary blotter</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that is used to transfer nucleic acids from agarose gels onto a membrane, based on the movement of buffer from a reservoir through the gel and the blotting membrane to a stack of dry blotting paper by capillary force. The molecules are carried to the blotting membrane on which they are adsorbed.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://www.biometra.de/</obo:IAO_0000119>
<rdfs:label>capillary blotter</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001046 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001046">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001034"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000379"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000401"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>bioreactor</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device or system that supports a biologically active environment.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Bioreactor</obo:IAO_0000119>
<rdfs:label>bioreactor</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001047 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001047">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>pH meter</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that is used to measure the pH (acidity or alkalinity) of a liquid.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/PH_meter</obo:IAO_0000119>
<rdfs:label>pH meter</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001048 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001048">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000398"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000397"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>digital camera</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An image acquisition device that takes video or still photographs, or both, digitally by recording images via an electronic image sensor.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Digital_camera</obo:IAO_0000119>
<rdfs:label>digital camera</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001049 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001049">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000383"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>chip spotting device</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device for dropping and immobilizing a solution of biomolecules, for example, nucleic acids such as probe DNA, mRNA, and peptide nucleic acid (PNA), and proteins on a DNA microarray surface to manufacture a DNA microarray.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>United States Patent 7416705</obo:IAO_0000119>
<rdfs:label>chip spotting device</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001050 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001050">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001114"/>
<obo:IAO_0000111>RNA extraction/purification instrument</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that is used to isolate and collect RNA for subsequent molecular analysis.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Erik Segerdell</obo:IAO_0000119>
<rdfs:label>RNA extraction/purification instrument</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001051 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001051">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001010"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000257"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16991"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001010"/>
<obo:IAO_0000111>DNA extract</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The output of an extraction process in which DNA molecules are purified in order to exclude DNA from organellas.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>Group: UPenn group</obo:IAO_0000119>
<rdfs:label>DNA extract</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001052 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001052">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400065"/>
<obo:IAO_0000111>two-photon laser/detector</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A light source used in fluorescence imaging that allows the imaging of living tissue up to a depth of 1 mm, based on the concept that two photons of low energy can excite a fluorophore in a quantum event, resulting in the emission of a fluorescence photon, typically at a higher energy than either of the two excitatory photons.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Two-photon_excitation_microscopy</obo:IAO_0000119>
<rdfs:label>two-photon laser/detector</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001053 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001053">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000932"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000372"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>electrophoresis system</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that moves charged particles through a medium by using an electric field induced by electrodes.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Category:Electrophoresis</obo:IAO_0000119>
<rdfs:label>electrophoresis system</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001054 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001054">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000376"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>PET synthesizer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that is used to produce targeted molecular pharmaceuticals for use in positron emission tomography.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Erik Segerdell</obo:IAO_0000119>
<rdfs:label>PET synthesizer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001055 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001055">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001079"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>spinning-disk confocal microscope</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A confocal microscope that uses a Nipkow disk, a mechanical, geometrically operating image scanning device.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Nipkow_disk</obo:IAO_0000119>
<rdfs:label>spinning-disk confocal microscope</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001056 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001056">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400113"/>
<obo:IAO_0000111>DNA synthesizer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An oligonucleotide synthesizer that is used to custom-build DNA molecules to contain a particular sequence of nucleotides.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://www.globalspec.com/LearnMore/Labware_Scientific_Instruments/Clinical_Research_Labware/DNA_Synthesizers</obo:IAO_0000119>
<rdfs:label>DNA synthesizer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001057 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001057">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001139"/>
<obo:IAO_0000111>high performance liquid chromatography instrument</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A liquid chromatography instrument that consists of a reservoir of mobile phase, a pump, an injector, a separation column, and a detector. The pump (rather than gravity) provides the higher pressure required to propel the mobile phase and analyte through the densely packed column.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/High_performance_liquid_chromatography</obo:IAO_0000119>
<rdfs:label>high performance liquid chromatography instrument</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001058 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001058">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>microplate reader</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A measurement device that detects biological, chemical or physical events of samples in microtiter plates.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Plate_reader</obo:IAO_0000119>
<rdfs:label>microplate reader</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001059 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001059">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001058"/>
<obo:IAO_0000111>ELISA microplate reader</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A microplate reader that is used for enzyme-linked immunosorbent assays (ELISA).</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Erik Segerdell</obo:IAO_0000119>
<rdfs:label>ELISA microplate reader</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001060 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001060">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000379"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>spot cutter</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A robotic device that is used to excise spots from gels.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Erik Segerdell</obo:IAO_0000119>
<rdfs:label>spot cutter</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001061 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001061">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000374"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000376"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>microwave synthesis system</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that is used to apply microwave irradiation to chemical reactions.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Microwave_chemistry</obo:IAO_0000119>
<rdfs:label>microwave synthesis system</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001062 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001062">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>densitometer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that measures the degree of darkness (the optical density) of a photographic or semitransparent material or of a reflecting surface.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Densitometer</obo:IAO_0000119>
<rdfs:label>densitometer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001063 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001063">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000379"/>
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</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000961"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>automatic staining machine</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that is used to automatically stain tissue sections on slides or tissue specimens.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Erik Segerdell</obo:IAO_0000119>
<rdfs:label>automatic staining machine</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001064 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001064">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000379"/>
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</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000960"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>automatic tissue processor</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device for processing histological tissue having a tissue carrier basket suspended from a turntable overlying a plurality of beakers suspended from a carrier plate. The turntable is raised, indexed, and lowered by a suitable driving mechanism to move the tissue basket sequentially through the beakers. Timers can each be programmed to control the movement of the turntable to provide various different cycles for processing the tissue. Some of the beakers are received in individual thermal baths to heat and control the temperature of the substances received in the beakers for treating the tissue.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>United States Patent 3762362</obo:IAO_0000119>
<rdfs:label>automatic tissue processor</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001065 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001065">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000940"/>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>stereo microscope</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An optical microscope that uses two separate optical paths with two objectives and two eyepieces to provide slightly different viewing angles to the left and right eyes.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Optical_microscope#Stereo_microscope</obo:IAO_0000119>
<rdfs:label>stereo microscope</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001066 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001066">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001135"/>
<obo:IAO_0000111>top loading balance</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A balance that consists of a metal plate on which to place an object and a digital readout of the measurement of its mass.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Erik Segerdell</obo:IAO_0000119>
<rdfs:label>top loading balance</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001067 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001067">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001036"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>perfusion station</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device or system in which perfusion units are integrated.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Erik Segerdell</obo:IAO_0000119>
<rdfs:label>perfusion station</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001068 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001068">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000398"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000397"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>SPECT scanner</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A nuclear medicine tomographic imaging device that uses gamma rays to provide 3D information, typically presented as cross-sectional slices through the specimen but with the ability to be freely reformatted or manipulated as required.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Single_photon_emission_computed_tomography</obo:IAO_0000119>
<rdfs:label>SPECT scanner</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001069 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001069">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000571"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:allValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000457"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400147"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:allValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">array manufacturer role</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a manufacturer role which is played by the person or organization that manufactured the array</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">MO_695 array_manufacturer</obo:IAO_0000119>
<rdfs:label xml:lang="en">array manufacturer role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001070 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001070">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>scintillation counter</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that is used to measure ionizing radiation.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Scintillation_counter</obo:IAO_0000119>
<rdfs:label>scintillation counter</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001071 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001071">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001079"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>programmable array microscope</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A confocal microscope that uses a programmable spatial light modulator for generating an arbitrary pattern of conjugate illumination and detection apertures.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>Verveer et al, Journal of Microscopy, vol. 189, pt. 3, pp. 192-8</obo:IAO_0000119>
<rdfs:label>programmable array microscope</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001072 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001072">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000967"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001034"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000370"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000379"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000387"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>cryostat</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device consisting of a vessel, similar in construction to a vacuum flask, that is used to maintain cold cryogenic temperatures. FIX THIS DEFINITION</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Cryostat</obo:IAO_0000119>
<rdfs:label>cryostat</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001073 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001073">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000379"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>microtome knife maker</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A glass cutting and breaking device that is used to produce glass knives used in ultramicrotomy.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Erik Segerdell</obo:IAO_0000119>
<rdfs:label>microtome knife maker</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001074 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001074">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001036"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>cryofixation device</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that is used for the fixation or stabilization of biological materials as the first step in specimen preparation for electron microscopy.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Cryofixation</obo:IAO_0000119>
<rdfs:label>cryofixation device</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001075 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001075">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000136"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002089"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000370"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000379"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>hybridization oven</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that creates an appropriate environment for nucleic acid hybridization.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Erik Segerdell</obo:IAO_0000119>
<rdfs:label>hybridization oven</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001076 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001076">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002089"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000370"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000379"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000401"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>incubator shaker</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An incubating device that provides shaking motion for biomedical applications (e.g., cell cultures).</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Erik Segerdell</obo:IAO_0000119>
<rdfs:label>incubator shaker</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001077 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001077">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000398"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000397"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>small-animal image acquisition device</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that is used to image small laboratory animals (e.g., rats and mice) in vivo.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Erik Segerdell</obo:IAO_0000119>
<rdfs:label>small-animal image acquisition device</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001078 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001078">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000398"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000397"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>infrared image acquisition device</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An image acquisition device that is responsive to an infrared emissive target within a given field of view.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>United States Patent 4107530</obo:IAO_0000119>
<rdfs:label>infrared image acquisition device</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001079 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001079">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400169"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>confocal microscope</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A microscope that is used to increase micrograph contrast and/or reconstruct three-dimensional images by using a spatial pinhole to eliminate out-of-focus light in specimens that are thicker than the focal plane.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Confocal_microscopy</obo:IAO_0000119>
<rdfs:label>confocal microscope</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001080 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001080">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>patch clamp device</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device used in electrophysiology that allows the study of single or multiple ion channels in cells.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Patch_clamp</obo:IAO_0000119>
<rdfs:label>patch clamp device</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001081 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001081">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000398"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000397"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>gel imaging system</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that is used to acquire images of laboratory gels.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Erik Segerdell</obo:IAO_0000119>
<rdfs:label>gel imaging system</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001082 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001082">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000932"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000372"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>protein separation apparatus</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that is used for the separation of proteins.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Erik Segerdell</obo:IAO_0000119>
<rdfs:label>protein separation apparatus</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001083 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001083">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001118"/>
<obo:IAO_0000111>multichannel electronic pipette</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A multichannel pipette that can be programmed by the user to aspirate a volume of liquid reagent or sample and dispense the aspirated volume or a series of aliquots in successive dispensing operations.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://www.faqs.org/patents/app/20090196797</obo:IAO_0000119>
<rdfs:label>multichannel electronic pipette</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001084 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001084">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000379"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>vitrification apparatus</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that is used to effect the transition of a substance into a glass.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Glass_transition</obo:IAO_0000119>
<rdfs:label>vitrification apparatus</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001085 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001085">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000398"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000397"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>radiography instrument</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An image acquisition device that uses ionizing electromagnetic radiation such as X-rays to view objects.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Medical_radiography</obo:IAO_0000119>
<rdfs:label>radiography instrument</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001086 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001086">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000368"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>radiation measurement device</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that consists of a radiosensitive detector and a means of recording the effects of radiation on the detector.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Erik Segerdell</obo:IAO_0000119>
<rdfs:label>radiation measurement device</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001087 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001087">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000375"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000379"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>lyophilizer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that is used to freeze dry material.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Freeze_drying</obo:IAO_0000119>
<rdfs:label>lyophilizer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001088 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001088">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000049"/>
<obo:IAO_0000111>tandem mass spectrometer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A mass spectrometer in which ions are subjected to two or more sequential stages of analysis (which may be separated spatially or temporally) according to the quotient mass/charge.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://goldbook.iupac.org/T06250.html</obo:IAO_0000119>
<rdfs:label>tandem mass spectrometer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001089 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001089">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>microhardness tester</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A hardness testing device that is used in light-optical microscopes.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>United States Patent 4611487</obo:IAO_0000119>
<rdfs:label>microhardness tester</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001090 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001090">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001058"/>
<obo:IAO_0000111>multimode microplate reader</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A microplate reader that can detect multiple types of absorbance, luminescence or fluorescence.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Erik Segerdell</obo:IAO_0000119>
<rdfs:label>multimode microplate reader</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001091 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001091">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001135"/>
<obo:IAO_0000111>mechanical balance</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A balance that is used to compare the weights of two bodies, to determine the difference in mass (or weight).</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://www.britannica.com/EBchecked/topic/49765/balance</obo:IAO_0000119>
<rdfs:label>mechanical balance</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001092 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001092">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400107"/>
<obo:IAO_0000111>computer cluster</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A group of linked computers, working together closely so that in many respects they form a single computer.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Cluster_(computing)</obo:IAO_0000119>
<rdfs:label>computer cluster</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001093 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001093">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000379"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>microtome knife sharpener</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that is used to sharpen knives used in microtomy.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Erik Segerdell</obo:IAO_0000119>
<rdfs:label>microtome knife sharpener</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001094 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001094">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000379"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>plate shaker</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that provides shaking motion for microplates.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Erik Segerdell</obo:IAO_0000119>
<rdfs:label>plate shaker</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001095 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001095">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>coagulation analyzer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device for automatically analyzing blood coagulation in a clinical laboratory.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>United States Patent 5439646</obo:IAO_0000119>
<rdfs:label>coagulation analyzer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001096 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001096">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400169"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>laser capture microdissection microscope</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A microscope that uses low-energy laser beams and special transfer film to lift single cells from a tissue.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://www.answers.com/topic/laser-capture-microdissection-microscope-in-medicine</obo:IAO_0000119>
<rdfs:label>laser capture microdissection microscope</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001097 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001097">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400112"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000379"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>liquid extraction robot</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A liquid handling device that provides automatic liquid extraction.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Erik Segerdell</obo:IAO_0000119>
<rdfs:label>liquid extraction robot</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001098 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001098">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000398"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000397"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>ultrasound machine</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that is used to visualize subcutaneous body structures including tendons, muscles, joints, vessels and internal organs.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Sonography</obo:IAO_0000119>
<rdfs:label>ultrasound machine</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001099 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001099">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000398"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000397"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>immunoblot scanner</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that is used for the imaging of immunoblots.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Erik Segerdell</obo:IAO_0000119>
<rdfs:label>immunoblot scanner</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001100 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001100">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400106"/>
<obo:IAO_0000111>microcentrifuge</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A type of centrifuge that is designed for small tubes (0.2 ml to 2.0 ml), has a compact design, and has a small footprint.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Laboratory_centrifuge</obo:IAO_0000119>
<rdfs:label>microcentrifuge</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001101 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001101">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001128"/>
<obo:IAO_0000111>electronic repeater pipette</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A micropipette that can be programmed by the user to aspirate a volume of liquid reagent or sample and dispense a series of aliquots in successive dispensing operations.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://www.faqs.org/patents/app/20090196797</obo:IAO_0000119>
<rdfs:label>electronic repeater pipette</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001102 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001102">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400115"/>
<obo:IAO_0000111>electron paramagnetic resonance spectrometer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An spectrophotometer that is used to investigate chemical species that have one or more unpaired electrons, such as organic and inorganic free radicals or inorganic complexes possessing a transition metal ion.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Electron_paramagnetic_resonance</obo:IAO_0000119>
<rdfs:label>electron paramagnetic resonance spectrometer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001103 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001103">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000379"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>rocker</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that provides three-dimensional motion for biomedical applications (e.g., gel trays).</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Erik Segerdell</obo:IAO_0000119>
<rdfs:label>rocker</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001104 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001104">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001135"/>
<obo:IAO_0000111>analytical balance</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A balance with weighing pan(s) inside a transparent enclosure that is used to measure mass to a very high degree of precision and accuracy.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Weighing_scale</obo:IAO_0000119>
<rdfs:label>analytical balance</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001105 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001105">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400169"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>scanning force microscope</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A microscope that forms images of surfaces using a physical probe that scans the specimen.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Scanning_probe_microscopy</obo:IAO_0000119>
<rdfs:label>scanning force microscope</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001106 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001106">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001121"/>
<obo:IAO_0000111>pulsed-field gel electrophoresis system</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A gel electrophoresis system in which the gel matrix is subjected to an electric field that periodically changes direction.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Pulsed_field_gel_electrophoresis</obo:IAO_0000119>
<rdfs:label>pulsed-field gel electrophoresis system</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001107 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001107">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000379"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>tissue embedding station</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that is used to perform paraffin embedding of tissue specimens.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Erik Segerdell</obo:IAO_0000119>
<rdfs:label>tissue embedding station</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001108 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001108">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>nucleic acid sequencer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An device that is used to determine the order of nucleotides in nucleic acid sequences.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Erik Segerdell</obo:IAO_0000119>
<rdfs:label>nucleic acid sequencer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001109 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001109">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000398"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000397"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>bead array reader</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that is used to acquire and image bead array data.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Erik Segerdell</obo:IAO_0000119>
<rdfs:label>bead array reader</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001110 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001110">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000989"/>
<obo:IAO_0000111>real-time PCR machine</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An PCR instrument that enables both detection and quantification of one or more specific sequences in a DNA sample.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Real-time_polymerase_chain_reaction</obo:IAO_0000119>
<rdfs:label>real-time PCR machine</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001111 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001111">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000967"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001034"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000370"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000371"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000379"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>paraffin oven</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that is used for the warming of paraffin embedding medium.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Erik Segerdell</obo:IAO_0000119>
<rdfs:label>paraffin oven</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001112 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001112">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001034"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000371"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000379"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000946"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>autoclave</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that is used to sterilize equipment and supplies by subjecting them to high pressure steam at 121 C or more, typically for 15 to 20 minutes depending on the size of the load and the contents.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>J. Black, Microbiology, Prentice Hall (1993) pg. 334; http://en.wikipedia.org/wiki/Autoclave</obo:IAO_0000119>
<rdfs:label>autoclave</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001113 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001113">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000379"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>microplate washer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that is used to wash immunoassays in microwell strips and plates with professional accuracy. WHAT IS PROFESSIONAL ACCURACY??</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://www.articlesnatch.com/Article/Microplate-Readers-And-Washers-For-Laboratories/948037</obo:IAO_0000119>
<rdfs:label>microplate washer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001114 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001114">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000932"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000372"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>nucleic acid extraction/purification instrument</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that is used to isolate and collect nucleic acids (DNA or RNA) for subsequent molecular analysis.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Erik Segerdell</obo:IAO_0000119>
<rdfs:label>nucleic acid extraction/purification instrument</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001115 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001115">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001113"/>
<obo:IAO_0000111>ELISA microplate washer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A microplate washer that is used for enzyme-linked immunosorbent assays (ELISA).</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Erik Segerdell</obo:IAO_0000119>
<rdfs:label>ELISA microplate washer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001116 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001116">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000379"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>vacuum manifold</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that is used for the vacuum-driven processing of multiwell strips or plates, or spin columns. IS THIS AN INSTRUMENT? IS THE DEFINTION CORRECT - TO DISTRIBUTE PRESSURE EVENLY.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Erik Segerdell</obo:IAO_0000119>
<rdfs:label>vacuum manifold</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001117 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001117">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001114"/>
<obo:IAO_0000111>DNA extraction/purification instrument</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that is used to isolate and collect DNA for subsequent molecular analysis.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/DNA_extraction</obo:IAO_0000119>
<rdfs:label>DNA extraction/purification instrument</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001118 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001118">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000379"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>multichannel pipette</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pipetting system that has a plurality of tip fittings and is used for multi-well plate applications.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Erik Segerdell</obo:IAO_0000119>
<rdfs:label>multichannel pipette</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001119 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001119">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001043"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>cell harvester</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that is used to harvest cells from microplates and deposit samples on a filter mat. NOT AN INSTRUMENT?</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Erik Segerdell</obo:IAO_0000119>
<rdfs:label>cell harvester</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001120 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001120">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400143"/>
<obo:IAO_0000111>portable fluorometer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A compact fluorometer that can be carried or moved with ease.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Erik Segerdell</obo:IAO_0000119>
<rdfs:label>portable fluorometer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001121 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001121">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001053"/>
<obo:IAO_0000111>gel electrophoresis system</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An electrophoresis system in which an electric field is applied to a gel matrix</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Gel_electrophoresis</obo:IAO_0000119>
<rdfs:label>gel electrophoresis system</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001122 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001122">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>diffractometer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A measurement device for analyzing the structure of a material from the scattering pattern produced when a beam of radiation or particles (e.g. X rays or neutrons) interacts with it.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Diffractometer</obo:IAO_0000119>
<rdfs:label>diffractometer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001123 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001123">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000379"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>microdissection instrument</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that is used for the dissection of tissues under magnification.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://medical-dictionary.thefreedictionary.com/microdissection</obo:IAO_0000119>
<rdfs:label>microdissection instrument</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001124 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001124">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000379"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>micropipette puller</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that is used to fabricate glass micropipettes.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Micropipette</obo:IAO_0000119>
<rdfs:label>micropipette puller</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001125 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001125">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001079"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>laser scanning confocal microscope</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A confocal microscope that obtains high-resolution optical images with depth selectivity, in which a laser beam passes through a light source aperture and then is focused by an objective lens into a small (ideally diffraction limited) focal volume within or on the surface of a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Confocal_laser_scanning_microscopy</obo:IAO_0000119>
<rdfs:label>laser scanning confocal microscope</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001126 -->
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<obo:IAO_0000111>digital microscope</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A microscope that uses optics and a charge-coupled device (CCD) camera to output a digital image to a monitor.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Digital_microscope</obo:IAO_0000119>
<rdfs:label>digital microscope</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001127 -->
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<obo:IAO_0000111>freeze substitution system</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device or system for dehydrating and then chemically fixing electron microscopy samples at low temperatures in preparation for various treatments including embedding in resins.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>doi:10.1017/S143192760707866X</obo:IAO_0000119>
<rdfs:label>freeze substitution system</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001128 -->
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<obo:IAO_0000111>micropipette</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A microinjection device that is used to measure very small volumes of liquids.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://www.answers.com/topic/micropipette</obo:IAO_0000119>
<rdfs:label>micropipette</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001129 -->
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<obo:IAO_0000111>voltage clamp device</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that is used to measure the ion currents across the membrane of excitable cells, such as neurons, while holding the membrane voltage at a set level.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Voltage_clamp</obo:IAO_0000119>
<rdfs:label>voltage clamp device</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001130 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001034"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000370"/>
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<obo:IAO_0000111>vacuum oven</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that heats materials in a vacuum.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Erik Segerdell</obo:IAO_0000119>
<rdfs:label>vacuum oven</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001131 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001034"/>
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<obo:IAO_0000111>slide warmer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that is used to heat microscope slides.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Erik Segerdell</obo:IAO_0000119>
<rdfs:label>slide warmer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001132 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001132">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001053"/>
<obo:IAO_0000111>capillary electrophoresis instrument</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An electrophoresis system that is used to separate ionic species by their charge and frictional forces and mass.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Capillary_electrophoresis</obo:IAO_0000119>
<rdfs:label>capillary electrophoresis instrument</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001133 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001133">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000932"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000372"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>denaturing high-performance liquid chromatography instrument</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A high performance liquid chromatography instrument that employs temperature-dependent separation of DNA containing mismatched base pairs from PCR-amplified DNA fragments for chromatographic mutation analysis.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>doi:10.1385/1-59259-850-1:173</obo:IAO_0000119>
<rdfs:label>denaturing high-performance liquid chromatography instrument</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001134 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001134">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001121"/>
<obo:IAO_0000111>agarose gel electrophoresis system</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A gel electrophoresis system that is used to separate DNA or RNA molecules by size, achieved by moving negatively charged nucleic acid molecules through an agarose matrix with an electric field.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Agarose_gel_electrophoresis</obo:IAO_0000119>
<rdfs:label>agarose gel electrophoresis system</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001135 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001135">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
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<obo:IAO_0000111>balance</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A measuring instrument that is used to determine the weight or mass of an object.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Weighing_scale</obo:IAO_0000119>
<rdfs:label>balance</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001136 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001136">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
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<obo:IAO_0000111>surface plasmon resonance instrument</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A tool for measuring adsorption of material onto planar metal (typically gold and silver) surfaces or onto the surface of metal nanoparticles.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Surface_plasmon_resonance</obo:IAO_0000119>
<rdfs:label>surface plasmon resonance instrument</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001137 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001137">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
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<owl:Restriction>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
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<obo:IAO_0000111>protein sequencer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An device that is used to determine the order of amino acids in protein sequences.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Erik Segerdell</obo:IAO_0000119>
<rdfs:label>protein sequencer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001138 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001138">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
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<owl:Restriction>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000374"/>
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<obo:IAO_0000111>X-ray source</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that is used to generate X-rays.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Erik Segerdell</obo:IAO_0000117>
<obo:IAO_0000118>x-ray generator</obo:IAO_0000118>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/X-ray_generator</obo:IAO_0000119>
<rdfs:label>X-ray source</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001139 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001139">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000048"/>
<obo:IAO_0000111>liquid chromatography instrument</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A chromatography device that dissolves a mixture in liquid mobile phase to separate the analyte to be measured from other molecules in the mixture and allows it to be isolated</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Matthew Brush</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Matthew Brush</obo:IAO_0000119>
<rdfs:label>liquid chromatography instrument</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001140 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001140">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000025"/>
<obo:IAO_0000111 xml:lang="en">spike-in quality control role</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a reference substance role that is borne by a material entity with a known amount which is mixed into the evaluant of assays for quality control or data normalization purposes</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON: Chris Stoeckert, Jie Zheng, Bjoern Peter</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">MO_937 spike_quality_control</obo:IAO_0000119>
<rdfs:label xml:lang="en">spike-in quality control role</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001141 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001141">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000577"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000219"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
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<obo:IAO_0000111 xml:lang="en">individual organism identifier</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a CRID symbol used to distinguish one individual organism from another.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">MO_169 Individual</obo:IAO_0000119>
<rdfs:label xml:lang="en">individual organism identifier</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001142 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001142">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000025"/>
<rdfs:subClassOf>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001143"/>
</owl:Restriction>
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<obo:IAO_0000111 xml:lang="en">dye swap quality control role</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a reference substance role that is borne by a material entity used in a dye swap design experiment for quality control or data normalization purposes</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">MO_524 dye_swap_quality_control</obo:IAO_0000119>
<rdfs:label xml:lang="en">dye swap quality control role</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001143 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001143">
<owl:equivalentClass>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000924"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
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<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0600038"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001010"/>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33696"/>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000924"/>
<obo:IAO_0000111>labeled nucleic acid extract</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a labeled specimen that is the output of a labeling process and has grain labeled nucleic acid for detection of the nucleic acid in future experiments.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000118>labeled extract</obo:IAO_0000118>
<obo:IAO_0000119>MO_221 labeledExtract</obo:IAO_0000119>
<rdfs:label>labeled nucleic acid extract</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001144 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001144">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003142"/>
<obo:IAO_0000111 xml:lang="en">binding constant</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">The predicted or measured binding affinity of a peptide to a MHC molecule can be captured in the binding constants "IC50 = 12 nM" or "t 1/2 = 30 minutes".</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A quantitative binding datum that is expressed as a scalar number and a unit, which can be utilized in equations that model the binding process independent of the specific assay performed.</obo:IAO_0000115>
<obo:IAO_0000116>10/6/11 BP: The distinction between binding datum and binding constant is based on the later being part of an equation. That should be captured in the logical definition here, and used to make it to a defined class.</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">PERSON: Bjoern Peters, Randi Vita, Jason Greenbaum</obo:IAO_0000117>
<rdfs:label xml:lang="en">binding constant</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001145 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001145">
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003117"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/COB_0000080"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003117"/>
<obo:IAO_0000111>3D structure determination of bound molecular complex assay</obo:IAO_0000111>
<obo:IAO_0000112>Determination of a 3D structure of an antibody binding a protein by X-Ray crystallography, which identifies the specific binding site of the antibody.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A 3D molecular structure determination assay in which a complex of 2 or more molecular enties is characterized which provides information on their binding configuration.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>3D structure determination of bound molecular complex assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001146 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001146">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001181"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001588"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>binding assay</obo:IAO_0000111>
<obo:IAO_0000112>Determination of KD value for an antibody binding a protein using a BIACORE assay. Using plate bound antigen in an ELISA to determine if a mixture of serum antibodies bind the antigen. The following are NOT binding assays, as the desired output is not binding data: RNA microarray experiments to determine levels of gene expression. ChIP experiments to determine where in DNA a transcription factor binds. Using an IL-2 antibody on an ELISA plate to determine presence of IL-2 after stimulating a T cell culture.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An assay with the objective to characterize the disposition of two or more material entities to form a complex.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Jason Greenbaum</obo:IAO_0000117>
<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
<rdfs:label>binding assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001147 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001147">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100060"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100060"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">cell culture expansion</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a process that results in the increase of cell numbers</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">including grow of yeast and bacteria</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">MO_758 grow</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">BP:
add it as subclass of 'cell culturing'
JZ:
No 'cell culturing' in OBI
Has term 'cell co-culturing' and 'maintaining cell culture'. Don't think either of it fit. So leave the term under process.</obo:IAO_0000232>
<rdfs:label xml:lang="en">cell culture expansion</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001148 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001148">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600043"/>
<obo:IAO_0000111 xml:lang="en">gene knock out</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a genetic transformation that renders a gene non-functional, e.g. due to a point mutation, or the removal of all, or part of, the gene using recombinant methods.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">MO_771 gene_knock_out</obo:IAO_0000119>
<rdfs:label xml:lang="en">gene knock out</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001149 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001149">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600043"/>
<obo:IAO_0000111 xml:lang="en">gene knock in</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a genetic transformation that involves the insertion of a protein coding cDNA sequence at a particular locus in an organism's chromosome. Typically, this is done in mice since the technology for this process is more refined, and because mouse embryonic stem cells are easily manipulated. The difference between knock-in technology and transgenic technology is that a knock-in involves a gene inserted into a specific locus, and is a "targeted" insertion.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">MO_437 gene_knock_in</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">WEB: http://en.wikipedia.org/wiki/Gene_Knock-in</obo:IAO_0000119>
<rdfs:label xml:lang="en">gene knock in</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001150 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001150">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600043"/>
<obo:IAO_0000111 xml:lang="en">chromosomal substitution</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A genetic transformation in which all, or part, of a chromosome from a donor replaces that of the recipient. It does not include chromosome recombination. For single gene insertion, use the term 'gene knock in'.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">MO_995 chromosomal_substitution</obo:IAO_0000119>
<rdfs:label xml:lang="en">chromosomal substitution</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001151 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001151">
<owl:equivalentClass>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0302859"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000000"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600043"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:unionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<obo:IAO_0000111 xml:lang="en">genetically modified material</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a material entity, organism or cell, that is the output of a genetic transformation process.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON: Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">GROUP: OBI</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">term is proposed by BP on Oct 25, 2010 dev call</obo:IAO_0000232>
<rdfs:label xml:lang="en">genetically modified material</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001152 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001152">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600043"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600033"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_16991"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_33697"/>
</owl:unionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000053"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000444"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>transfection</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a genetic transformation which relies on the use of physical, electrical and chemical phenomena to introduce DNA or RNA into a cell</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_366 transfection</obo:IAO_0000119>
<rdfs:label xml:lang="en">transfection</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001153 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001153">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
<obo:IAO_0000111 xml:lang="en">genetic transformation objective</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a material transformation objective aims to create genetically modified organism or cell</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">Person: Jie Zheng</obo:IAO_0000119>
<obo:IAO_0000232>suggested to be added by BP and AR during Oct 25, 2010 dev call</obo:IAO_0000232>
<rdfs:label xml:lang="en">genetic transformation objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001154 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001154">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600043"/>
<obo:IAO_0000111 xml:lang="en">induced mutagenesis</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A genetic transformation that is the modification of the genetic material (either coding or non-coding) of an organism caused by mutagenic processes, compounds, or irradiation.</obo:IAO_0000115>
<obo:IAO_0000116>Label and definition were clarified as per https://github.com/obi-ontology/obi/issues/1366</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">MO_564 induced_mutation</obo:IAO_0000119>
<rdfs:label xml:lang="en">induced mutagenesis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001155 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001155">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
<obo:IAO_0000111>3D structural organization datum</obo:IAO_0000111>
<obo:IAO_0000112>The atom coordinates found in a PDB (Protein Data Bank) file, generated by X Ray crystallography or NMR.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A measurement datum that describes the structural orientation of a material entity in 3D space.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Jason Greenbaum, Randi Vita, Bjoern Peters</obo:IAO_0000117>
<rdfs:label>3D structural organization datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001156 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001156">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001167"/>
<obo:IAO_0000111 xml:lang="en">age since planting measurement datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An age measurement datum that is the result of the measurement of the age of an organism since planting, the process of placing a plant in media (e.g. soil) to allow it to grow, which excludes sowing.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_495 planting</obo:IAO_0000119>
<obo:IAO_0000232>Discussed by Jie and Chris, proposed to combine with different kinds of processes as initial time point. Proposed 'age measurement assay' is proceeded by some process. The process can be any kind of process defined in OBI. Think it is more flexible. However, it is hard to model due to lake of temporal predicates on Nov 15, 2010 dev call.
Term proposed by Bjoern on Nov 8, 2010 dev call
Supported by Alan on Nov 15, 2010 dev call</obo:IAO_0000232>
<rdfs:label xml:lang="en">age since planting measurement datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001157 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001157">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001167"/>
<obo:IAO_0000111 xml:lang="en">age since hatching measurement datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An age measurement datum that is the result of the measurement of the age of an organism since hatching, the process of emergence from an egg.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_745 hatching</obo:IAO_0000119>
<rdfs:label xml:lang="en">age since hatching measurement datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001158 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001158">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100026"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001167"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>age determination assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that determines the duration of part of the life of an organism, where the initial time point is the beginning of some transitional state (such as birth or when planted).</obo:IAO_0000115>
<obo:IAO_0000116>This assay measures time not developmental stage. we recognize that development takes different time periods under different conditions such as media / temperature. For example, age measurement assay of fly age, the output likes 28 days but not mid-life of age at room temperature.</obo:IAO_0000116>
<obo:IAO_0000117>Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000118>age measurement assay</obo:IAO_0000118>
<obo:IAO_0000119>OBI group</obo:IAO_0000119>
<rdfs:label>age determination assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001159 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001159">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001167"/>
<obo:IAO_0000111 xml:lang="en">age since egg laying measurement datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An age measurement datum that is the result of the measurement of the age of an organism since egg laying, the process of the production of egg(s) by an organism.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_767 egg laying</obo:IAO_0000119>
<rdfs:label xml:lang="en">age since egg laying measurement datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001160 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001160">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000005"/>
<obo:IAO_0000111 xml:lang="en">assay validation objective</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">an objective specification to check the accuracy or the quality of the results of an assay by comparison with independent results</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">GROUP: Penn Group</obo:IAO_0000119>
<rdfs:label xml:lang="en">assay validation objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001161 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001161">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001167"/>
<obo:IAO_0000111 xml:lang="en">age since germination measurement datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An age measurement datum that is the result of the measurement of the age of an organism since germination, the process consisting of physiological and developmental changes by a seed, spore, pollen grain (microspore), or zygote that occur after release from dormancy, and encompassing events prior to and including the first visible indications of growth.</obo:IAO_0000115>
<obo:IAO_0000116>Definition of germination comes from GO. However, the term is deprecated from GO now because it is a grouping term without biological significance.</obo:IAO_0000116>
<obo:IAO_0000117>PERSON:Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_590 germination</obo:IAO_0000119>
<rdfs:label xml:lang="en">age since germination measurement datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001162 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001162">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
<obo:IAO_0000111>validation by reverse transcription PCR design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a study design in which checks the accuracy or the quality of the result of an assay by comparing with reverse transcription PCR results</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_986 reverse_transcription_PCR_quality_control</obo:IAO_0000119>
<rdfs:label>validation by reverse transcription PCR design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001163 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001163">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001167"/>
<obo:IAO_0000111 xml:lang="en">age since eclosion measurement datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An age measurement datum that is the result of the measurement of the age of an organism since eclosion, the process of emergence of an adult insect from its pupa or cocoon.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_876 eclosion</obo:IAO_0000119>
<rdfs:label xml:lang="en">age since eclosion measurement datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001164 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001164">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001167"/>
<obo:IAO_0000111 xml:lang="en">age since sowing measurement datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An age measurement datum that is the result of the measurement of the age of an organism since sowing, the process of placing a seed or spore in some media with the intention to invoke germination.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_748 sowing</obo:IAO_0000119>
<rdfs:label xml:lang="en">age since sowing measurement datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001165 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001165">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001167"/>
<obo:IAO_0000111 xml:lang="en">age since coitus measurement datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An age measurement datum that is the result of the measurement of the age of an organism since coitus, the process of copulation that occurs during the process of sexual reproduction.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_783 coitus</obo:IAO_0000119>
<rdfs:label xml:lang="en">age since coitus measurement datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001166 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001166">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
<obo:IAO_0000111>validation by real time PCR design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a study design in which the accuracy or the quality of the result of an assay is checked by comparing with real time PCR results</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_434 real_time_PCR_quality_control</obo:IAO_0000119>
<rdfs:label>validation by real time PCR design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001167 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001167">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000416"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000221"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000011"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">age measurement datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A time measurement datum that is the result of measurement of age of an organism</obo:IAO_0000115>
<obo:IAO_0000116>note that we are currently defining subtypes of age measurement datum that specify when the age is relative to, e.g. planting, as we don't have adequate temporal predicates yet.
life of bearer doesn't imply organism
this assay measures time not developmental stage. we recognize that development can take different time periods under different conditions such as media / temperature
age as a quality is dubious; we plan to revisit
stages in development are currently handled with controlled vocabulary, such as 2-somite stage.</obo:IAO_0000116>
<obo:IAO_0000117>PERSON: Alan Ruttenberg, Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_178 Age</obo:IAO_0000119>
<obo:IAO_0000232>In MageTab file, we use
initialTimePoint (a process) + age (a number expected) + TimeUnit (definied in UO, such as year, hour, day, etc.)
Now we use the term label indicating the start time point of measuring the age, (number + TimeUnit) are expected instances of the class</obo:IAO_0000232>
<obo:IAO_0000232>discussed on Nov 15, dev call
All subtype will be defined by textual definition now.</obo:IAO_0000232>
<rdfs:label xml:lang="en">age measurement datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001168 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001168">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001167"/>
<obo:IAO_0000111 xml:lang="en">age since fertilization measurement datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An age measurement datum that is the result of the measurement of the age of an organism since fertilization, the process of the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote.</obo:IAO_0000115>
<obo:IAO_0000116>Definition of fertilization comes from GO.</obo:IAO_0000116>
<obo:IAO_0000117>PERSON:Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_701 fertilization</obo:IAO_0000119>
<rdfs:label xml:lang="en">age since fertilization measurement datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001169 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001169">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001167"/>
<obo:IAO_0000111 xml:lang="en">age since birth measurement datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An age measurement datum that is the result of the measurement of the age of an organism since birth, the process of emergence and separation of offspring from the mother.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_710 birth</obo:IAO_0000119>
<rdfs:label xml:lang="en">age since birth measurement datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001170 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001170">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002692"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000880"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000880"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000552"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000880"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0010467"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>reverse transcription polymerase chain reaction assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that determines the concentration of RNA in a sample in which an RNA strand is first reverse transcribed into its DNA complement (complementary DNA, or cDNA) using the enzyme reverse transcriptase, and the resulting cDNA is amplified using traditional or real-time PCR.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>Penn Group</obo:IAO_0000119>
<rdfs:label>reverse transcription polymerase chain reaction assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001171 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001171">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000416"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000039"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UO_0000003"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>half life datum (t 1/2)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The time it takes for 50% of a class of stochastic processes to occur.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000118>t 1/2</obo:IAO_0000118>
<obo:IAO_0000119>Bjoern Peters</obo:IAO_0000119>
<rdfs:label>half life datum (t 1/2)</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001172 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001172">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000573"/>
<obo:IAO_0000111>dose response curve</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A data item of paired values, one indicating the dose of a material, the other quantitating a measured effect at that dose. The dosing intervals are chosen so that effect values be interpolated by a plotting a curve.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters; Randi Vita</obo:IAO_0000117>
<rdfs:label>dose response curve</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001173 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001173">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000011"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000941"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000947"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>service</obo:IAO_0000111>
<obo:IAO_0000112>providing a training course for UCSD employees how to run a DNA sequencer; sequencing a DNA sample provided by a service consumer restricted to non-human samples; giving access to tissue samples in a biobank within OHSU; JAX shipping mice from their colony.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A planned process in which a service provider performs a task (i.e. a planned process) for a service consumer.</obo:IAO_0000115>
<obo:IAO_0000117>Carlo; Matt</obo:IAO_0000117>
<obo:IAO_0000119>OBI workshop San Diego 2011</obo:IAO_0000119>
<rdfs:label>service</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001174 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001174">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600007"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000319"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110022"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>passive immunization</obo:IAO_0000111>
<obo:IAO_0000112>Giving VIG (concentrated antibodies from vaccinated donors) to a patient that is infected with smallpox. Transferring epitope specific T cells from one mouse into another.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">The injection of immune effector material (antibodies, T cells or B cells) into an organism so that the organisms immune system gains its immune effector function to recognize specific antigens.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Bjoern Peters, Randi Vita, Jason Greenbaum</obo:IAO_0000117>
<obo:IAO_0000118>adoptive transfer</obo:IAO_0000118>
<rdfs:label>passive immunization</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001175 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001175">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000005"/>
<obo:IAO_0000111 xml:lang="en">selective organism creation objective</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">an objective specification to generate a population or type of organism within species that have some uniform behavioral, morphological, physiological, or genetic characteristics with similarly bred organisms.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>WEB: wikipedia
http://en.wikipedia.org/wiki/Cultivar
http://en.wikipedia.org/wiki/Ecotype
http://en.wikipedia.org/wiki/Strain_%28biology%29</obo:IAO_0000119>
<rdfs:label xml:lang="en">selective organism creation objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001176 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001176">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110015"/>
<obo:IAO_0000111>Individual epitope immunization in vivo</obo:IAO_0000111>
<obo:IAO_0000112>Injection of a peptide T cell epitope into a mouse</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An immunization in which an individual epitope is administered into a host organism.</obo:IAO_0000115>
<obo:IAO_0000116>3/16/11 BP: This should have as a logical definition the exclusion that the immunogen cannot be something beyond the epitope itself. I don't know if that is possible to do here.</obo:IAO_0000116>
<obo:IAO_0000117>PERSON:Bjoern Peters, Jason Greenbaum, Randi Vita</obo:IAO_0000117>
<rdfs:label>Individual epitope immunization in vivo</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001177 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001177">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0600047"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400103"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400103"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000880"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000880"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600028"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000880"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000973"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000845"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600047"/>
<obo:IAO_0000111>RNA sequencing assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that determines the sequence of an RNA molecule.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>Bjoern Peters</obo:IAO_0000119>
<rdfs:label>RNA sequencing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001178 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001178">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>efficacy of epitope intervention experiment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that tests if inducing an epitope specific immune response in an organism has an effect, such as the ability to prevent, treat or exacerbate diseases in the organism.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000118>efficacy of in vivo intervention</obo:IAO_0000118>
<rdfs:label>efficacy of epitope intervention experiment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001179 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001179">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001184"/>
<obo:IAO_0000111>epitope protection from infectious challenge experiment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An epitope protection experiment in which the ability of the epitope to protect the host from an infection is assessed.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000118>protection from infectious challenge</obo:IAO_0000118>
<rdfs:label>epitope protection from infectious challenge experiment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001180 -->
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<obo:IAO_0000111>half maximal effective concentration (EC50)</obo:IAO_0000111>
<obo:IAO_0000112>Determining the potentency of a drug / antibody / toxicant by measuring a graded dose response curve, and determining the concentration of the compound where 50% of its maximal effect is observed.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">half maximal effective concentration (EC50) is a scalar measurement datum corresponding to the concentration of a compound which induces a response halfway between the baseline and maximum after some specified exposure time.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters; Randi Vita</obo:IAO_0000117>
<obo:IAO_0000119>wikipedia</obo:IAO_0000119>
<rdfs:label>half maximal effective concentration (EC50)</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001181 -->
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<obo:IAO_0000111>binding datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A data item that states if two or more material entities have the disposition to form a complex, and if so, how strong that disposition is.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters; Randi Vita</obo:IAO_0000117>
<rdfs:label>binding datum</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001182 -->
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<obo:IAO_0000111>negative binding datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A categorical binding datum that states that there is no significant disposition of two or more entities to form a complex.</obo:IAO_0000115>
<rdfs:label>negative binding datum</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001183 -->
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<obo:IAO_0000111>epitope protection from tumor challenge experiment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An epitope protection experiment in which the ability of the epitope to protect the host from developing tumors is assessed.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000118>protection from tumor challenge</obo:IAO_0000118>
<rdfs:label>epitope protection from tumor challenge experiment</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001184 -->
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<obo:IAO_0000111>epitope protection experiment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An efficacy of epitope intervention experiment that tests the efficacy of inducing an immune epitope response to prevent disease in a host.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000118>protection from challenge</obo:IAO_0000118>
<rdfs:label>epitope protection experiment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001185 -->
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100026"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001175"/>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
<obo:IAO_0000111 xml:lang="en">selectively maintained organism</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An organism that is bred to have some uniform behavioral, morphological, physiological, or genetic characteristics with similarly bred organisms</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters, Helen Parkinson, Philippe Rocca-Serra, Jie Zheng, Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000118>cultivar</obo:IAO_0000118>
<obo:IAO_0000118>ecotype</obo:IAO_0000118>
<obo:IAO_0000118>strain</obo:IAO_0000118>
<obo:IAO_0000119>MO_9 StrainOrLine, MO_71 Ecotype, MO_124 Cultivar</obo:IAO_0000119>
<rdfs:label xml:lang="en">selectively maintained organism</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001186 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001186">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001179"/>
<obo:IAO_0000111>epitope protection from infectious challenge experiment based on pathogen burden</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An epitope protection from infectious challenge experiment in which the readout is a reduction in the presence of pathogens in the host compared to controls.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000118>burden after infectious challenge</obo:IAO_0000118>
<rdfs:label>epitope protection from infectious challenge experiment based on pathogen burden</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001187 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001187">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
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<obo:IAO_0000111>infectious agent detection assay</obo:IAO_0000111>
<obo:IAO_0000112>Culturing a sputum sample on agar medium to detect bacterial growth; Stain slices of liver from a mouse to count presence of infectious centers; PCR amplification using primers specific for influenza virus.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures the presence or amount of an infectious agent in an evaluant</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Jason Greenbaum</obo:IAO_0000117>
<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
<obo:IAO_0000117>Richard Scheuermann</obo:IAO_0000117>
<rdfs:label>infectious agent detection assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001188 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001188">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001178"/>
<obo:IAO_0000111>epitope disease exacerbation experiment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An efficacy of epitope intervention experiment that tests the ability of inducing an epitope immune response to increase the severity of an existing disease in the host.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000118>exacerbation assay</obo:IAO_0000118>
<rdfs:label>epitope disease exacerbation experiment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001189 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001189">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001184"/>
<obo:IAO_0000111>epitope protection experiment based on survival</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An epitope protection experiment that determines the success of the epitope intervention based on increased survival of the host.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000118>host survival after challenge</obo:IAO_0000118>
<rdfs:label>epitope protection experiment based on survival</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001190 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001190">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001178"/>
<obo:IAO_0000111>epitope treatment experiment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An epitope intervention experiment that tests the ability of inducing an epitope immune response to treat an existing disease in the host.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000118>decreased disease symptoms after treatment</obo:IAO_0000118>
<rdfs:label>epitope treatment experiment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001191 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001191">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000032"/>
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</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>half maximal inhibitory concentration (IC50)</obo:IAO_0000111>
<obo:IAO_0000112>Interpolating that at a dose of IC50=12 nM, half of the binding of a comptetitive ligand is inhibited.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Half maximal inhibitory concentration (IC50) is a scalar measurement datum that measures the effectiveness of a compound to competitively inhibit a given process, and corresponds to the concentration of the compound at which it reaches half of its maximum inhibitory effect.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters; Randi Vita</obo:IAO_0000117>
<obo:IAO_0000119>wikipedia</obo:IAO_0000119>
<rdfs:label>half maximal inhibitory concentration (IC50)</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001192 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001192">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001174"/>
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<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001174"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001176"/>
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</rdfs:subClassOf>
<obo:IAO_0000111>epitope specific immune intervention</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An administration in vivo to either actively or passively immunize an organism in order to induce a response against a specific immune epitope</obo:IAO_0000115>
<obo:IAO_0000117>Person: Bjoern Peters, Randi Vita, Jason Greenbaum</obo:IAO_0000117>
<rdfs:label>epitope specific immune intervention</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001193 -->
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<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0001816"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
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</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001816"/>
<obo:IAO_0000111>epitope specific cytokine production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A process of cytokine production by T cells resulting from the recognition of a T cell epitope.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB (QTT)</obo:IAO_0000119>
<obo:IAO_0000232>Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl</obo:IAO_0000232>
<rdfs:label>epitope specific cytokine production by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001194 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001194">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0600031"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
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<owl:Class>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0071604"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001264"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600031"/>
<obo:IAO_0000111>ELISPOT assay measuring epitope specific transforming growth factor-beta production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An enzyme-linked immunospot assay that detects transforming growth factor-beta production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>TGFb release|ELISPOT</obo:OBI_9991118>
<rdfs:label>ELISPOT assay measuring epitope specific transforming growth factor-beta production by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001195 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001195">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
<rdfs:subClassOf>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
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<owl:Class>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000750"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
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<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000116"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
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<obo:IAO_0000111>operator variation design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design that assesses the operator performance and relation to data consistency and quality.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_519 operator_variation_design</obo:IAO_0000119>
<rdfs:label>operator variation design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001196 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001196">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003115"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
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<owl:Class>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0071612"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
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</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001308"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003115"/>
<obo:IAO_0000111>cytometric bead array assay measuring epitope specific IP-10 production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometric bead array assay that detects IP-10 production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>CXCL10/IP-10 release|cytometric bead array</obo:OBI_9991118>
<rdfs:label>cytometric bead array assay measuring epitope specific IP-10 production by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001197 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001197">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000131"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>comparative genome hybridization by array design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design that detects genomic copy number variations using microarray technology.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_856 comparative_genome_hybridization_design</obo:IAO_0000119>
<rdfs:label>comparative genome hybridization by array design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001198 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001198">
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<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0032631"/>
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<obo:IAO_0000111>assay measuring epitope specific interleukin-27 production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A T cell epitope specific cytokine production assay that detects interleukin-27 production by T cells.</obo:IAO_0000115>
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<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>IL-27 release|biological activity</obo:OBI_9991118>
<rdfs:label>assay measuring epitope specific interleukin-27 production by T cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001199 -->
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<obo:IAO_0000111>in vivo design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design that is conducted entirely in a living organism, e.g. a compound treatment in a mouse model.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_454 in_vivo_design</obo:IAO_0000119>
<rdfs:label>in vivo design</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001200 -->
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<obo:IAO_0000115 xml:lang="en">A study design that classifies an individual or group of individuals on the basis of alleles, haplotypes, SNPs using high througput sequencing techniques.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_560 genotyping_design</obo:IAO_0000119>
<rdfs:label>genotyping by high throughput sequencing design</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001201 -->
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<obo:IAO_0000111>epitope specific tolerance induction by T cells</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A process of tolerance induction by T cells resulting from the recognition of a T cell epitope.</obo:IAO_0000115>
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<obo:IAO_0000119>IEDB (QTT)</obo:IAO_0000119>
<obo:IAO_0000232>Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl</obo:IAO_0000232>
<rdfs:label>epitope specific tolerance induction by T cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001202 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001202">
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<obo:IAO_0000111>innate behavior design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design in which the innate behavior of the organism is examined, e.g. path finding in bees.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_355 innate_behavior_design</obo:IAO_0000119>
<rdfs:label>innate behavior design</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001203 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000874"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001264"/>
<obo:IAO_0000111>detection of specific nucleic acids with complementary probes assay measuring epitope specific transforming growth factor-beta production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A detection of specific nucleic acid polymers with complementary probes that detects transforming growth factor-beta production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>TGFb release|RNA/DNA detection</obo:OBI_9991118>
<rdfs:label>detection of specific nucleic acids with complementary probes assay measuring epitope specific transforming growth factor-beta production by T cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001204 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001204">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400148"/>
<obo:IAO_0000111>SNP microarray</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A DNA microarray used to detect polymorphisms in DNA samples</obo:IAO_0000115>
<obo:IAO_0000117>Person: Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000119>EFO_0002703 SNP array</obo:IAO_0000119>
<rdfs:label>SNP microarray</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001205 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001205">
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<obo:IAO_0000111>cell component comparison design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design that compares samples from different cell components.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_1019 cell_component_comparison_design</obo:IAO_0000119>
<rdfs:label>cell component comparison design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001206 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001206">
<owl:equivalentClass>
<owl:Class>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0600031"/>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0032604"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
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</owl:Class>
</owl:someValuesFrom>
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</owl:someValuesFrom>
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</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001233"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600031"/>
<obo:IAO_0000111>ELISPOT assay measuring epitope specific granulocyte macrophage colony-stimulating factor production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An enzyme-linked immunospot assay that detects granulocyte macrophage colony stimulating factor production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>GM-CSF release|ELISPOT</obo:OBI_9991118>
<rdfs:label>ELISPOT assay measuring epitope specific granulocyte macrophage colony-stimulating factor production by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001207 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001207">
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<owl:Class>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0071608"/>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0071608"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001193"/>
<obo:IAO_0000111>epitope specific macrophage inflammatory protein-1 alpha production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A process of macrophage inflammatory protein-1 alpha production by T cells resulting from the recognition of a T cell epitope.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB (QTT)</obo:IAO_0000119>
<obo:IAO_0000232>Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl</obo:IAO_0000232>
<rdfs:label>epitope specific macrophage inflammatory protein-1 alpha production by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001208 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001208">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0042110"/>
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</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0042110"/>
<obo:IAO_0000111>epitope specific T cell activation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A process of T cell activation resulting from the recognition of a T cell epitope.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB (QTT)</obo:IAO_0000119>
<obo:IAO_0000232>Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl</obo:IAO_0000232>
<rdfs:label>epitope specific T cell activation</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001209 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001209">
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110129"/>
<obo:IAO_0000111>assay measuring epitope specific interleukin-10 production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A T cell epitope specific cytokine production assay that detects interleukin-10 production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>IL-10 release|biological activity</obo:OBI_9991118>
<rdfs:label>assay measuring epitope specific interleukin-10 production by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001210 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001210">
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<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003115"/>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001264"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003115"/>
<obo:IAO_0000111>cytometric bead array assay measuring epitope specific transforming growth factor-beta production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometric bead array assay that detects transforming growth factor-beta production by T cells</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>TGFb release|cytometric bead array</obo:OBI_9991118>
<rdfs:label>cytometric bead array assay measuring epitope specific transforming growth factor-beta production by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001211 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001211">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
<obo:IAO_0000111>ex vivo design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design where all or part of an organism is removed and studied in vitro, e.g. part of a mouse is removed and cultured in vitro. A cell culture with an established cell line is an in vitro experiment.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_808 ex_vivo_design</obo:IAO_0000119>
<rdfs:label>ex vivo design</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001212 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001212">
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<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0001806"/>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001806"/>
<obo:IAO_0000111>epitope specific type IV hypersensitivity by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A process of type IV hypersensitivity by T cells resulting from the recognition of a T cell epitope.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB (QTT)</obo:IAO_0000119>
<obo:IAO_0000232>Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl</obo:IAO_0000232>
<rdfs:label>epitope specific type IV hypersensitivity by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001214 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001214">
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<obo:IAO_0000111>normalization testing design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design that tests different normalization procedures.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_729 normalization_testing_design</obo:IAO_0000119>
<rdfs:label>normalization testing design</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001215 -->
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<obo:IAO_0000115 xml:lang="en">A flow cytometry assay that detects epitope specific perforin release by T cells.</obo:IAO_0000115>
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<obo:IAO_0000115 xml:lang="en">A T cell epitope specific cytokine production assay that detects interleukin-22 production by T cells.</obo:IAO_0000115>
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<obo:IAO_0000115 xml:lang="en">A T cell epitope specific cytokine production assay that detects interleukin-8 production by T cells.</obo:IAO_0000115>
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<!-- http://purl.obolibrary.org/obo/OBI_0001219 -->
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<obo:IAO_0000115 xml:lang="en">A process of chemokine (C-C motif) ligand 1 production by T cells resulting from the recognition of a T cell epitope.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
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<rdfs:label>epitope specific chemokine (C-C motif) ligand 1 production by T cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001220 -->
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<!-- http://purl.obolibrary.org/obo/OBI_0001221 -->
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<obo:IAO_0000111>ChIP-chip by SNP array assay</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A ChIP-ChIP assay in which immunoprecipitated chromatin is run on a SNP array to detect polymorphism specific DNA elements in the isolated chromatin</obo:IAO_0000115>
<obo:IAO_0000117>ArrayExpress production team</obo:IAO_0000117>
<obo:IAO_0000119>EFO:0002764</obo:IAO_0000119>
<rdfs:label>ChIP-chip by SNP array assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001222 -->
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<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An enzyme-linked immunosorbent assay that detects RANTES production by T cells.</obo:IAO_0000115>
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<obo:IAO_0000119>IEDB</obo:IAO_0000119>
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<rdfs:label>ELISA measuring epitope specific RANTES production by T cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001223 -->
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<obo:IAO_0000111>cytometric bead array assay measuring epitope specific interleukin-1 beta production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometric bead array assay that detects interleukin-1 beta production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>IL-1b release|cytometric bead array</obo:OBI_9991118>
<rdfs:label>cytometric bead array assay measuring epitope specific interleukin-1 beta production by T cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001225 -->
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<obo:IAO_0000112 xml:lang="en">genotype information 'C57BL/6J Hnf1a+/-' in this case, C57BL/6J is the genetic population background information</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a genetic characteristics information which is a part of genotype information that identifies the population of organisms</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">proposed and discussed on San Diego OBI workshop, March 2011</obo:IAO_0000116>
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<rdfs:label xml:lang="en">genetic population background information</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001226 -->
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<obo:IAO_0000111>environmental history design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design in which some aspect of the organism's environmental history is studied, such as exposure to teratogen, radiation, climate etc.</obo:IAO_0000115>
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<rdfs:label>environmental history design</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001227 -->
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<obo:IAO_0000115 xml:lang="en">An enzyme-linked immunospot assay that detects interleukin-6 production by T cells</obo:IAO_0000115>
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<obo:IAO_0000119>IEDB</obo:IAO_0000119>
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<!-- http://purl.obolibrary.org/obo/OBI_0001228 -->
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<!-- http://purl.obolibrary.org/obo/OBI_0001249 -->
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000131"/>
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<obo:IAO_0000111>RNAi profiling by array assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay in which double stranded RNA is synthesized with a sequence complementary to a gene(s) of interest and introduced into a cell or organism, where it is recognized as exogenous genetic material and activates the RNAi pathway resulting in knockdown of the transcripts and providing a means to study downstream changes in gene expression.</obo:IAO_0000115>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<obo:IAO_0000119>EFO:0001030</obo:IAO_0000119>
<rdfs:label>RNAi profiling by array assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001305 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001305">
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001364"/>
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<obo:IAO_0000111 xml:lang="en">genotype information</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Genotype information can be: Mus musculus wild type (in this case the genetic population background information is Mus musculus), C57BL/6J Hnf1a+/- (in this case, C57BL/6J is the genetic population background information and Hnf1a+/- is the allele information</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a genetic characteristics information that is about the genetic material of an organism and minimally includes information about the genetic background and can in addition contain information about specific alleles, genetic modifications, etc.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">discussed on San Diego OBI workshop, March 2011</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Group: OBI group</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">Group: OBI group</obo:IAO_0000119>
<rdfs:label xml:lang="en">genotype information</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001306 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001306">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33697"/>
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<obo:IAO_0000111>RNA stability design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design that examines the stability and/or decay of RNA transcripts.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_553 RNA_stability_design</obo:IAO_0000119>
<rdfs:label>RNA stability design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001307 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001307">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400148"/>
<obo:IAO_0000111>tiling microarray</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A DNA microarray which has short fragments of nucleic acid immobilized on a substrate. These are designed to cover the whole genome of the target species. Tiling arrays are used to determine genome binding in ChIP assays or to identify transcribed regions.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000118>genome tiling array</obo:IAO_0000118>
<obo:IAO_0000119>EFO_0002704: tiling array</obo:IAO_0000119>
<rdfs:label>tiling microarray</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001308 -->
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0071612"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110129"/>
<obo:IAO_0000111>assay measuring epitope specific IP-10 production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A T cell epitope specific cytokine production assay that detects IP-10 production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>CXCL10/IP-10 release|biological activity</obo:OBI_9991118>
<rdfs:label>assay measuring epitope specific IP-10 production by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001309 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001309">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000916"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0032616"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000916"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001251"/>
<obo:IAO_0000111>intracellular cytokine staining assay measuring epitope specific interleukin-13 production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A flow cytometry assay that detects interleukin-13 production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>IL-13 release|ICS</obo:OBI_9991118>
<rdfs:label>intracellular cytokine staining assay measuring epitope specific interleukin-13 production by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001310 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001310">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000268"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000750"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>species comparison design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design that assays differences between distinct species.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_675 species_design</obo:IAO_0000119>
<rdfs:label>species comparison design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001311 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001311">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000912"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001155"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0003120"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000039"/>
<owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/UO_0000019"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
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</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000912"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001999"/>
<obo:IAO_0000111>X-ray crystallography assay determining the 3D structure of a T cell epitope:MHC:TCR complex</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A X-ray crystallography 3D molecular structure determination assay that characterizes the 3-dimensional molecular structure of a T cell epitope:MHC:TCR complex.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>3D structure|x-ray crystallography|angstroms</obo:OBI_9991118>
<rdfs:label>X-ray crystallography assay determining the 3D structure of a T cell epitope:MHC:TCR complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001313 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001313">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001331"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>transcription profiling by RT-PCR design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design which aims to examine the transcriptome of a biological sample by reverse transcription PCR (RT-PCR).</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>Group: ArrayExpress production team</obo:IAO_0000119>
<rdfs:label>transcription profiling by RT-PCR design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001314 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001314">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0035399"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0035399"/>
<obo:IAO_0000111>epitope specific T cell enhancement of B cell mediated immune response</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A process of T cell enhancement of B cell mediated immune response resulting from the recognition of a T cell epitope.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB (QTT)</obo:IAO_0000119>
<obo:IAO_0000232>Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl</obo:IAO_0000232>
<rdfs:label>epitope specific T cell enhancement of B cell mediated immune response</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001315 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001315">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000661"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0071610"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
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</owl:someValuesFrom>
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</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000661"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001276"/>
<obo:IAO_0000111>ELISA measuring epitope specific chemokine (C-C motif) ligand 1 production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An enzyme-linked immunosorbent assay that detects chemokine (C-C motif) ligand 1 production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>CCL1/TCA-3 release|ELISA</obo:OBI_9991118>
<rdfs:label>ELISA measuring epitope specific chemokine (C-C motif) ligand 1 production by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001316 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001316">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0032625"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
</owl:Restriction>
</owl:intersectionOf>
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</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0032625"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001193"/>
<obo:IAO_0000111>epitope specific interleukin-21 production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A process of interleukin-21 production by T cells resulting from the recognition of a T cell epitope.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB (QTT)</obo:IAO_0000119>
<obo:IAO_0000232>Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl</obo:IAO_0000232>
<rdfs:label>epitope specific interleukin-21 production by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001317 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001317">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000916"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110124"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0003141"/>
</owl:Restriction>
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<rdfs:subClassOf>
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</owl:Restriction>
</owl:someValuesFrom>
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</rdfs:subClassOf>
<obo:IAO_0000111>flow cytometry assay measuring cell-cell binding of a T cell epitope:MHC:TCR complex</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A flow cytometry assay that measures the cell-cell binding of an epitope:MHC complex binding with a T cell receptor.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>T cell- APC binding|binding assay</obo:OBI_9991118>
<rdfs:label>flow cytometry assay measuring cell-cell binding of a T cell epitope:MHC:TCR complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001318 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001318">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001985"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100023"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400149"/>
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<obo:IAO_0000115 xml:lang="en">An enzyme-linked immunospot assay that detects epitope specific granzyme B release by T cells.</obo:IAO_0000115>
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<obo:IAO_0000119>IEDB</obo:IAO_0000119>
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<obo:IAO_0000115 xml:lang="en">An efficacy of T cell epitope intervention experiment that uses a tolerance induction intervention experiment.</obo:IAO_0000115>
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<obo:IAO_0000119>IEDB</obo:IAO_0000119>
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<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>CCL5/RANTES release|RNA/DNA detection</obo:OBI_9991118>
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<obo:IAO_0000115 xml:lang="en">A cytometric bead array assay that detects interleukin-4 production by T cells</obo:IAO_0000115>
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<obo:IAO_0000119>IEDB</obo:IAO_0000119>
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<!-- http://purl.obolibrary.org/obo/OBI_0001327 -->
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<obo:IAO_0000115 xml:lang="en">A T cell epitope specific cytokine production assay that detects lymphotoxin A production by T cells.</obo:IAO_0000115>
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<obo:IAO_0000119>IEDB</obo:IAO_0000119>
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<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
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<!-- http://purl.obolibrary.org/obo/OBI_0001329 -->
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<obo:IAO_0000111>family history design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design in which the family history such as traits, characteristics, susceptibility to disease is studied.</obo:IAO_0000115>
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<!-- http://purl.obolibrary.org/obo/OBI_0001330 -->
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<obo:IAO_0000115 xml:lang="en">An enzyme-linked immunosorbent assay that detects chemokine (C-X-C motif) ligand 9 production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>CXCL9/MIG release|ELISA</obo:OBI_9991118>
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<!-- http://purl.obolibrary.org/obo/OBI_0001331 -->
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<obo:IAO_0000115 xml:lang="en">A molecular feature identification objective that aims to characterize the abundance of transcripts</obo:IAO_0000115>
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<!-- http://purl.obolibrary.org/obo/OBI_0001332 -->
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<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
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<obo:IAO_0000115 xml:lang="en">A cytometric bead array assay that detects interleukin-13 production by T cells.</obo:IAO_0000115>
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<obo:IAO_0000119>IEDB</obo:IAO_0000119>
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<!-- http://purl.obolibrary.org/obo/OBI_0001350 -->
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<obo:IAO_0000115 xml:lang="en">A detection of specific nucleic acid polymers with complementary probes that detects interferon-gamma production by T cells.</obo:IAO_0000115>
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<!-- http://purl.obolibrary.org/obo/OBI_0001351 -->
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<obo:IAO_0000111>epitope specific tumor necrosis factor superfamily cytokine production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A process of tumor necrosis factor superfamily cytokine production by T cells resulting from the recognition of a T cell epitope.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB (QTT)</obo:IAO_0000119>
<obo:IAO_0000232>Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl</obo:IAO_0000232>
<rdfs:label>epitope specific tumor necrosis factor superfamily cytokine production by T cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001352 -->
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<obo:IAO_0000111 xml:lang="en">allele information</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">genotype information 'C57BL/6J Hnf1a+/-' in this case, Hnf1a+/- is the allele information</obo:IAO_0000112>
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<obo:IAO_0000115 xml:lang="en">a genetic alteration information that about one of two or more alternative forms of a gene or marker sequence and differing from other alleles at one or more mutational sites based on sequence. Polymorphisms are included in this definition.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">discussed on San Diego OBI workshop, March 2011</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_58 Allele</obo:IAO_0000119>
<rdfs:label xml:lang="en">allele information</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001353 -->
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<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometric bead array assay that detects tumor necrosis factor alpha production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
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<!-- http://purl.obolibrary.org/obo/OBI_0001354 -->
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<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An enzyme-linked immunospot assay that detects interleukin-17 production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>IL-17 release|ELISPOT</obo:OBI_9991118>
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<!-- http://purl.obolibrary.org/obo/OBI_0001356 -->
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<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>IFNb release|RNA/DNA detection</obo:OBI_9991118>
<rdfs:label>detection of specific nucleic acids with complementary probes assay measuring epitope specific interferon-beta production by T cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001357 -->
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<obo:IAO_0000111>detection of specific nucleic acids with complementary probes assay measuring epitope specific granulocyte macrophage colony-stimulating factor production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A detection of specific nucleic acid polymers with complementary probes that detects granulocyte macrophage colony stimulating factor production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>GM-CSF release|RNA/DNA detection</obo:OBI_9991118>
<rdfs:label>detection of specific nucleic acids with complementary probes assay measuring epitope specific granulocyte macrophage colony-stimulating factor production by T cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001358 -->
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<obo:IAO_0000111>post-transcriptional modification design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design in which a modification of the transcriptome, proteome (not genome) is made, for example RNAi, antibody targeting.</obo:IAO_0000115>
<obo:IAO_0000116>post transcription modification design? or more clear RNAi design / antibody targeting design? need to check the use cases</obo:IAO_0000116>
<obo:IAO_0000117>Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_392 cellular_modification_design</obo:IAO_0000119>
<rdfs:label>post-transcriptional modification design</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001359 -->
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<obo:IAO_0000111>transcription profiling by RT-PCR assay</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A transcription profiling assay that uses reverse transcription PCR (RT-PCR).</obo:IAO_0000115>
<obo:IAO_0000117>Anna Farne</obo:IAO_0000117>
<obo:IAO_0000119>EFO:0002943</obo:IAO_0000119>
<rdfs:label>transcription profiling by RT-PCR assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001362 -->
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<obo:IAO_0000111>epitope specific chemokine (C-C motif) ligand 4 production by T cells</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A process of chemokine (C-C motif) ligand 4 production by T cells resulting from the recognition of a T cell epitope.</obo:IAO_0000115>
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<rdfs:label>epitope specific chemokine (C-C motif) ligand 4 production by T cells</rdfs:label>
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<obo:IAO_0000111>assay measuring epitope specific interleukin-23 production by T cells</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A T cell epitope specific cytokine production assay that detects interleukin-23 production by T cells.</obo:IAO_0000115>
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<obo:IAO_0000119>IEDB</obo:IAO_0000119>
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<rdfs:label>assay measuring epitope specific interleukin-23 production by T cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001364 -->
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<obo:IAO_0000111 xml:lang="en">genetic alteration information</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">a genetic characteristics information that is about known changes or the lack thereof from the genetic background, including allele information, duplication, insertion, deletion, etc.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">proposed and discussed on San Diego OBI workshop, March 2011</obo:IAO_0000116>
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<rdfs:label xml:lang="en">genetic alteration information</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001365 -->
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<obo:IAO_0000115 xml:lang="en">A study design that aims to study the processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_810 cellular_process_design</obo:IAO_0000119>
<rdfs:label>cellular process design</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001366 -->
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<obo:IAO_0000115 xml:lang="en">A process of RANTES production by T cells resulting from the recognition of a T cell epitope.</obo:IAO_0000115>
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<rdfs:label>epitope specific RANTES production by T cells</rdfs:label>
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<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A detection of specific nucleic acid polymers with complementary probes that detects interleukin-10 production by T cells.</obo:IAO_0000115>
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<obo:IAO_0000119>IEDB</obo:IAO_0000119>
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<rdfs:label>detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-10 production by T cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001368 -->
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<obo:IAO_0000115 xml:lang="en">A cytometric bead array assay that detects tumor necrosis factor superfamily cytokine production by T cells.</obo:IAO_0000115>
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<obo:IAO_0000119>IEDB</obo:IAO_0000119>
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<!-- http://purl.obolibrary.org/obo/OBI_0001369 -->
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<obo:IAO_0000115 xml:lang="en">an allele information that is about the allele found most frequently in natural populations, or in standard laboratory stocks for a given organism.</obo:IAO_0000115>
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<!-- http://purl.obolibrary.org/obo/OBI_0001370 -->
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<obo:IAO_0000115 xml:lang="en">A flow cytometry assay that detects chemokine (C-C motif) ligand 4 production by T cells.</obo:IAO_0000115>
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<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>CCL4/MIP-1b release|ICS</obo:OBI_9991118>
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<!-- http://purl.obolibrary.org/obo/OBI_0001371 -->
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<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A process of granzyme B production by T cells resulting from the recognition of a T cell epitope.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB (QTT)</obo:IAO_0000119>
<obo:IAO_0000232>Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl</obo:IAO_0000232>
<rdfs:label>epitope specific granzyme B production by T cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001373 -->
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<obo:IAO_0000111>epitope specific interleukin-8 production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A process of interleukin-8 production by T cells resulting from the recognition of a T cell epitope.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB (QTT)</obo:IAO_0000119>
<obo:IAO_0000232>Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl</obo:IAO_0000232>
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<obo:IAO_0000117>James Malone</obo:IAO_0000117>
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<!-- http://purl.obolibrary.org/obo/OBI_0001394 -->
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<obo:IAO_0000115 xml:lang="en">A process of cytotoxic T cell degranulation resulting from the recognition of a T cell epitope.</obo:IAO_0000115>
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<!-- http://purl.obolibrary.org/obo/OBI_0001395 -->
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<!-- http://purl.obolibrary.org/obo/OBI_0001396 -->
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<!-- http://purl.obolibrary.org/obo/OBI_0001397 -->
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<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometric bead array assay that detects granulocyte colony stimulating factor production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>G-CSF release|cytometric bead array</obo:OBI_9991118>
<rdfs:label>cytometric bead array assay measuring epitope specific granulocyte colony stimulating factor production by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001398 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001398">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000113"/>
<obo:IAO_0000111 xml:lang="en">protein and DNA interaction identification objective</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A sequence feature identification objective that aims to characterize the interactions between protein and DNA which includes identification of transcription factor binding sites.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">MO_933 binding_site_identification_design</obo:IAO_0000119>
<rdfs:label xml:lang="en">protein and DNA interaction identification objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001399 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001399">
<owl:equivalentClass>
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</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0032626"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001193"/>
<obo:IAO_0000111>epitope specific interleukin-22 production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A process of interleukin-22 production by T cells resulting from the recognition of a T cell epitope.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB (QTT)</obo:IAO_0000119>
<obo:IAO_0000232>Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl</obo:IAO_0000232>
<rdfs:label>epitope specific interleukin-22 production by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001400 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001400">
<owl:equivalentClass>
<owl:Class>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
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<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Class>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0071706"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
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</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110129"/>
<obo:IAO_0000111>assay measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A T cell epitope specific cytokine production assay that detects tumor necrosis factor superfamily cytokine production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>TNF release|biological activity</obo:OBI_9991118>
<rdfs:label>assay measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001401 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001401">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000186"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>protocol optimization design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design where different protocols or protocol parameters are compared aims to find an optimized protocol</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_934 optimization_design</obo:IAO_0000119>
<rdfs:label>protocol optimization design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001402 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001402">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000913"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0032623"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000913"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001445"/>
<obo:IAO_0000111>promoter activity detection by reporter gene assay measuring epitope specific interleukin-2 production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A promoter activity detection by reporter gene assay that detects interleukin-2 production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>IL-2 release|reporter gene assay</obo:OBI_9991118>
<rdfs:label>promoter activity detection by reporter gene assay measuring epitope specific interleukin-2 production by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001403 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001403">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001425"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001398"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000750"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0042571"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>ChIP-chip design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design which aims to identify protein binding sites in genomic DNA by a combination of chromatin immunoprecipitation and DNA microarray (chip) assays.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000118>ChIP-on-chip design</obo:IAO_0000118>
<obo:IAO_0000119>MO_933 binding_site_identification_design</obo:IAO_0000119>
<rdfs:label>ChIP-chip design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001404 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001404">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/SO_0000001"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000058"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_33696"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">genetic characteristics information</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a data item that is about genetic material including polymorphisms, disease alleles, and haplotypes.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">MO_66 IndividualGeneticCharacteristics</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">MO definition:
The genotype of the individual organism from which the biomaterial was derived. Individual genetic characteristics include polymorphisms, disease alleles, and haplotypes.
examples in ArrayExpress
wild_type
MutaMouse (CD2F1 mice with lambda-gt10LacZ integration)
AlfpCre; SNF5 flox/knockout
p53 knock out
C57Bl/6 gp130lox/lox MLC2vCRE/+
fer-15; fem-1
df/df
pat1-114/pat1-114 ade6-M210/ade6-M216 h+/h+ (cells are diploid)</obo:IAO_0000232>
<rdfs:label xml:lang="en">genetic characteristics information</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001405 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001405">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003115"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0071608"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001333"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003115"/>
<obo:IAO_0000111>cytometric bead array assay measuring epitope specific macrophage inflammatory protein-1 alpha production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometric bead array assay that detects macrophage inflammatory protein-1 alpha production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>CCL3/MIP-1a release|cytometric bead array</obo:OBI_9991118>
<rdfs:label>cytometric bead array assay measuring epitope specific macrophage inflammatory protein-1 alpha production by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001406 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001406">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0032632"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110129"/>
<obo:IAO_0000111>assay measuring epitope specific interleukin-3 production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A T cell epitope specific cytokine production assay that detects interleukin-3 production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>IL-3 release|biological activity</obo:OBI_9991118>
<rdfs:label>assay measuring epitope specific interleukin-3 production by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001407 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001407">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0042110"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002055"/>
<obo:IAO_0000111>assay measuring epitope specific T cell activation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A T cell epitope dependent biological activity assay that detects T cell activation.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>activation|biological activity</obo:OBI_9991118>
<rdfs:label>assay measuring epitope specific T cell activation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001408 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001408">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000131"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>imprinting design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design where differences in genetic imprinting of maternally- and paternally-inherited chromosomes (e.g., due to in vivo differences in chemical modification and/or chromatin structure) are compared.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_914 imprinting_design</obo:IAO_0000119>
<rdfs:label>imprinting design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001409 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001409">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000219"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0007049"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>cell cycle design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design that assays events that occur in relation to the cell cycle, which is the period between the formation of a cell, by division of its mother cell and the time when the cell itself divides to form two daughter cells.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_822 cell_cycle_design</obo:IAO_0000119>
<rdfs:label>cell cycle design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001410 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001410">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000131"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>translation profiling design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design in which surface-bound, translationally competent ribosome complexes are used to generate a translation profile for mRNA, where mRNA may be a single molecular species, or a combination of species, including complex mixtures such as those found in the set of mRNAs isolated from a cell or tissue. One or more components of the surface-bound ribosome complex may be labeled at specific positions to permit analysis of multiple or single molecules for determination of ribosomal conformational changes and translation kinetics. Translation profiles are used as the basis for comparison of an mRNA or set of mRNA species. The translation profile can be used to determine such characteristics as kinetics of initiation, kinetic of elongation, identity of the polypeptide product, and the like. Analysis of translation profiles may be used to determine differential gene expression, optimization of mRNA sequences for expression, screening drug candidates for an effect on translation.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>Group: ArrayExpress production team</obo:IAO_0000119>
<rdfs:label>translation profiling design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001411 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001411">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000219"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<!-- http://purl.obolibrary.org/obo/OBI_0001412 -->
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<obo:IAO_0000115 xml:lang="en">A cytometric bead array assay that detects RANTES production by T cells.</obo:IAO_0000115>
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<!-- http://purl.obolibrary.org/obo/OBI_0001413 -->
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<obo:IAO_0000111>cell culture analyte detection bioassay measuring epitope specific interleukin-6 production by T cells</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A reporter cell line analyte detection bioassay that detects interleukin-6 production by T cells.</obo:IAO_0000115>
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<!-- http://purl.obolibrary.org/obo/OBI_0001414 -->
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<obo:IAO_0000111>assay measuring epitope specific interferon-gamma production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A T cell epitope specific cytokine production assay that detects interferon-gamma production by T cells.</obo:IAO_0000115>
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<obo:IAO_0000119>IEDB</obo:IAO_0000119>
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<rdfs:label>assay measuring epitope specific interferon-gamma production by T cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001415 -->
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<obo:IAO_0000111>epitope specific interleukin-9 production by T cells</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A process of interleukin-9 production by T cells resulting from the recognition of a T cell epitope.</obo:IAO_0000115>
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<rdfs:label>epitope specific interleukin-9 production by T cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001416 -->
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<obo:IAO_0000111>assay measuring epitope specific tumor necrosis factor alpha production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay of epitope specific tumor necrosis factor alpha production by T cells that detects tumor necrosis factor production.</obo:IAO_0000115>
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<obo:OBI_9991118>TNFa release|biological activity</obo:OBI_9991118>
<rdfs:label>assay measuring epitope specific tumor necrosis factor alpha production by T cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001417 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001403"/>
<obo:IAO_0000111>ChIP-chip by tiling array design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design which aims to identify protein binding sites in genomic DNA by a combination of chromatin immunoprecipitation and tiling microarray (chip) assays.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
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<rdfs:label>ChIP-chip by tiling array design</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001418 -->
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<obo:IAO_0000115 xml:lang="en">A study design that examines the relationship between the size of the administered dose and the extent of the response.</obo:IAO_0000115>
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<rdfs:label>dose response design</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001419 -->
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<obo:IAO_0000111>ChIP-chip by tiling array assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A ChIP-ChIP assay in which immunoprecipitated chromatin is run on a tiling array that covers stretches of DNA to to detect which elements in those stretches are present in the isolated chromatin</obo:IAO_0000115>
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<obo:IAO_0000119>EFO:0002762</obo:IAO_0000119>
<rdfs:label>ChIP-chip by tiling array assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001420 -->
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<obo:IAO_0000111>epitope specific helper T cell enhancement of T cell mediated immune response</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A process of helper T cell enhancement of T cell mediated immune response resulting from the recognition of a T cell epitope.</obo:IAO_0000115>
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<obo:IAO_0000119>IEDB (QTT)</obo:IAO_0000119>
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<rdfs:label>epitope specific helper T cell enhancement of T cell mediated immune response</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001421 -->
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<obo:IAO_0000115 xml:lang="en">A process of interferon-beta production by T cells resulting from the recognition of a T cell epitope.</obo:IAO_0000115>
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<obo:IAO_0000119>IEDB (QTT)</obo:IAO_0000119>
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<rdfs:label>epitope specific interferon-beta production by T cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001422 -->
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<obo:IAO_0000111>organism part comparison design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design that compares tissues, regions, organs within or between organisms</obo:IAO_0000115>
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<rdfs:label>organism part comparison design</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001423 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001436"/>
<obo:IAO_0000111>intracellular material detection measuring epitope specific granzyme B release by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A flow cytometry assay that detects epitope specific granzyme B release by T cells</obo:IAO_0000115>
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<obo:IAO_0000119>IEDB</obo:IAO_0000119>
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<rdfs:label>intracellular material detection measuring epitope specific granzyme B release by T cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001425 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001425">
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<obo:IAO_0000111>protein binding site identification design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design that investigates protein binding sites on nucleic acids.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_933 binding_site_identification_design</obo:IAO_0000119>
<rdfs:label>protein binding site identification design</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001426 -->
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<obo:IAO_0000111>sex comparison design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design that assays differences associated with an organism's sex, gender or mating type.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_575 sex_design</obo:IAO_0000119>
<rdfs:label>sex comparison design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001427 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001427">
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<obo:IAO_0000111>transcription profiling by tiling array design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design in which gene expression on a genome-wide basis is evaluated, without bias toward coding or noncoding regions, using tiling arrays containing oligonucleotides that are either overlapping or spaced at regular intervals.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_507 tiling_path_design</obo:IAO_0000119>
<rdfs:label>transcription profiling by tiling array design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001429 -->
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0048869"/>
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<obo:IAO_0000111>cell differentiation design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design that assays events associated with cell development or differentiation.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_892 development_or_differentiation_design</obo:IAO_0000119>
<rdfs:label>cell differentiation design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001430 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001430">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
<obo:IAO_0000111>transcription profiling design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design that identifies forms and abundance of transcripts in the genome.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_533 transcript_identification_design</obo:IAO_0000119>
<rdfs:label>transcription profiling design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001432 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001432">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
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</rdfs:subClassOf>
<obo:IAO_0000111>operon identification design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design that identifies locations and members of operons in a genome.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_772 operon_identification_design</obo:IAO_0000119>
<rdfs:label>operon identification design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001433 -->
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0032609"/>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000910"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001414"/>
<obo:IAO_0000111>radio immuno assay measuring epitope specific interferon-gamma production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A radio immuno assay that detects interferon-gamma production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>IFNg release|radio immuno assay (RIA)</obo:OBI_9991118>
<rdfs:label>radio immuno assay measuring epitope specific interferon-gamma production by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001435 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001435">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
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<obo:IAO_0000111>DNA methylation profiling by high throughput sequencing design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design in which the methylation state of DNA is determined and is compared between samples using high throughput sequencing technology.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>GROUP: ArrayExpress production team</obo:IAO_0000119>
<rdfs:label>DNA methylation profiling by high throughput sequencing design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001436 -->
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</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001269"/>
<obo:IAO_0000111>assay measuring epitope specific granzyme B release by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A T cell epitope specific cytotoxic T cell degranulation assay that detects granzyme B release by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>granzyme B release|biological activity</obo:OBI_9991118>
<rdfs:label>assay measuring epitope specific granzyme B release by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001437 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001437">
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<owl:Class>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000916"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
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</owl:someValuesFrom>
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</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000916"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001459"/>
<obo:IAO_0000111>intracellular cytokine staining assay measuring epitope specific chemokine (C-X-C motif) ligand 9 production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A flow cytometry assay that detects chemokine (C-X-C motif) ligand 9 production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>CXCL9/MIG release|ICS</obo:OBI_9991118>
<rdfs:label>intracellular cytokine staining assay measuring epitope specific chemokine (C-X-C motif) ligand 9 production by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001438 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001438">
<owl:equivalentClass>
<owl:Class>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0071607"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
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</owl:someValuesFrom>
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</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000661"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001456"/>
<obo:IAO_0000111>ELISA measuring epitope specific macrophage inflammatory protein-1 gamma production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An enzyme-linked immunosorbent assay that detects macrophage inflammatory protein-1 gamma production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>CCL9/MIP-1g release|ELISA</obo:OBI_9991118>
<rdfs:label>ELISA measuring epitope specific macrophage inflammatory protein-1 gamma production by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001439 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001439">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0035393"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0035393"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001193"/>
<obo:IAO_0000111>epitope specific chemokine (C-X-C motif) ligand 9 production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A process of chemokine (C-X-C motif) ligand 9 production by T cells resulting from the recognition of a T cell epitope.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB (QTT)</obo:IAO_0000119>
<obo:IAO_0000232>Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl</obo:IAO_0000232>
<rdfs:label>epitope specific chemokine (C-X-C motif) ligand 9 production by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001440 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001440">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
<obo:IAO_0000111>all pairs design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design in which all specimens are compared to every other specimen.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_565 all_pairs</obo:IAO_0000119>
<rdfs:label>all pairs design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001441 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001441">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000131"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>proteomic profiling by array design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design in which proteins in a sample are detected, quantified or otherwise analysed, through an array-based technology.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert, Jie Zheng, Dan Berrios</obo:IAO_0000117>
<obo:IAO_0000119>Group: ArrayExpress production team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/854</obo:IAO_0000233>
<rdfs:label>proteomic profiling by array design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001442 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001442">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000071"/>
<obo:IAO_0000111>q-value</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 20483222. Comp Biochem Physiol Part D Genomics Proteomics. 2008 Sep;3(3):234-42. Analysis of Sus scrofa liver proteome and identification of proteins differentially expressed between genders, and conventional and genetically enhanced lines.
"After controlling the false discovery rate (FDR</=0.1) using the Storey q value only four proteins (EPHX1, CAT, PAH, ST13) were shown to be differentially expressed between genders (Males/Females) and two proteins (SELENBP2, TAGLN) were differentially expressed between two lines (Transgenic/Conventional pigs)"</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A quantitative confidence value that measures the minimum false discovery rate that is incurred when calling that test significant.
To compute q-values, it is necessary to know the p-value produced by a test and possibly set a false discovery rate level.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERS:Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">FDR adjusted p-value</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">Adapted from several sources, including
http://.en/wikipedia.org/wiki/False_discovery_rate
http://svitsrv25.epfl.ch/R-doc/library/qvalue.html</obo:IAO_0000119>
<rdfs:label>q-value</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001444 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001444">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000113"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>genotyping design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design that classifies an individual or group of individuals on the basis of alleles, haplotypes, SNPs.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_560 genotyping_design</obo:IAO_0000119>
<rdfs:label>genotyping design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001445 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001445">
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0032623"/>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110129"/>
<obo:IAO_0000111>assay measuring epitope specific chemokine (C-X-C motif) ligand 9 production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A T cell epitope specific cytokine production assay that detects chemokine (C-X-C motif) ligand 9 production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>CXCL9/MIG release|biological activity</obo:OBI_9991118>
<rdfs:label>assay measuring epitope specific chemokine (C-X-C motif) ligand 9 production by T cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001460 -->
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<obo:IAO_0000111>genetic modification design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design in which an organism(s) is studied that has had genetic material removed, rearranged, mutagenized or added, such as in a knock out.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_447 genetic_modification_design</obo:IAO_0000119>
<rdfs:label>genetic modification design</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001461 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000661"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001436"/>
<obo:IAO_0000111>ELISA measuring epitope specific granzyme B release by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An enzyme-linked immunosorbent assay that detects epitope specific granzyme B release by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>granzyme B release|ELISA</obo:OBI_9991118>
<rdfs:label>ELISA measuring epitope specific granzyme B release by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001462 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001462">
<owl:equivalentClass>
<owl:Class>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0071612"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
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</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0071612"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001193"/>
<obo:IAO_0000111>epitope specific IP-10 production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A process of IP-10 production by T cells resulting from the recognition of a T cell epitope.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB (QTT)</obo:IAO_0000119>
<obo:IAO_0000232>Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl</obo:IAO_0000232>
<rdfs:label>epitope specific IP-10 production by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001463 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001463">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000424"/>
<rdfs:subClassOf>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400148"/>
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</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400148"/>
</owl:Restriction>
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<obo:IAO_0000111>transcription profiling by array assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A transcription profiling assay that uses array technology.</obo:IAO_0000115>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<obo:IAO_0000118>RNA profiling by array assay</obo:IAO_0000118>
<obo:IAO_0000119>EFO:0002768</obo:IAO_0000119>
<obo:IAO_0000233>https://sourceforge.net/p/obi/obi-terms/757/</obo:IAO_0000233>
<rdfs:label>transcription profiling by array assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001464 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001464">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000268"/>
</owl:Restriction>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001185"/>
</owl:Restriction>
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</owl:someValuesFrom>
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<obo:IAO_0000111>strain comparison design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design that assays differences between multiple strains, cultivars, serovars, isolates, lines from organisms of a single species.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_462 strain_or_line_design</obo:IAO_0000119>
<rdfs:label>strain comparison design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001465 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001465">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0071605"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110129"/>
<obo:IAO_0000111>assay measuring epitope specific monocyte chemotactic protein-1 production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A T cell epitope specific cytokine production assay that detects monocyte chemotactic protein-1 production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>CCL2/MCP-1 release|biological activity</obo:OBI_9991118>
<rdfs:label>assay measuring epitope specific monocyte chemotactic protein-1 production by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001466 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001466">
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<owl:Class>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000916"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0032615"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000916"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001391"/>
<obo:IAO_0000111>intracellular cytokine staining assay measuring epitope specific interleukin-12 production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A flow cytometry assay that detects interleukin-12 production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>IL-12 release|ICS</obo:OBI_9991118>
<rdfs:label>intracellular cytokine staining assay measuring epitope specific interleukin-12 production by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001467 -->
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_33208"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000086"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0001421"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
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</owl:Restriction>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001188"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001484"/>
<obo:IAO_0000111>in vivo assay measuring T cell epitope specific disease exacerbation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An efficacy of T cell epitope intervention experiment that uses a disease exacerbation in vivo intervention experiment.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>disease exacerbation|in vivo assay</obo:OBI_9991118>
<rdfs:label>in vivo assay measuring T cell epitope specific disease exacerbation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001468 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001468">
<owl:equivalentClass>
<owl:Class>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
</owl:Restriction>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>cell specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A specimen primarily composed of a cell or cells collected from a multicellular organism or a cell culture.</obo:IAO_0000115>
<obo:IAO_0000116>Discussed on obi call Jan 23, 2017. To improve cell specimen that include single cell specimen. Details see tracker: https://sourceforge.net/p/obi/obi-terms/828</obo:IAO_0000116>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng, Alexander Diehl</obo:IAO_0000117>
<obo:IAO_0000119>MO_612 cell</obo:IAO_0000119>
<rdfs:label>cell specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001469 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001469">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110125"/>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003368"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_1110037"/>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>monospecific T cell recognition assay measuring MHC ligand processing and presentation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A MHC ligand processing and presentation assay in which the presence of a specific ligand in an eluate is detected using the response of T cells that are known to be monospecific for that ligand as a readout.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>ligand presentation|T cell recognition</obo:OBI_9991118>
<rdfs:label>monospecific T cell recognition assay measuring MHC ligand processing and presentation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001470 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001470">
<owl:equivalentClass>
<owl:Class>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0097088"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0097088"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110193"/>
<obo:IAO_0000111>epitope specific interleukin-17F production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A process of interleukin-17F production by T cells resulting from the recognition of a T cell epitope.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB (QTT)</obo:IAO_0000119>
<obo:IAO_0000232>Date: 2011-06-27; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl</obo:IAO_0000232>
<rdfs:label>epitope specific interleukin-17F production by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001471 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001471">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001192"/>
<obo:IAO_0000111>T cell epitope specific immune intervention</obo:IAO_0000111>
<obo:IAO_0000112>Injecting a mouse with peptide SIINFEKL to induce a T cell response against the peptide</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An epitope specific immune intervention in which the induced response targets a T cell epitope</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>T cell epitope specific immune intervention</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001472 -->
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<obo:IAO_0000111>specimen with known storage state</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A specimen for which it is known whether it has been subjected to storage of a specified type.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_95 BiosourceType</obo:IAO_0000119>
<rdfs:label>specimen with known storage state</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001473 -->
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<obo:IAO_0000111>in vivo assay measuring T cell epitope specific protection after tumor burden challenge</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An in vivo assay measuring T cell epitope specific protection from tumor challenge using tumor burden.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>tumor burden after challenge|in vivo assay</obo:OBI_9991118>
<rdfs:label>in vivo assay measuring T cell epitope specific protection after tumor burden challenge</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001474 -->
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<obo:IAO_0000111 xml:lang="en">lowess group transformation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A lowess transformation where a potentially different normalization curve is generated and used for two or more groups (delineated by some criteria); criteria could include blocks (e.g. print-tip groups) on an array, or the day on which mass spectrometry was performed.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000119>MO_861 lowess_group_normalization</obo:IAO_0000119>
<rdfs:label xml:lang="en">lowess group transformation</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001475 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003460"/>
<obo:IAO_0000111>in vivo assay measuring T cell epitope specific protection from infectious challenge based on pathogen burden</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An in vivo assay measuring T cell epitope specific protection from pathogen challenge using pathogen burden.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>pathogen burden after challenge|in vivo assay</obo:OBI_9991118>
<rdfs:label>in vivo assay measuring T cell epitope specific protection from infectious challenge based on pathogen burden</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001476 -->
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003368"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0600047"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001146"/>
<obo:IAO_0000111>phage display binding assay</obo:IAO_0000111>
<obo:IAO_0000112>Using a commercial library of phages that produce random peptide sequences to infect E coli cells, and screening them for binding to a selecting antibody of unknown specificity. By iteratively using phages from selected E coli cells and repeating this process, phages encoding high affinity peptides for the antibody are selected, sequenced, and thereby the specificity of the antibody is elucidated.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A binding assay in which a collection of phages expressing a library of different peptides or protein fragnments is used to infect cells, followed by screening for cells that bind a protein of interest, and identifiying the sequence of infecting phages to determine a suitable binding partner.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>phage display binding assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001477 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001477">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200169"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200167"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">lowess transformation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A data transformation of normalizing ratio data by using a locally weighted polynomial regression (typically after a log transformation). The regression can be performed on log ratios resulting from the relation of two data sets versus the average log intensity data from the same two data sets or it can be performed on raw or log transformed values from one data set versus values from another. The goal could be to remove intensity-dependent dye-specific effects from the set of pair wise ratios. This method can be applied globally, or limited by one or more specified criteria.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000119>MO_720 lowess_normalization</obo:IAO_0000119>
<rdfs:label xml:lang="en">lowess transformation</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001478 -->
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_1110125"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003368"/>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110125"/>
<obo:IAO_0000111>mass spectrometry assay measuring MHC ligand processing and presentation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A MHC ligand processing and presentation assay that uses a mass spectrometry assay to identify eluted ligands</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>ligand presentation|mass spectrometry</obo:OBI_9991118>
<rdfs:label>mass spectrometry assay measuring MHC ligand processing and presentation</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001479 -->
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000477"/>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0100051"/>
<obo:IAO_0000111>specimen from organism</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that derives from an anatomical part or substance arising from an organism. Examples of tissue specimen include tissue, organ, physiological system, blood, or body location (arm).</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000118>tissue specimen</obo:IAO_0000118>
<obo:IAO_0000119>MO_954 organism_part</obo:IAO_0000119>
<rdfs:label>specimen from organism</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001480 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001480">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1000029"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>phage display library panning</obo:IAO_0000111>
<obo:IAO_0000112>Screening a libray of M13 phages displaying random peptide sequences for binding to the MHC molecule HLA-A*02:02 resulting in a subset of phages that encode peptides that bind.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Phage display library panning is a process in which a diverse collection of phages encoding peptides or proteins are screened and the ones encoding active peptides/proteins are selected in an iterative process similar to natural selection.</obo:IAO_0000115>
<obo:IAO_0000117>Jason Greenbaum, Randi Vita, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB, http://en.wikipedia.org/wiki/Phage_display</obo:IAO_0000119>
<rdfs:label>phage display library panning</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001481 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001477"/>
<obo:IAO_0000111 xml:lang="en">lowess global transformation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A lowess transformation where the same normalization curve is used for all members of the data set; e.g. Features on an array, picked spots on a gel, or measured metabolites in a sample.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000119>MO_692 lowess_global_normalization</obo:IAO_0000119>
<rdfs:label xml:lang="en">lowess global transformation</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001482 -->
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0071604"/>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000916"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001264"/>
<obo:IAO_0000111>intracellular cytokine staining assay measuring epitope specific transforming growth factor-beta production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A flow cytometry assay that detects transforming growth factor-beta production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>TGFb release|ICS</obo:OBI_9991118>
<rdfs:label>intracellular cytokine staining assay measuring epitope specific transforming growth factor-beta production by T cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001483 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001483">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600014"/>
<rdfs:subClassOf>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000639"/>
</owl:Restriction>
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<obo:IAO_0000111 xml:lang="en">cell collecting</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A planned process that collects cells from culture.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_982 harvest</obo:IAO_0000119>
<rdfs:label xml:lang="en">cell collecting</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001484 -->
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0003385"/>
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<obo:IAO_0000115 xml:lang="en">A cytometric bead array assay that detects granulocyte macrophage colony stimulating factor production by T cells.</obo:IAO_0000115>
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<!-- http://purl.obolibrary.org/obo/OBI_0001491 -->
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<obo:IAO_0000117>IEDB</obo:IAO_0000117>
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<!-- http://purl.obolibrary.org/obo/OBI_0001494 -->
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<obo:IAO_0000117>IEDB</obo:IAO_0000117>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000916"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001217"/>
<obo:IAO_0000111>intracellular cytokine staining assay measuring epitope specific interleukin-22 production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A flow cytometry assay that detects interleukin-22 production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>IL-22 release|ICS</obo:OBI_9991118>
<rdfs:label>intracellular cytokine staining assay measuring epitope specific interleukin-22 production by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001497 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001497">
<owl:equivalentClass>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001269"/>
<obo:IAO_0000111>assay measuring epitope specific perforin release by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A T cell epitope specific cytotoxic T cell degranulation assay that detects perforin release by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>perforin release|biological activity</obo:OBI_9991118>
<rdfs:label>assay measuring epitope specific perforin release by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001498 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001498">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000997"/>
<obo:IAO_0000111 xml:lang="en">atmosphere</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A growth environment pertaining to the atmospheric conditions that is used to culture or grow an organism.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_219 atmosphere</obo:IAO_0000119>
<rdfs:label xml:lang="en">atmosphere</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001499 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001499">
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001146"/>
<obo:IAO_0000111>binding assay using fluorescence detection</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A binding assay that uses fluorescence detection as an indicator of binding.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>binding assay using fluorescence detection</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001500 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001500">
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_1110037"/>
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</owl:Class>
</owl:someValuesFrom>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000064"/>
</owl:Restriction>
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</owl:Class>
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<obo:IAO_0000111>coelution assay measuring MHC ligand processing and presentation using T cell recognition of HPLC fractionated eluate compared to synthetic ligand</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A MHC ligand processing and presentation assay in which an HPL chromatography is run to separate an input mixture of ligands eluted from MHC into fractions. These fractions are tested for recognition by T cells and compared to the recognition of a synthetic ligand that is presumed to be the recognized epitope. Identical HPLC fractionation and T cell recognition patterns confirm that the specific ligand was presented by MHC molecules.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>ligand presentation|coelution</obo:OBI_9991118>
<rdfs:label>coelution assay measuring MHC ligand processing and presentation using T cell recognition of HPLC fractionated eluate compared to synthetic ligand</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001501 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001501">
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000053"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000018"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>fluorescence detection assay</obo:IAO_0000111>
<obo:IAO_0000112>Using a laser to stimulate a cell culture that was previously labeled with fluorescent antibodies to detect light emmission at a different wavelength in order to determine the presence of surface markers the antibodies are specific for.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay in which a material's fluorescence is determined.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>fluorescence detection assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001502 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001502">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0035944"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0035944"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>epitope specific perforin production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The production of perforin, an immune mediator molecule involved in T cell degranulation, resulting from the recognition of a T cell epitope.</obo:IAO_0000115>
<obo:IAO_0000116>Should be linked to a GO process, which will be requested by IEDB team. Along with granzyme B production, should be tied to T cell degranulation</obo:IAO_0000116>
<obo:IAO_0000117>PERSON: Bjoern Peters, Randi Vita</obo:IAO_0000117>
<rdfs:label>epitope specific perforin production by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001503 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001503">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001588"/>
<rdfs:subClassOf>
<owl:Class>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001588"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000016"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110119"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0042611"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
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</rdfs:subClassOf>
<obo:IAO_0000111>MHC protein complex binding to ligand</obo:IAO_0000111>
<obo:IAO_0000112>The peptide SIINFEKL binding to an empty murine H-2 Kb molecule to form a complex.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The process in which a ligand binds to an MHC molecule to form a stable complex.</obo:IAO_0000115>
<obo:IAO_0000116>6/13/11 BP: The disposition referenced is the one of the ligand to bind the molecule. This along with binding as a function / process needs to be figured out with GO which is inconsistent at this point.</obo:IAO_0000116>
<obo:IAO_0000117>PERSON: Bjoern Peters; Randi Vita</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>MHC protein complex binding to ligand</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001504 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001504">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">dissection</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A planned process that separates and isolates tissues for surgical purposes, or for the analysis or study of their structures.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>EFO_0003856 dissection</obo:IAO_0000119>
<obo:IAO_0000119>MO_374 dissect</obo:IAO_0000119>
<rdfs:label xml:lang="en">dissection</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001505 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001505">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000796"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600014"/>
<obo:IAO_0000111 xml:lang="en">purification</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A planned process to separate a material entity into different compositions of which one or more have are purified fractions that contain higher concentration of a desired component, while others contain impurities and are not of interest</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_406 purify</obo:IAO_0000119>
<rdfs:label xml:lang="en">purification</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001506 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001506">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100051"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000659"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100026"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000086"/>
<owl:someValuesFrom>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/PATO_0001421"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/PATO_0001422"/>
</owl:unionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>specimen with pre- or post-mortem status</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen that has been established to be taken from a live (pre-mortem) or dead (post-mortem) organism.</obo:IAO_0000115>
<obo:IAO_0000116>organizational term, used in description of specimen that is created from known pre- or post-mortem status</obo:IAO_0000116>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_84 OrganismStatus</obo:IAO_0000119>
<rdfs:label>specimen with pre- or post-mortem status</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001507 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001507">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001190"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0003414"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0003385"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_33208"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000086"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0001421"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001190"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001484"/>
<obo:IAO_0000111>in vivo assay measuring T cell epitope specific treatment of disease</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An efficacy of T cell epitope intervention experiment that detects a decrease in disease.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>decreased disease|in vivo assay</obo:OBI_9991118>
<rdfs:label>in vivo assay measuring T cell epitope specific treatment of disease</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001508 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001508">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000416"/>
<obo:IAO_0000111 xml:lang="en">sampling time measurement datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A time measurement datum when an observation is made or a sample is taken from a material as measured from some reference point.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">time point</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">MO_738 timepoint</obo:IAO_0000119>
<rdfs:label xml:lang="en">sampling time measurement datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001509 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001509">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_1110125"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000705"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003368"/>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110125"/>
<obo:IAO_0000111>Edman degradation assay measuring MHC ligand processing and presentation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A MHC ligand processing and presentation assay that uses Edman degradation to identify the eluted ligands</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>ligand presentation|Edman degradation</obo:OBI_9991118>
<rdfs:label>Edman degradation assay measuring MHC ligand processing and presentation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001510 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001510">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001478"/>
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<obo:IAO_0000117>IEDB</obo:IAO_0000117>
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<!-- http://purl.obolibrary.org/obo/OBI_0001511 -->
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<obo:IAO_0000117>IEDB</obo:IAO_0000117>
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<obo:IAO_0000115 xml:lang="en">A cytometric bead array assay that detects interleukin-17A production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
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<rdfs:label>cytometric bead array assay measuring epitope specific interleukin-17A production by T cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001513 -->
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<obo:IAO_0000111>radioactivity detection assay measuring competitive binding of a purified-MHC:ligand complex</obo:IAO_0000111>
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<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
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<rdfs:label>radioactivity detection assay measuring competitive binding of a purified-MHC:ligand complex</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001514 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001514">
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<obo:IAO_0000111>minimal inhibitory concentration</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A scalar measurement datum that indicates the lowest concentration at which a specific compound significantly inhibits a process from occurring compared to in the absence of the compound.</obo:IAO_0000115>
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<obo:IAO_0000117>PERSON:Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>Bjoern Peters, coordinated with Albert Goldfain</obo:IAO_0000119>
<rdfs:label>minimal inhibitory concentration</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001515 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001515">
<owl:equivalentClass>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001528"/>
<obo:IAO_0000111>material maintenance service</obo:IAO_0000111>
<obo:IAO_0000112>model organism colony maintanance</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A material processing service in which a service provider makes physical modifications to a specified input material, such that at least one of the specified outputs of this process is a modified version of a specified input material.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Carlo Torniai</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Matthew Brush</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Matthew Brush</obo:IAO_0000119>
<rdfs:comment>Here we need to go back to the defintoin of storage process. It has object specification which is material maintenance. Not necessareley a material maintenance is needed in a storage process.</rdfs:comment>
<rdfs:label>material maintenance service</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001516 -->
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<owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/UO_0000065"/>
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<obo:IAO_0000111>radioactivity detection assay measuring half maximal effective concentration [EC50] to determine direct binding of a cell-lysate-MHC:ligand complex</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A radioactivity detection assay that measures half maximal effective concentration (EC50) to detect the direct binding of a cell-lysate-MHC molecule with a ligand.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
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<rdfs:label>radioactivity detection assay measuring half maximal effective concentration [EC50] to determine direct binding of a cell-lysate-MHC:ligand complex</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001517 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001992"/>
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<obo:IAO_0000119>IEDB</obo:IAO_0000119>
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<rdfs:label>radioactivity detection assay measuring half maximal inhibitory concentration [IC50] to determine competitive binding of a cell-bound-MHC:ligand complex</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001518 -->
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<obo:IAO_0000111>epitope specific tumor necrosis factor (ligand) superfamily member 11 production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A process of tumor necrosis factor (ligand) superfamily member 11 production by T cells resulting from the recognition of a T cell epitope.</obo:IAO_0000115>
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<rdfs:label>epitope specific tumor necrosis factor (ligand) superfamily member 11 production by T cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001519 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001579"/>
<obo:IAO_0000111>fluorescence detection assay measuring direct binding of a cell-lysate-MHC:ligand complex</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A fluorescence detection assay that detects direct binding of a cell-lysate-MHC molecule with a ligand.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
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<rdfs:label>fluorescence detection assay measuring direct binding of a cell-lysate-MHC:ligand complex</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001520 -->
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<!-- http://purl.obolibrary.org/obo/OBI_0001521 -->
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http://www.pdb.org/pdb/download/downloadFile.do?fileFormat=pdb&compression=NO&structureId=3pe4</obo:IAO_0000112>
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<obo:IAO_0000115 xml:lang="en">A 3d structural organization datum capturing the results of X-ray crystallography or NMR experiment that is formatted as specified by the Protein Databank (http://www.wwpdb.org/docs.html). A PDB file can describe the structure of multiple molecules, each of which has a different chain identifier assigned.</obo:IAO_0000115>
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<!-- http://purl.obolibrary.org/obo/OBI_0001528 -->
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<!-- http://purl.obolibrary.org/obo/OBI_0001529 -->
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<!-- http://purl.obolibrary.org/obo/OBI_0001530 -->
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<!-- http://purl.obolibrary.org/obo/OBI_0001531 -->
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<!-- http://purl.obolibrary.org/obo/OBI_0001532 -->
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<!-- http://purl.obolibrary.org/obo/OBI_0001540 -->
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<obo:IAO_0000117>IEDB</obo:IAO_0000117>
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<rdfs:label>fluorescence detection assay measuring equilibrium dissociation constant [KD] to determine direct binding of a purified-MHC:ligand complex approximated by EC50</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001544 -->
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<obo:IAO_0000115 xml:lang="en">A radioactivity detection assay that measures equilibrium dissociation constant (KD) to detect the loss of binding of a known reference ligand to cell-lysate-MHC due to competition by the ligand under investigation.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
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<rdfs:label>radioactivity detection assay measuring equilibrium dissociation constant [KD] to determine competitive binding of a cell-lysate-MHC:ligand complex</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001545 -->
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<obo:IAO_0000111>intracellular cytokine staining assay measuring epitope specific macrophage inflammatory protein-1 alpha production by T cells</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A flow cytometry assay that detects macrophage inflammatory protein-1 alpha production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>CCL3/MIP-1a release|ICS</obo:OBI_9991118>
<rdfs:label>intracellular cytokine staining assay measuring epitope specific macrophage inflammatory protein-1 alpha production by T cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001546 -->
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<obo:IAO_0000111>comparative phenotypic assessment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Interpreting data from assays that evaluate the qualities or dispositions inhering in an organism or organism part and comparing it to data from other organisms to make a conclusion about a phenotypic difference</obo:IAO_0000115>
<obo:IAO_0000117>Philly workshop 2011</obo:IAO_0000117>
<obo:IAO_0000119>Philly workshop 2011</obo:IAO_0000119>
<obo:IAO_0000232>6/1/2012: We will utilize 'comparative qualities' once they are available in BFO2</obo:IAO_0000232>
<rdfs:label>comparative phenotypic assessment</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001547 -->
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<obo:IAO_0000111>material analysis service</obo:IAO_0000111>
<obo:IAO_0000112>Services performing DNA sequencing or Cell Analysis</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A service in which a service consumer provides some input material and a service provider performs some analysis of this material to generate data that is returned to the service consumer.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Carlo Torniai</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Matthew Brush</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Matthew Brush</obo:IAO_0000119>
<rdfs:label>material analysis service</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001548 -->
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<obo:IAO_0000111>equilibrium association constant (KA)</obo:IAO_0000111>
<obo:IAO_0000112>KA = 10^-12 M^-1 is the equilibirum association constant maximally found for antibody binding to haptens.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A binding constant defined as the ratio of koff over kon (off-rate of binding divided by on-rate)</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Bjoern Peters, Randi Vita</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
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<!-- http://purl.obolibrary.org/obo/OBI_0001549 -->
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<obo:IAO_0000111>radioactivity detection assay measuring equilibrium dissociation constant [KD] to determine competitive binding of a cell-bound-MHC:ligand complex</obo:IAO_0000111>
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<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
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<rdfs:label>radioactivity detection assay measuring equilibrium dissociation constant [KD] to determine competitive binding of a cell-bound-MHC:ligand complex</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001550 -->
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<!-- http://purl.obolibrary.org/obo/OBI_0001551 -->
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<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A service in which a service consumer receives the right to use a resource (instrument, database, software, etc) that is owned or managed by a service provider. Ownership of the accessed resource remains with the service provider during and after provision of service.</obo:IAO_0000115>
<obo:IAO_0000116>Need to come up wiht a proper logical defintion. One option woudl be to dfine provides_access_to property as shortcut of participants in a process.</obo:IAO_0000116>
<obo:IAO_0000117>PERSON: Carlo Torniai</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Matthew Brush</obo:IAO_0000117>
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<!-- http://purl.obolibrary.org/obo/OBI_0001552 -->
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<obo:IAO_0000111>intracellular cytokine staining assay measuring epitope specific tumor necrosis factor (ligand) superfamily member 11 production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A flow cytometry assay that detects tumor necrosis factor (ligand) superfamily member 11 production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>TNFSF11/RANKL release|ICS</obo:OBI_9991118>
<rdfs:label>intracellular cytokine staining assay measuring epitope specific tumor necrosis factor (ligand) superfamily member 11 production by T cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001553 -->
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<obo:IAO_0000115 xml:lang="en">A T cell epitope specific cytokine production assay that detects vascular endothelial growth factor production by T cells.</obo:IAO_0000115>
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<obo:IAO_0000115 xml:lang="en">A measurement of an IC50 value under specific assay conditions approximates KD, namely the binding reaction is at an equilibrium, there is a single population of sites on the receptor that competitor and ligand are binding to, and the concentration of the receptor must be much less than the KD for the competitor and the ligand. In this case, according to Cheng and Prussoff, KD = IC50 / (1 + Lstot / KDs), in which Lstot is the total concentration of the labeled competitor and KDs is the KD value of that competitor.</obo:IAO_0000115>
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<obo:IAO_0000115 xml:lang="en">An assay that measures the affinity of a ligand to MHC moleculs bound to the cell surface and that quantifies the affinity with a binding constant.</obo:IAO_0000115>
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<!-- http://purl.obolibrary.org/obo/OBI_0001575 -->
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<obo:IAO_0000115 xml:lang="en">An enzyme-linked immunosorbent assay that detects vascular endothelial growth factor production by T cells.</obo:IAO_0000115>
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<obo:IAO_0000111>material transport service</obo:IAO_0000111>
<obo:IAO_0000112>A service for chemical disposal</obo:IAO_0000112>
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<obo:IAO_0000115 xml:lang="en">A service in which a service provider facilitates the transport of some material entity to a specified destination for the service consumer.</obo:IAO_0000115>
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<obo:IAO_0000117>PERSON: Matthew Brush</obo:IAO_0000117>
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<!-- http://purl.obolibrary.org/obo/OBI_0001581 -->
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<obo:IAO_0000111>equilibrium dissociation constant (KD) approximated by EC50</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A measurement of an EC50 value under specific assay conditions approximates KD, namely the binding reaction is at an equilibrium, and the concentration of the receptor must be much less than the KD for the ligand.</obo:IAO_0000115>
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<rdfs:label>equilibrium dissociation constant (KD) approximated by EC50</rdfs:label>
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<obo:IAO_0000111>half life of binding datum</obo:IAO_0000111>
<obo:IAO_0000112>The 45 minute period in which one half of the complexes formed by peptide ligand bound to a HLA-A*0201molecule disassociate.</obo:IAO_0000112>
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<obo:IAO_0000111>cytometric bead array assay measuring epitope specific interleukin-7 production by T cells</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A rate measurement datum of how quickly bound complexes disassociate</obo:IAO_0000115>
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<obo:IAO_0000117>IEDB</obo:IAO_0000117>
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<obo:OBI_9991118>qualitative binding|purified MHC/direct/radioactivity</obo:OBI_9991118>
<rdfs:label>radioactivity detection assay measuring direct binding of a purified-MHC:ligand complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001609 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001609">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000916"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0032637"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
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</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000916"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001218"/>
<obo:IAO_0000111>intracellular cytokine staining assay measuring epitope specific interleukin-8 production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A flow cytometry assay that detects interleukin-8 production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>IL-8 release|ICS</obo:OBI_9991118>
<rdfs:label>intracellular cytokine staining assay measuring epitope specific interleukin-8 production by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001610 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001610">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003115"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0032627"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001363"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003115"/>
<obo:IAO_0000111>cytometric bead array assay measuring epitope specific intracellular cytokine staining (ICS) IL-23 production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometric bead array assay that detects interleukin-23 production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>IL-23 release|cytometric bead array</obo:OBI_9991118>
<rdfs:label>cytometric bead array assay measuring epitope specific intracellular cytokine staining (ICS) IL-23 production by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001611 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001611">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete purified MHC direct binding assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">direct binding assay measuring MHC ligand binding using MHC derived from a purified MHC molecule preparation</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB (QTT)</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<obo:OBI_9991118>purified MHC direct binding</obo:OBI_9991118>
<rdfs:label>obsolete purified MHC direct binding assay</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001612 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001612">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0010573"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0010573"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001193"/>
<obo:IAO_0000111>epitope specific vascular endothelial growth factor production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A process of vascular endothelial growth factor production by T cells resulting from the recognition of a T cell epitope.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB (QTT)</obo:IAO_0000119>
<obo:IAO_0000232>Date: 2011-11-10; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mappings: assay_mappings.owl</obo:IAO_0000232>
<rdfs:label>epitope specific vascular endothelial growth factor production by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001613 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001613">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001499"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001955"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001485"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0042611"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0003144"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001503"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000039"/>
<owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/UO_0000065"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001499"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001992"/>
<obo:IAO_0000111>fluorescence detection assay measuring half maximal inhibitory concentration [IC50] to determine competitive binding of a purified-MHC:ligand complex</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A fluorescence detection assay that measures half maximal inhibitory concentration (IC50) to detect the loss of binding of a known reference ligand to purified-MHC due to competition by the ligand under investigation.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>half maximal inhibitory concentration (IC50)|purified MHC/competitive/fluorescence|nM</obo:OBI_9991118>
<rdfs:label>fluorescence detection assay measuring half maximal inhibitory concentration [IC50] to determine competitive binding of a purified-MHC:ligand complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001614 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001614">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000577"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000219"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000973"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">GenBank ID</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A CRID symbol uniquely indentifies the submitted GeneBank sequence record.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<obo:OBI_0001886>GenBank Record ID</obo:OBI_0001886>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">GenBank ID</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001615 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001615">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001898"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000066"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">investigation description</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A textual entity that describes an investigation.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<obo:OBI_0001847>study description</obo:OBI_0001847>
<obo:OBI_0001886 xml:lang="en">project description</obo:OBI_0001886>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">investigation description</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001616 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001616">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000577"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000219"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100051"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">specimen identifier</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A CRID symbol denotes a specimen and used to distinguish one specimen from another in an investigation.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">specimen ID</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<obo:OBI_0001886>Specimen ID</obo:OBI_0001886>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">specimen identifier</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001617 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001617">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000577"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000219"/>
<owl:qualifiedCardinality rdf:datatype="http://www.w3.org/2001/XMLSchema#nonNegativeInteger">1</owl:qualifiedCardinality>
<owl:onClass rdf:resource="http://purl.obolibrary.org/obo/IAO_0000311"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">PubMed ID</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A CRID symbol that is sufficient to look up a citation from the PubMed, a literature database of life sciences and biomedical information.</obo:IAO_0000115>
<obo:IAO_0000116>Edits was made on Aug 24, 2016 based on OBI dev call, details see tracker: https://sourceforge.net/p/obi/obi-terms/819/</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">PMID</obo:IAO_0000118>
<obo:IAO_0000118 xml:lang="en">PubMed Identifier</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">Website: http://en.wikipedia.org/wiki/Wikipedia:PMID</obo:IAO_0000119>
<obo:OBI_0001886>Publication Citation</obo:OBI_0001886>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">PubMed ID</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001618 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001618">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000679"/>
<obo:IAO_0000111 xml:lang="en">average depth of sequence coverage</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An average value of the depth of sequence coverage based both on external (e.g. Cot-based size estimates) and internal (average coverage in the assembly) measures of genome size.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<obo:OBI_0001886>Depth of Coverage - Average</obo:OBI_0001886>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">average depth of sequence coverage</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001619 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001619">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000416"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002223"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">specimen collection time measurement datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A time measurement datum that is the measure of the time when the specimens are collected.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">collection date</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<obo:OBI_0001886>Specimen Collection Date</obo:OBI_0001886>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">specimen collection time measurement datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001620 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001620">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
<obo:IAO_0000111 xml:lang="en">latitude coordinate measurement datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A measurement datum that is the measure of the latitude coordinate of a site.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">latitude</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<obo:OBI_0001886>Specimen Collection Location - Latitude</obo:OBI_0001886>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">latitude coordinate measurement datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001621 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001621">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
<obo:IAO_0000111 xml:lang="en">longitude coordinate measurement datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A measurement datum that is the measure of the longitude coordinate of a site.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">longitude</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<obo:OBI_0001886>Specimen Collection Location - Longitude</obo:OBI_0001886>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">longitude coordinate measurement datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001622 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001622">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001898"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000219"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000066"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">investigation title</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A textual entity that denotes an investigation.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person:Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<obo:OBI_0001847>study title</obo:OBI_0001847>
<obo:OBI_0001886 xml:lang="en">project title</obo:OBI_0001886>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">investigation title</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001623 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001623">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000015"/>
<obo:IAO_0000111 xml:lang="en">organism identification objective</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A biological feature identification objective to identify the organism species in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">Penn Group</obo:IAO_0000119>
<rdfs:label xml:lang="en">organism species detection objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001624 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001624">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003498"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001623"/>
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</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003498"/>
<obo:IAO_0000111>organism species detection assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An organism detection assay that identifies the organism species in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000118>organism identification assay</obo:IAO_0000118>
<obo:IAO_0000119>NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<rdfs:label>organism species detection assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001625 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001625">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000064"/>
<obo:IAO_0000111 xml:lang="en">sequence annotation algorithm</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An algorithm used to identify sequence features (e.g. protein coding regions) in the assembled contig sequence. This may also include a description of any manual curation that may have generated or validated the annotation.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<obo:OBI_0001886>Annotation Algorithm</obo:OBI_0001886>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">sequence annotation algorithm</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001626 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001626">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000245"/>
<obo:IAO_0000111 xml:lang="en">Bioinformatics Resource Center</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An organization that is one of the Internet-based research centers established and funded by NIAID (the National Institute of Allergy and Infectious Diseases). The Bioinformatics Resource Centers (BRCs) were formed in response to the threats posed by emerging and re-emerging pathogens, particularly CDC Category A, B, and C pathogens, and their potential use in bioterrorism. The intention of NIAID in funding these bioinformatics centers is to assist researchers involved in the experimental characterization of such pathogens and the formation of drugs, vaccines, or diagnostic tools to combat them.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">BRC</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">Website: http://en.wikipedia.org/wiki/Bioinformatics_Resource_Centers</obo:IAO_0000119>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">Bioinformatics Resource Center</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001627 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001627">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000300"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000219"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GAZ_00000448"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">country name</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A textual entity that denotes a geographic location that is a site or part of a site that is identified as a country in the political geography.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">Website: http://en.wikipedia.org/wiki/Country</obo:IAO_0000119>
<obo:OBI_0001886>Specimen Collection Location - Country</obo:OBI_0001886>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">country name</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001628 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001628">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000577"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000219"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000066"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">investigation identifier</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A CRID symbol used to identify an investigation.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Chris Stoeckert, Jie Zhneg</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<obo:OBI_0001886 xml:lang="en">project ID</obo:OBI_0001886>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">investigation identifier</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001629 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001629">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000577"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000219"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001636"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">grant identifier</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A CRID symbol used to identify a grant.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<obo:OBI_0001886 xml:lang="en">grant ID</obo:OBI_0001886>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">grant identifier</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001630 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001630">
<owl:equivalentClass>
<owl:Class>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
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<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000038"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000038"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000086"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000601"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000601"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<obo:IAO_0000111>analytical chromatography</obo:IAO_0000111>
<obo:IAO_0000112>Detection of the presence of blood group A specific antibodies by passing a serum sample through an affinity column containing blood group A carbohydrate, and quantifying the protein content eluted from the column.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that uses a biomaterial's preferential affinity for either the mobile phase or the stationary phase to separate it from other materials and thereby detect its presence in an input material.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>analytical chromatography</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001631 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001631">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000185"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000990"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000990"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002119"/>
<obo:IAO_0000111>electron microscopy imaging assay</obo:IAO_0000111>
<obo:IAO_0000112>Using gold labeled antibodies to stain a mouse brain slice and use electron microscopy to generate an image that shows the location of the antibodies within the tissue structure.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An imaging assay in which an electrons are used to probe the density, shape and composition of an input material which are detected in an electron microscope and utilized to produce an image of the material.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>electron microscopy imaging assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001632 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001632">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600017"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002743"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0042571"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0042571"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>immuno staining assay</obo:IAO_0000111>
<obo:IAO_0000112>Detection of the presence of VCAM molecules on the surface of cells in a histology slide using an enzyme-linked antibody followed by enzyme activation to release a dye.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A assay detecting a molecular label assay in which the label is attached to an antibody so that substances are marked based on the antibody's binding specificity.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>immuno staining assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001633 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001633">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001505"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<obo:IAO_0000111>purified material</obo:IAO_0000111>
<obo:IAO_0000112>A mixture of peptide molecules that has been run through an HPLC column to remove 65</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A material entity that is generated by a purification process in which an input material is separated to obtain a fraction with a higher concentration of a desired component</obo:IAO_0000115>
<obo:IAO_0000117>GROUP: OBI call</obo:IAO_0000117>
<obo:IAO_0000119>OBI conference call</obo:IAO_0000119>
<rdfs:label>purified material</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001634 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001634">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001146"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000930"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000930"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001146"/>
<obo:IAO_0000111>calorimetric binding assay</obo:IAO_0000111>
<obo:IAO_0000112>A solution of a proteins is titrated into a solution containing a specific antibody. The heat released upon their interaction (delta H) is monitored over time where each peak represents a heat change associated with the injection of a small volume of sample into the reaction cell. As successive amounts of the ligand are titrated into the cell, the quantity of heat absorbed or released is in direct proportion to the amount of binding. As the system reaches saturation, the heat signal diminishes until only heats of dilution are observed. A binding curve is then obtained from a plot of the heats from each injection against the ratio of protein and antibody in the cell ._</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A binding assay in which the heat generated or absorbed during a binding event is measured, which allows determination of binding constants, reaction stoichiometry, enthalpy and entropy.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>calorimetric binding assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001635 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001635">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001979"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0042571"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0042571"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001501"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003368"/>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001588"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>antibody binding detection by fluorescence quenching</obo:IAO_0000111>
<obo:IAO_0000112>The binding affinity of Fab 4-4-20 for the fluorescein molecule was determined using the fluorescence quenching assay, by placing the Fab and the fluorescein together in a well and measuring the fluorescence after each addition of increasing concentrations of the Fab (PMID: 8637844).</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A binding assay in which affinity is measured by detecting a change in fluorescence (usually quenching) that occurs upon binding of the antibody to the ligand. The fluorescent signal that is affected by binding is either from an exogenous fluorophore attached to the ligand, or is the intrisic fluorescence of aromatic (tryptophan) residues on the binding site of the antibody (no conjugated fluorophore necessary) or, less commonly, on the ligand binding region (epitope).</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>antibody binding detection by fluorescence quenching</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001636 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001636">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000104"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">grant</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A plan specification of organization A to give money to organization B so that B conducts investigations. Organization A has funder role and Organization B has research organization role.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">Discussed on Feb 13, 2012 dev call. Details see the tracker:
https://sourceforge.net/tracker/?func=detail&aid=3483338&group_id=177891&atid=886178</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Group: OBI</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI</obo:IAO_0000119>
<obo:IAO_0000232>AR: Grant isn't a plan specification, it has a part which is a plan specification. See tracker: https://sourceforge.net/tracker/?func=detail&aid=3483338&group_id=177891&atid=886178</obo:IAO_0000232>
<rdfs:label xml:lang="en">grant</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001638 -->
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<!-- http://purl.obolibrary.org/obo/OBI_0001668 -->
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<obo:IAO_0000115 xml:lang="en">A binding assay that screens membrane soluble proteins by fusion of two integral membrane proteins (bait and prey) to two different ubiquitin moieties. One moiety is also fused to a transcription factor (TF) that can be cleaved off by ubiquitin specific proteases. Upon bait and prey interaction, Nub and Cub-moieties assemble, reconstituting the split-ubiquitin. The reconstituted split-ubiquitin molecule is recognized by ubiquitin specific proteases, which cleave off the reporter protein, allowing it to induce the transcription of reporter genes.</obo:IAO_0000115>
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<obo:IAO_0000115 xml:lang="en">An assay that measures protein-protein interactions by separating target proteins on an SDS-PAGE gel, transfering them to a solid substrate, hybridizing with a protein probe and visualizing bound proteins using a probe-directed antibody. This is a adaptation on the western blot assay.</obo:IAO_0000115>
<obo:IAO_0000117>Marcus Chibucos</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>PMID:18079728</obo:IAO_0000119>
<rdfs:label>far-western blot assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001670 -->
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<obo:IAO_0000111>RNA protection assay</obo:IAO_0000111>
<obo:IAO_0000112>Absolute concentrations of mRNA for type I and type VI collagen in the canine meniscus in normal and ACL-deficient knee joints obtained by RNase protection assay. PMID:11518275</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An assay that determines the presence and estimates abundance of transcript species by first creating an homo or heteroduplex by adding a specific, complementary sequence to the sequence of interest and then exposing the mixture of ribonuclease, which will degrade only single stranded molecules. A detection step will reveal if the sample contained a sequence of interest.</obo:IAO_0000115>
<obo:IAO_0000117>Marcus Chibucos</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>RNAse protection assay</obo:IAO_0000118>
<obo:IAO_0000118>RPA</obo:IAO_0000118>
<obo:IAO_0000119>PMID:16491611</obo:IAO_0000119>
<rdfs:label>RNA protection assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001671 -->
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<obo:IAO_0000111>electrophoretic mobility shift assay</obo:IAO_0000111>
<obo:IAO_0000112>Electrophoretic mobility shift assay reveals a novel recognition sequence for Setaria italica NAC protein. PMID:21918373</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures information about Protein-DNA or Protein-RNA interactions using gel electrophoresis and relying on the fact the molecular interactions will cause the heterodimer to be retarded on the gel when compared to controls corresponding to protein extract alone and protein extract + neutral nucleic acid.</obo:IAO_0000115>
<obo:IAO_0000117>Marcus Chibucos</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>EMSA</obo:IAO_0000118>
<obo:IAO_0000118>band shift assay</obo:IAO_0000118>
<obo:IAO_0000118>gel mobility shift assay</obo:IAO_0000118>
<obo:IAO_0000118>gel retardation assay</obo:IAO_0000118>
<obo:IAO_0000118>gel shift assay</obo:IAO_0000118>
<obo:IAO_0000119>PMID:6269071</obo:IAO_0000119>
<rdfs:label>electrophoretic mobility shift assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001672 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001672">
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0008150"/>
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<obo:IAO_0000111>gene knock-down assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An assay which transiently disrupts gene transcripts by expressing antisense RNA constructs or delivering RNA interfering molecules in cells.</obo:IAO_0000115>
<obo:IAO_0000117>Marcus Chibucos</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>PMID:17430206</obo:IAO_0000119>
<rdfs:label>gene knock-down assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001673 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001673">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000424"/>
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<obo:IAO_0000111>nano-cap analysis of gene expression assay</obo:IAO_0000111>
<obo:IAO_0000112>Linking promoters to functional transcripts in small samples with nanoCAGE and CAGEscan._PMID:20543846</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A transcription profiling assay that is performed using a very low amount (nanogram scale) of mRNA samples using Cap analysis gene expression (CAGE).</obo:IAO_0000115>
<obo:IAO_0000117>Marcus Chibucos</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>nano-CAGE</obo:IAO_0000118>
<obo:IAO_0000119>PMID:20543846</obo:IAO_0000119>
<rdfs:label>nano-cap analysis of gene expression assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001674 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002692"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600047"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
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</owl:someValuesFrom>
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<rdfs:subClassOf>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001331"/>
</owl:Restriction>
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<obo:IAO_0000111>cap analysis of gene expression assay</obo:IAO_0000111>
<obo:IAO_0000112>5' end-centered expression profiling using cap-analysis gene expression and next-generation sequencing. PMID:22362160</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A transcription profiling assay which measures RNA transcript abundances in biological samples by extracting 5' ends of capped transcripts, RTPCR and sequence those. Copy numbers of CAGE tags provide a way of quantification and provide a measure of expression of the transcriptome</obo:IAO_0000115>
<obo:IAO_0000117>Marcus Chibucos</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>CAGE</obo:IAO_0000118>
<obo:IAO_0000119>PMID:14663149</obo:IAO_0000119>
<rdfs:label>cap analysis of gene expression assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001675 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001773"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110162"/>
<obo:IAO_0000111>ELISA measuring epitope specific interleukin-17A production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An enzyme-linked immunosorbent assay that detects interleukin-17A production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>IL-17A release|ELISA</obo:OBI_9991118>
<rdfs:label>ELISA measuring epitope specific interleukin-17A production by T cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001676 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001587"/>
<obo:IAO_0000111>detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-7 production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A detection of specific nucleic acid polymers with complementary probes that detects interleukin-7 production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>IL-7 release|RNA/DNA detection</obo:OBI_9991118>
<rdfs:label>detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-7 production by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001677 -->
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0036262"/>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0036262"/>
<obo:IAO_0000111>epitope specific granulysin production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A process of granulysin production by T cells resulting from the recognition of a T cell epitope.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB (QTT)</obo:IAO_0000119>
<obo:IAO_0000232>Date: 2011-6-24; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mappings: MMExpressionsTcell.txt</obo:IAO_0000232>
<rdfs:label>epitope specific granulysin production by T cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001678 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0035746"/>
<obo:IAO_0000111>epitope specific granzyme A production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A process of granzyme A production by T cells resulting from the recognition of a T cell epitope.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB (QTT)</obo:IAO_0000119>
<obo:IAO_0000232>Date: 2011-6-24; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mappings: MMExpressionsTcell.txt</obo:IAO_0000232>
<rdfs:label>epitope specific granzyme A production by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001679 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001679">
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<obo:IAO_0000111>yeast 2-hybrid assay</obo:IAO_0000111>
<obo:IAO_0000112>Strong FANCA/FANCG but weak FANCA/FANCC interaction in the yeast 2-hybrid system. PMID:10627486</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An assay that detects protein protein interactions and protein DNA interactions by testing for physical interactions (such as binding) between two proteins or a single protein and a DNA molecule, respectively. The premise behind the test is the activation of downstream reporter gene(s) by the binding of a transcription factor onto an upstream activating sequence (UAS). For two-hybrid screening, the transcription factor is split into two separate fragments, called the binding domain (BD) and activating domain (AD). The BD is the domain responsible for binding to the UAS and the AD is the domain responsible for the activation of transcription. The Y2H is thus a protein-fragment complementation assay.</obo:IAO_0000115>
<obo:IAO_0000117>Marcus Chibucos</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>Y2H</obo:IAO_0000118>
<obo:IAO_0000119>url:https://en.wikipedia.org/wiki/Two-hybrid_screening</obo:IAO_0000119>
<rdfs:label>yeast 2-hybrid assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001680 -->
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<obo:IAO_0000111>Sos-recruitment assay</obo:IAO_0000111>
<obo:IAO_0000112>The Sos-recruitment system as a tool to analyze cellular localization of plant proteins: membrane localization of Arabidopsis thaliana PEPINO/PASTICCINO2. PMID:20300944</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A binding assay that detects interacting proteins for a targeted domain where mammalian guanyl nucleotide exchange factor (GEF) Sos is recruited to the Saccharomyces cerevisiae plasma membrane harboring a temperature-sensitive Ras GEF, Cdc25-2, allowing growth at the nonpermissive temperature using the Sos recruitment system, a kind of yeast 2 hybrid system.</obo:IAO_0000115>
<obo:IAO_0000117>Marcus Chibucos</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>SRS</obo:IAO_0000118>
<obo:IAO_0000119>PMID:9154808</obo:IAO_0000119>
<rdfs:label>Sos-recruitment assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001681 -->
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</owl:someValuesFrom>
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<obo:IAO_0000111>yeast one-hybrid assay</obo:IAO_0000111>
<obo:IAO_0000112>Yeast one-hybrid assays for gene-centered human gene regulatory network mapping. PMID:22037702</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An assay that determines protein DNA interactions using a single fusion protein in which the activating domain is linked directly to the binding domain.</obo:IAO_0000115>
<obo:IAO_0000117>Marcus Chibucos</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>Y1H</obo:IAO_0000118>
<obo:IAO_0000119>PMID:22218861</obo:IAO_0000119>
<rdfs:label>yeast one-hybrid assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001682 -->
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<obo:IAO_0000111>bacterial one-hybrid assay</obo:IAO_0000111>
<obo:IAO_0000112>A systematic characterization of factors that regulate Drosophila segmentation via a bacterial one-hybrid system. PMID:18332042</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An assay that identifies the sequence-specific target site of a DNA-binding domain. In this system, a given transcription factor (TF) is expressed as a fusion to a subunit of RNA polymerase. In parallel, a library of randomized oligonucleotides representing potential TF target sequences, is cloned into a separate vector containing the selectable genes HIS3 and URA3. If the DNA-binding domain (bait) binds a potential DNA target site (prey) in vivo, it will recruit RNA polymerase to the promoter and activate transcription of the reporter genes in that clone. The two reporter genes, HIS3 and URA3, allow for positive and negative selections, respectively. At the end of the process, positive clones are sequenced and examined with motif-finding tools in order to resolve the favoured DNA target sequence</obo:IAO_0000115>
<obo:IAO_0000117>Marcus Chibucos</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>B1H</obo:IAO_0000118>
<obo:IAO_0000119>url:http://en.wikipedia.org/wiki/Bacterial_one-hybrid_system</obo:IAO_0000119>
<rdfs:label>bacterial one-hybrid assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001683 -->
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</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>chromosome organization assay by fluorescence in-situ hybridization</obo:IAO_0000111>
<obo:IAO_0000112>Duplication of intrachromosomal insertion segments 4q32__�q35 confirmed by comparative genomic hybridization and fluorescent in situ hybridization. PMID:22384449</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An in-situ hybridization assay that uses fluorescence to detect chromosomal integrity</obo:IAO_0000115>
<obo:IAO_0000117>Marcus Chibucos</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/788|</obo:IAO_0000233>
<rdfs:label>chromosome organization assay by fluorescence in-situ hybridization</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001684 -->
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<obo:IAO_0000111>methylation-specific polymerase chain reaction assay</obo:IAO_0000111>
<obo:IAO_0000112>Methylation status of breast cancer resistance protein detected by methylation-specific polymerase chain reaction analysis is correlated inversely with its expression in drug-resistant lung cancer cells. PMID:18219662</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An assay that uses initial modification of DNA by sodium bisulfite, converting all unmethylated, but not methylated, cytosines to uracil, and subsequent amplification with primers specific for methylated versus unmethylated DNA.</obo:IAO_0000115>
<obo:IAO_0000117>Marcus Chibucos</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>MSP</obo:IAO_0000118>
<obo:IAO_0000119>PMID:8790415</obo:IAO_0000119>
<rdfs:label>methylation-specific polymerase chain reaction assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001685 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001685">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000634"/>
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</owl:someValuesFrom>
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<rdfs:subClassOf>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000834"/>
</owl:Restriction>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
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</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>amplification of intermethylated sites assay</obo:IAO_0000111>
<obo:IAO_0000112>Analysis of DNA methylation by amplification of intermethylated sites (AIMS). PMID:18987810</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An assay that estimates genome-wide DNA methylation and measures methylation of DNA sequences. AIMS is based on the differential enzymatic digestion of genomic DNA with methylation-sensitive and methylation-insensitive isoschizomers followed by restrained PCR amplification of methylated sequences.</obo:IAO_0000115>
<obo:IAO_0000117>Marcus Chibucos</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>AIMS assay</obo:IAO_0000118>
<obo:IAO_0000118>intermethylated site amplification</obo:IAO_0000118>
<obo:IAO_0000119>PMID:18987810</obo:IAO_0000119>
<rdfs:label>amplification of intermethylated sites assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001686 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001686">
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0302903"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001143"/>
</owl:Restriction>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0033036"/>
</owl:Restriction>
</owl:someValuesFrom>
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</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>in-situ hybridization assay</obo:IAO_0000111>
<obo:IAO_0000112>Use of in situ hybridization to examine gene expression in the embryonic, neonatal, and adult urogenital system. PMID:22639265</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An assay that localizes a specific DNA or RNA sequence within a portion or section of tissue using artificially induced nucleic hybridization.</obo:IAO_0000115>
<obo:IAO_0000117>Marcus Chibucos</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>ISH</obo:IAO_0000118>
<obo:IAO_0000118>in situ hybridization</obo:IAO_0000118>
<obo:IAO_0000119>PMID:9021518</obo:IAO_0000119>
<rdfs:label>in-situ hybridization assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001687 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001687">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">contact representative role</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A role inhering in a person who represents an institution, organization, or service provider and realized when communication is directed at them about the entity they represent.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">Discussed on May 7, 2012 dev call
propose:contact role, type of organization role, and create shortcut relation between 'organization role' and 'organization' ?
Whether it works for communicating author in manuscript or not?
Tracker:
https://sourceforge.net/tracker/?func=detail&aid=3512891&group_id=177891&atid=886178</obo:IAO_0000116>
<obo:IAO_0000117>Person: Chris Stoeckert</obo:IAO_0000117>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">contact representative role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001689 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001689">
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23528"/>
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<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>in vivo activity|biological activity</obo:OBI_9991118>
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<obo:IAO_0000111>antibody cross-blocking assay</obo:IAO_0000111>
<obo:IAO_0000112>Testing two antibodies that bind the HBV core protein for the ability of one antibody pre-incubated with the protein in solution to inhibit binding to the other antibody which is plate-bound in an ELISA format.</obo:IAO_0000112>
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<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000118>antibody inhibition of antibody binding</obo:IAO_0000118>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
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<obo:IAO_0000111>immunoprecipitation assay</obo:IAO_0000111>
<obo:IAO_0000112>Determining if a cell is producing a protein using a protein specific antibody to immunoprecipitate the cell lysate. Determining if the serum of a patient contains antibodies against HBV core protein by immunoprecipitating purified HBV core protein with the patients serum.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay in which an input material is mixed with antibodies and bound antigen:antibody complexes are separated out using immunoprecipitation. Either the antibody has known specificy, and the antigen mixture is tested for the presence of a specific antigen, or the antigen solution is well defined and the antibody solution is tested for the presence of antigen specific antibodies.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
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<obo:IAO_0000111>antigen inhibition assay measuring binding of a B cell epitope:antibody complex</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A B cell epitope qualitative binding to antibody assay that measures the ability of an antigen to inhibit antibody binding to a known ligand.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>qualitative binding|inhibition by antigen</obo:OBI_9991118>
<rdfs:label>antigen inhibition assay measuring binding of a B cell epitope:antibody complex</rdfs:label>
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<obo:IAO_0000111>immunoglobulin binding to epitope</obo:IAO_0000111>
<obo:IAO_0000112>Binding of the LA5 antibody to a discontinuous set of amino acid residues on the surface of the D8 protein of Vaccinia virus.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
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<obo:IAO_0000117>PERSON: Bjoern Peters, Randi Vita</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
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<obo:IAO_0000115 xml:lang="en">An assay that detects the binding of an antigen with an antibody, and produces a qualitative measurement of the binding as an output.</obo:IAO_0000115>
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<obo:IAO_0000111>assay measuring epitope specific activation of additional immune response in vitro</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A B cell epitope dependent biological activity determination assay that detects secondary in vitro activity.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
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<!-- http://purl.obolibrary.org/obo/OBI_0001705 -->
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<obo:IAO_0000115 xml:lang="en">A B cell epitope dependent biological activity determination assay that detects inhibition of the antibody's activity by the antigen.</obo:IAO_0000115>
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<!-- http://purl.obolibrary.org/obo/OBI_0001706 -->
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<obo:IAO_0000111>assay measuring biological activity resulting from B cell epitope:antibody binding</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A B cell epitope assay that measures the immune response process resulting from the binding of an antibody receptor to epitope or recognition of the epitope.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
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<obo:IAO_0000115 xml:lang="en">The release of histamine by cells stimulated through their Fc receptors which are loaded with immunoglobulins.</obo:IAO_0000115>
<obo:IAO_0000116>4/26/12, BP: We want to import this from GO, which currently only has IgE mediated histamine release. We have requested the term, but need to use this as a placeholder in the meanwhile.</obo:IAO_0000116>
<obo:IAO_0000117>PERSON: Bjoern Peters, Randi Vita</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>immunoglobulin mediated histamine release</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001708 -->
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<obo:IAO_0000115 xml:lang="en">A B cell epitope binding constant determination assay that measures the dissociation constant KD.</obo:IAO_0000115>
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<obo:IAO_0000119>IEDB</obo:IAO_0000119>
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<obo:IAO_0000115 xml:lang="en">opsonization resulting from antibody binding to epitope</obo:IAO_0000115>
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<obo:IAO_0000115 xml:lang="en">immunoglobulin-mediated neutralization resulting from antibody binding to epitope</obo:IAO_0000115>
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<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
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<obo:IAO_0000119>Penn Group</obo:IAO_0000119>
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<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
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<obo:IAO_0000119>Jie Zheng</obo:IAO_0000119>
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<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000117>Venkat Malladi</obo:IAO_0000117>
<obo:IAO_0000118>CLIP-seq</obo:IAO_0000118>
<obo:IAO_0000118>CLIP-seq assay</obo:IAO_0000118>
<obo:IAO_0000118>HITS-CLIP</obo:IAO_0000118>
<obo:IAO_0000119>PMID:18978773</obo:IAO_0000119>
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<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
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<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000117>Venkat Malladi</obo:IAO_0000117>
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<obo:IAO_0000118>MRE-seq assay</obo:IAO_0000118>
<obo:IAO_0000119>PMID:20613842</obo:IAO_0000119>
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<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000117>Venkat Malladi</obo:IAO_0000117>
<obo:IAO_0000118>RRBS</obo:IAO_0000118>
<obo:IAO_0000118>RRBS assay</obo:IAO_0000118>
<obo:IAO_0000118>reduced representation bisulfite-seq</obo:IAO_0000118>
<obo:IAO_0000119>PMC:1258174</obo:IAO_0000119>
<rdfs:label>reduced representation bisulfite sequencing assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001863 -->
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<obo:IAO_0000111>shotgun bisulfite-seq assay</obo:IAO_0000111>
<obo:IAO_0000112>Cokus et al. Shotgun bisulfite sequencing of the Arabidopsis genome reveals DNA methylation patterning. Nature. 2008 Mar 13;452(7184):215-9. [PMID:18278030].</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A bisulfite sequencing assay that identifies methylated cytosines across the genome using high throughput sequencing.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000117>Venkat Malladi</obo:IAO_0000117>
<obo:IAO_0000118>Shotgun bisulfite sequencing</obo:IAO_0000118>
<obo:IAO_0000118>WGBS</obo:IAO_0000118>
<obo:IAO_0000118>WGSBS</obo:IAO_0000118>
<obo:IAO_0000118>whole genome bisulfite sequencing</obo:IAO_0000118>
<obo:IAO_0000118>whole-genome shotgun bisulfite sequencing</obo:IAO_0000118>
<obo:IAO_0000119>PMID:18278030</obo:IAO_0000119>
<rdfs:label>shotgun bisulfite-seq assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001864 -->
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<obo:IAO_0000111>RNA Annotation and Mapping of Promoters for the Analysis of Gene Expression assay</obo:IAO_0000111>
<obo:IAO_0000112>Batut et al. High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression. Genome Research. 2013 Jan;23(1):169-80. [PMID:22936248]</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An transcription profiling assay that identifies transcription start sites (TSS), the quantification of their expression and the characterization of their transcripts using high throughput sequencing.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000117>Venkat Malladi</obo:IAO_0000117>
<obo:IAO_0000118>RAMPAGE</obo:IAO_0000118>
<obo:IAO_0000119>PMID:22936248</obo:IAO_0000119>
<rdfs:label>RNA Annotation and Mapping of Promoters for the Analysis of Gene Expression assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001865 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001865">
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<obo:IAO_0000111>assay array</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device made to be used in an analyte assay for immobilization of substances that bind the analyte at regular spatial positions on a surface.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng, Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000119>Penn Group</obo:IAO_0000119>
<rdfs:label>assay array</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001866 -->
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<obo:IAO_0000111>secondary cultured cell</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cultured cell that has been passaged or derives from a cell that has been passaged in culture.</obo:IAO_0000115>
<obo:IAO_0000116>The term 'secondary cell culture' is generally used in biological texts/protocols to refer to any culture following an initial passage. We include it here because there are often a number of passages between a primary culture and the establishment of a stable, homogenous cell line. Such cultures are considered to be 'secondary cultures' but not 'cell lines' during this intermediate passaging/selection period between their derivation from a 'primary cell culture' and derivation into a 'cell line', which is a more specific type of secondary culture.</obo:IAO_0000116>
<obo:IAO_0000117>Person: Matthew Brush</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Matthew Brush</obo:IAO_0000119>
<rdfs:comment>A secondary cultured cell has been passaged in culture or is a descendant of such a cell that is derived through propagation in culture.</rdfs:comment>
<rdfs:label>secondary cultured cell</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001867 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001867">
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<obo:IAO_0000111>establishing cell line</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a process whereby a new type of cell line is created, either through passaging of a primary cell culture to relative genetic stability and compositional homogeneity, or through some experimental modification of an existing cell line to produce a new line with novel characteristics (e.g. immortalization or some other stable genetic modification, or selection of some defined subset).</obo:IAO_0000115>
<obo:IAO_0000116>2013-4-20 MHB: For cases of initial establilshment of a line from a primary culture, successive passaging and/or selection processes can confer increasing degrees of genetic stability and compositional homogeneity as compared to the input primary culture. Historically, many texts consider the first passage as the clearest point to define the beginning of a line. However, in practice it is more often that case that more than one passage, and possibly additional selective techniques, may be required before a culture is deemed to have sufficient stability and homogeneity to be considered cell line. This is the view taken in OBI. Regardless, what is important is that some intentional, experimental step has been taken to establish a more homogenous and stable culture that can be characterized and progatated over time.</obo:IAO_0000116>
<obo:IAO_0000117>Person: Matthew Brush</obo:IAO_0000117>
<obo:IAO_0000119>PERSON:Matthew Brush</obo:IAO_0000119>
<rdfs:label>establishing cell line</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001868 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001868">
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<obo:IAO_0000111>genetic material</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000115 xml:lang="en">A nucleic acid macromolecule that is part of a cell or virion and is inherited from an immediate ancestor, or incorporated in a manner that it has the disposition to be replicated and inherited by descendants.</obo:IAO_0000115>
<obo:IAO_0000116>MHB 3-22-13: Discussions are ongoing about the label of this class, given consideration of a second class that covers nucleic acid parts of cells or virions that participate in gene expression processes as a template for expression or a direct effector of expression of some other genetic element (e.g. an siRNA), but are not necessarily heritable by progeny or inherited from ancestors. So things like transiently transfected plasmids and siRNAs would qualify as instances of this second class, but not of 'genetic material' as defined here.
Also, OBI needs to import a class representing virions for an axiom on genetic material (part_of some (cell or virion).</obo:IAO_0000116>
<obo:IAO_0000118>genomic material</obo:IAO_0000118>
<obo:IAO_0000118>hereditary genetic material</obo:IAO_0000118>
<obo:IAO_0000119>OBI developer calls, March 4 2013 and March 11 2013</obo:IAO_0000119>
<rdfs:comment>Naturally occurring or experimentally incorporated nucleic acids that meet these criteria can qualify as genetic/genomic material.
Qualifying examples include: (1) inherited chromosomal DNA in germ cells, stem cells, fully differentiated cells, or cell line cells, or the DNA/RNA content of a virion; (2) natural replicons exchanged through horizontal gene transfer mechanisms such as bacterial conjugation, which are capable of replication and inheritance by progeny; (3) a chromosomally integrated gene targeting DNA construct transfected into a cell; or (4) a stable extra-chromosomal replicon delivered into cells, such as a plasmid in bacterial host with ori allowing indefinite propagation.
Non-qualifying examples include a transiently transfected plasmid or siRNA oligo (as these are not able to be replicated and inherited by progeny cells).</rdfs:comment>
<rdfs:label>genetic material</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001869 -->
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<obo:IAO_0000111>Illumina BeadChip</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An array that consists of 3-micron silica beads that self assemble in microwells on either of two materials: fiber optic bundles or planar silica slides.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng, Alan Ruttenberg, Venkat Malladi</obo:IAO_0000117>
<obo:IAO_0000119>http://www.illumina.com/technology/beadarray_technology.ilmn</obo:IAO_0000119>
<rdfs:label>Illumina BeadChip</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001870 -->
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<obo:IAO_0000111>Illumina methylation BeadChip</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A BeadChip made for an analyte assay that generates information about DNA methylation.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng, Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000119>Penn Group</obo:IAO_0000119>
<rdfs:label>Illumina methylation BeadChip</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001871 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001871">
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<obo:IAO_0000111>LSRFortessa X-20</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A flow cytometer analyzer manifactured by Becton ans Dickinson. Can be configured with up to 5 lasers, 488nm, 532 or 561 nm, 640 nm, 405 nm, 355 nm for measuring up to 20 parameters simultaneously.</obo:IAO_0000115>
<obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
<obo:IAO_0000119>http://www.bdbiosciences.com/instruments/lsrx20/index.jsp?WT.srch=1&gclid=CJjJ8JTR5LoCFXBo7AodZycAbg</obo:IAO_0000119>
<rdfs:label>LSRFortessa X-20</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001872 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001872">
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</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">sequence assembly process</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A data transformation that assembles two or more individual sequence reads into contiguous sequences (i.e., contigs).</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">PRS/AGB:
changed to restrictions by adding 2 possible specified outputs (N50 and genome coverage) for sequence assembly.</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Alejandra Gonzalez-Beltran</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Jie Zheng, Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">sequence assembly process</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001873 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001873">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001933"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0001937"/>
<owl:someValuesFrom rdf:resource="http://www.w3.org/2001/XMLSchema#integer"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">number of errors</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Gigascience. 2012 Dec 27;1(1):18. doi: 10.1186/2047-217X-1-18.
PMID: 23587118. see table2</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">a data item that is the number of times that a given process failed, as an integer</obo:IAO_0000115>
<obo:IAO_0000117>Alejandra Gonzalez-Beltran</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PRS, AGB</obo:IAO_0000119>
<rdfs:label xml:lang="en">number of errors</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001874 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001874">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000032"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001877"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400107"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">random access memory size</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Gigascience. 2012 Dec 27;1(1):18. doi: 10.1186/2047-217X-1-18.
PMID: 23587118.
"However, the error correction module in SOAPdenovo was designed for short Illumina reads (35-50 bp), which consumes an excessive amount of computational time and memory on longer reads, for example, over 150 GB memory running for two days using 40-fold 100 bp paired-end Illumina HiSeq 2000 reads"</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">random access memory size is a scalar measurement datum which denotes the amount of physical memory know as random access memory present of a computer or required by a computational process or data transformation</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Alejandra Gonzalez-Beltran</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PRS, AGB</obo:IAO_0000119>
<rdfs:label xml:lang="en">random access memory size</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001875 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001875">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0100060"/>
<obo:IAO_0000111>cultured immune cell population</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a cultured cell population comprised of a single type of immune system cell</obo:IAO_0000115>
<obo:IAO_0000116>MHB 3-5-13: created as a (temporary) organizational class to organize IEDB immune cultured cell population types. These were all previously labled as 'cell cultures' - and relabeld here as 'cultured cell populations' since a CLO alignment outcome was to use the term 'cell culture' to refer to cultured cells + media. Consult with BP as to whether this organizational class is useful and if so, how to define it. Also check whether the intent was to represent cell populations rather than cell cultures.</obo:IAO_0000116>
<obo:IAO_0000117>PERSON:Matthew Brush</obo:IAO_0000117>
<obo:IAO_0000118>immune cell culture sample</obo:IAO_0000118>
<obo:IAO_0000119>PERSON:Matthew Brush</obo:IAO_0000119>
<rdfs:label xml:lang="en">cultured immune cell population</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001876 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001876">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000010"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000079"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001912"/>
</owl:unionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>cell culture</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A material entity comprised of cultured cells and the media in which they are being propagated or stored.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Matthew Brush</obo:IAO_0000117>
<obo:IAO_0000119>OBI-CLO Alignment Working Group (Spring 2013)</obo:IAO_0000119>
<rdfs:comment>A cell culture includes the cells in culture, as well as the media and all additives in which the cells are being grown or in which they are stored.</rdfs:comment>
<rdfs:label>cell culture</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001877 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001877">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000178"/>
<obo:IAO_0000111 xml:lang="en">random access memory</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">Random-access memory (RAM) is a form of computer data storage. A random-access device allows stored data to be accessed directly in any random order. In contrast, other data storage media such as hard disks, CDs, DVDs and magnetic tape, as well as early primary memory types such as drum memory, read and write data only in a predetermined order, consecutively, because of mechanical design limitations. Therefore, the time to access a given data location varies significantly depending on its physical location</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Alejandra Gonzalez-Beltran</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">RAM</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">http://en.wikipedia.org/wiki/RAM
last accessed: 2013-12-02</obo:IAO_0000119>
<rdfs:label xml:lang="en">random access memory</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001878 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001878">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600036"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100061"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">establishing primary cell culture</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Effects of establishing cell cultures and cell culture conditions on the proliferative life span of human fibroblasts isolated from different tissues and donors of different ages.
Exp Cell Res. 2002 Apr 1;274(2):275-87. PMID: 11900488
When harvesting blood from a human, isolating T cells, and then limited dilution cloning of the cells, the establishing_cell_culture step comprises preparing the cells at a certain dilution and plating them in a container with growth medium.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">an establishing cell culture process whereby cells explanted directly from an organismal source or specimen, and placed in culture for maintenance or propagation as a primary cell culture</obo:IAO_0000115>
<obo:IAO_0000119 xml:lang="en">PERSON: Matthew Brush</obo:IAO_0000119>
<rdfs:comment>Cells are originally plated at a certain concentration referred to as seeding density. Upon a first passage this primary culture becomes a secondary cell culture that can be propagated to become a stable and homogneous cell line. This class covers establishment of primary cultures from any native cell - 'in vivo' cells isolated from some multicellular organism, or 'in environment' unicellular organisms isolated from some natural environment.</rdfs:comment>
<rdfs:label xml:lang="en">establishing primary cell culture</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001879 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001879">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000086"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">reagent</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A biological or chemical entity that bears a reagent role in virtue of it being intended for application in a scientific technique to participate in (or have molecular parts that participate in) a chemical reaction that facilitates the generation of data about some distinct entity, or the generation of some distinct material specified output.</obo:IAO_0000115>
<obo:IAO_0000116>2013-6-5 MHB: Clarifications regarding the distinction between reagetns and devices were made at the May 2013 Philly Workshop. Reagents are distinguished from devices that also participate in scientific techniques by the fact that reagents are chemical or biological in nature and necessarily participate in some chemical interaction or reaction during the realization of their experimental role. By contrast, devices do not participate in such chemical reactions/interactions. Note that there are cases where devices use reagent components during their operation, where the reagent-device distinction is less clear. For examples, see editor note on OBI:device.</obo:IAO_0000116>
<obo:IAO_0000117>PERSON:Matthew Brush</obo:IAO_0000117>
<obo:IAO_0000119>PERSON:Matthew Brush</obo:IAO_0000119>
<rdfs:comment>(copied from ReO)
Reagents are distinguished from devices/instruments that also serve as facilitators in scientific techniques by the fact that reagents are chemical or biological in nature and necessarily participate in or have parts that participate in some chemical interaction or reaction during their intended participation in some technique. By contrast, devices do not participate in a chemical reaction/interaction during the technique.
Reagents are distinguished from study subjects/evaluants in that study subjects and evaluants are that about which conclusions are drawn and knowledge is sought in an investigation - while reagents, by definition, are not. It should be noted, however, that reagent and study subject/evaluant roles can be borne by instances of the same type of material entity - but a given instance can only realize one of these roles in the execution of a given assay. For example, taq polymerase can bear a reagent role or an evaluant role. In a DNA sequencing assay aimed at generating sequence data about some plasmid, the reagent role of the taq polymerase is realized. In an assay to evaluate the quality of the taq polymerase itself, the evaluant/study subject role of the taq is realized, but not the reagent role since the taq is the subject about which data is generated.
In regard to the statement that reagents are 'distinct' from the specified outputs of a technique: note that a reagent may be incorporated into a material output of a technique, as long as the IDENTITY of this output is distinct from that of the bearer of the reagent role. For example, dNTPs input into a PCR are reagents that become part of the material output of this technique, but this output has a new identity (ie that of a 'nucleic acid molecule') that is distinct from the identity of the dNTPs that comprise it. Similarly, a biotin molecule input into a cell labeling technique are reagents that become part of the specified output, but the identity of the output is that of some modified cell specimen which shares identity with the input unmodified cell specimen, and not with the biotin label. Thus, we see that an important criteria of 'reagent-ness' is that it is a facilitator, and not the primary focus of an investigation or material processing technique (ie not the specified subject/evaluant about which knowledge is sought, or the specified output material of the technique).</rdfs:comment>
<rdfs:label xml:lang="en">reagent</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001880 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001880">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000245"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0001688"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001889"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000245"/>
<obo:IAO_0000111 xml:lang="en">organization of specimen provider principal investigator</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An organization that is the affiliation of the principal investigator providing the specimens for the investigation</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<obo:OBI_0001886>Sample Provider PI's Institution</obo:OBI_0001886>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">organization of specimen provider principal investigator</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001881 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001881">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000245"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0001688"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001883"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000245"/>
<obo:IAO_0000111 xml:lang="en">organization of Bioinformatics Resource Center contact person</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An organization that is the affiliation of the person who is contact representative of a Bioinformatics Resource Center</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<obo:OBI_0001886>Bioinformatics Resource Center Contact's Institution</obo:OBI_0001886>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">organization of Bioinformatics Resource Center contact person</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001882 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001882">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000104"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000423"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0302884"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100051"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">target material in specimen specification</obo:IAO_0000111>
<obo:IAO_0000112>Some examples of target material are Genome, Purified chromosome, Transcriptome, Phenotype, Proteome.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A plan specification which specifies the type of material that will be assayed in an investigation.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<obo:OBI_0001886>Target Material</obo:OBI_0001886>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">target material in specimen specification</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001883 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001883">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000846"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001626"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001687"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
<obo:IAO_0000111 xml:lang="en">Bioinformatics Resource Center contact person</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A person who is the contact representative of a Bioinformatics Resource Center</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<obo:OBI_0001886>Bioinformatics Resource Center Contact Name</obo:OBI_0001886>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">Bioinformatics Resource Center contact person</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001884 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001884">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000104"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000295"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">specimen-based scope of investigation specification</obo:IAO_0000111>
<obo:IAO_0000112>Some examples of specimen scope are Monoisolate, Multiisolate, Multi-species, Environment, or Synthetic.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A plan specification which specifies the scope of an investigation based on the heterogeneity of organisms or type of material that are the specified input of specimen collection.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<obo:OBI_0001886>Sample Scope</obo:OBI_0001886>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">specimen-based scope of investigation specification</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001885 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001885">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000245"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000947"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001557"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100051"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000245"/>
<obo:IAO_0000111 xml:lang="en">specimen repository organization</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An organization that provides a service to store and distribute specimens</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<obo:OBI_0001886>Specimen Repository</obo:OBI_0001886>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">specimen repository organization</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001887 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001887">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000429"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001883"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000429"/>
<obo:IAO_0000111 xml:lang="en">email address of Bioinformatics Resource Center contact person</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An email address of the person who is contact representative of a Bioinformatics Resource Center</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<obo:OBI_0001886>Bioinformatics Resource Center Contact's email</obo:OBI_0001886>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">email address of Bioinformatics Resource Center contact person</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001888 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001888">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000846"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001891"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001687"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
<obo:IAO_0000111 xml:lang="en">sequencing facility contact person</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A person who is the contact representative at the sequencing facility</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<obo:OBI_0001886>Sequencing Facility Contact Name</obo:OBI_0001886>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">sequencing facility contact person</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001889 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001889">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000646"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100051"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000103"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
<obo:IAO_0000111 xml:lang="en">specimen provider principal investigator</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A person who is a principal investigator and provides the specimen</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<obo:OBI_0001886>Sample Provider Principal Investigator (PI) Name</obo:OBI_0001886>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">specimen provider principal investigator</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001890 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001890">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000429"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001895"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000429"/>
<obo:IAO_0000111 xml:lang="en">email address of specimen collector</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An email address of the person collecting the specimen</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<obo:OBI_0001886>Specimen Collector's email</obo:OBI_0001886>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">email address of specimen collector</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001891 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001891">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000245"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000947"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001904"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002198"/>
<obo:IAO_0000111 xml:lang="en">sequencing facility organization</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An organization that provides sequence determination service</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<obo:OBI_0001886>Sequencing Facility</obo:OBI_0001886>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">sequencing facility organization</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001892 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001892">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000005"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000027"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0200000"/>
</owl:unionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">specification of data to be generated in an investigation</obo:IAO_0000111>
<obo:IAO_0000112>Some examples of Project Objectives are Raw sequence reads, Sequence, Analysis, Assembly, Annotation, Variation, Epigenetic markers, expression, maps, phenotype</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An objective specification which indicates the type of data that will be generated and submitted to a database.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<obo:OBI_0001886>Project Objectives</obo:OBI_0001886>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">specification of data to be generated in an investigation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001893 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001893">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000245"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0001688"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001895"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000245"/>
<obo:IAO_0000111 xml:lang="en">organization of specimen collector</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An organization that is the affiliation of the person collecting the specimen</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<obo:OBI_0001886>Specimen Collector's Institution</obo:OBI_0001886>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">organization of specimen collector</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001894 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001894">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000429"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001888"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000429"/>
<obo:IAO_0000111 xml:lang="en">email address of sequencing facility contact person</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An email address of the contact representative at the sequencing facility</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<obo:OBI_0001886>Sequencing Facility Contact's email</obo:OBI_0001886>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">email address of sequencing facility contact person</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001895 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001895">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001769"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
<obo:IAO_0000111 xml:lang="en">specimen collector</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A person who collects the specimen</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<obo:OBI_0001886>Specimen Collector Name</obo:OBI_0001886>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">specimen collector</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001896 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001896">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000104"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">investigation assay specification</obo:IAO_0000111>
<obo:IAO_0000112>Some examples of Project Method are Sequence, Array, Mass Spectrometry</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A plan specification which indicates the assay type used to obtain data.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<obo:OBI_0001886>Project Method</obo:OBI_0001886>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">investigation assay specification</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001897 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001897">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000245"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0001688"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001888"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000245"/>
<obo:IAO_0000111 xml:lang="en">organization of sequencing facility contact person</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An organization that is the affiliation of the contact representative at the sequencing facility</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<obo:OBI_0001886>Sequencing Facility Contact's Institution</obo:OBI_0001886>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">organization of sequencing facility contact person</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001898 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001898">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000300"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000066"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000066"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000066"/>
</owl:Restriction>
</owl:unionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000300"/>
<obo:IAO_0000111 xml:lang="en">comment on investigation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A textual entity that is about any of the aspects of an investigation worth noting</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<obo:OBI_0001886>Comments</obo:OBI_0001886>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">comment on investigation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001899 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001899">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000104"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100051"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">target capture specification</obo:IAO_0000111>
<obo:IAO_0000112>Some examples of target capture are Whole, CloneEnds, Exome, TargetedLocusLoci, RandomSurvey</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A plan specification which specifies how the material enrichment procedure will influence the scale, or type of material that will be assayed in the specimen.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<obo:OBI_0001886>Target Capture</obo:OBI_0001886>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">target capture specification</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001900 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001900">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001885"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001616"/>
<obo:IAO_0000111 xml:lang="en">specimen identifier assigned by specimen repository</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen identifier which is assigned by a specimen repository</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<obo:OBI_0001886>Specimen Repository Sample ID</obo:OBI_0001886>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">specimen identifier assigned by specimen repository</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001901 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001901">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001616"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001891"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001616"/>
<obo:IAO_0000111 xml:lang="en">specimen identifier assigned by sequencing facility</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen identifier which is assigned by a sequencing facility</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<obo:OBI_0001886>Sample ID - Sequencing Facility</obo:OBI_0001886>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">specimen identifier assigned by sequencing facility</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001902 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001902">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:someValuesFrom>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33696"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100051"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000295"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600047"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000073"/>
<obo:IAO_0000111 xml:lang="en">sample preparation for sequencing assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A sample preparation for assay that preparation of nucleic acids for a sequencing assay</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<obo:OBI_0001886>Nucleic Acid Preparation Method</obo:OBI_0001886>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">sample preparation for sequencing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001903 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001903">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000429"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001889"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000429"/>
<obo:IAO_0000111 xml:lang="en">email address of specimen provider principal investigator</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An email address of the principal investigator providing the specimens for the investigation</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<obo:OBI_0001886>Sample Provider PI's email</obo:OBI_0001886>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">email address of specimen provider principal investigator</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001904 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001904">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001528"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000107"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600047"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001547"/>
<obo:IAO_0000111 xml:lang="en">sequencing service</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A service provides sequencing service which is the realization of some sequencing such as RNA and DNA sequencing in which the service provider role is realized.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>Adpated from 'DNA sequencing service'</obo:IAO_0000119>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">sequencing service</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001905 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001905">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0100060"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600037"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001866"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001866"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>secondary cultured cell population</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cultured cell population that is derived through one or more passages in culture.</obo:IAO_0000115>
<obo:IAO_0000116>The term 'secondary cell culture' is generally used in biological texts/protocols to refer to any culture of cells following an initial passage. We include it here because there are often a number of passages between a primary culture and the establishment of a stable, homogenous cell line. Such cultures are considered to be 'secondary cultures' but not 'cell lines' during this intermediate passaging/selection period between their derivation from a 'primary cell culture' and derivation into a 'cell line', which is a more specific type of secondary culture.</obo:IAO_0000116>
<obo:IAO_0000117>PERSON:Matthew Brush</obo:IAO_0000117>
<obo:IAO_0000118>secondary cell culture sample</obo:IAO_0000118>
<obo:IAO_0000119>PERSON:Matthew Brush</obo:IAO_0000119>
<rdfs:comment>The concept of a 'secondary cultured cell population' covers cell lines as well as cultured cell populations more immediately derived from a primary culture which have yet to achieve adequate genetic stability and compositional homogeneity to be considered a cell line. The extent of the collection of cells in a 'secondary cultured cell population' is restricted only in that all cell members must share a propagation history (ie be derived through a common lineage of passages from an initial culture). Secondary cultured cell populations can be under active culture, stored in a quiescent state for future use, or applied experimentally.</rdfs:comment>
<rdfs:label>secondary cultured cell population</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001906 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001906">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CLO_0009828"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000867"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>cancer cell line</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An immortal cell line derived from a transformed cell that was part of a malignant tumor.</obo:IAO_0000115>
<rdfs:label>cancer cell line</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001907 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001907">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600043"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CLO_0000001"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>immortalizing cell line transformation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000115 xml:lang="en">a genetic transformation of a cell line cell with transgenic constructs intended to confer the capability for indefinite propagation in culture</obo:IAO_0000115>
<rdfs:label>immortalizing cell line transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001908 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001908">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
<obo:IAO_0000111>testable hypothesis</obo:IAO_0000111>
<obo:IAO_0000112>that fucoidan has a small statistically significant effect on AT3 level but no useful clinical effect as in-vivo anticoagulant, a paraphrase of part of the last paragraph of the discussion section of the paper 'Pilot clinical study to evaluate the anticoagulant activity of fucoidan', by Lowenthal et. al.PMID:19696660</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An information content entity that expresses an assertion that is intended to be tested.</obo:IAO_0000115>
<obo:IAO_0000116>In the Philly 2013 workshop, we recognized the limitations of "hypothesis textual entity", and we introduced this as more general. The need for the 'textual entity' term going forward is up for future debate.</obo:IAO_0000116>
<obo:IAO_0000117>Group:2013 Philly Workshop group</obo:IAO_0000117>
<obo:IAO_0000118>hypothesis</obo:IAO_0000118>
<obo:IAO_0000119>Group:2013 Philly Workshop group</obo:IAO_0000119>
<rdfs:label>testable hypothesis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001909 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001909">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000124"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000338"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>conclusion based on data</obo:IAO_0000111>
<obo:IAO_0000112>The conclusion that a gene is upregulated in a tissue sample based on the band intensity in a western blot. The conclusion that a patient has a infection based on measurement of an elevated body temperature and reported headache. The conclusion that there were problems in an investigation because data from PCR and microarray are conflicting.
The following are NOT conclusions based on data: data themselves; results from pure mathematics, e.g. "13 is prime".</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An information content entity that is inferred from data.</obo:IAO_0000115>
<obo:IAO_0000116>In the Philly 2013 workshop, we recognized the limitations of "conclusion textual entity", and we introduced this as more general. The need for the 'textual entity' term going forward is up for future debate.</obo:IAO_0000116>
<obo:IAO_0000117>Group:2013 Philly Workshop group</obo:IAO_0000117>
<obo:IAO_0000119>Group:2013 Philly Workshop group</obo:IAO_0000119>
<rdfs:label>conclusion based on data</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001910 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001910">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001876"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000001"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>primary cell culture</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cell culture comprised of primary cultured cells and the media in which they are being actively propaged or quiescently stored.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Matthew Brush</obo:IAO_0000117>
<obo:IAO_0000119>OBI-CLO Alignment Working Group (Spring 2013)</obo:IAO_0000119>
<rdfs:label xml:lang="en">primary cell culture</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001911 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001911">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001876"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CLO_0000001"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>cell line culture</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cell culture comprised of cell line cells and the media in which they are being actively propagated or quiescently stored.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Matthew Brush</obo:IAO_0000117>
<obo:IAO_0000119>OBI-CLO Alignment Working Group (Spring 2013)</obo:IAO_0000119>
<rdfs:comment>A cell line culture includes the cells in culture, as well as the media and all additives/reagents in which the cells are being grown or in which they are stored.</rdfs:comment>
<rdfs:label xml:lang="en">cell line culture</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001912 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001912">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<obo:IAO_0000111>cell freezing medium</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A processed material that serves as a liquid vehicle for freezing cells for long term quiescent stroage, which contains chemicls needed to sustain cell viability across freeze-thaw cycles.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Matthew Brush</obo:IAO_0000117>
<rdfs:label xml:lang="en">cell freezing medium</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001913 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001913">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000416"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000413"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200000"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">computation run time</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Gigascience. 2012 Dec 27;1(1):18. doi: 10.1186/2047-217X-1-18.
PMID: 23587118.
See Table 4</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">computation run time is a time measurement datum which corresponds the time expressed in second, minute, hour necessary for a computer program to complete a process execution, for example genome assembly. It is an important metrics as it indicates the resource occupancy and computer program efficiency.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Alejandra Gonzalez-Beltran</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">computation run time datum</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">PRS,AGB</obo:IAO_0000119>
<rdfs:label xml:lang="en">computation run time</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001914 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001914">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000415"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0302892"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">multiplex ligation-mediated amplification</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A polymerase chain reaction that amplifies multiple targets with a single primer pair mediated by hybridization of a primer with its target sequence using ligation.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000118>LMA</obo:IAO_0000118>
<obo:IAO_0000118>MLPA</obo:IAO_0000118>
<obo:IAO_0000118>Multiplex ligation-dependent probe amplification</obo:IAO_0000118>
<obo:IAO_0000119>web: http://en.wikipedia.org/wiki/Multiplex_Ligation-dependent_Probe_Amplification
Pubmed: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1867615/</obo:IAO_0000119>
<rdfs:label xml:lang="en">multiplex ligation-mediated amplification</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001915 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001915">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002692"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
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<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000117>Venkat Malladi</obo:IAO_0000117>
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<obo:IAO_0000118>miRNA-seq</obo:IAO_0000118>
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<obo:IAO_0000118>microRNA-seq assay</obo:IAO_0000118>
<obo:IAO_0000119>url:http://www.ebi.ac.uk/efo/EFO_0002896</obo:IAO_0000119>
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<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000117>Venkat Malladi</obo:IAO_0000117>
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<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
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</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000101"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/SO_0000276"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>microRNA profiling assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A transcription profiling assay that quantifies the microRNA species within a biological sample.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000117>Venkat Malladi</obo:IAO_0000117>
<obo:IAO_0000118>miRNA expression assay</obo:IAO_0000118>
<obo:IAO_0000118>microRNA expression assay</obo:IAO_0000118>
<obo:IAO_0000119>PMID: 23382819</obo:IAO_0000119>
<rdfs:label>microRNA profiling assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001928 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001928">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000059"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001755"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<obo:IAO_0000111 xml:lang="en">selection</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PMID: 24023800. In this study, a set of eleven genes (VATP16, 60 S, UQCC, SMD3, EF1α, UBQ, SAND, GAPDH, ACT, PsaB, PTB2) was evaluated to identify reference genes during the first hours of interaction (6, 12, 18 and 24 hpi) between two V. vinifera genotypes and P. viticola. Two analyses were used for the selection of reference genes: direct comparison of susceptible, Trincadeira, and resistant, Regent, V. vinifera cultivars at 0 h, 6, 12, 18 and 24 hours post inoculation with P. viticola (genotype effect); and comparison of each genotype with mock inoculated samples during inoculation time-course (biotic stress effect). Three statistical methods were used, GeNorm, NormFinder, and BestKeeper, allowing to identify UBQ, EF1α and GAPDH as the most stable genes for the genotype effect.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A planned process with the objective to create a group of entities by applying a predefined criteria to a larger group of entities.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">this term refers to a planned process and therefore is distinct from the notion of 'natural selection', a process covering the operation of natural causes by which those individuals of a species that are best adapted to the environment tend to be preserved and to transmit their characters, while those less adapted die out, so that in the course of generations the degree of adaptation to the environment tends progressively to increase. (as defined by Oxford English Dictionary)</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Person: Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">selection process</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">selection</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001929 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001929">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001931"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0001927"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000125"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000039"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UO_0000002"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>mass value specification</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A value specification that specifies the mass of some thing.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Bjoern Peters</obo:IAO_0000117>
<rdfs:label>mass value specification</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001930 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001930">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001933"/>
<obo:IAO_0000111>categorical value specification</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A value specification that is specifies one category out of a fixed number of nominal categories</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Bjoern Peters</obo:IAO_0000117>
<rdfs:label>categorical value specification</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001931 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001931">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001933"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000039"/>
<owl:minCardinality rdf:datatype="http://www.w3.org/2001/XMLSchema#nonNegativeInteger">1</owl:minCardinality>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0001937"/>
<owl:minCardinality rdf:datatype="http://www.w3.org/2001/XMLSchema#nonNegativeInteger">1</owl:minCardinality>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>scalar value specification</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A value specification that consists of two parts: a numeral and a unit label</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Bjoern Peters</obo:IAO_0000117>
<rdfs:label>scalar value specification</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001932 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001932">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000015"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001934"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001934"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>comparing prediction to measurement</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A planned process in which predicted values for some thing are compared to measured values for that thing.</obo:IAO_0000115>
<rdfs:label>comparing prediction to measurement</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001933 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001933">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
<obo:IAO_0000111>value specification</obo:IAO_0000111>
<obo:IAO_0000112>The value of 'positive' in a classification scheme of "positive or negative"; the value of '20g' on the quantitative scale of mass.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An information content entity that specifies a value within a classification scheme or on a quantitative scale.</obo:IAO_0000115>
<obo:IAO_0000116>This term is currently a descendant of 'information content entity', which requires that it 'is about' something. A value specification of '20g' for a measurement data item of the mass of a particular mouse 'is about' the mass of that mouse. However there are cases where a value specification is not clearly about any particular. In the future we may change 'value specification' to remove the 'is about' requirement.</obo:IAO_0000116>
<obo:IAO_0000117>PERSON:Bjoern Peters</obo:IAO_0000117>
<rdfs:label>value specification</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001934 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001934">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001933"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000104"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000059"/>
<owl:allValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001932"/>
</owl:Restriction>
</owl:allValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>predicted value</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">an information content entity that has been generated by a prediction process in which an estimate of a value of an entity is made which can be measured but without performing such a measurement. The value specification is intended to be close to the value a measurement process would produce modulo a prediction error.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Bjoern Peters</obo:IAO_0000117>
<rdfs:label>predicted value</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001935 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001935">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001934"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001929"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001934"/>
<obo:IAO_0000111>predicted mass value</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A predicted value where the prediction specifies the mass of some thing.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Bjoern Peters</obo:IAO_0000117>
<rdfs:label>predicted mass value</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001936 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001936">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002744"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600038"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<obo:IAO_0000111>molecular-labeled material</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">a material entity that is the specified output of an addition of molecular label process that aims to label some molecular target to allow for its detection in a detection of molecular label assay</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Matthew Brush</obo:IAO_0000117>
<obo:IAO_0000119>OBI developer call, 3-12-12</obo:IAO_0000119>
<rdfs:label>molecular-labeled material</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001939 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001939">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/SO_0001248"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001872"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>genome coverage</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Gigascience. 2012 Dec 27;1(1):18. doi: 10.1186/2047-217X-1-18.
PMID: 23587118.
"The genome coverage increased from 81.16% to 93.91%"</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A data item that is the total number of bases in reads, divided by genome size, assumed to be the reference size (for instance of 3.10 Gb for human and 2.73 Gb for mouse) and refers to the percentage of the genome that is contained in the assembly based on size estimates; these are usually based on cytological techniques. Genome coverage of 90–95% is generally considered to be good, as most genomes contain a considerable fraction of repetitive regions that are difficult to sequence. So it is not a cause for concern if the genome coverage of an assembly is a bit less than 100%.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Alejandra Gonzalez-Beltran</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">A beginner's guide to eukaryotic genome annotation. Yandell M, Ence D.
Nat Rev Genet. 2012 Apr 18;13(5):329-42. doi: 10.1038/nrg3174.
PMID: 22510764</obo:IAO_0000119>
<rdfs:label>genome coverage</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001940 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001940">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000032"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000039"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000003"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/SO_0001248"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001872"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">N50</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Gigascience. 2012 Dec 27;1(1):18. doi: 10.1186/2047-217X-1-18.
PMID: 23587118.
"Here, the contig and scaffold N50 of the YH genome were ~20.9 kbp and ~22 Mbp"</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">the weighted median item size or N50 is a weighted median of the lengths of items, equal to the length of the longest item i such that the sum of the lengths of items greater than or equal in length to i is greater than or equal to half the length of all of the items. With regard to assemblies the items are typically contigs or scaffolds. It therefore denotes the ability of the software to create contigs and provides information about the resulting sequence assembly</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Alejandra Gonzalez-Beltran</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">weighted median item size</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">adapted from:
"http://genome.cshlp.org/content/21/12/2224.full?sid=74019122-f944-4ccc-bffe-d16fdd0e7d6c"
(from table 7)
and from "http://www.nature.com/nrg/journal/v14/n3/full/nrg3367.html"</obo:IAO_0000119>
<rdfs:label xml:lang="en">N50</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001941 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001941">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001940"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/SO_0000149"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001872"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">contig N50</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Gigascience. 2012 Dec 27;1(1):18. doi: 10.1186/2047-217X-1-18.
PMID: 23587118.
"Here, the contig and scaffold N50 of the YH genome were ~20.9 kbp and ~22 Mbp"</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">N50 statistic computed for the contigs produced by the assembly process. A contig N50 is calculated by first ordering every contig by length from longest to shortest. Next, starting from the longest contig, the lengths of each contig are summed, until this running sum equals one-half of the total length of all contigs in the assembly. The contig N50 of the assembly is the length of the shortest contig in this list.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Alejandra Gonzalez-Beltran</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">adapted from: nature:http://www.nature.com/nrg/journal/v13/n5/box/nrg3174_BX1.html</obo:IAO_0000119>
<rdfs:label xml:lang="en">contig N50</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001942 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001942">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000245"/>
<obo:IAO_0000111 xml:lang="en">grant agency</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An organization that provides funding support for projects such as investigations.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Jie Zheng, Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000118>funding organization</obo:IAO_0000118>
<obo:IAO_0000119>NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">grant agency</rdfs:label>
<rdfs:seeAlso>'funding organization'
http://vivoweb.org/ontology/core#FundingOrganization</rdfs:seeAlso>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001943 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001943">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000104"/>
<obo:IAO_0000111 xml:lang="en">software pipeline</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A plan specification that specifies a chain encoded in software of processing elements (processes, threads, coroutines, etc.), arranged so that the output of each element is the input of the next. Usually some amount of buffering is provided between consecutive elements.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Jie Zheng, Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>WEB: http://en.wikipedia.org/wiki/Pipeline_%28software%29</obo:IAO_0000119>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">software pipeline</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001944 -->
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<obo:IAO_0000111 xml:lang="en">sequence annotation</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A planned process that identifies and reports sequence features (e.g. protein coding regions) in sequence data.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Jie Zheng, Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
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<!-- http://purl.obolibrary.org/obo/OBI_0001945 -->
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<obo:IAO_0000111 xml:lang="en">scaffold N50</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Gigascience. 2012 Dec 27;1(1):18. doi: 10.1186/2047-217X-1-18.
PMID: 23587118.
"Here, the contig and scaffold N50 of the YH genome were ~20.9 kbp and ~22 Mbp"</obo:IAO_0000112>
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<obo:IAO_0000115 xml:lang="en">N50 statistic computed for the scaffold produced by the assembly process. The method for computing the value is similar to that of contig N50 but uses scaffold information instead of contig information</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Alejandra Gonzalez-Beltran</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">adapted from: nature:http://www.nature.com/nrg/journal/v13/n5/box/nrg3174_BX1.html</obo:IAO_0000119>
<rdfs:label xml:lang="en">scaffold N50</rdfs:label>
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<obo:IAO_0000111 xml:lang="en">forward PCR primer</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">SP6 promoter, forward primer (SP6 TTTAGGTGACACTATAG)</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A short oligonucleotide complementary to target DNA (5'->3' on plus strand) that acts as the leader for DNA extension in a PCR reaction. The polymerase starts replication at the 3'-end of the primer, and copies the opposite strand. A primer is characterized by its 'melting temperature' (Tm) and pairs of primers should have similar Tm.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">5' primer</obo:IAO_0000118>
<obo:IAO_0000118 xml:lang="en">forward primer</obo:IAO_0000118>
<obo:IAO_0000118 xml:lang="en">sense primer</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">adapted from http://www.ncbi.nlm.nih.gov/projects/genome/probe/doc/Glossary.shtml#p</obo:IAO_0000119>
<rdfs:label xml:lang="en">forward PCR primer</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001947 -->
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<obo:IAO_0000115 xml:lang="en">A person or organization reporting the feature annotation results from the analysis of a macromolecular sequence.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Jie Zheng, Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<obo:OBI_0001886>annotation provider</obo:OBI_0001886>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">sequence annotation provider</rdfs:label>
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<obo:IAO_0000115 xml:lang="en">A textual entity that is used to denote a sequence assembly.</obo:IAO_0000115>
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<obo:IAO_0000119>NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
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<rdfs:label xml:lang="en">sequence assembly name</rdfs:label>
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<obo:IAO_0000115 xml:lang="en">A reporting party role that is realized by a person or organization who reports the feature annotation results from the analysis of a macromolecular sequence.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Jie Zheng, Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>NIAID GSCID-BRC metadata working group</obo:IAO_0000119>
<dc:source>NIAID GSCID-BRC</dc:source>
<rdfs:label xml:lang="en">sequence annotation reporting role</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001951 -->
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<obo:IAO_0000111 xml:lang="en">reverse PCR primer</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en"></obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">5' end of luciferase, reverse primer (LucNrev CCTTATGCAGTTGCTCTCC)</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A short oligonucleotide complementary to target DNA (5'->3' on minus strand) that acts as the leader for DNA extension in a PCR reaction. The polymerase starts replication at the 3'-end of the primer, and copies the opposite strand. A primer is characterized by its 'melting temperature' (Tm) and pairs of primers should have similar Tm.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">3' primer</obo:IAO_0000118>
<obo:IAO_0000118 xml:lang="en">antisense primer</obo:IAO_0000118>
<obo:IAO_0000118 xml:lang="en">reverse primer</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">adapted from "http://www.ncbi.nlm.nih.gov/projects/genome/probe/doc/Glossary.shtml#p"</obo:IAO_0000119>
<rdfs:label xml:lang="en">reverse PCR primer</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001952 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001952">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001953"/>
<obo:IAO_0000111 xml:lang="en">flash freezing</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A freezing process by which material entities are quickly frozen by subjecting them to cryogenic temperatures, or in direct contact with Liquid nitrogen at -320.8F or -196°C.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Mathias Brochhausen, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>WEB: http://en.wikipedia.org/wiki/Flash_freezing</obo:IAO_0000119>
<rdfs:label xml:lang="en">flash freezing</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001953 -->
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<obo:IAO_0000111 xml:lang="en">freezing</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A planned process with the objective to bring some material entity to a temperature below its freezing point.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Mathias Brochhausen, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>Mathias Brochhausen</obo:IAO_0000119>
<rdfs:label xml:lang="en">freezing</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001954 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>ChIP assay</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 6379641</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An assay in which portions of chromatin, the ordered and organized complex of DNA and its interaction partners that make up a chormosome, is extracted and purified by immunoprecipitation with antibodies or tags, and subsequently analyzed</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>chromatin immunoprecipitation assay</obo:IAO_0000118>
<obo:IAO_0000119>url:https://en.wikipedia.org/wiki/Chromatin_immunoprecipitation</obo:IAO_0000119>
<rdfs:label>ChIP assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001955 -->
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<obo:IAO_0000111>competitive binding reference ligand role</obo:IAO_0000111>
<obo:IAO_0000112>The role of a radiolabeled peptide that is known to bind to the MHC molecule HLA-A*02:01 with high affinity when it is used in a competitive binding assay in which another peptide of interest is tested for its ability to outcompete binding of the labeled peptide in a dose dependent fashion.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A positive reference substance role that inheres in a material entity that is known to bind to a target entity, and that is realized in a competitive binding assay that has as specified input the target entity, an evaluant and the positive reference substance, where the binding of the evaluant to the target is measured based on the evaluant's ability to compete with the positive reference substance for binding to the target.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters, Randi Vita, James A. Overton</obo:IAO_0000117>
<obo:IAO_0000119>Bjoern Peters</obo:IAO_0000119>
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<!-- http://purl.obolibrary.org/obo/OBI_0001956 -->
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<obo:IAO_0000111>assay using chromatin immunoprecipitation</obo:IAO_0000111>
<obo:IAO_0000112>http://www.lifetechnologies.com/uk/en/home/life-science/epigenetics-noncoding-rna-research/chromatin-remodeling/chromatin-immunoprecipitation-chip.html</obo:IAO_0000112>
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<obo:IAO_0000115 xml:lang="en">An assay that produces data about protein-DNA interaction or DNA epigenetic modification using immunoprecipitation</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000233>http://sourceforge.net/p/obi/obi-terms/707/</obo:IAO_0000233>
<rdfs:label>assay using chromatin immunoprecipitation</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0001957 -->
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<obo:IAO_0000111>hardware testing design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design that aims to compare different types of hardware for performance, reproducibility, accuracy and precision.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>MO_734 hardware_variation_design</obo:IAO_0000119>
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<!-- http://purl.obolibrary.org/obo/OBI_0001958 -->
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Nat Methods. 2014 Aug;11(8):834-40. doi: 10.1038/nmeth.3022. Epub 2014 Jul 6.
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<!-- http://purl.obolibrary.org/obo/OBI_0001976 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001976">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002162"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000086"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_29237"/>
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</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_29237"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>hydrogen/deuterium exchange footprinting assay</obo:IAO_0000111>
<obo:IAO_0000112>Performing deuterium exchange on a protein by itself and in the presence of a binding partner, degrading the protein into peptide segments and identifying where deuterium exchange occurred by detecting the peptides in Mass Spectrometry. Peptides that have a modified deuteration pattern when the protein was bound to a partner are expected to be part of the binding interface.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A footprinting assay that uses a chemical reaction whereby a covalently bonded hydrogen atom is replaced by a deuterium atom, or vice versa in order to gather information about the solvent accessibility of parts of a molecule and thus its tertiary structure.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>hydrogen/deuterium exchange footprinting assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001977 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001977">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000000"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>cytometry assay</obo:IAO_0000111>
<obo:IAO_0000112>An intracellular material detection by flow cytometry assay measuring peforin inside a culture of T cells.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that counts and/or measures characteristics of cells.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>cytometry assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001978 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001978">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001121"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001121"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600053"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>immunoblot assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that detects specific molecules in an input material by separating it using gel electrophoresis, transfering the separated molecules to a membrane, and staining them with_ antibodies specific to the analyte molecules.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>immunoblot assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001979 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001979">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001499"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001501"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003368"/>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>fluorescence quenching binding assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A binding assay in which the proximity of two entities is monitored by measuring a fluorescent signal of one of the entities that gets reduced if the two entities are cliose to each other.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>fluorescence quenching binding assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001980 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001980">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100026"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>in vivo intervention experiment</obo:IAO_0000111>
<obo:IAO_0000112>Comparing the level of allergy symptoms in humans before and post allergy immunotherapy. Testing if injection of a chemical compound into mice will lead to decreased survival.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay in which the effect of a targeted process (the intervention) on an organism is tested.</obo:IAO_0000115>
<obo:IAO_0000116>The intervention in an experiment should be modeled accordingly to the intevention carried out in a human cllinical trial, which is currently modeled as 'study intervention'. This touches the boundaries of study vs. assay.</obo:IAO_0000116>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>in vivo intervention experiment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001981 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001981">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001980"/>
<obo:IAO_0000111>disease exacerbation in vivo intervention experiment</obo:IAO_0000111>
<obo:IAO_0000112>Injecting a set of mice with a peptide and measuring symtoms to determine if their disease course was more severe than the disease course of a set of mice that were not injected with the same peptide.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An in vivo intervention experiment that tests the ability of the intervention to increase the severity of a disease in the host.</obo:IAO_0000115>
<obo:IAO_0000116>Should have data about disease severity as readout; could just use disease for now</obo:IAO_0000116>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>disease exacerbation in vivo intervention experiment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001982 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001982">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001980"/>
<obo:IAO_0000111>protection from challenge in vivo intervention experiment</obo:IAO_0000111>
<obo:IAO_0000112>Injecting a set of mice with a peptide and measuring symtoms to determine if their disease course was less severe than the disease course of a set of mice that were not injected with the same peptide.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An in vivo intervention experiment that tests the ability of the intervention to prevent occurrence of a disease in a host.</obo:IAO_0000115>
<obo:IAO_0000116>should have challenge as intervention</obo:IAO_0000116>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>protection from challenge in vivo intervention experiment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001983 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001983">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001980"/>
<obo:IAO_0000111>tolerance induction intervention experiment</obo:IAO_0000111>
<obo:IAO_0000112>Injecting a set of mice with a Der p 2 peptide and measuring the IL-2 response of T cells from those mice when exposed to the Der p 2 protein in vitro to determine if those T cells made less IL-2 than cells taken from mice which were not injected with the same Der p 2 peptide.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An in vivo intervention experiment that tests the ability of the intervention to decrease an immune response.</obo:IAO_0000115>
<obo:IAO_0000116>should have tolerance induction as intervention</obo:IAO_0000116>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>tolerance induction intervention experiment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001984 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001984">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001980"/>
<obo:IAO_0000111>treatment intervention experiment</obo:IAO_0000111>
<obo:IAO_0000112>Testing if administering oral histamine-blockers will reduce the number of emergency room visits in severely asthmatic individuals.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An in vivo intervention experiment in which the ability of the intervention to reduce or cure the effects of a disease are tested.</obo:IAO_0000115>
<obo:IAO_0000116>should have treatment as intervention</obo:IAO_0000116>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>treatment intervention experiment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001985 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001985">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400147"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400147"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<obo:IAO_0000111>microarray assay</obo:IAO_0000111>
<obo:IAO_0000112>Measuring if sera from an influenza A virus immunizedmouse binds to Hemagglutinin protein that is immobilized on a microarray.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay where binding of the analyte to immobilized matrix is measured.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>microarray assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001986 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001986">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001632"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002743"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001632"/>
<obo:IAO_0000111>immunohistochemistry</obo:IAO_0000111>
<obo:IAO_0000112>Staining a brain tissue sample from an Alzheimer's disease patient with antibodies to amyloid beta to identify amyloid plaques.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An immunostaining assay to detect and potentially localize antigens within the cells of a tissue section.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>immunohistochemistry</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001987 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001987">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001548"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001503"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000039"/>
<owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/UO_0000285"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001553"/>
<obo:IAO_0000111>assay measuring the association constant [KA] of a MHC:ligand complex</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A MHC binding constant determination assay measuring equilibrium association constant (KA).</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>association constant KA|binding assay|1/M</obo:OBI_9991118>
<rdfs:label>assay measuring the association constant [KA] of a MHC:ligand complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001988 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001988">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
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<obo:IAO_0000112>Wang J, Qi J, Zhao H, He S, Zhang Y, Wei S, Zhao F. Metagenomic sequencing reveals microbiota and its functional potential associated with periodontal disease. Sci Rep. 2013 May;3:1843. PMID:23673380</obo:IAO_0000112>
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<obo:IAO_0000112>Spaethling, Jennifer M., and James H. Eberwine. "Single-cell transcriptomics for drug target discovery." Current opinion in pharmacology (2013). pmid:23725882</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A DNA sequencer which is manufactured by the Illumina corporation, with two flow cells and a throughput of up to 160 Gb per day. Built upon sequencing by synthesis technology, the machine is optimized for generation of data for batching multiple samples or rapid results on a few samples.</obo:IAO_0000115>
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<obo:IAO_0000111>Illumina MiSeq</obo:IAO_0000111>
<obo:IAO_0000112>Rutvisuttinunt W, Chinnawirotpisan P, Simasathien S, Shrestha SK, Yoon IK, Klungthong C, Fernandez S. Simultaneous and complete genome sequencing of influenza A and B with high coverage by Illumina MiSeq Platform. J Virol Methods. 2013 Nov;193(2):394-404. [PMID:23856301]</obo:IAO_0000112>
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<obo:IAO_0000115 xml:lang="en">A DNA sequencer which is manufactured by the Illumina corporation. Built upon sequencing by synthesis technology, the machine provides an end-to-end solution (cluster generation, amplification, sequencing, and data analysis) in a single machine.</obo:IAO_0000115>
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<obo:IAO_0000118>MiSeq</obo:IAO_0000118>
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<!-- http://purl.obolibrary.org/obo/OBI_0002004 -->
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<obo:IAO_0000112>Naumov, Vladimir A., et al. "Genome-scale analysis of DNA methylation in colorectal cancer using Infinium HumanMethylation450 BeadChips." Epigenetics 8.9 (2013): 0-1. PMID: 23867710</obo:IAO_0000112>
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<obo:IAO_0000115 xml:lang="en">A methylation BeadChip which is manufactured by the Illumina corporation. Built upon BeadChip tehcnology, the array interrogates ~ 485,000 methylation sites per sample at single-nucleotide resolution.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Venkat Malladi, Chris Stoeckert, Jie Zheng, Alan Ruttenberg</obo:IAO_0000117>
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<!-- http://purl.obolibrary.org/obo/OBI_0002005 -->
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<obo:IAO_0000112>Polidoro, Silvia, et al. "Effects of bisphosphonate treatment on DNA methylation in osteonecrosis of the jaw." Mutation Research/Genetic Toxicology and Environmental Mutagenesis 757.2 (2013): 104-113. PMID: 23892139</obo:IAO_0000112>
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<obo:IAO_0000115 xml:lang="en">A methylation BeadChip which is manufactured by the Illumina corporation. Built upon BeadChip tehcnology, the array interrogates ~ 27,000 CpG sites per sample at single-nucleotide resolution.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Venkat Malladi, Chris Stoeckert, Jie Zheng, Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000118>Illumina Infinium Human Methylation 27K BeadChip</obo:IAO_0000118>
<obo:IAO_0000119>http://res.illumina.com/documents/products/datasheets/datasheet_dna_methylation_analysis.pdf</obo:IAO_0000119>
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<!-- http://purl.obolibrary.org/obo/OBI_0002006 -->
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<obo:IAO_0000112>Edwards, Todd L., et al. "Genome-Wide Association Study Confirms SNPs in SNCA and the MAPT Region as Common Risk Factors for Parkinson Disease." Annals of human genetics 74.2 (2010): 97-109. PMID: 20070850</obo:IAO_0000112>
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<obo:IAO_0000115 xml:lang="en">A BeadChip which is manufactured by the Illumina corporation. Built upon BeadChip tehcnology, the array integrates ~ 1 million markers per sample for genotyping, and copy number variation (CNV) and Cytogenetic analysis.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Venkat Malladi, Chris Stoeckert, Jie Zheng, Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000118>Illumina Human 1M-Duo Infinium HD BeadChip</obo:IAO_0000118>
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<!-- http://purl.obolibrary.org/obo/OBI_0002007 -->
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<obo:IAO_0000111>SOLiD 3 Plus System</obo:IAO_0000111>
<obo:IAO_0000112>Vissers, Lisenka ELM, et al. "A de novo paradigm for mental retardation." Nature genetics 42.12 (2010): 1109-1112. PMID:21076407</obo:IAO_0000112>
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<obo:IAO_0000115 xml:lang="en">A DNA sequencer which is manufacted by the Applied Biosystems corporation. Built upon SOLiD sequencing technology, the machine generates greater than 1 billion mappable reads per run.</obo:IAO_0000115>
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<!-- http://purl.obolibrary.org/obo/OBI_0002008 -->
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<obo:IAO_0000112>Miller, Becky Akiko. Detection and biological assessment of genome structural variation in Plasmodium falciparum. Diss. University of Notre Dame, 2012. http://etd.nd.edu/ETD-db/theses/available/etd-04182012-114744/</obo:IAO_0000112>
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<obo:IAO_0000115 xml:lang="en">A tiling array which is manufactured by the Nimblegen corporation. Built to analyze DNA sequence copy number by comparative genomic hybridization for mouse DNA against 385,000 features.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Venkat Malladi, Chris Stoeckert, Jie Zheng, Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000118>Nimblegen Mouse 385K Whole Genome CGH Tiling Array</obo:IAO_0000118>
<obo:IAO_0000119>http://www.nimblegen.com/downloads/support/05434483001_NG_CGHLOH_UGuide_v9p1.pdf</obo:IAO_0000119>
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<!-- http://purl.obolibrary.org/obo/OBI_0002009 -->
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<obo:IAO_0000111>Mouse 3x720K Whole Genome CGH Tiling Array</obo:IAO_0000111>
<obo:IAO_0000112>Wartman, Lukas D., et al. "Sequencing a mouse acute promyelocytic leukemia genome reveals genetic events relevant for disease progression." The Journal of clinical investigation 121.4 (2011): 1445. PMID:21436584</obo:IAO_0000112>
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<obo:IAO_0000115 xml:lang="en">A tiling array which is manufactured by the Nimblegen corporation. Built to analyze DNA sequence copy number by comparative genomic hybridization for mouse DNA against 3x720,000 features.</obo:IAO_0000115>
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<obo:IAO_0000118>Nimblegen Mouse 3x720K Whole Genome CGH Tiling Array</obo:IAO_0000118>
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<!-- http://purl.obolibrary.org/obo/OBI_0002010 -->
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<!-- http://purl.obolibrary.org/obo/OBI_0002011 -->
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<obo:IAO_0000112>Filges, Isabel, et al. "Reduced expression by SETBP1 haploinsufficiency causes developmental and expressive language delay indicating a phenotype distinct from Schinzel–Giedion syndrome." Journal of medical genetics 48.2 (2011): 117-122. PMID:21037274</obo:IAO_0000112>
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<!-- http://purl.obolibrary.org/obo/OBI_0002012 -->
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<obo:IAO_0000111>PacBio RS II</obo:IAO_0000111>
<obo:IAO_0000112>Spaethling, Jennifer M., and James H. Eberwine. "Single-cell transcriptomics for drug target discovery." Current opinion in pharmacology (2013). pmid:23725882</obo:IAO_0000112>
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<obo:IAO_0000115 xml:lang="en">A DNA sequencer which is manufactured by the Pacific Biosciences corporation. Built upon single molecule real-time sequencing technology, the machine is optimized for generation with long reads and high consensus accuracy.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Venkat Malladi, Chris Stoeckert, Jie Zheng, Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000118>Pacific Biosciences RS II</obo:IAO_0000118>
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<!-- http://purl.obolibrary.org/obo/OBI_0002013 -->
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<obo:IAO_0000112>Kolbert, Christopher P., et al. "Multi-platform analysis of microRNA expression measurements in RNA from fresh frozen and FFPE tissues." PloS one 8.1 (2013): e52517. PMID:23382819</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A human array which is manufacutred by NanoString Technologies. Built upon color-coded molecular barcodes technology, the array profiles miRNA with increased specificity and sensitivty than microarrays.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Venkat Malladi, Chris Stoeckert, Jie Zheng, Alan Ruttenberg. Mark A. Miller removed "V2" per https://github.com/obi-ontology/obi/issues/831 on 20180511.</obo:IAO_0000117>
<obo:IAO_0000119>https://www.nanostring.com/products/mirna-assays/mirna-panels</obo:IAO_0000119>
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<!-- http://purl.obolibrary.org/obo/OBI_0002014 -->
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<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Janos Demeter</obo:IAO_0000117>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000118>DNA sequence variation detection by snp array</obo:IAO_0000118>
<obo:IAO_0000119>PMID:20393561</obo:IAO_0000119>
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<obo:IAO_0000112>pmid:20811459</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
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<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Janos Demeter</obo:IAO_0000117>
<obo:IAO_0000118>PARS</obo:IAO_0000118>
<obo:IAO_0000119>PMID:20811459</obo:IAO_0000119>
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<obo:IAO_0000112>pmid:23580730</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An RNA-seq assay that combines TL-seq with polysome fractionation</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Janos Demeter</obo:IAO_0000117>
<obo:IAO_0000118>TATL-seq</obo:IAO_0000118>
<obo:IAO_0000119>PMID:23580730</obo:IAO_0000119>
<obo:IAO_0000233>https://sourceforge.net/p/obi/obi-terms/725/</obo:IAO_0000233>
<rdfs:label>translation-associated transcript leader sequencing assay</rdfs:label>
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<obo:IAO_0000111>transcript leader sequencing assay</obo:IAO_0000111>
<obo:IAO_0000112>pmid:23580730</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An RNA-seq assay that combines enzymatic capture of m(7)G-capped mRNA 5' ends with high-throughput sequencing.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Janos Demeter</obo:IAO_0000117>
<obo:IAO_0000118>TL-seq</obo:IAO_0000118>
<obo:IAO_0000119>PMID:23580730</obo:IAO_0000119>
<obo:IAO_0000233>https://sourceforge.net/p/obi/obi-terms/725/</obo:IAO_0000233>
<rdfs:label>transcript leader sequencing assay</rdfs:label>
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<obo:IAO_0000115 xml:lang="en">A mass spectrometry assay that measures the absolute mass of the cleaved peptides derived from an unknown protein of interest. These masses are then compared to values for known protein sequences to identify the unknown protein.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Janos Demeter</obo:IAO_0000117>
<obo:IAO_0000118>PMF</obo:IAO_0000118>
<obo:IAO_0000118>protein fingerprinting</obo:IAO_0000118>
<obo:IAO_0000119>ERO:0001668</obo:IAO_0000119>
<obo:IAO_0000119>url:http://en.wikipedia.org/wiki/Peptide_mass_fingerprinting</obo:IAO_0000119>
<obo:IAO_0000233>https://sourceforge.net/p/obi/obi-terms/725/</obo:IAO_0000233>
<rdfs:label>peptide mass fingerprinting assay</rdfs:label>
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<obo:IAO_0000111>array based nucleic acid structure mapping assay</obo:IAO_0000111>
<obo:IAO_0000112>pmid:23580730</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay which aims to provide information about the in vivo organization/structure of nucleic acids using chemical or enzymatic probes using a microarray.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Janos Demeter</obo:IAO_0000117>
<obo:IAO_0000119>OBI:0000870</obo:IAO_0000119>
<obo:IAO_0000233>https://sourceforge.net/p/obi/obi-terms/725/</obo:IAO_0000233>
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<obo:IAO_0000111>micrococcal nuclease digestion followed by tiling array assay</obo:IAO_0000111>
<obo:IAO_0000112>pmid:17873876</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An array based nucleic acid structure mapping assay that identifies nucleosome positions genome wide, by detection of regions protected by nucleosomes from digestion by micrococal nuclease using tiling array assays</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Janos Demeter</obo:IAO_0000117>
<obo:IAO_0000233>https://sourceforge.net/p/obi/obi-terms/725/</obo:IAO_0000233>
<rdfs:label>micrococcal nuclease digestion followed by tiling array assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002038 -->
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<obo:IAO_0000111>ribosomal profiling by sequencing assay</obo:IAO_0000111>
<obo:IAO_0000112>Aspden et al., (August 2014). "Extensive translation of small open reading frames revealed by poly-ribo-seq." eLIFE 2014;3:e03528</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A RNA-seq assay that sequences only mRNA protected by the ribosome during translation.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000117>Venkat Malladi</obo:IAO_0000117>
<obo:IAO_0000118>Ribo-seq</obo:IAO_0000118>
<obo:IAO_0000118>Ribo-seq assay</obo:IAO_0000118>
<obo:IAO_0000118>ribosomal profiling</obo:IAO_0000118>
<obo:IAO_0000119>PMID:24468696</obo:IAO_0000119>
<rdfs:label>ribosomal profiling by sequencing assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002039 -->
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<obo:IAO_0000111>assay for transposase-accessible chromatin using sequencing</obo:IAO_0000111>
<obo:IAO_0000112>Kasinathan et al., (February 2014). "High-resolution mapping of transcription factor binding sites on natitve chromatin." Nat Methods 11(2):203-9. doi: 10.1038/nmeth.2766.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay to capture the location of open chromatin, DNA-binding proteins, individual nucleosomes and chromatin compaction at nucleotide resolution by Tn5 transposase insertion.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000117>Venkat Malladi</obo:IAO_0000117>
<obo:IAO_0000118>ATAC-seq</obo:IAO_0000118>
<obo:IAO_0000118>ATAC-seq assay</obo:IAO_0000118>
<obo:IAO_0000119>PMID:24097267</obo:IAO_0000119>
<rdfs:label>assay for transposase-accessible chromatin using sequencing</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002040 -->
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<obo:IAO_0000111>chromatin isolation by RNA purification sequencing assay</obo:IAO_0000111>
<obo:IAO_0000112>Csorba et al., (November 2014). "Antisense COOLAIR mediates the coordinated switching of chromatin states at FLC during vernalization." Proc Natl Acad Sci 111(45):16160-5. doi: 10.1073/pnas.1419030111.</obo:IAO_0000112>
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<obo:IAO_0000115 xml:lang="en">A detection of specific nucleic acids with complementary probes assay that measures regions of the genome which are bound by a specific RNA (or a by a ribonucleoprotein containing the RNA of interest) using high-throughput sequencing.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000117>Venkat Malladi</obo:IAO_0000117>
<obo:IAO_0000118>ChIRP-seq</obo:IAO_0000118>
<obo:IAO_0000118>ChIRP-seq assay</obo:IAO_0000118>
<obo:IAO_0000118>Chromatin Isolation by RNA purification</obo:IAO_0000118>
<obo:IAO_0000119>PMID:21963238</obo:IAO_0000119>
<rdfs:label>chromatin isolation by RNA purification sequencing assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002041 -->
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<obo:IAO_0000111>self-transcribing active regulatory region sequencing assay</obo:IAO_0000111>
<obo:IAO_0000112>Bohla et al., (September 2014). "A functional insulator screen identifies NURF and dREAM components to be required for enhancer-blocking." PLoS One 9(9):e107765. doi: 10.1371/journal.pone.0107765.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An RNA-seq assay that identifies the sequences that act as transcriptional enhancers in a direct, quantitative, and genome-wide manner from sheared genomic DNA.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000117>Venkat Malladi</obo:IAO_0000117>
<obo:IAO_0000118>STARR-seq</obo:IAO_0000118>
<obo:IAO_0000118>STARR-seq assay</obo:IAO_0000118>
<obo:IAO_0000118>self-transcribing active regulatory region sequencing</obo:IAO_0000118>
<obo:IAO_0000119>PMID:23328393</obo:IAO_0000119>
<rdfs:label>self-transcribing active regulatory region sequencing assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002042 -->
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<obo:IAO_0000111>carbon-copy chromosome conformation capture assay followed by sequencing assay</obo:IAO_0000111>
<obo:IAO_0000112>Fudenberg et al., (November 2014). "High order chromatin architecture shapes the landscape of chromosomal alterations in cancer." Nat Biotechol 29(12):1109-13. doi: 10.1038/nbt.2049.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A carbon-copy chromosome conformation capture assay to analyze the organization of chromosomes in an unbiased, genome-wide manner using high throughput sequening following carbon-copy chromosome conformation capture.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000117>Venkat Malladi</obo:IAO_0000117>
<obo:IAO_0000118>Carbon-copy chromosome conformation capture assay followed by sequencing</obo:IAO_0000118>
<obo:IAO_0000118>HiC</obo:IAO_0000118>
<obo:IAO_0000118>HiC assay</obo:IAO_0000118>
<obo:IAO_0000119>PMID:19815776</obo:IAO_0000119>
<rdfs:label>carbon-copy chromosome conformation capture assay followed by sequencing assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002043 -->
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<obo:IAO_0000111>individual-nucleotide resolution cross-linking and immunoprecipitation sequencing assay</obo:IAO_0000111>
<obo:IAO_0000112>Protein-RNA interactions: new genomic technologies and perspectives. Nature Reviews Genetics 13 (2): 77-83. doi:10.1038/nrg3141</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cross-linking immunoprecipitation high-throughput sequencing assay that identifies protein-RNA interactions using UV light to covalently bind proteins and RNA molecules, allowing for a very stringent purification of the linked protein-RNA complexes.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000117>Venkat Malladi</obo:IAO_0000117>
<obo:IAO_0000118>iCLIP</obo:IAO_0000118>
<obo:IAO_0000118>iCLIP assay</obo:IAO_0000118>
<obo:IAO_0000118>individual-nucleotide resolution cross-linking and immunoprecipitation</obo:IAO_0000118>
<obo:IAO_0000119>doi:10.1016/j.ymeth.2013.10.011</obo:IAO_0000119>
<rdfs:label>individual-nucleotide resolution cross-linking and immunoprecipitation sequencing assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002044 -->
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<obo:IAO_0000111>RNA Bind-n-Seq assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An RNA-seq assay that comprehensively characterizes sequence and structural specificity of RNA binding proteins (RBPs).</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000117>Venkat Malladi</obo:IAO_0000117>
<obo:IAO_0000118>RBNS</obo:IAO_0000118>
<obo:IAO_0000118>RNA Bind-n-Seq</obo:IAO_0000118>
<obo:IAO_0000118>RNBS assay</obo:IAO_0000118>
<obo:IAO_0000119>doi: 10.1016/j.molcel.2014.04.016</obo:IAO_0000119>
<rdfs:label>RNA Bind-n-Seq assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002045 -->
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<obo:IAO_0000111>polyA-site sequencing assay</obo:IAO_0000111>
<obo:IAO_0000112>Wu et al., (July 2014). "Genome-wide determination of poly(A) sites in Medicago truncatula: evolutionary conservation of alternative poly(A) site choice. BMC Genomics. 2014 Jul 21;15:615. doi: 10.1186/1471-2164-15-615.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A RNA-seq assay that quantitatively profiles RNA polyadenylation at the transcriptome level.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000117>Venkat Malladi</obo:IAO_0000117>
<obo:IAO_0000118>PAS-seq</obo:IAO_0000118>
<obo:IAO_0000118>PAS-seq assay</obo:IAO_0000118>
<obo:IAO_0000118>Poly(A)-site sequencing</obo:IAO_0000118>
<obo:IAO_0000118>poly(A)-site sequencing assay</obo:IAO_0000118>
<obo:IAO_0000119>doi: 10.1261/rna.2581711</obo:IAO_0000119>
<rdfs:label>polyA-site sequencing assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002046 -->
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</owl:Restriction>
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<obo:IAO_0000111>surface plasmon resonance sensor chip</obo:IAO_0000111>
<obo:IAO_0000112>ProteOn GLC Sensor Chip #176-5011</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A device that is used as a binding surface for ligand during a surface plasmon resonance assay, consisting of a glass plate to which a metal film is attached</obo:IAO_0000115>
<obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
<obo:IAO_0000118>SPR sensor chip</obo:IAO_0000118>
<obo:IAO_0000118>biosensor chip</obo:IAO_0000118>
<obo:IAO_0000118>sensor chip</obo:IAO_0000118>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>surface plasmon resonance sensor chip</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002047 -->
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<obo:IAO_0000111>enzyme-linked antibody</obo:IAO_0000111>
<obo:IAO_0000112>Goat anti-Mouse IgG-HRP (horse radish peroxidase) is an antibody linked to the enzyme horseradish peroxidase (HRP) that catalyzes the conversion of chromogenic substrates into colored products producing light when acting on chemiluminescent substrates (ECL).</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A processed material that is comprised of an antibody that is covalently linked to an enzyme through bioconjugation. The enzyme can be used as a detection method when the enzyme's reaction produces a detectable signal, for example a color change when the substrate is added.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters, Randi Vita, James A. Overton</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>enzyme-linked antibody</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002048 -->
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<obo:IAO_0000111>Illumina HiSeq 3000</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A DNA sequencer manufactured by Illumina corporation, with a single flow cell and a throughput of more than 200 Gb per day.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Sagar Jain, Richard Scheuermann</obo:IAO_0000117>
<obo:IAO_0000118>HiSeq 3000</obo:IAO_0000118>
<obo:IAO_0000119>http://www.illumina.com/systems/hiseq-3000-4000.html</obo:IAO_0000119>
<rdfs:label>Illumina HiSeq 3000</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002049 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002049">
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<obo:IAO_0000111>Illumina HiSeq 4000</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A DNA sequencer manufactured by Illumina corporation, with two flow cell and a throughput of more than 400 Gb per day.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Sagar Jain, Richard Scheuermann</obo:IAO_0000117>
<obo:IAO_0000118>HiSeq 4000</obo:IAO_0000118>
<obo:IAO_0000119>http://www.illumina.com/systems/hiseq-3000-4000.html</obo:IAO_0000119>
<rdfs:label>Illumina HiSeq 4000</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002050 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001145"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002075"/>
<obo:IAO_0000111>3D molecular structure determination assay of a MHC:ligand complex</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A 3D structure determination of bound molecular complex assay that characterizes the 3-dimensional structure of a MHC:ligand complex.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>3D structure|any method</obo:OBI_9991118>
<rdfs:label>3D molecular structure determination assay of a MHC:ligand complex</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002051 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001186"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003465"/>
<obo:IAO_0000111>in vivo assay measuring B cell epitope specific protection from infectious challenge based on pathogen burden</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An in vivo assay measuring B cell epitope specific protection from pathogen challenge using pathogen burden.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>pathogen burden after challenge|in vivo assay</obo:OBI_9991118>
<rdfs:label>in vivo assay measuring B cell epitope specific protection from infectious challenge based on pathogen burden</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002052 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002052">
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</owl:Restriction>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003466"/>
<obo:IAO_0000111>in vivo assay measuring B cell epitope specific protection after tumor burden challenge</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An in vivo assay measuring B cell epitope specific protection from tumor challenge using tumor burden.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>tumor burden after challenge|in vivo assay</obo:OBI_9991118>
<rdfs:label>in vivo assay measuring B cell epitope specific protection after tumor burden challenge</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002053 -->
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0003141"/>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001703"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001985"/>
<obo:IAO_0000111>microarray assay measuring binding of a B cell epitope:antibody complex</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A microarray assay that detects the binding of an antigen with an antibody.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>qualitative binding|microarray</obo:OBI_9991118>
<rdfs:label>microarray assay measuring binding of a B cell epitope:antibody complex</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002054 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002054">
<owl:equivalentClass>
<owl:Class>
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</owl:intersectionOf>
</owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000039"/>
<owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/UO_0000065"/>
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</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001708"/>
<obo:IAO_0000111>NMR assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A B cell epitope equilibrium dissociation constant (KD) determination assay that uses a nuclear magnetic resonance assay.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>dissociation constant KD|nuclear magnetic resonance (NMR)|nM</obo:OBI_9991118>
<rdfs:label>NMR assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002055 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003128"/>
<obo:IAO_0000111>assay measuring biological activity resulting from T cell epitope:MHC:TCR binding</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A T cell epitope recognition assay that measures the immune response process resulting from the binding of a T cell receptor to epitope or the recongition of the epitope.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>biological activity|any method</obo:OBI_9991118>
<rdfs:label>assay measuring biological activity resulting from T cell epitope:MHC:TCR binding</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002056 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110129"/>
<obo:IAO_0000111>assay measuring epitope specific chemokine (C-C motif) ligand 17 production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A T cell epitope specific cytokine production assay that detects production of chemokine (C-C motif) ligand 17 production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>CCL17/TARC release|biological activity</obo:OBI_9991118>
<rdfs:label>assay measuring epitope specific chemokine (C-C motif) ligand 17 production by T cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002057 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002057">
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110129"/>
<obo:IAO_0000111>assay measuring epitope specific macrophage migration inhibitory factor (MIF) production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A T cell epitope specific cytokine production assay that detects macrophage migration inhibitory factor (MIF) production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>MIF release|biological activity</obo:OBI_9991118>
<rdfs:label>assay measuring epitope specific macrophage migration inhibitory factor (MIF) production by T cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002058 -->
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<obo:IAO_0000115 xml:lang="en">An in vitro cell killing assay that measures the killing of antigen presenting cells (APC) by T cells whose TCR recognizes an epitope presented by the APC.</obo:IAO_0000115>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001497"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600031"/>
<obo:IAO_0000111>ELISPOT assay measuring epitope specific perforin release by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An enzyme-linked immunospot assay that detects epitope specific perforin release by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>perforin release|ELISPOT</obo:OBI_9991118>
<rdfs:label>ELISPOT assay measuring epitope specific perforin release by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002070 -->
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0042098"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0003385"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_33208"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000086"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0001421"/>
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</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001484"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110131"/>
<obo:IAO_0000111>in vivo assay measuring epitope specific proliferation of T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A T cell epitope specific proliferation assay that is performed in vivo.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>proliferation|in vivo assay</obo:OBI_9991118>
<rdfs:label>in vivo assay measuring epitope specific proliferation of T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002071 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002071">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Class>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0042098"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0003385"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001876"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110131"/>
<obo:IAO_0000111>in vitro assay measuring epitope specific proliferation of T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A T cell epitope specific proliferation assay that is performed on cells in vitro.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>proliferation|in vitro assay</obo:OBI_9991118>
<rdfs:label>in vitro assay measuring epitope specific proliferation of T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002072 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002072">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0003141"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001503"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110126"/>
<obo:IAO_0000111>assay measuring qualitative binding of a MHC:ligand complex</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that detects the binding of a MHC molecule with a ligand, and produces a qualitative measurement of the binding as an output.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>qualitative binding|binding assay</obo:OBI_9991118>
<rdfs:label>assay measuring qualitative binding of a MHC:ligand complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002073 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002073">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001184"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0003385"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_33208"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000086"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0001421"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001184"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001484"/>
<obo:IAO_0000111>in vivo assay measuring T cell epitope specific protection from challenge</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An efficacy of T cell epitope intervention experiment that uses a epitope protection experiment.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>protection from challenge|in vivo assay</obo:OBI_9991118>
<rdfs:label>in vivo assay measuring T cell epitope specific protection from challenge</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002074 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002074">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002055"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0003385"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001876"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>assay measuring T cell epitope specific suppression in vitro</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">T cell epitope dependent biological activity assay that detects suppression of an in vitro response.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, James Overton, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>suppression|in vitro assay</obo:OBI_9991118>
<rdfs:label>assay measuring T cell epitope specific suppression in vitro</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002075 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002075">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001503"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003121"/>
</owl:unionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110128"/>
<obo:IAO_0000111>MHC ligand assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An immune epitope assay that characterizes the structrue of a MHC-ligand complex, or detects the processing and presentation of a ligand by an antigen presenting cell, or the binding of a ligand to an MHC molecule.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>MHC ligand assay|any method</obo:OBI_9991118>
<rdfs:label>MHC ligand assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002076 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002076">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002351"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100051"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000111 xml:lang="en">collection of specimens</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Blood cells collected from multiple donors over the course of a study.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A material entity that has two or more specimens as its parts.</obo:IAO_0000115>
<obo:IAO_0000116>Details see tracker: https://sourceforge.net/p/obi/obi-terms/778/</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>OBIB, OBI</obo:IAO_0000119>
<dc:source>Biobank</dc:source>
<rdfs:label xml:lang="en">collection of specimens</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002077 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002077">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002076"/>
<obo:IAO_0000111 xml:lang="en">specimens derived from shared ancestor</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Aliquoting one specimen to multiple tubes and the collection of the aliquoted specimens are a specimen family. Slicing a tissue specimen into multiple sections for microscopy.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A collection of specimens derived from one common specimen via one or more material processing process(es).</obo:IAO_0000115>
<obo:IAO_0000116>Details see tracker: https://sourceforge.net/p/obi/obi-terms/778/</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">specimen family</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">Duke Biobank, OBIB, OBI</obo:IAO_0000119>
<dc:source>Biobank</dc:source>
<rdfs:label xml:lang="en">specimens derived from shared ancestor</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002078 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002078">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
<obo:IAO_0000111 xml:lang="en">specimen set collection process</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Collection of both blood and urine specimens in one clinical visit; Taking out liver and brain specimens during an autopsy.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A specimen collection process that generates multiple specimens from one source (e.g. one organism) during a time period which for the purpose of the study can be considered to be taken at the same sampling time.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBIB, OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">specimen set collection process</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002079 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002079">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002076"/>
<obo:IAO_0000111 xml:lang="en">specimens collected in one encounter</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Both blood and urine specimens collected in one clinical visit; liver and brain specimens taken during an autopsy.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A collection of specimens that is collected from one source (e.g. one organism) during a time period which for the purpose of the study can be considered to be taken at the same sampling time.</obo:IAO_0000115>
<obo:IAO_0000116>Details see tracker: https://sourceforge.net/p/obi/obi-terms/778/</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">specimen set</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">OBIB, OBI</obo:IAO_0000119>
<dc:source>Biobank</dc:source>
<rdfs:label xml:lang="en">specimens collected in one encounter</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002080 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002080">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002079"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002079"/>
<obo:IAO_0000111 xml:lang="en">human specimen set</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen set that is collected from one person during a time period which for the purpose of the study can be considered to be taken at the same sampling time.</obo:IAO_0000115>
<obo:IAO_0000116>Details see tracker: https://sourceforge.net/p/obi/obi-terms/778/</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Person: Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">Duke Biobank, OBIB, OBI</obo:IAO_0000119>
<dc:source>Biobank</dc:source>
<rdfs:label xml:lang="en">human specimen set</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002081 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002081">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002076"/>
<obo:IAO_0000111 xml:lang="en">specimens collected longitudinally</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A collection of specimens that was derived from the same source material entity at different time points in order to observe changes in that entity.</obo:IAO_0000115>
<obo:IAO_0000116>Details see tracker: https://sourceforge.net/p/obi/obi-terms/778/</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Person: Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">Bjoern Peters, OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">specimens collected longitudinally</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002082 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002082">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>reporter gene assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">An assay that detects expression of a reporter gene that was inserted under the control of a regulatory sequence of interest.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Paul D. Thomas</obo:IAO_0000117>
<obo:IAO_0000118>reporter gene detection assay</obo:IAO_0000118>
<obo:IAO_0000119>Paul D. Thomas, Yang Chai; FaceBase</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/781</obo:IAO_0000233>
<rdfs:label>reporter gene assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002083 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002083">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002082"/>
<obo:IAO_0000111>enhancer activity detection by reporter gene assay</obo:IAO_0000111>
<obo:IAO_0000112>PMID 19268701: "we experimentally concatenated up to four enhancers from different genes and used a transgenic mouse assay to compare the in vivo activity of these compound elements with that of the single modules"</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A reporter gene assay that detects expression of a reporter gene that was inserted under the control of an enhancer of interest.</obo:IAO_0000115>
<obo:IAO_0000117>Paul D. Thomas</obo:IAO_0000117>
<obo:IAO_0000117>Yang Chai</obo:IAO_0000117>
<obo:IAO_0000118>enhancer reporter gene assay</obo:IAO_0000118>
<obo:IAO_0000119>FaceBase</obo:IAO_0000119>
<obo:IAO_0000119>PMID 24614317</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/781</obo:IAO_0000233>
<rdfs:label>enhancer activity detection by reporter gene assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002084 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002084">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000716"/>
<obo:IAO_0000111>transcription cofactor activity region identification by ChIP-Seq assay</obo:IAO_0000111>
<obo:IAO_0000112>PMID 19212405: "we present the results of chromatin immunoprecipitation with the enhancer-associated protein p300 followed by massively parallel sequencing, and map several thousand in vivo binding sites of p300 in mouse embryonic forebrain, midbrain and limb tissue"</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A ChIP-seq assay that identifies regions of chromatin bound to a chromatin modifying protein, e.g. a histone acetyltransferase.</obo:IAO_0000115>
<obo:IAO_0000117>Paul D. Thomas</obo:IAO_0000117>
<obo:IAO_0000117>Yang Chai</obo:IAO_0000117>
<obo:IAO_0000118>chromatin modifier binding site identification by ChIP-Seq assay</obo:IAO_0000118>
<obo:IAO_0000119>PMID:19212405</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/782</obo:IAO_0000233>
<rdfs:label>transcription cofactor activity region identification by ChIP-Seq assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002085 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002085">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001686"/>
<obo:IAO_0000111>transcript expression location detection by hybridization chain reaction assay</obo:IAO_0000111>
<obo:IAO_0000112>PMID 25977364: "Multiplexed imaging of mRNA expression using fluorescent hybridization chain reaction (HCR) quantitatively confirmed the expression profiles of lead cells"</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">An in situ hybridization assay in which the location (e.g. anatomical/tissue) of a transcript is detected by a multiplexed fluorescent in situ hybridization, based on orthogonal amplification with hybridization chain reactions (HCR). RNA probes complementary to mRNA targets trigger chain reactions in which fluorophore-labeled RNA hairpins self-assemble into tethered fluorescent amplification polymers.</obo:IAO_0000115>
<obo:IAO_0000117>Paul D. Thomas</obo:IAO_0000117>
<obo:IAO_0000117>Yang Chai</obo:IAO_0000117>
<obo:IAO_0000118>transcript expression location detection by fluorescent HCR.</obo:IAO_0000118>
<obo:IAO_0000119>PMID:21037591</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/783</obo:IAO_0000233>
<rdfs:label>transcript expression location detection by hybridization chain reaction assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002086 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002086">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000748"/>
<obo:IAO_0000111>Tet-assisted bisulfite sequencing assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A bisulfite sequencing assay that identifies genomic methylation patterns by using a bisulfite based protocol with the Tet enzyme to differentiate 5-hydroxylmethylcytosine (5hmC) from 5-methylcytosine (5mC) through a step-wise oxidative demethylation of 5mC, converting it to 5-carboxylcytosine (5caC) while keeping 5hmC protected.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jason Hilton</obo:IAO_0000117>
<obo:IAO_0000117>OBI</obo:IAO_0000117>
<obo:IAO_0000118>TAB-seq</obo:IAO_0000118>
<obo:IAO_0000118>Tet-assisted bisulfite sequencing</obo:IAO_0000118>
<obo:IAO_0000119>PMID:23196972</obo:IAO_0000119>
<obo:IAO_0000233>http://sourceforge.net/p/obi/obi-terms/789/</obo:IAO_0000233>
<rdfs:label>Tet-assisted bisulfite sequencing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002087 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002087">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000370"/>
<obo:IAO_0000111 xml:lang="en">containing a specimen function</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A contain function that involves physical contact with a specimen. This function is typically performed in such a way that the specimen is usable for an investigation or assay.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">For details see tracker item: http://sourceforge.net/p/obi/obi-terms/792/</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Duke Biobank, OBIB</obo:IAO_0000119>
<dc:source xml:lang="en">Biobank</dc:source>
<rdfs:label xml:lang="en">containing a specimen function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002088 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002088">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000967"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002087"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000967"/>
<obo:IAO_0000111>specimen container</obo:IAO_0000111>
<obo:IAO_0000112>COPAN eSwab, CPT vacutainer, PAXgene Blood DNA tube</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A container with the function of containing a specimen.</obo:IAO_0000115>
<obo:IAO_0000116>For details see tracker item: http://sourceforge.net/p/obi/obi-terms/792/</obo:IAO_0000116>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Duke Biobank, OBIB</obo:IAO_0000119>
<rdfs:label>specimen container</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002089 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002089">
<owl:equivalentClass>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000401"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000967"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001034"/>
<obo:IAO_0000111>physical store</obo:IAO_0000111>
<obo:IAO_0000112>a freezer. a humidity controlled box.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A container with an environmental control function.</obo:IAO_0000115>
<obo:IAO_0000116>For details see tracker item: http://sourceforge.net/p/obi/obi-terms/793/</obo:IAO_0000116>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Duke Biobank, OBIB</obo:IAO_0000119>
<rdfs:label>physical store</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002090 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002090">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000552"/>
<obo:IAO_0000111>rapid amplification of cDNA ends</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A reverse transcribed polymerase chain reaction that is used to amplify a mRNA sequence between a defined internal site and the 5' or 3' end of the mRNA.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">For details see tracker item: https://sourceforge.net/p/obi/obi-terms/790/</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Jason Hilton, Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000118>RACE</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">http://www.clontech.com/US/Products/cDNA_Synthesis_and_Library_Construction/RACE_Rapid_Amplification_of_cDNA_Ends/5_Prime_RACE_and_3_Prime_RACE</obo:IAO_0000119>
<dc:source xml:lang="en">ENCODE</dc:source>
<rdfs:label xml:lang="en">rapid amplification of cDNA ends</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002091 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002091">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002090"/>
<obo:IAO_0000111 xml:lang="en">5' rapid amplification of cDNA ends</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A rapid amplication of cDNA ends to amplify a mRNA sequence between a defined internal site and the 5' end of the mRNA.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">For details see tracker item: https://sourceforge.net/p/obi/obi-terms/790/</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Jason Hilton, Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">5' RACE</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">https://www.thermofisher.com/us/en/home/references/protocols/nucleic-acid-amplification-and-expression-profiling/cdna-protocol/5-race-system-for-rapid-amplification-of-cdna-ends.html</obo:IAO_0000119>
<dc:source xml:lang="en">ENCODE</dc:source>
<rdfs:label xml:lang="en">5' rapid amplification of cDNA ends</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002092 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002092">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002090"/>
<obo:IAO_0000111 xml:lang="en">3' rapid amplification of cDNA ends</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A rapid amplication of cDNA ends to amplify a mRNA sequence between a defined internal site and the 3' end of the mRNA.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">For details see tracker item: https://sourceforge.net/p/obi/obi-terms/790/</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Jason Hilton, Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">3' RACE</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">https://www.thermofisher.com/us/en/home/references/protocols/nucleic-acid-amplification-and-expression-profiling/cdna-protocol/3-race-system-for-rapid-amplification-of-cdna-ends.html</obo:IAO_0000119>
<dc:source xml:lang="en">ENCODE</dc:source>
<rdfs:label xml:lang="en">3' rapid amplification of cDNA ends</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002093 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002093">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002091"/>
<obo:IAO_0000111 xml:lang="en">5' RNA ligase mediated rapid amplification of cDNA ends</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A 5' rapid amplification pf cDNA ends that uses RNA ligase to add an RNA adapter oligonucleotide to intact 5' mRNA ends, allowing the amplification of cDNA only from full-length, capped mRNA.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">For details see tracker item: https://sourceforge.net/p/obi/obi-terms/790/</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Jason Hilton, Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">5' RLM RACE</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">https://tools.thermofisher.com/content/sfs/manuals/cms_056070.pdf</obo:IAO_0000119>
<dc:source xml:lang="en">ENCODE</dc:source>
<rdfs:label xml:lang="en">5' RNA ligase mediated rapid amplification of cDNA ends</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002094 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002094">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000748"/>
<obo:IAO_0000111>MethylC-Capture sequencing assay</obo:IAO_0000111>
<obo:IAO_0000112>MethylC-Capture Sequencing approach was introduced as a cost-effective and customizable alternative method for large-scale interrogation of functionally-active methylomes while simultaneously providing genetic variation information in a proof-of-concept epigenome-wide association study of 72 obese individuals, identifying novel disease-associated variants.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A bisulfite sequencing assay in which a whole-genome sequencing library is prepared, bisulfite converted and amplified, followed by a capture enriching for targeted bisulfite-converted DNA fragments that are are subsequently identified by DNA sequencing.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>David Bujold</obo:IAO_0000117>
<obo:IAO_0000118>Capture Methylome</obo:IAO_0000118>
<obo:IAO_0000118>MCC-Seq</obo:IAO_0000118>
<obo:IAO_0000118>MethylC-Capture Sequencing</obo:IAO_0000118>
<obo:IAO_0000119>PMID:26021296</obo:IAO_0000119>
<rdfs:label>MethylC-Capture sequencing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002095 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002095">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000094"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100051"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002077"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">specimen family creation</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Aliquoting one specimen to multiple tubes, slicing a tissue specimen into multiple sections, processing blood into buffy coat, red cells, and serum.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A material processing that has as its input a specimen and as its output a collection of specimens.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">For details see tracker: https://sourceforge.net/p/obi/obi-terms/778/</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Mathias Brochhausen, Chris Stoeckert, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI, OBIB</obo:IAO_0000119>
<dc:source xml:lang="en">Biobank</dc:source>
<rdfs:label xml:lang="en">specimen family creation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002096 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002096">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002106"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0042098"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0003385"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001876"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002071"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002106"/>
<obo:IAO_0000111>carboxyfluorescein succinimidyl ester staining assay measuring epitope specific proliferation of T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A CFSE assay that detects T cell epitope specific proliferation in vitro.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>proliferation|CFSE</obo:OBI_9991118>
<rdfs:label>carboxyfluorescein succinimidyl ester staining assay measuring epitope specific proliferation of T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002097 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002097">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001536"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000039"/>
<owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/UO_0000065"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002059"/>
<obo:IAO_0000111>assay measuring the dissociation constant [KD] of a T cell epitope:MHC:TCR complex</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A T cell epitope binding constant determination assay that measures the dissociation constant KD.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
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<obo:IAO_0000111 xml:lang="en">digital object identifier</obo:IAO_0000111>
<obo:IAO_0000112>The doi symbol: "10.1109/5.771073" resolves to ieee website: http://ieeexplore.ieee.org/xpl/articleDetails.jsp?reload=true&arnumber=771073</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A centrally registered identifier symbol used to uniquely identify objects given by International DOI Foundation. The DOI system is particularly used for electronic documents such as journal articles.</obo:IAO_0000115>
<obo:IAO_0000116>Discussed on Aug 22, 2016 OBI dev call. Details see tracker:
https://sourceforge.net/p/obi/obi-terms/818/</obo:IAO_0000116>
<obo:IAO_0000117>OBI developers</obo:IAO_0000117>
<obo:IAO_0000118>DOI</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Digital_object_identifier
https://www.doi.org/</obo:IAO_0000119>
<rdfs:label xml:lang="en">digital object identifier</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002111 -->
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<obo:IAO_0000111>enhanced cross-linking immunoprecipitation high-throughput sequencing assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An iCLIP assay that is enhanced to robustly identify protein-RNA interactions with high efficiency through improvements in library preparation of RNA fragments.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jason Hilton</obo:IAO_0000117>
<obo:IAO_0000118>eCLIP</obo:IAO_0000118>
<obo:IAO_0000119>PMID:27018577</obo:IAO_0000119>
<rdfs:label>enhanced cross-linking immunoprecipitation high-throughput sequencing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002112 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002112">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001271"/>
<obo:IAO_0000111>small RNA sequencing assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An RNA-seq assay which is targeting small RNA (< 200 bp) sequences such as, but not exclusive to, miRNAs using, for example, small RNA library preparation kits.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jason Hilton</obo:IAO_0000117>
<obo:IAO_0000117>Mark A. Miller</obo:IAO_0000117>
<obo:IAO_0000118>short RNA-seq</obo:IAO_0000118>
<obo:IAO_0000118>small RNA-seq</obo:IAO_0000118>
<obo:IAO_0000119>url:http://science.sciencemag.org/content/316/5830/1484.full</obo:IAO_0000119>
<obo:IAO_0000119>url:http://www.illumina.com/techniques/sequencing/rna-sequencing/small-rna-seq.html</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/859</obo:IAO_0000233>
<rdfs:label>small RNA sequencing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002113 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002113">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001271"/>
<obo:IAO_0000111>bromouridine labeling and sequencing assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An RNA-seq assay to identify spans of nascent transcription in the genome through isolation of recent bromouridine (Bru) labelled RNAs.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jason Hilton</obo:IAO_0000117>
<obo:IAO_0000118>Bru-seq</obo:IAO_0000118>
<obo:IAO_0000119>PMC:4009065</obo:IAO_0000119>
<rdfs:label>bromouridine labeling and sequencing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002114 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002114">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001271"/>
<obo:IAO_0000111>bromouridine pulse-chase and sequencing assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An RNA-seq assay to identify RNA populations of specific ages through isolation of RNAs first labelled with bromouridine (Bru) followed by chasing in uridine for different periods of time.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jason Hilton</obo:IAO_0000117>
<obo:IAO_0000118>BruChase-seq</obo:IAO_0000118>
<obo:IAO_0000119>PMC:4009065</obo:IAO_0000119>
<rdfs:label>bromouridine pulse-chase and sequencing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002115 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002115">
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002743"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33321"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000470"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003368"/>
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<obo:IAO_0000111>cytometry time of flight assay</obo:IAO_0000111>
<obo:IAO_0000112>Whole human blood samples were incubated with lipopolysaccharide (LPS) to examine dose-dependent signaling responses within the toll-like receptor 4 (TLR4) pathway. After LPS stimulation, rare earth metal tagged antibodies against phenotypic markers were used to stain the blood sample (Nd143-CD45RA, Nd145-CD4, Er170-CD3, Sm152-TCR__, Pr141-CD7, Nd146-CD8, Nd142-CD19). A Fluidigm CyTOF version 1 instrument equipped with CyTOF software version 5.1.648 was used to measure and analyze the levels of antibody staining reflective of the level of expression of those surface receptors.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay in which the presence of molecules of interest on or in cells is indicated by binding of antibodies labeled with rare earth element tags which are detected by time-of-flight mass spectrometry.</obo:IAO_0000115>
<obo:IAO_0000117>ImmPort</obo:IAO_0000117>
<obo:IAO_0000118>CyTOF</obo:IAO_0000118>
<obo:IAO_0000118>mass cytometry assay</obo:IAO_0000118>
<obo:IAO_0000119>PMID:26190063</obo:IAO_0000119>
<rdfs:label>cytometry time of flight assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002116 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002116">
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001057"/>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001057"/>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001630"/>
<obo:IAO_0000111>high performance liquid chromotography assay</obo:IAO_0000111>
<obo:IAO_0000112>On-line coupled immunoaffinity chromatography-reversed-phase high-performance liquid chromatography (IAC-HPLC) with detection by quadrupole ion trap mass spectrometry using a particle beam interface has been developed for the determination of the steroids, dexamethasone and flumethasone. HEMA (polyhydroxyethylmethacrylate) was evaluated as a support material for the anti-dexamethasone antibodies used in IAC. Antibody cross-reactivity and non-specific binding have been investigated for the HEMA bound anti-dexamethasone IAC column. The on-line IAC-HPLC-MS determination of dexamethasone and flumethasone in post-administration equine urine samples showed precisions (R.S.D.) of 8.0 and 7.1%, respectively, with limits of detection in the range 3-4 ng/ml.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analytical chromatography assay that utilizes a high performance liquid chromatography instrument for separation of compounts in a solution.</obo:IAO_0000115>
<obo:IAO_0000117>ImmPort</obo:IAO_0000117>
<obo:IAO_0000118>HPLC</obo:IAO_0000118>
<obo:IAO_0000119>PMID:9491555</obo:IAO_0000119>
<rdfs:label>high performance liquid chromotography assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002117 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002117">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000626"/>
<obo:IAO_0000111>whole genome sequencing assay</obo:IAO_0000111>
<obo:IAO_0000112>WGS permits comprehensive sequencing of introns and exons, whereas whole exome sequencing (WES) allows deeper sequencing of exonic regions at a lower cost. Due to the large number of genetic variants found in each genome, it is necessary to use filtering approaches to distinguish deleterious from benign variants. WES has been used successfully to identify novel genetic causes of primary immunodeficiency. Complex structural variations and non-Mendelian disorders remain challenges for WGS.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A DNA sequencing assay that intends to provide information about the sequence of an entire genome of an organism.</obo:IAO_0000115>
<obo:IAO_0000116>Genotyping assays should ideally identify which part of the genome the information is about. We do not currently have a good way to do this. That information should be added later.</obo:IAO_0000116>
<obo:IAO_0000117>ImmPort</obo:IAO_0000117>
<obo:IAO_0000118>WGS</obo:IAO_0000118>
<obo:IAO_0000119>PMID:23095910</obo:IAO_0000119>
<obo:IAO_0000119>PMID:25827230</obo:IAO_0000119>
<rdfs:label>whole genome sequencing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002118 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002118">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000626"/>
<obo:IAO_0000111>exome sequencing assay</obo:IAO_0000111>
<obo:IAO_0000112>DNA was extracted from the Ficoll pellet of blood taken from congenital asplenia patients. Unamplified, high-molecular weight, RNase-treated genomic DNA (4_6 _g) was used for whole exome sequencing (WES) with the use of Agilent 71 Mb (V4 + UTR) singlesample capture and an Illumina HiSeq 2000. Sequencing was carried out so as to obtain 30_ coverage from 2 _ 100-bp paired-end reads. We used the Annovar tool (25) to annotate the resulting highquality (HQ) variants. In the regions targeted by WES capture (81.5% of the consensus coding genome), the mean numbers of single-nucleotide variants (SNVs) and small insertions/deletions (indels) detected per sample were 84,192 and13,325, respectively. After filtering, a mean of 74,398 (95.3%) high-quality (HQ) SNVs and 9,033 (70.6%) HQ indels were called. A mean of 105 coding HQ SNVs and 32 indels was identified.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A DNA sequencing assay that intends to provide information about the sequence of the protein coding components of a genome (exons).</obo:IAO_0000115>
<obo:IAO_0000117>ImmPort</obo:IAO_0000117>
<obo:IAO_0000118>WES</obo:IAO_0000118>
<obo:IAO_0000119>PMID:25827230</obo:IAO_0000119>
<rdfs:label>exome sequencing assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002119 -->
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<owl:equivalentClass>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000185"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400169"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000185"/>
<obo:IAO_0000111>microscopy assay</obo:IAO_0000111>
<obo:IAO_0000112>Lung, liver, and spleen tissue samples were collected from female BALB/c mice and fixed in 100% formalin solution, embedded in paraffin, sectioned, and stained with hematoxylin and eosin. The stained samples were examined for signs of pathological changes under light microscopy.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An imaging assay that utilizes a microscope to magnify features of the visualized material of interest that are not visible to naked eye.</obo:IAO_0000115>
<obo:IAO_0000117>ImmPort</obo:IAO_0000117>
<obo:IAO_0000119>PMID:21685355</obo:IAO_0000119>
<rdfs:label>microscopy assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002120 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001977"/>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000086"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002744"/>
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<obo:IAO_0000111>mixed lymphocyte reaction assay</obo:IAO_0000111>
<obo:IAO_0000112>T cells were separated from PBL of laboratory volunteers and used as responder cells (R). Mitomycin C-treated allogeneic mAPC enriched populations were used as stimulators (S), incubated for 5 days, pulsed with 3H-thymidine (3H-TdR) for 16 hours, harvested, and radioactivity counted using a beta scintillation counter to measure proliferation of the 3H-thymidine labeled cells.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay where lymphocytes from two individuals are co-cultured with the lymphocytes from one of the allogeneic individuals (Responders) being labeled (with 3H Thymidine or BrdU) and the proliferation of the labeled cells is measured, which is thought to reflect recognition of histocompatibility antigens on the unlabeled cells (stimulators).</obo:IAO_0000115>
<obo:IAO_0000117>ImmPort</obo:IAO_0000117>
<obo:IAO_0000118>MLR</obo:IAO_0000118>
<obo:IAO_0000119>PMID:14969764</obo:IAO_0000119>
<rdfs:label>mixed lymphocyte reaction assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002121 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000435"/>
<obo:IAO_0000111>killer cell immunoglobulin-like receptor typing assay</obo:IAO_0000111>
<obo:IAO_0000112>DNA was isolated from PBMCs from healthy donors.The single-nucleotide polymorphism (SNP) assay was performed on an HT7900 Sequence Detection System (Applied Biosystems) following the allelic discrimination assay protocol provided by the manufacturer. Primers for the assay were designed in such a way that they amplified all the alleles of a particular HLA type (HLA-B or HLA-C) as well as the amplicon containing the polymorphic region of interest. Two probes were designed with a single mismatch between them. Each probe bound only one group of alleles and was labeled with either 6FAM or VIC fluorescent dye at its 5_ end. The 3_ end of the probes contained a quencher. For KIR2DL1 functional allele typing, the probe was designed based on a single-nucleotide mismatch at amino acid position 245 in the mature protein. A universal primer was designed that could specifically amplify all the alleles of KIR2DL1.The SNP assay was run on the HT7900 using the same protocol as described for KIR ligand typing. Results showed that 20 individuals had only arginine at amino acid position 245 of KIR2DL1, 5 were heterozygous for arginine and cysteine, and 1 had only cysteine in that position.Thus, this approach was useful not only for the identification of functional groups of KIR alleles, but also for determining the presence of the KIR gene itself.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A genotyping assay in which the alleles of genes encoding for killer cell immunoglobulin-like receptors are determined.</obo:IAO_0000115>
<obo:IAO_0000116>Genotyping assays should ideally identify which part of the genome the information is about. We do not currently have a good way to do this. That information should be added later.</obo:IAO_0000116>
<obo:IAO_0000117>ImmPort</obo:IAO_0000117>
<obo:IAO_0000118>KIR typing</obo:IAO_0000118>
<obo:IAO_0000119>PMID:21239231</obo:IAO_0000119>
<rdfs:label>killer cell immunoglobulin-like receptor typing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002122 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002122">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000435"/>
<obo:IAO_0000111>major histocompatibility typing assay</obo:IAO_0000111>
<obo:IAO_0000112>Blood samples from Holstein-Friesian heifer calves were used to isolate white blood cell (WBC) pellets, from which total RNA was extracted using Tri-reagent and cDNA generated using a Reverse Transcription Kit, both_ according to the manufacturers? instructions. An alignment of sequences of known bovine MHCI gene cDNAs, as presented in the IPD-MHC database (May 2014), was used to design a series of 3_ (for) and 5_ (rev) pan-MHCI primers. cDNA from individual animals was subject to PCR amplification in two separate reactions using either the For1/Rev2 or the For3/Rev1 primer pairs. For each sample primers using a unique combination of MID tags were used to allow subsequent de-multiplexing of the sequence data. PCRs were conducted using the Phusion High-Fidelity PCR kit. Following amplification, 5?_l of PCR products from each sample were pooled, purified using Agencourt AMPure XP Beads and run on a 1.5?% agarose gel. Bands of the appropriate size_ were extracted and purified using the Qiagen Gel extraction kit. Libraries were submitted to Edinburgh Genomics where after standard quality control procedures they underwent 300 base paired-end sequencing on an Illumina MiSeq v3. Data were separated into reads generated from For1Rev2 and For3Rev1 primer pairs, generating separate datasets for up to 192 samples. Within each sample, reads were clustered into unique variants which were subsequently compared using BLAST against a database of the previously identified bovine MHCI sequences. This process identified >140 novel classical MHCI genes and defined 62 novel MHCI haplotypes, dramatically expanding the known bovine MHCI repertoire.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A genotyping assay in which the alleles of genes encoding for major histocompatibility complex molecules are determined.</obo:IAO_0000115>
<obo:IAO_0000116>Genotyping assays should ideally identify which part of the genome the information is about. We do not currently have a good way to do this. That information should be added later.</obo:IAO_0000116>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000118>MHC typing, HLA typing</obo:IAO_0000118>
<obo:IAO_0000119>PMC:2628004</obo:IAO_0000119>
<obo:IAO_0000119>PMID:27516207</obo:IAO_0000119>
<rdfs:label>major histocompatibility typing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002123 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0302887"/>
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<obo:IAO_0000111 xml:lang="en">IHC slide staining</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A staining using labeled antibodies, i.e. the analytical part of immunohistochemistry. The staining is applied to fixed specimens on slides to identify biomarkers in tissues.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Chris Stoeckert, Ned Haubein</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">http://www.agilent.com/cs/library/technicaloverviews/public/08002_ihc_staining_methods.pdf</obo:IAO_0000119>
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<obo:IAO_0000115 xml:lang="en">A fixed tissue slide specimen that is the output of H&E slide staining.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Ned Haubein</obo:IAO_0000117>
<obo:IAO_0000119>OBIB, OBI</obo:IAO_0000119>
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<obo:IAO_0000115 xml:lang="en">A fixed tissue slide specimen that is the output of immunohistochemistry slide staining.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Ned Haubein</obo:IAO_0000117>
<obo:IAO_0000119>OBIB, OBI</obo:IAO_0000119>
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<obo:IAO_0000111>single cell specimen</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A cell specimen that contains only one cell.</obo:IAO_0000115>
<obo:IAO_0000116>Requested by Sirarat Sarntivijai (EBI). Details see tracker: https://sourceforge.net/p/obi/obi-terms/828/</obo:IAO_0000116>
<obo:IAO_0000117>PERSON: Jie Zheng, Alexander Diehl</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Jie Zheng, Alexander Diehl</obo:IAO_0000119>
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<!-- http://purl.obolibrary.org/obo/OBI_0002128 -->
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<obo:IAO_0000111>Illumina Genome Analyzer</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A DNA sequencer manufactured by Solexa as one of its first sequencer lines, launched in 2006, and capable of sequencing 1 gigabase (Gb) of data in a single run.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert, Jason Hilton</obo:IAO_0000117>
<obo:IAO_0000118>Illumina Genome Analyzer I</obo:IAO_0000118>
<obo:IAO_0000119>http://www.illumina.com/technology/next-generation-sequencing/solexa-technology.html</obo:IAO_0000119>
<rdfs:label>Illumina Genome Analyzer</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002129 -->
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<obo:IAO_0000111>Illumina HiSeq X Ten</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A DNA sequencer that consists of a set of 10 HiSeq X Sequencing Systems.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert, Jason Hilton, Sagar Jain, Richard Scheuermann</obo:IAO_0000117>
<obo:IAO_0000118>HiSeq X Ten</obo:IAO_0000118>
<obo:IAO_0000119>http://www.illumina.com/systems/hiseq-x-sequencing-system/system.html</obo:IAO_0000119>
<rdfs:label>Illumina HiSeq X Ten</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002130 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001869"/>
<obo:IAO_0000111>Illumina Infinium Omni5Exome-4 Kit</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">An Illumina BeadChip which is an array that interrogates over 4.3 million whole-genome variants for genotyping and copy number variation.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert, Jason Hilton</obo:IAO_0000117>
<obo:IAO_0000119>http://www.illumina.com/products/by-type/microarray-kits/infinium-omni5-exome.html</obo:IAO_0000119>
<rdfs:label>Illumina Infinium Omni5Exome-4 Kit</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002131 -->
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<obo:IAO_0000111>Illumina Infinium MethylationEPIC v1.0 BeadChip</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">An Illumina methylation BeadChip which is an array that interrogates ~ 850,000 methylation sites per sample at single-nucleotide resolution.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert, Jason Hilton</obo:IAO_0000117>
<obo:IAO_0000119>http://www.illumina.com/content/dam/illumina-marketing/documents/products/datasheets/humanmethylationepic-data-sheet-1070-2015-008.pdf</obo:IAO_0000119>
<rdfs:label>Illumina Infinium MethylationEPIC v1.0 BeadChip</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002132 -->
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<obo:IAO_0000111>pulse stable isotope labeling by amino acids in cell culture</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that detects differences in protein abundance using samples that have been metabolically labeled in vivo with a stable non-radioactive heavy isotope containing amino acid for a short period of time. After diluting the pulsed cells into growth media without label, high resolution mass spectrometry-based proteomics is used to analyze the time-dependent decay and determine protein stability.</obo:IAO_0000115>
<obo:IAO_0000117>Rob Nash</obo:IAO_0000117>
<obo:IAO_0000118>dynamic SILAC</obo:IAO_0000118>
<obo:IAO_0000118>pulse SILAC</obo:IAO_0000118>
<obo:IAO_0000118>pulsed SILAC</obo:IAO_0000118>
<obo:IAO_0000119>PMID:18954100</obo:IAO_0000119>
<obo:IAO_0000119>PMID:19053139</obo:IAO_0000119>
<rdfs:label>pulse stable isotope labeling by amino acids in cell culture</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002133 -->
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<obo:IAO_0000111>cytometric bead array assay measuring epitope specific chemokine (C-C motif) ligand 20 production by T cells</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A cytometric bead array assay that detects chemokine (C-C motif) ligand 20 production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, James Overton, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>CCL20/MIP-3a release|cytometric bead array</obo:OBI_9991118>
<rdfs:label>cytometric bead array assay measuring epitope specific chemokine (C-C motif) ligand 20 production by T cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002134 -->
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<obo:IAO_0000115 xml:lang="en">A T cell epitope specific cytokine production assay that detects chemokine (C-C motif) ligand 20 production by T cells.</obo:IAO_0000115>
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<!-- http://purl.obolibrary.org/obo/OBI_0002136 -->
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<obo:IAO_0000111>RNA Integrity Number calculation</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A data transformation using the RIN algorithm to generate a quality measure of RNA based on features from an electrophoretic trace.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000118>RIN calculation</obo:IAO_0000118>
<obo:IAO_0000119>https://www.agilent.com/cs/library/applications/5989-1165EN.pdf</obo:IAO_0000119>
<rdfs:label xml:lang="en">RNA Integrity Number calculation</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002137 -->
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<obo:IAO_0000111>RNA Integrity Number value specification</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A value specification that specifies the value of the RNA Integrity Number as a real value between 1 (most degraded) and 10 (most intact).</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000118>RIN value specification</obo:IAO_0000118>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">RNA Integrity Number value specification</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002138 -->
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<obo:IAO_0000111>temperature value specification</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A value specification that specifies the temperature of some thing.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">temperature value specification</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002139 -->
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<obo:IAO_0000111>volume value specification</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A value specification that specifies the volume of some thing.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">volume value specification</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002140 -->
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<obo:IAO_0000111>temperature measurement assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An assay to determine the temperature of an evaluant.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>temperature measurement assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002141 -->
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<obo:IAO_0000111>volume measurement assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An assay to determine the volume of an evaluant.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>volume measurement assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002142 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001926"/>
<obo:IAO_0000111>Nanostring nCounter miRNA expression assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A microRNA profiling assay using digital molecular barcoding technology to quantify target microRNA molecules without the need for amplification.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jason Hilton</obo:IAO_0000117>
<obo:IAO_0000118>microRNA counts</obo:IAO_0000118>
<obo:IAO_0000119>PMID:26729350</obo:IAO_0000119>
<obo:IAO_0000119>url:http://www.nanostring.com/applications/technology</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/806</obo:IAO_0000233>
<obo:IAO_0000234>ENCODE DCC</obo:IAO_0000234>
<rdfs:label>Nanostring nCounter miRNA expression assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002143 -->
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<obo:IAO_0000111>bromouride labeling and sequencing after UV exposure</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An RNA-seq assay to identify transcription start sites and active enhancer elements through isolation of bromouridine (Bru) labelled RNAs after UV light exposure introduces transcription-blocking lesions.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jason Hilton</obo:IAO_0000117>
<obo:IAO_0000118>BruUV-seq</obo:IAO_0000118>
<obo:IAO_0000119>PMC:4675984</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/827</obo:IAO_0000233>
<obo:IAO_0000234>ENCODE DCC</obo:IAO_0000234>
<rdfs:label>bromouride labeling and sequencing after UV exposure</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002144 -->
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<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An assay which aims at identifying the endogenous population of extrachromosomal circular DNA originating from a subset of genomic loci and potentially having profound consequences on the regulatory and coding capabilities of these regions. The assay includes creation of a library out of the circular DNA molecules and subsequent sequencing using parallelized sequencing methods.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jason Hilton</obo:IAO_0000117>
<obo:IAO_0000118>circulome-seq</obo:IAO_0000118>
<obo:IAO_0000118>eccDNA-seq</obo:IAO_0000118>
<obo:IAO_0000119>url:http://biorxiv.org/content/early/2017/04/19/128686</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/830</obo:IAO_0000233>
<obo:IAO_0000234>ENCODE DCC</obo:IAO_0000234>
<rdfs:label>extrachromosomal circular DNA sequencing assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002145 -->
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<obo:IAO_0000112>Test performed using antibodies produced by human B-cells that bind with human immunodeficiency virus (HIV) antigens</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the presence or amount of antibodies to a specified antigen.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>James Overton</obo:IAO_0000117>
<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/825</obo:IAO_0000233>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>antigen specific antibodies assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002146 -->
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<obo:IAO_0000111>HIV antibody assay</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">An antigen specific antibodies assay that is meant to detect antibodies that bind to human immunodeficiency virus (HIV) antigens.</obo:IAO_0000115>
<obo:IAO_0000116>HIV-1 and HIV-2 are two different viruses (http://i-base.info/qa/36)</obo:IAO_0000116>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>James Overton</obo:IAO_0000117>
<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
<obo:IAO_0000118>HIV I/II Ab assay</obo:IAO_0000118>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/825</obo:IAO_0000233>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>HIV antibody assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002147 -->
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<obo:IAO_0000111>HIV group O antibody assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An antigen specific antibodies assay that is meant to detect antibodies that bind to human immunodeficiency virus (HIV) group O antigens.</obo:IAO_0000115>
<obo:IAO_0000116>https://www.cdc.gov/mmwr/preview/mmwrhtml/00042810.htm</obo:IAO_0000116>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>James Overton</obo:IAO_0000117>
<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
<obo:IAO_0000118>HIV I/II Plus O assay</obo:IAO_0000118>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/825</obo:IAO_0000233>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>HIV group O antibody assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002148 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002148">
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<obo:IAO_0000111>surface HBV antibody assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An antigen specific antibodies assay that is meant to detect antibodies that bind to hepatitis B virus (HBV) surface antigens.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>James Overton</obo:IAO_0000117>
<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
<obo:IAO_0000118>HBsAb assay</obo:IAO_0000118>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/825</obo:IAO_0000233>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>surface HBV antibody assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002149 -->
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<obo:IAO_0000111>core HBV antibody assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An antigen specific antibodies assay that is meant to detect antibodies that bind to hepatitis B virus (HBV) core antigens.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>James Overton</obo:IAO_0000117>
<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
<obo:IAO_0000118>HBcAb assay</obo:IAO_0000118>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/825</obo:IAO_0000233>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>core HBV antibody assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002150 -->
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<obo:IAO_0000111>core HBV IgM antibody assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An antigen specific antibodies assay that is meant to detectimmunoglobulin M (IgM) antibodies that bind to hepatitis B virus (HBV) core antigens.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>James Overton</obo:IAO_0000117>
<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
<obo:IAO_0000118>HBcAb-IgM assay</obo:IAO_0000118>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/825</obo:IAO_0000233>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>core HBV IgM antibody assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002151 -->
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<obo:IAO_0000111>HCV antibody assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An antigen specific antibodies assay that is meant to detect antibodies that bind to Hepacivirus C (HCV) antigens.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>James Overton</obo:IAO_0000117>
<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
<obo:IAO_0000118>HCV Ab assay</obo:IAO_0000118>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/825</obo:IAO_0000233>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
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<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An antigen specific antibodies assay that is meant to detect immunoglobulin G (IgG) antibodies that bind to Epstein-Barr virus (EBV) antigens.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>James Overton</obo:IAO_0000117>
<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
<obo:IAO_0000118>EBV IgG Ab assay</obo:IAO_0000118>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/825</obo:IAO_0000233>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
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<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An antigen specific antibodies assay that is meant to detect immunoglobulin M (IgM) antibodies that bind to Epstein-Barr virus (EBV) antigens.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>James Overton</obo:IAO_0000117>
<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
<obo:IAO_0000118>EBV IgM Ab assay</obo:IAO_0000118>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/825</obo:IAO_0000233>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>EBV IgM antibody assay</rdfs:label>
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<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An antigen specific antibodies assay that is meant to detect antibodies that bind to cytomegalovirus (CMV) antigens.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>James Overton</obo:IAO_0000117>
<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
<obo:IAO_0000118>CMV Ab assay</obo:IAO_0000118>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/825</obo:IAO_0000233>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>CMV antibody assay</rdfs:label>
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<obo:IAO_0000111>venereal disease research laboratory test</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that is meant to detect general antibodies that react with substances that are produced by cellular damage caused by Treponema pallidum indicating a syphilis infection. VDRL tests require a microscope and can be done on cerebrospinal fluid as well as blood.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>James Overton</obo:IAO_0000117>
<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
<obo:IAO_0000118>VDRL test</obo:IAO_0000118>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/825</obo:IAO_0000233>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>venereal disease research laboratory test</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002156 -->
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<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that is meant to detect with the aid of carbon or charcoal particles general antibodies that react with substances that are produced by cellular damage caused by Treponema pallidum indicating a syphilis infection. RPR tests can be done without a microscope.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>James Overton</obo:IAO_0000117>
<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
<obo:IAO_0000118>RPR assay</obo:IAO_0000118>
<obo:IAO_0000119>url:http://www.differencebetween.net/science/health/difference-between-vdlr-and-rpr/</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/825</obo:IAO_0000233>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>rapid plasma reagin test</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002157 -->
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<obo:IAO_0000111>HBV surface antigen assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that is meant to detect hepatitis B virus (HBV) surface antigens.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>James Overton</obo:IAO_0000117>
<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
<obo:IAO_0000118>HBsAg assay</obo:IAO_0000118>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/825</obo:IAO_0000233>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>HBV surface antigen assay</rdfs:label>
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<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that is meant to detect human immunodeficiency virus (HIV-1) nucleic acids.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>James Overton</obo:IAO_0000117>
<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
<obo:IAO_0000118>HIV-1 NAT</obo:IAO_0000118>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/825</obo:IAO_0000233>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>HIV-1 nucleic acid testing</rdfs:label>
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<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that is meant to detect hepatitis C virus (HCV) nucleic acids.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>James Overton</obo:IAO_0000117>
<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
<obo:IAO_0000118>HCV NAT</obo:IAO_0000118>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/825</obo:IAO_0000233>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>HCV nucleic acid testing</rdfs:label>
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<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A ChIP-seq assay which leverages T7 promoter amplification to allow low sample input and chromatin barcoding and pool-and-split multiplexing for high-throughput, quantitative profiling of chromatin states.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jason Hilton</obo:IAO_0000117>
<obo:IAO_0000118>Mint-ChIP</obo:IAO_0000118>
<obo:IAO_0000118>Mint-ChIP-seq</obo:IAO_0000118>
<obo:IAO_0000119>url:http://www.cell.com/molecular-cell/abstract/S1097-2765(15)00863-1</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/829</obo:IAO_0000233>
<obo:IAO_0000234>ENCODE DCC</obo:IAO_0000234>
<rdfs:label>multiplexed indexed T7 ChIP-seq assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002161 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002161">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001146"/>
<obo:IAO_0000111>systematic evolution of ligands by exponential enrichment assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A binding assay that identifies protein-binding sites on nucleic acids by selecting high-affinity target ligands from a randomized pool. The process is repeated in rounds, then the bound nucleic acids are separated from the unbound nucleic acids and amplified by PCR._</obo:IAO_0000115>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000118>SELEX</obo:IAO_0000118>
<obo:IAO_0000119>PMID:21720957</obo:IAO_0000119>
<rdfs:label>systematic evolution of ligands by exponential enrichment assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002162 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002162">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>footprinting assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures ligand binding and conformational changes by the solvent accessibility of the backbone, bases, or side-chain structures of macromolecules through their sensitivity to chemical or enzymatic cleavage or modification reactions.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>doi:10.1002/3527600906.mcb.200300025</obo:IAO_0000119>
<rdfs:label>footprinting assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002163 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002163">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002162"/>
<obo:IAO_0000111>DNAse footprinting assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An enzymatic footprinting assay that determines protein-binding sites on DNA by identifying bound fragments that are protected from DNAse I-catalyzed hydrolysis</obo:IAO_0000115>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000119>OBI development call</obo:IAO_0000119>
<rdfs:label>DNAse footprinting assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002164 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002164">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001146"/>
<obo:IAO_0000111>mammalian 2-hybrid assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A binding assay that increases the expression of a reporter gene in mammalian cells by proteins of interest attached to two portions of the transcriptional activator, bringing those portions closer together.</obo:IAO_0000115>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000119>ECO:0001095</obo:IAO_0000119>
<obo:IAO_0000119>PMID:9043710</obo:IAO_0000119>
<rdfs:label>mammalian 2-hybrid assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002165 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002165">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>protein localization assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that determines the specific location of a protein. Subcellular localization is distinguished from tissue-based localization based on the type of microscopy applied.</obo:IAO_0000115>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000119>OBI development call</obo:IAO_0000119>
<rdfs:label>protein localization assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002166 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002166">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002165"/>
<obo:IAO_0000111>tissue-based protein localization assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A protein localization assay that determines the specific location of a protein in a living tissue sample.</obo:IAO_0000115>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000119>PMID:14686950</obo:IAO_0000119>
<rdfs:label>tissue-based protein localization assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002167 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002167">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002165"/>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000990"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000990"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>subcellular protein localization assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A protein localization assay that determines the specific subcellular location of a protein. The location is visualized through electron microscopy.</obo:IAO_0000115>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000119>ECO</obo:IAO_0000119>
<rdfs:label>subcellular protein localization assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002168 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002168">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001986"/>
<obo:IAO_0000111>subcellular protein immunohistochemistry assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An immunohistochemistry assay that uses antibodies to display the specific subcellular location of proteins.</obo:IAO_0000115>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000119>ECO</obo:IAO_0000119>
<rdfs:label>subcellular protein immunohistochemistry assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002169 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002169">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001954"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002692"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000893"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003368"/>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>ChIP-qPCR assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A ChIP assay that uses quantitative PCR to determine levels of specific DNA in immunoprecipitated samples.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>PMID:18388953</obo:IAO_0000119>
<rdfs:label>ChIP-qPCR assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002170 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002170">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002161"/>
<obo:IAO_0000111>genomic SELEX</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A systematic evolution of ligands by exponential enrichment assay that starts with a library derived from genomic DNA instead of synthetically derived random DNA molecules.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>PMID:20541015</obo:IAO_0000119>
<rdfs:label>genomic SELEX</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002171 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002171">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<obo:IAO_0000111>dot blot assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that detects molecules in a mixture dotted on a membrane using DNA probes or antibodies.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000118>dot blot analysis</obo:IAO_0000118>
<obo:IAO_0000119>PMID:10473518</obo:IAO_0000119>
<rdfs:label>dot blot assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002172 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002172">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001591"/>
<obo:IAO_0000111>Northwestern blot assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A direct binding assay that detects interactions of labeled RNA with immobilized protein on a membrane.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000118>Northwestern analysis</obo:IAO_0000118>
<obo:IAO_0000118>Northwestern assay</obo:IAO_0000118>
<obo:IAO_0000119>PMID:26965261</obo:IAO_0000119>
<rdfs:label>Northwestern blot assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002173 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002173">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001591"/>
<obo:IAO_0000111>Southwestern blot assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A direct binding assay that detects interactions of labeled DNA with immobilized protein on a membrane.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>PMID:26404144</obo:IAO_0000119>
<rdfs:label>Southwestern blot assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002174 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002174">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001632"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001977"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000000"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>immunocytochemistry</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An immuno staining assay in which samples of intact cells are examined that have had most, if not all, of their surrounding extracellular matrix removed</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<rdfs:label>immunocytochemistry</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002175 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002175">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_15422"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_15422"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>ATP bioluminescence assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that detects ATP concentration through light intensity when luciferase catalyzes the oxidation of luciferin in the presence of ATP, magnesium ions, and molecular oxygen.</obo:IAO_0000115>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000118>ATP quantitation assay</obo:IAO_0000118>
<obo:IAO_0000118>cell viability ATP quantitation assay</obo:IAO_0000118>
<obo:IAO_0000119>ECO</obo:IAO_0000119>
<rdfs:label>ATP bioluminescence assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002176 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002176">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>electrophysiology assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures the electrical properties of biological cells or tissues. Typically, this assay will generate measurements of voltage changes or electric current (or other associated variables such as impedence or capacitance).</obo:IAO_0000115>
<obo:IAO_0000116>Note that electrophysiological manipulations also exist which involve processes that alter the electrophysiological properties of cells and tissues.</obo:IAO_0000116>
<obo:IAO_0000117>Gully Burns</obo:IAO_0000117>
<obo:IAO_0000119>url:https://en.wikipedia.org/wiki/Electrophysiology</obo:IAO_0000119>
<rdfs:label>electrophysiology assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002177 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002177">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000447"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001080"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001080"/>
</owl:Restriction>
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</rdfs:subClassOf>
<obo:IAO_0000111>patch clamp assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An intracellular electrophysiology assay where a glass micropipette is sealed to the surface of the cell membrane as a recording electrode to study ion channel activity. The key distinction of this technique is the electrical resistance of the seal between the cell membrane and the pipette is of the order 10-100 gigaohms, permitting high-resolution current measurements over the cell membrane in several different standard configurations.</obo:IAO_0000115>
<obo:IAO_0000117>Gully Burns</obo:IAO_0000117>
<obo:IAO_0000119>ECO:0006012</obo:IAO_0000119>
<obo:IAO_0000119>url:http://www.annualreviews.org/doi/pdf/10.1146/annurev.ph.46.030184.002323</obo:IAO_0000119>
<obo:IAO_0000119>url:https://en.wikipedia.org/wiki/Patch_clamp</obo:IAO_0000119>
<rdfs:label>patch clamp assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002178 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002178">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002177"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001080"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001080"/>
</owl:Restriction>
</owl:intersectionOf>
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</rdfs:subClassOf>
<obo:IAO_0000111>whole-cell patch clamp assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A patch-clamp assay where the electrode is left in place on the cell, as in cell-attached recordings, but the membrane patch has been perforated, providing access from the interior of the pipette to the intracellular space of the cell. Measurements made with this technique involve recording currents through multiple channels simultaneously, over the membrane of the entire cell.</obo:IAO_0000115>
<obo:IAO_0000117>Gully Burns</obo:IAO_0000117>
<obo:IAO_0000119>ECO:0006015</obo:IAO_0000119>
<obo:IAO_0000119>url:https://en.wikipedia.org/wiki/Patch_clamp#Whole-cell_recording_or_whole-cell_patch</obo:IAO_0000119>
<rdfs:label>whole-cell patch clamp assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002179 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002179">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002177"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001080"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001080"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>cell-attached patch clamp assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A patch-clamp assay where the electrode is left in place on the cell, and the membrane patch has been left intact been perforated. This maintains the separation of the interior of the pipette to the intracellular space of the cell. Measurements made with this technique involve recording currents through multiple channels simultaneously, over the membrane of the entire cell.</obo:IAO_0000115>
<obo:IAO_0000117>Gully Burns</obo:IAO_0000117>
<obo:IAO_0000119>url:https://en.wikipedia.org/wiki/Patch_clamp#Cell-attached_patch</obo:IAO_0000119>
<rdfs:label>cell-attached patch clamp assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002180 -->
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<obo:IAO_0000111>inside-out patch clamp assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A patch-clamp assay where a patch of the membrane is attached to the patch pipette, detached from the rest of the cell, and the cytosolic surface of the membrane is exposed to the external media, or bath. This provides the experimenter has access to the intracellular surface of the membrane via the bath and can manipulate the environment at the intracellular surface of single ion channels. For example, channels that are activated by intracellular ligands can then be studied through a range of ligand concentrations.</obo:IAO_0000115>
<obo:IAO_0000117>Gully Burns</obo:IAO_0000117>
<obo:IAO_0000119>url:http://www.leica-microsystems.com/science-lab/the-patch-clamp-technique/</obo:IAO_0000119>
<obo:IAO_0000119>url:https://en.wikipedia.org/wiki/Patch_clamp#Inside-out_patch</obo:IAO_0000119>
<rdfs:label>inside-out patch clamp assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002181 -->
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<obo:IAO_0000111>outside-out patch clamp assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A patch-clamp assay where a patch of the membrane is attached to the patch pipette. In this configuration, the external surface of the cell membrane is exposed as the outside of the membrane patch relative to the patch electrode. An outside-out patch starts with a gigaohm seal in a whole-cell recording configuration. The electrode is slowly withdrawn from the cell, until a fragment of membrane bulges away from the cell, which detaches and reforms as a convex membrane on the end of the electrode, with the original external surface of the membrane facing outward from the electrode. This provides the experimenter with access to the extracellular surface of the membrane via the bath and can manipulate the environment at the extracellular surface of single ion channels.</obo:IAO_0000115>
<obo:IAO_0000117>Gully Burns</obo:IAO_0000117>
<obo:IAO_0000119>url:http://www.leica-microsystems.com/science-lab/the-patch-clamp-technique/</obo:IAO_0000119>
<obo:IAO_0000119>url:https://en.wikipedia.org/wiki/Patch_clamp#Outside-out_patch</obo:IAO_0000119>
<rdfs:label>outside-out patch clamp assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002182 -->
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<obo:IAO_0000111>voltage clamp assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An cellular electrophysiology assay where the membrane potential of a cell is controlled by the experimentalist. This is accomplished through a feedback mechanism where any change in membrane potential is countered by permitting electrical current to flow into or out of the cell.</obo:IAO_0000115>
<obo:IAO_0000117>Gully Burns</obo:IAO_0000117>
<obo:IAO_0000119>url:https://en.wikipedia.org/wiki/Voltage_clamp</obo:IAO_0000119>
<rdfs:label>voltage clamp assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002183 -->
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<obo:IAO_0000111>two electrode voltage clamp assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The two electrode voltage clamp (TEVC) method utilizes two low-resistance pipettes, one sensing voltage and the other injecting current. The microelectrodes are filled with conductive solution and inserted into the cell to artificially control membrane potential. The membrane acts as a dielectric as well as a resistor, while the fluids on either side of the membrane function as capacitors.[9] The microelectrodes compare the membrane potential against a command voltage, giving an accurate reproduction of the currents flowing across the membrane. Current readings can be used to analyze the electrical response of the cell to different applications. This technique is mainly used in the Oocyte preparation.</obo:IAO_0000115>
<obo:IAO_0000117>Gully Burns</obo:IAO_0000117>
<obo:IAO_0000118>TEVC</obo:IAO_0000118>
<obo:IAO_0000119>url:https://en.wikipedia.org/wiki/Voltage_clamp#Two-electrode_voltage_clamp_using_microelectrodes</obo:IAO_0000119>
<rdfs:label>two electrode voltage clamp assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002184 -->
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<obo:IAO_0000111>cut open oocyte voltage clamp assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The cut-open oocyte Vaseline gap (COVG) voltage-clamp technique is designed to solve weaknesses in the two elextrode voltage clamp by maximizing the benefits of the Xenopus oocyte expression system by improving on clamp speed, signal-to-noise ratio, and ability to effectively perfuse the oocyte. In this way, it was possible to combine the most popular transient expression system, and the associated benefits of molecular cloning and site-directed mutagenesis, with the superior voltage-clamp properties of cut-open cell techniques.</obo:IAO_0000115>
<obo:IAO_0000117>Gully Burns</obo:IAO_0000117>
<obo:IAO_0000118>COVG</obo:IAO_0000118>
<obo:IAO_0000119>PMID:9711615</obo:IAO_0000119>
<rdfs:label>cut open oocyte voltage clamp assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002185 -->
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<obo:IAO_0000111>current clamp assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The current clamp technique records the membrane potential by injecting current into a cell through the recording electrode. Unlike in the voltage clamp mode, where the membrane potential is held at a level determined by the experimenter, in "current clamp" mode the membrane potential is free to vary, and the amplifier records whatever voltage the cell generates on its own or as a result of stimulation. This technique is used to study how a cell responds when electric current enters a cell; this is important for instance for understanding how neurons respond to neurotransmitters that act by opening membrane ion channels.</obo:IAO_0000115>
<obo:IAO_0000117>Gully Burns</obo:IAO_0000117>
<obo:IAO_0000119>url:https://en.wikipedia.org/wiki/Electrophysiology#Current_clamp</obo:IAO_0000119>
<rdfs:label>current clamp assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002186 -->
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<obo:IAO_0000111>electroencephalography</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An extracellular electrophysiology assay where electrodes are mounted outside the brain (either on the surface of the scalp on onto the brain surface itself during surgery) to measure the electrical field over the external surface.</obo:IAO_0000115>
<obo:IAO_0000117>Gully Burns</obo:IAO_0000117>
<obo:IAO_0000118>EEG</obo:IAO_0000118>
<rdfs:label>electroencephalography</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002187 -->
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<obo:IAO_0000111>single-unit recording</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An extracellular electrophysiology assay where a single microelectrode is placed in close proximity to a single neuron to measure voltage and current changes over time. This is the technicque used by Hubel and Wiesel to measure firing properties of primary visual cortex neurons in the 1950s in their original Nobel-prize winning study. A classic, old technique.</obo:IAO_0000115>
<obo:IAO_0000116>Can be used on any cell, not just neurons.</obo:IAO_0000116>
<obo:IAO_0000117>Gully Burns</obo:IAO_0000117>
<obo:IAO_0000119>url:http://www.thieme.com/media/samples/pubid-80418214.pdf</obo:IAO_0000119>
<rdfs:label>single-unit recording</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002188 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000454"/>
<obo:IAO_0000111>multi-unit recording</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An extracellular electrophysiology assay where a collection of microelectrodes (often in an 'array' configuration) is placed into neural tissue to measure the distribution of voltage and current changes for a population of cells over time.</obo:IAO_0000115>
<obo:IAO_0000117>Gully Burns</obo:IAO_0000117>
<rdfs:label>multi-unit recording</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002189 -->
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<obo:IAO_0000111>local field potential recording</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An extracellular electrophysiology assay where a microelectrode is placed in the extracellular space of brain tissue to measure action potential and compared to an electrode either outside or inside that tissue.</obo:IAO_0000115>
<obo:IAO_0000117>Gully Burns</obo:IAO_0000117>
<obo:IAO_0000119>doi:10.1007/978-1-4614-7320-6_723-1</obo:IAO_0000119>
<rdfs:label>local field potential recording</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002190 -->
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<obo:IAO_0000111>courier organization</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An organization that delivers messages, packages, and mail.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>courier</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Courier</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label xml:lang="en">courier organization</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002191 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002191">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000577"/>
<obo:IAO_0000111>courier tracking number</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A centrally registered identifier symbol assigned by a courier organization in order to track the delivery of an item.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label xml:lang="en">courier tracking number</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002192 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002192">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001064"/>
<obo:IAO_0000111>Leica Peloris rapid tissue processor</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An automatic tissue processor that is a dual retort tissue processor manufactured by the Leica company to provide fast, high quality tissue processing for histology laboratories.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>http://drp8p5tqcb2p5.cloudfront.net/fileadmin/downloads_lbs/Leica%20PELORIS/User%20Manuals/Leica_Peloris_manual_EN.pdf</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Leica Peloris rapid tissue processor</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002194 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002194">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400168"/>
<obo:IAO_0000111>Microm Ergostar HM200</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A microtome that is manufactured by Microm and uses a vertical cutting stroke common to all rotary microtomes engaged by a horizontal sliding movement. An operating arm replaces the handwheel and is attached to both sides of the instrument for greater convenience to permit control of sectioning from the left or right.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>http://www.ultra-medical.com/Microm-Ergostar-HM200-Microtome/en</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Microm Ergostar HM200</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002195 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002195">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<obo:IAO_0000111>microtome blade</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A device that is the part of a microtome used to slice specimens to a desired thickness.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Microtome</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>microtome blade</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002196 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002196">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002195"/>
<obo:IAO_0000111>Sakura Low profile Accu-Edge microtome blade</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A microtome blade that is manufactured by Feather and is disposable. The ultra-sharp blades section specimens without striations, distortion or chattering.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>http://www.sakura.eu/Our-products/item/8/Microtomy/29/Accu-Edge-Disposable-Microtome-Blades</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Sakura Low profile Accu-Edge microtome blade</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002197 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002197">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000408"/>
<obo:IAO_0000111>tissue section thickness</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A length measurement datum that is the result of an assay measuring the thickness of a tissue section.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label xml:lang="en">tissue section thickness</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002198 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002198">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000245"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000947"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001547"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000245"/>
<obo:IAO_0000111>molecular analysis facility organization</obo:IAO_0000111>
<obo:IAO_0000112>An analysis facility that includes analysis of molecular metabolites, as well as the various DNAs and RNAs.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An organization that provides molecular analysis service.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>MAF</obo:IAO_0000118>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label xml:lang="en">molecular analysis facility organization</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002199 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002199">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
<obo:IAO_0000111>reason for lack of data item</obo:IAO_0000111>
<obo:IAO_0000112>cannot be assessed, not applicable, unknown</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An information content entity that provides an explanation why a data item is not provided.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>reason for lack of data item</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002200 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002200">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002199"/>
<obo:IAO_0000111>cannot be assessed determination</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A reason for lack of data item that is the negative output of a determination if assay will provide reliable results.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>cannot be assessed</obo:IAO_0000118>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>cannot be assessed determination</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002201 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002201">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<obo:IAO_0000111>determination if assay will provide reliable results</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A planned process that is used to assess whether an assay will provide reliable results based on the conditions or qualities of the inputs, devices, and other participants of the assay.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>determination if assay will provide reliable results</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002202 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002202">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002200"/>
<obo:IAO_0000111>GX</obo:IAO_0000111>
<obo:IAO_0000112>AJCC 7th edition GX: cannot be assessed.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cannot be assessed determination for histologic tumor grade.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>GX</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002203 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002203">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002200"/>
<obo:IAO_0000111>pTX</obo:IAO_0000111>
<obo:IAO_0000112>AJCC 7th edition pTX: cannot be assessed.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cannot be assessed determination for pathologic primary tumor staging.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pTX</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002204 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002204">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002200"/>
<obo:IAO_0000111>pNX</obo:IAO_0000111>
<obo:IAO_0000112>AJCC 7th edition pNX: cannot be assessed.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cannot be assessed determination of pathologic staging of lymph nodes.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pNX</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002205 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002205">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001930"/>
<obo:IAO_0000111>histologic grade according to AJCC 7th edition</obo:IAO_0000111>
<obo:IAO_0000112>G1:Well differentiated</obo:IAO_0000112>
<obo:IAO_0000112>G4: Undifferentiated</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A categorical value specification that is a histologic grade assigned to a tumor slide specimen according to the American Joint Committee on Cancer (AJCC) 7th Edition grading system.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>histologic grade according to AJCC 7th edition</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002210 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002210">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001930"/>
<obo:IAO_0000111>histologic grade according to the Fuhrman Nuclear Grading System</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A categorical value specification that is a histologic grade assigned to a tumor slide specimen according to the Fuhrman Nuclear Grading System.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Histologic Grade (Fuhrman Nuclear Grading System)</obo:IAO_0000118>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>histologic grade according to the Fuhrman Nuclear Grading System</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002215 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002215">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001930"/>
<obo:IAO_0000111>histologic grade for ovarian tumor</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A categorical value specification that is a histologic grade assigned to a ovarian tumor.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>histologic grade for ovarian tumor</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002216 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002216">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002215"/>
<obo:IAO_0000111>histologic grade for ovarian tumor according to a two-tier grading system</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A histologic grade for ovarian tumor that is from a two-tier histological classification of tumors.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>histologic grade for ovarian tumor according to a two-tier grading system</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002219 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002219">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002215"/>
<obo:IAO_0000111>histologic grade for ovarian tumor according to the World Health Organization</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A histologic grade for ovarian tumor that is from a histological classification by the World Health Organization (WHO).</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>histologic grade for ovarian tumor according to the World Health Organization</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002224 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002224">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001930"/>
<obo:IAO_0000111>pathologic primary tumor stage for colon and rectum according to AJCC 7th edition</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A categorical value specification that is a pathologic finding about one or more characteristics of colorectal cancer following the rules of the TNM American Joint Committee on Cancer (AJCC) version 7 classification system as they pertain to staging of the primary tumor. TNM pathologic primary tumor findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>pT: Pathologic spread colorectal primary tumor (AJCC 7th Edition)</obo:IAO_0000118>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pathologic primary tumor stage for colon and rectum according to AJCC 7th edition</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002232 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002232">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001930"/>
<obo:IAO_0000111>pathologic primary tumor stage for lung according to AJCC 7th edition</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A categorical value specification that is a pathologic finding about one or more characteristics of lung cancer following the rules of the TNM American Joint Committee on Cancer (AJCC) version 7 classification system as they pertain to staging of the primary tumor. TNM pathologic primary tumor findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>pT: Pathologic spread lung primary tumor (AJCC 7th Edition)</obo:IAO_0000118>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pathologic primary tumor stage for lung according to AJCC 7th edition</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002243 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002243">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001930"/>
<obo:IAO_0000111>pathologic primary tumor stage for kidney according to AJCC 7th edition</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A categorical value specification that is a pathologic finding about one or more characteristics of renal cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor. TNM pathologic primary tumor findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>pT: Pathologic spread kidney primary tumor (AJCC 7th Edition)</obo:IAO_0000118>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pathologic primary tumor stage for kidney according to AJCC 7th edition</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002256 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002256">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001930"/>
<obo:IAO_0000111>pathologic primary tumor stage for ovary according to AJCC 7th edition</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A categorical value specification that is a pathologic finding about one or more characteristics of ovarian cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor. TNM pathologic primary tumor findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>pT: Pathologic spread ovarian primary tumor (AJCC 7th Edition)</obo:IAO_0000118>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pathologic primary tumor stage for ovary according to AJCC 7th edition</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002270 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002270">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001930"/>
<obo:IAO_0000111>pathologic lymph node stage for colon and rectum according to AJCC 7th edition</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A categorical value specification that is a pathologic finding about one or more characteristics of colorectal cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>pN: Pathologic spread colon lymph nodes (AJCC 7th Edition)</obo:IAO_0000118>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pathologic lymph node stage for colon and rectum according to AJCC 7th edition</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002279 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002279">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001930"/>
<obo:IAO_0000111>pathologic lymph node stage for lung according to AJCC 7th edition</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A categorical value specification that is a pathologic finding about one or more characteristics of lung cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>pN: Pathologic spread colon lymph nodes (AJCC 7th Edition)</obo:IAO_0000118>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pathologic lymph node stage for lung according to AJCC 7th edition</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002284 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002284">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001930"/>
<obo:IAO_0000111>pathologic lymph node stage for kidney according to AJCC 7th edition</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A categorical value specification that is a pathologic finding about one or more characteristics of renal cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>pN: Pathologic spread kidney lymph nodes (AJCC 7th Edition)</obo:IAO_0000118>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pathologic lymph node stage for kidney according to AJCC 7th edition</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002287 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002287">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001930"/>
<obo:IAO_0000111>pathologic lymph node stage for ovary according to AJCC 7th edition</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A categorical value specification that is a pathologic finding about one or more characteristics of ovarian cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>pN: Pathologic spread ovarian lymph nodes (AJCC 7th Edition)</obo:IAO_0000118>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pathologic lymph node stage for ovary according to AJCC 7th edition</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002290 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002290">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001930"/>
<obo:IAO_0000111>pathologic distant metastases stage for colon according to AJCC 7th edition</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A categorical value specification that is a pathologic finding about one or more characteristics of colon cancer following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases. TNM pathologic distant metastasis findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>M: colon distant metastases (AJCC 7th Edition)</obo:IAO_0000118>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pathologic distant metastases stage for colon according to AJCC 7th edition</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002298 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002298">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001930"/>
<obo:IAO_0000111>pathologic distant metastases stage for lung according to AJCC 7th edition</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A categorical value specification that is a pathologic finding about one or more characteristics of lung cancer following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases. TNM pathologic distant metastasis findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>M: lung distant metastases (AJCC 7th Edition)</obo:IAO_0000118>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pathologic distant metastases stage for lung according to AJCC 7th edition</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002306 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002306">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001930"/>
<obo:IAO_0000111>pathologic distant metastases stage for kidney according to AJCC 7th edition</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A categorical value specification that is a pathologic finding about one or more characteristics of renal cancer following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases. TNM pathologic distant metastasis findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>M: kidney distant Metastases (AJCC 7th Edition)</obo:IAO_0000118>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pathologic distant metastases stage for kidney according to AJCC 7th edition</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002310 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002310">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001930"/>
<obo:IAO_0000111>pathologic distant metastases stage for ovary according to AJCC 7th edition</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A categorical value specification that is a pathologic finding about one or more characteristics of ovarian cancer following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases. TNM pathologic distant metastasis findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>M: ovarian distant metastases (AJCC 7th Edition)</obo:IAO_0000118>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pathologic distant metastases stage for ovary according to AJCC 7th edition</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002314 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002314">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001930"/>
<obo:IAO_0000111>clinical tumor stage group according to AJCC 7th edition</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A categorical value specification that is an assessment of the stage of a cancer according to the American Joint Committee on Cancer (AJCC) v7 staging systems.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Clinical tumor stage group (AJCC 7th Edition)</obo:IAO_0000118>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>clinical tumor stage group according to AJCC 7th edition</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002326 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002326">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001930"/>
<obo:IAO_0000111>International Federation of Gynecology and Obstetrics cervical cancer stage value specification</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A categorical value specification that is an assessment of the stage of a gynecologic cancer according to the International Federation of Gynecology and Obstetrics (FIGO) staging systems.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Clinical FIGO stage</obo:IAO_0000118>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>International Federation of Gynecology and Obstetrics cervical cancer stage value specification</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002341 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002341">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001930"/>
<obo:IAO_0000111>International Federation of Gynecology and Obstetrics ovarian cancer stage value specification</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A categorical value specification that is a pathologic finding about one or more characteristics of ovarian cancer following the rules of the FIGO classification system.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Pathologic Tumor Stage Grouping for ovarian cancer (FIGO)</obo:IAO_0000118>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>International Federation of Gynecology and Obstetrics ovarian cancer stage value specification</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002356 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002356">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001930"/>
<obo:IAO_0000111>performance status value specification</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A categorical value specification that is an assessment of a participant's performance status (general well-being and activities of daily life).</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Performance Status Scale</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Performance_status</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>performance status value specification</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002357 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002357">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002356"/>
<obo:IAO_0000111>Eastern Cooperative Oncology Group score value specification</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A performance status value specification designed by the Eastern Cooperative Oncology Group to assess disease progression and its affect on the daily living abilities of the patient.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>ECOG score</obo:IAO_0000118>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Eastern Cooperative Oncology Group score value specification</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002363 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002363">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002356"/>
<obo:IAO_0000111>Karnofsky score vaue specification</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A performance status value specification designed for classifying patients 16 years of age or older by their functional impairment.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Karnofsky Score</obo:IAO_0000118>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Karnofsky score vaue specification</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002368 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002368">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000015"/>
<obo:IAO_0000111>clinical history of cancer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A clinical history in which there is a diagnosis of cancer.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>clinical history of cancer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002369 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002369">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000015"/>
<obo:IAO_0000111>clinical history devoid of cancer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A clinical history in which there was no diagnosis of cancer.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>clinical history of no cancer</obo:IAO_0000118>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>clinical history devoid of cancer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002370 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002370">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000015"/>
<obo:IAO_0000111>unknown clinical history of cancer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A clinical history in which it is not known whether there was a diagnosis of cancer.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>unknown clinical history of cancer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002371 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002371">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000073"/>
<obo:IAO_0000111>diagnosis of cancer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A diagnosis that is an assertion that a patient who is the subject of a diagnostic process has cancer.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>cancer diagnosis</obo:IAO_0000118>
<obo:IAO_0000119>OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>diagnosis of cancer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002372 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002372">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000015"/>
<obo:IAO_0000111>family clinical history of cancer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A clinical history in which there is a diagnosis of cancer in a blood relative.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>family history of cancer</obo:IAO_0000118>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>family clinical history of cancer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002373 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002373">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002372"/>
<obo:IAO_0000111>aunt clinical history of cancer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A clinical history in which there is a diagnosis of cancer in the female sibling of a parent.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>aunt clinical history of cancer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002374 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002374">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002372"/>
<obo:IAO_0000111>brother clinical history of cancer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A clinical history in which there is a diagnosis of cancer in a male sibling.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>brother clinical history of cancer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002375 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002375">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002372"/>
<obo:IAO_0000111>daughter clinical history of cancer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A clinical history in which there is a diagnosis of cancer in a person's female child.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>daughter clinical history of cancer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002376 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002376">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002372"/>
<obo:IAO_0000111>father clinical history of cancer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A clinical history in which there is a diagnosis of cancer in a male parent.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>father clinical history of cancer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002377 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002377">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002372"/>
<obo:IAO_0000111>mother clinical history of cancer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A clinical history in which there is a diagnosis of cancer in a female parent.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>mother clinical history of cancer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002378 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002378">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002372"/>
<obo:IAO_0000111>sister clinical history of cancer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A clinical history in which there is a diagnosis of cancer in a female sibling.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>sister clinical history of cancer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002379 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002379">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002372"/>
<obo:IAO_0000111>son clinical history of cancer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A clinical history in which there is a diagnosis of cancer in a person's male child.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>son clinical history of cancer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002380 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002380">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002372"/>
<obo:IAO_0000111>uncle clinical history of cancer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A clinical history in which there is a diagnosis of cancer in a male sibling of a parent.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>uncle clinical history of cancer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002381 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002381">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002372"/>
<obo:IAO_0000111>grandmother clinical history of cancer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A clinical history in which there is a diagnosis of cancer in a female parent of a parent.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>grandmother clinical history of cancer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002382 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002382">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002372"/>
<obo:IAO_0000111>grandfather clinical history of cancer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A clinical history in which there is a diagnosis of cancer in a male parent of a parent.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>grandfather clinical history of cancer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002383 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002383">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002372"/>
<obo:IAO_0000111>nephew clinical history of cancer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A clinical history in which there is a diagnosis of cancer in a male child of a sibling.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>nephew clinical history of cancer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002384 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002384">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002372"/>
<obo:IAO_0000111>niece clinical history of cancer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A clinical history in which there is a diagnosis of cancer in a female child of a sibling.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>niece clinical history of cancer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002385 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002385">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000073"/>
<obo:IAO_0000111>diagnosis of infectious disease</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A diagnosis that is an assertion that a patient who is the subject of a diagnostic process has an infectious disease.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>diagnosis of infectious disease</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002386 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002386">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002385"/>
<obo:IAO_0000111>diagnosis of hepatitis B</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A diagnosis of infectious disease caused by the hepatitis B virus.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>diagnosis of hepatitis B</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002387 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002387">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002385"/>
<obo:IAO_0000111>diagnosis of hepatitis C</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A diagnosis of infectious disease caused by the hepatitis C virus.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>diagnosis of hepatitis C</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002388 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002388">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002385"/>
<obo:IAO_0000111>diagnosis of HIV</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A diagnosis of infectious disease caused by the human immunodeficiency virus (1 or 2).</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>diagnosis of HIV</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002389 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002389">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000015"/>
<obo:IAO_0000111>clinical history of repeated HIV assays</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A clinical history in which there is repeated reactive screening assays for human immunodeficiency virus (1 or 2) antibodies regardless of the results of supplemental assays.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>clinical history of repeated HIV assays</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002390 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002390">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000015"/>
<obo:IAO_0000111>exposure to second hand smoke</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A clinical history in which there has been second hand exposure to tobacco smoking.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>exposure to second hand smoke</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002391 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002391">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002390"/>
<obo:IAO_0000111>exposure to second hand smoke in household during childhood</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An exposure to second hand smoke that occurred in the (patient's) household when the person was a child.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>exposure to second hand smoke in household during childhood</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002392 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002392">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002390"/>
<obo:IAO_0000111>exposure to second hand smoke in current household</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An exposure to second hand smoke in person's current household.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>exposure to second hand smoke in current household</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002393 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002393">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000015"/>
<obo:IAO_0000111>pregnancy history</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A clinical history in which a female has had a pregnancy.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pregnancy history</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002394 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002394">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
<obo:IAO_0000111>number of pregnancies</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A measurement datum of the total number of pregnancies a woman has had.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>number of pregnancies</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002395 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002395">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
<obo:IAO_0000111>number of live births</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A measurement datum of the total number of live births a female has had.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>number of live births</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002396 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002396">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001167"/>
<obo:IAO_0000111>age when gave birth to first child</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An age measurement datum performed on a female when her first biological child was born.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>age when gave birth to first child</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002397 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002397">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000015"/>
<obo:IAO_0000111>gynecologic surgery history</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A clinical history in which a woman has had gynecologic surgery in the past.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>gynecologic surgery history</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002398 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002398">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002397"/>
<obo:IAO_0000111>hysterectomy history</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A gynecologic surgery history in which a woman has had a hysterectomy.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>hysterectomy history</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002399 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002399">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002397"/>
<obo:IAO_0000111>unilateral oophorectomy history</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A gynecologic surgery history in which a woman has had a unilateral oophorectomy.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>unilateral oophorectomy history</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002400 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002400">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002397"/>
<obo:IAO_0000111>neither hysterectomy nor oophorectomy history</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A gynecologic surgery history in which a woman has not had either a hysterectomy or an oophorectomy.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>neither hysterectomy nor oophorectomy history</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002401 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002401">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
<obo:IAO_0000111>hormonal birth control use history</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An information content entity that indicates whether a woman has ever used oral contraceptives in order to block ovulation and prevent the occurrence of pregnancy.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>hormonal birth control use history</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002402 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002402">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002401"/>
<obo:IAO_0000111>hormonal birth control former use history</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A hormonal birth control use history that indicates an individual has previously been a hormonal birth control user but is not a current user.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>hormonal birth control former use history</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002403 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002403">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002401"/>
<obo:IAO_0000111>hormonal birth control current use history</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A hormonal birth control use history that indicates an individual is currently a hormonal birth control user.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>hormonal birth control current use history</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002404 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002404">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002401"/>
<obo:IAO_0000111>no hormonal birth control use history</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A hormonal birth control use history that indicates an individual has not ever been a hormonal birth control user.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>no hormonal birth control use history</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002405 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002405">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000015"/>
<obo:IAO_0000111>hormonal replacement therapy history</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A clinical history in which an individual has had hormonal replacement therapy in the past.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>hormonal replacement therapy history</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002406 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002406">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<obo:IAO_0000111>delivery form for hormonal replacement therapy</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A processed material used for delivery of hormones in hormone replacement therapy.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>form of hormone replacement therapy</obo:IAO_0000118>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>delivery form for hormonal replacement therapy</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002407 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002407">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002406"/>
<obo:IAO_0000111>pill delivery form for hormonal replacement therapy</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A delivery form for hormonal replacement therapy that is a pill for oral administration.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pill delivery form for hormonal replacement therapy</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002408 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002408">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002406"/>
<obo:IAO_0000111>patch delivery form for hormonal replacement therapy</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A delivery form for hormonal replacement therapy that is a patch for transdermal administration.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>patch delivery form for hormonal replacement therapy</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002409 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002409">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002406"/>
<obo:IAO_0000111>cream delivery form for hormonal replacement therapy</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A delivery form for hormonal replacement therapy that is a cream for transdermal administration.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>cream delivery form for hormonal replacement therapy</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002410 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002410">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
<obo:IAO_0000111>menopausal status</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An information content entity that indicates the state of a female's cessation of menstruation.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>menopausal status</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002411 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002411">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002410"/>
<obo:IAO_0000111>indeterminate menopausal status</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A menopausal status that is neither pre- nor post-menopausal.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>indeterminate menopausal status</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002412 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002412">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002410"/>
<obo:IAO_0000111>premenopausal status</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A menopausal status indicating that less than 6 months has passed since the last menstrual period and there has not been prior bilateral oophorectomy and not on estrogen replacement.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>premenopausal status</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002413 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002413">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002410"/>
<obo:IAO_0000111>perimenopausal status</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A menopausal status indicating that it has been 6-12 months since last menstrual period.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>perimenopausal status</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002414 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002414">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002410"/>
<obo:IAO_0000111>postmenopausal status</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A menopausal status indicating that it has been more than 12 months since the last menstrual period with no prior hysterectomy or that there has been a prior bilateral oophorectomy.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>postmenopausal status</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002415 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002415">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
<obo:IAO_0000111>exposure to environmental and workplace carcinogens history</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An information content entity that indicates the exposure of an individual to carcinogens in the workplace or environment.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>exposure to environmental and workplace carcinogens history</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002416 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002416">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002415"/>
<obo:IAO_0000111>exposure to arsenic history</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An exposure to environmental and workplace carcinogens history where the carcinogen is arsenic.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>exposure to arsenic history</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002417 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002417">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002415"/>
<obo:IAO_0000111>exposure to asbestos history</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An exposure to environmental and workplace carcinogens history where the carcinogen is asbestos.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>exposure to asbestos history</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002418 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002418">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002415"/>
<obo:IAO_0000111>exposure to diesel exhaust history</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An exposure to environmental and workplace carcinogens history where the carcinogen is diesel exhaust.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>exposure to diesel exhaust history</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002419 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002419">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002415"/>
<obo:IAO_0000111>exposure to chromium history</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An exposure to environmental and workplace carcinogens history where the carcinogen is chromium.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>exposure to chromium history</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002420 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002420">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002415"/>
<obo:IAO_0000111>exposure to silica history</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An exposure to environmental and workplace carcinogens history where the carcinogen is silica.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>exposure to silica history</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002421 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002421">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
<obo:IAO_0000111>indicator of whether an inclusion criterion was met</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An information content entity that indicates whether or not an entity has met a specific requirement in order to take part in a given process.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>eligibility criterion met</obo:IAO_0000118>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>indicator of whether an inclusion criterion was met</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002422 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002422">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
<obo:IAO_0000111>indicator of whether all inclusion criteria were met</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An information content entity that indicates whether or not an entity has met all specific requirements in order to take part in a given process.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>all eligibility criteria met</obo:IAO_0000118>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>indicator of whether all inclusion criteria were met</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002423 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002423">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500027"/>
<obo:IAO_0000111>age of majority inclusion criterion</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An inclusion criterion that uses the age of majority for a state or institution, where one is generally considered to be an adult, which if met, makes an individual suitable for a given task or participation in a given process.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>age of majority inclusion criterion</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002424 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002424">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500028"/>
<obo:IAO_0000111>chemotherapy treatment exclusion criterion</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An exclusion criterion that defines whether chemotherapy was received or is being received for a previous or current cancer, which when met, makes an individual unsuitable for a given task or participation in a given process</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>chemotherapy treatment exclusion criterion</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002425 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002425">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500028"/>
<obo:IAO_0000111>radiation treatment exclusion criteria</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An exclusion criterion that defines whether radiation was received or is being received for a previous or current cancer, which when met, makes an individual unsuitable for a given task or participation in a given process</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>radiation treatment exclusion criteria</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002426 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002426">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500028"/>
<obo:IAO_0000111>chemotherapy treatment within the recent past exclusion criterion</obo:IAO_0000111>
<obo:IAO_0000112>An exclusion criterion defined by the pathologist is defined as whether the individual received chemotherapy within the last two years.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An exclusion criterion that defines whether chemotherapy was received within a certain timeframe, which when met, makes an individual unsuitable for a given task or participation in a given process.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>chemotherapy treatment within the recent past exclusion criterion</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002427 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002427">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500028"/>
<obo:IAO_0000111>radiation treatment within the recent past exclusion criterion</obo:IAO_0000111>
<obo:IAO_0000112>An exclusion criterion defined by the pathologist is defined as whether the individual received radiation therapy within the last two years.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An exclusion criterion that defines whether radiation was received within a certain timeframe, which when met, makes an individual unsuitable for a given task or participation in a given process.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>radiation treatment within the recent past exclusion criterion</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002428 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002428">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500027"/>
<obo:IAO_0000111>BMI range inclusion criterion</obo:IAO_0000111>
<obo:IAO_0000112>An important inclusion criterion is for for the individual to have a BMI between 18.5 and 35.0</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An inclusion criterion that defines and states a Body Mass Index range, which if met, makes an individual suitable for a given task or participation in a given process.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>BMI range inclusion criterion</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002429 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002429">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500028"/>
<obo:IAO_0000111>blood transfusion exclusion criterion</obo:IAO_0000111>
<obo:IAO_0000112>An exclusion criterion that is defined by whether the specimen donor received a whole blood transfusion within 48 hours prior to death.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An exclusion criterion that is defined by whether the specimen donor received a whole blood transfusion within a specified time frame prior to death, which if met, makes a specimen donor unsuitable for a given task or participation in a given process.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>blood transfusion exclusion criterion</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002430 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002430">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500028"/>
<obo:IAO_0000111>history of metastatic cancer exclusion criterion</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An exclusion criterion defined as whether an individual has ever been diagnosed with metastatic cancer (cancer that spread beyond the initial site such as to other organs like brain bone or liver), which if met, makes the individual unsuitable for a given task or participation in a given process.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>history of metastatic cancer exclusion criterion</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002431 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002431">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500028"/>
<obo:IAO_0000111>intravenous drug use exclusion criterion</obo:IAO_0000111>
<obo:IAO_0000112>Donor eligibility based on history of intravenous drug abuse in the last 5 years.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An exclusion criterion defined as when an individual has a history of intravenous drug abuse for a specific timeframe, which if met, makes the individual unsuitable for a given task or participation in a given process.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>intravenous drug use exclusion criterion</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002432 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002432">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500028"/>
<obo:IAO_0000111>history of sex with someone with a history of blood borne infection exclusion criterion</obo:IAO_0000111>
<obo:IAO_0000112>Donor eligibility based on whether the donor has a history of sex with someone who has been diagnosed or at risk for HIV/AIDS and/or HCV and/or HBV in the last 5 years.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An exclusion criterion defined as whether an individual has a history of sex with someone who has been diagnosed or at risk for a blood borne infections disease in a specified time frame, which if met, makes the individual unsuitable for a given task or participation in a given process.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>history of sex with someone with a history of blood borne infection exclusion criterion</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002433 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002433">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500028"/>
<obo:IAO_0000111>history of sex with someone with a history of intravenous drugs exclusion criterion</obo:IAO_0000111>
<obo:IAO_0000112>Donor eligibility based on whether the donor has a history of sex with someone who has used intravenous drugs in the last 5 years.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An exclusion criterion defined as whether an individual has a history of sex with someone who has used intravenous drugs in a specified time frame, which if met, makes the individual unsuitable for a given task or participation in a given process.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>history of sex with someone with a history of intravenous drugs exclusion criterion</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002434 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002434">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500028"/>
<obo:IAO_0000111>HIV exclusion criterion</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An exclusion criterion defined as whether an individual has a history of repeatedly reactive screening assays for HIV-1 or HIV-2 antibody regardless of the results of supplemental assays, which if met, makes the individual unsuitable for a given task or participation in a given process.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>HIV exclusion criterion</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002435 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002435">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500028"/>
<obo:IAO_0000111>exposure to blood borne infectious disease exclusion criterion</obo:IAO_0000111>
<obo:IAO_0000112>Donor eligibility based on whether the donor has been exposed to HIV/AIDS.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An exclusion criterion defined as whether an individual has been exposed to a blood borne infections disease through needle sticks and/or contact with non-intact skin and/or contact with open wounds and/or contact with mucous membranes, which if met, makes the individual unsuitable for a given task or participation in a given process.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBIB</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>exposure to blood borne infectious disease exclusion criterion</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002436 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002436">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000470"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003368"/>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>RNA interactome capture</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that identifies RNA binding proteins by cross-linking RNA and proteins with UV light, then purifying the bound complexes by oligo(dT) capture. Finally, the complexes are analyzed by mass spectrometry.</obo:IAO_0000115>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000119>PMID:26463381</obo:IAO_0000119>
<rdfs:label>RNA interactome capture</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002437 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002437">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHMO_0000087"/>
<obo:IAO_0000111>widefield microscopy assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A fluorescence microscopy technique where the specimen under investigation is fully bathed in light, as opposed to confocal microscopy in which only a small portion of the specimen is illuminated.</obo:IAO_0000115>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000118>WFM</obo:IAO_0000118>
<obo:IAO_0000119>url:http://bitesizebio.com/19409/the-many-flavors-of-widefield-microscopy/</obo:IAO_0000119>
<obo:IAO_0000119>url:https://svi.nl/WideFieldMicroscope</obo:IAO_0000119>
<rdfs:label>widefield microscopy assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002438 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002438">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000023089"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001398"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>nuclear ligation assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that detects the proximity of chromosomal DNA through the use of a ligation reaction in isolated nuclei.</obo:IAO_0000115>
<obo:IAO_0000117>Chris S</obo:IAO_0000117>
<obo:IAO_0000119>PMID:8327891</obo:IAO_0000119>
<rdfs:label>nuclear ligation assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002439 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002439">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002438"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001917"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>chromosome conformation capture assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A nuclear ligation assay that detects chromosomal interactions between any two genomic loci. Chromatin segments are cross-linked, cut by restriction enzymes, ligated, and finally analyzed by PCR.</obo:IAO_0000115>
<obo:IAO_0000117>Chris S</obo:IAO_0000117>
<obo:IAO_0000118>3C assay</obo:IAO_0000118>
<obo:IAO_0000119>PMID:11847345</obo:IAO_0000119>
<obo:IAO_0000119>url:http://www.nature.com/nprot/journal/v2/n7/full/nprot.2007.243.html</obo:IAO_0000119>
<rdfs:label>chromosome conformation capture assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002440 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002440">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002439"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000626"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003368"/>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>Hi-C assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A chromosome conformation capture assay that detects genome-wide chromosomal interactions. High-throughput techniques are used to sequence the ligated fragments after cross-linking and cutting with restriction enzymes.</obo:IAO_0000115>
<obo:IAO_0000117>Chris S</obo:IAO_0000117>
<obo:IAO_0000119>PMID:20461051</obo:IAO_0000119>
<rdfs:label>Hi-C assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002441 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002441">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>physical examination of an organism</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An assay that produces a description of the qualities of an organism that has not been transformed, through observation and physical, non-invasive techniques.</obo:IAO_0000115>
<rdfs:label>physical examination of an organism</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002442 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002442">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002162"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000086"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_61073"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_61073"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>hydroxyl-radical footprinting assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A footprinting assay that uses the reaction of hydroxyl radicals with side-chain sites in molecules (proteins, DNA, etc)_ with the resultant mass shift demonstrating the site of modification, used to_ to asses the accessibility of that site.</obo:IAO_0000115>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>PMID:21770468</obo:IAO_0000119>
<rdfs:label>hydroxyl-radical footprinting assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002443 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002443">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002162"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001051"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001051"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000086"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_59056"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_59056"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001181"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>methidiumpropyl-EDTA-iron(II) footprinting assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A footprinting assay that determines protein-binding sites on DNA by partial cleavage of ligand-protected DNA restriction fragments with methidium-propyl-EDTA (MPE). MPE-Fe(II) in the presence of oxygen efficiently catalyzes the non-specific clevage of DNA.</obo:IAO_0000115>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000118>MPE-Fe(II) footprinting</obo:IAO_0000118>
<obo:IAO_0000119>PMID:6225070</obo:IAO_0000119>
<obo:IAO_0000119>PMID:6435669</obo:IAO_0000119>
<rdfs:label>methidiumpropyl-EDTA-iron(II) footprinting assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002444 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002444">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">measurand role</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A role borne by a material entity and realized in an assay which achieves the objective to measure the magnitude/concentration/amount of the measurand in the entity bearing evaluant role.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Alan Ruttenberg, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>https://en.wiktionary.org/wiki/measurand</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/778</obo:IAO_0000233>
<rdfs:label xml:lang="en">measurand role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002445 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002445">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000424"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000880"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000973"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0010467"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001851"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>transcription start site mapping by primer extension assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A transcription profiling assay in which the transcription start site for a gene is determined by identifying the 5' end of mRNA. A radio-labeled primer is annealed to a complementary mRNA sequence near the 3' end, then cDNA is synthesized until the 5' end is reached.</obo:IAO_0000115>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000119>PMID:23378648</obo:IAO_0000119>
<obo:IAO_0000119>url:https://en.wikipedia.org/wiki/Primer_extension</obo:IAO_0000119>
<rdfs:label>transcription start site mapping by primer extension assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002446 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002446">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
<obo:IAO_0000111>proteomic profiling design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design in which proteins in a sample are detected, quantified or otherwise analysed.</obo:IAO_0000115>
<obo:IAO_0000117>Dan Berrios</obo:IAO_0000117>
<obo:IAO_0000119>OBI:0001441</obo:IAO_0000119>
<rdfs:label>proteomic profiling design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002447 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002447">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000253"/>
<obo:IAO_0000111>suppression subtractive hybridization</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An artificially induced nucleic acid hybridization that is performed to compare gene expression in different cell or tissue types based on normalization and suppression, which creates a subtracted cDNA or genomic DNA library.</obo:IAO_0000115>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000118>SSH</obo:IAO_0000118>
<obo:IAO_0000118>subtractive hybridization</obo:IAO_0000118>
<obo:IAO_0000119>PMID:14970460</obo:IAO_0000119>
<rdfs:label>suppression subtractive hybridization</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002448 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002448">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000253"/>
<obo:IAO_0000111>differential screening hybridization</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An artificially induced nucleic acid hybridization that is performed to identify differentially expressed genes through hybridization of cDNA probes.</obo:IAO_0000115>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000118>DSH</obo:IAO_0000118>
<obo:IAO_0000118>differential screening</obo:IAO_0000118>
<obo:IAO_0000119>PMID:25472628</obo:IAO_0000119>
<rdfs:label>differential screening hybridization</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002449 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002449">
<owl:equivalentClass>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002162"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0003141"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001702"/>
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</owl:someValuesFrom>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001703"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002162"/>
<obo:IAO_0000111>footprinting assay measuring binding of a B cell epitope:antibody complex</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A footprinting assay that detects the binding of an antigen with an antibody.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, James Overton, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>qualitative binding|footprinting assay</obo:OBI_9991118>
<rdfs:label>footprinting assay measuring binding of a B cell epitope:antibody complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002450 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002450">
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002442"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0003141"/>
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<owl:Restriction>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001702"/>
</owl:Restriction>
</owl:someValuesFrom>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002442"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002449"/>
<obo:IAO_0000111>hydroxyl-radical footprinting assay measuring binding of a B cell epitope:antibody complex</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A hydroxyl-radical footprinting assay that detects the binding of an antigen with an antibody.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, James Overton, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>qualitative binding|hydroxyl-radical footprinting assay</obo:OBI_9991118>
<rdfs:label>hydroxyl-radical footprinting assay measuring binding of a B cell epitope:antibody complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002451 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002451">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000661"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0032607"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000661"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002452"/>
<obo:IAO_0000111>ELISA measuring epitope specific interferon-alpha production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An enzyme-linked immunosorbent assay that detects interferon-alpha production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>IFNa release|ELISA</obo:OBI_9991118>
<rdfs:label>ELISA measuring epitope specific interferon-alpha production by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002452 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002452">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0032607"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110129"/>
<obo:IAO_0000111>assay measuring epitope specific interferon-alpha production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A T cell epitope specific cytokine production assay that detects interferon-alpha production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>IFNa release|biological activity</obo:OBI_9991118>
<rdfs:label>assay measuring epitope specific interferon-alpha production by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002453 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002453">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500027"/>
<obo:IAO_0000111 xml:lang="en">health status inclusion criterion</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">‘diagnosed with Type 2 diabetes mellitus’, ‘E11.4’, ’not finding of hypertension'</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An inclusion criterion that defines and states one or more clinically significant bodily components, dispositions, and/or bodily processes of an entity that are inferred from relevant clinical findings or self-reported, which, if met, makes the entity suitable for a given task or participation in a given process.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Mathias Brochhausen</obo:IAO_0000117>
<obo:IAO_0000234 xml:lang="en">MIABIS2.0</obo:IAO_0000234>
<rdfs:label xml:lang="en">health status inclusion criterion</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002454 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002454">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500027"/>
<obo:IAO_0000111 xml:lang="en">clinically relevant lifestyle inclusion criterion</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">'smoking behavior’</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An inclusion criterion that defines and states one or more clinically relevant planned processes that a human being actively participates in , which, if met, makes the human being suitable for a given task or participation in a given process.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Mathias Brochhausen</obo:IAO_0000117>
<obo:IAO_0000234 xml:lang="en">MIABIS2.0</obo:IAO_0000234>
<rdfs:label xml:lang="en">clinically relevant lifestyle inclusion criterion</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002455 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002455">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500027"/>
<obo:IAO_0000111 xml:lang="en">clinically relevant exposure inclusion criterion</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">'exposure to cigarette smoke’, ‘exposure to lead through drinking water'</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An inclusion criterion that defines and states one or more clinically relevant histories of exposure of an entity, which, if met, makes the entity suitable for a given task or participation in a given process.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Mathias Brochhausen</obo:IAO_0000117>
<obo:IAO_0000234 xml:lang="en">MIABIS2.0</obo:IAO_0000234>
<rdfs:label xml:lang="en">clinically relevant exposure inclusion criterion</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002456 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002456">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500027"/>
<obo:IAO_0000111 xml:lang="en">gravidity inclusion criterion</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">'pregnant’, ‘not pregnant'</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An inclusion criterion that defines and states one or more gravidity statuses of an organism, which, if met, makes the entity suitable for a given task or participation in a given process.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Mathias Brochhausen</obo:IAO_0000117>
<obo:IAO_0000234 xml:lang="en">MIABIS2.0</obo:IAO_0000234>
<rdfs:label xml:lang="en">gravidity inclusion criterion</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002457 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002457">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001271"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002692"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000552"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>precision nuclear run-on sequencing assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An RNA-seq assay that maps the genome-wide distribution of transcriptionally-engaged Pol II at base-pair resolution by using biotin-labeled ribonucleotide triphosphate analogs (biotin-NTP) for nuclear run-on reactions, allowing the efficient affinity purification of nascent RNAs for high throughput sequencing from their 3' ends.</obo:IAO_0000115>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000118>PRO-Seq</obo:IAO_0000118>
<obo:IAO_0000118>precision nuclear run-on and sequencing assay</obo:IAO_0000118>
<obo:IAO_0000119>PMID:23430654</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/876</obo:IAO_0000233>
<rdfs:label>precision nuclear run-on sequencing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002458 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002458">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002438"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002692"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002598"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>chromosome conformation capture-on-chip assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A nuclear ligation assay which uses cross-linking of proteins to proteins and DNA, followed by two rounds of digestion and ligation, inverse PCR, and characterization by microarray or DNA sequencing. This enables unbiased genome-wide screens for DNA contacts made by single genomic sites of interest.</obo:IAO_0000115>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000118>4C assay</obo:IAO_0000118>
<obo:IAO_0000118>circularized chromosome conformation capture assay</obo:IAO_0000118>
<obo:IAO_0000119>url:http://www.sciencedirect.com/science/article/pii/B9780123919380000045</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/875</obo:IAO_0000233>
<rdfs:label>chromosome conformation capture-on-chip assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002459 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002459">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000435"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002440"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003368"/>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>genotype phasing by Hi-C assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A genotyping assay in which carbon-copy chromosome conformation is used to detect polymorphism in DNA samples.</obo:IAO_0000115>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000118>haplotype reconstruction by Hi-C assay</obo:IAO_0000118>
<obo:IAO_0000119>PMID:19815776</obo:IAO_0000119>
<obo:IAO_0000119>url:https://www.nature.com/articles/nbt.2728</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/828</obo:IAO_0000233>
<rdfs:label>genotype phasing by Hi-C assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002460 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002460">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500027"/>
<obo:IAO_0000111>defined population inclusion criterion</obo:IAO_0000111>
<obo:IAO_0000112>inclusion based on age, sex, and living region (rural area or specified city).</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An inclusion criterion that is based on fitting within the defined characteristics of a population based study design.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Mathias Brochhausen</obo:IAO_0000117>
<obo:IAO_0000119>MIABIS 2.0</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/920</obo:IAO_0000233>
<obo:IAO_0000234>MIABIS 2.0</obo:IAO_0000234>
<rdfs:label xml:lang="en">defined population inclusion criterion</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002461 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002461">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000098"/>
<obo:IAO_0000111 xml:lang="en">BCL format</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A data format specification that is a binary file containing base calling data. These files are created by sequencing machines during the act of sequencing, and contain data about each of the nucleotide clusters on a sequencing flow cell.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Stephen A. Fisher, Junhyong Kim, Dan Berrios</obo:IAO_0000117>
<rdfs:label xml:lang="en">BCL format</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002462 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002462">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000047"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001140"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>ERCC RNA spike-in</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A processed material developed by the External RNA Controls Consortium (ERCC) that consists of 92 transcripts, derived and traceable from NIST-certified DNA plasmids.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Stephen A. Fisher, Junhyong Kim, Dan Berrios</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">https://www.thermofisher.com/order/catalog/product/4456740</obo:IAO_0000119>
<rdfs:label>ERCC RNA spike-in</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002463 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002463">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000047"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001140"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">SIRV RNA spike-in</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A processed material that consists of transcript isoforms of 7 spike-in RNA variant (SIRV) genes and possibly the 92 External RNA Controls Consortium (ERCC) RNA spike-in genes.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Stephen A. Fisher, Junhyong Kim, Dan Berrios</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">https://www.lexogen.com/sirvs/design/</obo:IAO_0000119>
<rdfs:label xml:lang="en">SIRV RNA spike-in</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002464 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002464">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000577"/>
<obo:IAO_0000111 xml:lang="en">SRS identifier</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An accession number that applies to a database record for an individual sample object in an NCBI Sequence Read Archive (SRA) submission. These records are imported from the NCBI BioSample database.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Stephen Fisher, Dan Berrios</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">SRA sample accession number</obo:IAO_0000118>
<rdfs:label xml:lang="en">SRS identifier</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002465 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002465">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001167"/>
<obo:IAO_0000111 xml:lang="en">age since culture seeding measurement datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An age measurement datum that is the result of the measurement of the age of a cell since cultured (the process of seeding cells onto a culture dish).</obo:IAO_0000115>
<obo:IAO_0000117>Stephen A. Fisher, Junhyong Kim, Dan Berrios</obo:IAO_0000117>
<obo:IAO_0000118>age of culture</obo:IAO_0000118>
<rdfs:label>age since culture seeding measurement datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002466 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002466">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000064"/>
<obo:IAO_0000111 xml:lang="en">alignment counting algorithm</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An algorithm used to assign aligned sequence reads, resulting from a reference genome transcriptome alignment algorithm, to sequence features (e.g. genes or transcripts).</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Stephen A. Fisher, Junhyong Kim, Dan Berrios</obo:IAO_0000117>
<rdfs:label>alignment counting algorithm</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002467 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002467">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000594"/>
<obo:IAO_0000111 xml:lang="en">alignment counting application</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A software application that implements an alignment counting algorithm, used to count the overlap of aligned sequencing reads with genes.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Stephen A. Fisher, Junhyong Kim, Dan Berrios</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">doi:10.1093/bioinformatics/btu638</obo:IAO_0000119>
<rdfs:label xml:lang="en">alignment counting application</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002468 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002468">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000064"/>
<obo:IAO_0000111 xml:lang="en">base calling algorithm</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An algorithm that assigns nucleotides to temporal or spatial peaks generated by a detector, such as peaks of light intensities generated by a DNA sequencer</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Stephen A. Fisher, Junhyong Kim, Dan Berrios</obo:IAO_0000117>
<rdfs:label xml:lang="en">base calling algorithm</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002469 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002469">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000594"/>
<obo:IAO_0000111 xml:lang="en">base calling application</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A base-calling application that implments a base-calling algorithm to convert BCL (binary base call) files, (e.g., those generated by Illumina sequencing systems) to standard FASTQ file formats for downstream analysis.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Stephen A. Fisher, Junhyong Kim, Dan Berrios</obo:IAO_0000117>
<rdfs:label xml:lang="en">base calling application</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002470 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002470">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002469"/>
<obo:IAO_0000111 xml:lang="en">bcl2fastq software application</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A base calling application that implments a base calling algorithm to convert BCL (binary base call) files generated by Illumina sequencing systems to standard FASTQ file formats for downstream analysis.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Stephen A. Fisher, Junhyong Kim, Dan Berrios</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">https://support.illumina.com/sequencing/sequencing_software/bcl2fastq-conversion-software.html</obo:IAO_0000119>
<rdfs:label xml:lang="en">bcl2fastq software application</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002471 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002471">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
<obo:IAO_0000111 xml:lang="en">date process started</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A data item that is the date when a process was initiated.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Chris Stoeckert, Daniel Berrios, Stephen A. Fisher</obo:IAO_0000117>
<rdfs:label xml:lang="en">date process started</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002472 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002472">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000577"/>
<obo:IAO_0000111 xml:lang="en">dbGaP study identifier</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A central registered identifier symbol that denotes a specific study in dbGaP.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Stephen A. Fisher, Junhyong Kim, Dan Berrios</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">dbGaP accession number</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">doi:10.1038/ng1007-1181</obo:IAO_0000119>
<rdfs:label xml:lang="en">dbGaP study identifier</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002473 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002473">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000116"/>
<obo:IAO_0000111 xml:lang="en">material amplification role</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A worker role played by the person who runs the enzymatic amplifying process.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Stephen A. Fisher, Junhyong Kim, Dan Berrios</obo:IAO_0000117>
<rdfs:label xml:lang="en">material amplification role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002474 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002474">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000116"/>
<obo:IAO_0000111 xml:lang="en">material sequencing library preparation role</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A worker role played by the person who performs the library preparation process to generate a sequencing library for a sample to be sequenced.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Stephen A. Fisher, Junhyong Kim, Dan Berrios</obo:IAO_0000117>
<rdfs:label xml:lang="en">material sequencing library preparation role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002475 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002475">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
<obo:IAO_0000111 xml:lang="en">number of PCR cycles during library construction</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A data item that is the number of PCR cycles used during the construction of a sequencing library.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Stephen A. Fisher, Junhyong Kim, Dan Berrios</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">library construction PCR cycles</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">https://en.wikipedia.org/wiki/Polymerase_chain_reaction</obo:IAO_0000119>
<rdfs:label xml:lang="en">number of PCR cycles during library construction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002476 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002476">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
<obo:IAO_0000111 xml:lang="en">number of rounds of amplification</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A data item that is the number of times an amplification reaction happened.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Stephen A. Fisher, Junhyong Kim, Dan Berrios</obo:IAO_0000117>
<rdfs:label xml:lang="en">number of rounds of amplification</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002477 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002477">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000025"/>
<obo:IAO_0000111 xml:lang="en">reference genome role</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A reference substance role that is played by a reference genome when used during sequence alignment.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Stephen A. Fisher, Junhyong Kim, Dan Berrios</obo:IAO_0000117>
<rdfs:label xml:lang="en">reference genome role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002478 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002478">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000064"/>
<obo:IAO_0000111 xml:lang="en">reference genome-transcriptome alignment algorithm</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An algorithm that attempts to align a nucleic acid sequence to a reference genome and transcriptome.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Stephen A. Fisher, Junhyong Kim, Dan Berrios</obo:IAO_0000117>
<rdfs:label xml:lang="en">reference genome-transcriptome alignment algorithm</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002479 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002479">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
<obo:IAO_0000111 xml:lang="en">sequence read length measurement datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A measurement datum that is the result of the measurement of the number of bases in a DNA or RNA sequence.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Stephen A. Fisher, Junhyong Kim, Dan Berrios</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">read length, read length measurement datum</obo:IAO_0000118>
<rdfs:label xml:lang="en">sequence read length measurement datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002480 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002480">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000032"/>
<obo:IAO_0000111 xml:lang="en">sequencing library input quantity measurement datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A scalar measurement datum that indicates the amount of sequencing library used as input for a sequencer.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Stephen A. Fisher, Junhyong Kim</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">library input amount</obo:IAO_0000118>
<rdfs:label xml:lang="en">sequencing library input quantity measurement datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002481 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002481">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002754"/>
<obo:IAO_0000111 xml:lang="en">single-end library</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A cDNA library that is a collection of short tags from only one end of DNA fragments.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Stephen A. Fisher, Junhyong Kim, Dan Berrios</obo:IAO_0000117>
<rdfs:label xml:lang="en">single-end library</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002482 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002482">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
<obo:IAO_0000111 xml:lang="en">specimen harvest quantity</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A scalar measurement datum that indicates the amount of specimen collected.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Stephen A. Fisher, Junhyong Kim, Dan Berrios</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">harvest quantity</obo:IAO_0000118>
<rdfs:label xml:lang="en">specimen harvest quantity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002483 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002483">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
<obo:IAO_0000111 xml:lang="en">spike-in dilution factor</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A data item that indicates the dilution of spike-in added to a specimen.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Stephen A. Fisher, Junhyong Kim, Dan Berrios</obo:IAO_0000117>
<rdfs:label xml:lang="en">spike-in dilution factor</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002484 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002484">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002478"/>
<obo:IAO_0000111 xml:lang="en">star algorithm</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A reference genome transcriptome alignment algorithm that is a standalone RNA-seq alignment algorithm that uses uncompressed suffix arrays and a mapping algorithm similar to those used in large-scale genome alignment tools to align RNA-seq reads to a genomic reference.</obo:IAO_0000115>
<obo:IAO_0000119 xml:lang="en">Stephen A. Fisher, Junhyong Kim, Dan Berrios</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">https://www.ncbi.nlm.nih.gov/pubmed/23104886</obo:IAO_0000119>
<rdfs:label xml:lang="en">star algorithm</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002485 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002485">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600047"/>
<obo:IAO_0000111>transcript analysis by single-end sequencing assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A sequencing assay that incorporates single-end reads and sequencing technology to determine transcripts, gene structures, and gene expressions.</obo:IAO_0000115>
<obo:IAO_0000117>Dan Berrios</obo:IAO_0000117>
<obo:IAO_0000117>Junhyong Kim</obo:IAO_0000117>
<obo:IAO_0000117>Stephen A. Fisher</obo:IAO_0000117>
<obo:IAO_0000118>transcript analysis by single-end sequencing</obo:IAO_0000118>
<obo:IAO_0000119>url:https://www.illumina.com/science/technology/next-generation-sequencing/paired-end-vs-single-read-sequencing.html</obo:IAO_0000119>
<rdfs:label>transcript analysis by single-end sequencing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002486 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002486">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002466"/>
<obo:IAO_0000111 xml:lang="en">verse algorithm</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An alignment counting algorithm that assigns gene features to genomic alignments using a hierarchical assignment scheme, which allows simultaneous quantification of multiple feature types or annotation levels without repeatedly assigning reads.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Stephen A. Fisher, Junhyong Kim</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">http://kim.bio.upenn.edu/software/verse.shtml or http://biorxiv.org/content/early/2016/05/14/053306</obo:IAO_0000119>
<rdfs:label xml:lang="en">verse algorithm</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002487 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002487">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000932"/>
<obo:IAO_0000111>microraft</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A material separation device also commerically known as Isoraft, that is used to isolate single cells.</obo:IAO_0000115>
<obo:IAO_0000117>Stephen A. Fisher, Junhyong Kim, Dan Berrios</obo:IAO_0000117>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Microrafts</obo:IAO_0000119>
<rdfs:label>microraft</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002488 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002488">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<obo:IAO_0000111>pipette</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that is a laboratory tool commonly used in chemistry, biology and medicine to transport a measured volume of liquid, often as a media dispenser.</obo:IAO_0000115>
<obo:IAO_0000117>Stephen A. Fisher, Junhyong Kim, Dan Berrios</obo:IAO_0000117>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Pipette</obo:IAO_0000119>
<rdfs:label>pipette</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002489 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002489">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003498"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100051"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100051"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100051"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>differential medium assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An organism detection assay that uses a differential medium to achieve its objective.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>EuPathDB, https://www.uwyo.edu/molb2210_lab/info/biochemical_tests.htm</obo:IAO_0000119>
<rdfs:label>differential medium assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002490 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002490">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001931"/>
<obo:IAO_0000111>medication time value specification</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A scalar value specification that specifies the point in time that a human participant under investigation self-administers a medication material</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>medication timepoint</obo:IAO_0000118>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>medication time value specification</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002491 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002491">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001931"/>
<obo:IAO_0000111>medication dose value specification</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A scalar value specification that specifies the value of the quantity of a material entity administered to an organism as a treatment</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>medication dose</obo:IAO_0000118>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>medication dose value specification</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002492 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002492">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000097"/>
<obo:IAO_0000111 xml:lang="en">case role in case-control study</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A role that is borne by a case-control study design participant under investigation that is associated with the outcome mentioned in the study design.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">John Judkins, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">case role in case-control study</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002493 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002493">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000097"/>
<obo:IAO_0000111 xml:lang="en">control role in case-control study</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A role that is borne by a case-control study design participant under investigation that is not associated with the outcome mentioned in the study design.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">John Judkins, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">control role in case-control study</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002500 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002500">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_2000009"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000173"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2000009"/>
<obo:IAO_0000111>amniotic fluid specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from amniotic fluid.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, Penn Medicine Biobank</obo:IAO_0000119>
<rdfs:label>amniotic fluid specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002501 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002501">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002504"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001970"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002504"/>
<obo:IAO_0000111>bile specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from bile.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, Penn Medicine Biobank</obo:IAO_0000119>
<rdfs:label>bile specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002502 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002502">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_2000009"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001359"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2000009"/>
<obo:IAO_0000111>cerebrospinal fluid specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from cerbrospinal fluid.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, Penn Medicine Biobank</obo:IAO_0000119>
<rdfs:label>cerebrospinal fluid specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002503 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002503">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001988"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>feces specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from feces.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000118>stool specimen</obo:IAO_0000118>
<obo:IAO_0000119>Chris Stoeckert, Penn Medicine Biobank</obo:IAO_0000119>
<rdfs:label>feces specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002504 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002504">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_2000009"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0006911"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2000009"/>
<obo:IAO_0000111>digestive system fluid or secretion specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from digestive system fluid or secretion.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000118>gastric fluid specimen</obo:IAO_0000118>
<obo:IAO_0000119>Chris Stoeckert, Penn Medicine Biobank</obo:IAO_0000119>
<rdfs:label>digestive system fluid or secretion specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002505 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002505">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_2000009"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001913"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2000009"/>
<obo:IAO_0000111>milk specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from milk.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, Penn Medicine Biobank</obo:IAO_0000119>
<rdfs:label>milk specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002506 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002506">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_2000009"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002409"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2000009"/>
<obo:IAO_0000111>pericardial fluid specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from pericardial fluid.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, Penn Medicine Biobank</obo:IAO_0000119>
<rdfs:label>pericardial fluid specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002507 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002507">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_2000009"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001836"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2000009"/>
<obo:IAO_0000111>saliva specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from saliva.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, Penn Medicine Biobank</obo:IAO_0000119>
<rdfs:label>saliva specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002508 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002508">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_2000009"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0007311"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2000009"/>
<obo:IAO_0000111>sputum specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from sputum.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, Penn Medicine Biobank</obo:IAO_0000119>
<rdfs:label>sputum specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002509 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002509">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_2000009"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001089"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2000009"/>
<obo:IAO_0000111>sweat specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from sweat.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, Penn Medicine Biobank</obo:IAO_0000119>
<rdfs:label>sweat specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002510 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002510">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_2000009"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001090"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2000009"/>
<obo:IAO_0000111>synovial fluid specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from synovial fluid.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, Penn Medicine Biobank</obo:IAO_0000119>
<rdfs:label>synovial fluid specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002511 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002511">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_2000004"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001797"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2000004"/>
<obo:IAO_0000111>vitreous humor specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from vireous humor.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000118>vitreous fluid specimen</obo:IAO_0000118>
<obo:IAO_0000119>Chris Stoeckert, Penn Medicine Biobank</obo:IAO_0000119>
<rdfs:label>vitreous humor specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002512 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002512">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002371"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002662"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>bone marrow specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from bone marrow.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, Penn Medicine Biobank</obo:IAO_0000119>
<rdfs:label>bone marrow specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002513 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002513">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001987"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>placenta specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from placenta.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, Penn Medicine Biobank</obo:IAO_0000119>
<rdfs:label>placenta specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002514 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002514">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_2000009"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001268"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2000009"/>
<obo:IAO_0000111>peritoneal fluid specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from peritoneal fluid.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, Penn Medicine Biobank</obo:IAO_0000119>
<rdfs:label>peritoneal fluid specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002515 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002515">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_2000009"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001087"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2000009"/>
<obo:IAO_0000111>pleural fluid specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from pleural fluid.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, Penn Medicine Biobank</obo:IAO_0000119>
<rdfs:label>pleural fluid specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002516 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002516">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000955"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>brain specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from brain.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>brain specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002517 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002517">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001037"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>hair specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from hair.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>hair specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002518 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002518">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002367"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>prostate gland specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from prostate gland.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>prostate gland specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002519 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002519">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001134"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>skeletal muscle tissue specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from skeletal muscle.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>skeletal muscle tissue specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002520 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002520">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000948"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>heart specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from heart.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>heart specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002521 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002521">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000362"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>renal medulla specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from renal medulla.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000118>kidney medulla specimen</obo:IAO_0000118>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>renal medulla specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002522 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002522">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002369"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>adrenal gland specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from adrenal gland.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>adrenal gland specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002523 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002523">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000310"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>breast specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from breast.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000118>mammary tissue specimen</obo:IAO_0000118>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>breast specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002524 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002524">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001255"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>urinary bladder specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from urinary bladder.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>urinary bladder specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002525 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002525">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0007610"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>tibial artery specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from tibial artery.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>tibial artery specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002526 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002526">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002097"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>skin of body specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from skin.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000118>skin specimen</obo:IAO_0000118>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>skin of body specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002527 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002527">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001264"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>pancreas specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from pancreas.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>pancreas specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002528 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002528">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003483"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000945"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003483"/>
<obo:IAO_0000111>stomach specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from stomach.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>stomach specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002529 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002529">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000007"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>pituitary gland specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from pituitary gland.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>pituitary gland specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002530 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002530">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001013"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>adipose tissue specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from adipose tissue.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>adipose tissue specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002531 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002531">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001225"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>cortex of kidney specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from cortex of kidney.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000118>kidney cortex specimen</obo:IAO_0000118>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>cortex of kidney specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002532 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002532">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003483"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002469"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003483"/>
<obo:IAO_0000111>esophagus mucosa specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from esophagus mucosa.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>esophagus mucosa specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002533 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002533">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003483"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001155"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003483"/>
<obo:IAO_0000111>colon specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from colon.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>colon specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002534 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002534">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002783"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002048"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002783"/>
<obo:IAO_0000111>lung specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from lung.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>lung specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002535 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002535">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003483"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0004648"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003483"/>
<obo:IAO_0000111>esophagus muscularis mucosa specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from esophagus muscularis mucosa.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000118>esophagus muscularis specimen</obo:IAO_0000118>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>esophagus muscularis mucosa specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002536 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002536">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002516"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000956"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002516"/>
<obo:IAO_0000111>cerebral cortex specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from cerebral cortex.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000118>brain cortex specimen</obo:IAO_0000118>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>cerebral cortex specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002537 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002537">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002046"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>thyroid gland specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from thyroid gland.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>thyroid gland specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002538 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002538">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002516"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002037"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002516"/>
<obo:IAO_0000111>cerebellum specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from cerebellum.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000118>brain cerebellum specimen</obo:IAO_0000118>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>cerebellum specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002539 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002539">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001323"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>tibial nerve specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from tibial nerve.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>tibial nerve specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002540 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002540">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001621"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>coronary artery specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from coronary artery.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>coronary artery specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002541 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002541">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002106"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>spleen specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from spleen.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>spleen specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002542 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002542">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000947"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>aorta specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from aorta.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>aorta specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002543 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002543">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0006618"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>atrial appendage specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from the atrium auricular region.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>atrial appendage specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002544 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002544">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003483"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0007650"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003483"/>
<obo:IAO_0000111>esophagogastric junction specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from the esophagogastric junction.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>esophagogastric junction specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002545 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002545">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003483"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002116"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003483"/>
<obo:IAO_0000111>ileum specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from ileum.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>ileum specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002546 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002546">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002107"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>liver specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from liver.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>liver specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002547 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002547">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001830"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>minor salivary gland specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from minor salivary gland.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>minor salivary gland specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002548 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002548">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0003688"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>omentum specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from omentum.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>omentum specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002549 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002549">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000992"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>ovary specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from female gonad.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>ovary specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002550 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002550">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003483"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001159"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003483"/>
<obo:IAO_0000111>sigmoid colon specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from sigmoid colon.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>sigmoid colon specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002551 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002551">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002526"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0036149"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002526"/>
<obo:IAO_0000111>suprapubic skin specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from suprapubic skin.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>suprapubic skin specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002552 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002552">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000473"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>testis specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from testis.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>testis specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002553 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002553">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000995"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>uterus specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from uterus.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>uterus specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002554 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002554">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000996"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>vagina specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from vagina.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, NCI BBRB</obo:IAO_0000119>
<rdfs:label>vagina specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002555 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002555">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500027"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002556"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002557"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">age group inclusion criterion</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">"18-33 years old"</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An inclusion criterion that defines and states an age bracket which, if met, makes an entity suitable for a given task or participation in a given process.</obo:IAO_0000115>
<obo:IAO_0000117>Mathias Brochhausen</obo:IAO_0000117>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/839</obo:IAO_0000233>
<rdfs:label xml:lang="en">age group inclusion criterion</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002556 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002556">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001933"/>
<obo:IAO_0000111 xml:lang="en">minimum age value specification</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A value specifcation that specifies the youngest age when specifying an age range.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Mathias Brochhausen</obo:IAO_0000117>
<rdfs:label xml:lang="en">minimum age value specification</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002557 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002557">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001933"/>
<obo:IAO_0000111 xml:lang="en">maximum age value specification</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A value specifcation that specifies the oldest age when specifying an age range.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Mathias Brochhausen</obo:IAO_0000117>
<rdfs:label xml:lang="en">maximum age value specification</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002558 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002558">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500027"/>
<obo:IAO_0000111 xml:lang="en">use of medication inclusion criterion</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">"received at least 2 days of vancomycin"</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An inclusion criterion that defines and states a a set of medications, which, if used by an entity, makes that entity suitable for a given task or participation in a given process.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Mathias Brochhausen</obo:IAO_0000117>
<obo:IAO_0000233 xml:lang="en">https://github.com/obi-ontology/obi/issues/840</obo:IAO_0000233>
<rdfs:label xml:lang="en">use of medication inclusion criterion</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002559 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002559">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500027"/>
<obo:IAO_0000111 xml:lang="en">hospital patient inclusion criterion</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">"included hospital patients"</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An inclusion criterion defines that a human being has to be a hospital patient to be suitable for a given task or participation in a given process.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Mathias Brochhausen</obo:IAO_0000117>
<rdfs:label xml:lang="en">hospital patient inclusion criterion</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002560 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002560">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500027"/>
<obo:IAO_0000111 xml:lang="en">family status inclusion criterion</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">"included married and unmarried patients", "included divorced individuals"</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An inclusion criterion that defines and states one or more family statuses, which, if met, makes a human being suitable for a given task or participation in a given process.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Mathias Brochhausen</obo:IAO_0000117>
<rdfs:label xml:lang="en">family status inclusion criterion</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002561 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002561">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500027"/>
<obo:IAO_0000111 xml:lang="en">sex inclusion criterion</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">"included males and females", "included male patients"</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An inclusion criterion that defines and states one or more sexes which, if met, makes an entity suitable for a given task or participation in a given process.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Mathias Brochhausen</obo:IAO_0000117>
<rdfs:label xml:lang="en">sex inclusion criterion</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002562 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002562">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500027"/>
<obo:IAO_0000111 xml:lang="en">country of residence inclusion criteria</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">"include US residents"</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An inclusion criterion that defines and states one or more countries of residence which, if met, makes a human being suitable for a given task or participation in a given process.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Mathias Brochhausen</obo:IAO_0000117>
<rdfs:label xml:lang="en">country of residence inclusion criteria</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002563 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002563">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500027"/>
<obo:IAO_0000111 xml:lang="en">ethnicity inclusion criterion</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">"include only Hispanic individuals"</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An inclusion criteria that defines and states one or more ethnicities which, if met, makes an entity suitable for a given task or participation in a given process.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Mathias Brochhausen</obo:IAO_0000117>
<rdfs:label xml:lang="en">ethnicity inclusion criterion</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002564 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002564">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600020"/>
<obo:IAO_0000111>histopathology assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A histological assay that is intended to check for the presence or level of a specific disease.</obo:IAO_0000115>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>histopathology assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002565 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002565">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002585"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002578"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002579"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>adapter-sequence trimming</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A data transformation in which adapter sequences at the end of a molecular sequence are cut (removed).</obo:IAO_0000115>
<obo:IAO_0000117>Dan Berrios</obo:IAO_0000117>
<obo:IAO_0000119>Dan Berrios</obo:IAO_0000119>
<rdfs:label>adapter-sequence trimming</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002566 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002566">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200000"/>
<obo:IAO_0000111>file merge</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A data transformation in which data contained in 2 or more files are merged into a single file.</obo:IAO_0000115>
<obo:IAO_0000117>Dan Berrios</obo:IAO_0000117>
<obo:IAO_0000119>Dan Berrios</obo:IAO_0000119>
<rdfs:label>file merge</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002567 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002567">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200187"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000973"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002580"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>sequence alignment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A data transformation in which one or more sequences (reads) are positioned on a reference sequence template (often a reference set of genes), according to the genetic base-pairing paradigm.</obo:IAO_0000115>
<obo:IAO_0000117>Dan Berrios</obo:IAO_0000117>
<obo:IAO_0000119>Dan Berrios</obo:IAO_0000119>
<rdfs:label>sequence alignment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002568 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002568">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200187"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002580"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002582"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>sequence data feature count tabulation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The counting of features (typically, genes) within aligned sequence data, and organization of these counts into one or more tables.</obo:IAO_0000115>
<obo:IAO_0000117>Dan Berrios</obo:IAO_0000117>
<obo:IAO_0000119>Dan Berrios</obo:IAO_0000119>
<rdfs:label>sequence data feature count tabulation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002569 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002569">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000973"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002585"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000973"/>
<obo:IAO_0000111>trimmed sequence data</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The results of a data transformation of sequence data in which (e.g., low quality) read bases are removed, to achieve some specific objective.</obo:IAO_0000115>
<obo:IAO_0000117>Dan Berrios</obo:IAO_0000117>
<obo:IAO_0000119>Dan Berrios</obo:IAO_0000119>
<rdfs:label>trimmed sequence data</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002570 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002570">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001865"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
<owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/OBI_0001860"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>nCounter Mouse miRNA Expression array</obo:IAO_0000111>
<obo:IAO_0000112>Kolbert, Christopher P., et al. "Multi-platform analysis of microRNA expression measurements in RNA from fresh frozen and FFPE tissues." PloS one 8.1 (2013): e52517. PMID:23382819</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000115 xml:lang="en">A mouse array which is manufacutred by NanoString Technologies. Built upon color-coded molecular barcodes technology, the array profiles miRNA with increased specificity and sensitivty than microarrays.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Venkat Malladi, Chris Stoeckert, Jie Zheng, Alan Ruttenberg. Mark A. Miller added based on http://purl.obolibrary.org/obo/OBI_0002013</obo:IAO_0000117>
<obo:IAO_0000119>https://www.nanostring.com/products/mirna-assays/mirna-panels</obo:IAO_0000119>
<rdfs:label>nCounter Mouse miRNA Expression array</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002571 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002571">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001271"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000869"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>polyA-selected RNA sequencing assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An RNA-seq assay to study transcriptomes through the enrichment of polyadenylated transcripts or removal of ribosomal RNA prior to high-throughput sequencing.</obo:IAO_0000115>
<obo:IAO_0000117>Jason Hilton</obo:IAO_0000117>
<obo:IAO_0000117>Mark A. Miller</obo:IAO_0000117>
<obo:IAO_0000118>mRNA-seq</obo:IAO_0000118>
<obo:IAO_0000119>url:https://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-15-419</obo:IAO_0000119>
<obo:IAO_0000234>ENCODE</obo:IAO_0000234>
<rdfs:label>polyA-selected RNA sequencing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002572 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002572">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001271"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002573"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>polyA-depleted RNA sequencing assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An RNA-seq assay to study non-polyadenylated transcripts, such as, but not exclusive to unspliced and circular isoforms, through the depletion of polyadenylated transcripts prior to high-throughput sequencing.</obo:IAO_0000115>
<obo:IAO_0000117>Jason Hilton</obo:IAO_0000117>
<obo:IAO_0000117>Mark A. Miller</obo:IAO_0000117>
<obo:IAO_0000118>polyA-depleted RNA-seq</obo:IAO_0000118>
<obo:IAO_0000119>url:http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0030733</obo:IAO_0000119>
<obo:IAO_0000119>url:http://www.tandfonline.com/doi/full/10.1080/15476286.2015.1110676</obo:IAO_0000119>
<obo:IAO_0000234>ENCODE</obo:IAO_0000234>
<rdfs:label>polyA-depleted RNA sequencing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002573 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002573">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000880"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002574"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000880"/>
<obo:IAO_0000111>polyA depleted RNA extract</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A RNA extract that is the output of an extraction process in which RNA molecules lacking poly A tails at thier 3' ends are purified.</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, based on http://purl.obolibrary.org/obo/OBI_0000869</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>UPenn Group</obo:IAO_0000119>
<rdfs:label>polyA depleted RNA extract</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002574 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002574">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0666666"/>
<obo:IAO_0000111>RNA extraction with polyA depletion</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A RNA extraction process in which only RNAs lacking a polyA tail are retained</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, based on OBI_0000848</obo:IAO_0000117>
<obo:IAO_0000119>UPenn Group</obo:IAO_0000119>
<dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2018-05-11T15:01:14Z</dc:date>
<rdfs:label>RNA extraction with polyA depletion</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002575 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002575">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001271"/>
<obo:IAO_0000111>isoform sequencing</obo:IAO_0000111>
<obo:IAO_0000112>Novel transcript forms were assessed by isoform sequencing.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A method for sequencing isoforms by enriching a cDNA library for full-length reads spanning entire transcript isoforms.</obo:IAO_0000115>
<obo:IAO_0000118>ISO-seq</obo:IAO_0000118>
<obo:IAO_0000119>url:http://www.pacb.com/blog/intro-to-iso-seq-method-full-leng/</obo:IAO_0000119>
<rdfs:label>isoform sequencing</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002578 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002578">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000973"/>
<obo:IAO_0000111>adapter sequence data</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Nucleotide sequences of molecules that are ligated to assay samples prior to sequencing of these samples; these sequences are provided by assay kit manufacturers and typically used to combine sequencing of multiple samples in one assay run.</obo:IAO_0000115>
<obo:IAO_0000117>Dan Berrios</obo:IAO_0000117>
<obo:IAO_0000119>Dan Berrios</obo:IAO_0000119>
<rdfs:label>adapter sequence data</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002579 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002579">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000973"/>
<obo:IAO_0000111>adapter-trimmed sequence data</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The results of a data transformation of sequence data in which reference subsequences corresponding to ligated library adapters are removed.</obo:IAO_0000115>
<obo:IAO_0000117>Dan Berrios</obo:IAO_0000117>
<obo:IAO_0000119>Dan Berrios</obo:IAO_0000119>
<rdfs:label>adapter-trimmed sequence data</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002580 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002580">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000973"/>
<obo:IAO_0000111>aligned sequence data</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The results of a sequence alignment.</obo:IAO_0000115>
<obo:IAO_0000117>Dan Berrios</obo:IAO_0000117>
<obo:IAO_0000119>Dan Berrios</obo:IAO_0000119>
<rdfs:label>aligned sequence data</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002581 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002581">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000973"/>
<rdfs:subClassOf>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002566"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>merged aligned sequence data</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The results of a data transformation of sequence data in which files containing aligned sequence data are merged together</obo:IAO_0000115>
<obo:IAO_0000117>Dan Berrios</obo:IAO_0000117>
<obo:IAO_0000119>Dan Berrios</obo:IAO_0000119>
<rdfs:label>merged aligned sequence data</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002582 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002582">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000100"/>
<obo:IAO_0000111>sequence library feature count data</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The results of a sequence data feature count tabulation.</obo:IAO_0000115>
<obo:IAO_0000117>Dan Berrios</obo:IAO_0000117>
<obo:IAO_0000119>Dan Berrios</obo:IAO_0000119>
<rdfs:label>sequence library feature count data</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002583 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002583">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000973"/>
<rdfs:subClassOf>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000634"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>DNA methylation profiling data</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">The results of a DNA methylation profiling assay</obo:IAO_0000115>
<rdfs:label>DNA methylation profiling data</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002584 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002584">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000100"/>
<obo:IAO_0000111>differential expression analysis data</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">The results of a differential expression analysis.</obo:IAO_0000115>
<rdfs:label>differential expression analysis data</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002585 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002585">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200000"/>
<obo:IAO_0000111>sequence trimming</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A data transformation in which subsequences of a molecular sequence are cut (removed).</obo:IAO_0000115>
<rdfs:label>sequence trimming</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002586 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002586">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000393"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>digital acquisition card</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The digital acquisition card acts as the interface between the computer and a measurement device via the computer bus. It converts the signal generated by a measurement device (output from device) to a digital signal via an analog-to-digital converter, ADC. It also converts a digital signal to an analog signal via a digital-to-analog converter, DAC. This analog signal (e.g., stimulus) is fed to a measurement device (input to device).</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller</obo:IAO_0000117>
<obo:IAO_0000118>DAQ device</obo:IAO_0000118>
<obo:IAO_0000118>digital acquisition and digital generation card</obo:IAO_0000118>
<obo:IAO_0000119>Brenda Farrell, bfarrell@bcm.edu</obo:IAO_0000119>
<rdfs:label>digital acquisition card</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002587 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002587">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<obo:IAO_0000111>machine learning</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A planned process with the objective to give a computer the ability to use patterns in data to progressively improve its performance on a specific task, achieved by using statistical techniques instead of explicitly programming the ability.</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller</obo:IAO_0000117>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Machine_learning</obo:IAO_0000119>
<dc:contributor>https://github.com/TrisSN</dc:contributor>
<rdfs:label>machine learning</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002588 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002588">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002587"/>
<obo:IAO_0000111>supervised machine learning</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A machine learning process using a function that maps an input to an output based on example input-output pairs. It infers a function from labeled training data consisting of a set of training examples.</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller</obo:IAO_0000117>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Supervised_learning</obo:IAO_0000119>
<dc:contributor>https://github.com/TrisSN</dc:contributor>
<rdfs:label>supervised machine learning</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002589 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002589">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002587"/>
<obo:IAO_0000111>unsupervised machine learning</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A machine learning process that infers a function describing the structure of "unlabeled" data (i.e. data that has not been classified or categorized).</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller</obo:IAO_0000117>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Unsupervised_learning</obo:IAO_0000119>
<dc:contributor>https://github.com/TrisSN</dc:contributor>
<rdfs:label>unsupervised machine learning</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002590 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002590">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000131"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>molecular interaction identification design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design that investigates the features of interaction between molecules.</obo:IAO_0000115>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000119>person:RCT</obo:IAO_0000119>
<rdfs:label>molecular interaction identification design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002591 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002591">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002590"/>
<obo:IAO_0000111>colocalization identification design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A molecular interaction identification design that investigates the co-occurence and correlation of two or more molecules.</obo:IAO_0000115>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000119>url:https://en.wikipedia.org/wiki/Colocalization</obo:IAO_0000119>
<rdfs:label>colocalization identification design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002592 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002592">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002590"/>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000750"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001404"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>genetic interaction identification design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A molecular interaction identification design that investigates a phenotype that is the result of two or more genetic perturbations, and is not explained by the individual genetic perturbations alone.</obo:IAO_0000115>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000119>MI:0208</obo:IAO_0000119>
<rdfs:label>genetic interaction identification design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002593 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002593">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002590"/>
<obo:IAO_0000111>functional association identification design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A molecular interaction identification design that investigates a relationship that is the result of intermediate steps between two or more molecules that are not necessarily in direct contact with each other.</obo:IAO_0000115>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000119>MI:2286</obo:IAO_0000119>
<rdfs:label>functional association identification design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002594 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002594">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002590"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000058"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001146"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
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<obo:IAO_0000111>direct interaction identification design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A molecular interaction identification design that investigates the influence of molecules, which are in direct contact, on one another.</obo:IAO_0000115>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000118>molecular binding identification design</obo:IAO_0000118>
<obo:IAO_0000119>MI:0407</obo:IAO_0000119>
<rdfs:label>direct interaction identification design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002595 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002595">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002594"/>
<obo:IAO_0000111>enzymatic reaction identification design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A direct interaction identification design that investigations a biological reaction on a molecule which has been triggered by an enzyme.</obo:IAO_0000115>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000119>MI:0414</obo:IAO_0000119>
<rdfs:label>enzymatic reaction identification design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002596 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002596">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002590"/>
<obo:IAO_0000111>self interaction identification design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A molecular interaction identification design that investigates intra-molecular interactions between two or more regions of a single molecule.</obo:IAO_0000115>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000119>MI:1126</obo:IAO_0000119>
<rdfs:label>self interaction identification design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002597 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002597">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002458"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600047"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001108"/>
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</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001108"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001010"/>
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</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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<owl:intersectionOf rdf:parseType="Collection">
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000973"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/SO_0000001"/>
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<obo:IAO_0000111>chromosome conformation capture sequencing assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A chromosome conformation capture-on-chip assay quantitates the products with multiplexed high-throughput sequencing.</obo:IAO_0000115>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000118>3C-seq assay</obo:IAO_0000118>
<obo:IAO_0000119>PMID:23411633</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/939</obo:IAO_0000233>
<rdfs:label>chromosome conformation capture sequencing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002598 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002598">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000415"/>
<obo:IAO_0000111>inverse polymerase chain reaction</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A polymerase chain reaction which amplifies DNA with only one known sequence from which primers may be designed. A series of restriction digestions and ligations result in a looped DNA fragment which can be primed for PCR.</obo:IAO_0000115>
<obo:IAO_0000117>Rebecca Tauber</obo:IAO_0000117>
<obo:IAO_0000118>inverse PCR</obo:IAO_0000118>
<obo:IAO_0000119>url:https://en.wikipedia.org/wiki/Chromosome_conformation_capture</obo:IAO_0000119>
<rdfs:label>inverse polymerase chain reaction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002599 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002599">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100051"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002600"/>
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</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0100051"/>
<obo:IAO_0000111>swab specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is stored on a swab as the output of a collecting specimen with swab process.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>OBIB/OBI</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/910</obo:IAO_0000233>
<obo:IAO_0000234>OBIB</obo:IAO_0000234>
<rdfs:label>swab specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002600 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002600">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
<obo:IAO_0000111>collecting specimen with swab</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen collection process that uses a swab as the collection device. A swab is an absorbent material (e.g. cotton) on a rod (e.g., wooden stick).</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>OBIB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/910</obo:IAO_0000233>
<obo:IAO_0000234>OBIB</obo:IAO_0000234>
<rdfs:label>collecting specimen with swab</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002601 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002601">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000973"/>
<obo:IAO_0000111>demultiplexed sequence data</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Sequence data in which an identifier subsequence has been used to categorize each reads by source.</obo:IAO_0000115>
<obo:IAO_0000117>Dan Berrios</obo:IAO_0000117>
<obo:IAO_0000119>Dan Berrios</obo:IAO_0000119>
<rdfs:label>demultiplexed sequence data</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002602 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002602">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000973"/>
<obo:IAO_0000111>multiplexed sequence data</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Sequence data from a sequence library generated from at least two different sources, where each read in the sequence data includes base calls from a multiplex identifier sequence that can be used to trace the source of the read to its source.</obo:IAO_0000115>
<obo:IAO_0000117>Dan Berrios</obo:IAO_0000117>
<obo:IAO_0000119>Dan Berrios</obo:IAO_0000119>
<rdfs:label>multiplexed sequence data</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002603 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002603">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002604"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002600"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000659"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002032"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002604"/>
<obo:IAO_0000111>areolar swab specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is collected with a swab from the surface of an areola of a breast.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, OBIB</obo:IAO_0000119>
<rdfs:label>areolar swab specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002604 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002604">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002523"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002600"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000659"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000310"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002523"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002599"/>
<obo:IAO_0000111>breast swab specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is collected with a swab from the surface of a breast.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, OBIB</obo:IAO_0000119>
<rdfs:label>breast swab specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002605 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002605">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002607"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002600"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000659"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001567"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002607"/>
<obo:IAO_0000111>cheek swab specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is collected with a swab from the cheek portion of the inside surface of a mouth.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, OBIB</obo:IAO_0000119>
<rdfs:label>cheek swab specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002606 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002606">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_2000007"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002600"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000659"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001728"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002599"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2000007"/>
<obo:IAO_0000111>nasopharyngeal swab specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is collected with a swab from the surface of a nasopharynx.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, OBIB</obo:IAO_0000119>
<rdfs:label>nasopharyngeal swab specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002607 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002607">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002600"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000659"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000165"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002599"/>
<obo:IAO_0000111>oral swab specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is collected with a swab from the inside surface of a mouth.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, OBIB</obo:IAO_0000119>
<rdfs:label>oral swab specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002608 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002608">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_2000006"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002600"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000659"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001729"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002599"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2000006"/>
<obo:IAO_0000111>oropharyngeal swab specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is collected with a swab from the surface of a oropharynx.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, OBIB</obo:IAO_0000119>
<rdfs:label>oropharyngeal swab specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002609 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002609">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003483"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002600"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000659"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001052"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002599"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003483"/>
<obo:IAO_0000111>rectal swab specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is collected with a swab from the surface of a rectum.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, OBIB</obo:IAO_0000119>
<rdfs:label>rectal swab specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002610 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002610">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002607"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002600"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000659"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001723"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002607"/>
<obo:IAO_0000111>tongue swab specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is collected with a swab from the surface of a tongue.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, OBIB</obo:IAO_0000119>
<rdfs:label>tongue swab specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002611 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002611">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002554"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002600"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000659"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000996"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002554"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002599"/>
<obo:IAO_0000111>vagina swab specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is collected with a swab from the surface of a vagina.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, OBIB</obo:IAO_0000119>
<rdfs:label>vagina swab specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002612 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002612">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002503"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002600"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000659"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001988"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002503"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002599"/>
<obo:IAO_0000111>fecal swab specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is collected with a swab from the surface of a feces.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000118>stool swab specimen</obo:IAO_0000118>
<obo:IAO_0000119>Chris Stoeckert, OBIB</obo:IAO_0000119>
<rdfs:label>fecal swab specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002613 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002613">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100051"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002600"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000659"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/ENVO_00010483"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002599"/>
<obo:IAO_0000111>environmental swab specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is collected with a swab from the surface of an environmenal material.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Chris Stoeckert, OBIB</obo:IAO_0000119>
<rdfs:label>environmental swab specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002614 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002614">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
<obo:IAO_0000111>birth cohort study design</obo:IAO_0000111>
<obo:IAO_0000112>The LucKi Birth Cohort Study was designed and started in 2006 to follow children from birth into adulthood on a wide range of determinants, disorders, and diseases.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cohort study design for which the subjects are followed from the time of birth usually including information about gestation and follow up.</obo:IAO_0000115>
<obo:IAO_0000117>MIABIS</obo:IAO_0000117>
<obo:IAO_0000119>MIABIS contributors</obo:IAO_0000119>
<rdfs:label>birth cohort study design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002615 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002615">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
<obo:IAO_0000111>disease specific study design</obo:IAO_0000111>
<obo:IAO_0000112>A study of the symptoms experienced by patients who have been diagnosed with multiple sclerosis employs a disease specific study design.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design for which material and information is collected from subjects that have already developed a particular disease.</obo:IAO_0000115>
<obo:IAO_0000117>MIABIS</obo:IAO_0000117>
<obo:IAO_0000119>MIABIS contributors</obo:IAO_0000119>
<rdfs:label>disease specific study design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002616 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002616">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000310"/>
<obo:IAO_0000111 xml:lang="en">genealogical record</obo:IAO_0000111>
<obo:IAO_0000112>A family tree is a type of genealogical record.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A document about the family relationships of persons related as members of a domestic group linked through descent from a common ancestor, marriage, or adoption.</obo:IAO_0000115>
<obo:IAO_0000117>MIABIS</obo:IAO_0000117>
<obo:IAO_0000117>Sarah Bost</obo:IAO_0000117>
<rdfs:label xml:lang="en">genealogical record</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002617 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002617">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
<obo:IAO_0000111 xml:lang="en">national registry</obo:IAO_0000111>
<obo:IAO_0000112>The Social Security Administration's Death Master File is a national registry in the United States.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An information content entity that contains information about a nationwide group of individuals.</obo:IAO_0000115>
<obo:IAO_0000117>MIABIS</obo:IAO_0000117>
<obo:IAO_0000117>Sarah Bost</obo:IAO_0000117>
<obo:IAO_0000119>MIABIS contributors</obo:IAO_0000119>
<rdfs:label xml:lang="en">national registry</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002618 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002618">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002617"/>
<obo:IAO_0000111 xml:lang="en">national biomedical registry</obo:IAO_0000111>
<obo:IAO_0000112>The Care Register for Health Care, maintained by the Finnish National Institute for Health and Welfare, is a national biomedical registry.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A national registry that contains information about individuals that was accumulated for a biomedical purpose, such as diagnoses, treatments, or outcomes.</obo:IAO_0000115>
<obo:IAO_0000117>MIABIS</obo:IAO_0000117>
<obo:IAO_0000117>Sarah Bost</obo:IAO_0000117>
<obo:IAO_0000119>MIABIS contributors</obo:IAO_0000119>
<rdfs:label xml:lang="en">national biomedical registry</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002619 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002619">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001154"/>
<obo:IAO_0000111>site-directed mutagenesis</obo:IAO_0000111>
<obo:IAO_0000112>Site-directed mutagenesis was used to prepare mutants of the Hypoxia-inducible factor-1 (HIF-1) alpha subunit to investigate the role of certain amino acids in hypoxia. (PMID:12393189)</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">An induced mutation in which a specific base change is programmed into the sequence of a synthetic primer.</obo:IAO_0000115>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000119>url:https://www.ncbi.nlm.nih.gov/books/NBK21945/</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1058</obo:IAO_0000233>
<rdfs:label>site-directed mutagenesis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002620 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002620">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001154"/>
<obo:IAO_0000111>random mutagenesis</obo:IAO_0000111>
<obo:IAO_0000112>Error-prone PCR was used to introduce amino acid mutations to the cAMP receptor protein (CRP) of E. coli to investigate strain engineering to improve osmotolerance for industrial requirements. (PMID:22179860)</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">An induced mutation that produces a random mutation, either by introducing the organism to mutagens, or through a process such as error-prone PCR.</obo:IAO_0000115>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000119>PMID:15153637</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1058</obo:IAO_0000233>
<rdfs:label>random mutagenesis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002621 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002621">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000471"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000059"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001285"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002590"/>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0009987"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>reconstitution assay</obo:IAO_0000111>
<obo:IAO_0000112>"In an attempt to define the mechanism of insulin-regulated glucose transporter 4 (Glut4) translocation, we have developed an in vitro reconstitution assay... insulin-induced Glut4 translocation can be reconstituted in vitro to a limited extent by using isolated membranes." (PMID:10611313)</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">An assay in which a cellular process is replicated from the bottom-up using isolated components in order to observe how the components work together.</obo:IAO_0000115>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000118>reconstitution experiment</obo:IAO_0000118>
<obo:IAO_0000119>url:https://jcs.biologists.org/content/132/4/jcs227488</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1059</obo:IAO_0000233>
<rdfs:label>reconstitution assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002622 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002622">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002621"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0001172"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>in vitro transcription reconstitution assay</obo:IAO_0000111>
<obo:IAO_0000112>An in vitro reconstituted mouse transcription system helped identify an NF-Y interacting promoter as essential for high-level expression from the R2 promoter. (PMID:11502214)</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A reconstitution assay in which RNA synthesis is investigated using RNA polymerase II transcription systems replicated in vitro from their base components.</obo:IAO_0000115>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000119>PMID:9237163</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1059</obo:IAO_0000233>
<rdfs:label>in vitro transcription reconstitution assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002623 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002623">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000626"/>
<obo:IAO_0000111>whole metagenome sequencing assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A DNA sequencing assay that intends to provide information on the DNA sequences of multiple genomes (a metagenome) from different organisms present in the same input sample.</obo:IAO_0000115>
<obo:IAO_0000116>Whole metagenome sequencing has been used to explore the composition and metabolic capability of communities of microbes found in the environment (e.g. in soil, water, etc.) and in humans and other species (e.g. in the gut, oral cavity, etc.).</obo:IAO_0000116>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000118>WMS</obo:IAO_0000118>
<obo:IAO_0000119>Bjoern Peters</obo:IAO_0000119>
<obo:IAO_0000119>Michelle Giglio</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1056</obo:IAO_0000233>
<rdfs:label>whole metagenome sequencing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002624 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002624">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
<obo:IAO_0000111>case-control study design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design that entails the creation of two types of roles, such that each participant under investigation bears one or the other. What distinguishes the two types of roles is an 'outcome', which is associated with participants that have the case role but not associated with participants that have the control role. A case-control study examines the hypothesis that the presence of the outcome in case participants is associated with an 'exposure' that is not associated with control participants.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>Wikipedia, OBI</obo:IAO_0000119>
<rdfs:label>case-control study design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002625 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002625">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600043"/>
<obo:IAO_0000111>gene knockdown</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A genetic transformation which reduces the expression of a specific gene or genes in an organism.</obo:IAO_0000115>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000118>gene knock-down</obo:IAO_0000118>
<obo:IAO_0000119>url:https://en.wikipedia.org/wiki/Gene_knockdown</obo:IAO_0000119>
<rdfs:label>gene knockdown</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002626 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002626">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002625"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001152"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>RNAi gene knockdown</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A gene knockdown that silences genes through artificially-induced RNA interference. This is accomplished by introducing small double-stranded interfering RNA complementary to the target mRNA to be silenced, which is then cleaved by a ribonuclease.</obo:IAO_0000115>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000118>RNA interference gene knockdown</obo:IAO_0000118>
<obo:IAO_0000119>url:https://en.wikipedia.org/wiki/Gene_knockdown</obo:IAO_0000119>
<rdfs:label>RNAi gene knockdown</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002627 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002627">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000880"/>
<obo:IAO_0000111>ribosomal RNA-depleted RNA extract</obo:IAO_0000111>
<obo:IAO_0000112>Looking at the reads for each ribosomal RNA-depleted RNA extract, the vast majority align to protein coding genes based on the ENSEMBL annotation.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">An extract of RNA which is produced through rRNA (ribosomal RNA) depletion (the removal of highly abundant rRNA species).</obo:IAO_0000115>
<obo:IAO_0000117>Dan Berrios</obo:IAO_0000117>
<obo:IAO_0000119>https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-018-4585-1</obo:IAO_0000119>
<rdfs:label>ribosomal RNA-depleted RNA extract</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002628 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002628">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001672"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002626"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>RNAi knockdown assay</obo:IAO_0000111>
<obo:IAO_0000112>"Here, we described the development of RNAi by micro-injection of double-stranded RNA (dsRNA) in the pea aphid Acyrthosiphon pisum. Injection of dsRNA into whole aphid body induced the silencing of two marker genes with different expression patterns: the ubiquitously expressed Ap-crt genes encoding a calreticulin and the gut specific Ap-cath-L gene encoding a cathepsin-L." (PMID:17903251)</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A gene knockdown assay in which RNAi gene knockdown is used to disrupt gene transcripts.</obo:IAO_0000115>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000118>RNA interference knockdown assay</obo:IAO_0000118>
<obo:IAO_0000118>RNAi gene knockdown assay</obo:IAO_0000118>
<obo:IAO_0000119>Rebecca Jackson</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1057</obo:IAO_0000233>
<rdfs:label>RNAi knockdown assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002629 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002629">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001177"/>
<obo:IAO_0000111>direct RNA sequencing assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">An assay to study transcription through direct RNA sequence determination, without prior conversion of RNA molecules to cDNA.</obo:IAO_0000115>
<obo:IAO_0000117>Dan Berrios</obo:IAO_0000117>
<obo:IAO_0000118>DRS</obo:IAO_0000118>
<obo:IAO_0000118>direct RNA-seq</obo:IAO_0000118>
<obo:IAO_0000119>url:https://www.nature.com/articles/nature08390</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/874</obo:IAO_0000233>
<obo:IAO_0000234>jahilton</obo:IAO_0000234>
<rdfs:label>direct RNA sequencing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002630 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002630">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003685"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
<owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/OBI_0000759"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>Illumina NovaSeq 6000</obo:IAO_0000111>
<obo:IAO_0000112>Genomic DNA of Xenophilus sp. E41 was extracted and sequenced using an Illumina NovaSeq 6000 system.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A DNA sequencer which is manufactured by the Illumina corporation, with two flow cells and an output of up to 6000 Gb (32-40 B reads per run). The sequencer utilizes synthesis technology and patterned flow cells to optimize throughput and even spacing of sequencing clusters.</obo:IAO_0000115>
<obo:IAO_0000117>Dan Berrios</obo:IAO_0000117>
<obo:IAO_0000118>NovaSeq 6000</obo:IAO_0000118>
<obo:IAO_0000119>http://www.illumina.com/systems/sequencing-platforms/novaseq.html</obo:IAO_0000119>
<rdfs:label>Illumina NovaSeq 6000</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002631 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002631">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001271"/>
<obo:IAO_0000111>single-cell RNA sequencing assay</obo:IAO_0000111>
<obo:IAO_0000112>Single-cell RNA sequencing (scRNA-seq) assays provide the expression profiles of individual cells.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">An RNA sequencing assay that uses RNA extracts as input that can be traced to a single cell of origin.</obo:IAO_0000115>
<obo:IAO_0000117>Dan Berrios</obo:IAO_0000117>
<obo:IAO_0000118>scRNA-seq</obo:IAO_0000118>
<obo:IAO_0000119>Anna Maria Masci</obo:IAO_0000119>
<rdfs:label>single-cell RNA sequencing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002632 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002632">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400103"/>
<obo:IAO_0000111>PacBio Sequel</obo:IAO_0000111>
<obo:IAO_0000112>The cDNAs were sequenced on the PacBio Sequel platform.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A DNA sequencer built upon single molecule real-time sequencing technology, optimized for generation with long reads and high consensus accuracy, and manufactured by the Pacific Biosciences corporation</obo:IAO_0000115>
<obo:IAO_0000117>Bonita Lam</obo:IAO_0000117>
<obo:IAO_0000117>Dan Berrios</obo:IAO_0000117>
<obo:IAO_0000118>Pacific BioSciences Sequel</obo:IAO_0000118>
<obo:IAO_0000119>http://www.pacb.com/products-and-services/pacbio-systems/sequel/</obo:IAO_0000119>
<rdfs:label>PacBio Sequel</rdfs:label>
</owl:Class>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400169"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
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</owl:someValuesFrom>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000185"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003368"/>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>Giemsa stain assay</obo:IAO_0000111>
<obo:IAO_0000112>Cytogenetics; the histopathological diagnosis of malaria and other parasites; differentiate nuclear and cytoplasmic morphology of the various blood cells like platelets, RBCs, WBCs</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that uses a Giemsa stain to characterize cells.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1093</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>Giemsa stain assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002648 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002648">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
<owl:qualifiedCardinality rdf:datatype="http://www.w3.org/2001/XMLSchema#nonNegativeInteger">1</owl:qualifiedCardinality>
<owl:onClass rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0100051"/>
<obo:IAO_0000111>individual organism specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen composed of an individual organism to be studied in an investigation.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>EFO_0000542 individual</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1092</obo:IAO_0000233>
<rdfs:label>individual organism specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002649 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002649">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003498"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000655"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002444"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000655"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>blood microbiology assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An organism detection assay that detects microorganisms in a blood specimen.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1064</obo:IAO_0000233>
<rdfs:label>blood microbiology assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002650 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002650">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000873"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>biopsy</obo:IAO_0000111>
<obo:IAO_0000112>Biopsy of a potentially cancerous mole.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen collection that obtains a sample of tissue or cell from a living multicellular organism body for diagnostic purposes by means intended to be minimally invasive.</obo:IAO_0000115>
<obo:IAO_0000117>Damion Dooley</obo:IAO_0000117>
<obo:IAO_0000117>Nicole Vasilevsky</obo:IAO_0000117>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Biopsy</obo:IAO_0000119>
<rdfs:label>biopsy</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002651 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002651">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002654"/>
<obo:IAO_0000111>image guided biopsy</obo:IAO_0000111>
<obo:IAO_0000112>Image-guided needle biopsy allows a doctor to biopsy suspicious areas that aren't readily seen or felt through skin, such as in a prostate gland.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A biopsy which uses an imaging procedure to guide a needle biopsy.</obo:IAO_0000115>
<obo:IAO_0000117>Damion Dooley</obo:IAO_0000117>
<obo:IAO_0000118>image guided needle biopsy</obo:IAO_0000118>
<obo:IAO_0000118>image-guided biopsy</obo:IAO_0000118>
<obo:IAO_0000118>imaging guided biopsy</obo:IAO_0000118>
<obo:IAO_0000119>https://www.mayoclinic.org/diseases-conditions/cancer/in-depth/biopsy/art-20043922</obo:IAO_0000119>
<rdfs:label>image guided biopsy</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002652 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002652">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002651"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000982"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>computed tomography assisted biopsy</obo:IAO_0000111>
<obo:IAO_0000112>A CT Guided Biopsy is a procedure performed by a radiologist to obtain a small tissue sample through a needle.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A needle biopsy guided by real-time computed tomography (CT) scan images.</obo:IAO_0000115>
<obo:IAO_0000117>Damion Dooley</obo:IAO_0000117>
<obo:IAO_0000118>CT Assisted Biopsy</obo:IAO_0000118>
<obo:IAO_0000118>CT Guided Biopsy</obo:IAO_0000118>
<obo:IAO_0000118>Computed Tomography Assisted Biopsy</obo:IAO_0000118>
<obo:IAO_0000118>Computed Tomography-Guided Needle Biopsy</obo:IAO_0000118>
<obo:IAO_0000119>http://purl.obolibrary.org/obo/NCIT_C137909</obo:IAO_0000119>
<rdfs:label>computed tomography assisted biopsy</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002653 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002653">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002651"/>
<obo:IAO_0000111>ultrasound-guided needle biopsy</obo:IAO_0000111>
<obo:IAO_0000112>An ultrasound-guided needle biopsy uses sound waves to help locate a nodule or abnormality within the thyroid.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A needle biopsy guided by ultrasound visualization.</obo:IAO_0000115>
<obo:IAO_0000117>Damion Dooley</obo:IAO_0000117>
<obo:IAO_0000119>https://www.oncolink.org/cancer-treatment/procedures-diagnostic-tests/biopsy-procedures/ultrasound-guided-needle-biopsy</obo:IAO_0000119>
<rdfs:label>ultrasound-guided needle biopsy</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002654 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002654">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002650"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000436"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>needle biopsy</obo:IAO_0000111>
<obo:IAO_0000112>A needle biopsy is often used on suspicious breast lumps and enlarged lymph nodes that a doctor can feel through a patient's skin.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A biopsy that uses a hollow needle to extract cells.</obo:IAO_0000115>
<obo:IAO_0000117>Damion Dooley</obo:IAO_0000117>
<obo:IAO_0000119>https://www.mayoclinic.org/tests-procedures/needle-biopsy/about/pac-20394749</obo:IAO_0000119>
<rdfs:label>needle biopsy</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002655 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002655">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002654"/>
<obo:IAO_0000111>fine needle aspiration biopsy</obo:IAO_0000111>
<obo:IAO_0000112>A fine needle aspiration biopsy is commonly performed in order to test for cancer.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A biopsy that uses a thin needle to extract cells.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000118>FNA</obo:IAO_0000118>
<obo:IAO_0000118>FNAB</obo:IAO_0000118>
<obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769667/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>fine needle aspiration biopsy</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002656 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002656">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002654"/>
<obo:IAO_0000111>core needle biopsy</obo:IAO_0000111>
<obo:IAO_0000112>A core needle biopsy can remove more tissue than a fine needle biopsy, and therefore can provide more information about the cells and tissue removed.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A biopsy that uses a hollow tube to collect a core of tissue.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis, Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000118>CNB</obo:IAO_0000118>
<obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769667/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>core needle biopsy</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002657 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002657">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002650"/>
<obo:IAO_0000111>surgical biopsy</obo:IAO_0000111>
<obo:IAO_0000112>Surgical biopsy may be required to collect hard-to-reach tissue.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A biopsy involving a surgical incision into an organism to access the biopsy material.</obo:IAO_0000115>
<obo:IAO_0000117>Damion Dooley</obo:IAO_0000117>
<obo:IAO_0000118>excisional biopsy</obo:IAO_0000118>
<obo:IAO_0000118>open biopsy</obo:IAO_0000118>
<obo:IAO_0000119>https://www.mayoclinic.org/diseases-conditions/cancer/in-depth/biopsy/art-20043922</obo:IAO_0000119>
<rdfs:label>surgical biopsy</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002660 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002660">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002650"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0010414"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>abdominal wall fat pad biopsy</obo:IAO_0000111>
<obo:IAO_0000112>The makeup of fat in the abdominal wall can be investigated by fat biopsy.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A biopsy involving the collection of a small part of the abdominal wall fat pad.</obo:IAO_0000115>
<obo:IAO_0000117>Nicole Vasilevsky, Damion Dooley</obo:IAO_0000117>
<obo:IAO_0000118>abdominal wall biopsy</obo:IAO_0000118>
<obo:IAO_0000118>fat biopsy</obo:IAO_0000118>
<obo:IAO_0000119>https://www.ucsfbenioffchildrens.org/tests/003841.html</obo:IAO_0000119>
<rdfs:label>abdominal wall fat pad biopsy</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002661 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002661">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002650"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002415"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>tail biopsy</obo:IAO_0000111>
<obo:IAO_0000112>A mouse tail biopsy was performed to collect material for DNA extraction.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A biopsy involving the collection of the tip of a mamallian tail.</obo:IAO_0000115>
<obo:IAO_0000117>Nicole Vasilevsky, Damion Dooley</obo:IAO_0000117>
<obo:IAO_0000118>snip</obo:IAO_0000118>
<obo:IAO_0000119>http://web.jhu.edu/animalcare/policies/Tail%20Biopsy%20of%20Mice.pdf</obo:IAO_0000119>
<rdfs:label>tail biopsy</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002662 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002662">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002650"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002371"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>bone marrow biopsy</obo:IAO_0000111>
<obo:IAO_0000112>A bone marrow biopsy removes bone with the marrow inside to look at under a microscope</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A biopsy where a small amount of bone and a small amount of fluid and bone marrow are collected.</obo:IAO_0000115>
<obo:IAO_0000117>Nicole Vasilevsky</obo:IAO_0000117>
<obo:IAO_0000119>http://www.webmd.com/cancer/bone-marrow-aspiration-and-biopsy</obo:IAO_0000119>
<rdfs:label>bone marrow biopsy</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002663 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002663">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002650"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002199"/>
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<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
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<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>cytotoxicity after adoptive transfer|in vivo assay</obo:OBI_9991118>
<rdfs:label>in vivo assay measuring epitope specific T cell killing resulting from the adoptive transfer of epitope specific T cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002672 -->
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<obo:IAO_0000111>ELISA measuring epitope specific perforin release by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An enzyme-linked immunosorbent assay that detects epitope specific perforin release by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>perforin release|ELISA</obo:OBI_9991118>
<rdfs:label>ELISA measuring epitope specific perforin release by T cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002673 -->
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<obo:IAO_0000111>enrichment culture medium</obo:IAO_0000111>
<obo:IAO_0000112>Selenite broth is an enrichment culture medium used to selectively isolate Salmonella species.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A culture medium that is designed to favor the growth of a particular microorganism or cells over others, enriching a sample for the microorganism or cells of interest.</obo:IAO_0000115>
<obo:IAO_0000117 rdf:resource="https://orcid.org/0000-0002-6601-2165"/>
<obo:IAO_0000117 rdf:resource="https://orcid.org/0000-0002-8844-9165"/>
<obo:IAO_0000118>isolation medium</obo:IAO_0000118>
<obo:IAO_0000119 rdf:resource="https://en.wikipedia.org/wiki/Enrichment_culture"/>
<dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2020-03-08T22:04:07Z</dc:date>
<rdfs:label>enrichment culture medium</rdfs:label>
<rdfs:seeAlso rdf:resource="https://github.com/obi-ontology/obi/issues/997"/>
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<!-- http://purl.obolibrary.org/obo/OBI_0002674 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
<obo:IAO_0000111>case series study design</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 22213493</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A study design that samples only subjects who have experienced a particular event (outcome or exposure). Such a design, in contrast to a cohort study, does not permit calculation of absolute risk as non-case subjects are not included.</obo:IAO_0000115>
<obo:IAO_0000117>http://orcid.org/0000-0002-8844-9165</obo:IAO_0000117>
<obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/22213493</obo:IAO_0000119>
<rdfs:label>case series design</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002675 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002675">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002082"/>
<obo:IAO_0000111>massively parallel reporter assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An assay in which multiplexing the construction and interrogation of larger libraries of reporter constructs allows measurement of the transcriptional regulatory activities of thousands to hundreds of thousands of DNA sequences.</obo:IAO_0000115>
<obo:IAO_0000117>Damion Dooley</obo:IAO_0000117>
<obo:IAO_0000118>MPRA</obo:IAO_0000118>
<obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364389/</obo:IAO_0000119>
<rdfs:label>massively parallel reporter assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002676 -->
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<obo:IAO_0000111>in vivo assay measuring a T cell epitope specific response after adoptive transfer of epitope specific T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An efficacy of T cell epitope intervention experiment that is performed after adoptive transfer of epitope specfic T cells.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>in vivo response after adoptive transfer|in vivo assay</obo:OBI_9991118>
<rdfs:label>in vivo assay measuring a T cell epitope specific response after adoptive transfer of epitope specific T cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002677 -->
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<obo:IAO_0000111>in vivo assay measuring a B cell epitope specific response after adoptive transfer of epitope specific antibodies or B cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An efficacy of B cell epitope intervention experiment that is performed after adoptive transfer of epitope specific antibodies or B cells.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>in vivo response after adoptive transfer|in vivo assay</obo:OBI_9991118>
<rdfs:label>in vivo assay measuring a B cell epitope specific response after adoptive transfer of epitope specific antibodies or B cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002678 -->
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<obo:IAO_0000111>in vivo assay measuring T cell epitope specific disease exacerbation resulting from the adoptive transfer of epitope specific T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An efficacy of T cell epitope intervention experiment that uses a disease exacerbation in vivo intervention experiment after adoptive transfer of epitope specfic T cells.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>disease exacerbation after adoptive transfer|in vivo assay</obo:OBI_9991118>
<rdfs:label>in vivo assay measuring T cell epitope specific disease exacerbation resulting from the adoptive transfer of epitope specific T cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002679 -->
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<obo:IAO_0000111>vacuum-assisted biopsy needle</obo:IAO_0000111>
<obo:IAO_0000112>Vacuum-assisted biopsy needles come in two varieties: a non-tethered design and a needle design requiring tethering cable to a vacuum source.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000115 xml:lang="en">A core biopsy needle integrated with a vacuum system which facilitates the collection of specimen material.</obo:IAO_0000115>
<obo:IAO_0000117>Damion Dooley</obo:IAO_0000117>
<obo:IAO_0000119>https://www.researchgate.net/publication/330227873</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1163</obo:IAO_0000233>
<rdfs:label>vacuum-assisted biopsy needle</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002680 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002680">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001187"/>
<obo:IAO_0000111>pseudovirus entry assay</obo:IAO_0000111>
<obo:IAO_0000112>“Inhibition of MERS-CoV-spike-mediated pseudovirus entry by the HKU4 S1 domain “ (from https://doi.org/10.1073/pnas.1405889111); “protease treatment did not enhance pseudotype entry in the absence of host receptor “; “bat-derived cell lines derived from other species were infected with VSV-reporter particles pseudotyped with chimeric spikes and luciferase was measured as readout for cell entry” (from https://doi.org/10.1038/s41564-020-0688-y) ; “teicoplanin could inhibit the entry of HIV-1-2019-nCoV-S pseudoviruses with the IC50 value of 1.66 uM” (from https://doi.org/10.1101/2020.02.05.935387)</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures the entry in target cells of reporter viral particles that express an envelope protein of a different virus of interest.</obo:IAO_0000115>
<obo:IAO_0000117>Thomas Lemberger</obo:IAO_0000117>
<obo:IAO_0000118>pseudotype cell entry</obo:IAO_0000118>
<obo:IAO_0000118>pseudotype entry</obo:IAO_0000118>
<obo:IAO_0000118>pseudotyped particle cell entry assay</obo:IAO_0000118>
<obo:IAO_0000118>pseudovirus cell entry</obo:IAO_0000118>
<obo:IAO_0000119>Figure 1c in https://doi.org/10.1038/s41564-020-0688-y or Materials & Method in https://www.pnas.org/content/111/34/12516</obo:IAO_0000119>
<rdfs:label>pseudovirus entry assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002681 -->
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<obo:IAO_0000111>glass bottle</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A container with a narrow neck that is made of glass.</obo:IAO_0000115>
<obo:IAO_0000117>VEuPathDB</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1117</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>glass bottle</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002682 -->
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<obo:IAO_0000111>glass bottle coated with insecticides</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A glass bottle that coated with material designed to control insects.</obo:IAO_0000115>
<obo:IAO_0000117>VEuPathDB</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1117</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>glass bottle coated with insecticides</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002683 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002683">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000415"/>
<obo:IAO_0000111>short interspersed nuclear elements polymerase chain reaction</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A polymerase chain reaction that amplifies short interspersed nuclear elements (SINEs).</obo:IAO_0000115>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000118>short interspersed elements PCR</obo:IAO_0000118>
<obo:IAO_0000119>PMID: 12711348</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1117</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>short interspersed nuclear elements polymerase chain reaction</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002684 -->
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<obo:IAO_0000111>nested polymerase chain reaction</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A polymerase chain reaction with modification intended to reduce non-specific binding in products due to the amplification of unexpected primer binding sites. The nested polymerase chain reaction (PCR) involves the use of two primer sets and two successive PCR reactions. The first set of primers are designed to anneal to sequences upstream from the second set of primers and are used in an initial PCR reaction.</obo:IAO_0000115>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000118>nested PCR</obo:IAO_0000118>
<obo:IAO_0000118>nested-PCR</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Nested_polymerase_chain_reaction</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1117</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>nested polymerase chain reaction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002685 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002685">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600053"/>
<obo:IAO_0000111>immunoelectrophoresis</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An electrophoresis that separates and characterize proteins based on reaction with antibodies.</obo:IAO_0000115>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000118>IEP</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Immunoelectrophoresis</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1117</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>immunoelectrophoresis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002686 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002686">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600053"/>
<obo:IAO_0000111>counter current immunoelectrophoresis</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An electrophoresis in which antigen and antibody move in opposite directions and form precipitates in the area between the cells where they meet in concentrations of optimal proportions.</obo:IAO_0000115>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>http://www.ispybio.com/search/protocols/ie%20protocol2.pdf</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1117</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>counter current immunoelectrophoresis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002687 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002687">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001494"/>
<obo:IAO_0000111>ligase detection reaction</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A linear amplification that uses a thermostable ligase to amplify a piece of DNA. Because the enzyme retains activity after multiple thermal cycles, the ligations may be repeated to linearly increase product.</obo:IAO_0000115>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000118>LDR</obo:IAO_0000118>
<obo:IAO_0000119>MIRO:20000103</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1117</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>ligase detection reaction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002688 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002688">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600058"/>
<obo:IAO_0000111>loop-mediated isothermal amplification</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An enzymatic amplification in which a piece of DNA is amplified at a constant temperature of 60 - 65 degree C using either two or three sets of primers and a polymerase with high strand displacement activity in addition to a replication activity. This amplification does not need thermal cyclers and may be a low cost alternative to PCR.</obo:IAO_0000115>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000118>LAMP</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Loop-mediated_isothermal_amplification</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1117</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>loop-mediated isothermal amplification</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002689 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002689">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000268"/>
<obo:IAO_0000111>detection of pathogenic organisms objective</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An organism feature identification objective that aims to detect whether an organism contains pathogenic organisms.</obo:IAO_0000115>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1117</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>detection of pathogenic organisms objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002690 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002690">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000268"/>
<obo:IAO_0000111>insecticide resistance detection objective</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An organism feature identification objective that aims to detect insecticide resistance of an insect.</obo:IAO_0000115>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1117</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>insecticide resistance detection objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002691 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002691">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000655"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>arthropod meal of blood specimen</obo:IAO_0000111>
<obo:IAO_0000112>A specimen used in a blood meal assay to determine what is the source of blood ingested by a mosquito.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen of the blood ingested by an arthropod.</obo:IAO_0000115>
<obo:IAO_0000116>The mosquito feeds on a human for example, ingests the blood of the human, this blood is then taken from the tummy of a mosquito and a PCR may be run on this specimen to identify that the mosquito definitely fed on a human.</obo:IAO_0000116>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000118>blood meal</obo:IAO_0000118>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1117</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>arthropod meal of blood specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002692 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002692">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000415"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>polymerase chain reaction assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that uses polymerase chain reaction technique to amplify DNA.</obo:IAO_0000115>
<obo:IAO_0000117>VEuPathDB</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1117</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>polymerase chain reaction assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002693 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002693">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001121"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001121"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001051"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001051"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000086"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000732"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000732"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600055"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>restriction fragment length polymorphism assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that uses digestion of DNA with specific restriction enzymes followed by gel electropheresis to detect differences in the sizes of the generated fragments that are due to genetic differences (polymorphisms) in homologous sequences.</obo:IAO_0000115>
<obo:IAO_0000117>VEuPathDB</obo:IAO_0000117>
<obo:IAO_0000118>RFLP</obo:IAO_0000118>
<obo:IAO_0000118>restriction fragment length polymorphism</obo:IAO_0000118>
<obo:IAO_0000118>restriction fragment length polymorphism analysis</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Restriction_fragment_length_polymorphism</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1117</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>restriction fragment length polymorphism assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002694 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002694">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001051"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001051"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>DNA fingerprinting assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay to identify a specific individual organism from a DNA specimen by looking at unique patterns in their DNA.</obo:IAO_0000115>
<obo:IAO_0000117>VEuPathDB</obo:IAO_0000117>
<obo:IAO_0000118>DNA finger printing</obo:IAO_0000118>
<obo:IAO_0000118>DNA fingerprint</obo:IAO_0000118>
<obo:IAO_0000118>DNA fingerprinting</obo:IAO_0000118>
<obo:IAO_0000118>DNA profiling</obo:IAO_0000118>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1117</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>DNA fingerprinting assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002695 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002695">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002690"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>insecticide resistance assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that aims to detect the presence and/or frequency of resistance to insecticides in an organism or organism population.</obo:IAO_0000115>
<obo:IAO_0000117>VEuPathDB</obo:IAO_0000117>
<obo:IAO_0000118>resistance identification/monitoring</obo:IAO_0000118>
<obo:IAO_0000119>MIRO:20000001</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1117</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>insecticide resistance assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002696 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002696">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002695"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002690"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>insecticide resistance by monitoring known mutations assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An insecticide resistance assay that detects, in a population, presence and frequency of mutant alleles for previously characterized mutations with insecticide resistance phenotypes.</obo:IAO_0000115>
<obo:IAO_0000117>VEuPathDB</obo:IAO_0000117>
<obo:IAO_0000118>monitoring known mutations</obo:IAO_0000118>
<obo:IAO_0000119>MIRO:20000096</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1117</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>insecticide resistance by monitoring known mutations assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002697 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002697">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002695"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0003824"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002690"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>insecticide resistance by detecting enzyme activity assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An insecticide resistance assay that is based on determination the catalytic activity of an enzyme associated with insecticide resistance phenotypes.</obo:IAO_0000115>
<obo:IAO_0000117>VEuPathDB</obo:IAO_0000117>
<obo:IAO_0000118>metabolic resistance assay</obo:IAO_0000118>
<obo:IAO_0000119>MIRO:20000003</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1117</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>insecticide resistance by detecting enzyme activity assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002698 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002698">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002695"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002690"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>insecticide resistance bioassay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An insecticide resistance assay that is typically conducted to measure the effects of a substance on a living organism.</obo:IAO_0000115>
<obo:IAO_0000117>VEuPathDB</obo:IAO_0000117>
<obo:IAO_0000118>bioassay</obo:IAO_0000118>
<obo:IAO_0000119>MIRO:20000058</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1117</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>insecticide resistance bioassay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002699 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002699">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002697"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
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<obo:IAO_0000117>VEuPathDB</obo:IAO_0000117>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1117</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1117</obo:IAO_0000233>
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<obo:IAO_0000118>blood meal analysis</obo:IAO_0000118>
<obo:IAO_0000119>IRO:0000135</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1117</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>blood meal assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002733 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002733">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002732"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002686"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002691"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>blood meal by counter current immunoelectrophoresis assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A blood meal assay that uses a counter current immunoelectrophoresis technique.</obo:IAO_0000115>
<obo:IAO_0000117>VEuPathDB</obo:IAO_0000117>
<obo:IAO_0000118>CIE</obo:IAO_0000118>
<obo:IAO_0000118>countercurrent immunoelectrophoresis</obo:IAO_0000118>
<obo:IAO_0000119>IRO:0000136</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1117</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>blood meal by counter current immunoelectrophoresis assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002734 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002734">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002694"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002732"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001051"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001051"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002691"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>DNA based blood meal finger printing assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A DNA fingerprinting assay that uses DNA extracted from blood meal fed organism, such as insect.</obo:IAO_0000115>
<obo:IAO_0000117>VEuPathDB</obo:IAO_0000117>
<obo:IAO_0000118>DNA based blood meal finger printing</obo:IAO_0000118>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000119>VSMO:0001307</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1117</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>DNA based blood meal finger printing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002735 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002735">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003498"/>
<obo:IAO_0000111>organism detection by size assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An organism detection assay that is based on the size of organism.</obo:IAO_0000115>
<obo:IAO_0000117>VEuPathDB</obo:IAO_0000117>
<obo:IAO_0000118>by size</obo:IAO_0000118>
<obo:IAO_0000119>IRO:0000145</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1117</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>organism detection by size assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002736 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002736">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003498"/>
<obo:IAO_0000111>organism detection by cross mating assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An organism detection assay that is based on genetic crossings between specimens collected in the field to determine whether fertile progeny is produced.</obo:IAO_0000115>
<obo:IAO_0000117>VEuPathDB</obo:IAO_0000117>
<obo:IAO_0000118>cross mating experiment</obo:IAO_0000118>
<obo:IAO_0000119>MIRO:30000036</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1117</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>organism detection by cross mating assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002737 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002737">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003498"/>
<obo:IAO_0000111>organism detection by cytological chromosome examination assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An organism detection assay that is based on analysis of polytene chromosomes through cytological examination of the banding pattern of the species.</obo:IAO_0000115>
<obo:IAO_0000117>VEuPathDB</obo:IAO_0000117>
<obo:IAO_0000118>cytological chromosome examination</obo:IAO_0000118>
<obo:IAO_0000119>MIRO:30000037</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1117</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>organism detection by cytological chromosome examination assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002738 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002738">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003498"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600053"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>organism detection by isoenzyme electrophoresis assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An organism detection assay that is based on electrophoresis to determine the isozymes that are present in a specific population to determine the species.</obo:IAO_0000115>
<obo:IAO_0000117>VEuPathDB</obo:IAO_0000117>
<obo:IAO_0000118>isoenzyme electrophoresis</obo:IAO_0000118>
<obo:IAO_0000119>MIRO:30000038</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1117</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>organism detection by isoenzyme electrophoresis assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002739 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002739">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003498"/>
<obo:IAO_0000111>organism detection by morphological examination assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An organism detection assay that is based on examination of morphology and the use of specific taxonomic keys to determine the species of the specimen.</obo:IAO_0000115>
<obo:IAO_0000117>VEuPathDB</obo:IAO_0000117>
<obo:IAO_0000118>morphological examination</obo:IAO_0000118>
<obo:IAO_0000119>MIRO:30000039</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1117</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>organism detection by morphological examination assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002740 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002740">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002692"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003498"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000415"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>organism detection by PCR assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An organism detection assay that is based on PCR.</obo:IAO_0000115>
<obo:IAO_0000117>VEuPathDB</obo:IAO_0000117>
<obo:IAO_0000118>PCR-based species identification</obo:IAO_0000118>
<obo:IAO_0000119>MIRO:30000040</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1117</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>organism detection by PCR assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002741 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002741">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003498"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0302903"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>organism detection by specific DNA hybridization assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An organism detection assay that is based on DNA hybrdization.</obo:IAO_0000115>
<obo:IAO_0000117>VEuPathDB</obo:IAO_0000117>
<obo:IAO_0000118>species specific DNA hybridization</obo:IAO_0000118>
<obo:IAO_0000119>MIRO:30000041</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1117</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>organism detection by specific DNA hybridization assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002742 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002742">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003498"/>
<obo:IAO_0000111>organism detection by salinity tolerance assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An organism detection assay of mosquito species that is on the basis of mosquito survival depending on the salt concentration in the water used to lay their eggs to differentiate between morphologically very similar species.</obo:IAO_0000115>
<obo:IAO_0000117>VEuPathDB</obo:IAO_0000117>
<obo:IAO_0000118>salinity tolerance tests</obo:IAO_0000118>
<obo:IAO_0000119>MIRO:30000042</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1117</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>organism detection by salinity tolerance assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002743 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002743">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000086"/>
<obo:IAO_0000111 xml:lang="en">molecular label role</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A reagent role inhering in a molecular entity intended to associate with some molecular target to serve as a proxy for the presence, abundance, or location of this target in a detection of molecular label assay.</obo:IAO_0000115>
<obo:IAO_0000116>MHB (9-29-13): 'molecular label role' imported from the Reagent Ontology and replaced OBI:OBI_0000140 (label role).
JZ (3-30-20): discussed on the OBI call. Since the REO was never actually registered, we decided to adopt the term into OBI and replaced REO_0000171 by newly assigned ID: OBI:0002743.</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Group: OBI</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">molecular tracer role</obo:IAO_0000118>
<obo:IAO_0000119>OBI developer call, 3-12-12</obo:IAO_0000119>
<obo:IAO_0000233 xml:lang="en">https://github.com/obi-ontology/obi/issues/1135</obo:IAO_0000233>
<rdfs:label xml:lang="en">molecular label role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002744 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002744">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002743"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001879"/>
<obo:IAO_0000111 xml:lang="en">molecular label</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A molecular reagent intended to associate with some molecular target to serve as a proxy for the presence, abundance, or location of this target in a detection of molecular label assay</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">JZ (3-30-20): discussed on the OBI call. Since the REO was never actually registered, we decided to adopt the term into OBI and replaced OBI:0002744 by newly assigned ID: OBI:0002744.</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Group: OBI</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">molecular tracer</obo:IAO_0000118>
<obo:IAO_0000119>OBI developer call, 3-12-12</obo:IAO_0000119>
<obo:IAO_0000233 xml:lang="en">https://github.com/obi-ontology/obi/issues/1135</obo:IAO_0000233>
<rdfs:label xml:lang="en">molecular label</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002745 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002745">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002654"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002679"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>vacuum-assisted biopsy</obo:IAO_0000111>
<obo:IAO_0000112>A vacuum assisted biopsy can remove an area of abnormal cells from breast tissue.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A biopsy performed with a needle augmented with a vacuum device.</obo:IAO_0000115>
<obo:IAO_0000117>Damion Dooley</obo:IAO_0000117>
<obo:IAO_0000118>VAB</obo:IAO_0000118>
<obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769667/</obo:IAO_0000119>
<rdfs:label>vacuum-assisted biopsy</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002746 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002746">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002508"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0007311"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>induced sputum specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A sputum specimen that is collected from an organism following its inhalation of a nebulized salt solution.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>PMC3297553</obo:IAO_0000119>
<rdfs:label>induced sputum specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002747 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002747">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<obo:IAO_0000111 xml:lang="en">passage process</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A material processing that consists of first growing an organism in an environmental system and then removing the organism to be grown in another environmental system, a process which may be repeated with the objective of altering the organism or increasing its number.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Serial_passage</obo:IAO_0000119>
<obo:IAO_0000119>https://www.merriam-webster.com/dictionary/passage</obo:IAO_0000119>
<rdfs:label xml:lang="en">passage process</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002748 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002748">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002747"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">passage history record</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A data item that is about the sequence of environmental systems in each of which is grown an organism in a passage process.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">John Judkins</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">https://en.wikipedia.org/wiki/Serial_passage</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">https://www.merriam-webster.com/dictionary/passage</obo:IAO_0000119>
<rdfs:label xml:lang="en">passage history record</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002750 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002750">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400103"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
<owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/OBI_0002755"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>Oxford Nanopore MinION</obo:IAO_0000111>
<obo:IAO_0000112>Approaches to Whole Mitochondrial Genome Sequencing on the Oxford Nanopore MinION</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A portable DNA sequencer which is manufactured by the Oxford Nanopore Technologies corporation, that uses consumable flow cells producing up to 30 Gb of DNA sequence data per flow cell. The sequencer produces real-time results and utilizes nanopore technology with up to 512 nanopore channels in the sensor array.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Bonita Lam</obo:IAO_0000117>
<obo:IAO_0000118>ONT MinION, MinION</obo:IAO_0000118>
<obo:IAO_0000119>https://nanoporetech.com/products/minion</obo:IAO_0000119>
<rdfs:label>Oxford Nanopore MinION</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002751 -->
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<obo:IAO_0000111>Oxford Nanopore GridION Mk1</obo:IAO_0000111>
<obo:IAO_0000112>Nineteen libraries were constructed and sequenced on nineteen different R9.4 FlowCells using the GridION X5 sequencer</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A DNA sequencer that is manufactured by the Oxford Nanopore Technologies corporation, that can run and analyze up to five individual flow cells producing up to 150 Gb of data per run. The sequencer produces real-time results and utilizes nanopore technology with the option of running the flow cells concurrently or individually.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Bonita Lam</obo:IAO_0000117>
<obo:IAO_0000118>Oxford Nanopore GridION X5, GridION Mk1</obo:IAO_0000118>
<obo:IAO_0000119>https://nanoporetech.com/products/gridion</obo:IAO_0000119>
<rdfs:label>Oxford Nanopore GridION Mk1</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002752 -->
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<obo:IAO_0000111>Oxford Nanopore PromethION</obo:IAO_0000111>
<obo:IAO_0000112>Structural variants identified by Oxford Nanopore PromethION sequencing of the human genome.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A DNA sequencer that is manufactured by the Oxford Nanopore Technologies corporation, capable of running up to 48 flow cells and producing up to 7.6 Tb of data per run. The sequencer produces real-time results and utilizes Nanopore technology, with each flow cell allowing up to 3,000 nanopores to be sequencing simultaneously.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Bonita Lam</obo:IAO_0000117>
<obo:IAO_0000118>PromethION</obo:IAO_0000118>
<obo:IAO_0000119>https://nanoporetech.com/products/promethion</obo:IAO_0000119>
<rdfs:label>Oxford Nanopore PromethION</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002753 -->
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<obo:IAO_0000111>PRO-cap</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Precision nuclear run-on and sequencing to detect Pol II initiation sites</obo:IAO_0000115>
<obo:IAO_0000117>Bonita Lam</obo:IAO_0000117>
<obo:IAO_0000118>PRO-CAP</obo:IAO_0000118>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1102</obo:IAO_0000233>
<rdfs:label>PRO-cap</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002754 -->
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<obo:IAO_0000111 xml:lang="en"></obo:IAO_0000111>
<obo:IAO_0000111 xml:lang="en">cDNA library</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">cDNA library lacks the non-coding and regulatory elements found in genomic DNA</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A collection of DNA molecules with sequences complementary to a specified set of mRNA molecules and commonly developed by enzymatic reverse transcription.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Dan Berrios</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">modified from Wikipedia</obo:IAO_0000119>
<rdfs:label xml:lang="en">cDNA library</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002756 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002756">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001930"/>
<obo:IAO_0000111 xml:lang="en">ordinal value specification</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A categorical value specification in which the available categories were created with an explicit order.</obo:IAO_0000115>
<obo:IAO_0000116>https://en.wikipedia.org/wiki/Ordinal_data provides references for follow-up, but more than one OBI developer has objected to "...whose levels have natural, ordered categories and the distances between those categories is not known..."
Separate from that, an OBI mechanism for asserting the order of ordinal values specification levels with OWL has not been determined yet.</obo:IAO_0000116>
<obo:IAO_0000117>Mark Andrew Miller, ORCID:0000-0001-9076-6066</obo:IAO_0000117>
<obo:IAO_0000119>Bjoern Peters in https://github.com/obi-ontology/obi/issues/862</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/862</obo:IAO_0000233>
<rdfs:label xml:lang="en">ordinal value specification</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002759 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002759">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001271"/>
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<obo:IAO_0000111>ribosomal RNA-depleted RNA sequencing assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An RNA-seq assay in which highly abundant ribosomal RNAs are removed from total RNA before sequencing, resulting in more efficient transcript/gene detection.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>rRNA-deleted RNA sequencing assay</obo:IAO_0000118>
<obo:IAO_0000119>PMID:29556074</obo:IAO_0000119>
<obo:IAO_0000234>CFDE</obo:IAO_0000234>
<rdfs:label>ribosomal RNA-depleted RNA sequencing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002760 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002760">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001271"/>
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<obo:IAO_0000111>metatranscriptome sequencing assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An RNA-seq assay that determines the RNA sequence of microbial transcripts from a microbioal community of mixed species from a given microbiome.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000119>PMID:31450270</obo:IAO_0000119>
<obo:IAO_0000234>CFDE</obo:IAO_0000234>
<rdfs:label>metatranscriptome sequencing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002761 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002761">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<obo:IAO_0000111>lipid profiling assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay assay that detects and identifies lipids resulting from biochemical and cellular metabolism.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>lipidomic assay</obo:IAO_0000118>
<obo:IAO_0000119>OBI metabolite profiling assay</obo:IAO_0000119>
<obo:IAO_0000234>CFDE</obo:IAO_0000234>
<rdfs:label>lipid profiling assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002762 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002762">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002039"/>
<obo:IAO_0000111>single-nucleus ATAC-seq</obo:IAO_0000111>
<obo:IAO_0000112>snATAC-seq can be used to dissect heterogeneity and delineate gene regulatory sequences in complex tissues, and uncover both the cell types and the regulatory elements in each cell type without prior knowledge.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An ATAC-seq assay in which single nuclei are isolated from frozen tissue samples, through a protocol designed to maximally preserve nucleus integrity during sample processing and optimize transposase-mediated fragmentation of chromatin in individual nuclei.</obo:IAO_0000115>
<obo:IAO_0000117>Mark Andrew Miller, ORCID:0000-0001-9076-6066</obo:IAO_0000117>
<obo:IAO_0000118>snATAC-seq</obo:IAO_0000118>
<obo:IAO_0000119>http://www.biorxiv.org/content/early/2017/07/06/159137</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/864</obo:IAO_0000233>
<obo:IAO_0000234>ENCODE</obo:IAO_0000234>
<rdfs:label>single-nucleus ATAC-seq</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002763 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002763">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001960"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002767"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000181"/>
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<obo:IAO_0000111>16s ribosomal gene sequencing assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An amplicon sequencing assay in which the amplicon is derived from universal primers used to amplify the 16S ribosomal RNA gene from isolate bacterial genomic DNA or metagenomic DNA from a microbioal community. Resulting sequences are compared to reference 16S sequence databases to identify or classify bacteria present within a given sample.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>16S rRNA sequencing assay</obo:IAO_0000118>
<obo:IAO_0000119>PMID:31450270</obo:IAO_0000119>
<obo:IAO_0000234>CFDE</obo:IAO_0000234>
<rdfs:label>16s ribosomal gene sequencing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002764 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002764">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002039"/>
<obo:IAO_0000111>single-cell ATAC-seq</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An ATAC assay designed to robustly map the accessible genome of individual cells, using sequencing integrated into a programmable microfluidics platform, in order to provide insights into cell-to-cell variation in accessibility profiles.</obo:IAO_0000115>
<obo:IAO_0000117>Mark Andrew Miller, ORCID:0000-0001-9076-6066</obo:IAO_0000117>
<obo:IAO_0000118>scATAC-seq</obo:IAO_0000118>
<obo:IAO_0000119>http://www.nature.com/nature/journal/v523/n7561/full/nature14590.html</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/864</obo:IAO_0000233>
<obo:IAO_0000234>ENCODE</obo:IAO_0000234>
<rdfs:label>single-cell ATAC-seq</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002765 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002765">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000615"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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<obo:IAO_0000111>microbiome protein expression profiling assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A protein expression profiling assay of microbial proteins extracted from a microbioal community of mixed species from a given microbiome.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>metaproteomic assay</obo:IAO_0000118>
<obo:IAO_0000119>PMID:31450270</obo:IAO_0000119>
<obo:IAO_0000234>CFDE</obo:IAO_0000234>
<rdfs:label>microbiome protein expression profiling assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002766 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002766">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<obo:IAO_0000111>cytokine assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay to study presence, concentration, or amount of cytokines.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000119>PMID:23603216</obo:IAO_0000119>
<obo:IAO_0000234>CFDE</obo:IAO_0000234>
<rdfs:label>cytokine assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002767 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002767">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600047"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001108"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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<obo:IAO_0000111>amplicon sequencing assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A sequencing assay in which a DNA or RNA input molecule is amplified by PCR and the product sequenced.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000119>PMID:29628929</obo:IAO_0000119>
<obo:IAO_0000119>PMID:31450270</obo:IAO_0000119>
<obo:IAO_0000234>CFDE</obo:IAO_0000234>
<rdfs:label>amplicon sequencing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002768 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002768">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002623"/>
<obo:IAO_0000111>whole virome sequencing assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A whole metagenome sequencing assay that intends to provide information on multiple genome sequences from different viruses present in the same input sample.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000119>OBI:0002623</obo:IAO_0000119>
<obo:IAO_0000234>CFDE</obo:IAO_0000234>
<rdfs:label>whole virome sequencing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002769 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002769">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001404"/>
<obo:IAO_0000111 xml:lang="en">karyotype information</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A genetic characteristics information that is about the number and appearance of chromosomes in the nucleus of an eukaryotic cell.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">EFO_0004426 karyotype</obo:IAO_0000119>
<obo:IAO_0000233 xml:lang="en">https://github.com/obi-ontology/obi/issues/1097</obo:IAO_0000233>
<obo:IAO_0000234 xml:lang="en">VEuPathDB</obo:IAO_0000234>
<rdfs:label xml:lang="en">karyotype information</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002770 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002770">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002769"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002771"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">partial karyotype information</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A karyotype information that is about the structural variation of partial genome rather than whole genome.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233 xml:lang="en">https://github.com/obi-ontology/obi/issues/1097</obo:IAO_0000233>
<obo:IAO_0000234 xml:lang="en">VEuPathDB</obo:IAO_0000234>
<rdfs:label xml:lang="en">partial karyotype information</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002771 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002771">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002769"/>
<obo:IAO_0000111 xml:lang="en">full karyotype information</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A karyotype information that is about the structural variation of the whole genome.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI group</obo:IAO_0000119>
<obo:IAO_0000233 xml:lang="en">https://github.com/obi-ontology/obi/issues/1097</obo:IAO_0000233>
<rdfs:label xml:lang="en">full karyotype information</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002772 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002772">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002756"/>
<obo:IAO_0000111 xml:lang="en">presence or over-threshold value specification</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An ordinal value specification that indicates that either
a) an analyte or mesaurand is present in an evaluant, or
b) that the amount of analyte/measurand detected is over some predetermined threshold.</obo:IAO_0000115>
<obo:IAO_0000117>Mark Andrew Miller, ORCID:0000-0001-9076-6066</obo:IAO_0000117>
<obo:IAO_0000119>LOINC User's Guide, Version 2.68, PUBLISHED JUNE 2020, page 32</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1202</obo:IAO_0000233>
<rdfs:comment>bump</rdfs:comment>
<rdfs:label xml:lang="en">presence or over-threshold value specification</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002773 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002773">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>single-value binding of antibody with reporter to antigen assay</obo:IAO_0000111>
<obo:IAO_0000112>Detection of SARS-CoV-2 IgG antibodies by an immunoassay method, such as enzyme-linked immunosorbent assay. This test is used in conjunction with SARS-CoV-2 IgA and IgM to aid in the diagnosis of COVID-19 and in the identification of individuals infected with SARS-CoV-2.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that detects the linking of antigens and antibodies via special signaling mechanisms, such as EIA, ELISA, chemiluminescence, etc. that produces one measure (quantitative or qualitative) of the analyte of interest</obo:IAO_0000115>
<obo:IAO_0000116>LOINC indicates that this class would not include flow cytometry or any technique that can determine the localization of an analyte, such as peroxidase immune staining or indirect immunofluorescence (IFA)</obo:IAO_0000116>
<obo:IAO_0000117>Mark Andrew Miller, ORCID:0000-0001-9076-6066</obo:IAO_0000117>
<obo:IAO_0000118>IA</obo:IAO_0000118>
<obo:IAO_0000118>immunoassay</obo:IAO_0000118>
<obo:IAO_0000119>LOINC User's Guide, Version 2.68, PUBLISHED JUNE 2020, page 47</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1203</obo:IAO_0000233>
<rdfs:label>single-value binding of antibody with reporter to antigen assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002774 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002774">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0100016"/>
<obo:IAO_0000111>platelet-poor plasma specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A blood plasma specimen that is the output of some platelet-poor plasma preparation and is the portion of plasma that contains fewer than 10,000 platelets per microliter.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Matthew Diller</obo:IAO_0000117>
<rdfs:label>platelet-poor plasma specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002775 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002775">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600014"/>
<obo:IAO_0000111 xml:lang="en">platelet-poor plasma preparation process</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A material component separation process in which (1) whole blood is first centrifuged to separate red blood cells from blood plasma, which forms the supernatant, and (2) the blood plasma is then centrifuged to separate platelets from the plasm.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON: Matthew Diller</obo:IAO_0000117>
<rdfs:label xml:lang="en">platelet-poor plasma preparation process</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002776 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002776">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200077"/>
<obo:IAO_0000111>cytometry analysis by automated gating</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A gating in which the output of a flow- or mass- cytometry experiment is separated into gates that were set by an algorithm in order to quantify the frequency of different cell populations of interest.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>CMI-PB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1226</obo:IAO_0000233>
<rdfs:label>cytometry analysis by automated gating</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002777 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002777">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200077"/>
<obo:IAO_0000111>cytometry analysis by manual gating</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A gating in which the output of a flow- or mass- cytometry experiment is separated into gates that were set by a human operator in order to quantify the frequency of different cell populations of interest.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>CMI-PB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1226</obo:IAO_0000233>
<rdfs:label>cytometry analysis by manual gating</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002778 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002778">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002783"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002785"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000659"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0003126"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002781"/>
<obo:IAO_0000111>tracheal aspirate specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is collected with a suctioning tube from the trachea.</obo:IAO_0000115>
<obo:IAO_0000117>Asiyah Yu Lin ORCID:0000-0003-2620-0345</obo:IAO_0000117>
<obo:IAO_0000118>tracheal wash specimen</obo:IAO_0000118>
<obo:IAO_0000119>PMID:25338241</obo:IAO_0000119>
<rdfs:label>tracheal aspirate specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002779 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002779">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000917"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002600"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000659"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0005921"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000917"/>
<obo:IAO_0000111>mid-turbinate nasal swab specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is collected with a mid-turbinate nasal swab from the turbinate area of the nasal cavity.</obo:IAO_0000115>
<obo:IAO_0000117>Asiyah Yu Lin ORCID:0000-0003-2620-0345</obo:IAO_0000117>
<obo:IAO_0000119>https://seattlechildrenslab.testcatalog.org/catalogs/185/files/11633</obo:IAO_0000119>
<rdfs:label>mid-turbinate nasal swab specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002780 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002780">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_2000006"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002785"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000659"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001826"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2000006"/>
<obo:IAO_0000111>nasal aspirate specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is collected with a suctioning tube from the nasal cavity.</obo:IAO_0000115>
<obo:IAO_0000117>Asiyah Yu Lin ORCID:0000-0003-2620-0345</obo:IAO_0000117>
<obo:IAO_0000118>nasal wash specimen</obo:IAO_0000118>
<obo:IAO_0000118>nasopharyngeal aspirate</obo:IAO_0000118>
<obo:IAO_0000119>Asiyah Yu Lin ORCID:0000-0003-2620-0345</obo:IAO_0000119>
<rdfs:label>nasal aspirate specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002781 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002781">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002783"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002785"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000659"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001558"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002783"/>
<obo:IAO_0000111>lower respiratory tract aspirate specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is collected with a suctioning tube from the lower respiratory tract.</obo:IAO_0000115>
<obo:IAO_0000117>Asiyah Yu Lin ORCID:0000-0003-2620-0345</obo:IAO_0000117>
<obo:IAO_0000118>lower respiratory tract wash specimen</obo:IAO_0000118>
<obo:IAO_0000119>Asiyah Yu Lin ORCID:0000-0003-2620-0345</obo:IAO_0000119>
<rdfs:label>lower respiratory tract aspirate specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002782 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002782">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_upper respiratory specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from the upper respiratory tract</obo:IAO_0000115>
<obo:IAO_0000117>Asiyah Yu Lin ORCID:0000-0003-2620-0345</obo:IAO_0000117>
<obo:IAO_0000119>Asiyah Yu Lin ORCID:0000-0003-2620-0345</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
<obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/OBI_2000006"/>
<rdfs:label>obsolete_upper respiratory specimen</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002783 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002783">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_2000005"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000659"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001558"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2000005"/>
<obo:IAO_0000111>lower respiratory tract specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from the lower respiratory tract.</obo:IAO_0000115>
<obo:IAO_0000117>Asiyah Yu Lin ORCID:0000-0003-2620-0345</obo:IAO_0000117>
<obo:IAO_0000119>Asiyah Yu Lin ORCID:0000-0003-2620-0345</obo:IAO_0000119>
<rdfs:label>lower respiratory tract specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002784 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002784">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000917"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002600"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000659"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_3000016"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000917"/>
<obo:IAO_0000111>anterior nasal swab specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from the anterior nasal wall</obo:IAO_0000115>
<obo:IAO_0000117>Asiyah Yu Lin ORCID:0000-0003-2620-0345</obo:IAO_0000117>
<obo:IAO_0000119>Asiyah Yu Lin ORCID:0000-0003-2620-0345</obo:IAO_0000119>
<rdfs:label>anterior nasal swab specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002785 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002785">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
<obo:IAO_0000111 xml:lang="en">aspiration specimen collection</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Procedure using suction, usually with a thin needle and syringe, to remove bodily fluid or tissue.</obo:IAO_0000115>
<obo:IAO_0000117>Asiyah Yu Lin|ORCID:0000-0003-2620-0345</obo:IAO_0000117>
<obo:IAO_0000118>aspiration procedure</obo:IAO_0000118>
<obo:IAO_0000119 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=ncit&code=C15631</obo:IAO_0000119>
<rdfs:label xml:lang="en">aspiration specimen collection</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002786 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002786">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<obo:IAO_0000111>personal protective device</obo:IAO_0000111>
<obo:IAO_0000112>Examples of PPE include respirators, gloves, aprons, fall protection, and full body suits, as well as head, eye and foot protection.</obo:IAO_0000112>
<obo:IAO_0000112>PPE is equipment worn by a worker to minimize exposure to specific hazards.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A device which is a wearable garment designed to protect the wearer's body from injury or infection.</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-8844-9165</obo:IAO_0000117>
<obo:IAO_0000118>PPE</obo:IAO_0000118>
<obo:IAO_0000118>personal protective equipment</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Personal_protective_equipment</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1193</obo:IAO_0000233>
<rdfs:label>personal protective device</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002787 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002787">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002786"/>
<obo:IAO_0000111>face mask</obo:IAO_0000111>
<obo:IAO_0000112>A systematic review on the efficacy of face coverings against respiratory viruses analyzed 19 randomized trials and concluded that use of face masks and respirators appeared to be protective in both health care and community settings</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A personal protective device worn over the nose and mouth as a respiratory filter to inhibit the flow of particles.</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-8844-9165</obo:IAO_0000117>
<obo:IAO_0000118>face covering</obo:IAO_0000118>
<obo:IAO_0000118>respirator</obo:IAO_0000118>
<obo:IAO_0000119>Adapted from https://dictionary.cambridge.org/dictionary/english/face-mask</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1193</obo:IAO_0000233>
<rdfs:label>face mask</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002788 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002788">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002787"/>
<obo:IAO_0000111>non-medical mask</obo:IAO_0000111>
<obo:IAO_0000112>A non-medical mask may contain fabrics that are not regulated for use in surgical masks or respirators, or may not be designed to form a seal around the nose and mouth.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A face mask not manufactured according to medical equipment standards.</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-8844-9165</obo:IAO_0000117>
<obo:IAO_0000118>cloth mask</obo:IAO_0000118>
<obo:IAO_0000119>https://www.canada.ca/en/public-health/services/diseases/2019-novel-coronavirus-infection/prevention-risks/about-non-medical-masks-face-coverings.html</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1193</obo:IAO_0000233>
<rdfs:label>non-medical mask</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002789 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002789">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002787"/>
<obo:IAO_0000111>medical mask</obo:IAO_0000111>
<obo:IAO_0000112>The finding of a much higher rate of infection in the cloth mask arm could be interpreted as harm caused by cloth masks, efficacy of medical masks, or most likely a combination of both.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A face mask manufactured according to a recognized medical equipment standard.</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-9578-0788</obo:IAO_0000117>
<obo:IAO_0000118>surgical mask</obo:IAO_0000118>
<obo:IAO_0000119>https://www.canada.ca/en/public-health/services/diseases/2019-novel-coronavirus-infection/prevention-risks/about-non-medical-masks-face-coverings.html</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1193</obo:IAO_0000233>
<rdfs:label>medical mask</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002790 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002790">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002787"/>
<obo:IAO_0000111>N95 respirator</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A face mask that meets the U.S. National Institute for Occupational Safety and Health (NIOSH) N95 classification of air filtration, meaning that it filters at least 95% of incoming airborne particles.</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-8844-9165</obo:IAO_0000117>
<obo:IAO_0000118>N95</obo:IAO_0000118>
<obo:IAO_0000118>N95 face mask</obo:IAO_0000118>
<obo:IAO_0000118>N95 facemask</obo:IAO_0000118>
<obo:IAO_0000118>N95 respirator mask</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/N95_mask</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1193</obo:IAO_0000233>
<rdfs:label>N95 respirator</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002791 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002791">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002786"/>
<obo:IAO_0000111>face shield</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A personal protective device used to protect the wearer's entire face (or part of it) from hazards such as flying objects and road debris, chemical splashes, or alternately potentially infectious materials.</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-8844-9165</obo:IAO_0000117>
<obo:IAO_0000118>faceshield</obo:IAO_0000118>
<obo:IAO_0000118>splash shield</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Face_shield</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1193</obo:IAO_0000233>
<rdfs:label>face shield</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002792 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002792">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002800"/>
<obo:IAO_0000111>patient gown</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A personal protective clothing item which is a gown designed for use by a patient to facilitate caregiving by medical staff.</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-8844-9165</obo:IAO_0000117>
<obo:IAO_0000118>hospital gown</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Patient_gown</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1193</obo:IAO_0000233>
<rdfs:label>patient gown</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002793 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002793">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002800"/>
<obo:IAO_0000111>scrubs</obo:IAO_0000111>
<obo:IAO_0000112>Examples consist of a short-sleeve V-necked shirt and drawstring pants or a short-sleeve calf-length dress, a tie-back or bouffant-style cap, a mask, a surgical gown, latex gloves, and supportive closed-toe shoes.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A personal protective clothing item which is sterilized and which is worn by a health care professional. It can reference a shirt and pants or dress, and depending on medical protocol, may include a medical cap.</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-8844-9165</obo:IAO_0000117>
<obo:IAO_0000118>scrub clothing item</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Scrubs_(clothing)</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1193</obo:IAO_0000233>
<rdfs:label>scrubs</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002794 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002794">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002792"/>
<obo:IAO_0000111>reusable patient gown</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A patient gown intended to be reused after being laundered.</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-8844-9165</obo:IAO_0000117>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Patient_gown</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1193</obo:IAO_0000233>
<rdfs:label>reusable patient gown</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002795 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002795">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002792"/>
<obo:IAO_0000111>disposable patient gown</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A patient gown intended for a single period of continuous use and then disposed of.</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-8844-9165</obo:IAO_0000117>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Patient_gown</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1193</obo:IAO_0000233>
<rdfs:label>disposable patient gown</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002796 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002796">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002800"/>
<obo:IAO_0000111>medical gown</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A personal protective clothing item which is a gown worn by a medical professional in order to provide a barrier between patient and professional.</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-8844-9165</obo:IAO_0000117>
<obo:IAO_0000118>hospital gown</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Medical_gown</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1193</obo:IAO_0000233>
<rdfs:label>medical gown</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002797 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002797">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<obo:IAO_0000111>apron</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A garment which is worn over other clothing and covers mainly the front of the body.</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-8844-9165</obo:IAO_0000117>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Apron</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1193</obo:IAO_0000233>
<rdfs:label>apron</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002798 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002798">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002796"/>
<obo:IAO_0000111>surgical gown</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A medical gown which is subjected to a sterilization process and which is intended to be worn by a medical professional during surgical procedures.</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-8844-9165</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1193</obo:IAO_0000233>
<rdfs:label>surgical gown</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002799 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002799">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002800"/>
<obo:IAO_0000111>personal protective glove</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A personal protective device which is a glove.</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-8844-9165</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1193</obo:IAO_0000233>
<rdfs:label>personal protective glove</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002800 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002800">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002786"/>
<obo:IAO_0000111>personal protective clothing item</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A personal protective device which consists of a garment that serves in place of or in addition to regular body clothing.</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-8844-9165</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1193</obo:IAO_0000233>
<rdfs:label>personal protective clothing item</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002802 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002802">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002800"/>
<obo:IAO_0000111>laboratory coat</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A personal protective clothing item which is an overcoat worn by medical or laboratory professionals.</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-8844-9165</obo:IAO_0000117>
<obo:IAO_0000118>white coat</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/White_coat</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1193</obo:IAO_0000233>
<rdfs:label>laboratory coat</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002803 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002803">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002799"/>
<obo:IAO_0000111>medical glove</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A personal protective glove which is disposable and is used during medical examinations and procedures to help prevent cross-contamination between caregivers and patients.</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-8844-9165</obo:IAO_0000117>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Medical_glove</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1193</obo:IAO_0000233>
<rdfs:label>medical glove</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002804 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002804">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002799"/>
<obo:IAO_0000111>nitrile glove</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A personal protective glove which is made out of nitrile rubber.</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-8844-9165</obo:IAO_0000117>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Medical_glove</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1193</obo:IAO_0000233>
<rdfs:label>nitrile glove</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002805 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002805">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<obo:IAO_0000111>transparent partition</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A device which is a transparent constructed barrier, usually made out of acrylic (Plexiglass) or polycarbonate plastic, installed in facilities to intercept respiratory droplets, encourage physical distancing requirements.</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-8844-9165</obo:IAO_0000117>
<obo:IAO_0000118>transparent partition</obo:IAO_0000118>
<obo:IAO_0000119>https://ncceh.ca/content/blog/physical-barriers-covid-19-infection-prevention-and-control-commercial-settings</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1193</obo:IAO_0000233>
<rdfs:label>transparent droplet barrier</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002806 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002806">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002800"/>
<obo:IAO_0000111>footwear cover</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A personal protective device which is an impermiable material which covers a shoe or boot in order to prevent spread of specific environmental contaminants.</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-8844-9165</obo:IAO_0000117>
<obo:IAO_0000118>boot cover</obo:IAO_0000118>
<obo:IAO_0000118>shoe cover</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wiktionary.org/wiki/shoecover</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1193</obo:IAO_0000233>
<rdfs:label>footwear cover</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002807 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002807">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002806"/>
<obo:IAO_0000111>disposable footwear cover</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A footwear cover which is designed for a single period of continuous use and then disposed of.</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-8844-9165</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1193</obo:IAO_0000233>
<rdfs:label>disposable footwear cover</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002808 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002808">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002806"/>
<obo:IAO_0000111>reusable footwear cover</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A footwear cover which is designed for repeated use.</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-8844-9165</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1193</obo:IAO_0000233>
<rdfs:label>reusable footwear cover</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002809 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002809">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002790"/>
<obo:IAO_0000111>surgical N95 respirator</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A N95 respirator which has been approved by the FDA as a surgical mask.</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-8844-9165</obo:IAO_0000117>
<obo:IAO_0000118>healthcare respirator</obo:IAO_0000118>
<obo:IAO_0000118>medical respirator</obo:IAO_0000118>
<obo:IAO_0000118>surgical N95</obo:IAO_0000118>
<obo:IAO_0000118>surgical N95 respirator</obo:IAO_0000118>
<obo:IAO_0000119>https://multimedia.3m.com/mws/media/1794572O/surgical-n95-vs-standard-n95-which-to-consider.pdf</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1193</obo:IAO_0000233>
<rdfs:label>surgical N95 respirator</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002810 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002810">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002800"/>
<obo:IAO_0000111>protective coverall</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A personal protective clothing item which is a loose fitting coverall for ease of movement, with sleeves, full leggings and often a hood to cover the head. These can also include overshoe pieces to cover footwear and protect against contamination.</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-8844-9165</obo:IAO_0000117>
<obo:IAO_0000119>https://www.safeopedia.com/definition/863/disposable-coveralls</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1193</obo:IAO_0000233>
<rdfs:label>protective coverall</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002811 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002811">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002800"/>
<obo:IAO_0000111>protective sleeve</obo:IAO_0000111>
<obo:IAO_0000112>A protective sleeve can be designed to provide protection from heat, welding spatter or hot metal, chemicals, sharp objects, paint or other liquids.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A personal protective clothing item which is a protective cover worn over the arm.</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-8844-9165</obo:IAO_0000117>
<obo:IAO_0000119>https://www.safeopedia.com/definition/974/protective-sleeves</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1193</obo:IAO_0000233>
<rdfs:label>protective sleeve</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002812 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002812">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002800"/>
<obo:IAO_0000111>protective apron</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A personal protective clothing item which is an apron.</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-8844-9165</obo:IAO_0000117>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Apron</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1193</obo:IAO_0000233>
<rdfs:label>protective apron</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002813 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002813">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002800"/>
<obo:IAO_0000111>medical cap</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A personal protective device which is worn on the head that helps prevent transmission of contaminants contained in hair and scalp.</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-8844-9165</obo:IAO_0000117>
<obo:IAO_0000118>bouffant cap</obo:IAO_0000118>
<obo:IAO_0000118>bouffant hat</obo:IAO_0000118>
<obo:IAO_0000118>medical bonnet</obo:IAO_0000118>
<obo:IAO_0000118>scrub cap</obo:IAO_0000118>
<obo:IAO_0000118>surgical hat</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Scrubs_(clothing)</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1193</obo:IAO_0000233>
<rdfs:label>medical cap</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002814 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002814">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<obo:IAO_0000111>specimen collection device</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A device used to collect a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-8844-9165</obo:IAO_0000117>
<rdfs:label>specimen collection device</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002816 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002816">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000601"/>
<obo:IAO_0000111>chromatography vial</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A vial with cap and container material suited to optical, sanitary and handling requirements of chromatography.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:<http://msi-ontology.sourceforge.net></obo:IAO_0000119>
<obo:IAO_0000119>http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01117</obo:IAO_0000119>
<rdfs:label>chromatography vial</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002819 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002819">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002814"/>
<obo:IAO_0000111>specimen pad</obo:IAO_0000111>
<obo:IAO_0000112>An absorbent pad and its accompanying container are designed to provide safe storage and transport to various degrees for diagnostic and clinical samples, infectious and hazardous materials, chemicals, pharmaceuticals and environmental samples.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A sample collection device consisting of a soft flexible, absorbent pad usually made from natural material such as gauze or cotton, used to absorb specimen fluid or particulate matter.</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-8844-9165</obo:IAO_0000117>
<obo:IAO_0000118>absorbant pad</obo:IAO_0000118>
<obo:IAO_0000118>polysponge</obo:IAO_0000118>
<obo:IAO_0000118>sample pad</obo:IAO_0000118>
<obo:IAO_0000118>sampling sponge</obo:IAO_0000118>
<obo:IAO_0000118>specimen sponge</obo:IAO_0000118>
<obo:IAO_0000118>surface wipe</obo:IAO_0000118>
<obo:IAO_0000118>swab</obo:IAO_0000118>
<obo:IAO_0000119>Derived from NCIT sponge definition.</obo:IAO_0000119>
<rdfs:label>specimen pad</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002820 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002820">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002814"/>
<obo:IAO_0000111>specimen collection swab stick</obo:IAO_0000111>
<obo:IAO_0000112>A swab stick allows a worker to collect samples without touching the inside of the bag</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen collection device which is a specimen pad attached to a long handle used to collect specimen material.</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-8844-9165</obo:IAO_0000117>
<obo:IAO_0000118>polyprobe</obo:IAO_0000118>
<obo:IAO_0000118>sponge probe</obo:IAO_0000118>
<obo:IAO_0000118>sponge stick</obo:IAO_0000118>
<obo:IAO_0000118>sponge-stick</obo:IAO_0000118>
<obo:IAO_0000119>https://medical-dictionary.thefreedictionary.com/swab</obo:IAO_0000119>
<rdfs:label>specimen collection swab stick</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002821 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002821">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<obo:IAO_0000111>cotton swab</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A device which is a cotton pad mounted on one or both ends of a stick.</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-8844-9165</obo:IAO_0000117>
<obo:IAO_0000118>Q-tip</obo:IAO_0000118>
<obo:IAO_0000118>swab-sampler</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Cotton_swab</obo:IAO_0000119>
<rdfs:label>cotton swab</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002822 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002822">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002814"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002819"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>drag swab</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen collection device consisting of a specimen pad made of sterile gauze which is aseptically attached to a pole by clips or to a string</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-8844-9165</obo:IAO_0000117>
<obo:IAO_0000119>https://www.fda.gov/food/laboratory-methods-food/environmental-sampling-and-detection-salmonella-poultry-houses</obo:IAO_0000119>
<rdfs:label>drag swab</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002823 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002823">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002820"/>
<obo:IAO_0000111>pre-moistened swab stick</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A specimen collection swab stick that is pre-moistened with liquid prior to sampling.</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-8844-9165</obo:IAO_0000117>
<rdfs:label>pre-moistened swab stick</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002824 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002824">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002814"/>
<obo:IAO_0000111>surface wipe</obo:IAO_0000111>
<obo:IAO_0000112>Surface sampling procedures involved the use of polyester wipes, swabs, contact slides (two types), and adhesive tapes; a gelatin filter was used to sample the air.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A sample collection device consisting of a thin, less absorbent sheet, used to collect material from surfaces.</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-8844-9165</obo:IAO_0000117>
<obo:IAO_0000119>https://www.science.gov/topicpages/s/surface+wipe+sampling.html</obo:IAO_0000119>
<rdfs:label>surface wipe</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002830 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002830">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<obo:IAO_0000111>catheter</obo:IAO_0000111>
<obo:IAO_0000112>A catheter left inside the body, either temporarily or permanently, may be referred to as an indwelling catheter.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A device which is a flexible tube inserted into a body and which enables transfer of fluids into or out of a body.</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-8844-9165</obo:IAO_0000117>
<obo:IAO_0000119>http://purl.bioontology.org/ontology/MESH/D057785</obo:IAO_0000119>
<rdfs:label>catheter</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002897 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002897">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000066"/>
<obo:IAO_0000111>surveillance process</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An investigation in which some entity is monitored, and data concerning that entity collected, interpreted, and disseminated, for the purpose of managing, directing, or protecting that entity, or some other entity.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Shane Babcock, OBI</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1181</obo:IAO_0000233>
<obo:IAO_0000234>IDO, VEuPathDB</obo:IAO_0000234>
<rdfs:label>surveillance process</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002898 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002898">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000174"/>
<obo:IAO_0000111>cluster study group role</obo:IAO_0000111>
<obo:IAO_0000112>A cluster study group consisting of eight pregnant women who lived close enough to each other so that a community promoter could readily walk to each compound.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study group role that is the result of the allocation of a cluster of study-defined groupings of people in a clinical trial to receive a specific intervention/treatment, or no intervention, according to the trial's protocol.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Brianna Lindsay</obo:IAO_0000117>
<obo:IAO_0000118>cluster study arm</obo:IAO_0000118>
<obo:IAO_0000119>ClinEpiDB</obo:IAO_0000119>
<rdfs:label>cluster study group role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002899 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002899">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000174"/>
<obo:IAO_0000111>compound study group role</obo:IAO_0000111>
<obo:IAO_0000112>A compound study group consisting of geographically proximate households that share a common water source.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study group role that is the result of the allocation of a compound of geographically-proximate households with a shared component in a clinical trial to receive a specific intervention/treatment, or no intervention, according to the trial's protocol.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Brianna Lindsay</obo:IAO_0000117>
<obo:IAO_0000118>compound study arm</obo:IAO_0000118>
<obo:IAO_0000119>ClinEpiDB</obo:IAO_0000119>
<rdfs:label>compound study group role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002900 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002900">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400065"/>
<obo:IAO_0000111>ultraviolet light source</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A light source that provides ultraviolet (UV) light for use in a distant area using a delivery system.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000118>UV light source</obo:IAO_0000118>
<obo:IAO_0000119>Person: Jie Zheng</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1200</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>ultraviolet light source</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002901 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002901">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400065"/>
<obo:IAO_0000111>visible light source</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A light source that provides visible light for use in a distant area using a delivery system.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>Person: Jie Zheng</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1200</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>visible light source</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002902 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002902">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400065"/>
<obo:IAO_0000111>solar light source</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A light source that light is produced from solar energy.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Person: Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>Person: Chris Stoeckert</obo:IAO_0000119>
<obo:IAO_0000119>Person: Jie Zheng</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1200</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>solar light source</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002904 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002904">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002919"/>
<obo:IAO_0000111>adult arthropod specimen collection process</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A live arthropod specimen collection process in which the arthropods are in the adult stage.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>collection of adults</obo:IAO_0000118>
<obo:IAO_0000119>MIRO:30000052</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>adult arthropod specimen collection process</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002905 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002905">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002912"/>
<obo:IAO_0000111>animal-biting arthropod specimen collection by aspiration</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An arthropod specimen collection by aspiration that occurs while the arthropod is biting an animal.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>animal biting catch</obo:IAO_0000118>
<obo:IAO_0000119>MIRO:30000012</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>animal-biting arthropod specimen collection by aspiration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002906 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002906">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002905"/>
<obo:IAO_0000111>animal-biting outdoor arthropod specimen collection by aspiration</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An animal-biting arthropod specimen collection by aspiration that occurs outside a building.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>animal biting catch - outdoors</obo:IAO_0000118>
<obo:IAO_0000119>MIRO:30000014</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>animal-biting outdoor arthropod specimen collection by aspiration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002907 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002907">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002913"/>
<obo:IAO_0000111>aquatic arthropod specimen collection process</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An arthropod specimen collection process that has the objective of collecting mosquitoes from an aquatic environment.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>aquatic environment catch</obo:IAO_0000118>
<obo:IAO_0000119>MIRO:30000048</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>aquatic arthropod specimen collection process</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002908 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002908">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002912"/>
<obo:IAO_0000111>arthropod resting in animal house specimen collection by aspiration</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An arthropod specimen collection by aspiration that catches specimens resting inside an animal house.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>animal shed resting catch</obo:IAO_0000118>
<obo:IAO_0000119>MIRO:30000027</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>arthropod resting in animal house specimen collection by aspiration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002909 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002909">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002911"/>
<obo:IAO_0000111>arthropod resting outdoors on artificial support specimen collection by aspiration</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An arthropod resting outdoors specimen collection by aspiration that occurs while the arthropod rests on a processed material such as a wall or furniture.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>outdoors shelter catch - artificial</obo:IAO_0000118>
<obo:IAO_0000119>MIRO:30000026</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>arthropod resting outdoors on artificial support specimen collection by aspiration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002910 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002910">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002911"/>
<obo:IAO_0000111>arthropod resting outdoors on natural support specimen collection by aspiration</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An arthropod resting outdoors specimen collection by aspiration that occurs while the arthropod rests on an unprocessed material such as a plant.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>outdoors shelter catch - natural</obo:IAO_0000118>
<obo:IAO_0000119>MIRO:30000025</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>arthropod resting outdoors on natural support specimen collection by aspiration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002911 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002911">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002905"/>
<obo:IAO_0000111>arthropod resting outdoors specimen collection by aspiration</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An animal-biting arthropod specimen collection by aspiration that occurs while the arthropod is resting outside a building during a period of inactivity.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>outdoors shelter catch</obo:IAO_0000118>
<obo:IAO_0000119>MIRO:30000024</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>arthropod resting outdoors specimen collection by aspiration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002912 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002912">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002904"/>
<obo:IAO_0000111>arthropod specimen collection by aspiration</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A live arthropod specimen collection process that involves the use of an aspirator, a device which draws an arthropod by suction into a container.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>catch by aspiration</obo:IAO_0000118>
<obo:IAO_0000119>MIRO:30000043</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>arthropod specimen collection by aspiration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002913 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002913">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
<obo:IAO_0000111>arthropod specimen collection process</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen collection process that has the objective of collecting arthropods as specimens.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>collection of arthropods</obo:IAO_0000118>
<obo:IAO_0000118>field population catch</obo:IAO_0000118>
<obo:IAO_0000119>MIRO:30000044</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>arthropod specimen collection process</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002914 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002914">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002912"/>
<obo:IAO_0000111>human-biting arthropod specimen collection by aspiration</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An arthropod specimen collection by aspiration that occurs while the arthropod is biting a human.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>man biting catch</obo:IAO_0000118>
<obo:IAO_0000119>MIRO:30000017</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>human-biting arthropod specimen collection by aspiration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002915 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002915">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002914"/>
<obo:IAO_0000111>human-biting indoor arthropod specimen collection by aspiration</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An arthropod specimen collection by aspiration that occurs while the arthropod is biting a human inside a building.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>man biting catch - indoors</obo:IAO_0000118>
<obo:IAO_0000119>MIRO:30000019</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>human-biting indoor arthropod specimen collection by aspiration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002916 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002916">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002914"/>
<obo:IAO_0000111>human-biting outdoor arthropod specimen collection by aspiration</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An arthropod specimen collection by aspiration designed to catch specimens that are in the process of biting a human outside a building.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>man biting catch - outdoors</obo:IAO_0000118>
<obo:IAO_0000119>MIRO:30000018</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>human-biting outdoor arthropod specimen collection by aspiration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002917 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002917">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002918"/>
<obo:IAO_0000111>knockdown arthropod specimen collection by pyrethrum spray</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A knockdown arthropod specimen collection process in which the pesticide is pyrethrum.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>pyrethrum spray catch</obo:IAO_0000118>
<obo:IAO_0000119>MIRO:30000023</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>knockdown arthropod specimen collection by pyrethrum spray</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002918 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002918">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002919"/>
<obo:IAO_0000111>knockdown arthropod specimen collection process</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An arthropod specimen collection process that involves exposing arthropods to pesticide, then collecting them once they become dead or immobilized.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>knockdown collection</obo:IAO_0000118>
<obo:IAO_0000119>IRO:0000014</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>knockdown arthropod specimen collection process</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002919 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002919">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002913"/>
<obo:IAO_0000111>live arthropod specimen collection process</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An arthropod specimen collection process meant to collect live specimens.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>catch of live specimens</obo:IAO_0000118>
<obo:IAO_0000119>MIRO:30000044</obo:IAO_0000119>
<obo:IAO_0000119>VSMO:0001445</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>live arthropod specimen collection process</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002920 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002920">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<obo:IAO_0000111>arthropod trap</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device designed to catch arthropods.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>MIRO:30000011</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>arthropod trap</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002921 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002921">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002939"/>
<obo:IAO_0000111>artificial pit shelter</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An arthropod trap, consisting of a pit dug in the ground to provide a space for arthropods to rest and be collected.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>IRO:0000005</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>artificial pit shelter</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002922 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002922">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002920"/>
<obo:IAO_0000111>baited net trap</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An arthropod trap designed to work with an animal (which could be human) inside a netted structure. This structure is designed so that an arthropod, attracted by the animal, can fly into the netted structure but can neither escape nor reach the animal.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>baited net trap</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002923 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002923">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002920"/>
<obo:IAO_0000111>barrier trap</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An arthropod trap consisting of a static physical barrier designed to funnel arthropods in flight into a container.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>IRO:0000017</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>barrier trap</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002924 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002924">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
<owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/OBI_0002903"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>BG-Counter</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device manufactured by BioGents that is designed to count mosquitoes passing through the device, differentiating the mosquitoes from other arthropods.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>IRO:0000143</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>BG-Counter</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002925 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002925">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002920"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
<owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/OBI_0002903"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>BG-Sentinel trap</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An arthropod trap that is manufactured by Biogents and is designed to attract arthropods through the use of a motorized fan to mimic convection currents produced by a human. The current also pulls arthropods into the trap, where a layer of gauze prevents the arthropods from escaping along with the air current.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>IRO:0000028</obo:IAO_0000119>
<obo:IAO_0000119>VSMO:0001906</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>BG-Sentinel trap</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002926 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002926">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002930"/>
<obo:IAO_0000111>Centers for Disease Control and Prevention light trap</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A light trap that is designed similarly to the New Jersey trap—in that it uses motorized suction and light attractant—and is powered by a six-volt battery.</obo:IAO_0000115>
<obo:IAO_0000116>This trap is also designed to be lightweight and operate in environments in which electricity may be scarce.</obo:IAO_0000116>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>CDC light trap</obo:IAO_0000118>
<obo:IAO_0000119>IRO:0000163</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>Centers for Disease Control and Prevention light trap</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002927 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002927">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<obo:IAO_0000111>dipper for arthropod immatures</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that is designed for the collection of arthropod larvae or pupae from water and has the shape of a ladle or a pan.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>dipper for immatures</obo:IAO_0000118>
<obo:IAO_0000119>VSMO:0001479</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>dipper for arthropod immatures</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002928 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002928">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002930"/>
<obo:IAO_0000111>encephalitis virus surveillance trap</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A light trap that uses carbon dioxide as attractant. The trap consists of a container of dry ice with holes in the bottom to allow the carbon dioxide to flow downward into a separate container, in which a motorized fan creates suction to collect arthropods.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>EVS trap</obo:IAO_0000118>
<obo:IAO_0000119>IRO:0000029</obo:IAO_0000119>
<obo:IAO_0000119>VSMO:0001295</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>encephalitis virus surveillance trap</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002929 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002929">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002920"/>
<obo:IAO_0000111>gravid trap</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An arthropod trap that is designed to collect gravid female arthropods or their eggs.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>IRO:0000030</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>gravid trap</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002930 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002930">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002920"/>
<obo:IAO_0000111>light trap</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An arthropod trap that uses light as an attractant.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>MIRO:30000065</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>light trap</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002931 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002931">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002930"/>
<obo:IAO_0000111>light trap for indoor use</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A light trap designed to be placed inside a building.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>indoor light trap</obo:IAO_0000118>
<obo:IAO_0000119>MIRO:30000009</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>light trap for indoor use</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002932 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002932">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002930"/>
<obo:IAO_0000111>light trap for outdoor use</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A light trap designed to be placed outside a building.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>outdoor light trap</obo:IAO_0000118>
<obo:IAO_0000119>MIRO:30000010</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>light trap for outdoor use</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002933 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002933">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002920"/>
<obo:IAO_0000111>Mosquito Magnet Pro trap</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An arthropod trap that is powered by propane and is designed to emit a combination of carbon dioxide, heat, water, and oct-1-en-3-ol attractants while simultaneously using suction to trap arthropods.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>IRO:0000022</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>Mosquito Magnet Pro trap</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002934 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002934">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002929"/>
<obo:IAO_0000111>MosquiTRAP</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A gravid trap consisting of an arthropod attractant and adhesive surface.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>IRO:0000140</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>MosquiTRAP</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002935 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002935">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002930"/>
<obo:IAO_0000111>New Jersey light trap</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A light trap that is designed to use motorized suction to trap arthropods in a collection bag once they approach the light attractant.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>New Jersey trap</obo:IAO_0000118>
<obo:IAO_0000119>IRO:0000031</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>New Jersey light trap</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002936 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002936">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002920"/>
<obo:IAO_0000111>Onderstepoort Veterinary Institute light-suction trap</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A light trap that is designed to use motorized suction to trap arthropods in a collection bag once they approach the attractant. The light is supplied by an 8 watt tube, and the fan providing the suction has an 11-centimeter diameter.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>OVI light-suction trap</obo:IAO_0000118>
<obo:IAO_0000119>IRO:0000154</obo:IAO_0000119>
<obo:IAO_0000119>Parasites Vectors 8, 239 (2015)</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>Onderstepoort Veterinary Institute light-suction trap</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002937 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002937">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002920"/>
<obo:IAO_0000111>outlet window trap</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An arthropod trap that is positioned adjacent to a window of a building and is designed to collect arthropods flying out of the building.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>outlet window trap</obo:IAO_0000118>
<obo:IAO_0000119>MIRO:30000020</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>outlet window trap</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002938 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002938">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002920"/>
<obo:IAO_0000111>ovitrap</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An arthropod trap that consists of a container holding a mesh layer above water and is designed to trap arthropods hatched from eggs dropped over the water by gravid females.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>oviposition trap</obo:IAO_0000118>
<obo:IAO_0000119>MIRO:30000016</obo:IAO_0000119>
<obo:IAO_0000119>VSMO:0001501</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>ovitrap</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002939 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002939">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002920"/>
<obo:IAO_0000111>resting arthropod trap</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An arthropod trap that is designed to be attractive to an arthropod as a place to rest during a period of inactivity.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>resting arthropod trap</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002940 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002940">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002939"/>
<obo:IAO_0000111>resting box trap</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An arthropod trap that consists of a box that is open on one end. The placement of the box and modifications to it are done in such a way that it becomes attractive to an arthropod as a place to rest during a period of inactivity.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>resting box catch</obo:IAO_0000118>
<obo:IAO_0000119>IRO:0000021</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>resting box trap</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002941 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002941">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002939"/>
<obo:IAO_0000111>resting bucket</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An arthropod trap that consists of a bucket, which is lined with fabric and placed on its side, and a wet cloth inside the bucket. The placement of the box and modifications to it are done in such a way that it becomes attractive to an arthropod as a place to rest during a period of inactivity (not actively seeking a host).</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>resting bucket catch</obo:IAO_0000118>
<obo:IAO_0000119>IRO:0000141</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>resting bucket</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002942 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002942">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002920"/>
<obo:IAO_0000111>Shannon trap</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An arthropod trap that is made of cloth and netting and is designed to be suspended from above (e.g. from a tree). It is also designed so that the arthropod enters the trap from beneath, being attracted to some bait, and is prevented from escaping upward by the suspended cloth, which allows them to be collected from the upper interior of the trap.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>shannon trap catch</obo:IAO_0000118>
<obo:IAO_0000119>IRO:0000191</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>Shannon trap</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002943 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002943">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002939"/>
<obo:IAO_0000111>sticky resting bucket</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An arthropod trap that consists of a bucket, which is lined with adhesive and placed on its side, and a wet cloth inside the bucket. The placement of the box and modifications to it are done in such a way that it becomes attractive to an arthropod as a place to rest during a period of inactivity. The trap is designed for arthropods to become caught in the adhesive so that they can be collected.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>sticky resting bucket catch</obo:IAO_0000118>
<obo:IAO_0000119>IRO:0000142</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>sticky resting bucket</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002944 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002944">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002939"/>
<obo:IAO_0000111>sticky trap</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An arthropod trap that is designed to capture arthropods resting on a surface by coating the surface with adhesive.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>sticky trap catch</obo:IAO_0000118>
<obo:IAO_0000119>IRO:0000128</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1217</obo:IAO_0000233>
<rdfs:label>sticky trap</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002945 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002945">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
<obo:IAO_0000111>population based design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design where the selection of the individuals that are included into the study are intended to be representative of all individuals in the a priori defined specific population and is done at the population level or among the population groups, generally to find the cause, incidence or spread of the disease or to see the response to the treatment, nutrition or environment.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>https://link.springer.com/referenceworkentry/10.1007%2F978-1-4419-1005-9_45, EFO_0001430 population based design</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1090</obo:IAO_0000233>
<rdfs:label>population based design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002946 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002946">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001977"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001501"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003368"/>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>fluorescence imaging-based apoptosis assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A type of cytometry assay in which fluorescent dyes are used to label and detect proteins or structures associated with molecular processes of apoptosis.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000119>url:http://lincsportal.ccs.miami.edu/beta/assays/1</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1243</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-LINCS</obo:IAO_0000234>
<rdfs:label>fluorescence imaging-based apoptosis assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002947 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002947">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000891"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001501"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003368"/>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>fluorescence imaging-based cell proliferation assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A type of cell proliferation assay in which fluorescent dyes are ued to label and detect proteins or structures that can be used to count cells.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>fluorescence imaging-based cell count assay</obo:IAO_0000118>
<obo:IAO_0000119>url:http://lincsportal.ccs.miami.edu/beta/assays/31</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1243</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-LINCS</obo:IAO_0000234>
<rdfs:label>fluorescence imaging-based cell proliferation assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002948 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002948">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001977"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001501"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003368"/>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>fluorescence imaging-based cell cycle state assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A type of cytometry assay in which fluorescent dyes are used to label and detect proteins or structures associated with particular cell cycle states.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000119>url:http://lincsportal.ccs.miami.edu/beta/assays/10</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1243</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-LINCS</obo:IAO_0000234>
<rdfs:label>fluorescence imaging-based cell cycle state assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002949 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002949">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001977"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001501"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003368"/>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>fluorescence imaging-based cell viability assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A type of cytometry assay in which fluorescent dyes are used to label and detect proteins or structures associated with cell viability.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000119>url:http://lincsportal.ccs.miami.edu/beta/assays/27</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1243</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-LINCS</obo:IAO_0000234>
<rdfs:label>fluorescence imaging-based cell viability assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002950 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002950">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001977"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001501"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003368"/>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>fluorescence imaging-based drug synergy assay</obo:IAO_0000111>
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<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000119>url:http://lincsportal.ccs.miami.edu/beta/assays/7</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1243</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-LINCS</obo:IAO_0000234>
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<!-- http://purl.obolibrary.org/obo/OBI_0002951 -->
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<obo:IAO_0000111>fluorescence imaging-based cell morphology assay</obo:IAO_0000111>
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<obo:IAO_0000119>CFDE</obo:IAO_0000119>
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<obo:IAO_0000119>Suvarna Nadendla</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1243</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-LINCS</obo:IAO_0000234>
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<!-- http://purl.obolibrary.org/obo/OBI_0002952 -->
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1243</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-LINCS</obo:IAO_0000234>
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<!-- http://purl.obolibrary.org/obo/OBI_0002953 -->
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<obo:IAO_0000115 xml:lang="en">A type of assay that measures the quantity and/or identity of proteins in their modficied and unmodified states where modifications include phosphorylation, methylation, acetylation, etc.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000119>CFDE</obo:IAO_0000119>
<obo:IAO_0000119>Michelle Giglio</obo:IAO_0000119>
<obo:IAO_0000119>Suvarna Nadendla</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1243</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-LINCS</obo:IAO_0000234>
<rdfs:label>protein state assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002954 -->
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<obo:IAO_0000111>fluorescence imaging-based protein phosphorylation state assay</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A type of protein state assay that employs high-throughput microscopy to measure levels of proteins in different phosphorylation states.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000119>url:http://lincsportal.ccs.miami.edu/beta/assays/15</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1243</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-LINCS</obo:IAO_0000234>
<rdfs:label>fluorescence imaging-based protein phosphorylation state assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002955 -->
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<obo:IAO_0000111>mass spectrometry-based protein state assay</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A type of protein state assay that employs mass spectrometry to measure levels of proteins in different phosphorylation states.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000119>CFDE</obo:IAO_0000119>
<obo:IAO_0000119>Michelle Giglio</obo:IAO_0000119>
<obo:IAO_0000119>Suvarna Nadendla</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1243</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-LINCS</obo:IAO_0000234>
<rdfs:label>mass spectrometry-based protein state assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002956 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002956">
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<obo:IAO_0000111>targeted, drug-modulated, mass spectrometry-based protein phoshporylation-state assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A type of mass spectrometry protein state assay that measures levels of a targeted set of proteins in different phosphorylation states in response to drug perturbations.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>P100 phosphoprotein quantification assay</obo:IAO_0000118>
<obo:IAO_0000119>PMID:26912667</obo:IAO_0000119>
<obo:IAO_0000119>PMID:29655704</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1243</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-LINCS</obo:IAO_0000234>
<rdfs:label>targeted, drug-modulated, mass spectrometry-based protein phoshporylation-state assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002957 -->
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<obo:IAO_0000111>reverse phase protein array profiling assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A type of protein state assay where tissue or cell samples are lysed and then spotted onto a slide which is probed with antibodies specific to proteins with and without post-translational modifications.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>RPLA assay</obo:IAO_0000118>
<obo:IAO_0000118>RPPA assay</obo:IAO_0000118>
<obo:IAO_0000118>reverse phase lysate array profiling assay</obo:IAO_0000118>
<obo:IAO_0000119>PMID: 17041095</obo:IAO_0000119>
<obo:IAO_0000119>PMID:31820393</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1243</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-LINCS</obo:IAO_0000234>
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<!-- http://purl.obolibrary.org/obo/OBI_0002958 -->
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<obo:IAO_0000111>SWATH-MS protein profiling assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A type of mass spectrometry assay using a data-independent acquisition method to identify target peptides.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>sequential window acquisition of all theoretical mass spectra protein profiling assay</obo:IAO_0000118>
<obo:IAO_0000119>PMID:30104418</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1243</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-LINCS</obo:IAO_0000234>
<rdfs:label>SWATH-MS protein profiling assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002959 -->
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<obo:IAO_0000111>tandem mass tag mass spectrometry assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A type of tandem mass spectrometry where isotopomer labels are employed for accurate quantification and identification of specific proteins.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000119>PMID:12713048</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1243</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-LINCS</obo:IAO_0000234>
<rdfs:label>tandem mass tag mass spectrometry assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002960 -->
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<obo:IAO_0000111>fluorescence imaging-based reporter gene assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A type of reporter gene assay that employs fluorescence imaging to detect a reporter gene's expression.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000119>CFDE</obo:IAO_0000119>
<obo:IAO_0000119>Michelle Giglio</obo:IAO_0000119>
<obo:IAO_0000119>Suvarna Nadendla</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1243</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-LINCS</obo:IAO_0000234>
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<!-- http://purl.obolibrary.org/obo/OBI_0002961 -->
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<obo:IAO_0000111>global chromatin profiling by mass spectrometry assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A type of epigenetic modification assay that employs targeted quantitative mass spectrometry to profile modifications of the core histones of chromatin.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>GCP</obo:IAO_0000118>
<obo:IAO_0000118>global chromatin epigenetic profiling</obo:IAO_0000118>
<obo:IAO_0000118>global chromatin profiling</obo:IAO_0000118>
<obo:IAO_0000119>PMID:25448295</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1243</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-LINCS</obo:IAO_0000234>
<rdfs:label>global chromatin profiling by mass spectrometry assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002962 -->
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<obo:IAO_0000111>kinase inhibitor assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A type of assay that identifies compounds that inhibit the activity of kinases.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000119>CFDE</obo:IAO_0000119>
<obo:IAO_0000119>Michelle Giglio</obo:IAO_0000119>
<obo:IAO_0000119>Suvarna Nadendla</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1243</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-LINCS</obo:IAO_0000234>
<rdfs:label>kinase inhibitor assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002963 -->
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<obo:IAO_0000111>KINOMEscan assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A type of proprietary kinase inhibitor assay that and employs a panel of kinases against which one can test compounds for their selectivity and potency in interactions with kinases, without the need to add ATP to the reactions.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000119>url:https://www.discoverx.com/technologies-platforms/competitive-binding-technology/kinomescan-technology-platform</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1243</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-LINCS</obo:IAO_0000234>
<rdfs:label>KINOMEscan assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002964 -->
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<obo:IAO_0000111>KiNativ assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A type of proprietary in situ kinase inhibitor assay that employs biotinylated acyl phosphates of ATP and ADP.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000119>url:https://www.kinativ.com/technology.html</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1243</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-LINCS</obo:IAO_0000234>
<rdfs:label>KiNativ assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0002965 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002965">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000424"/>
<obo:IAO_0000111>landmark transcript profiling assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A type of transcription profiling assay in which a set of landmark transcripts that have been determined to provide a comprehensive profile of cell activity, plus numerous steady-state controls, are assayed via ligation-mediated amplification followed by capture on fluorescently labeled microspheres followed by detection of fluorescence.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>L1000 mRNA profiling assay</obo:IAO_0000118>
<obo:IAO_0000119>PMID:29195078</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1243</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-LINCS</obo:IAO_0000234>
<rdfs:label>landmark transcript profiling assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002966 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002966">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001977"/>
<obo:IAO_0000111>microenvironment microarray assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A type of cytometry assay where cells are incubated for three days with a standardized set of extracellular matrix proteins in combination with various ligands creating varying microenvironment perterbations for the cells. Immunofluorescent imaging of cells is used to measure features such as morphology, metabolism, cell cycle, and nuclear activity.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>MEMA assay</obo:IAO_0000118>
<obo:IAO_0000119>PMID:29199020</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1243</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-LINCS</obo:IAO_0000234>
<rdfs:label>microenvironment microarray assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002967 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002967">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000854"/>
<obo:IAO_0000111>microwestern meso-scale quantitative western blot assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A western blot assay that provides a high-throughput, sensitive, and quantitative measurement of proteins from numerous samples via an array of small western blots on a single sheet of nitrocellulose.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000119>PMID:28092050</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1243</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-LINCS</obo:IAO_0000234>
<rdfs:label>microwestern meso-scale quantitative western blot assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002968 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002968">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000366"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000470"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003368"/>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>positive/negative ion switching metabolite profiling assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A type of metabolic profiling assay which employs a hybrid dual quadrupole linear ion trap mass spectrometer for steady-state profiling of endogenous polar metabolites from organic extractions from biological samples.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>positive/negative ion switching metabolomic assay</obo:IAO_0000118>
<obo:IAO_0000119>PMID:22498707</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1243</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-LINCS</obo:IAO_0000234>
<rdfs:label>positive/negative ion switching metabolite profiling assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002969 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002969">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002119"/>
<obo:IAO_0000111>cyclic immunofluoroescence assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A type of microscopy assay resulting in highly multiplexed immunofluorescence imaging through sequential rounds of imaging followed by fluorophore inactivation.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000119>PMID:27925668</obo:IAO_0000119>
<obo:IAO_0000119>PMID:29993362</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1243</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-LINCS</obo:IAO_0000234>
<rdfs:label>cyclic immunofluoroescence assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002970 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002970">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002953"/>
<obo:IAO_0000111>multiplex bead-based protein state immunoassay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A type of protein state assay in which antibodies attached to different colored beads and fluorescent reporter dye labels are used in a multiplexed mixture to assay for proteins in specific states.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000119>url:https://www.bio-rad.com/en-us/applications-technologies/multiplex-immunoassays?ID=LUSM0E8UU</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1243</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-LINCS</obo:IAO_0000234>
<rdfs:label>multiplex bead-based protein state immunoassay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002971 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002971">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002783"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0006538"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>endotracheal tube specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen that derives from a biofilm that forms on the inner surface of an endotracheal tube while the tube is in the trachea. The specimen is collected upon removal of the tube from the trachea.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins ORCID:0000-0001-6595-0902</obo:IAO_0000117>
<obo:IAO_0000119>https://bmcpulmmed.biomedcentral.com/articles/10.1186/s12890-019-0926-3</obo:IAO_0000119>
<rdfs:label>endotracheal tube specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002972 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002972">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002781"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0006538"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002785"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>endotracheal aspirate specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen that derives from a biofilm that forms on the inner surface of an endotracheal tube while the tube is in the trachea. The specimen is collected by suction without removing the tube.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins ORCID:0000-0001-6595-0902</obo:IAO_0000117>
<obo:IAO_0000119>https://bmcpulmmed.biomedcentral.com/articles/10.1186/s12890-019-0926-3</obo:IAO_0000119>
<rdfs:label>endotracheal aspirate specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002975 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002975">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000973"/>
<obo:IAO_0000111>input protein sequence start site</obo:IAO_0000111>
<obo:IAO_0000112>When a new genome is sequenced, the start sites of proteins are identified by comparing the new sequence to that of a reference sequence in a database. The first amino acid of a protein sequence being analyzed is the input protein sequence start site.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The position of the first amino acid in a protein sequence being analyzed (input protein sequence).</obo:IAO_0000115>
<obo:IAO_0000117>Emma Griffiths</obo:IAO_0000117>
<obo:IAO_0000118>input protein start</obo:IAO_0000118>
<obo:IAO_0000118>query protein start site</obo:IAO_0000118>
<obo:IAO_0000119>Emma Griffiths</obo:IAO_0000119>
<rdfs:label>input protein sequence start site</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002976 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002976">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000973"/>
<obo:IAO_0000111>input protein sequence stop site</obo:IAO_0000111>
<obo:IAO_0000112>When a new genome is sequenced, the termination sites of proteins are identified by comparing the new sequence to that of a reference sequence in a database. The last amino acid of a protein sequence being analyzed is the input protein sequence stop site.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The position of the last amino acid in a protein sequence being analyzed (input protein sequence).</obo:IAO_0000115>
<obo:IAO_0000117>Emma Griffiths</obo:IAO_0000117>
<obo:IAO_0000118>input protein stop</obo:IAO_0000118>
<obo:IAO_0000118>query protein stop site</obo:IAO_0000118>
<obo:IAO_0000119>Emma Griffiths</obo:IAO_0000119>
<rdfs:label>input protein sequence stop site</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002977 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002977">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000973"/>
<obo:IAO_0000111>input gene sequence start site</obo:IAO_0000111>
<obo:IAO_0000112>When a new genome is sequenced, the start sites of genes are identified by comparing the new sequence to that of a reference sequence in a database. The first nucelotide of a gene sequence being analyzed is the input gene sequence start site.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The position of the first nucleotide in a gene sequence being analyzed (input gene sequence).</obo:IAO_0000115>
<obo:IAO_0000117>Emma Griffiths</obo:IAO_0000117>
<obo:IAO_0000118>input gene start</obo:IAO_0000118>
<obo:IAO_0000118>query gene start site</obo:IAO_0000118>
<obo:IAO_0000119>Emma Griffiths</obo:IAO_0000119>
<rdfs:label>input gene sequence start site</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002978 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002978">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000973"/>
<obo:IAO_0000111>input gene sequence stop site</obo:IAO_0000111>
<obo:IAO_0000112>When a new genome is sequenced, the termination sites of genes are identified by comparing the new sequence to that of a reference sequence in a database. The last nucelotide of a gene sequence being analyzed is the input gene sequence stop site.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The position of the last nucelotide in a gene sequence being analyzed (input gene sequence).</obo:IAO_0000115>
<obo:IAO_0000117>Emma Griffiths</obo:IAO_0000117>
<obo:IAO_0000118>input gene stop</obo:IAO_0000118>
<obo:IAO_0000118>query gene stop site</obo:IAO_0000118>
<obo:IAO_0000119>Emma Griffiths</obo:IAO_0000119>
<rdfs:label>input gene sequence stop site</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002979 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002979">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000973"/>
<obo:IAO_0000111>reference protein sequence start site</obo:IAO_0000111>
<obo:IAO_0000112>When a new genome is sequenced, the start sites of proteins are identified by comparing the new sequence to that of a reference sequence in a database. The first amino acid of a protein sequence being used for comparison is the reference protein sequence start site.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The position of the first amino acid in a reference protein sequence (sequence being used for comparison).</obo:IAO_0000115>
<obo:IAO_0000117>Emma Griffiths</obo:IAO_0000117>
<obo:IAO_0000118>reference protein start</obo:IAO_0000118>
<obo:IAO_0000118>subject protein start site</obo:IAO_0000118>
<obo:IAO_0000119>Emma Griffiths</obo:IAO_0000119>
<rdfs:label>reference protein sequence start site</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002980 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002980">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000973"/>
<obo:IAO_0000111>reference protein sequence stop site</obo:IAO_0000111>
<obo:IAO_0000112>When a new genome is sequenced, the termination sites of proteins are identified by comparing the new sequence to that of a reference sequence in a database. The last amino acid of a protein sequence used for comparison is the reference protein sequence stop site.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The position of the last amino acid in a reference protein sequence (sequence being used for comparison).</obo:IAO_0000115>
<obo:IAO_0000117>Emma Griffiths</obo:IAO_0000117>
<obo:IAO_0000118>reference protein stop</obo:IAO_0000118>
<obo:IAO_0000118>subject protein stop site</obo:IAO_0000118>
<obo:IAO_0000119>Emma Griffiths</obo:IAO_0000119>
<rdfs:label>reference protein sequence stop site</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002981 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002981">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000973"/>
<obo:IAO_0000111>reference gene sequence start site</obo:IAO_0000111>
<obo:IAO_0000112>When a new genome is sequenced, the start sites of genes are identified by comparing the new sequence to that of a reference sequence in a database. The first nucelotide of a gene sequence used for comparison is the reference gene sequence start site.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The position of the first nucleotide in a reference gene sequence (sequence being used for comparison).</obo:IAO_0000115>
<obo:IAO_0000117>Emma Griffiths</obo:IAO_0000117>
<obo:IAO_0000118>reference gene start</obo:IAO_0000118>
<obo:IAO_0000118>subject gene start site</obo:IAO_0000118>
<obo:IAO_0000119>Emma Griffiths</obo:IAO_0000119>
<rdfs:label>reference gene sequence start site</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002982 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002982">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000973"/>
<obo:IAO_0000111>reference gene sequence stop site</obo:IAO_0000111>
<obo:IAO_0000112>When a new genome is sequenced, the termination sites of genes are identified by comparing the new sequence to that of a reference sequence in a database. The last nucelotide of a gene sequence used for comparison is the reference gene sequence stop site.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The position of the last nucelotide in a reference sequence (sequence being used for comparison).</obo:IAO_0000115>
<obo:IAO_0000117>Emma Griffiths</obo:IAO_0000117>
<obo:IAO_0000118>reference gene stop</obo:IAO_0000118>
<obo:IAO_0000118>subject gene stop site</obo:IAO_0000118>
<obo:IAO_0000119>Emma Griffiths</obo:IAO_0000119>
<rdfs:label>reference gene sequence stop site</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002983 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002983">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000408"/>
<obo:IAO_0000111>altitude measurement datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A length measurement datum between a point at sea or ground level and some point above it.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>Adapted from https://www.merriam-webster.com/dictionary/altitude</obo:IAO_0000119>
<rdfs:label>altitude measurement datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002984 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002984">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002440"/>
<obo:IAO_0000111>capture Hi-C assay</obo:IAO_0000111>
<obo:IAO_0000112>PMID:29979818 Chromosome conformation capture (3C), coupled with next-generation sequencing (Hi-C), provides a means for deciphering not only the principles underlying genome folding and architecture, but more broadly, the role 3D chromatin structure plays in gene regulation and the replication and repair of DNA.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A Hi-C assay in which a selection step is performed on ligated fragments in order to enrich for ligation products containing specific regions of interest.</obo:IAO_0000115>
<obo:IAO_0000117>Bonita Lam</obo:IAO_0000117>
<obo:IAO_0000118>cHi-C</obo:IAO_0000118>
<obo:IAO_0000119>PMID:29979818</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1251</obo:IAO_0000233>
<rdfs:label>capture Hi-C assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002985 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002985">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000185"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000566"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000566"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000059"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0003332"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0003330"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>magnetic resonance imaging assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An imaging assay in which nuclear magnetic resonance is used to produce information about the interior structure and composition of an input material entity.</obo:IAO_0000115>
<obo:IAO_0000117>Alexander D. Bartnik, ORCID:0000-0001-9676-7377</obo:IAO_0000117>
<obo:IAO_0000117>Alexander D. Diehl, ORCID:0000-0001-9990-8331</obo:IAO_0000117>
<obo:IAO_0000117>Lauren M. Wishnie, ORCID:0000-0002-7245-3450</obo:IAO_0000117>
<obo:IAO_0000117>Lucas M. Serra, ORCID:0000-0002-2104-0568</obo:IAO_0000117>
<obo:IAO_0000117>Mackenzie T. Smith, ORCID:0000-0002-9821-4132</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>William D. Duncan, ORCID:0000-0001-9625-1899</obo:IAO_0000117>
<obo:IAO_0000118>MRI</obo:IAO_0000118>
<obo:IAO_0000119>url:https://en.wikipedia.org/wiki/Magnetic_resonance_imaging</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1290</obo:IAO_0000233>
<rdfs:label>magnetic resonance imaging assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002986 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002986">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000185"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000982"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000982"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>computed tomography imaging assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An imaging assay that uses a series of X-ray images to produce information about the interior structure and composition of an input material entity.</obo:IAO_0000115>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000118>CAT scan</obo:IAO_0000118>
<obo:IAO_0000118>CT scan</obo:IAO_0000118>
<obo:IAO_0000118>computed tomography scan</obo:IAO_0000118>
<obo:IAO_0000119>url:https://www.mayoclinic.org/tests-procedures/ct-scan/about/pac-20393675</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1290</obo:IAO_0000233>
<rdfs:label>computed tomography imaging assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002987 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002987">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000185"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000933"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000933"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>positron emission tomography imaging assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An imaging assay in which positron-emitting radionuclides are used to visualize functional processes of an input material entity.</obo:IAO_0000115>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000118>PET scan</obo:IAO_0000118>
<obo:IAO_0000118>positron emission tomography scan</obo:IAO_0000118>
<obo:IAO_0000119>url:https://en.wikipedia.org/wiki/Positron_emission_tomography</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1290</obo:IAO_0000233>
<rdfs:label>positron emission tomography imaging assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002988 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002988">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000416"/>
<obo:IAO_0000111>duration of specimen collection</obo:IAO_0000111>
<obo:IAO_0000112>Specimen collection duration of 3 nights that a trap is set out for collection of mosquitoes. Urine collected over a 24 hour period of specimen collection duration.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A time measurement datum that is the count of collection cycles over which a specimen collection process occurs.</obo:IAO_0000115>
<obo:IAO_0000118>specimen collection duration</obo:IAO_0000118>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<rdfs:label>specimen collection duration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002989 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002989">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000245"/>
</owl:unionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000018"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000111>material supplier</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A person or organization that provides material supplies to other people or organizations.</obo:IAO_0000115>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1289</obo:IAO_0000233>
<rdfs:label>material supplier</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002990 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002990">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600047"/>
<obo:IAO_0000111>T cell receptor repertoire sequencing assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A sequencing assay that determines the sequences of DNA or RNA molecules that encode the repertoire of T cell receptors within an input sample.</obo:IAO_0000115>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000118>TCR repertoire sequencing assay</obo:IAO_0000118>
<obo:IAO_0000118>bulk TCR assay</obo:IAO_0000118>
<obo:IAO_0000119>doi:10.1186/s12896-017-0379-9</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1307</obo:IAO_0000233>
<rdfs:label>T cell receptor repertoire sequencing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002991 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002991">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600047"/>
<obo:IAO_0000111>B cell receptor repertoire sequencing assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A sequencing assay that determines the sequence of a DNA or RNA molecules that encode the repertoire of B cell receptors within an input sample.</obo:IAO_0000115>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000118>Antibody repertoire sequencing assay</obo:IAO_0000118>
<obo:IAO_0000118>BCR repertoire sequencing assay</obo:IAO_0000118>
<obo:IAO_0000118>bulk BCR assay</obo:IAO_0000118>
<obo:IAO_0000119>doi:10.1186/s12896-017-0379-9</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1307</obo:IAO_0000233>
<rdfs:label>B cell receptor repertoire sequencing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002992 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002992">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
<obo:IAO_0000111>prevalence of pathogen in specimens</obo:IAO_0000111>
<obo:IAO_0000112>prevalence of Plasmodium falciparum in Mosquito samples assayed by PCR</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A data item that is the frequency of detection of a specified pathogenic organism in collected specimens.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000118>prevalence of pathogen</obo:IAO_0000118>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<rdfs:label>prevalence of pathogen in specimens</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002993 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002993">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
<obo:IAO_0000111>prevalence of blood meal specimens from a host organism</obo:IAO_0000111>
<obo:IAO_0000112>prevalence of blood meal host organism in specimens measured as % of blood meal specimens collected from mosquitoes that had human blood as a meal.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A data item that is the frequency of blood whose source is from a specified host organism in collected blood meal specimens.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000118>host blood index</obo:IAO_0000118>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<rdfs:label>prevalence of blood meal specimens from a host organism</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002994 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002994">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
<obo:IAO_0000111>presence of blood from host organism in blood meal specimen</obo:IAO_0000111>
<obo:IAO_0000112>presence of blood meal host organism indicated by boolean values of yes or no.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A data item that indicates whether blood in a blood meal specimen came from a specified host organism.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000118>presence of blood meal host organism</obo:IAO_0000118>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<rdfs:label>presence of blood from host organism in blood meal specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002995 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002995">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100026"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002996"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>blood meal source organism</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An organism that is the source of a blood meal.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000118>blood meal host organism</obo:IAO_0000118>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<rdfs:label>blood meal source organism</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002996 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002996">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<obo:IAO_0000111>blood meal source role</obo:IAO_0000111>
<obo:IAO_0000112>A mosquito feeds on a human whereby the human acquires the blood meal source role for the mosquito blood meal.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A role borne by an organism that is gained during a process in which another organism ingests blood as food from the organism.</obo:IAO_0000115>
<obo:IAO_0000116>Will deprecate this term in VEuPathDB ontology once in OBI.</obo:IAO_0000116>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000119>http://purl.obolibrary.org/obo/EUPATH_0000791</obo:IAO_0000119>
<rdfs:label>blood meal source role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002997 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002997">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<obo:IAO_0000111>arthropod attractor role</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A role of a material entity realized in drawing an arthropod in the direction of the material.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>attractant</obo:IAO_0000118>
<obo:IAO_0000119>IRO:0000034</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1302</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>arthropod attractor role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002998 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002998">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002913"/>
<obo:IAO_0000111>arthropod collection process with automated identification</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An arthropod specimen collection process that involves a device that produces data specifying the types of arthropod collected.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1302</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>arthropod collection process with automated identification</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002999 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002999">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002913"/>
<obo:IAO_0000111>gravid female arthropod specimen collection process</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An arthropod specimen collection process that has the objective of collecting gravid female arthropods.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1302</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>gravid female arthropod specimen collection process</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003000 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003000">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002913"/>
<obo:IAO_0000111>resting flight-capable arthropod specimen collection process</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An arthropod specimen collection process that occurs while an arthropod that is capable of flight is resting outdoors during a period of inactivity.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VSMO:0000514</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1302</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>resting flight-capable arthropod specimen collection process</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003001 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003001">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002912"/>
<obo:IAO_0000111>daytime arthropod specimen collection by aspiration</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An arthropod specimen collection by aspiration that occurs in the daytime.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1302</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>daytime arthropod specimen collection by aspiration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003002 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003002">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002912"/>
<obo:IAO_0000111>arthropod resting in human house specimen collection by aspiration</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An arthropod specimen collection by aspiration that catches specimens resting inside a human house.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1302</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>arthropod resting in human house specimen collection by aspiration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003003 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003003">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002904"/>
<obo:IAO_0000111>landing arthropod specimen collection process</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An arthropod specimen collection process that occurs while the arthropods land on a surface.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>collection of landing insects</obo:IAO_0000118>
<obo:IAO_0000119>VSMO:0001457</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1302</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>landing arthropod specimen collection process</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003004 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003004">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002904"/>
<obo:IAO_0000111>flying adult arthropod collection process by passive interception</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An adult arthropod specimen collection process that has the objective of collecting arthropods capable of flight, through the use of a barrier trap.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1302</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>flying adult arthropod collection process by passive interception</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003005 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003005">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<obo:IAO_0000111>device for collection of resting adult arthropods</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that is designed to provide a solid surface that is attractive to an arthropod as a place to rest during a period of inactivity.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VSMO:0001355</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1302</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>device for collection of resting adult arthropods</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003006 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003006">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<obo:IAO_0000111>well net for arthropod immatures</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A device that is designed for the collection of arthropod larvae or pupae from water and consists of a conical net.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1302</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>well net for arthropod immatures</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003007 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003007">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002920"/>
<obo:IAO_0000111>arthropod trap containing small non-human animal bait</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An arthropod trap that uses as attractant an animal that is not human and is the size of a chicken or smaller.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>trap containing small non-human animal bait</obo:IAO_0000118>
<obo:IAO_0000119>VSMO:0001595</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1302</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>arthropod trap containing small non-human animal bait</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003008 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003008">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002920"/>
<obo:IAO_0000111>trap for emerging adult arthropods</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An arthropod trap that is designed to trap an arthropod as it emerges from water at the beginning of its adult stage.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>American Midland Naturalist, Vol. 97, No. 2 (Apr., 1977), pp. 381-389</obo:IAO_0000119>
<obo:IAO_0000119>VSMO:0001352</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1302</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>trap for emerging adult arthropods</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003009 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003009">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0070288"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>ferritin assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures ferritin</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton, ORCID:0000-0001-5139-5557</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>ferritin assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003010 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003010">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0005577"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>fibrinogen assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures fibrinogen</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton, ORCID:0000-0001-5139-5558</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>fibrinogen assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003011 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003011">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_24875"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_24875"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<obo:IAO_0000111>iron assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of iron</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton, ORCID:0000-0001-5139-5559</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>iron assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003012 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003012">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_39124"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_39124"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<obo:IAO_0000111>ionized calcium assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of ionized calcium</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton, ORCID:0000-0001-5139-5561</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>ionized calcium assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003013 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003013">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000016261"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000016261"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100023"/>
<obo:IAO_0000111>transferrin assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of transferrin</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton, ORCID:0000-0001-5139-5562</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>transferrin assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003014 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003014">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_27226"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_27226"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<obo:IAO_0000111>uric acid assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of uric acid</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton, ORCID:0000-0001-5139-5563</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>uric acid assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003015 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003015">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_166899"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_166899"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<obo:IAO_0000111>globulin assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of globulin</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton, ORCID:0000-0001-5139-5564</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>globulin assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003016 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003016">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001977"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0002193"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001977"/>
<obo:IAO_0000111>myelocyte assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the abundance and/or characteristics of myelocytes</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton, ORCID:0000-0001-5139-5565</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>myelocyte assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003017 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003017">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001977"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0002192"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001977"/>
<obo:IAO_0000111>metamyelocyte assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the abundance and/or characteristics of metamyelocytes</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton, ORCID:0000-0001-5139-5566</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>metamyelocyte assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003018 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003018">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001977"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000232"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001977"/>
<obo:IAO_0000111>hematocrit assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the proportion of red blood cells</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton, ORCID:0000-0001-5139-5567</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>hematocrit assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003019 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003019">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001977"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000836"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001977"/>
<obo:IAO_0000111>promyelocyte assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the abundance and/or characteristics of promyelocytes</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton, ORCID:0000-0001-5139-5568</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>promyelocyte assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003021 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003021">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001977"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000767"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001977"/>
<obo:IAO_0000111>basophil assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the abundance and/or characteristics of basophils</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton, ORCID:0000-0001-5139-5569</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>basophil assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003022 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001977"/>
<obo:IAO_0000111>neutrophil assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the abundance and/or characteristics of neutrophils</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton, ORCID:0000-0001-5139-5570</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>neutrophil assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003023 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001977"/>
<obo:IAO_0000111>eosinophil assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the abundance and/or characteristics of eosinophils</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton, ORCID:0000-0001-5139-5571</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>eosinophil assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003024 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001977"/>
<obo:IAO_0000111>lymphocyte assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the abundance and/or characteristics of lymphocytes</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton, ORCID:0000-0001-5139-5572</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>lymphocyte assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003025 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003025">
<owl:equivalentClass>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001977"/>
<obo:IAO_0000111>monocyte assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the abundance and/or characteristics of monocytes</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton, ORCID:0000-0001-5139-5573</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>monocyte assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003026 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003026">
<owl:equivalentClass>
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</owl:Class>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001977"/>
<obo:IAO_0000111>reticulocyte assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the abundance and/or characteristics of reticulocytes</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton, ORCID:0000-0001-5139-5574</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>reticulocyte assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003027 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003027">
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</owl:someValuesFrom>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001977"/>
<obo:IAO_0000111>macrophage assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the abundance and/or characteristics of macrophages</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton, ORCID:0000-0001-5139-5577</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>macrophage assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003028 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003028">
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000233"/>
</owl:Restriction>
</owl:someValuesFrom>
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</owl:Class>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001977"/>
<obo:IAO_0000111>platelet assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the abundance and/or characteristics of platelets</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton, ORCID:0000-0001-5139-5578</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>platelet assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003029 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003029">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
<rdfs:subClassOf>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001960"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>barcode target locus role</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An evaluant role that is realized in a taxonomic diversity assessment by targeted gene survey involving sequencing a small defined region of genome amplified by PCR.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert https://orcid.org/0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1325</obo:IAO_0000233>
<rdfs:label>barcode target locus role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003030 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003030">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33696"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000053"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000405"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>oligonucleotide primer set</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A processed material that consists of oligonucleotides that bear a primer role.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert https://orcid.org/0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1325</obo:IAO_0000233>
<rdfs:label>oligonucleotide primer set</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003031 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003031">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002692"/>
<obo:IAO_0000111>fluorogenic PCR assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A polymerase chain reaction assay that uses target specific probes labeled with fluorogenic chromophores.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>TaqMan</obo:IAO_0000118>
<obo:IAO_0000119>MIRO:20000102</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1320</obo:IAO_0000233>
<rdfs:label>fluorogenic PCR assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003032 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003032">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000435"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002692"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000415"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>genotyping by PCR assay</obo:IAO_0000111>
<obo:IAO_0000112>genotyping by PCR assay to identify microsatellites, chromosomal inversions and targeted assays of known resistance loci.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A genotyping assay that uses polymerase chain reaction.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000117>Jie Zheng, ORCID:0000-0002-2999-0103</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1348</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>genotyping by PCR assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003033 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003033">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000626"/>
<obo:IAO_0000111>cleavage under targets and release using nuclease assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A type of DNA sequencing assay employing in situ chromatin profiling in which antibody-targeted controlled cleavage by micrococcal nuclease releases specific protein-DNA complexes into the the supernatant for sequencing.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>CUT&RUN assay</obo:IAO_0000118>
<obo:IAO_0000119>url:https://elifesciences.org/articles/21856</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1192</obo:IAO_0000233>
<obo:IAO_0000234>bonitalam</obo:IAO_0000234>
<rdfs:label>cleavage under targets and release using nuclease assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003034 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003034">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000626"/>
<obo:IAO_0000111>cleavage under targets and tagmentation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A type of DNA sequencing assay employing in situ chromatin profiling in which a chromatin protein is bound in situ by a specific antibody, which then tethers to a protein A-Tn5 hyperactive transposase fusion protein (pA-Tn5) loaded with sequence adapters. Activation of pA-Tn5 results in factor-targeted tagmentation, generating fragments ready for PCR enrichment and DNA sequencing.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>CUT&Tag assay</obo:IAO_0000118>
<obo:IAO_0000119>url:https://www.nature.com/articles/s41467-019-09982-5</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1192</obo:IAO_0000233>
<obo:IAO_0000234>bonitalam</obo:IAO_0000234>
<rdfs:label>cleavage under targets and tagmentation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003035 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003035">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002441"/>
<obo:IAO_0000111>coma severity assay</obo:IAO_0000111>
<obo:IAO_0000112>Examining a patient and grading their coma status on the Blantyre or Glasgow coma scale.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A physical examination of an organism that has the objective to determine the severity of coma in a patient.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1357</obo:IAO_0000233>
<obo:IAO_0000234>John Judkins</obo:IAO_0000234>
<rdfs:label>coma severity assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003036 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003036">
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</owl:Restriction>
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</owl:Class>
</owl:someValuesFrom>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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</owl:Restriction>
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</rdfs:subClassOf>
<obo:IAO_0000111>Plasmodium gametocyte detection assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that detects Plasmodium gametocytes in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1322</obo:IAO_0000233>
<rdfs:label>Plasmodium gametocyte detection assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003037 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003037">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003038"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf>
<owl:Class>
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<obo:IAO_0000111>malaria rapid diagnosis assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that is quick and easy in the diagnosis of malaria by detecting evidence of malaria parasites (antigens) in human blood.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000118>malaria rapid diagnosis test</obo:IAO_0000118>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1322</obo:IAO_0000233>
<rdfs:label>malaria rapid diagnosis assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003038 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003038">
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000232"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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</owl:Restriction>
</owl:intersectionOf>
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</rdfs:subClassOf>
<obo:IAO_0000111>parasite detection assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that detects parasite in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1322</obo:IAO_0000233>
<rdfs:label>parasite detection assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003039 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003039">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003237"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003498"/>
<rdfs:subClassOf>
<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002503"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
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</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002444"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>feces microbiology assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An organism detection assay that detects microorganisms in a feces specimen.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>stool test for microorganisms</obo:IAO_0000118>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1322</obo:IAO_0000233>
<rdfs:label>feces microbiology assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003040 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003040">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
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<owl:Class>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000655"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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<owl:Class>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>blood assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that has a blood specimen as evaulant.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1322</obo:IAO_0000233>
<rdfs:label>blood assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003041 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003041">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003038"/>
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<rdfs:subClassOf>
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</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
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<obo:IAO_0000111>falcivax rapid diagnostic test</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A parasite detection assay that can quickly establish the diagnosis of P. falciparum or P. vivax malaria infection by detecting the antigens in a person's blood.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1322</obo:IAO_0000233>
<rdfs:label>falcivax rapid diagnostic test</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003042 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003042">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003038"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000655"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
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</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>optimal-IT rapid diagnostic test</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A parasite detection assay that is rapid, sensitive, and able to differentiate between P. falciparum and other malaria parasites.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1322</obo:IAO_0000233>
<rdfs:label>optimal-IT rapid diagnostic test</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003043 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003043">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000651"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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</owl:Restriction>
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</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>urine assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that has a urine specimen as evaluant.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1322</obo:IAO_0000233>
<rdfs:label>urine assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003044 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003044">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003045"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002692"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003368"/>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>parasite species identification by PCR assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A parasite detection by PCR assay that identifies the species of parasite.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1322</obo:IAO_0000233>
<rdfs:label>parasite species identification by PCR assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003045 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003045">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002692"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003038"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000415"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002692"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003368"/>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>parasite detection by PCR assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A parasite detection assay that uses PCR.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1322</obo:IAO_0000233>
<rdfs:label>parasite detection by PCR assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003046 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003046">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002920"/>
<obo:IAO_0000111>free-standing window trap</obo:IAO_0000111>
<obo:IAO_0000112>Jonsson developed a free-standing window trap consisting of a 16 x 20-cm perspex box, 16 cm high and divided in the middle by a 20 x 36-cm sheet of perspex (window). The two compartments of the box are filled to a depth of about 12 cm with 4-6% formalin containing a few drops of detergent; in winter ethylene glycol can be added to prevent freezing. One or two holes drilled in one side of the box at 12 cm and covered with fine netting prevent the trap overflowing after heavy rain. Traps are mounted on aluminium poles. Flying insects on hitting the transparent vertical plastic window fall into the formalin. The window trap may catch vectors that are seeking a host or moving for other purposes. [ISBN:9781402066658]</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An arthropod trap that consists of a transparent window placed in a box that holds a liquid solution deadly to arthropods. This trap is designed to stop an arthropod in flight, causing it to fall into the liquid and die.</obo:IAO_0000115>
<obo:IAO_0000117>VEuPathDB</obo:IAO_0000117>
<obo:IAO_0000119>VSMO:0001649</obo:IAO_0000119>
<rdfs:label>free-standing window trap</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003048 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003048">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
<owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/OBI_0002903"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>BG-lure scent dispenser</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device manufactured by BioGents that is designed for operation with the BG-Sentinel trap and releases an attractant that mimics the scent of human skin.</obo:IAO_0000115>
<obo:IAO_0000117>VEuPathDB</obo:IAO_0000117>
<obo:IAO_0000118>BG-lure</obo:IAO_0000118>
<obo:IAO_0000119>IRO:0001060</obo:IAO_0000119>
<rdfs:label>BG-lure scent dispenser</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003049 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003049">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<obo:IAO_0000111>hand-held sweep net</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that consists of a network of mesh and is designed to capture adult arthropods.</obo:IAO_0000115>
<obo:IAO_0000117>VEuPathDB</obo:IAO_0000117>
<obo:IAO_0000119>VSMO:0001522</obo:IAO_0000119>
<rdfs:label>hand-held sweep net</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003050 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003050">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002929"/>
<obo:IAO_0000111>Centers for Disease Control and Prevention gravid trap</obo:IAO_0000111>
<obo:IAO_0000112>The original trap CDC gravid trap (or gravid trap of Reiter) consists of a 3 inch diameter PVC inlet tube housing a 6 V motor, as used in CDC traps, on which is mounted a four-bladed 3 inch counter-clockwise fan. The inlet tube is clamped between two vertical wooden boards that fit over a black plastic box (18.5 x 14.0 x 6.5 inches). A plastic 12 inch long PVC chimney slots into the upper end of the inlet tube. The top half consists of three struts that fit into and support a netting collecting bag. For this the middle of the collecting bag is reinforced with a circular patch of denim cloth. The oviposition attractant is made by adding 1 lb of hay and 1 oz each of dried brewer's yeast and lactalbumen powder to 30 gallons of tap water. This infusion is allowed to mature for 5 days. This original gravid mosquito trap of Reiter suffers from certain limitations, namely up to 10% of the catch of adults is damaged by passing through the fan blades, and adults tend to die of desiccation. [ISBN:9781402066658]</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A gravid trap that consists of a pan holding a hay infusion, motorized fan, and collection bag. This trap is designed to attract gravid female arthropods to the infused material, which would serve as an oviposition medium, and then draw them into the bag with the current generated by the fan.</obo:IAO_0000115>
<obo:IAO_0000117>VEuPathDB</obo:IAO_0000117>
<obo:IAO_0000118>CDC gravid trap</obo:IAO_0000118>
<obo:IAO_0000119>VSMO:0001510</obo:IAO_0000119>
<rdfs:label>Centers for Disease Control and Prevention gravid trap</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003051 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003051">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002907"/>
<obo:IAO_0000111>egg specimen collection process</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An arthropod specimen collection process in which the arthropods are in the embryo stage.</obo:IAO_0000115>
<obo:IAO_0000117>VEuPath</obo:IAO_0000117>
<obo:IAO_0000118>collection of eggs</obo:IAO_0000118>
<obo:IAO_0000119>MIRO:30000049</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1322</obo:IAO_0000233>
<rdfs:label>egg specimen collection process</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003052 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003052">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002907"/>
<obo:IAO_0000111>larval specimen collection process</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An arthropod specimen collection process in which the arthropods are in the larval stage.</obo:IAO_0000115>
<obo:IAO_0000117>VEuPath</obo:IAO_0000117>
<obo:IAO_0000118>collection of larvae</obo:IAO_0000118>
<obo:IAO_0000119>MIRO:30000022</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1322</obo:IAO_0000233>
<rdfs:label>larval specimen collection process</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003053 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003053">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002907"/>
<obo:IAO_0000111>pupal specimen collection process</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An arthropod specimen collection process in which the arthropods are in the pupal stage.</obo:IAO_0000115>
<obo:IAO_0000117>VEuPath</obo:IAO_0000117>
<obo:IAO_0000118>collection of pupae</obo:IAO_0000118>
<obo:IAO_0000119>MIRO:30000050</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1322</obo:IAO_0000233>
<rdfs:label>pupal specimen collection process</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003054 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003054">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000655"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000178"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>blood specimen in vacutainer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A blood specimen that is located in a vacutainer.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>Vacutainer sample</obo:IAO_0000118>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<rdfs:label>blood specimen in vacutainer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003055 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003055">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000655"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000178"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>blood specimen on filter paper</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A blood specimen that is located on a filter paper.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000118>Filter paper sample</obo:IAO_0000118>
<obo:IAO_0000119>Penn Group</obo:IAO_0000119>
<rdfs:label>blood specimen on filter paper</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003056 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003056">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000973"/>
<obo:IAO_0000111>proportion mapped reads</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A sequence datum that is the specified output of a read mapping and is the ratio of the count of mapped reads to the total count of reads.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<rdfs:label>proportion mapped reads</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003057 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003057">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600007"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000319"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IDO_0000562"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>antibiotic administration process</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Administering substance in vivo where an antibiotic substance is administered to a living organism.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Cristian Cocos</obo:IAO_0000117>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>Penn Group</obo:IAO_0000119>
<rdfs:label>antibiotic administration process</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003063 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003063">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
<obo:IAO_0000111>insecticide resistance datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A data item that is about resistance to an insecticide.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<rdfs:label>insecticide resistance datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003064 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003064">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000027"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0003498"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
<obo:IAO_0000111>organism detection datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A data item that is the specified output of an organism detection assay.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<rdfs:label>organism detection datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003066 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003066">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000401"/>
<obo:IAO_0000111>easting coordinate measurement datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A one dimensional Cartesian spatial coordinate datum that is the eastward component of a distance from a point on a map projection.</obo:IAO_0000115>
<obo:IAO_0000116>Easting and northing coordinates are commonly measured in meters from a horizontal datum.</obo:IAO_0000116>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Grid_reference_system</obo:IAO_0000119>
<rdfs:label>easting coordinate measurement datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003067 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003067">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000401"/>
<obo:IAO_0000111>northing coordinate measurement datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A one dimensional Cartesian spatial coordinate datum that is the northward component of a distance from a point on a map projection.</obo:IAO_0000115>
<obo:IAO_0000116>Easting and northing coordinates are commonly measured in meters from a horizontal datum.</obo:IAO_0000116>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Grid_reference_system</obo:IAO_0000119>
<rdfs:label>northing coordinate measurement datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003068 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003068">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000245"/>
<obo:IAO_0000111>clinical study center</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Organization that undertakes a clinical study at some point in time.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Cristian Cocos</obo:IAO_0000117>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>Penn Group</obo:IAO_0000119>
<rdfs:label>clinical study center</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003069 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003069">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000272"/>
<obo:IAO_0000111>sequencing protocol</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A protocol that, when concretized, is realized in an assay that uses chemical or biological means to infer the sequence of a biomaterial.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<rdfs:label>sequencing protocol</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003070 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003070">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000272"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000684"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>specimen collection protocol</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A protocol that specifies processes to fulfill a specimen collection objective.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<rdfs:label>specimen collection protocol</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003071 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003071">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000028"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000219"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000097"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000028"/>
<obo:IAO_0000111>participant identifier</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A symbol that denotes a participant under investigation.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<rdfs:label>participant identifier</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003072 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003072">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003079"/>
<obo:IAO_0000111>axillary temperature measurement datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A temperature measurement datum that is about an axilla.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<rdfs:label>axillary temperature measurement datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003073 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003073">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003079"/>
<obo:IAO_0000111>organismal body temperature measurement datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A temperature measurement datum that is about an organism.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>Penn Group</obo:IAO_0000119>
<rdfs:label>organismal body temperature measurement datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003074 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003074">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000300"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000219"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>common name of organism</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A textual entity refers to a taxon or organism that is based on the normal language of everyday life; this kind of name is often contrasted with the scientific name for the same organism, which is Latinized.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Common_name</obo:IAO_0000119>
<rdfs:label>common name of organism</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003075 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003075">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001169"/>
<obo:IAO_0000111>age since birth at time of enrollment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An age since birth measurement datum at the time of subject enrollment.</obo:IAO_0000115>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>Penn Group</obo:IAO_0000119>
<rdfs:label>age since birth at time of enrollment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003076 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003076">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001169"/>
<obo:IAO_0000111>age since birth at time of visit</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An age since birth measurement datum at the time of a clinical visit.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Grant Dorsey</obo:IAO_0000117>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000117>Shon Cade</obo:IAO_0000117>
<obo:IAO_0000119>Penn Group</obo:IAO_0000119>
<rdfs:label>age since birth at time of visit</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003077 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003077">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
<obo:IAO_0000111>entomological data item</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A data item that is about a collection of insects.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>entomological measurement datum</obo:IAO_0000118>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<rdfs:label>entomological data item</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003079 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003079">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000032"/>
<obo:IAO_0000111>temperature measurement datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A scalar measurement datum that is the result of measuring temperature.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<rdfs:label>temperature measurement datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003080 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003080">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002140"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100026"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>organismal body temperature measurement assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that detects body temperature of an organism.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1322</obo:IAO_0000233>
<rdfs:label>organismal body temperature measurement assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003081 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003081">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000416"/>
<obo:IAO_0000111>extraction date</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A time measurement datum that specifies when some material was extracted from an input material.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, ORCID: 0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>FLU, VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1286</obo:IAO_0000233>
<rdfs:label>extraction date</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003082 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003082">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000416"/>
<obo:IAO_0000111>extraction duration time</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A time measurement datum that is the result of measuring the duration of an extraction process.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, ORCID: 0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>Meredith Keybl, Shane Babcock</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1286</obo:IAO_0000233>
<rdfs:label>extraction duration time</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003083 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003083">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001619"/>
<obo:IAO_0000111>specimen collection time post disease onset</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen collection time measurement datum that is the measure of a time when specimens are collected after the onset of disease in a host.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, ORCID: 0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>GROUP:FLU, Shane Babcock</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1286</obo:IAO_0000233>
<rdfs:label>specimen collection time post disease onset</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003084 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003084">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001619"/>
<obo:IAO_0000111>specimen collection time post infection</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen collection time measurement datum that is the measure of a time when specimens are collected after an infection starts.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, ORCID: 0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB, EUPATH:0000613</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1286</obo:IAO_0000233>
<rdfs:label>specimen collection time post infection</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003085 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003085">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000422"/>
<obo:IAO_0000111>laboratory postal address</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A postal address used as a directive to deliver something to a laboratory.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, ORCID: 0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000118>laboratory address</obo:IAO_0000118>
<obo:IAO_0000119>GROUP:FLU, Shane Babcock</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1286</obo:IAO_0000233>
<rdfs:label>laboratory postal address</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003086 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003086">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000181"/>
<obo:IAO_0000111>laboratory-based population</obo:IAO_0000111>
<obo:IAO_0000112>Refers to whether the mosquitoes used in the analysis of insecticide resistance were collected from an established strain or any other population kept in a laboratory under controlled conditions. (per MIRO_30000033)</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A population where the collection of individuals is located and maintained in a laboratory, research, or production facility.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, ORCID: 0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1370</obo:IAO_0000233>
<rdfs:label>laboratory-based population</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003087 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003087">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001501"/>
<obo:IAO_0000111>autofluorescence assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A fluorescence detection assay in which the light that is naturally emitted by a sample is visualized after excitation of the sample with light at a suitable wavelength.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>intrinsic fluorescence assay</obo:IAO_0000118>
<obo:IAO_0000119>PMID:25578980</obo:IAO_0000119>
<obo:IAO_0000119>url:https://en.wikipedia.org/wiki/Autofluorescence</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1393</obo:IAO_0000233>
<obo:IAO_0000234>CFDE</obo:IAO_0000234>
<rdfs:label>autofluorescence assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003088 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003088">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003087"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400169"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400169"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>autofluorescence microscopy assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An autofluorescence assay in which the light that is naturally emitted by a sample is visualized via microscopy after excitation of the sample with light at a suitable wavelength.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000119>PMID:25578980</obo:IAO_0000119>
<obo:IAO_0000119>url:https://en.wikipedia.org/wiki/Autofluorescence</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1394</obo:IAO_0000233>
<obo:IAO_0000234>CFDE</obo:IAO_0000234>
<rdfs:label>autofluorescence microscopy assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003089 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003089">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002039"/>
<obo:IAO_0000111>bulk assay for transposase-accessible chromatin using sequencing</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay for transposase-accessible chromatin using sequencing in which the sample that is sequenced is derived from a collection of cells, such as a tissue sample or entire cell culture, and therefore provides results representative of the aggregate of sample cells.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>bulk ATAC-seq</obo:IAO_0000118>
<obo:IAO_0000119>PMID:24097267</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1395</obo:IAO_0000233>
<obo:IAO_0000234>CFDE</obo:IAO_0000234>
<rdfs:label>bulk assay for transposase-accessible chromatin using sequencing</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003090 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003090">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001271"/>
<obo:IAO_0000111>bulk RNA-seq assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An RNA-seq assay in which the sample that is sequenced is derived from a collection of cells, such as a tissue sample or entire cell culture, and therefore provides results representative of the aggregate of sample cells.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000119>url:https://www.biostars.org/p/458516/</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1396</obo:IAO_0000233>
<obo:IAO_0000234>CFDE</obo:IAO_0000234>
<rdfs:label>bulk RNA-seq assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003091 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003091">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000185"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001501"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003368"/>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>multiplexed fluorescent antibody imaging assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An imaging assay in which multiple cycles consisting of fluorescent labeling, imaging, and fluorophor deactivation are used to detect multiple proteins and their locations in a given sample of tissues or cells.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000119>PMID:29993362</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1397</obo:IAO_0000233>
<obo:IAO_0000234>CFDE</obo:IAO_0000234>
<rdfs:label>multiplexed fluorescent antibody imaging assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003092 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003092">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003091"/>
<obo:IAO_0000111>Cell DIVE multiplexed imaging assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A multiplexed fluorescent antibody imaging assay that involves an iterative staining, imaging and dye inactivation workflow for over 60 biomarkers on a single fixed tissue section.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000119>url:https://cancerres.aacrjournals.org/content/80/16_Supplement/1448</obo:IAO_0000119>
<obo:IAO_0000119>url:https://www.cytivalifesciences.co.kr/wp-content/uploads/2020/07/Cell-DIVE-Tech-Info-Sheet-CY11898-09Apr20-DF.pdf</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1398</obo:IAO_0000233>
<obo:IAO_0000234>CFDE</obo:IAO_0000234>
<rdfs:label>Cell DIVE multiplexed imaging assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003093 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003093">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003091"/>
<obo:IAO_0000111>co-detection by indexing assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A multiplexed fluorescent antibody imaging assay that involves a highly multiplexed analysis of up to 40 proteins in a tissue using cyclic detection of DNA-indexed antibody panels.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>CODEX</obo:IAO_0000118>
<obo:IAO_0000119>url:https://www.scilifelab.se/facilities/co-detection-by-indexing-codex/</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1399</obo:IAO_0000233>
<obo:IAO_0000234>CFDE</obo:IAO_0000234>
<rdfs:label>co-detection by indexing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003094 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003094">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001686"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001501"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003368"/>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>fluorescence in-situ hybridization assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An in-situ hybridization assay in which fluorescently labeled molecules are used to localize specific DNA or RNA sequences.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>FISH</obo:IAO_0000118>
<obo:IAO_0000119>url:https://en.wikipedia.org/wiki/Fluorescence_in_situ_hybridization</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1400</obo:IAO_0000233>
<obo:IAO_0000234>CFDE</obo:IAO_0000234>
<rdfs:label>fluorescence in-situ hybridization assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003095 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003095">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000424"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003094"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<obo:IAO_0000111>decoding amplified targeted transcripts with fluorescence in situ hybridization assay</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A fluorescence in-situ hybridization assay which involves multiplex in situ digital quantification of targeted RNA transcripts in fresh or frozen tissue providing an understanding of the spatial organization of different cell types.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>DARTFISH</obo:IAO_0000118>
<obo:IAO_0000119>url:http://genome-tech.ucsd.edu/ZhangLab/index.php/data/tech-dev/</obo:IAO_0000119>
<obo:IAO_0000119>url:http://www.weizmann.ac.il/conferences/SCG2015/sites/conferences.SCG2015/files/scg_2015_abstractbook_online_version.pdf</obo:IAO_0000119>
<obo:IAO_0000119>url:https://escholarship.org/uc/item/5bq3128f</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1401</obo:IAO_0000233>
<obo:IAO_0000234>CFDE</obo:IAO_0000234>
<rdfs:label>decoding amplified targeted transcripts with fluorescence in situ hybridization assay</rdfs:label>
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<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>IMC</obo:IAO_0000118>
<obo:IAO_0000118>imaging CyTOF</obo:IAO_0000118>
<obo:IAO_0000119>PMID:31798587</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1403</obo:IAO_0000233>
<obo:IAO_0000234>CFDE</obo:IAO_0000234>
<rdfs:label>imaging mass cytometry assay</rdfs:label>
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<obo:IAO_0000115 xml:lang="en">A mass spectrometry assay where a sample mixture is first separated by liquid chromatography before being converted into ions which are characterized by using mass spectrometry based on their mass-to-charge ratio and relative abundance.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>LC-MS</obo:IAO_0000118>
<obo:IAO_0000119>CHMO:0000524</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1404</obo:IAO_0000233>
<obo:IAO_0000234>CFDE</obo:IAO_0000234>
<rdfs:label>liquid chromatography mass spectrometry assay</rdfs:label>
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<obo:IAO_0000111>lightsheet fluorescence microscopy assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A fluorescence microscopy that involves capturing of photons emitted by fluorophores excited with a thin sheet of laser light in a sample only in a relatively narrow plane by a detection objective oriented perpendicularly to the light sheet and imaged onto a detection device such as a CCD camera.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000119>url:https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/light-sheet-fluorescence-microscopy</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1405</obo:IAO_0000233>
<obo:IAO_0000234>CFDE</obo:IAO_0000234>
<rdfs:label>lightsheet fluorescence microscopy assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003099 -->
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<obo:IAO_0000111>matrix assisted laser desorption ionization imaging mass spectrometry assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A mass spectrometry assay that involves collection of spatially resolved mass spectra of a sample during microscopy where a pulse laser is used to produce both ionisation and vaporization. The sample is held in a matrix (such as dihydrobenzoic acid) to protect it from direct laser illumination and to separate the sample molecules. The spectra are used to visualise the spatial distribution of biomolecules by their molecular masses.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>MALDI-IMS</obo:IAO_0000118>
<obo:IAO_0000119>url:http://purl.obolibrary.org/obo/CHMO_0000054</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1406</obo:IAO_0000233>
<obo:IAO_0000234>CFDE</obo:IAO_0000234>
<rdfs:label>matrix assisted laser desorption ionization imaging mass spectrometry assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003100 -->
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<obo:IAO_0000111>multiplexed ion beam imaging assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry time of flight assay in which molecules of interest on or in cells are imaged through a system in which samples are labeled with multiple different rare-earth tagged antibodies. A primary ion beam is ued to rasterize sections under vacuum, releasing showers of secondary ions detected by cytometry time of flight mass spectrometry.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>MIBI</obo:IAO_0000118>
<obo:IAO_0000119>url:https://www.nature.com/articles/s41374-020-0417-4</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1407</obo:IAO_0000233>
<obo:IAO_0000234>CFDE</obo:IAO_0000234>
<rdfs:label>multiplexed ion beam imaging assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003101 -->
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<obo:IAO_0000111>nanospray desorption electrospray ionization assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A mass spectrometry assay that analyzes organic and biological molecules on a substrate by desorption of an analyte into a solvent bridge formed between two capillaries and the analysis surface. One capillary supplies solvent to create and maintain the bridge, while the second capillary transports the dissolved analyte from the bridge to the mass spectrometer. A high voltage applied between the inlet of mass spectrometer and the primary capillary creates a self-aspirating nanospray.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>NanoDESI</obo:IAO_0000118>
<obo:IAO_0000119>url:https://pubmed.ncbi.nlm.nih.gov/20593081/</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1408</obo:IAO_0000233>
<obo:IAO_0000234>CFDE</obo:IAO_0000234>
<rdfs:label>nanospray desorption electrospray ionization assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003102 -->
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<obo:IAO_0000111>nanodroplet processing in one pot for trace samples assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A protein expression profiling assay in which proteomics sample processing is performed in nanoliter volumes. Flow cytometry or laser microdissection is employed to isolate a small population or single cells into a nanoPOTS chip. Then, liquid chromatography mass spectrometry is used to measure the global protein expression.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>NanoPOTS</obo:IAO_0000118>
<obo:IAO_0000119>url:https://www.emsl.pnnl.gov/science/related-instrument/nanodroplet-processing-in-one-pot-for-trace-samples--nanopots-/1806</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1409</obo:IAO_0000233>
<obo:IAO_0000234>CFDE</obo:IAO_0000234>
<rdfs:label>nanodroplet processing in one pot for trace samples assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003103 -->
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<obo:IAO_0000111>periodic acid-Schiff staining assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A histological assay which is used on tissue samples to demonstrate the presence of carbohydrates and carbohydrate compounds such as polysaccharides, mucin, glycogen, or fungal cell wall components.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>PAS staining</obo:IAO_0000118>
<obo:IAO_0000119>url:https://microbenotes.com/periodic-acid-schiff-pas-staining/</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1410</obo:IAO_0000233>
<obo:IAO_0000234>CFDE</obo:IAO_0000234>
<rdfs:label>periodic acid-Schiff staining assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003104 -->
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<obo:IAO_0000111>single cell combinatorial indexing assay for transposase-accessessable chromatin using sequencing</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay for transposase-accessible chromatin that uses sequencing which involves single cell combinatorial indexing ('sci-') strategy where nucleic acids from each of many cells are uniquely tagged through several rounds of split-pool barcoding which enables identification of single cells without single cell isolation.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>sciATACseq</obo:IAO_0000118>
<obo:IAO_0000119>url:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158300/</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1411</obo:IAO_0000233>
<obo:IAO_0000234>CFDE</obo:IAO_0000234>
<rdfs:label>single cell combinatorial indexing assay for transposase-accessessable chromatin using sequencing</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003105 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002631"/>
<obo:IAO_0000111>single-cell combinatorial indexing RNA sequencing assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A single-cell RNA sequencing assay that involves single cell combinatorial indexing ('sci-') strategy to profile the transcriptomes of single cells or nuclei without single cell isolation.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>sciRNAseq</obo:IAO_0000118>
<obo:IAO_0000119>url:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894354/</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1412</obo:IAO_0000233>
<obo:IAO_0000234>CFDE</obo:IAO_0000234>
<rdfs:label>single-cell combinatorial indexing RNA sequencing assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003106 -->
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<obo:IAO_0000111>sequential fluorescence in-situ hybridization assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A fluorescence in-situ hybridization assay that involves ultra-resolution imaging of cell activity by targetting thousands of single molecules with fluorescent probes which find and hybridize with complementary DNA or RNA sequences in the tissue sample, thus enabling identification of those molecules directly in single cells with their spatial context preserved.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>seqFISH</obo:IAO_0000118>
<obo:IAO_0000119>url:https://spatial.caltech.edu/seqfish/</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1413</obo:IAO_0000233>
<obo:IAO_0000234>CFDE</obo:IAO_0000234>
<rdfs:label>sequential fluorescence in-situ hybridization assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003107 -->
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<obo:IAO_0000111>slide-seq assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An RNA-seq assay that involves transfer of RNA from tissue sections onto a surface covered in DNA-barcoded beads with known positions, allowing the locations of the RNA to be inferred by sequencing.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000119>url:https://science.sciencemag.org/content/363/6434/1463</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1414</obo:IAO_0000233>
<obo:IAO_0000234>CFDE</obo:IAO_0000234>
<rdfs:label>slide-seq assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003108 -->
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<obo:IAO_0000111>single-nucleus chromatin accessibility and mRNA expression sequencing assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A single-nucleus RNA sequencing assay that involves joint profiling of accessible chromatin and RNA within the same cells which enables direct matching of transcriptional regulation to its outputs.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>SNARE-seq</obo:IAO_0000118>
<obo:IAO_0000118>SNAREseq</obo:IAO_0000118>
<obo:IAO_0000119>url:https://www.nature.com/articles/s41587-019-0290-0</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1416</obo:IAO_0000233>
<obo:IAO_0000234>CFDE</obo:IAO_0000234>
<rdfs:label>single-nucleus chromatin accessibility and mRNA expression sequencing assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003109 -->
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<obo:IAO_0000111>single-nucleus RNA sequencing assay</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A RNA-seq assay that is used for profiling gene expression in individual nuclei with optimized next generation sequencing (NGS) technologies. This allows the RNA-seq profiling of cell types that are more vulnerable to the tissue dissociation process, and that are therefore underrepresented in the final data set in single cell sequencing.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>sNuc-seq</obo:IAO_0000118>
<obo:IAO_0000118>single nuclei RNA sequencing</obo:IAO_0000118>
<obo:IAO_0000118>snRNA-seq</obo:IAO_0000118>
<obo:IAO_0000119>EFO:0009809</obo:IAO_0000119>
<obo:IAO_0000119>url:https://www.biocompare.com/Editorial-Articles/557506-Advantages-of-Single-Nucleus-RNA-Sequencing/</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1415</obo:IAO_0000233>
<obo:IAO_0000234>CFDE</obo:IAO_0000234>
<rdfs:label>single-nucleus RNA sequencing assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003110 -->
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<obo:IAO_0000111>gas chromatography mass spectrometry assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A mass spectrometry assay combining mass spectrometry and gas chromatography for the qualitative as well as quantitative determination of compounds.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Rebecca Jackson</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>GC-MS</obo:IAO_0000118>
<obo:IAO_0000119>url:http://purl.bioontology.org/ontology/MESH/D008401</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1417</obo:IAO_0000233>
<obo:IAO_0000234>CFDE</obo:IAO_0000234>
<rdfs:label>gas chromatography mass spectrometry assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003111 -->
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<obo:IAO_0000111>SOMAscan assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that uses aptamers to detect protein analytes in serum.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
<obo:IAO_0000119>Rohloff JC, et al. Nucleic acid ligands with protein-like side chains: modified aptamers and their uses as diagnostic and therapeutic agents. Mol Ther Nucleic Acids. 2014;3:e201.</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1308</obo:IAO_0000233>
<obo:IAO_0000234>ImmPort</obo:IAO_0000234>
<rdfs:label>SOMAscan assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003112 -->
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<obo:IAO_0000115 xml:lang="en">A proximity extension assay that uses quantitative polymerase chain reaction (qPCR) technology to determine the concentration/presence of proteins using a high-multiplex, high-throughput protein biomarker platform. The assay utilizes two distinct oligonucleotide-labeled antibodies (‘probes’) that bind at different sites for each detected protein. When the two probes are in close proximity, a new PCR target sequence is formed by a proximity-dependent DNA polymerization event. The resulting sequence is subsequently detected and quantified using standard real-time PCR.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Hector Guzman-Orozco</obo:IAO_0000117>
<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
<obo:IAO_0000119>https://www.olink.com/</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1308</obo:IAO_0000233>
<obo:IAO_0000234>ImmPort</obo:IAO_0000234>
<rdfs:label>Olink assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003113 -->
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<obo:IAO_0000111>proximity extension assay</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">An analyte assay that uses quantitative polymerase chain reaction (qPCR) technology to determine the concentration/presence of an analyte or analyte complex.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Hector Guzman-Orozco</obo:IAO_0000117>
<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
<obo:IAO_0000119>Bjoern Peters</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1308</obo:IAO_0000233>
<obo:IAO_0000234>ImmPort</obo:IAO_0000234>
<rdfs:label>proximity extension assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003114 -->
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<obo:IAO_0000111>Illumina MiniSeq</obo:IAO_0000111>
<obo:IAO_0000112>Whole genome sequencing of Klebsiella pneumoniae ST11 was performed using an Illumina Miniseq Sequencing System. PMID:31493526</obo:IAO_0000112>
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<obo:IAO_0000115 xml:lang="en">A small benchtop DNA sequencer which is manufactured by the Illumina corporation with integrated cluster generation, sequencing and data analysis. The sequencer accommodates various flow cell configurations and can produce up to 25M single reads or 50M paired-end reads per run.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Bonita Lam</obo:IAO_0000117>
<obo:IAO_0000118>MiniSeq</obo:IAO_0000118>
<obo:IAO_0000119>url:https://www.illumina.com/systems/sequencing-platforms/miniseq.html</obo:IAO_0000119>
<rdfs:label>Illumina MiniSeq</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003115 -->
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<obo:IAO_0000111>antigen detection by cytometric bead array assay</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A cytometric bead array assay in which a series of beads are coated with antibodies specific to antigens of interest. Antigens of interest attach to antibodies on the beads. Fluorescent labeled secondary antibodies are used to detect the antigens of interest.</obo:IAO_0000115>
<obo:IAO_0000117>CMI-PB</obo:IAO_0000117>
<obo:IAO_0000119>CMI-PB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1399</obo:IAO_0000233>
<rdfs:label>antigen detection by cytometric bead array assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003116 -->
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<obo:IAO_0000115 xml:lang="en">A cytometric bead array assay that detects antigen-specific antibodies. In the assay a series of beads are coated with antigens which capture antibodies specific to the antigens. Fluorescent labeled secondary antibodies are used to detect the antibodies of interest.</obo:IAO_0000115>
<obo:IAO_0000117>CMI-PB</obo:IAO_0000117>
<obo:IAO_0000119>CMI-PB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1399</obo:IAO_0000233>
<rdfs:label>antibody detection by cytometric bead array assay</rdfs:label>
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<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that determines the 3-dimensional configuration of a molecular entity or molecular complex.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Hector Guzman-Orozco</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1380</obo:IAO_0000233>
<rdfs:label>3D molecular structure determination assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003118 -->
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<obo:IAO_0000111>electron-microscopy 3D molecular structure determination assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A 3D molecular structure determination assay that uses electron microscopy imaging.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Hector Guzman-Orozco</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1380</obo:IAO_0000233>
<rdfs:label>electron-microscopy 3D molecular structure determination assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003119 -->
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<obo:IAO_0000111>antigen:antibody complex</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A complex of molecular entitites which is the result of an antibody binding to an antigen.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Hector Guzman-Orozco</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>antigen:antibody complex</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003120 -->
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<obo:IAO_0000111>epitope:MHC:TCR complex</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A complex of molecular entities which is the result of a T cell receptor binding to a MHC-epitope complex.</obo:IAO_0000115>
<obo:IAO_0000117>Bjorne Peters</obo:IAO_0000117>
<obo:IAO_0000117>Hector Guzman-Orozco</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
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<!-- http://purl.obolibrary.org/obo/OBI_0003121 -->
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<obo:IAO_0000111>MHC:ligand complex</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A complex of molecular entities which is the result of a MHC molecule binding with a ligand.</obo:IAO_0000115>
<obo:IAO_0000117>Bjorne Peters</obo:IAO_0000117>
<obo:IAO_0000117>Hector Guzman-Orozco</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
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<!-- http://purl.obolibrary.org/obo/OBI_0003122 -->
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<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A 3D structure determination assay that determines the 3-dimensional configuration of a cell.</obo:IAO_0000115>
<obo:IAO_0000117>Hector Guzman-Orozco</obo:IAO_0000117>
<obo:IAO_0000117>Patrick Ray</obo:IAO_0000117>
<obo:IAO_0000119>Hector Guzman-Orozco</obo:IAO_0000119>
<obo:IAO_0000119>Patrick Ray</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1364</obo:IAO_0000233>
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<obo:IAO_0000111>3D neural cell structure determination assay</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A 3D cell structure determination assay that determines the 3-dimensional configuration of a neural cell.</obo:IAO_0000115>
<obo:IAO_0000117>Hector Guzman-Orozco</obo:IAO_0000117>
<obo:IAO_0000117>Patrick Ray</obo:IAO_0000117>
<obo:IAO_0000119>Hector Guzman-Orozco</obo:IAO_0000119>
<obo:IAO_0000119>Patrick Ray</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1364</obo:IAO_0000233>
<obo:IAO_0000234>Allen Institute for Brain Science</obo:IAO_0000234>
<rdfs:label>3D neural cell structure determination assay</rdfs:label>
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<obo:IAO_0000111>neuron morphology assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A 3D neural cell structure determination assay that determines the 3-dimensional configuration of a neuron.</obo:IAO_0000115>
<obo:IAO_0000117>Hector Guzman-Orozco</obo:IAO_0000117>
<obo:IAO_0000117>Patrick Ray</obo:IAO_0000117>
<obo:IAO_0000119>Patrick Ray</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1364</obo:IAO_0000233>
<obo:IAO_0000234>Allen Institute for Brain Science</obo:IAO_0000234>
<rdfs:label>neuron morphology assay</rdfs:label>
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<obo:IAO_0000111>mosaicism with repeat frameshift genetic sparse labeling</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A 3D neural cell structure determination assay where sparse and stochastic methods are used to label genetically-defined neurons.</obo:IAO_0000115>
<obo:IAO_0000117>Patrick Ray</obo:IAO_0000117>
<obo:IAO_0000118>MORF genetic sparse labeling</obo:IAO_0000118>
<obo:IAO_0000119>https://biccn.org/teams/u01-yang</obo:IAO_0000119>
<obo:IAO_0000119>https://doi.org/10.1016/j.neuron.2020.07.019</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1364</obo:IAO_0000233>
<obo:IAO_0000234>Allen Institute for Brain Science</obo:IAO_0000234>
<rdfs:label>mosaicism with repeat frameshift genetic sparse labeling</rdfs:label>
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<obo:IAO_0000111>neuron morphology reconstruction assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A neuron morphology assay where the morphology or structure of a neuron is represented. Often, this assay is a combination of different assays (sparse labelling, fluorescent labeling, fMOST).</obo:IAO_0000115>
<obo:IAO_0000116>The representation of the morphology (3D structure) of a neuron can be a summary of various measurements relating to the dimensions of the neuron in question.</obo:IAO_0000116>
<obo:IAO_0000117>Hector Guzman-Orozco</obo:IAO_0000117>
<obo:IAO_0000117>Patrick Ray</obo:IAO_0000117>
<obo:IAO_0000119>http://doi.org/10.1101/675280</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1364</obo:IAO_0000233>
<obo:IAO_0000234>Allen Institute for Brain Science</obo:IAO_0000234>
<rdfs:label>neuron morphology reconstruction assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003127 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110128"/>
<obo:IAO_0000111>B cell epitope assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An immune epitope assay that characterizes the structrue of an antibody-epitope complex, or measures the binding of an antibody receptor to epitope, or the immune response process resulting from such a binding event or the recognition of the epitope.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>B cell assay|any method</obo:OBI_9991118>
<rdfs:label>B cell epitope assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003128 -->
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<obo:IAO_0000111>T cell epitope assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An immune epitope assay that characterizes the structrue of an epitope-T cell receptor complex, or measures the binding of a T cell receptor to epitope, or the immune response process resulting from such a binding event or the recognition of the epitope.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>T cell assay|any method</obo:OBI_9991118>
<rdfs:label>T cell epitope assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003129 -->
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<obo:IAO_0000111>chemical mutagenesis</obo:IAO_0000111>
<obo:IAO_0000112>129/Sv male mice were injected with ENU and mated to C57BL/6 females. Their first-generation (G1) male progeny were again crossed to C57BL/6 females, and then backcrossed to one of their second-generation (G2) daughters to yield a third-generation (G3). PMID:18802465</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A form of random mutagenesis that produces a mutation by introducing the organism to a chemical mutagen.</obo:IAO_0000115>
<obo:IAO_0000116>Equivalent to FlyBase "chemical" (FBcv:0000525) in the origin of mutation branch and Dd mutagenesis meth0d term chemical mutagenesis (DDMUMET:0000014).</obo:IAO_0000116>
<obo:IAO_0000117>Susan Bello ORCID:orcid.org/0000-0003-4606-0597</obo:IAO_0000117>
<obo:IAO_0000119>url:https://pubmed.ncbi.nlm.nih.gov/25646611/</obo:IAO_0000119>
<rdfs:label>chemical mutagenesis</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003130 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002620"/>
<obo:IAO_0000111>irradiation mutagenesis</obo:IAO_0000111>
<obo:IAO_0000112>Groups of (101 x C3H)F1 hybrid male mice 11 weeks old were exposed to two different doses of 137Cs gamma rays. PMID:7035547</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A form of random mutagenesis that produces a random mutation by exposing the organism to radiation.</obo:IAO_0000115>
<obo:IAO_0000116>Equivalent to FlyBase "irradiation" (FBcv:0000503) in the origin of mutation branch.</obo:IAO_0000116>
<obo:IAO_0000117>Susan Bello ORCID:orcid.org/0000-0003-4606-0597</obo:IAO_0000117>
<obo:IAO_0000118>radiation induced mutagenesis</obo:IAO_0000118>
<obo:IAO_0000119>url:http://purl.obolibrary.org/obo/FBcv_0000503</obo:IAO_0000119>
<rdfs:label>irradiation mutagenesis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003131 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003131">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001154"/>
<obo:IAO_0000111>directed mutagenesis</obo:IAO_0000111>
<obo:IAO_0000112>Exons 20 and 21 were targeted for deletion because they encode the signature and Walker B motifs of the first ATP-binding domain, elements that are known to be critical for ABCA1 function. PMID:15550377</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An induced mutation in which a specific gene(s) or part of a gene(s) is altered.</obo:IAO_0000115>
<obo:IAO_0000117>Susan Bello ORCID:orcid.org/0000-0003-4606-0597</obo:IAO_0000117>
<obo:IAO_0000119>url:https://www.ncbi.nlm.nih.gov/books/NBK21878/def-item/A4754/</obo:IAO_0000119>
<rdfs:label>directed mutagenesis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003132 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003132">
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<obo:IAO_0000111>endonuclease mediated mutagenesis</obo:IAO_0000111>
<obo:IAO_0000112>We have generated a WMS mouse model with S236X mutation in ADAMTS10 which is similar to the R237X mutation identifiedin WMS patients using CRISPR-Cas9. PMID:30060141</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A directed mutagenesis in which guide RNAs and an endonuclease (cas9, TALEN) are used to introduce a mutation at a specific location in a gene.</obo:IAO_0000115>
<obo:IAO_0000116>Equivalent to FlyBase term "site specific cleavage" (FBcv:0003007) in the origin of mutation branch.</obo:IAO_0000116>
<obo:IAO_0000117>Susan Bello ORCID:orcid.org/0000-0003-4606-0597</obo:IAO_0000117>
<obo:IAO_0000119>url:https://pubmed.ncbi.nlm.nih.gov/28177771/</obo:IAO_0000119>
<rdfs:label>endonuclease mediated mutagenesis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003133 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003133">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003132"/>
<obo:IAO_0000111>cas mediated mutagenesis</obo:IAO_0000111>
<obo:IAO_0000112>Briefly, to create Adar1 M249A/M249A mice, guide RNA targeting 5’-ACCTTCTGAGCCTCTTGACA-3’ was synthesized by using Gene Art Precisiong RNA Synthesis Kit (ThermoFisherScientific). Pronuclear-stage mouse embryos (CLEA Japan Inc., Tokyo, Japan) were electroporated to introduce Cas9 mRNA, the guide RNA and a single-stranded donor... PMID:33983932</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An endonuclease mediated mutagenesis in which guide RNAs and cas are used to introduce a mutation at a specific location in the genome.</obo:IAO_0000115>
<obo:IAO_0000116>Equivalent (narrow match) to FlyBase term "CRISPR/Cas9" (FBcv:0003008, narrow match as the OBI term covers all forms of cas) in the origin of mutation branch and Dd mutagenesis method term "CRISPR/Cas9" (DDMUMET:0000025).</obo:IAO_0000116>
<obo:IAO_0000117>Susan Bello ORCID:orcid.org/0000-0003-4606-0597</obo:IAO_0000117>
<obo:IAO_0000118>CRISPR mediated mutagenesis</obo:IAO_0000118>
<obo:IAO_0000118>CRISPR/cas mediated mutagenesis</obo:IAO_0000118>
<obo:IAO_0000119>url:https://pubmed.ncbi.nlm.nih.gov/28177771/</obo:IAO_0000119>
<rdfs:label>cas mediated mutagenesis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003134 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003134">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003132"/>
<obo:IAO_0000111>TALEN mediated mutagenesis</obo:IAO_0000111>
<obo:IAO_0000112>We designed transcription activator-like effector nucleases (TALENs) and a single-stranded oligo (ssOligo) donor template to edit the endogenous Actb locus within the mouse genome. PMID:30012594</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An endonuclease mediated mutagenesis in which guide RNAs and transcription activator-like effector nucleases (TALENs) are used to introduce a mutation at a specific location in the genome.</obo:IAO_0000115>
<obo:IAO_0000116>Equivalent to FlyBase term "TALEN" (FBcv:0003009) in the origin of mutation branch.</obo:IAO_0000116>
<obo:IAO_0000117>Susan Bello ORCID:orcid.org/0000-0003-4606-0597</obo:IAO_0000117>
<obo:IAO_0000119>url:https://pubmed.ncbi.nlm.nih.gov/23664777/</obo:IAO_0000119>
<rdfs:label>TALEN mediated mutagenesis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003135 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003135">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003132"/>
<obo:IAO_0000111>zinc finger mediated mutagenesis</obo:IAO_0000111>
<obo:IAO_0000112>ZFN constructs targeting the third exon of the mouse Apoc2 gene were designed and synthetized by Sigma Aldrich... PMID:26574515</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An endonuclease mediated mutagenesis in which synthetic zinc-finger proteins designed to target specific DNA sequences are used to introduce a mutation at a specific location in the genome.</obo:IAO_0000115>
<obo:IAO_0000116>Equivalent to FlyBase term "ZFN" (FBcv:0003239) in the origin of mutation branch.</obo:IAO_0000116>
<obo:IAO_0000117>Susan Bello ORCID:orcid.org/0000-0003-4606-0597</obo:IAO_0000117>
<obo:IAO_0000118>ZFN mediated mutagenesis</obo:IAO_0000118>
<obo:IAO_0000119>url:https://pubmed.ncbi.nlm.nih.gov/23664777/</obo:IAO_0000119>
<rdfs:label>zinc finger mediated mutagenesis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003136 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003136">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002620"/>
<obo:IAO_0000111>transgenic mutagenesis</obo:IAO_0000111>
<obo:IAO_0000112>Transgenic mice were then generated by pronuclear injection of either the mixed MoPrP-PS1 and MoPrP-APP or the bicistronic MoPrP–APP/IRES/PS1 expression cassettes into single cell embryos derived from F2 hybrids of C57BL/6J and C3H/HeJ mice... PMID:11337275</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A form of random mutagenesis that produces a mutation by introducing a construct into the genome of an organism in a random or semi-random fashion.</obo:IAO_0000115>
<obo:IAO_0000117>Susan Bello ORCID:orcid.org/0000-0003-4606-0597</obo:IAO_0000117>
<obo:IAO_0000119>url:https://pubmed.ncbi.nlm.nih.gov/23996268/</obo:IAO_0000119>
<rdfs:label>transgenic mutagenesis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003137 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003137">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003136"/>
<obo:IAO_0000111>gene-trap mutagenesis</obo:IAO_0000111>
<obo:IAO_0000112>Constructs lacking a promoter and including a B3-galactosidase gene, or a reporter gene encoding a protein with both B3-galactosidase and neomycin phosphotransferase activity, were designed so that activation of the reporter gene depends on its insertion within an active transcription unit. PMID:1653172</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A transgenic mutagenesis that produces a mutation by introducing a construct designed to capture the expression of an endogenous gene by creating a spliced fusion transcript when inserted into the genome of an organism.</obo:IAO_0000115>
<obo:IAO_0000117>Susan Bello ORCID:orcid.org/0000-0003-4606-0597</obo:IAO_0000117>
<obo:IAO_0000119>url:https://pubmed.ncbi.nlm.nih.gov/17877761/</obo:IAO_0000119>
<rdfs:label>gene-trap mutagenesis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003138 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003138">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003136"/>
<obo:IAO_0000111>enhancer-trap mutagenesis</obo:IAO_0000111>
<obo:IAO_0000112>We generated several lines of enhancer trap mice carrying an enhancer detector cassette expressing Cre recombinase under the transcriptional control of the minimal promoter (129 base pairs) of the mouse Thy-1.2 gene. PMID:22492032</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A transgenic mutagenesis that produces a mutation by introducing a construct designed to monitor transcriptionally active regions when inserted into the genome of an organism by inserting a reporter gene that requires cis-acting DNA sequences in the genome to activate reporter gene expression.</obo:IAO_0000115>
<obo:IAO_0000117>Susan Bello ORCID:orcid.org/0000-0003-4606-0597</obo:IAO_0000117>
<obo:IAO_0000119>url:https://pubmed.ncbi.nlm.nih.gov/17877761/</obo:IAO_0000119>
<rdfs:label>enhancer-trap mutagenesis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003139 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003139">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003131"/>
<obo:IAO_0000111>targeted mutagenesis</obo:IAO_0000111>
<obo:IAO_0000112>To disrupt the mdr1a gene a 1.6 kb NheI genomic fragment containing exons 6 and 7 was replaced by a hygromycin phosphotransferase cassette in a targeting vector. PMID:7910522</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A directed mutation in which a construct is used to introduce a mutation into a specific genome location through homologous recombination.</obo:IAO_0000115>
<obo:IAO_0000116>Equivalent to FlyBase term "gene targeting by homologous recombination" (FBcv:0000710) in the origin of mutation branch.</obo:IAO_0000116>
<obo:IAO_0000117>Susan Bello ORCID:orcid.org/0000-0003-4606-0597</obo:IAO_0000117>
<obo:IAO_0000118>gene targeting by homologous recombination</obo:IAO_0000118>
<obo:IAO_0000119>url:https://pubmed.ncbi.nlm.nih.gov/23996268/</obo:IAO_0000119>
<rdfs:label>targeted mutagenesis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003140 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003140">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002620"/>
<obo:IAO_0000111>transposon-induced mutagenesis</obo:IAO_0000111>
<obo:IAO_0000112>In order to achieve SB transposon-mediated mutagenesis in mice, we employed the gene trap scheme using a novel transposon vector, and we have generated a large number of mutant mice, approximately 30% of which displayed the phenotype. PMID:16880528</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A random mutagenesis in which expression of a transposase causes the mobilization of an artificial or modified transposable element with the insertion of the element into the genome creating a mutation.</obo:IAO_0000115>
<obo:IAO_0000116>Equivalent to FlyBase "transposable element activity" (FBcv:0000483) in the origin of mutation branch.</obo:IAO_0000116>
<obo:IAO_0000117>Susan Bello ORCID:orcid.org/0000-0003-4606-0597</obo:IAO_0000117>
<obo:IAO_0000119>url:https://pubmed.ncbi.nlm.nih.gov/32050713/</obo:IAO_0000119>
<rdfs:label>transposon-induced mutagenesis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003141 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003141">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001181"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0001938"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001930"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>categorical binding datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A binding datum that is expressed as a categorical value.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000118>qualitative binding datum</obo:IAO_0000118>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>categorical binding datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003142 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003142">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001181"/>
<obo:IAO_0000111>quantitative binding datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A binding datum that is expressed using numbers.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>quantitative binding datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003143 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003143">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003142"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001180"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001588"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001180"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003142"/>
<obo:IAO_0000111>EC50 binding datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A quantitative binding datum that is expressed as a half-maximal effective concentration (EC50).</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Hector Guzman-Orozco</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>EC50 binding datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003144 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003144">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003142"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001191"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001588"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001191"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003142"/>
<obo:IAO_0000111>IC50 binding datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A quantitative binding datum that is expressed as a half-maximal inhibitory concentration (IC50).</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Hector Guzman-Orozco</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>IC50 binding datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003145 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003145">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0003142"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001503"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110126"/>
<obo:IAO_0000111>assay measuring quantitative binding of a MHC:ligand complex</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that detects the binding of a MHC molecule with a ligand, and produces a quantitative measurement of the binding as an output.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>quantitative binding|binding assay</obo:OBI_9991118>
<rdfs:label>assay measuring quantitative binding of a MHC:ligand complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003146 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003146">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0003142"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001702"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110127"/>
<obo:IAO_0000111>assay measuring quantitative binding of an antigen:antibody complex</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that detects the binding of an antigen with an antibody, and produces a quantitative measurement of the binding as an output.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>quantitative binding|binding assay</obo:OBI_9991118>
<rdfs:label>assay measuring quantitative binding of an antigen:antibody complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003147 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003147">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0003142"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110037"/>
<obo:IAO_0000111>assay measuring quantitative binding of an epitope:MHC:TCR complex</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that detects the binding of a MHC:epitope complex with a T cell receptor, and produces a quantitative measurement of the binding as an output.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>quantitative binding|binding assay</obo:OBI_9991118>
<rdfs:label>assay measuring quantitative binding of an epitope:MHC:TCR complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003148 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003148">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100022"/>
<obo:IAO_0000111>albumin concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An albumin assay that measures the concentration of albumin in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>albumin concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003149 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003149">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003021"/>
<obo:IAO_0000111>basophil percentage assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A basophil assay that measures the percentage of basophils in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>basophil percentage assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003150 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003150">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100024"/>
<obo:IAO_0000111>calcium cation concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A calcium cation assay that measures the concentration of calcium cations in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>calcium cation concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003151 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003151">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100010"/>
<obo:IAO_0000111>chloride concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A chloride assay that measures the concentration of chloride in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>chloride concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003152 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003152">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100031"/>
<obo:IAO_0000111>cholesterol concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A cholesterol assay that measures the concentration of cholesterol in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>cholesterol concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003153 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003153">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100003"/>
<obo:IAO_0000111>creatinine concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A creatinine assay that measures the concentration of creatinine in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>creatinine concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003154 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003154">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003023"/>
<obo:IAO_0000111>eosinophil percentage assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An eosinophil assay that measures the percentage of eosinophils in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>eosinophil percentage assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003155 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003155">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003015"/>
<obo:IAO_0000111>globulin concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A globulin assay that measures the concentration of globulin in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>globulin concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003156 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003156">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100014"/>
<obo:IAO_0000111>hemoglobin concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A hemoglobin assay that measures the amount of hemoglobin in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>hemoglobin concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003157 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003157">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100030"/>
<obo:IAO_0000111>high-density lipoprotein cholesterol concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A high-density lipoprotein cholesterol assay that measures the concentration of high-density lipoprotein cholesterol in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>high-density lipoprotein cholesterol concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003158 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003158">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003011"/>
<obo:IAO_0000111>iron concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An iron assay that measures the concentration of iron cation in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>iron concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003159 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003159">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100032"/>
<obo:IAO_0000111>low-density lipoprotein cholesterol concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A low-density lipoprotein cholesterol assay that measures the concentration of low-density lipoprotein cholesterol in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>low-density lipoprotein cholesterol concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003160 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003160">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003024"/>
<obo:IAO_0000111>lymphocyte percentage assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A lymphocyte assay that measures the percentage of lymphocytes in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>lymphocyte percentage assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003161 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003161">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003017"/>
<obo:IAO_0000111>metamyelocyte count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A metamyelocyte assay that measures the number of metamyelocytes in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>metamyelocyte count assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003162 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003162">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003017"/>
<obo:IAO_0000111>metamyelocyte percentage assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A metamyelocyte assay that measures the percentage of metamyelocytes in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>metamyelocyte percentage assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003163 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003163">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100040"/>
<obo:IAO_0000111>methemoglobin percentage assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A methemoglobin assay that measures the percentage of methemoglobin in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>methemoglobin percentage assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003164 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003164">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003025"/>
<obo:IAO_0000111>monocyte percentage assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A monocyte assay that measures the percentage of monocytes in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>monocyte percentage assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003165 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003165">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003016"/>
<obo:IAO_0000111>myelocyte count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A myelocyte assay that measures the number of myelocytes in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>myelocyte count assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003166 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003166">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003022"/>
<obo:IAO_0000111>neutrophil percentage assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A neutrophil assay that measures the percentage of neutrophils in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>neutrophil percentage assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003167 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003167">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100015"/>
<obo:IAO_0000111>phosphate ion concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A phosphate ion assay that measures the concentration of phosphate ions in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>phosphate ion concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003168 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003168">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100004"/>
<obo:IAO_0000111>potassium(1+) concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A potassium(1+) assay that measures the concentration of potassium(1+) in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>potassium(1+) concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003170 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003170">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003026"/>
<obo:IAO_0000111>reticulocyte percentage assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A reticulocyte assay that measures the percentage of reticulocytes in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>reticulocyte percentage assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003171 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003171">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100002"/>
<obo:IAO_0000111>sodium(1+) concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A sodium(1+) assay that measures the concentration of sodium(1+) in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>sodium(1+) concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003172 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003172">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100033"/>
<obo:IAO_0000111>thyroid stimulating hormone concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A thyroid stimulating hormone assay that measures the concentration of thyroid stimulating hormone in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>thyroid stimulating hormone concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003173 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003173">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100029"/>
<obo:IAO_0000111>triglyceride concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A triglyceride assay that measures the concentration of triglycerides in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>triglyceride concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003174 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003174">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100046"/>
<obo:IAO_0000111>3,3',5'-triiodothyronine concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A 3,3',5'-triiodothyronine assay that measures the concentration of 3,3',5'-triiodothyronine in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>3,3',5'-triiodothyronine concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003175 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003175">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003010"/>
<obo:IAO_0000111>fibrinogen concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A fibrinogen assay that measures the concentration of fibrinogen in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>fibrinogen concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003176 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003176">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100035"/>
<obo:IAO_0000111>free thyroxine concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A thyroxine assay that measures the concentration of free thyroxine in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>free thyroxine concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003177 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003177">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100035"/>
<obo:IAO_0000111>total thyroxine concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A thyroxine assay that measures the concentration of total thyroxine in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>total thyroxine concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003180 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003180">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100018"/>
<obo:IAO_0000111>direct bilirubin concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A bilirubin IXalpha assay that measures the concentration of direct bilirubin in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>direct bilirubin concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003181 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003181">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100018"/>
<obo:IAO_0000111>indirect bilirubin concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A bilirubin IXalpha assay that measures the concentration of indirect bilirubin in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>indirect bilirubin concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003182 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003182">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100018"/>
<obo:IAO_0000111>total bilirubin concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A bilirubin IXalpha assay that measures the concentration of total bilirubin in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>total bilirubin concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003183 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003183">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100014"/>
<obo:IAO_0000111>mean cell hemoglobin assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A hemoglobin assay that measures the average concentration of hemoglobin in a population of erythrocytes.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>mean cell hemoglobin assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003184 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003184">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100014"/>
<obo:IAO_0000111>mean cell hemoglobin concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A hemoglobin assay that measures the concentration of hemoglobin in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>mean cell hemoglobin concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003185 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003185">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003028"/>
<obo:IAO_0000111>mean platelet volume assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A platelet assay that measures the average volume of platelets in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>mean platelet volume assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003186 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003186">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003022"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002444"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000776"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000776"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000776"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>immature neutrophil count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A neutrophil assay that measures the number of immature neutrophils in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>immature neutrophil count assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003187 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003187">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003022"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002444"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000776"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000776"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000776"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>immature neutrophil percentage assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An neutrophil assay that measures the percentage of immature neutrophils in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>immature neutrophil percentage assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003188 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003188">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003190"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002444"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000562"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000562"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000562"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>nucleated erythrocyte percentage assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An erythrocyte assay that measures the percentage of nucleated erythrocytes in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>nucleated erythrocyte percentage assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003189 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003189">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003190"/>
<obo:IAO_0000111>mean cell volume assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An erythrocyte assay that measures the average volume of erythrocytes in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>mean cell volume assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003190 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003190">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003018"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002444"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000232"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000232"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000232"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>erythrocyte assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the abundance and/or characteristics of erythrocytes.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>erythrocyte assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003191 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003191">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003018"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002444"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000232"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000232"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000232"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>manual hematocrit assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A hematocrit assay that measures the percentage of erythrocytes in a specimen by manual processes.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>manual hematocrit assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003192 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003192">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100023"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000003777"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000003777"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>adiponectin assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of adiponectin</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>adiponectin assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003193 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003193">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003192"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000003777"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000003777"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>adiponectin concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An adiponectin assay that measures the concentration of adiponectin in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>adiponectin concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003194 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003194">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16919"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16919"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>creatine assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of creatine</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>creatine assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003195 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003195">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003194"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16919"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16919"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>creatine concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A creatine assay that measures the concentration of creatine in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>creatine concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003196 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003196">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23965"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23965"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>estradiol assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of estradiol</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>estradiol assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003197 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003197">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003196"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23965"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23965"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>estradiol concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An estradiol assay that measures the concentration of estradiol in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>estradiol concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003202 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003202">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100023"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000009758"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000009758"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>leptin assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of leptin</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>leptin assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003203 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003203">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003202"/>
<obo:IAO_0000111>leptin concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An leptin assay that measures the concentration of leptin in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>leptin concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003204 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003204">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_6495"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_6495"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>lipoprotein concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of lipoprotein</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>lipoprotein concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003205 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003205">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003204"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_39025"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_39025"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>high-density lipoprotein concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A lipoprotein concentration assay that measures the concentration of high-density lipoprotein in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>high-density lipoprotein concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003206 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003206">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003204"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_39026"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_39026"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>low-density lipoprotein concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A lipoprotein concentration assay that measures the concentration of low-density lipoprotein in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>low-density lipoprotein concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003207 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003207">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003204"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_39027"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_39027"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>very-low-density lipoprotein concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A lipoprotein concentration assay that measures the concentration of very-low-density lipoprotein in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>very-low-density lipoprotein concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003208 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003208">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_81568"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_81568"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>luteinizing hormone assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of luteinizing hormone</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>luteinizing hormone assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003209 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003209">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003208"/>
<obo:IAO_0000111>luteinizing hormone concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A luteinizing hormone assay that measures the concentration of luteinizing hormone in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>luteinizing hormone concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003210 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003210">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16301"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16301"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>nitrite assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of nitrite</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>nitrite assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003211 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003211">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003210"/>
<obo:IAO_0000111>nitrite concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A nitrite assay that measures the concentration of nitrite in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>nitrite concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003212 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003212">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16247"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16247"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>phospholipid assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of phospholipid</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>phospholipid assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003213 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003213">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003212"/>
<obo:IAO_0000111>phospholipid concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A phospholipid assay that measures the concentration of phospholipids in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>phospholipid concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003214 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003214">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17026"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17026"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>progesterone assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of progesterone</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>progesterone assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003215 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003215">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003214"/>
<obo:IAO_0000111>progesterone concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A progesterone assay that measures the concentration of progesterone in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>progesterone concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003216 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003216">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17347"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17347"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>testosterone assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of testosterone</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>testosterone assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003217 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003217">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003216"/>
<obo:IAO_0000111>testosterone concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A testosterone assay that measures the concentration of testosterone in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>testosterone concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003218 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003218">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_22868"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_22868"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>bile salt assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of bile salt</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>bile salt assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003219 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003219">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003218"/>
<obo:IAO_0000111>bile salt concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A bile salt assay that measures the concentration of bile salt in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>bile salt concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003220 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003220">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35366"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35366"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>fatty acid assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of fatty acid</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>fatty acid assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003221 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003221">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003220"/>
<obo:IAO_0000111>free fatty acid concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A fatty acid assay that measures the concentration of free fatty acids in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>free fatty acid concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003222 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003222">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_145810"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_145810"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>insulin assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of insulin</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>insulin assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003223 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003223">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003222"/>
<obo:IAO_0000111>insulin concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A insulin assay that measures the concentration of insulin in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>insulin concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003224 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003224">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_81569"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_81569"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>follicle stimulating hormone assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of follicle stimulating hormone</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>follicle stimulating hormone assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003225 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003225">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003224"/>
<obo:IAO_0000111>follicle stimulating hormone concentration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A follicle stimulating hormone assay that measures the concentration of follicle stimulating hormone in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>follicle stimulating hormone concentration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003226 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003226">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003024"/>
<obo:IAO_0000111>total lymphocyte count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A lymphocyte assay that measures the number of lymphocytes and large unstained cells in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>total lymphocyte count assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003227 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003227">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003024"/>
<obo:IAO_0000111>total lymphocyte percentage assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A lymphocyte assay that measures the percentage of lymphocytes and large unstained cells in a specimen.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>total lymphocyte percentage assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003228 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003228">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001977"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001501"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003368"/>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>fluorescent immunospot assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that detects the presence of cells that secrete a material of interest (analyte). In the assay, a plate is coated with an antibody specific to the analyte of interest. These antibodies capture the analytes secreted by the cells. The analytes are then detected using fluorescent labeled secondary antibodies.</obo:IAO_0000115>
<obo:IAO_0000117>Hector Guzman-Orozco</obo:IAO_0000117>
<obo:IAO_0000118>FLUOROSPOT</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/ELISpot#Mechanism_of_FluoroSpot</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1414</obo:IAO_0000233>
<obo:IAO_0000234>CMI-PB</obo:IAO_0000234>
<rdfs:label>fluorescent immunospot assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003229 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003229">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001318"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100016"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>plasma proteomics assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A proteomics profiling assay that detects proteins in a blood plasma specimen.</obo:IAO_0000115>
<obo:IAO_0000117>Hector Guzman-Orozco</obo:IAO_0000117>
<obo:IAO_0000119>CMI-PB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1414</obo:IAO_0000233>
<obo:IAO_0000234>CMI-PB</obo:IAO_0000234>
<rdfs:label>plasma proteomics assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003230 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003230">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000916"/>
<obo:IAO_0000111>T cell activation induced marker assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A flow cytometry assay that detects the presence/amount of antigen-specific T cells without the need to identify their cytokine production. Instead, antigen-specific T cells are detected on the basis of upregulation of TCR stimulation-induced surface markers.</obo:IAO_0000115>
<obo:IAO_0000117>Hector Guzman-Orozco</obo:IAO_0000117>
<obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955771/</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1414</obo:IAO_0000233>
<obo:IAO_0000234>CMI-PB</obo:IAO_0000234>
<rdfs:label>T cell activation induced marker assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003231 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003231">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110095"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000655"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>leukapheresis</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A blood harvesting process in which white blood cells are separated from a blood specimen.</obo:IAO_0000115>
<obo:IAO_0000117>Hector Guzman-Orozco</obo:IAO_0000117>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Leukapheresis</obo:IAO_0000119>
<rdfs:label>leukapheresis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003232 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003232">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002502"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002502"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>cerebrospinal fluid assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that has a cerebrospinal fluid specimen as evaluant.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1429</obo:IAO_0000233>
<rdfs:label>cerebrospinal fluid assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003233 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003233">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002972"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002972"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>endotracheal aspirate assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that has an endotracheal aspirate specimen as evaluant.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1429</obo:IAO_0000233>
<rdfs:label>endotracheal aspirate assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003234 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003234">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002746"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002746"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>induced sputum assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that has an induced sputum specimen as evaluant.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1429</obo:IAO_0000233>
<rdfs:label>induced sputum assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003235 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003235">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002534"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002534"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>lung assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that has a lung specimen as evaluant.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1429</obo:IAO_0000233>
<rdfs:label>lung assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003236 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003236">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002505"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002505"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>milk assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that has a milk specimen as evaluant.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1429</obo:IAO_0000233>
<rdfs:label>milk assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003237 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003237">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002503"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002503"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>feces assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that has a feces specimen as evaluant.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1429</obo:IAO_0000233>
<rdfs:label>feces assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003238 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003238">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000012"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_2000012"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<obo:IAO_0000111>umbilical cord blood assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that has an umbilical cord blood specimen as evaluant.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1429</obo:IAO_0000233>
<rdfs:label>umbilical cord blood assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003239 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003239">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002507"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002507"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>saliva assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that has a saliva specimen as evaluant.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1429</obo:IAO_0000233>
<rdfs:label>saliva assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003240 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003240">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003232"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003498"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002502"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002502"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>cerebrospinal fluid microbiology assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An organism detection assay that detects microorganisms in a cerebrospinal fluid specimen.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1429</obo:IAO_0000233>
<rdfs:label>cerebrospinal fluid microbiology assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003241 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003241">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003233"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003498"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002972"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002972"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
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<obo:IAO_0000115 xml:lang="en">An organism detection assay that detects microorganisms in an endotracheal aspirate specimen.</obo:IAO_0000115>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1429</obo:IAO_0000233>
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<obo:IAO_0000115 xml:lang="en">A data item that is the specified output of a blood assay.</obo:IAO_0000115>
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<rdfs:label>blood assay datum</rdfs:label>
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<obo:IAO_0000115 xml:lang="en">An organism detection datum that is the specified output of a blood microbiology assay.</obo:IAO_0000115>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1428</obo:IAO_0000233>
<rdfs:label>blood microbiology datum</rdfs:label>
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<obo:IAO_0000115 xml:lang="en">A data item that is the specified output of a feces assay.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1428</obo:IAO_0000233>
<rdfs:label>feces assay datum</rdfs:label>
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<obo:IAO_0000115 xml:lang="en">An organism detection datum that is the specified output of a feces microbiology assay.</obo:IAO_0000115>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1428</obo:IAO_0000233>
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<obo:IAO_0000115 xml:lang="en">A data item that is the specified output of a urine assay.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1428</obo:IAO_0000233>
<rdfs:label>urine assay datum</rdfs:label>
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<obo:IAO_0000115 xml:lang="en">An organism detection datum that is the specified output of a urine microbiology assay.</obo:IAO_0000115>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1428</obo:IAO_0000233>
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<obo:IAO_0000115 xml:lang="en">An organization that performs assays, processes specimens, analyses data and conducts planned processes relevant to the life sciences.</obo:IAO_0000115>
<obo:IAO_0000117>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000117>Jie Zheng ORCID:0000-0002-2999-0103</obo:IAO_0000117>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1436</obo:IAO_0000233>
<obo:IAO_0000234>OBIB</obo:IAO_0000234>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1428</obo:IAO_0000233>
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<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1428</obo:IAO_0000233>
<rdfs:label>cerebrospinal fluid assay datum</rdfs:label>
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<obo:IAO_0000115 xml:lang="en">An organism detection datum that is the specified output of a cerebrospinal fluid microbiology assay.</obo:IAO_0000115>
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<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1428</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1428</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1428</obo:IAO_0000233>
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<obo:IAO_0000115 xml:lang="en">An organism detection datum that is the specified output of a lung microbiology assay.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1428</obo:IAO_0000233>
<rdfs:label>lung microbiology datum</rdfs:label>
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<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1428</obo:IAO_0000233>
<rdfs:label>nasopharyngeal or oropharyngeal swab microbiology datum</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003258 -->
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<obo:IAO_0000115 xml:lang="en">An organism detection datum that is the specified output of a pleural fluid microbiology assay.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1428</obo:IAO_0000233>
<rdfs:label>pleural fluid microbiology datum</rdfs:label>
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<obo:IAO_0000111>umbilical cord blood assay datum</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A data item that is the specified output of an umbilical cord blood assay.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1428</obo:IAO_0000233>
<rdfs:label>umbilical cord blood assay datum</rdfs:label>
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<obo:IAO_0000111>umbilical cord blood microbiology datum</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">An organism detection datum that is the specified output of an umbilical cord blood microbiology assay.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1428</obo:IAO_0000233>
<rdfs:label>umbilical cord blood microbiology datum</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003261 -->
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<obo:IAO_0000111>bacteria in blood datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A blood microbiology datum that is about bacteria.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1428</obo:IAO_0000233>
<rdfs:label>bacteria in blood datum</rdfs:label>
</owl:Class>
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<obo:IAO_0000111>virus in blood datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A blood microbiology datum that is about a virus.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1428</obo:IAO_0000233>
<rdfs:label>virus in blood datum</rdfs:label>
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<obo:IAO_0000111>eukaryota in blood datum</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A blood microbiology datum that is about eukaryota.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1428</obo:IAO_0000233>
<rdfs:label>eukaryota in blood datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003264 -->
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<obo:IAO_0000111>bacteria in feces datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A feces microbiology datum that is about bacteria.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1428</obo:IAO_0000233>
<rdfs:label>bacteria in feces datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003265 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003265">
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<obo:IAO_0000111>eukaryota in feces datum</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A feces microbiology datum that is about eukaryota.</obo:IAO_0000115>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1428</obo:IAO_0000233>
<rdfs:label>eukaryota in feces datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003266 -->
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<obo:IAO_0000111>virus in feces datum</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A feces microbiology datum that is about a virus.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1428</obo:IAO_0000233>
<rdfs:label>virus in feces datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003267 -->
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<obo:IAO_0000111>eukaryota in urine datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A urine microbiology datum that is about eukaryota.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1428</obo:IAO_0000233>
<rdfs:label>eukaryota in urine datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003268 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003268">
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<obo:IAO_0000115 xml:lang="en">An induced sputum microbiology datum that is about bacteria.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1428</obo:IAO_0000233>
<rdfs:label>bacteria in induced sputum datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003269 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003269">
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<obo:IAO_0000115 xml:lang="en">An induced sputum microbiology datum that is about eukaryota.</obo:IAO_0000115>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1428</obo:IAO_0000233>
<rdfs:label>eukaryota in induced sputum datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003270 -->
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<obo:IAO_0000111>virus in induced sputum datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An induced sputum microbiology datum that is about a virus.</obo:IAO_0000115>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1428</obo:IAO_0000233>
<rdfs:label>virus in induced sputum datum</rdfs:label>
</owl:Class>
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<obo:IAO_0000111>bacteria in endotracheal tube aspirate datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An endotracheal tube aspirate microbiology datum that is about bacteria.</obo:IAO_0000115>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1428</obo:IAO_0000233>
<rdfs:label>bacteria in endotracheal tube aspirate datum</rdfs:label>
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<obo:IAO_0000115 xml:lang="en">A lung microbiology datum that is about bacteria.</obo:IAO_0000115>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1428</obo:IAO_0000233>
<rdfs:label>bacteria in lung datum</rdfs:label>
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<obo:IAO_0000115 xml:lang="en">A lung microbiology datum that is about eukaryota.</obo:IAO_0000115>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1428</obo:IAO_0000233>
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<obo:IAO_0000115 xml:lang="en">A lung microbiology datum that is about a virus.</obo:IAO_0000115>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1428</obo:IAO_0000233>
<rdfs:label>virus in lung datum</rdfs:label>
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<obo:IAO_0000111>mosquito membrane feeding device</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A device that contains blood in a membrane penetrable to mosquitoes, designed to feed mosquitoes without the need for an animal host.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1439</obo:IAO_0000233>
<rdfs:label>mosquito membrane feeding device</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003290 -->
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<obo:IAO_0000111>mosquito membrane feeding assay</obo:IAO_0000111>
<obo:IAO_0000112>Testing the effectiveness of drugs or antibodies against parasite transmission.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that evaluates host-to-mosquito transmission of a parasite organism by feeding a specimen of host blood infected with the parasite organism to a collection of mosquitoes through a mosquito membrane feeding device and, after a given time, dissecting the mosquitoes and counting the number of parasite organisms within them.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1439</obo:IAO_0000233>
<rdfs:label>mosquito membrane feeding assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003291 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003291">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
<obo:IAO_0000111>in silico design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design that is executed primarily on a computer.</obo:IAO_0000115>
<obo:IAO_0000117>Hector Guzman-Orozco</obo:IAO_0000117>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/In_silico</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1430</obo:IAO_0000233>
<obo:IAO_0000234>CMI-PB</obo:IAO_0000234>
<rdfs:label>in silico design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003292 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003292">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003115"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003320"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
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</owl:someValuesFrom>
</owl:Restriction>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001810"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003115"/>
<obo:IAO_0000111>cytometric bead array assay measuring epitope specific granulysin release by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometric bead array assay that detects epitope specific granulysin release by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>granulysin release|cytometric bead array</obo:OBI_9991118>
<rdfs:label>cytometric bead array assay measuring epitope specific granulysin release by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003293 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003293">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003115"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003317"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
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</owl:Restriction>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001497"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003115"/>
<obo:IAO_0000111>cytometric bead array assay measuring epitope specific perforin release by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometric bead array assay that detects epitope specific perforin release by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>perforin release|cytometric bead array</obo:OBI_9991118>
<rdfs:label>cytometric bead array assay measuring epitope specific perforin release by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003294 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003294">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002119"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0302887"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>modified acid-fast stain microscopy assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A microscopy assay that uses staining to identify acid-fast organisms in a specimen and does not require heating.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>NCIT:C85736</obo:IAO_0000119>
<obo:IAO_0000119>https://www.cdc.gov/dpdx/diagnosticprocedures/stool/staining.html</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1444</obo:IAO_0000233>
<rdfs:label>modified acid-fast stain microscopy assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003295 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003295">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003141"/>
<obo:IAO_0000111>positive binding datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A categorical binding datum that states that there is a significant disposition of two or more entities to form a complex.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Hector Guzman-Orozco</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>positive binding datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003296 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003296">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000655"/>
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<obo:IAO_0000111>antibodies from lymphocyte secretions assay</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 11329444.Clin Diagn Lab Immunol. 2001 May. Development of a Novel In Vitro Assay (ALS Assay) for Evaluation of Vaccine-Induced Antibody Secretion from Circulating Mucosal Lymphocytes.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that evaluates a blood specimen for antibodies currently being produced by lymphocytes in the specimen, by separating peripheral blood mononuclear cells, culturing them, and then collecting the supernatant containing the antibodies secreted from those cells.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000118>ALS assay</obo:IAO_0000118>
<obo:IAO_0000118>antibodies from lymphocyte supernatant assay</obo:IAO_0000118>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1443</obo:IAO_0000233>
<rdfs:label>antibodies from lymphocyte secretions assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003297 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003297">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000626"/>
<obo:IAO_0000111>tyramide signal amplification sequencing assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A DNA sequencing assay that uses tyramide signal amplification (TSA) to assess distance of DNA regions to a targeted nuclear compartment or protein, typically on a scale of 100-1000 nm.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>TSA-seq</obo:IAO_0000118>
<obo:IAO_0000119>EFO:0009971</obo:IAO_0000119>
<obo:IAO_0000119>PMID:30154186</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1472</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-4DN</obo:IAO_0000234>
<rdfs:label>tyramide signal amplification sequencing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003298 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003298">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>DNA adenine methyltransferase identification assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay for identifying DNA binding sites for a protein by fusing it to Dam methylase, and expressing it so that bound DNA gets methylated. The methylated DNA can then be isolated and analyzed.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>DamID assay</obo:IAO_0000118>
<obo:IAO_0000119>EFO:0008704</obo:IAO_0000119>
<obo:IAO_0000119>PMID:17545983</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1472</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-4DN</obo:IAO_0000234>
<rdfs:label>DNA adenine methyltransferase identification assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003299 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003299">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003298"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
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</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>DamID-seq</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A DNA adenine methyltransferase identification (DamID) assay in which DamID-generated DNA fragments undergo high-throughput sequencing to determine a protein's DNA-binding site.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000119>4DN DCIC</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1472</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-4DN</obo:IAO_0000234>
<rdfs:label>DamID-seq</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003300 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003300">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000626"/>
<obo:IAO_0000111>nucleolus-associated domain sequencing assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A DNA sequencing assay in which nucleoli are isolated and the DNA associated with them is sequenced to identify nucleoli-associating domains.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>NAD-seq</obo:IAO_0000118>
<obo:IAO_0000119>EFO:0009972</obo:IAO_0000119>
<obo:IAO_0000119>PMID:31201210</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1472</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-4DN</obo:IAO_0000234>
<rdfs:label>nucleolus-associated domain sequencing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003301 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003301">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002440"/>
<obo:IAO_0000111>DNase Hi-C assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A Hi-C assay in which DNase I is used for digesting DNA fragments rather than a restriction enzyme, which can result in a higher resolution of mapped chromosome contacts.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000119>EFO:0009976</obo:IAO_0000119>
<obo:IAO_0000119>PMID:27685100</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1472</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-4DN</obo:IAO_0000234>
<rdfs:label>DNase Hi-C assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003302 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003302">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002440"/>
<obo:IAO_0000111>micro-C assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A Hi-C assay which uses micrococcal nuclease digestion in place of the restriction enzyme digestion step.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000119>EFO:0008808</obo:IAO_0000119>
<obo:IAO_0000119>PMID:26119342</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1472</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-4DN</obo:IAO_0000234>
<rdfs:label>micro-C assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003303 -->
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<obo:IAO_0000111>single cell combinatorial indexing Hi-C assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A Hi-C assay performed on massively multiplexed single-cell samples.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>sci-Hi-C</obo:IAO_0000118>
<obo:IAO_0000119>EFO:0009977</obo:IAO_0000119>
<obo:IAO_0000119>PMID:28135255</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1472</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-4DN</obo:IAO_0000234>
<rdfs:label>single cell combinatorial indexing Hi-C assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003304 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003304">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002440"/>
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<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A Hi-C assay performed on isolated nuclei.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>sn-Hi-C</obo:IAO_0000118>
<obo:IAO_0000119>EFO:0009978</obo:IAO_0000119>
<obo:IAO_0000119>PMID:28355183</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1472</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-4DN</obo:IAO_0000234>
<rdfs:label>single nucleus Hi-C assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003305 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003305">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002440"/>
<obo:IAO_0000111>single cell Hi-C assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A Hi-C assay performed on a single cell.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000119>EFO:0009979</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1472</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-4DN</obo:IAO_0000234>
<rdfs:label>single cell Hi-C assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003306 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003306">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002440"/>
<obo:IAO_0000111>bulk Hi-C assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A Hi-C assay in which the sample that is sequenced is derived from a collection of cells, such as a tissue sample or entire cell culture, and therefore provides results representative of the aggregate of sample cells.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000119>4DN DCIC</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1472</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-4DN</obo:IAO_0000234>
<rdfs:label>bulk Hi-C assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003307 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003307">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002440"/>
<obo:IAO_0000111>multi-contact Hi-C assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A Hi-C assay that assesses interactions between multiple DNA fragments rather than only pairwise interactions as in traditional Hi-C. The experimental procedure of cross-linking, digestion, and ligation is performed similarly to traditional Hi-C, but after DNA is purified a long-read library is produced in which many ligated fragments may be contained in a single molecule. The library is then sequenced on a long read sequencer.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>MC-3C</obo:IAO_0000118>
<obo:IAO_0000118>MC-HI-C</obo:IAO_0000118>
<obo:IAO_0000119>The 4D Nucleome Network</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1472</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-4DN</obo:IAO_0000234>
<rdfs:label>multi-contact Hi-C assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003309 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003309">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000626"/>
<obo:IAO_0000111>transposase-mediated analysis of chromatin looping assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A DNA sequencing assay designed to detect interacting genomic regions. Rather than the traditional Hi-C approach of digestion and proximity ligation, the procedure involves transposase-mediated insertion of an oligonucleotide linker between the pair of interacting regions.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>TrAC-Loop</obo:IAO_0000118>
<obo:IAO_0000119>EFO:0009982</obo:IAO_0000119>
<obo:IAO_0000119>PMID:30150754</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1472</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-4DN</obo:IAO_0000234>
<rdfs:label>transposase-mediated analysis of chromatin looping assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003310 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003310">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600047"/>
<obo:IAO_0000111>split-pool recognition of interactions and tag extension assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A sequencing assay designed to detect multi-way interactions between nucleic acids. The procedure involves crosslinking nuclei, and then splitting the lysate among wells in a 96-well or other multi-well plate. A different barcode is ligated to the fragments in each well, and the lysates are pooled together again. This sequence of splitting, tagging, and re-combining is repeated several times so that fragments with the same sequences of barcodes represent fragments that have co-associated throughout the experiment. Finally, a sequencing library is constructed and high-throughput sequencing is performed.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>SPRITE</obo:IAO_0000118>
<obo:IAO_0000119>EFO:0009984</obo:IAO_0000119>
<obo:IAO_0000119>PMID:29887377</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1472</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-4DN</obo:IAO_0000234>
<rdfs:label>split-pool recognition of interactions and tag extension assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003311 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003311">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003310"/>
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<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A split-pool recognition of interactions and tag extension (SPRITE) assay that only assays interactions between regions of genomic DNA.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>DNA SPRITE</obo:IAO_0000118>
<obo:IAO_0000119>EFO:0009985</obo:IAO_0000119>
<obo:IAO_0000119>PMID:29887377</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1472</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-4DN</obo:IAO_0000234>
<rdfs:label>DNA split-pool recognition of interactions and tag extension assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003312 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003312">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003310"/>
<obo:IAO_0000111>RNA-DNA split-pool recognition of interactions and tag extension assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A split-pool recognition of interactions and tag extension (SPRITE) assay in which RNA in the cross-linked complexes is converted to cDNA before the initial splitting step, allowing analysis of RNA-DNA interactions.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>RNA-DNA SPRITE</obo:IAO_0000118>
<obo:IAO_0000119>EFO:0009986</obo:IAO_0000119>
<obo:IAO_0000119>PMID:29887377</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1472</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-4DN</obo:IAO_0000234>
<rdfs:label>RNA-DNA split-pool recognition of interactions and tag extension assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003313 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003313">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000626"/>
<obo:IAO_0000111>genome architecture mapping assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A DNA sequencing assay designed to analyze 3D chromatin structure without relying on digestion and ligation. The procedure involves cryosectioning samples in random orientation, and then single nuclear profiles are isolated by laser microdissection. Each nuclear profile then undergoes high-throughput sequencing, and subsequent analysis can generate a matrix of inferred proximity between genomic regions.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>GAM</obo:IAO_0000118>
<obo:IAO_0000119>EFO:0009987</obo:IAO_0000119>
<obo:IAO_0000119>PMID:28273065</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1472</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-4DN</obo:IAO_0000234>
<rdfs:label>genome architecture mapping assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003314 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003314">
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003368"/>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>mapping RNA-genome interactions assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A nuclear ligation assay for probing RNA-DNA interactions in the nucleus. Nuclei are crosslinked, and RNA fragments are ligated to proximal DNA fragments via a special linker molecule. After reverse transcription, high-throughput sequencing is performed.</obo:IAO_0000115>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>MARGI</obo:IAO_0000118>
<obo:IAO_0000119>EFO:0009988</obo:IAO_0000119>
<obo:IAO_0000119>PMID:28132817</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1472</obo:IAO_0000233>
<obo:IAO_0000234>CFDE-4DN</obo:IAO_0000234>
<rdfs:label>mapping RNA-genome interactions assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003315 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003315">
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<owl:Class>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110129"/>
<obo:IAO_0000111>assay measuring epitope specific amphiregulin production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A T cell epitope specific cytokine production assay that detects amphiregulin production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>amphiregulin release|biological activity</obo:OBI_9991118>
<rdfs:label>assay measuring epitope specific amphiregulin production by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003316 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003316">
<owl:equivalentClass>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003315"/>
<obo:IAO_0000111>ELISA measuring epitope specific amphiregulin production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An enzyme-linked immunosorbent assay that detects amphiregulin production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>amphiregulin release|ELISA</obo:OBI_9991118>
<rdfs:label>ELISA measuring epitope specific amphiregulin production by T cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003317 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0035944"/>
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<obo:IAO_0000111>perforin release during T cell degranulation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The release of perforin during cytotoxic T cell degranulation.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Hector Guzman-Orozco</obo:IAO_0000117>
<obo:IAO_0000119>Alexander Diehl, Bjoern Peters</obo:IAO_0000119>
<rdfs:label>perforin release during T cell degranulation</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003318 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003318">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0035746"/>
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<obo:IAO_0000111>granzyme A release during T cell degranulation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The release of granzyme A during cytotoxic T cell degranulation.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Hector Guzman-Orozco</obo:IAO_0000117>
<obo:IAO_0000119>Alexander Diehl, Bjoern Peters</obo:IAO_0000119>
<rdfs:label>granzyme A release during T cell degranulation</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003319 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003319">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0071613"/>
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<obo:IAO_0000111>granzyme B release during T cell degranulation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The release of granzyme B during cytotoxic T cell degranulation.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Hector Guzman-Orozco</obo:IAO_0000117>
<obo:IAO_0000119>Alexander Diehl, Bjoern Peters</obo:IAO_0000119>
<rdfs:label>granzyme B release during T cell degranulation</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003320 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003320">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0036262"/>
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<obo:IAO_0000111>granulysin release during T cell degranulation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
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<!-- http://purl.obolibrary.org/obo/OBI_0003336 -->
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<obo:IAO_0000111>functional magnetic resonance image data set</obo:IAO_0000111>
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<!-- http://purl.obolibrary.org/obo/OBI_0003337 -->
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<obo:IAO_0000112>An fMRI used for assessing functional connectivity of brain regions at rest.</obo:IAO_0000112>
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<!-- http://purl.obolibrary.org/obo/OBI_0003338 -->
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<!-- http://purl.obolibrary.org/obo/OBI_0003339 -->
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<obo:IAO_0000112>MRI used for evaluating ischemia.</obo:IAO_0000112>
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<!-- http://purl.obolibrary.org/obo/OBI_0003340 -->
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<rdfs:label>proton density magnetic resonance image data set</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003341 -->
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<!-- http://purl.obolibrary.org/obo/OBI_0003342 -->
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<obo:IAO_0000112>MRI used for assessing breakdown of blood brain barrier.</obo:IAO_0000112>
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<obo:IAO_0000115 xml:lang="en">A T1 weighted image data set where gadolidium contrast agent has been administered to the participant before image acquistion.</obo:IAO_0000115>
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<rdfs:label>post-Gd T1 weighted magnetic resonance image data set</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003343 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003343">
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<!-- http://purl.obolibrary.org/obo/OBI_0003344 -->
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<!-- http://purl.obolibrary.org/obo/OBI_0003345 -->
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<!-- http://purl.obolibrary.org/obo/OBI_0003346 -->
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<obo:IAO_0000112>MRI acquired after the first scan as part of longitudinal study.</obo:IAO_0000112>
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<obo:IAO_0000115 xml:lang="en">A T1w image data set collected at a later time than the evaluant's first scan.</obo:IAO_0000115>
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<!-- http://purl.obolibrary.org/obo/OBI_0003347 -->
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<!-- http://purl.obolibrary.org/obo/OBI_0003348 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003348">
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<!-- http://purl.obolibrary.org/obo/OBI_0003349 -->
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<obo:IAO_0000112>MRI used for visualizing lesions in multiple sclerosis.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A T2 weighted image data set collected using a FLAIR sequence.</obo:IAO_0000115>
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<rdfs:label>T2 weighted FLAIR magnetic resonance image data set</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003350 -->
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<obo:IAO_0000112>MRI used for visualizing structure of tissue with fast acquisition times.</obo:IAO_0000112>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1481</obo:IAO_0000233>
<rdfs:label>T2 weighted FSE magnetic resonance image data set</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003351 -->
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<!-- http://purl.obolibrary.org/obo/OBI_0003352 -->
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1481</obo:IAO_0000233>
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<obo:IAO_0000115 xml:lang="en">An image data set consisting of values computed from multiple image data sets encoded to represent the spatial location of individual functional or structural regions of a canonical brain.</obo:IAO_0000115>
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<obo:IAO_0000111>probabilistic brain region atlas image dataset</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A brain atlas consisting of weighted values that respresent the probability that a voxel X is part of some brain component Y, typically derived from multiple image data sets.</obo:IAO_0000115>
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<rdfs:label>probabilistic brain region atlas image dataset</rdfs:label>
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<obo:IAO_0000111>deterministic brain region atlas image data set</obo:IAO_0000111>
<obo:IAO_0000112>The JHU white-matter tractography atlas used for mapping brain connectomes.</obo:IAO_0000112>
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<rdfs:label>deterministic brain region atlas image data set</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003360 -->
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<obo:IAO_0000111>image segmentation map</obo:IAO_0000111>
<obo:IAO_0000112>The output of an algorithm that identifies pedestrians walking in a street from an image data set, where the output contains values only in the segment where the pedestrian is present.</obo:IAO_0000112>
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<obo:IAO_0000115 xml:lang="en">An image data set of integer values in which each value corresponds to some shared characteristic or computed property. The values often belong to a group of pixels or voxels that share the same characteristic, such as a tissue type or anatomical region.</obo:IAO_0000115>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1481</obo:IAO_0000233>
<rdfs:label>image segmentation map</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003361 -->
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<obo:IAO_0000111>lesion mask</obo:IAO_0000111>
<obo:IAO_0000112>The output produced by a manual or automated segmentation of lesions from a brain MRI.</obo:IAO_0000112>
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<rdfs:label>lesion mask</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003362 -->
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<obo:IAO_0000112>The output produced by a manual or automated segmentation of lesions from a T1w MRI.</obo:IAO_0000112>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1481</obo:IAO_0000233>
<rdfs:label>T1 lesion mask</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003363 -->
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<obo:IAO_0000112>The output produced by a manual or automated segmentation of lesions from a T2w FLAIR MRI.</obo:IAO_0000112>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1481</obo:IAO_0000233>
<rdfs:label>T2 FLAIR lesion mask</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003365 -->
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<obo:IAO_0000115 xml:lang="en">A data item that is the specified output of a milk assay.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
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<rdfs:label>milk assay datum</rdfs:label>
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<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1505</obo:IAO_0000233>
<rdfs:label xml:lang="en">organism diagnostic process</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003367 -->
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<obo:IAO_0000115 xml:lang="en">A conclusion based on data about that an organism has a disease, disorder, or syndrome of a certain type, or none of these.</obo:IAO_0000115>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1505</obo:IAO_0000233>
<rdfs:label xml:lang="en">diagnosis of an organism</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003368 -->
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<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Hector Guzman-Orozco</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1488</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1456</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
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<obo:IAO_0000115 xml:lang="en">A biological process where T cells produce XCL1 resulting from the recognition of a T cell epitope.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
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<!-- http://purl.obolibrary.org/obo/OBI_0003372 -->
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<obo:IAO_0000111>assay measuring epitope specific lymphotactin production by T cells</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A T cell epitope specific cytokine production assay that detects lymphotactin production by T cells.</obo:IAO_0000115>
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<rdfs:label>assay measuring epitope specific lymphotactin production by T cells</rdfs:label>
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<obo:IAO_0000115 xml:lang="en">A specimen that is derived from placental blood.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
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<obo:IAO_0000115 xml:lang="en">A blood microbiology assay that detects microorganisms in a placental blood specimen.</obo:IAO_0000115>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1297</obo:IAO_0000233>
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<obo:IAO_0000115 xml:lang="en">An organism detection datum that is the specified output of a placental blood microbiology assay.</obo:IAO_0000115>
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<obo:IAO_0000115 xml:lang="en">A placental blood microbiology datum that is about eukaryota.</obo:IAO_0000115>
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<obo:IAO_0000115 xml:lang="en">A material component separation process where a synaptic terminal is isolated from a neuron by mild homogenization of nervous tissue under isotonic conditions and subsequent fractionation using differential and density gradient centrifugation.</obo:IAO_0000115>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1546</obo:IAO_0000233>
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<obo:IAO_0000115 xml:lang="en">A DNA microarray manufactured with Agilent 60-mer SurePrint Technology .The SurePrint G3 Mouse Gene Expression 4x44K v2 Microarray provide full coverage of the mouse transcriptome using the latest annotation databases, including long non-coding RNA(lncRNA). Each glass slide is formatted with four high-definition 44K arrays.</obo:IAO_0000115>
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<obo:IAO_0000115 xml:lang="en">A DNA microarray manufactured with Agilent 60-mer SurePrint Technology for studying exon-level gene expression changes. The SurePrint G3 Mouse Exon 4x180K Microarray include probes targeting individual exons. Each glass slide formatted with four 180K arrays.</obo:IAO_0000115>
<obo:IAO_0000117>Jain Aluvathingal</obo:IAO_0000117>
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<obo:IAO_0000115 xml:lang="en">A DNA microarray manufactured with Agilent 60-mer SurePrint technology which provides comprehensive coverage of genes and transcripts using the latest annotation databases. The SurePrint G3 Mouse Gene Expression 8x60K v2 Microarray features complete coverage of established RefSeq coding transcripts (NM) from the latest build and updated long non-coding RNA (lncRNA) content to ensure relevant research.Each glass slide formatted with eight high-definition 60K arrays.</obo:IAO_0000115>
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<obo:IAO_0000117>Jain Aluvathingal</obo:IAO_0000117>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>GeneChip Mouse Gene 1.0 ST Array</obo:IAO_0000118>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1546</obo:IAO_0000233>
<obo:IAO_0000234>gEAR</obo:IAO_0000234>
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<obo:IAO_0000115 xml:lang="en">A DNA microarray manufactured by Affymetrix, which is a whole-transcript array that includes probes to measure both messenger (mRNA) and long intergenic non-coding RNA transcripts (lincRNA).To supplement the lincRNA data contained in RefSeq, we used sequence and transcript data from lncRNA db.</obo:IAO_0000115>
<obo:IAO_0000117>Jain Aluvathingal</obo:IAO_0000117>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>GeneChip Mouse Gene 2.1 ST Array</obo:IAO_0000118>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1546</obo:IAO_0000233>
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<obo:IAO_0000111>Affymetrix Rhesus Macaque Genome Array</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A DNA microarray manufactured by Affymetrix,which is a single-labeled high-density oligonucleotide array, designed to study gene expression in the rhesus animal model and to interrogate rhesus transcripts orthologous to the 3' end of human transcripts. The array consists of over 52,000 probe sets representing more than 20,000 genes, and several relevant viral organisms for studying host-disease immune response.</obo:IAO_0000115>
<obo:IAO_0000117>Jain Aluvathingal</obo:IAO_0000117>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>GeneChip Rhesus Macaque Genome Array</obo:IAO_0000118>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1546</obo:IAO_0000233>
<obo:IAO_0000234>gEAR</obo:IAO_0000234>
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<obo:IAO_0000115 xml:lang="en">A DNA microarray manufactured by Affymetrix, to go beyond gene-level expression profiling to accurately detect all known transcript isoforms produced by a gene. The array design covers >245,000 coding transcripts, >40,000 non-coding transcripts and >339,000 probe sets covering exon-exon junctions, thus ensuring uniform coverage of the transcriptome.</obo:IAO_0000115>
<obo:IAO_0000117>Jain Aluvathingal</obo:IAO_0000117>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>GeneChip Human Transcriptome Array 2.0</obo:IAO_0000118>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1546</obo:IAO_0000233>
<obo:IAO_0000234>gEAR</obo:IAO_0000234>
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<obo:IAO_0000111>Affymetrix Human Genome U219 Array</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A DNA microarray manufactured by Affymetrix, which comprises more than 530,000 probes covering more than 36,000 transcripts and variants, which represent more than 20,000 genes mapped through RefSeq or via UniGene annotation. Sequences used in the design of the array were selected from the RefSeq version 36, UniGene database 219, and full-length human mRNAs from GenBank™.</obo:IAO_0000115>
<obo:IAO_0000117>Jain Aluvathingal</obo:IAO_0000117>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000118>Applied Biosystems GeneChip PrimeView Human Gene Expression Array</obo:IAO_0000118>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1546</obo:IAO_0000233>
<obo:IAO_0000234>gEAR</obo:IAO_0000234>
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<obo:IAO_0000115 xml:lang="en">A DNA microarray manufactured by Affymetrix, which provides the most accurate, sensitive, and comprehensive measurement of protein coding (mRNA) and long intergenic non-coding RNA (lincRNA) transcripts. The array design covers >33,500 coding transcripts and >11,000 lincRNA transcripts thus enabling researchers to understand whole-transcriptome gene expression at the gene and exon levels, which allows the study of transcript variants and alternative splicing events.</obo:IAO_0000115>
<obo:IAO_0000117>Jain Aluvathingal</obo:IAO_0000117>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1546</obo:IAO_0000233>
<obo:IAO_0000234>gEAR</obo:IAO_0000234>
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<obo:IAO_0000115 xml:lang="en">A DNA microarray manufactured by Affymetrix, to obtain a gene-level view of the human transcriptome. The assay design covers >20,000 well-annotated genes, providing researchers with the ability to perform gene-level expression profiling studies, to identify expression biomarkers , and to quickly assess changes in key genes and pathways.</obo:IAO_0000115>
<obo:IAO_0000117>Jain Aluvathingal</obo:IAO_0000117>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
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<obo:IAO_0000115 xml:lang="en">A DNA microarray manufactured by Affymetrix, to obtain a gene-level view of the mouse transcriptome. The assay design covers >20,000 well-annotated genes, providing researchers with the ability to perform gene-level expression profiling studies, to identify expression biomarkers, and to quickly assess changes in key genes and pathways.</obo:IAO_0000115>
<obo:IAO_0000117>Jain Aluvathingal</obo:IAO_0000117>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1546</obo:IAO_0000233>
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<obo:IAO_0000111>Illumina HumanHT-12 V4.0 expression beadchip</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">An Illumina BeadChip which employs direct-hybridization assay, for whole-genome expression profiling and expression-based quantitative trait loci (eQTL) studies. This BeadChip contains 12 arrays, each featuring more than 48,000 probes, targeting more than 31,000 annotated genes, providing genome-wide coverage of well-characterized genes, gene candidates, and splice variants.</obo:IAO_0000115>
<obo:IAO_0000117>Jain Aluvathingal</obo:IAO_0000117>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000119>https://www.illumina.com/documents/products/technotes/technote_humanht_12_imputation.pdf</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1546</obo:IAO_0000233>
<obo:IAO_0000234>gEAR</obo:IAO_0000234>
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<obo:IAO_0000111>Illumina MouseRef-8 v2.0 beadchip</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An Illumina BeadChip which employs direct-hybridization assay, for whole-genome expression profiling in the mouse.This Beadchip contains 8 microarrays, featuring more than 25,000 probes per array, derived from the NCBI RefSeq database and supplemented with MEEBO and RIKEN FANTOM2 content.</obo:IAO_0000115>
<obo:IAO_0000117>Jain Aluvathingal</obo:IAO_0000117>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Suvarna Nadendla</obo:IAO_0000117>
<obo:IAO_0000119>https://support.illumina.com/content/dam/illumina-support/documents/documentation/chemistry_documentation/arraykits/whole-genome-gene-expression/WGGEX_Direct_Hybridization_Assay_Guide_11322355_A.pdf, https://www.illumina.com/documents/products/datasheets/datasheet_gene_exp_analysis.pdf</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1546</obo:IAO_0000233>
<obo:IAO_0000234>gEAR</obo:IAO_0000234>
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<obo:IAO_0000115 xml:lang="en">A DNA microarray manufactured by Affymetrix, used to identify exon-exon junctions associated with alternate splice variants in the mouse transcriptome.</obo:IAO_0000115>
<obo:IAO_0000117>Jain Aluvathingal</obo:IAO_0000117>
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<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000119>Michelle Giglio</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1559</obo:IAO_0000233>
<obo:IAO_0000234>CFDE</obo:IAO_0000234>
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<obo:IAO_0000111>administering substance in vivo to cause disease</obo:IAO_0000111>
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<obo:IAO_0000117>IEDB</obo:IAO_0000117>
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<obo:IAO_0000115 xml:lang="en">An administration of substance in vivo with the intention to reduce the symptoms of or prevent development of a disease in the organism.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>administering substance in vivo to reduce or prevent disease</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003415 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003415">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000655"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_2000001"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000655"/>
<obo:IAO_0000111>peripheral blood mononuclear cell specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A processed specimen that is extracted from whole blood using gradient centrifugation that separates the blood into a layer of peripheral blood mononuclear cells under the top layer of plasma. It contains lymphocytes, monocytes or macrophages that are critical components in the immune system.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000118>PBMC specimen</obo:IAO_0000118>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Peripheral_blood_mononuclear_cell</obo:IAO_0000119>
<rdfs:label>peripheral blood mononuclear cell specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003416 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003416">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000408"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000221"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/PATO_0000122"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000080"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001460"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>mid-upper arm circumference datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A length measurement datum that is the specified output of an assay measuring the length around an upper arm, taken midway along the upper arm.</obo:IAO_0000115>
<obo:IAO_0000119>The Mother and Child Health and Education Trust</obo:IAO_0000119>
<rdfs:label>mid-upper arm circumference datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003417 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003417">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000027"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002145"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
<obo:IAO_0000111>antigen specific antibodies assay datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A data item that is the specified output of an antigen specific antibodies assay.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins ORCID:0000-0001-6595-0902</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1526</obo:IAO_0000233>
<rdfs:label>antigen specific antibodies assay datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003418 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003418">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002145"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000655"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000655"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>antigen specific antibodies in blood assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An antigen specific antibodies assay that has a blood specimen as evaluant.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins ORCID:0000-0001-6595-0902</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1526</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>antigen specific antibodies in blood assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003419 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003419">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002145"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003236"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002505"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002505"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>antigen specific antibodies in milk assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An antigen specific antibodies assay that has a milk specimen as evaluant.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins ORCID:0000-0001-6595-0902</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1526</obo:IAO_0000233>
<obo:IAO_0000234>VEuPathDB</obo:IAO_0000234>
<rdfs:label>antigen specific antibodies in milk assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003420 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003420">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003417"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003243"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003417"/>
<obo:IAO_0000111>antigen specific antibodies in blood assay datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An antigen specific antibodies assay datum that is the specified output of an antigen specific antibodies in blood assay.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins ORCID:0000-0001-6595-0902</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1526</obo:IAO_0000233>
<rdfs:label>antigen specific antibodies in blood assay datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003421 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003421">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003417"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0003236"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003365"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003417"/>
<obo:IAO_0000111>antigen specific antibodies in milk assay datum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An antigen specific antibodies assay datum that is the specified output of an antigen specific antibodies in milk assay.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins ORCID:0000-0001-6595-0902</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1526</obo:IAO_0000233>
<rdfs:label>antigen specific antibodies in milk assay datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003422 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003422">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0003824"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>enzymatic activity level assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An assay in which the level of catalytic activity of an enzyme is determined.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>enzymatic activity level assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003423 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003423">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003422"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0008253"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003422"/>
<obo:IAO_0000111>5'-nucleotidase activity level assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An enzymatic activity level assay that measures the activity of 5'-nucleotidase in a sample.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>5'-nucleotidase activity level assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003424 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003424">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003422"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0004021"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003422"/>
<obo:IAO_0000111>alanine aminotransferase activity level assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An enzymatic activity level assay that measures the activity of alanine aminotransferase in a sample.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>alanine aminotransferase activity level assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003425 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003425">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003422"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0004035"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003422"/>
<obo:IAO_0000111>alkaline phosphatase activity level assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An enzymatic activity level assay that measures the activity of alkaline phosphatase in a sample.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>alkaline phosphatase activity level assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003426 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003426">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003422"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0016160"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003422"/>
<obo:IAO_0000111>amylase activity level assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An enzymatic activity level assay that measures the activity of amylase in a sample.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>amylase activity level assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003427 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003427">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003422"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0004069"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003422"/>
<obo:IAO_0000111>aspartate aminotransferase activity level assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An enzymatic activity level assay that measures the activity of aspartate aminotransferase in a sample.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>aspartate aminotransferase activity level assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003428 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003428">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003422"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0004104"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003422"/>
<obo:IAO_0000111>cholinesterase activity level assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An enzymatic activity level assay that measures the activity of cholinesterase in a sample.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>cholinesterase activity level assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003429 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003429">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003422"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0004111"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003422"/>
<obo:IAO_0000111>creatine kinase activity level assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An enzymatic activity level assay that measures the activity of creatine kinase in a sample.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>creatine kinase activity level assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003430 -->
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0047823"/>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003422"/>
<obo:IAO_0000111>gamma-glutamyltransferase activity level assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An enzymatic activity level assay that measures the activity of gamma-glutamyltransferase in a sample.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>gamma-glutamyltransferase activity level assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003431 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003422"/>
<obo:IAO_0000111>glutamate dehydrogenase activity level assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An enzymatic activity level assay that measures the activity of glutamate dehydrogenase in a sample.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>glutamate dehydrogenase activity level assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003432 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003422"/>
<obo:IAO_0000111>isocitrate dehydrogenase activity level assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An enzymatic activity level assay that measures the activity of isocitrate dehydrogenase in a sample.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>isocitrate dehydrogenase activity level assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003433 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003433">
<owl:equivalentClass>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0004457"/>
</owl:Restriction>
</owl:someValuesFrom>
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</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003422"/>
<obo:IAO_0000111>lactate dehydrogenase activity level assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An enzymatic activity level assay that measures the activity of lactate dehydrogenase in a sample.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>lactate dehydrogenase activity level assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003434 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003434">
<owl:equivalentClass>
<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0003939"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003422"/>
<obo:IAO_0000111>sorbitol dehydrogenase activity level assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An enzymatic activity level assay that measures the activity of sorbitol dehydrogenase in a sample.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>sorbitol dehydrogenase activity level assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003435 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003435">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0003997"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003422"/>
<obo:IAO_0000111>acyl-CoA oxidase activity level assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An enzymatic activity level assay that measures the activity of Acyl-CoA oxidase in a sample.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>acyl-CoA oxidase activity level assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003436 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003436">
<owl:equivalentClass>
<owl:Class>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003422"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0016231"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003422"/>
<obo:IAO_0000111>N-acetyl-beta-glucosaminidase activity level assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An enzymatic activity level assay that measures the activity of N-acetyl-beta-glucosaminidase in a sample.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>N-acetyl-beta-glucosaminidase activity level assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003437 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003437">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003422"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0004540"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003422"/>
<obo:IAO_0000111>ribonuclease activity level assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An enzymatic activity level assay that measures the activity of ribonuclease in a sample.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>ribonuclease activity level assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003438 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003438">
<owl:equivalentClass>
<owl:Class>
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<owl:someValuesFrom>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0015925"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003422"/>
<obo:IAO_0000111>galactosidase activity level assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An enzymatic activity level assay that measures the activity of galactosidase in a sample.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<rdfs:label>galactosidase activity level assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003454 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003454">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002920"/>
<obo:IAO_0000111>Mosquito Magnet Liberty Plus trap</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An arthropod trap that is designed to emit a combination of carbon dioxide, heat, water, and oct-1-en-3-ol attractants while simultaneously using suction to trap arthropods. This trap has the same design as the Mosquito Magnet Pro trap but is smaller, is more lightweight, and uses a main line electricity supply instead of propane to power itself. Both use propane to produce the arthropod attractor.</obo:IAO_0000115>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1523</obo:IAO_0000233>
<rdfs:label>Mosquito Magnet Liberty Plus trap</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003455 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003455">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003456"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000319"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0001064"/>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000444"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100026"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000725"/>
</owl:Restriction>
</owl:intersectionOf>
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<obo:IAO_0000111>tumor challenge</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The administration of a malignant cell to a host.</obo:IAO_0000115>
<obo:IAO_0000117>Hector Guzman-Orozco</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>tumor challenge</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003456 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003456">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600007"/>
<obo:IAO_0000111>in vivo challenge</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The administration of a challenge to a live host.</obo:IAO_0000115>
<obo:IAO_0000117>Hector Guzman-Orozco</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>in vivo challenge</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003457 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003457">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001179"/>
<obo:IAO_0000111>epitope protection from infectious challenge experiment based on survival</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An epitope protection from infectious challenge experiment that determines the success of the epitope intervention based on increased survival of the host compared to controls.</obo:IAO_0000115>
<obo:IAO_0000117>Hector Guzman-Orozco</obo:IAO_0000117>
<obo:IAO_0000118>survival after infectious challenge</obo:IAO_0000118>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1594</obo:IAO_0000233>
<rdfs:label>epitope protection from infectious challenge experiment based on survival</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003458 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003458">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001183"/>
<obo:IAO_0000111>epitope protection from tumor challenge experiment based on burden</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An epitope protection from tumor challenge experiment in which the readout is a reduction in the presence of malignant cells in the host compared to controls.</obo:IAO_0000115>
<obo:IAO_0000117>Hector Guzman-Orozco</obo:IAO_0000117>
<obo:IAO_0000118>burden after tumor challenge</obo:IAO_0000118>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1594</obo:IAO_0000233>
<rdfs:label>epitope protection from tumor challenge experiment based on burden</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003459 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003459">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001183"/>
<obo:IAO_0000111>epitope protection from tumor challenge experiment based on survival</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An epitope protection from tumor challenge experiment that determines the success of the epitope intervention based on increased survival of the host compared to controls.</obo:IAO_0000115>
<obo:IAO_0000117>Hector Guzman-Orozco</obo:IAO_0000117>
<obo:IAO_0000118>survival after tumor challenge</obo:IAO_0000118>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1594</obo:IAO_0000233>
<rdfs:label>epitope protection from tumor challenge experiment based on survival</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003460 -->
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_33208"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0001421"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
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</owl:Restriction>
</owl:someValuesFrom>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002073"/>
<obo:IAO_0000111>in vivo assay measuring T cell epitope specific protection from pathogen challenge</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An in vivo assay measuring T cell epitope specific protection from pathogen challenge.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>protection from pathogen challenge|in vivo assay</obo:OBI_9991118>
<rdfs:label>in vivo assay measuring T cell epitope specific protection from pathogen challenge</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003461 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003461">
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<obo:IAO_0000115 xml:lang="en">A specimen that is derived from part of a digestive tract.</obo:IAO_0000115>
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<rdfs:label>digestive tract specimen</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003484 -->
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<obo:IAO_0000115 xml:lang="en">A T cell epitope specific cytokine production assay that detects interleukin-25 production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>IL-25 release|biological activity</obo:OBI_9991118>
<rdfs:label>assay measuring epitope specific interleukin-25 production by T cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003485 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003484"/>
<obo:IAO_0000111>detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-25 production by T cells</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A detection of specific nucleic acid polymers with complementary probes that detects interleukin-25 production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>IL-25 release|RNA/DNA detection</obo:OBI_9991118>
<rdfs:label>detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-25 production by T cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003486 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003484"/>
<obo:IAO_0000111>intracellular cytokine staining assay measuring epitope specific interleukin-25 production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A flow cytometry assay that detects interleukin-25 production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>IL-25 release|ICS</obo:OBI_9991118>
<rdfs:label>intracellular cytokine staining assay measuring epitope specific interleukin-25 production by T cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003487 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003484"/>
<obo:IAO_0000111>ELISA measuring epitope specific interleukin-25 production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An enzyme-linked immunosorbent assay that detects interleukin-25 production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>IL-25 release|ELISA</obo:OBI_9991118>
<rdfs:label>ELISA measuring epitope specific interleukin-25 production by T cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003488 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001400"/>
<obo:IAO_0000111>cell culture analyte detection bioassay measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A reporter cell line analyte detection bioassay that detects tumor necrosis factor superfamily cytokine production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>TNF release|bioassay</obo:OBI_9991118>
<rdfs:label>cell culture analyte detection bioassay measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003489 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003489">
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<obo:IAO_0000111>Scrub Typhus Detect IgM ELISA kit</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay kit that is manufactured by InBios International to use ELISA to test for IgM antibodies for Orientia tsutsugamushi strains Karp, Kato, Gilliam, and TA 716, with a protein microarray that has a 96-well plate and the 56-kDa type-specific antigen.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins ORCID:0000-0001-6595-0902</obo:IAO_0000117>
<obo:IAO_0000119>https://inbios.com/scrub-typhus-detecttm-igm-elisa-kit-intl/</obo:IAO_0000119>
<rdfs:label>Scrub Typhus Detect IgM ELISA kit</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003490 -->
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<obo:IAO_0000111>Panbio Dengue IgM capture ELISA kit</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An assay kit that is manufactured by Abbott to test for IgM antibodies for Dengue with a two-plate protein microarray. One plate contains stabilized Dengue viruses 1 through 4, and the other plate contains anti-human IgM antibody.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins ORCID:0000-0001-6595-0902</obo:IAO_0000117>
<rdfs:label>Panbio Dengue IgM capture ELISA kit</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003491 -->
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</rdfs:subClassOf>
<obo:IAO_0000111>Panbio Dengue Early ELISA kit</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An assay kit that is manufactured by Abbott to detect the NS1 Dengue viral protein with a protein microarray and an anti-NS1 monoclonal antibody.</obo:IAO_0000115>
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<rdfs:label>Panbio Dengue Early ELISA kit</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003492 -->
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<obo:IAO_0000111>SD Bioline Chikungunya IgM RDT kit</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device manufactured by Abbott for rapid detection of human IgM antibodies for Chikungunya virus in blood, using analytical chromatography.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins ORCID:0000-0001-6595-0902</obo:IAO_0000117>
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<rdfs:label>SD Bioline Chikungunya IgM RDT kit</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003493 -->
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<obo:IAO_0000111>SD Bioline Chikungunya IgM capture ELISA kit</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An assay kit that is manufactured by Abbott to detect human IgM antibodies for Chikungunya with a protein microarray and ELISA.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins ORCID:0000-0001-6595-0902</obo:IAO_0000117>
<rdfs:label>SD Bioline Chikungunya IgM capture ELISA kit</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003494 -->
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<obo:IAO_0000111>Advantage Chikungunya IgM Card kit</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An assay kit that is manufactured by J. Mitra to detect human IgM antibodies for Chikungunya virus with a protein microarray and double-antigen sandwich ELISA.</obo:IAO_0000115>
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<rdfs:label>Advantage Chikungunya IgM Card kit</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003498 -->
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<obo:IAO_0000111>organism detection assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that detects a type of organism and/or the quantity of individuals of a type of organism.</obo:IAO_0000115>
<obo:IAO_0000116>This term is a generalized version of the term previously known as 'organism identification assay', to include classification other than species and to include quantities as outputs.</obo:IAO_0000116>
<obo:IAO_0000117>John Judkins ORCID:0000-0001-6595-0902</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1633</obo:IAO_0000233>
<rdfs:label>organism detection assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003501 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003501">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002441"/>
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<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A physical examination of an organism's ability to perform functional activities.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
<rdfs:label>functional assessment of individual</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003502 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003502">
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001577"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000221"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBA_2060185"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>facial atrophy assessment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An observational assessment of the loss of facial muscle tissue due to inactivity or disease.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
<rdfs:label>facial atrophy assessment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003503 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003503">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003536"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001723"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000221"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBA_2060185"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>tongue atrophy assessment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An observational assessment of the loss of muscle tissue related to tongue movement due to inactivity or disease.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
<rdfs:label>tongue atrophy assessment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003504 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003504">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003501"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001103"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000221"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBA_2060185"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>forced cough assessment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A functional assessment of an individual's ability to cough forcefully.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
<rdfs:label>forced cough assessment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003505 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003505">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003501"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000165"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000221"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBA_2060185"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>speech test assessment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A functional assessment of an individual's ability to understandably repeat spoken sentences.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
<rdfs:label>speech test assessment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003506 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003506">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003501"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002389"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000221"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBA_2060181"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>finger to finger assessment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A functional assessment of an individual's ability to touch index fingers together in front of the sternum without oscillation for a specified duration of time</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
<rdfs:label>finger to finger assessment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003507 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003507">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003501"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001460"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000221"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBA_2060181"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>nose to finger assessment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A functional assessment of an individual's ability to touch their own nose and then touch an examiners finger in front of them and then touch their own nose once more.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
<rdfs:label>nose to finger assessment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003508 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003508">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003501"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001460"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000221"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBA_2060181"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>dysmetria assessment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A functional assessment of an individual's ability to accurately touch a moving target with their finger and then touch their own chin a number of times in a row.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
<rdfs:label>dysmetria assessment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003509 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003509">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003501"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002386"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000221"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBA_2060181"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>rapid alternating hands assessment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A functional assessment of an individual's ability to alternate the forearm between pronation and suppination as quickly as possible during a specified duration of time</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
<rdfs:label>rapid alternating hands assessment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003510 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003510">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003501"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002389"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000221"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBA_2060181"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>finger taps assessment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A functional assessment of an individual's ability to touch their finger-tip to thumb as many times as possible during a specified duration of time.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
<rdfs:label>finger taps assessment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003511 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003511">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003501"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000978"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000221"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBA_2060182"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>heel along shin assessment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A functional assessment of an individual's ability to slide their heel back and forth along their contralateral tibia from the patella to the ankle with the contralateral leg extended.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
<rdfs:label>heel along shin assessment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003512 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003512">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003501"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000978"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000221"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBA_2060182"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>heel to shin assessment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A functional assessment of an individual's ability to tap their heel to the midpoint of the contralateral shin a number of times.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
<rdfs:label>heel to shin assessment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003513 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003513">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003536"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000010"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000221"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBA_2060186"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>muscle atrophy assessment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An observational assesment of an individual's muscle tissue loss due to inactivity or disease.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
<rdfs:label>muscle atrophy assessment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003514 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003514">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003501"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000010"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000221"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBA_2060186"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>muscle weakness assessment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A functional assessment of an individual's ability to perform muscle movement to overcome gravity or physical resistence.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
<rdfs:label>muscle weakness assessment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003515 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003515">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003501"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000010"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000221"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBA_2060186"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>vibratory sense assessment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A functional assessment of an individual's ability to sense vibration.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
<rdfs:label>vibratory sense assessment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003516 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003516">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003501"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000010"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000221"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBA_2060186"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>position sense assessment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A functional assessment of an individual's ability to sense the position of a finger or toe that has been manipulated by minimal random movements.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
<rdfs:label>position sense assessment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003517 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003517">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003501"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000010"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000221"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBA_2060186"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>deep tendon reflex assessment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A functional assessment of an individual's muscle contraction when a muscle is triggered by a signal from a muscle spindle in response to a stimulus applied to a specific trigger point on the body.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
<rdfs:label>deep tendon reflex assessment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003518 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003518">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003501"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000221"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBA_2060184"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>limits of stability assessment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The functional assessment of an individual's ability to maintain balance, posture or upright stability.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
<rdfs:label>limits of stability assessment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003519 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003519">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003518"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000221"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBA_2060184"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>sitting posture assessment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A limits of stability assessment designed to assess an individual's ability to maintain unsupported posture while sitting over a given time period.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
<rdfs:label>sitting posture assessment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003520 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003520">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003518"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000221"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBA_2060184"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>stance feet apart assessment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A limits of stability assessment designed to assess an individual's ability to maintain a stable stance with feet 20 cm apart.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
<rdfs:label>stance feet apart assessment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003521 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003521">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003518"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000221"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBA_2060184"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>stance feet apart assessment, with eyes closed</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A limits of stability assessment designed to assess an individual's ability to maintain a stable stance with their eyes closed.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
<rdfs:label>stance feet apart assessment, with eyes closed</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003522 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003522">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003518"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000221"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBA_2060184"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>stance feet together assessment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A limits of stability assessment designed to assess an individual's ability to maintain a stable stance with feet together.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
<rdfs:label>stance feet together assessment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003523 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003523">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003518"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000221"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBA_2060184"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>stance feet together assessment, with eyes closed</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A limits of stability assessment designed to assess an individual's ability to maintain a stable stance with feet together and eyes closed.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
<rdfs:label>stance feet together assessment, with eyes closed</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003524 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003524">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003518"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000221"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBA_2060184"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>tandem stance assessment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A limits of stability assessment designed to assess an individual's ability to maintain a stable stance with feet in tandem placement.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
<rdfs:label>tandem stance assessment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003525 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003525">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003518"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000221"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBA_2060184"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>stance on one foot assessment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A limits of stability assessment designed to assess an individual's ability to maintain a stable stance on one foot.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
<rdfs:label>stance on one foot assessment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003526 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003526">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003518"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000221"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBA_2060184"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>tandem walk assessment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A limits of stability assessment designed to assess an individual's ability to maintain balance while walking in a straight line placing steps in tandem.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
<rdfs:label>tandem walk assessment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003527 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003527">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003518"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000221"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBA_2060184"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>gait assessment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A limits of stability assessment designed to assess an individual's manner or pattern of walking.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
<rdfs:label>gait assessment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003528 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003528">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003501"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000221"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBA_2060185"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>bulbar assessment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A functional assessment of an individual's lower cranial nerve function via proxy of facial muscle performance.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
<rdfs:label>bulbar assessment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003529 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003529">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003501"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000221"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBA_2060185"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>spontaneous speech assessment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A functional assessment of an individual's ability to articulate spoken words.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
<rdfs:label>spontaneous speech assessment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003530 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003530">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003501"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000221"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBA_2060180"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>limb coordination assessment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A functional assessment of an individual's ability to coordinate limb movement.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_0003531 -->
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<obo:IAO_0000111>upper limb coordination assessment</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A limb coordination assessment designed to assess an individual's ability to coordinate upper limb movement.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
<rdfs:label>upper limb coordination assessment</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003532 -->
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<obo:IAO_0000111>lower limb coordination assessment</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A limb coordination assessment designed to assess an individual's ability to coordinate lower limb movement.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
<rdfs:label>lower limb coordination assessment</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003533 -->
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<obo:IAO_0000111>nervous system functionality assessment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A functional assesment of an individual's nerve performance. Specifically the nerves connecting the sensory and motor structures with the central nervous system.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
<rdfs:label>nervous system functionality assessment</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003534 -->
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<obo:IAO_0000111>upright stability assessment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A functional assessment of an individual's ability to maintain upright body posture.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
<rdfs:label>upright stability assessment</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003535 -->
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<obo:IAO_0000111>deep tendon reflex assessment of the knee joint</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A deep tendon reflex assessment of an individual's reaction to stimulus applied to a knee joint.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
<rdfs:label>deep tendon reflex assessment of the knee joint</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003536 -->
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<obo:IAO_0000111>observational assessment of individual</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A physical examination of an organism through visual assesment.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
<rdfs:label>observational assessment of individual</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003537 -->
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<obo:IAO_0000111>deep tendon reflex assessment of the ankle joint</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A deep tendon reflex assessment of an individual's reaction to stimulus applied to an ankle joint.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
<rdfs:label>deep tendon reflex assessment of the ankle joint</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003538 -->
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<obo:IAO_0000111>deep tendon reflex assessment of the tendon of biceps brachii</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A deep tendon reflex assessment of an individual's reaction to stimulus applied to a tendon of biceps brachii.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
<rdfs:label>deep tendon reflex assessment of the tendon of biceps brachii</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003539 -->
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<obo:IAO_0000111>deep tendon reflex assessment of the brachioradialis</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A deep tendon reflex assessment of an individual's reaction to stimulus applied to a brachioradialis.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Olson, ORCID: 0000-0002-8134-1207</obo:IAO_0000117>
<obo:IAO_0000119>Critical Path Institute</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1637</obo:IAO_0000233>
<rdfs:label>deep tendon reflex assessment of the brachioradialis</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003540 -->
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<obo:IAO_0000111>tandem mass spectrometry assay</obo:IAO_0000111>
<obo:IAO_0000112>A precursor ion is selected in the first stage, allowed to fragment and then all resultant masses are scanned in the second mass analyzer and detected in the detector that is positioned after the second mass analyzer. This experiment is commonly performed to identify transitions used for quantification by tandem MS.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A mass spectrometry assay that uses two or more analyzers separated by a region in which ions can be induced to fragment by transfer of energy (frequently by collision with other molecules).</obo:IAO_0000115>
<obo:IAO_0000116>Discussed on the OBI developer call 2022-03-07: 'tandem mass spectrometry' OBI:0200198 is under 'data transformation' but is actually defined like an assay. Moving OBI:0200198 from 'data transformation' to 'assay' is a major logical change, so the OBI development team supports obsoleting 'tandem mass spectrometry' OBI:0200198 and replacing it with ‘tandem mass spectrometry assay’ OBI:0003540.</obo:IAO_0000116>
<obo:IAO_0000117>Hector Guzman-Orozco, ORCID:0000-0003-3430-8997</obo:IAO_0000117>
<obo:IAO_0000119>http://purl.obolibrary.org/obo/OBI_0200198</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1506</obo:IAO_0000233>
<rdfs:label>tandem mass spectrometry assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003541 -->
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<obo:IAO_0000111>ELISA measuring Orientia tsutsugamushi IgM antibody</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An enzyme-linked immunosorbent assay that detects the IgM antibody that binds Orientia tsutsugamushi.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins ORCID:0000-0001-6595-0902</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1456</obo:IAO_0000233>
<rdfs:label>ELISA measuring Orientia tsutsugamushi IgM antibody</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003542 -->
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<obo:IAO_0000111>microarray assay measuring Dengue IgM antibody</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A microarray assay that detects the IgM antibody that binds Dengue.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins ORCID:0000-0001-6595-0902</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1456</obo:IAO_0000233>
<rdfs:label>microarray assay measuring Dengue IgM antibody</rdfs:label>
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<obo:IAO_0000111>microarray assay measuring NS1</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A microarray assay that detects NS1.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins ORCID:0000-0001-6595-0902</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1456</obo:IAO_0000233>
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<obo:IAO_0000111>analytical chromatography measuring Chikungunya IgM antibody</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Analytical chromatography that detects the IgM antibody that binds Chikungunya.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins ORCID:0000-0001-6595-0902</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1456</obo:IAO_0000233>
<rdfs:label>analytical chromatography measuring Chikungunya IgM antibody</rdfs:label>
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<obo:IAO_0000111>ELISA measuring Chikungunya IgM antibody</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An enzyme-linked immunosorbent assay that detects the IgM antibody that binds Chikungunya.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins ORCID:0000-0001-6595-0902</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1456</obo:IAO_0000233>
<rdfs:label>ELISA measuring Chikungunya IgM antibody</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003546 -->
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<obo:IAO_0000111>microarray ELISA measuring Chikungunya IgM antibody</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An enzyme-linked immunosorbent assay that uses a microarray as the solid support and detects the IgM antibody that binds Chikungunya.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins ORCID:0000-0001-6595-0902</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1456</obo:IAO_0000233>
<rdfs:label>microarray ELISA measuring Chikungunya IgM antibody</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003547 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003547">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600046"/>
<obo:IAO_0000111>liquid chromatography</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A preparative chromatography in which material components are separated in a liquid solution.</obo:IAO_0000115>
<obo:IAO_0000117>Hector Guzman-Orozco</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1685</obo:IAO_0000233>
<rdfs:label>liquid chromatography</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003548 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003548">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001933"/>
<obo:IAO_0000111>upper limit of detection</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A value specification that specifies the largest concentration/amount of a substance that can be quantified in an analyte assay.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Hector Guzman-Orozco</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1485</obo:IAO_0000233>
<rdfs:label>upper limit of detection</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003549 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003549">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001933"/>
<obo:IAO_0000111>lower limit of detection</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A value specification that specifies the smallest concentration/amount of a substance that can be detected in an analyte assay.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Hector Guzman-Orozco</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1485</obo:IAO_0000233>
<rdfs:label>lower limit of detection</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003550 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003550">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002926"/>
<obo:IAO_0000111>odor baited CDC light trap</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A CDC light trap that uses odorous gas from a human being as an attractant, by pumping it from the room where the human being sleeps into the trap.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins ORCID:0000-0001-6595-0902</obo:IAO_0000117>
<obo:IAO_0000118>human odour baited light trap</obo:IAO_0000118>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1654</obo:IAO_0000233>
<rdfs:label>odor baited CDC light trap</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003551 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003551">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002939"/>
<obo:IAO_0000111>resting clay pot trap</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A resting arthropod trap that consists of a container composed primarily of clay.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins ORCID:0000-0001-6595-0902</obo:IAO_0000117>
<obo:IAO_0000118>resting clay pot catch</obo:IAO_0000118>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1651</obo:IAO_0000233>
<rdfs:label>resting clay pot trap</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003552 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002439"/>
<obo:IAO_0000111>proximity ligation-assisted ChIP-seq</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A chromosome conformation capture assay in which proximity ligation is conducted in nuclei prior to chromatin shearing and immunoprecipitation. Immunopreciptation with an antibody that targets a transcription factor or histone modification allows for selection and enrichment of specific genomic regions for investigation of long-range chromosomal interactions.</obo:IAO_0000115>
<obo:IAO_0000117>Hector Guzman-Orozco</obo:IAO_0000117>
<obo:IAO_0000118>PLAC-seq</obo:IAO_0000118>
<obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143423/</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1145</obo:IAO_0000233>
<rdfs:label>proximity ligation-assisted ChIP-seq</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003553 -->
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<obo:IAO_0000111>intragastric administration</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An administration of a substance into the stomach of an organism.</obo:IAO_0000115>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1703</obo:IAO_0000233>
<rdfs:label>intragastric administration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003554 -->
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</owl:Restriction>
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<obo:IAO_0000111>intracolonic administration</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An administration of a substance into the colon of an organism.</obo:IAO_0000115>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1703</obo:IAO_0000233>
<rdfs:label>intracolonic administration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003555 -->
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</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>vaginal administration</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An administration of a substance into the vagina of an organism.</obo:IAO_0000115>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1703</obo:IAO_0000233>
<rdfs:label>vaginal administration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003556 -->
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<obo:IAO_0000111>topical administration</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An administration of a substance onto the surface of the skin of an organism.</obo:IAO_0000115>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000118>percutaneous administration</obo:IAO_0000118>
<obo:IAO_0000118>transcutaneous administration</obo:IAO_0000118>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1703</obo:IAO_0000233>
<rdfs:label>topical administration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003557 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003557">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600007"/>
<rdfs:subClassOf>
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</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
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<obo:IAO_0000111>cervical administration</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An administration of a substance to the cervix of an organism.</obo:IAO_0000115>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1703</obo:IAO_0000233>
<rdfs:label>cervical administration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003558 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003558">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600007"/>
<rdfs:subClassOf>
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</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
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<obo:IAO_0000111>conjunctival administration</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An administration of a substance to the conjunctiva of an organism.</obo:IAO_0000115>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1703</obo:IAO_0000233>
<rdfs:label>conjunctival administration</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003559 -->
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<rdfs:subClassOf>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0003126"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>intratracheal administration</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An administration of a substance into the trachea of an organism.</obo:IAO_0000115>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1703</obo:IAO_0000233>
<rdfs:label>intratracheal administration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003560 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003560">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600007"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000444"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000305"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>intra-amniotic administration</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An administration of a substance into the amnion of an organism.</obo:IAO_0000115>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1703</obo:IAO_0000233>
<rdfs:label>intra-amniotic administration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003561 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003561">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600007"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000444"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001637"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>intra-arterial administration</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An administration of a substance into the artery of an organism.</obo:IAO_0000115>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1703</obo:IAO_0000233>
<rdfs:label>intra-arterial administration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003562 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003562">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600007"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000444"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001893"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>intracerebral administration</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An administration of a substance into the cerebrum of an organism.</obo:IAO_0000115>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1703</obo:IAO_0000233>
<rdfs:label>intracerebral administration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003563 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003563">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600007"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000444"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0003128"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>intracranial administration</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An administration of a substance into the cranium of an organism.</obo:IAO_0000115>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1703</obo:IAO_0000233>
<rdfs:label>intracranial administration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003564 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003564">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600007"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000444"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001003"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>intraepidermal administration</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An administration of a substance into the epidermis of an organism.</obo:IAO_0000115>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1703</obo:IAO_0000233>
<rdfs:label>intraepidermal administration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003565 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003565">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600007"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000444"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002465"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>intralymphatic administration</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An administration of a substance into the lymphatic system of an organism.</obo:IAO_0000115>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1703</obo:IAO_0000233>
<rdfs:label>intralymphatic administration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003566 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003566">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003565"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000444"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000029"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>lymph node administration</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An intralymphatic administration in which the substance is administered into a lymph node.</obo:IAO_0000115>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1703</obo:IAO_0000233>
<rdfs:label>lymph node administration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003567 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003567">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600007"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000444"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000057"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>urethral administration</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An administration of a substance into the urethra of an organism.</obo:IAO_0000115>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1703</obo:IAO_0000233>
<rdfs:label>urethral administration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003568 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003568">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003564"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0003575"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000444"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001003"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>skin scarification administration</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An intraepidermal administration in which the skin is scratched before the substance is administered to the skin.</obo:IAO_0000115>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1703</obo:IAO_0000233>
<rdfs:label>skin scarification administration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003569 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003569">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600007"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000444"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000995"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>intrauteral administration</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An adminstration of a substance into the uterus of an organism.</obo:IAO_0000115>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1703</obo:IAO_0000233>
<rdfs:label>intrauteral administration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003570 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003570">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003561"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000444"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001530"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>intracarotid administration</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An intra-arterial administration in which the substance is administered into the carotid artery.</obo:IAO_0000115>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000118>i.c.</obo:IAO_0000118>
<obo:IAO_0000118>i.c. administration</obo:IAO_0000118>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1703</obo:IAO_0000233>
<rdfs:label>intracarotid administration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003571 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003571">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600007"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000444"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000970"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>intraocular administration</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An administration of a substance to the eye of an organism.</obo:IAO_0000115>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1703</obo:IAO_0000233>
<rdfs:label>intraocular administration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003572 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003572">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600007"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000444"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001987"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>intraplacental administration</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An administration of a substance into the placenta of an organism.</obo:IAO_0000115>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1703</obo:IAO_0000233>
<rdfs:label>intraplacental administration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003573 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003573">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600007"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000444"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001052"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>intrarectal administration</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An administration of a substance into the rectum of an organism.</obo:IAO_0000115>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1703</obo:IAO_0000233>
<rdfs:label>intrarectal administration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003574 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003574">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600007"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000444"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002106"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>intrasplenic administration</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An administration of a substance into the spleen of an organism.</obo:IAO_0000115>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1703</obo:IAO_0000233>
<rdfs:label>intrasplenic administration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003575 -->
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<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
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<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000118>abrading</obo:IAO_0000118>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1703</obo:IAO_0000233>
<rdfs:label xml:lang="en">scratching</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003576 -->
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<obo:IAO_0000111>skin of body microbiology assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An organism detection assay that detects microorganisms in a skin of body specimen.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins ORCID:0000-0001-6595-0902</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1680</obo:IAO_0000233>
<rdfs:label>skin of body microbiology assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003577 -->
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<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An organism detection datum that is the specified output of a skin of body microbiology assay.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins ORCID:0000-0001-6595-0902</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1680</obo:IAO_0000233>
<rdfs:label>skin of body microbiology datum</rdfs:label>
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<obo:IAO_0000111>bone marrow microbiology assay</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">An organism detection assay that detects microorganisms in a bone marrow specimen.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins ORCID:0000-0001-6595-0902</obo:IAO_0000117>
<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1680</obo:IAO_0000233>
<rdfs:label>bone marrow microbiology assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003579 -->
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<obo:IAO_0000115 xml:lang="en">An organism detection datum that is the specified output of a bone marrow microbiology assay.</obo:IAO_0000115>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1680</obo:IAO_0000233>
<rdfs:label>bone marrow microbiology datum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003580 -->
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<obo:IAO_0000111>nasal aspirate microbiology assay</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">An organism detection assay that detects microorganisms in a nasal aspirate specimen.</obo:IAO_0000115>
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<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1680</obo:IAO_0000233>
<rdfs:label>nasal aspirate microbiology assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003581 -->
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<obo:IAO_0000115 xml:lang="en">An organism detection datum that is the specified output of a nasal aspirate microbiology assay.</obo:IAO_0000115>
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<obo:IAO_0000119>VEuPathDB</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1680</obo:IAO_0000233>
<rdfs:label>nasal aspirate microbiology datum</rdfs:label>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1007</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_0003583 -->
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1007</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1007</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_0003586 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0302887"/>
<obo:IAO_0000111 xml:lang="en">Annexin V staining</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Staining using Annexin V to detect apoptotic cells.</obo:IAO_0000115>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1007</obo:IAO_0000233>
<rdfs:label xml:lang="en">Annexin V staining</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003587 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003587">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100060"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>cell culture assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An assay that has cell culture as an input.</obo:IAO_0000115>
<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<rdfs:label>cell culture assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003589 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003589">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002145"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100017"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100017"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0019814"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0001637"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10376"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0019814"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0001637"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10376"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002145"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<obo:IAO_0000111>serum anti-Epstein-Barr virus antibody level assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An antigen specific antibodies assay that is meant to detect antibodies that bind to Epstein-Barr virus (EBV) antigens in a serum sample.</obo:IAO_0000115>
<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000118>EBV</obo:IAO_0000118>
<rdfs:label>serum anti-Epstein-Barr virus antibody level assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003590 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003590">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002154"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100017"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100017"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002154"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<obo:IAO_0000111>serum anti-cytomegalovirus antibody level assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A CMV antibody assay that has serum as an input.</obo:IAO_0000115>
<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000118>CMV</obo:IAO_0000118>
<rdfs:label>serum anti-cytomegalovirus antibody level assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003591 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003591">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000123"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100051"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">chronic allograft damage index score</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A clinical data item that quantifies the degree of tissue damage in biopsies taken from transplanted kidneys.</obo:IAO_0000115>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000118>CADI</obo:IAO_0000118>
<rdfs:label xml:lang="en">chronic allograft damage index score</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003592 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003592">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000123"/>
<obo:IAO_0000111 xml:lang="en">sequential organ failure assessment score</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A clinical data item that quantifies the degree of function of a critically ill patient's organs.</obo:IAO_0000115>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000118>SOFA score</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/SOFA_score</obo:IAO_0000119>
<rdfs:label xml:lang="en">sequential organ failure assessment score</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003593 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003593">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000123"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000063"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">physician's global assessment of disease activity</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A clinical data item that quantifies a physician's judgement of the overall activity of some specific disease in a patient.</obo:IAO_0000115>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000118>MD global, PGA</obo:IAO_0000118>
<rdfs:label xml:lang="en">physician's global assessment of disease activity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003594 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003594">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001404"/>
<obo:IAO_0000111 xml:lang="en">human leukocyte antigen mismatch count</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A genetic characteristics information that is about the number of dissimilarities in the human leukocyte antigen gene complexes of two humans.</obo:IAO_0000115>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000118>HLA mismatch count, HLA mismatch</obo:IAO_0000118>
<rdfs:label xml:lang="en">human leukocyte antigen mismatch count</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003595 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003595">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003666"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600044"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000659"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001826"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003666"/>
<obo:IAO_0000111>nasal lavage fluid</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A specimen collected through nasal cavity lavage that contains the reagents used to for the lavage process, organisms, cells, cellular secretions, and other biomaterials present in the nasal cavity space.</obo:IAO_0000115>
<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<rdfs:label>nasal lavage fluid</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003598 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003598">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002991"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001010"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001010"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>single cell B cell receptor repertoire sequencing assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A B cell receptor repertoire sequencing assay that determines the sequence of DNA or RNA molecules that encode the repertoire of B cell receptors that can be traced to a single cell of origin.</obo:IAO_0000115>
<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000118>single-cell BCR assay</obo:IAO_0000118>
<rdfs:label>single cell B cell receptor repertoire sequencing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003599 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003599">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002990"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001010"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001010"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>single cell T cell receptor repertoire sequencing assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A T cell receptor repertoire sequencing assay that determines the sequence of DNA or RNA molecules that encode the repertoire of T cell receptors that can be traced to a single cell of origin.</obo:IAO_0000115>
<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000118>single-cell TCR assay</obo:IAO_0000118>
<rdfs:label>single cell T cell receptor repertoire sequencing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003600 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003600">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001930"/>
<obo:IAO_0000111>hypertension grade</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A categorical value specification that indicates the severity of hypertension.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<rdfs:label>hypertension grade</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003601 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003601">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>quartz crystal microbalance assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures the change in frequency of a quartz crystal resonator resulting from the addition or removal of a small mass of a ligand specifically binding at the surface of the resonator.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000118>QCM</obo:IAO_0000118>
<obo:IAO_0000119>http://www.ncbi.nlm.nih.gov/pubmed/23504432</obo:IAO_0000119>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Quartz_crystal_microbalance</obo:IAO_0000119>
<rdfs:label>quartz crystal microbalance assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003602 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003602">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001708"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003601"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001536"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001702"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000039"/>
<owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/UO_0000065"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>quartz crystal microbalance measuring the dissociation constant [KD] of a B cell epitope:antibody complex</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A quartz crystal microbalance assay that measures the dissociation constant [KD] of an antigen binding with an antibody.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000118>QCM measuring KD</obo:IAO_0000118>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>dissociation constant KD|quartz crystal microbalance|nM</obo:OBI_9991118>
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<!-- http://purl.obolibrary.org/obo/OBI_0003603 -->
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<!-- http://purl.obolibrary.org/obo/OBI_0003604 -->
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1724</obo:IAO_0000233>
<obo:IAO_0000234>Brain Image Library</obo:IAO_0000234>
<rdfs:label>multiplexed error-robust fluorescence in situ hybridization assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003605 -->
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<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
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<obo:IAO_0000119>https://doi.org/10.21769/BioProtoc.3070</obo:IAO_0000119>
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<obo:IAO_0000234>Brain Image Library</obo:IAO_0000234>
<rdfs:label>single molecule fluorescence in situ hybridization</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003606 -->
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<obo:IAO_0000111>Illumina NextSeq 1000</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A DNA sequencer which is manufactured by the Illumina corporation using sequence-by-synthesis chemistry that fits on a benchtop and uses P1 and P2 flow cells.</obo:IAO_0000115>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1711</obo:IAO_0000233>
<obo:IAO_0000234>GENEPIO</obo:IAO_0000234>
<rdfs:label>Illumina NextSeq 1000</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003607 -->
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<obo:IAO_0000115 xml:lang="en">An objective specification that is fulfilled by causing a disease in a particular organism.</obo:IAO_0000115>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<rdfs:label xml:lang="en">disease causation objective</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003608 -->
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<obo:IAO_0000115 xml:lang="en">An objective specification that is fulfilled by reducing the severity of a disease in a particular organism.</obo:IAO_0000115>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<rdfs:label xml:lang="en">disease severity reduction objective</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003609 -->
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<obo:IAO_0000115 xml:lang="en">An objective specification that is fulfilled by preventing the development of a disease in a particular organism.</obo:IAO_0000115>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<rdfs:label xml:lang="en">disease prevention objective</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003610 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003610">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<obo:IAO_0000111 xml:lang="en">reactant role</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A role borne by a biological or chemical entity that participates or has molecular components that participate in a chemical reaction.</obo:IAO_0000115>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<rdfs:label xml:lang="en">reactant role</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003611 -->
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<obo:IAO_0000115 xml:lang="en">A role borne by a biological or chemical entity which serves as the core component of a chemical reaction process, upon which other reactants, like reagents or solvents, act.</obo:IAO_0000115>
<obo:IAO_0000117>Cameron More</obo:IAO_0000117>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<rdfs:label xml:lang="en">precursor role</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003612 -->
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<!-- http://purl.obolibrary.org/obo/OBI_0003613 -->
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<!-- http://purl.obolibrary.org/obo/OBI_0003614 -->
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<!-- http://purl.obolibrary.org/obo/OBI_0003615 -->
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<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
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<!-- http://purl.obolibrary.org/obo/OBI_0003616 -->
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<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000119>Randi Vita</obo:IAO_0000119>
<rdfs:label>antibody purification of MHC class I protein complex</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0003617 -->
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<obo:IAO_0000115 xml:lang="en">An antibody purification of MHC class I protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of human MHC class I protein complex, while others contain impurities and are not of interest.</obo:IAO_0000115>
<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000119>Randi Vita</obo:IAO_0000119>
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<!-- http://purl.obolibrary.org/obo/OBI_0003618 -->
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<obo:IAO_0000115 xml:lang="en">An antibody purification of human MHC class I protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of HLA protein complex with A2 serotype, while others contain impurities and are not of interest.</obo:IAO_0000115>
<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
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<obo:IAO_0000119>Randi Vita</obo:IAO_0000119>
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<!-- http://purl.obolibrary.org/obo/OBI_0003619 -->
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<obo:IAO_0000115 xml:lang="en">An antibody purification of human MHC class I protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of HLA protein complex with A24 serotype, while others contain impurities and are not of interest.</obo:IAO_0000115>
<obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
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<!-- http://purl.obolibrary.org/obo/OBI_0003620 -->
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<!-- http://purl.obolibrary.org/obo/OBI_0003621 -->
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<!-- http://purl.obolibrary.org/obo/OBI_0003632 -->
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<!-- http://purl.obolibrary.org/obo/OBI_0003634 -->
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/494</obo:IAO_0000233>
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<obo:IAO_0000117>Anoosha Sehar https://orcid.org/0000-0001-5275-8866</obo:IAO_0000117>
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<obo:IAO_0000234>Philippe Rocca-Serra</obo:IAO_0000234>
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<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
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<obo:IAO_0000118>NovaSeq X System</obo:IAO_0000118>
<obo:IAO_0000119>https://emea.illumina.com/systems/sequencing-platforms/novaseq-x-plus.html</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1802</obo:IAO_0000233>
<obo:IAO_0000234>Morgana Barroso Oquendo</obo:IAO_0000234>
<rdfs:label>Illumina NovaSeq X Plus</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003666 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003666">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600044"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000953"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>lavage fluid specimen</obo:IAO_0000111>
<obo:IAO_0000112>The collection of bronchoalveolar lavage fluid (BAL) from the lungs of mice in order to study the cytokines present.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A specimen obtained through a lavage process which includes fluid in addition to cells and/or cellular secretions.</obo:IAO_0000115>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1803</obo:IAO_0000233>
<rdfs:label>lavage fluid specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003667 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003667">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003666"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600044"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000659"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000165"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003666"/>
<obo:IAO_0000111>oral lavage fluid</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A specimen collected through oral cavity lavage that contains the reagents used to for the lavage process, organisms, cells, cellular secretions, and other biomaterials present in the oral cavity space.</obo:IAO_0000115>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000118>mouth rinse specimen</obo:IAO_0000118>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1803</obo:IAO_0000233>
<obo:IAO_0000234>Anna Maria Masci</obo:IAO_0000234>
<rdfs:label>oral lavage fluid</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003683 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003683">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400103"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
<owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/OBI_0000759"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>Illumina HiSeq series instrument</obo:IAO_0000111>
<obo:IAO_0000112>https://www.illumina.com/content/dam/illumina-support/documents//products/datasheets/datasheet_hiseq_systems.pdf</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A DNA Sequencer manufactured and/or marketed by Illumina and branded with the word HiSeq.</obo:IAO_0000115>
<obo:IAO_0000116>This class represents a series of instruments with various model names. There are several models in this series, including one that was simply called “HiSeq” as the model name. GENEPIO:0100110 ‘Illumina HiSeq’ may refer to a model, not the series. OBI may not have classes for all of the instruments in this series.</obo:IAO_0000116>
<obo:IAO_0000117>PERSON: Mark Andrew Miller</obo:IAO_0000117>
<obo:IAO_0000118>HiSeq series</obo:IAO_0000118>
<obo:IAO_0000119>PERSON: Mark Andrew Miller</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1825</obo:IAO_0000233>
<obo:IAO_0000234>Alicia Clum</obo:IAO_0000234>
<rdfs:label>Illumina HiSeq series instrument</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003684 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003684">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400103"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
<owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/OBI_0000759"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>Illumina NextSeq series instrument</obo:IAO_0000111>
<obo:IAO_0000112>https://www.cd-genomics.com/blog/nextseq/</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A DNA Sequencer manufactured and/or marketed by Illumina and branded with the word NextSeq.</obo:IAO_0000115>
<obo:IAO_0000116>This class represents a series of instruments with various model names. There are several models in this series. OBI may not have classes for all of the instruments in this series. It is unclear whether GENEPIO:0100126 ’Illumina NextSeq’ refers to the series or a model.</obo:IAO_0000116>
<obo:IAO_0000117>PERSON: Mark Andrew Miller</obo:IAO_0000117>
<obo:IAO_0000118>NextSeq series</obo:IAO_0000118>
<obo:IAO_0000119>PERSON: Mark Andrew Miller</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1825</obo:IAO_0000233>
<obo:IAO_0000234>Alicia Clum</obo:IAO_0000234>
<rdfs:label>Illumina NextSeq series instrument</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003685 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003685">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400103"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
<owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/OBI_0000759"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>Illumina NovaSeq series instrument</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A DNA Sequencer manufactured and/or marketed by Illumina and branded with the word NovaSeq.</obo:IAO_0000115>
<obo:IAO_0000116>This class represents a series of instruments with various model names. There are several models in this series. OBI may not have classes for all of the instruments in this series. It is unclear whether GENEPIO:0100122 ‘Illumina NovaSeq’ refers to the series or to a model.</obo:IAO_0000116>
<obo:IAO_0000117>PERSON: Mark Andrew Miller</obo:IAO_0000117>
<obo:IAO_0000118>NovaSeq series</obo:IAO_0000118>
<obo:IAO_0000119>PERSON: Mark Andrew Miller</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1825</obo:IAO_0000233>
<obo:IAO_0000234>Alicia Clum</obo:IAO_0000234>
<rdfs:label>Illumina NovaSeq series instrument</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003686 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003686">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>chromatin accessibility assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that determines which regions of a DNA molecule are in the form of euchromatin and thus able to make direct physical contact with (i.e. are accessible to) other molecules such as RNA polymerase, transcription factors, etc.</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Michelle Giglio</obo:IAO_0000117>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000119>Michelle Giglio</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1813</obo:IAO_0000233>
<obo:IAO_0000234>Jennifer Jou</obo:IAO_0000234>
<rdfs:label>chromatin accessibility assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003687 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003687">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003686"/>
<obo:IAO_0000111>m6A-MTase sequencing assay</obo:IAO_0000111>
<obo:IAO_0000112>https://pubmed.ncbi.nlm.nih.gov/32587015/</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A DNA methylation profiling assay in which chromatin stencils are created by treating nuclei with m6A methyltransferase (MTase) and then sequenced using single-molecule circular consensus sequencing to identify regions of accessible DNA at nucleotide resolution.</obo:IAO_0000115>
<obo:IAO_0000117>Jennifer Jou</obo:IAO_0000117>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000118>Fiber-seq</obo:IAO_0000118>
<obo:IAO_0000119>Jennifer Jou</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1813</obo:IAO_0000233>
<obo:IAO_0000234>Jennifer Jou</obo:IAO_0000234>
<rdfs:label>m6A-MTase sequencing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003688 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003688">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400120"/>
<obo:IAO_0000111>sand bath</obo:IAO_0000111>
<obo:IAO_0000112>A sand bath was used to provide even heating of the round-bottom flask at elevated temperatures.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A temperature control bath in which sand acts as contact medium for the temperature transfer (from heating or cooling elements to the sample).</obo:IAO_0000115>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000117>https://orcid.org/0000-0002-8786-1756 (Schafer, Wes)</obo:IAO_0000117>
<obo:IAO_0000119>Based on OBI:0400157</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1585</obo:IAO_0000233>
<obo:IAO_0000234>https://orcid.org/0000-0002-8786-1756 (Schafer, Wes)</obo:IAO_0000234>
<rdfs:label>sand bath</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003689 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003689">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400120"/>
<obo:IAO_0000111>ice bath</obo:IAO_0000111>
<obo:IAO_0000112>A brine water ice bath was used to keep the reaction below 0 degrees Celsius.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A temperature control bath in which a water ice mixture acts as contact medium at constant temperature of 0 degrees Celsius or below if salt solutions are used.</obo:IAO_0000115>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000117>https://orcid.org/0000-0002-8786-1756 (Schafer, Wes)</obo:IAO_0000117>
<obo:IAO_0000119>Based on OBI:0400157</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1585</obo:IAO_0000233>
<obo:IAO_0000234>https://orcid.org/0000-0002-8786-1756 (Schafer, Wes)</obo:IAO_0000234>
<rdfs:label>ice bath</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003690 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003690">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400120"/>
<obo:IAO_0000111>dry ice bath</obo:IAO_0000111>
<obo:IAO_0000112>A dry ice bath using ethylene glycol was used to maintain a temperature of -10 degrees Celsius.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A temperature control bath in which a dry ice solvent mixture acts as contact medium at a constant temperatures significantly below 0 degrees Celsius.</obo:IAO_0000115>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000117>https://orcid.org/0000-0002-8786-1756 (Schafer, Wes)</obo:IAO_0000117>
<obo:IAO_0000119>Based on OBI:0400157</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1585</obo:IAO_0000233>
<obo:IAO_0000234>https://orcid.org/0000-0002-8786-1756 (Schafer, Wes)</obo:IAO_0000234>
<rdfs:label>dry ice bath</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0003691 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003691">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400120"/>
<obo:IAO_0000111>liquid nitrogen bath</obo:IAO_0000111>
<obo:IAO_0000112>A liquid nitrogen bath is used to adsorb helium gas on samples for surface area measurements.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A temperature control bath in which liquid nitrogen acts as contact medium providing a constant temperature of −195.8 °C at 1 atm.</obo:IAO_0000115>
<obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
<obo:IAO_0000117>https://orcid.org/0000-0002-8786-1756 (Schafer, Wes)</obo:IAO_0000117>
<obo:IAO_0000119>Based on OBI:0400157</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1585</obo:IAO_0000233>
<obo:IAO_0000234>https://orcid.org/0000-0002-8786-1756 (Schafer, Wes)</obo:IAO_0000234>
<rdfs:label>liquid nitrogen bath</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0005246 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0005246">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
<obo:IAO_0000111>injection function</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">The function of a device realized when administering a substance in vivo, applied particularly to the forcible insertion of a liquid or gas by means of a syringe, pump, etc.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000119>adapted from WEB: http://www.dictionary.net/injection</obo:IAO_0000119>
<rdfs:label>injection function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0100010 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0100010">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0600036"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10239"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000236"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<obo:IAO_0000111 xml:lang="en">Epstein Barr virus transformed B cell</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PMID: 8777380. Expression of thyroid peroxidase in EBV-transformed B cell lines using adenovirus.Thyroid. 1996 Feb;6(1):23-8.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A material entity which results from viral transformation process using EBV as transformation agent when applied to B-cell entity</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Susanna Sansone</obo:IAO_0000117>
<obo:IAO_0000119>GROUP: OBI Biomaterial Branch</obo:IAO_0000119>
<rdfs:label xml:lang="en">Epstein Barr virus transformed B cell</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0100014 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0100014">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
<obo:IAO_0000111 xml:lang="en">chimera</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An organism which contains cells or tissues with a different genotype</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON: Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">GROUP: OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">chimera</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0100015 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0100015">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_anatomical entity</obo:IAO_0000111>
<obo:IAO_0000112>Tissue, organ, system, sperm, blood or body location (arm).</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000121"/>
<obo:IAO_0000115 xml:lang="en">An anatomical entity is a material entity that is part of a multicellular organism, and which is large enough so that it forms an identifiable structure in the organism. Specifically, it excludes granular parts of the organism, such as atoms, molecules, cells, which can be removed from the organism without affecting it. It is defined as the union of 'multi-tissue structure', 'body substance' and 'portion of tissue'</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000117>Tina Boussard</obo:IAO_0000117>
<obo:IAO_0000119>MO</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<rdfs:label>obsolete_anatomical entity</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0100016 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0100016">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000655"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000953"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0600014"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000655"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>blood plasma specimen</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 18217225.Sex Transm Dis. 2008 Jan;35(1):55-60. Review.Human immunodeficiency virus viral load in blood plasma and semen: review and implications of empirical findings.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a material entity which corresponds to the liquid component of blood, in which the blood cells are suspended.</obo:IAO_0000115>
<obo:IAO_0000116>03/21/2010: BP, blood plasma is defined as the output of certain separation processes, so this is in the domain of OBI, not FMA.</obo:IAO_0000116>
<obo:IAO_0000117>PERSON: Maura Gasparetto</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>plasma</obo:IAO_0000118>
<obo:IAO_0000119>WEB: http://en.wikipedia.org/wiki/Blood_plasma</obo:IAO_0000119>
<rdfs:label>blood plasma specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0100017 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0100017">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0100016"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0302885"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0302886"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0600052"/>
</owl:unionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000655"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>blood serum specimen</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 18229666.Adv Med Sci. 2007;52 Suppl 1:204-6.Antioxidant activity of blood serum and saliva in patients with periodontal disease treated due to epilepsy.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A material entity which derives from blood and corresponds to blood plasma without fibrinogen or the other clotting factors.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Maura Gasparetto</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>WEB: http://en.wikipedia.org/wiki/Blood_plasma</obo:IAO_0000119>
<rdfs:label>blood serum specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0100026 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0100026">
<owl:equivalentClass>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10239"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2157"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2759"/>
</owl:unionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000111 xml:lang="en">organism</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">animal</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">fungus</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">plant</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">virus</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A material entity that is an individual living system, such as animal, plant, bacteria or virus, that is capable of replicating or reproducing, growth and maintenance in the right environment. An organism may be unicellular or made up, like humans, of many billions of cells divided into specialized tissues and organs.</obo:IAO_0000115>
<obo:IAO_0000116>10/21/09: This is a placeholder term, that should ideally be imported from the NCBI taxonomy, but the high level hierarchy there does not suit our needs (includes plasmids and 'other organisms')</obo:IAO_0000116>
<obo:IAO_0000116>13-02-2009:
OBI doesn't take position as to when an organism starts or ends being an organism - e.g. sperm, foetus.
This issue is outside the scope of OBI.</obo:IAO_0000116>
<obo:IAO_0000117>GROUP: OBI Biomaterial Branch</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">WEB: http://en.wikipedia.org/wiki/Organism</obo:IAO_0000119>
<rdfs:label xml:lang="en">organism</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0100035 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0100035">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_immortal cell</obo:IAO_0000111>
<obo:IAO_0000112>a single Hela cell</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a cell derived from a multicellular organism that has the potential to replicate indefinitely</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>GROUP: OBI Biomaterial Branch</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<rdfs:label>obsolete_immortal cell</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0100039 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0100039">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_fragment derived from protein</obo:IAO_0000111>
<obo:IAO_0000112>the peptide with sequence SIINFEKL, which is eluted from a cell expressing hen egg lysozyme</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A material entity which is derived from a protein</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>GROUP: IEDB</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_fragment derived from protein</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0100046 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0100046">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0302729"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000576"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_26710"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000576"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_37586"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0302731"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">phosphate buffered saline solution</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PMID: 16279733.Dent Mater J. 2005 Sep;24(3):414-21.PBS buffer solutions with different pH values can change porosity of DNA-chitosan complexes.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">Phosphate buffered saline (abbreviated PBS) is a buffer solution commonly used in biochemistry. It is a salty solution containing sodium chloride, sodium phosphate and in some preparations potassium chloride and potassium phosphate. The buffer helps to maintain a constant pH. The concentration usually matches the human body (isotonic).</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON: Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">PERSON: Tina Boussard</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">PBS buffer</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">WEB: http://en.wikipedia.org/wiki/Phosphate_buffered_saline</obo:IAO_0000119>
<rdfs:label xml:lang="en">phosphate buffered saline solution</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0100051 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0100051">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000112"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000111 xml:lang="en">specimen</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Biobanking of blood taken and stored in a freezer for potential future investigations stores specimen; collecting a stone from a site.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A material entity that is collected for potential use as an input upon which measurements or observations are performed.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: James Malone</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">GROUP: OBI Biomaterial Branch</obo:IAO_0000119>
<obo:IAO_0000233 rdf:resource="https://github.com/obi-ontology/obi/issues/1013"/>
<rdfs:label xml:lang="en">specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0100055 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0100055">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_cell line cell</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A material entity that represents generations of a primary culture.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Susanna Sansone</obo:IAO_0000117>
<obo:IAO_0000119>GROUP: OBI Biomaterial Branch</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<rdfs:label>obsolete_cell line cell</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0100056 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0100056">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_immortal cell line culture</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cell line that is expected to be capable of indefinite propagation in an vitro culture.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Matthew Brush</obo:IAO_0000117>
<obo:IAO_0000118>immortal cell line sample</obo:IAO_0000118>
<obo:IAO_0000118>permanent cell line</obo:IAO_0000118>
<obo:IAO_0000119>PERSON:Matthew Brush</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/CLO_0009828"/>
<rdfs:label>obsolete_immortal cell line culture</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0100058 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0100058">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000105"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">xenograft</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Human xenotransplantation (e.g. from pig to human) offers a potential treatment for end-stage organ failure, a significant health problem in parts of the industrialized world</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A material entity which results from the transplantation of living cells, tissues or organs from on organism of one species to an organism of another species.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON: Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">xenotransplant</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">WEB: http://en.wikipedia.org/wiki/Xenograft</obo:IAO_0000119>
<rdfs:label xml:lang="en">xenograft</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0100060 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0100060">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600024"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000010"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000010"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>cultured cell population</obo:IAO_0000111>
<obo:IAO_0000112>A cultured cell population applied in an experiment: "293 cells expressing TrkA were serum-starved for 18 hours and then neurotrophins were added for 10 min before cell harvest." (Lee, Ramee, et al. "Regulation of cell survival by secreted proneurotrophins." Science 294.5548 (2001): 1945-1948).
A cultured cell population maintained in vitro: "Rat cortical neurons from 15 day embryos are grown in dissociated cell culture and maintained in vitro for 8–12 weeks" (Dichter, Marc A. "Rat cortical neurons in cell culture: culture methods, cell morphology, electrophysiology, and synapse formation." Brain Research 149.2 (1978): 279-293).</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A processed material comprised of a collection of cultured cells that has been continuously maintained together in culture and shares a common propagation history.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">2013-6-5 MHB: This OBI class was formerly called 'cell culture', but label changed and definition updated following CLO alignment efforts in spring 2013, during which the intent of this class was clarified to refer to portions of a culture or line rather than a complete cell culture or line.</obo:IAO_0000116>
<obo:IAO_0000117>PERSON:Matthew Brush</obo:IAO_0000117>
<obo:IAO_0000118>cell culture sample</obo:IAO_0000118>
<obo:IAO_0000119>PERSON:Matthew Brush</obo:IAO_0000119>
<rdfs:comment>The extent of a 'cultured cell population' is restricted only in that all cell members must share a propagation history (ie be derived through a common lineage of passages from an initial culture). In being defined in this way, this class can be used to refer to the populations that researchers actually use in the practice of science - ie are the inputs to culturing, experimentation, and sharing. The cells in such populations will be a relatively uniform population as they have experienced similar selective pressures due to their continuous co-propagation. And this population will also have a single passage number, again owing to their common passaging history. Cultured cell populations represent only a collection of cells (ie do not include media, culture dishes, etc), and include populations of cultured unicellular organisms or cultured multicellular organism cells. They can exist under active culture, stored in a quiescent state for future use, or applied experimentally.</rdfs:comment>
<rdfs:label>cultured cell population</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0100061 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0100061">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0100060"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000001"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000001"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:qualifiedCardinality rdf:datatype="http://www.w3.org/2001/XMLSchema#nonNegativeInteger">0</owl:qualifiedCardinality>
<owl:onClass rdf:resource="http://purl.obolibrary.org/obo/OBI_0600037"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>primary cultured cell population</obo:IAO_0000111>
<obo:IAO_0000112>Spleen cells put directly into culture; Cold storage of biopsies from wild endangered native Chilean species in field conditions and subsequent isolation of primary culture cell lines. In Vitro Cell Dev Biol Anim. 2008 Jul 2. PMID: 18594934</obo:IAO_0000112>
<obo:IAO_0000112>cells that have been isolated from some organismal source, expanded in culture, but not undergone a complete passaging (ie are still in culture, or have been lifted from culture and frozen in aliquots for future use)</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cultured cell population comprised of cells expanded directly from living tissue prior to being passaged.</obo:IAO_0000115>
<obo:IAO_0000116>2013-6-5 MHB: This OBI class was formerly called 'primary cell culture', but label changed and definition updated following CLO alignment work. Previous definition: 'a primary cell culture is a cell culture where the cells derive from a fresh tissue source.'</obo:IAO_0000116>
<obo:IAO_0000116>consider if we really want to be so strict here . . . ie maybe we we say that they have not been output from an 'establishing cell line' process, but in some cases a passage or two may be allowed for a primary culture. the establishing of a line requires some procedss that attains a degree of homogeneity in the culture.</obo:IAO_0000116>
<obo:IAO_0000117>PERSON:Matthew Brush</obo:IAO_0000117>
<obo:IAO_0000118>primary cell culture</obo:IAO_0000118>
<obo:IAO_0000118>primary cell culture sample</obo:IAO_0000118>
<obo:IAO_0000119>PERSON:Matthew Brush</obo:IAO_0000119>
<rdfs:label xml:lang="en">primary cultured cell population</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0100062 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0100062">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_cell line</obo:IAO_0000111>
<obo:IAO_0000112>A split of HeLa cells in active culture, or stored in frozen aliquots. Populations of HEK 293 cells used in experiments such as those documented in Changes in ultrastructure and endogenous ionic channels activity during culture of HEK 293 cell line. Eur J Pharmacol. 2007 Jul 12;567(1-2):10-8. PMID: 17482592.</obo:IAO_0000112>
<obo:IAO_0000112>He, Tong-Chuan, et al. Identification of c-MYC as a target of the APC pathway. Science 281.5382 (1998): 1509-1512. - To evaluate the transcriptional effects of APC, we studied a human colorectal cancer cell line (HT29-APC) containing a zinc-inducible APC gene and a control cell line (HT29–β-Gal) containing an analogous inducible lacZ gene. Note that common usage in the literature is often of the form a human colorectal cancer cell line, as seen above. But such references to studies in a line refer to the fact that discrete populations of cells that are input into culturing or experiments, not an entire lineage of cells. It is these discrete populations that we refer to as 'cell lines'.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A secondary cultured cell population that represents a genetically stable and homogenous population of cultured cells that shares a common propagation history (ie has been successively passaged together in culture).</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Matthew Brush</obo:IAO_0000117>
<obo:IAO_0000118>cell line sample</obo:IAO_0000118>
<obo:IAO_0000119>OBI-CLO Alignment Working Group (Spring 2013)</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/CLO_0000031"/>
<rdfs:label>obsolete_cell line</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0100063 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0100063">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0100060"/>
<obo:IAO_0000111 xml:lang="en">cultured clonal cell population</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">cell cut
Stem cell functions assessed in clonal culture. Soc Gen Physiol Ser. 1988;43:39-45. Review. PMID: 3077557</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cultured cell population comprised of cells which can all be traced back to a single ancestor cell, and which therefore can be treated as identical.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Susanna Sansone</obo:IAO_0000117>
<obo:IAO_0000117>PERSON:Matthew Brush</obo:IAO_0000117>
<obo:IAO_0000118>clonal cell culture sample</obo:IAO_0000118>
<obo:IAO_0000119>GROUP: OBI Biomaterial Branch</obo:IAO_0000119>
<rdfs:label xml:lang="en">cultured clonal cell population</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0100064 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0100064">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<obo:IAO_0000111 xml:lang="en">screening library</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PMID: 15615535.J Med Chem. 2004 Dec 30;47(27):6864-74.A screening library for peptide activated G-protein coupled receptors. 1. The test set. [cdna_library, phage display library]</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a screening library is a collection of materials engineered to identify qualities of a subset of its members during a screening process?</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">PRS: 22-02-2008: while working on definition of cDNA library and looking at current example of usage, a screening library should be a defined class -> any material library which has input_role in a screening protocol application
change biomaterial to material in definition</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">PERSON: Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>GROUP: IEDB</obo:IAO_0000119>
<obo:IAO_0000232>7/13/09: Need to clarify if this meets reagent role definition</obo:IAO_0000232>
<rdfs:label xml:lang="en">screening library</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0100065 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0100065">
<owl:equivalentClass>
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</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16670"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<obo:IAO_0000111 xml:lang="en">synthetic peptide</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">the synthesized peptide SIINFEKL which also occurs in hen-egg lysozyme</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a synthetic peptide is an material entity which is artificially engineered and results from the synthesis of a chain of amino acids which may also be found in natural protein and be identical in sequence to a protein fragment</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">changed from synthetic polypeptide to peptide, to get rid of the restriction of having more than 10 amino acids (required by Chebi).</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">PRS:22-02-2008: a chebi entity which has output role in a synthesis protocol application</obo:IAO_0000232>
<obo:IAO_0000232 xml:lang="en">original term: protein fragment split into synthetic polypeptide and fragment derived from protein
DS: Is this synthetic an oxymoron to the biomaterial?</obo:IAO_0000232>
<rdfs:label xml:lang="en">synthetic peptide</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0100066 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0100066">
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</owl:unionOf>
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</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">organ section</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">A liver slice used in a perfusion experiment.
Thyroidectomy during laryngectomy for advanced laryngeal carcinoma--whole organ section study with long-term functional evaluation. Clin Otolaryngol Allied Sci. 1995 Apr;20(2):145-9. PMID: 7634521</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A processed material which derives from an organ and results from a process of dissection or histological sample preparation a portion(formerly an organ section is portion of an organ removed from the context of the organ)</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON: Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">GROUP: CEBS</obo:IAO_0000119>
<obo:IAO_0000119>GROUP: OBI Biomaterial Branch</obo:IAO_0000119>
<rdfs:label xml:lang="en">organ section</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0100067 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0100067">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003666"/>
<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
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</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002048"/>
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</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600044"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003666"/>
<obo:IAO_0000111>bronchial alveolar lavage</obo:IAO_0000111>
<obo:IAO_0000112>solution containing lung derived T cells, eosinophils, and TNFa.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Group of biomaterials present in the bronchial aveolar space of an organism which are collected through lavage including the reagents used to for the lavage process, organisms, cells, and cellular secretions present in the bronchial aveolar space.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000118>BAL</obo:IAO_0000118>
<obo:IAO_0000119>GROUP: IEDB</obo:IAO_0000119>
<rdfs:label>bronchial alveolar lavage</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0100069 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0100069">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_polymer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.</obo:IAO_0000115>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>TERM: CHEBI:33839</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<rdfs:label>obsolete_polymer</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0100086 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0100086">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17234"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>glucose in solution</obo:IAO_0000111>
<obo:IAO_0000112>Glucose present in blood</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A scattered aggregate of glucose molecules in a liquid</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Jie Zheng</obo:IAO_0000117>
<obo:IAO_0000118>glucose molecules</obo:IAO_0000118>
<rdfs:label>glucose in solution</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200000 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200000">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200166"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000059"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000064"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
</owl:Restriction>
</rdfs:subClassOf>
<owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/OBI_0600013"/>
<obo:IAO_0000111 xml:lang="en">data transformation</obo:IAO_0000111>
<obo:IAO_0000112>The application of a clustering protocol to microarray data or the application of a statistical testing method on a primary data set to determine a p-value.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A planned process that produces output data from input data.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Richard Scheuermann</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Ryan Brinkman</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Tina Hernandez-Boussard</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">data analysis</obo:IAO_0000118>
<obo:IAO_0000118 xml:lang="en">data processing</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">Branch editors</obo:IAO_0000119>
<rdfs:label xml:lang="en">data transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200001 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200001">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200181"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200184"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000674"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200177"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200078"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">geometric mean calculation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A data transformation in which the mean is calculated by taking the nth root of the product of all of the observations in a data (n being the number of all observations).</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Mathias Brochhausen</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Mathias Brochhausen</obo:IAO_0000119>
<rdfs:comment xml:lang="en">A geometric mean calculation is a descriptive statistics calculation in which the mean is calculated by taking the nth root of the product of all of the observations in a data (n being the number of all observations).</rdfs:comment>
<rdfs:label xml:lang="en">geometric mean calculation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200002 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200002">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200072"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200174"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">logistic-log curve fitting</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Typically used in an enzyme-linked immunosorbent assay (ELISA) to model the relationship between optical density (OD) and dilution. In this case a and d correspond to the theoretical OD of the assay at zero and infinite concentrations, respectively; c is the dilution associated with the point of symmetry of the sigmoid and is located at the midpoint of the assay found at the inflection point of the curve; b is a curvature parameter and is related to the slope of the curve.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A logistic-log curve fitting is a curve fitting where a curve of the form y=d+((a-d)/(1+(x/c)^b)) is obtained, where a, b, c, and d are determined so to optimize its fit to the input data points (x_1, y_1), (x_2, y_2), ..., (x_n, y_n).</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Ryan Brinkman</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">ARTICLE: Plikaytis B.D. et al. (1991), J. Clin. Microbiol. 29(7): 1439-1448</obo:IAO_0000119>
<rdfs:label xml:lang="en">logistic-log curve fitting</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200003 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200003">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200072"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200174"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">logit-log curve fitting</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Typically used in an enzyme-linked immunosorbent assay (ELISA) to model the relationship between optical density (OD) and dilution. In this case OD_0 (also referred to OD_min) and OD_infty (also referred to OD_max) correspond to the theoretical OD of the assay at zero and infinite concentrations, respectively.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A logit-log curve fitting is a curve fitting where first the limits y_0 an y_infty of y when x->0 and x->infinity, respectively, are estimated from the input data points (x_1, y_1), (x_2,y_2), ..., (x_n, y_n). Then a curve with equation log((y-y_0)/(y_infty-y))=a+b log(x) is obtained, where a and b are determined to optimize its fit to the input data points.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">The above definition refers to the 'fully specified' logit-log model. The reduced form of this, when it is assumed that y_0=0, is named 'partially specified' logit-log model.</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Ryan Brinkman</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">ARTICLE: Plikaytis B.D. et al. (1991), J. Clin. Microbiol. 29(7): 1439-1448</obo:IAO_0000119>
<rdfs:label xml:lang="en">logit-log curve fitting</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200004 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200004">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200072"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200174"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">log-log curve fitting</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Typically used in an enzyme-linked immunosorbent assay (ELISA) to model the relationship between optical density (OD) and dilution.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A log-log curve fitting is a curve fitting where first a logarithmic transformation is applied both to the x and the y coordinates of the input data points (x_1, y_1), (x_2, y_2), ..., (x_n, y_n), and then coefficients a and b are determined to optimize the fit of log(y)=a+b*log(x) to these input data points.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Ryan Brinkman</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">ARTICLE: Plikaytis B.D. et al. (1991), J. Clin. Microbiol. 29(7): 1439-1446</obo:IAO_0000119>
<rdfs:label xml:lang="en">log-log curve fitting</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200005 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200005">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200166"/>
<obo:IAO_0000111 xml:lang="en">feature extraction objective</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A feature extraction objective is a data transformation objective where the aim of the data transformation is to generate quantified values from a scanned image.</obo:IAO_0000115>
<obo:IAO_0000117>Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">TERM: http://mged.sourceforge.net/ontologies/MGEDOntology.owl#feature_extraction</obo:IAO_0000119>
<rdfs:label xml:lang="en">feature extraction objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200006 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200006">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200072"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200169"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000451"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200167"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200174"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">biexponential transformation</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">This type of transformation is typically used in flow cytometry.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A biexponential transformation is a data transformation that, for each (one dimensional) real number input x, outputs an approximation (found, e.g. with the Newton's method) to a solution y of the equation B(y)-x=0, where B denotes a b transformation.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Joseph Spliden</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Ryan Brinkman</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">WEB: http://flowcyt.sourceforge.net/gating/latest.pdf</obo:IAO_0000119>
<rdfs:label xml:lang="en">biexponential transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200007 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200007">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200169"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200167"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">box-cox transformation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A box-cox transformation is a data transformation according to the methods of Box and Cox as described in the article Box, G. E. P. and Cox, D.R. (1964) An analysis of transformations. Journal of Royal Statistical Society, Series B, vol. 26, pp. 211-246.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Ryan Brinkman</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">ARTICLE: Box, G. E. P. and Cox, D.R. (1964), "An analysis of transformations", Journal of Royal Statistical Society, Series B, vol. 26, pp. 211-246.</obo:IAO_0000119>
<rdfs:label xml:lang="en">box-cox transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200008 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200008">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200169"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200167"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">hyperlog transformation</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">This type of transformation is typically used in flow cytometry</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A hyperlog transformation ia a data transformation that, for each (one dimensional) real number input x, outputs an approximation (found, e.g. with the Newton's method) to a solution y of the equation EH(y)-x=0, where EH denotes an eh transformation.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Joseph Spliden</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Ryan Brinkman</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">ARTICLE: Bagwell C.B. (2006), "Hyperlog - a flexible log-like transform for negative, zero, and positive valued data", Cytometry A 64, 34-42."</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">http://flowcyt.sourceforge.net/gating/latest.pdf</obo:IAO_0000119>
<rdfs:label xml:lang="en">hyperlog transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200010 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200010">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200025"/>
<obo:IAO_0000111 xml:lang="en">loess scale group transformation one-channel</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Loess scale group normalization applied to data from two one-channel expression microarray assays.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A loess scale group transformation one-channel is a loess scale group transformation consisting in the application of a scale adjustment following a loess group transformation one-channel, to render the M group variances similar.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OTHER: Editor's adjustment based on MGED Ontology term</obo:IAO_0000119>
<rdfs:label xml:lang="en">loess scale group transformation one-channel</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200011 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200011">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200169"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200167"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">logical transformation</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">This type of transformation is typically used in flow cytometry.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A logical transformation is a data transformation that, for each (one dimensional) real number input x, outputs an approximation (found, e.g. with the Newton's method) to a solution y of the equation S(y)-x=0, where S denotes an s transformation.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Joseph Spliden</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Ryan Brinkman</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">WEB: http://flowcyt.sourceforge.net/gating/latest.pdf</obo:IAO_0000119>
<rdfs:label xml:lang="en">logical transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200012 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200012">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200025"/>
<obo:IAO_0000111 xml:lang="en">loess scale group transformation two-channel</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Loess scale group normalization applied to data from a two-channel expression microarray assay.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A loess scale group transformation two-channel is a loess scale group transformation consisting in the application of a scale adjustment following a loess group transformation two-channel, to render the M group variances similar.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OTHER: Adjusted from MGED Ontology</obo:IAO_0000119>
<rdfs:label xml:lang="en">loess scale group transformation two-channel</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200013 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200013">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200023"/>
<obo:IAO_0000111 xml:lang="en">loess global transformation one-channel</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Loess global normalization applied to data from two one-channel expression microarray assays, where the curve is obtained using all reporters. The goal is to remove intensity-dependent biases.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A loess global transformation one-channel is a loess global transformation in the special case where the input is the result of an MA transformation applied to intensities from two related one-channel assays.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OTHER: Editor's generalization based on MGED Ontology term</obo:IAO_0000119>
<rdfs:label xml:lang="en">loess global transformation one-channel</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200014 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200014">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200000"/>
<obo:IAO_0000111 xml:lang="en">split-scale transformation</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">This type of transformation is typically used in flow cytometry</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A split-scale transformation is a data transformation which is an application of a function f described as follows to a (one dimensional) real number input. f(x)=a*x+b if x=for x>t; where log denotes a logarithmic transformation and a, b, c, d, r, t are real constants, with a, c, d, r, t positive, chosen so that f is continuous with a continuous derivative at the transition point t.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Joseph Spliden</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Ryan Brinkman</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">WEB: http://flowcyt.sourceforge.net/gating/latest.pdf</obo:IAO_0000119>
<rdfs:label xml:lang="en">split-scale transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200015 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200015">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200023"/>
<obo:IAO_0000111 xml:lang="en">loess global transformation two-channel</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Loess global normalization applied to data from a two-channel expression microarray assay, where the curve is obtained using all reporters. The goal is to remove intensity-dependent biases.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A loess global transformation two-channel is a loess global transformation in the special case where the input the result of an MA transformation applied to intensities from the two channels of a two-channel assay.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OTHER: Editor's generalization based on MGED Ontology term</obo:IAO_0000119>
<rdfs:label xml:lang="en">loess global transformation two-channel</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200016 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200016">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200169"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200167"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">sine transformation</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">sine(0)=0, sine(pi/2)=1, sine(pi)=0, sine(3*pi/2)=-1, sine(pi/6)=1/2, sine(x+2*k*pi)=sine(x) where k is any integer, etc.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A sine transformation is a data transformation which consists in applying the sine function to a (one dimensional) real number input. The sine function is one of the basic trigonometric functions and a definition is provided, e.g., at http://mathworld.wolfram.com/Sine.html.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">WEB: http://mathworld.wolfram.com/Sine.html</obo:IAO_0000119>
<rdfs:label xml:lang="en">sine transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200017 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200017">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200169"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200167"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">cosine transformation</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">cosine(0)=1, cosine(pi/2)=0, cosine(pi)=-1, cosine(3*pi/2)=0, cosine(pi/3)=1/2, cosine(x+2*k*pi)=cosine(x) where k is any integer, etc.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A cosine transformation is a data transformation which consists in applying the cosine function to a (one dimensional) real number input. The cosine function is one of the basic trigonometric functions and a definition is provided, e.g., at http://mathworld.wolfram.com/Cosine.html.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">WEB: http://mathworld.wolfram.com/Cosine.html</obo:IAO_0000119>
<rdfs:label xml:lang="en">cosine transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200018 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200018">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200024"/>
<obo:IAO_0000111 xml:lang="en">loess group transformation one-channel</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">A loess group transformation one-channel is a loess group transformation in the special case where the input is the result of an MA transformation applied to intensities from two related one-channel assays.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A loess group transformation one-channel is a loess group transformation in the special case where the input is the result of an MA transformation applied to intensities from two related one-channel assays.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OTHER: Editor's generalization based on MGED Ontology term</obo:IAO_0000119>
<rdfs:label xml:lang="en">loess group transformation one-channel</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200019 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200019">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200024"/>
<obo:IAO_0000111 xml:lang="en">loess group transformation two-channel</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">A loess group transformation two-channel is a loess group transformation in the special case where the input is the result of an MA transformation applied to intensities from the two channels of a two-channel assay.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A loess group transformation two-channel is a loess group transformation in the special case where the input is the result of an MA transformation applied to intensities from the two channels of a two-channel assay.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OTHER: Editor's generalization based on MGED Ontology term</obo:IAO_0000119>
<rdfs:label xml:lang="en">loess group transformation two-channel</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200020 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200020">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200093"/>
<obo:IAO_0000111 xml:lang="en">homogeneous polynomial transformation</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">a*x, with a non-zero, is a homogeneous polynomial of degree 1 in 1 variable, a*x^2, with a non-zero, is a homogeneous polynomial of degree 2 in 1 variable; a_1*x_1+...+a_n*x_n, with at least one of the a_i's non-zero, is a homogeneous polynomial of degree one in n variables; a*x_n^3+b*x_1*x_2*x_3, with at least one of a and b non-zero, is a homogeneous polynomial of degree 3 in n variables.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A homogeneous polynomial transformation is a polynomial transformation where all the term of the polynomial have the same degree.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">WEB: http://mathworld.wolfram.com/HomogeneousPolynomial.html</obo:IAO_0000119>
<rdfs:label xml:lang="en">homogeneous polynomial transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200021 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200021">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200169"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200167"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">linlog transformation</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">This can be used for microarray normalization, e.g. to normalize the data from a two-channel expression microarray assay, as described in PMID 16646782.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A linlog transformation is a data transformation, described in PMID 16646782, whose input is a matrix [y_ik] and whose output is a matrix obtained by applying formula (9) of this paper, where values below an appropriately determined threshold (dependent on the row i) are transformed via a polynomial of degree 1, and values above this threshold are transformed via a logarithm.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PMID: 16646782</obo:IAO_0000119>
<rdfs:label xml:lang="en">linlog transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200022 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200022">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200169"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200167"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">variance stabilizing transformation</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">This can be used for expression microarray assay normalization and it is referred to as "variance stabilizing normalization", according to the procedure described e.g. in PMID 12169536.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A variance stabilizing transformation is a data transformation, described in PMID 12169536, whose input is a matrix [y_ik] and whose output is a matrix obtained by applying formula (6) in this paper. One of the goals is to obtain an output matrix whose rows have equal variances. The method relies on various assumptions described in the paper.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">variance stabilising transformation</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">PMID: 12169536</obo:IAO_0000119>
<rdfs:label xml:lang="en">variance stabilizing transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200023 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200023">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200071"/>
<obo:IAO_0000111 xml:lang="en">loess global transformation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A loess global transformation is a loess transformation where only one loess fitting is performed, utilizing one subset of (or possibly all of) the data points in the input so that there is only one resulting loess curve y=f(x) which is used for the transformation.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OTHER: Editor's generalization based on MGED Ontology term</obo:IAO_0000119>
<rdfs:label xml:lang="en">loess global transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200024 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200024">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200071"/>
<obo:IAO_0000111 xml:lang="en">loess group transformation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A loess group transformation is a loess transformation where the input is partitioned into groups and for each group a loess fitting is performed, utilizing a subset of (or possibly all of) the data points in that group. Thus, a collection of loess curves y=f_i(x) is generated, one per group. Each (x, y) in the input is transformed into (x, y-f_i(x)), where f_i(x) is the curve corresponding to the group to which that data point belongs.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OTHER: Editor's generalization based on MGED Ontology term</obo:IAO_0000119>
<rdfs:label xml:lang="en">loess group transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200025 -->
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<obo:IAO_0000111 xml:lang="en">loess scale group transformation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A loess scale group transformation is a data transformation consisting in the application of a scale adjustment following a loess group transformation, to render the group variances for the second variable (y) similar. Has objective scaling.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OTHER: Editor's generalization based on MGED Ontology term</obo:IAO_0000119>
<rdfs:label xml:lang="en">loess scale group transformation</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_0200026 -->
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<obo:IAO_0000111 xml:lang="en">total intensity transformation single</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">This can be used as a simple normalization method for expression microarray assays. For example, each intensity from a one-channel microarray assay is multiplied by a constant so that the output mean intensity over the microarray equals a desired target T (the multiplicative constant in this case is the T/(mean intensity)).</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A total intensity transformation single is a data transformation that takes as input an n-dimensional (real) vector and multiplies each component of this vector by a coefficient, where the coefficient is obtained by taking the sum of the input components or of a subset of these, multiplied by a constant of choice.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OTHER: Adjusted from MGED Ontology</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">Note that if the word "sum" is replaced by the word "mean" in the definition, the resulting definition is equivalent.</obo:IAO_0000232>
<rdfs:label xml:lang="en">total intensity transformation single</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200027 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200027">
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<obo:IAO_0000111 xml:lang="en">total intensity transformation paired</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">This can be used as a simple normalization method for the two channels from a two-channel expression microarray assay or from two related one-channel expression microarray assays.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A total intensity transformation paired is a data transformation that takes as input two n-dimensional (real) vectors and multiplies each component of the first vector by a coefficient, where the coefficient is obtained by taking the ratio of the sum of the second input components or of a subset of these by the sum of the first input components or of a subset of these (the same subset is used for the two vectors).</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OTHER: Adjusted from MGED Ontology</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">Note that if the word "sum" is replaced by the word "mean" in the definition, the resulting definition is equivalent.</obo:IAO_0000232>
<rdfs:label xml:lang="en">total intensity transformation paired</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200028 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200028">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200169"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200177"/>
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<obo:IAO_0000111 xml:lang="en">quantile transformation</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">This can be used for expression microarray assay normalization and it is referred to as "quantile normalization", according to the procedure described e.g. in PMID 12538238.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A quantile transformation is a data transformation that takes as input a collection of data sets, where each can be thought as an n-dimensional (real) vector, and which transforms each data set so that the resulting output data sets have equal quantiles.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Elisabetta Manduchi</obo:IAO_0000119>
<rdfs:label xml:lang="en">quantile transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200029 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200029">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200169"/>
<rdfs:subClassOf>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
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</owl:Restriction>
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<obo:IAO_0000111 xml:lang="en">mean centering</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">This can be used as a normalization method in expression microarray assays. For example, given a two-channel microarray assay, the log ratios of the two channels (M values) can be mean-centered.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A mean centering is a data transformation that takes as input an n-dimensional (real) vector, performs a mean calculation on its components, and subtracts the resulting mean from each component of the input.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">mean centring</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">PERSON: Elisabetta Manduchi</obo:IAO_0000119>
<rdfs:label xml:lang="en">mean centering</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200030 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200030">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200169"/>
<rdfs:subClassOf>
<owl:Restriction>
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</owl:Restriction>
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<obo:IAO_0000111 xml:lang="en">median centering</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">This can be used as a normalization method in expression microarray assays. For example, given a two-channel microarray assay, the log ratios of the two channels (M values) can be median-centered.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A median centering is a data transformation that takes as input an n-dimensional (real) vector, performs a median calculation on its components, and subtracts the resulting median from each component of the input.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">median centring</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">PERSON: Elisabetta Manduchi</obo:IAO_0000119>
<rdfs:label xml:lang="en">median centering</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200031 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200031">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200166"/>
<obo:IAO_0000111 xml:lang="en">differential expression analysis objective</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Analyses implemented by the SAM (http://www-stat.stanford.edu/~tibs/SAM), PaGE (www.cbil.upenn.edu/PaGE) or GSEA (www.broad.mit.edu/gsea/) algorithms and software</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A differential expression analysis objective is a data transformation objective whose input consists of expression levels of entities (such as transcripts or proteins), or of sets of such expression levels, under two or more conditions and whose output reflects which of these are likely to have different expression across such conditions.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Elisabetta Manduchi</obo:IAO_0000119>
<rdfs:label xml:lang="en">differential expression analysis objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200032 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200032">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000792"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
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</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">K-fold cross validation method</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">K-fold cross-validation randomly partitions the original sample into K subsamples. Of the K subsamples, a single subsample is retained as the validation data for testing the model, and the remaining K - 1 subsamples are used as training data. The cross-validation process is then repeated K times (the folds), with each of the K subsamples used exactly once as the validation data. The K results from the folds then can be averaged (or otherwise combined) to produce a single estimation. The advantage of this method over repeated random sub-sampling is that all observations are used for both training and validation, and each observation is used for validation exactly once. 10-fold cross-validation is commonly used</obo:IAO_0000115>
<obo:IAO_0000117>Person:Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000119>Tina Boussard</obo:IAO_0000119>
<rdfs:label xml:lang="en">K-fold cross validation method</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200033 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200033">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000792"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
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</owl:Restriction>
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<obo:IAO_0000111 xml:lang="en">leave one out cross validation method</obo:IAO_0000111>
<obo:IAO_0000112>The authors conducted leave-one-out cross validation to estimate the strength and accuracy of the differentially expressed filtered genes. http://bioinformatics.oxfordjournals.org/cgi/content/abstract/19/3/368</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">is a data transformation : leave-one-out cross-validation (LOOCV) involves using a single observation from the original sample as the validation data, and the remaining observations as the training data. This is repeated such that each observation in the sample is used once as the validation data</obo:IAO_0000115>
<obo:IAO_0000116>2009-11-10. Tracker: https://sourceforge.net/tracker/?func=detail&aid=2893049&group_id=177891&atid=886178</obo:IAO_0000116>
<obo:IAO_0000117>Person:Helen Parkinson</obo:IAO_0000117>
<rdfs:label xml:lang="en">leave one out cross validation method</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200034 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200034">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000792"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200188"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>jackknifing method</obo:IAO_0000111>
<obo:IAO_0000112>simple weighting procedure is suggested for combining information over alleles and loci, and sample variances may be estimated by a jackknife procedure</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Jacknifing is a re-sampling data transformation process used to estimate the precision of sampling statistics and is a resampling method</obo:IAO_0000115>
<obo:IAO_0000117>Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">jackknifing</obo:IAO_0000118>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Resampling_%28statistics%29</obo:IAO_0000119>
<rdfs:label xml:lang="en">jackknifing method</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200035 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200035">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000792"/>
<rdfs:subClassOf>
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</owl:Restriction>
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<obo:IAO_0000111 xml:lang="en">boostrapping</obo:IAO_0000111>
<obo:IAO_0000112>Although widely accepted that high throughput biological data are typically highly noisy, the effects that this uncertainty has upon the conclusions we draw from these data are often overlooked. However, in order to assign any degree of confidence to our conclusions, we must quantify these effects. Bootstrap resampling is one method by which this may be achieved.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Bootstrapping is a statistical method for estimating the sampling distribution of a statistic by sampling with replacement from the original data, most often with the purpose of deriving robust estimates of standard errors and confidence intervals of a population parameter like a mean, median, proportion, odds ratio, correlation coefficient or regression coefficient</obo:IAO_0000115>
<obo:IAO_0000117>Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000119>Bootstrapping is a data transformation process which estimates the precision of sampling statistics by drawing randomly with replacement from a set of data points</obo:IAO_0000119>
<rdfs:label xml:lang="en">boostrapping</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200036 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200036">
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000175"/>
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<rdfs:subClassOf>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000662"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001442"/>
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</owl:Restriction>
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<obo:IAO_0000111 xml:lang="en">Benjamini and Hochberg false discovery rate correction method</obo:IAO_0000111>
<obo:IAO_0000112>Statistical significance of the 8 most represented biological processes (GO level 4) among E7 6 month upregulated genes following analysis with DAVID software; Benjamini-Hochberg FDR (false discovery rate)</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A data transformation process in which the Benjamini and Hochberg method sequential p-value procedure is applied with the aim of correcting false discovery rate</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">2011-03-31: [PRS].
specified input and output of dt which were missing</obo:IAO_0000116>
<obo:IAO_0000117>Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>Helen Parkinson</obo:IAO_0000119>
<rdfs:label xml:lang="en">Benjamini and Hochberg false discovery rate correction method</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200037 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200037">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200169"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200167"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">pareto scaling</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A pareto scaling is a data transformation that divides all measurements of a variable by the square root of the standard deviation of that variable.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PMID:16762068</obo:IAO_0000119>
<rdfs:label xml:lang="en">pareto scaling</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200040 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200040">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200080"/>
<obo:IAO_0000111 xml:lang="en">modular decomposition</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Molecular decomposition is the partition of a network into distinct subgraphs for the purpose of identifying functional clusters. The network data is run through any of several existing algorithms designed to partition a network into distinct subgraphs for the purpose of isolating groups of functionally linked biological elements such as proteins.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Tina Hernandez-Boussard</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">editor</obo:IAO_0000119>
<rdfs:label xml:lang="en">modular decomposition</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200041 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200041">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200171"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200175"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000648"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200178"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200172"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">k-means clustering</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A k-means clustering is a data transformation which achieves a class discovery or partitioning objective, which takes as input a collection of objects (represented as points in multidimensional space) and which partitions them into a specified number k of clusters. The algorithm attempts to find the centers of natural clusters in the data. The most common form of the algorithm starts by partitioning the input points into k initial sets, either at random or using some heuristic data. It then calculates the mean point, or centroid, of each set. It constructs a new partition by associating each point with the closest centroid. Then the centroids are recalculated for the new clusters, and the algorithm repeated by alternate applications of these two steps until convergence, which is obtained when the points no longer switch clusters (or alternatively centroids are no longer changed).</obo:IAO_0000115>
<obo:IAO_0000117>Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">WEB: http://en.wikipedia.org/wiki/K-means</obo:IAO_0000119>
<rdfs:label xml:lang="en">k-means clustering</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200042 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200042">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200175"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000648"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200178"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">hierarchical clustering</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A hierarchical clustering is a data transformation which achieves a class discovery objective, which takes as input data item and builds a hierarchy of clusters. The traditional representation of this hierarchy is a tree (visualized by a dendrogram), with the individual input objects at one end (leaves) and a single cluster containing every object at the other (root).</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">WEB: http://en.wikipedia.org/wiki/Data_clustering#Hierarchical_clustering</obo:IAO_0000119>
<rdfs:label xml:lang="en">hierarchical clustering</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200043 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200043">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200154"/>
<obo:IAO_0000111 xml:lang="en">average linkage hierarchical clustering</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">An average linkage hierarchical clustering is an agglomerative hierarchical clustering which generates successive clusters based on a distance measure, where the distance between two clusters is calculated as the average distance between objects from the first cluster and objects from the second cluster.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Elisabetta Manduchi</obo:IAO_0000119>
<rdfs:label xml:lang="en">average linkage hierarchical clustering</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200044 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200044">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200154"/>
<obo:IAO_0000111 xml:lang="en">complete linkage hierarchical clustering</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">an agglomerative hierarchical clustering which generates successive clusters based on a distance measure, where the distance between two clusters is calculated as the maximum distance between objects from the first cluster and objects from the second cluster.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Elisabetta Manduchi</obo:IAO_0000119>
<rdfs:label xml:lang="en">complete linkage hierarchical clustering</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200045 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200045">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200154"/>
<obo:IAO_0000111 xml:lang="en">single linkage hierarchical clustering</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A single linkage hierarchical clustering is an agglomerative hierarchical clustering which generates successive clusters based on a distance measure, where the distance between two clusters is calculated as the minimum distance between objects from the first cluster and objects from the second cluster.</obo:IAO_0000115>
<obo:IAO_0000117>Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Elisabetta Manduchi</obo:IAO_0000119>
<rdfs:label xml:lang="en">single linkage hierarchical clustering</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200049 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200049">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200163"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000175"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000662"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001442"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000791"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">Benjamini and Yekutieli false discovery rate correction method</obo:IAO_0000111>
<obo:IAO_0000112>The expression set was compared univariately between the stroke patients and controls, gene list was generated using False Discovery Rate correction (Benjamini and Yekutieli)</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A data transformation in which the Benjamini and Yekutieli method is applied with the aim of correcting false discovery rate</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">2011-03-31: [PRS].
specified input and output of dt which were missing</obo:IAO_0000116>
<obo:IAO_0000117>Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>Helen Parkinson</obo:IAO_0000119>
<rdfs:label xml:lang="en">Benjamini and Yekutieli false discovery rate correction method</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200050 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200050">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200175"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000648"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200178"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">dimensionality reduction</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A dimensionality reduction is data partitioning which transforms each input m-dimensional vector (x_1, x_2, ..., x_m) into an output n-dimensional vector (y_1, y_2, ..., y_n), where n is smaller than m.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>data projection</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">PERSON: Elisabetta Manduchi</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">PERSON: James Malone</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">PERSON: Melanie Courtot</obo:IAO_0000119>
<rdfs:label xml:lang="en">dimensionality reduction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200051 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200051">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200050"/>
<obo:IAO_0000111 xml:lang="en">principal components analysis dimensionality reduction</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A principal components analysis dimensionality reduction is a dimensionality reduction achieved by applying principal components analysis and by keeping low-order principal components and excluding higher-order ones.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">pca data reduction</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">PERSON: Elisabetta Manduchi</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">PERSON: James Malone</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">PERSON: Melanie Courtot</obo:IAO_0000119>
<rdfs:label xml:lang="en">principal components analysis dimensionality reduction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200052 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200052">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200000"/>
<obo:IAO_0000111 xml:lang="en">probabilistic algorithm</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A probabilistic algorithm is one which involves an element of probability or randomness in the transformation of the data.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: James Malone</obo:IAO_0000119>
<rdfs:label xml:lang="en">probabilistic algorithm</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200053 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200053">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200052"/>
<obo:IAO_0000111 xml:lang="en">expectation maximization</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">EM is a probabilistic algorithm used to estimate the maximum likelihood of parameters from existing data where the model involves unobserved latent variables. The input to this method is the data model for which the estimation is performed over and the output is an approximated probability function.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: James Malone</obo:IAO_0000119>
<rdfs:label xml:lang="en">expectation maximization</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200054 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200054">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200147"/>
<obo:IAO_0000111 xml:lang="en">global modularity calculation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A network graph quality calculation in which an input data set of subgraph modules and their in-degree and out-degree qualities is used to calculate the average modularity of subgraphs within the network.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Richard Scheuermann</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Richard Scheuermann</obo:IAO_0000119>
<rdfs:label xml:lang="en">global modularity calculation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200055 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200055">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200057"/>
<obo:IAO_0000111 xml:lang="en">dye swap merge</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A dye swap merge is a replicate analysis which takes as input data from paired two-channel microarray assays where the sample labeled with one dye in the first assay is labeled with the other dye in the second assay and vice versa. The output for each reporter is obtained by combining its (raw or possibly pre-processed) M values in the two assays, where the M value in an assay is defined as the difference of the log intensities in the two channels. This can be used as a normalization step, when appropriate assumptions are met.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Elisabetta Manduchi</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">PERSON: James Malone</obo:IAO_0000119>
<rdfs:label xml:lang="en">dye swap merge</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200056 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200056">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200170"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000679"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000425"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">moving average</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">The moving average is often used to handle data from tiling arrays.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A moving average is a data transformation in which center calculations, usually mean calculations, are performed on values within a sliding window across the input data set.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Elisabetta Manduchi</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">PERSON: Helen Parkinson</obo:IAO_0000119>
<rdfs:label xml:lang="en">moving average</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200057 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200057">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200169"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200167"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">replicate analysis</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Replicate analysis can be used in microarray analysis to identify and potentially exclude low quality data.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A replicate analysis is a data transformation in which data from replicates are combined, e.g. through descriptive statistics calculations, and the results might be utilized for a variety of purposes, like assessing reproducibility, identifying outliers, normalizing, etc.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Helen Parkinson</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">PERSON:Elisabetta Manduchi</obo:IAO_0000119>
<rdfs:label xml:lang="en">replicate analysis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200058 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200058">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200187"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200081"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">b cell epitope prediction</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A B cell epitope prediction takes as input an antigen sequence, and through an analysis of this sequence, produces as output a prediction of the likelihood the biomaterial is a B Cell Epitope.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Helen Parkinson</obo:IAO_0000119>
<rdfs:label xml:lang="en">b cell epitope prediction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200059 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200059">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200187"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200081"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">mhc binding prediction</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An MHC binding prediction takes an input of a biomaterial sequence and through an analysis of this sequence, produces as output a prediction of the likelihood that the biomaterial will bind to an MHC molecule.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Helen Parkinson</obo:IAO_0000119>
<rdfs:label xml:lang="en">mhc binding prediction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200060 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200060">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200187"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200081"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">t cell epitope prediction</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A T cell epitope prediction takes as input an antigen sequence, and through an analysis of this sequence, produces as output a prediction of the likelihood the biomaterial is a T cell epitope.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Helen Parkinson</obo:IAO_0000119>
<rdfs:label xml:lang="en">t cell epitope prediction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200061 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200061">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200000"/>
<obo:IAO_0000111 xml:lang="en">data imputation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">Imputation is a means of filling in missing data values from a predictive distribution of the missing values. The predictive distribution can be created either based on a formal statistical model (i,e, a multivariate normal distribution) or an algorithm.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Monnie McGee</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">ARTICLE: Little, RJA and Rubin, DB (2002). Statistical Analysis with Missing Data, Second Edition. John Wiley: Hoboken New Jersey, pp. 59-60.</obo:IAO_0000119>
<rdfs:label xml:lang="en">data imputation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200062 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200062">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200085"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200197"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">continuum mass spectrum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A continuum mass spectrum is a data transformation that contains the full profile of the detected signals for a given ion.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: James Malone</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">PERSON: Tina Hernandez-Boussard</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Tina Boussard</obo:IAO_0000119>
<rdfs:label xml:lang="en">continuum mass spectrum analysis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200063 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200063">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200085"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200197"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">characteristic path length calculation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Quantifying subgraph navigability based on shortest-path length averaged over all pairs of subgraph vertices</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON: Tina Hernandez-Boussard</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Tina Hernandez-Boussard</obo:IAO_0000119>
<rdfs:label xml:lang="en">characteristic path length calculation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200064 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200064">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200085"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200197"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">centroid mass spectrum</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A centroid mass spectrum is a data transformation in which many points are used to delineate a mass spectral peak, is converted into mass-centroided data by a data compression algorithm. The centroided mass peak is located at the weighted center of mass of the profile peak. The normalized area of the peak provides the mass intensity data.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person:Tina Hernandez-Boussard</obo:IAO_0000117>
<obo:IAO_0000118>centroid mass spectrum calculation</obo:IAO_0000118>
<obo:IAO_0000118>centroiding</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">centroid mass spectrum</obo:IAO_0000119>
<rdfs:label xml:lang="en">centroid mass spectrum analysis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200066 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200066">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200073"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000175"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001265"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000791"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">Holm-Bonferroni family-wise error rate correction method</obo:IAO_0000111>
<obo:IAO_0000112>t-tests were used with the type I error adjusted for multiple comparisons, Holm's correction (HOLM 1979), and false discovery rate, http://www.genetics.org/cgi/content/full/172/2/1179</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a data transformation that performs more than one hypothesis test simultaneously, a closed-test procedure, that controls the familywise error rate for all the k hypotheses at level α in the strong sense. Objective: multiple testing correction</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">2011-03-14: [PRS]. Class Label has been changed to address the conflict with the definition
Also added restriction to specify the output to be a FWER adjusted p-value
The 'editor preferred term' should be removed</obo:IAO_0000116>
<obo:IAO_0000117>Person:Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>WEB: http://en.wikipedia.org/wiki/Holm%E2%80%93Bonferroni_method</obo:IAO_0000119>
<rdfs:label xml:lang="en">Holm-Bonferroni family-wise error rate correction method</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200070 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200070">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200080"/>
<obo:IAO_0000111 xml:lang="en">edge weighting</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Edge weighting is the substitution or transformation of edge length using numerical data. Data input include a symmetric adjacency matrix for a network and a second data set, for example a list of interactor pairs and a confidence score associated with the experimental detection of each pair's interaction. Each element in the adjacency matrix is transformed or replaced with the corresponding number in the second data set. Output data are a modified adjacency matrix reflecting the transformed state of the network.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Tina Hernandez-Boussard</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">editor</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">was classified under algorithm class which is not acceptable super-class
TO BE DEALT WITH STILL BY RICHARD. JAMES</obo:IAO_0000232>
<rdfs:label xml:lang="en">edge weighting</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200071 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200071">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200169"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200167"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">loess transformation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A loess transformation is a data transformation that takes as input a collection of real number pairs (x, y) and, after performing (one or more) loess fittings, utilizes the resulting curves to transform each (x, y) in the input into (x, y-f(x)) where f(x) is one of the fitted curves.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OTHER: Editor's generalization based on MGED Ontology term</obo:IAO_0000119>
<rdfs:label xml:lang="en">loess transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200072 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200072">
<owl:equivalentClass>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000656"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200174"/>
</owl:Restriction>
</owl:unionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200000"/>
<obo:IAO_0000111 xml:lang="en">curve fitting data transformation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A curve fitting is a data transformation that has objective curve fitting and that consists of finding a curve which matches a series of data points and possibly other constraints.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">WEB: http://en.wikipedia.org/wiki/Curve_fitting</obo:IAO_0000119>
<rdfs:label xml:lang="en">curve fitting data transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200073 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200073">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001265"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200089"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000791"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">family wise error rate correction method</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A family wise error rate correction method is a multiple testing procedure that controls the probability of at least one false positive.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">2011-03-31: [PRS].
creating a defined class by specifying the necessary output of dt
allows correct classification of FWER dt</obo:IAO_0000116>
<obo:IAO_0000117>Monnie McGee</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">FWER correction</obo:IAO_0000118>
<obo:IAO_0000119>Dudoit, Sandrine and van der Laan, Mark J. (2008) Multiple Testing Procedures with Applications to Genomics. New York: Springer , p. 19</obo:IAO_0000119>
<rdfs:label xml:lang="en">family wise error rate correction method</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200074 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200074">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200050"/>
<obo:IAO_0000111 xml:lang="en">submatrix extraction</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">When presented with the data from an expression microarray experiment in the form of a matrix, whose rows correspond to genes and whose columns correspond to samples, if one filters some of the genes and/or some of the samples out, the resulting data set corresponds to a submatrix of the original set.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A submatrix extraction is a projection whose input is a matrix and whose output is a matrix obtained by selecting certain rows and columns from the input. (Note that, if one represents the input matrix as a vector obtained by concatenating its rows, then extracting a submatrix is equivalent to projecting this vector into that composed by the entries belonging to the rows and columns of interest from the input matrix.)</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">Note that this can be considered as a special case of projection if one represents the input matrix as a vector obtained by concatenating its rows. Then extracting a submatrix is equivalent to projecting this vector into the entries belonging to the rows and columns of interest from the input matrix.</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">WEB: http://en.wikipedia.org/wiki/Submatrix</obo:IAO_0000119>
<rdfs:label xml:lang="en">submatrix extraction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200075 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200075">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200074"/>
<obo:IAO_0000111 xml:lang="en">row submatrix extraction</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">When presented with the data from an expression microarray experiment in the form of a matrix, whose rows correspond to genes and whose columns correspond to samples, if one filters some of the genes out, the resulting data set corresponds to a row submatrix of the original set.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A row submatrix extraction is a submatrix extraction where all the columns of the input matrix are retained and selection only occurs on the rows.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Elisabetta Manduchi</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">PERSON: James Malone</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">PERSON: Melanie Courtot</obo:IAO_0000119>
<rdfs:label xml:lang="en">row submatrix extraction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200076 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200076">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200074"/>
<obo:IAO_0000111 xml:lang="en">column submatrix extraction</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">When presented with the data from an expression microarray experiment in the form of a matrix, whose rows correspond to genes and whose columns correspond to samples, if one filters some of the samples out, the resulting data set corresponds to a column submatrix of the original set.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A column submatrix extraction is a submatrix extraction where all the rows of the input matrix are retained and selection only occurs on the columns.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Elisabetta Manduchi</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">PERSON: James Malone</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">PERSON: Melanie Courtot</obo:IAO_0000119>
<rdfs:label xml:lang="en">column submatrix extraction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200077 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200077">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200171"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200182"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200157"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200172"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">gating</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">Gating is a property-based vector selection with the objective of partitioning a data vector set into vector subsets based on dimension values of individual vectors (events), in which vectors represent individual physical particles (often cells) of a sample and dimension values represent light intensity qualities as measured by flow cytometry.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Josef Spidlen</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Richard Scheuermann</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Ryan Brinkman</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: James Malone</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">PERSON: Josef Spidlen</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">PERSON: Richard Scheuermann</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">PERSON: Ryan Brinkman</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">PERSON:Melanie Courtot</obo:IAO_0000119>
<rdfs:label xml:lang="en">gating</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200078 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200078">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200166"/>
<obo:IAO_0000111 xml:lang="en">descriptive statistical calculation objective</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A descriptive statistical calculation objective is a data transformation objective which concerns any calculation intended to describe a feature of a data set, for example, its center or its variability.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Monnie McGee</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Elisabetta Manduchi</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">PERSON: James Malone</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">PERSON: Melanie Courtot</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">PERSON: Monnie McGee</obo:IAO_0000119>
<rdfs:label xml:lang="en">descriptive statistical calculation objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200079 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200079">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200170"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200181"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200184"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000674"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200177"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000679"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000425"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200078"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">arithmetic mean calculation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An arithmetic mean calculation is a descriptive statistics calculation in which the mean is calculated by taking the sum of all of the observations in a data set divided by the total number of observations. It gives a measure of the 'center of gravity' for the data set. It is also known as the first moment.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Monnie McGee</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: James Malone</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">PERSON: Monnie McGee</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">From Monnie's file comments - need to add moment_calculation and center_calculation roles but they don't exist yet - (editor note added by James Jan 2008)</obo:IAO_0000232>
<rdfs:label xml:lang="en">arithmetic mean calculation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200080 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200080">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200000"/>
<obo:IAO_0000111 xml:lang="en">network analysis</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A data transformation that takes as input data that describes biological networks in terms of the node (a.k.a. vertex) and edge graph elements and their characteristics and generates as output properties of the constituent nodes and edges, the sub-graphs, and the entire network.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Richard Scheuermann</obo:IAO_0000117>
<obo:IAO_0000118>network topology analysis</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">PERSON: Richard Scheuermann</obo:IAO_0000119>
<rdfs:label xml:lang="en">network analysis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200081 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200081">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200166"/>
<obo:IAO_0000111 xml:lang="en">sequence analysis objective</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A sequence analysis objective is a data transformation objective which aims to analyse some ordered biological data for sequential patterns.</obo:IAO_0000115>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: James Malone</obo:IAO_0000119>
<rdfs:label xml:lang="en">sequence analysis objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200082 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200082">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200000"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200196"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>longitudinal data analysis</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Longitudinal analysis is a data transformation used to perform repeated observations of the same items over long periods of time.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: James Malone</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Tina Boussard</obo:IAO_0000117>
<obo:IAO_0000118>correlation analysis</obo:IAO_0000118>
<obo:IAO_0000118 xml:lang="en">longitudinal data analysis</obo:IAO_0000118>
<rdfs:label xml:lang="en">longitudinal data analysis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200083 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200083">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200166"/>
<obo:IAO_0000111 xml:lang="en">survival analysis objective</obo:IAO_0000111>
<obo:IAO_0000112>Kaplan meier data transformation</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A data transformation objective which has the data transformation aims to model time to event data (where events are e.g. death and or disease recurrence); the purpose of survival analysis is to model the underlying distribution of event times and to assess the dependence of the event time on other explanatory variables</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: James Malone</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Tina Boussard</obo:IAO_0000117>
<obo:IAO_0000118>survival analysis</obo:IAO_0000118>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Survival_analysis</obo:IAO_0000119>
<rdfs:label xml:lang="en">survival analysis objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200085 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200085">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200197"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200000"/>
<obo:IAO_0000111 xml:lang="en">mass spectrometry analysis</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A data transformation which has the objective of spectrum analysis.</obo:IAO_0000115>
<rdfs:label xml:lang="en">mass spectrometry analysis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200086 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200086">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200180"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200000"/>
<obo:IAO_0000111 xml:lang="en">spread calculation data transformation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A spread calculation is a data transformation that has objective spread calculation.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000119>EDITOR</obo:IAO_0000119>
<rdfs:label xml:lang="en">spread calculation data transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200088 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200088">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200194"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200083"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">Kaplan Meier</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a nonparametric (actuarial) data transformation technique for estimating time-related events. It is a univariate analysis that estimates the probability of the proportion of subjects in remission at a particular time, starting from the initiation of active date (time zero), and takes into account those lost to follow-up or not yet in remission at end of study (censored)</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: James Malone</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Tina Boussard</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Kaplan%E2%80%93Meier_estimator</obo:IAO_0000119>
<rdfs:label xml:lang="en">Kaplan Meier</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200089 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200089">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000791"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000668"/>
<obo:IAO_0000111>multiple testing correction method</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A multiple testing correction method is a hypothesis test performed simultaneously on M > 1 hypotheses. Multiple testing procedures produce a set of rejected hypotheses that is an estimate for the set of false null hypotheses while controlling for a suitably define Type I error rate</obo:IAO_0000115>
<obo:IAO_0000117>Monnie McGee</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">multiple testing procedure</obo:IAO_0000118>
<obo:IAO_0000119>PAPER: Dudoit, Sandrine and van der Laan, Mark J. (2008) Multiple Testing Procedures with Applications to Genomics. New York: Springer , p. 9-10.</obo:IAO_0000119>
<rdfs:label xml:lang="en">multiple testing correction method</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200091 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200091">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200166"/>
<obo:IAO_0000111>inter-rater reliability objective</obo:IAO_0000111>
<obo:IAO_0000112>A study was conducted to determine the inter-rater reliability of common clinical examination procedures proposed to identify patients with lumbar segmental instability.
Examples include joint-probability of agreement, Cohen's kappa and the related Fleiss' kappa, inter-rater correlation, concordance correlation coefficient and intra-class correlation.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a data transformation objective of determining the concordance or agreement between human judges.</obo:IAO_0000115>
<obo:IAO_0000117>Person:Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000117>Person:Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000118>inter-rater agreement</obo:IAO_0000118>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Inter-rater_reliability</obo:IAO_0000119>
<rdfs:label xml:lang="en">inter-rater reliability objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200092 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200092">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200073"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000175"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001265"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000791"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">Westfall and Young family wise error rate correction</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Is a data transformation process in which the Westfall and Young method is applied with the aim of controlling for multiple testing</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">2011-03-31: [PRS].
specified input and output of dt which were missing</obo:IAO_0000116>
<obo:IAO_0000116 xml:lang="en">PRS: 2011-03-31: set specified input and specified output to the data transformation</obo:IAO_0000116>
<obo:IAO_0000117>Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">Westfall and Young FWER correction</obo:IAO_0000118>
<rdfs:label xml:lang="en">Westfall and Young family wise error rate correction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200093 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200093">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200000"/>
<obo:IAO_0000111 xml:lang="en">polynomial transformation</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">a*x+b, with a non-zero, is a polynomial of degree one in one variable; a*x^2+b*x+c, with a nonzero, is a polynomial of degree 2 in 1
variable; a*x*y+b*y+c, with a non-zero, is a polynomial of degree 2 in 2 variables (x and y); a_1*x_1+...+a_n*x_n+b, with at least one of the a_i's non-zero, is a polynomial of degree one in n variables</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A polynomial transformation is a data transformation that is obtained through a polynomial, where a polynomial is a mathematical expression involving a sum of powers in one or more variables multiplied by coefficients (e.g. see http://mathworld.wolfram.com/Polynomial.html). The number of variables and the degree are properties of a polynomial. The degree of a polynomial is the highest power of its terms, where the terms of a polynomial are the individual summands with the coefficients omitted.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">WEB: http://mathworld.wolfram.com/Polynomial.html</obo:IAO_0000119>
<rdfs:label xml:lang="en">polynomial transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200094 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200094">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200169"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200167"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">logarithmic transformation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A logarithmic transformation is a data transformation consisting in the application of the logarithm function with a given base a (where a>0 and a is not equal to 1) to a (one dimensional) positive real number input. The logarithm function with base a can be defined as the inverse of the exponential function with the same base. See e.g. http://en.wikipedia.org/wiki/Logarithm.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">WEB: http://en.wikipedia.org/wiki/Logarithm</obo:IAO_0000119>
<rdfs:label xml:lang="en">logarithmic transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200095 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200095">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200169"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200167"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">exponential transformation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An exponential transformation is a data transformation consisting in the application of the exponential function with a given base a (where a>0 and a is typically not equal to 1) to a (one dimensional) real number input. For alternative definitions and properties of this function see, e.g., http://en.wikipedia.org/wiki/Exponential_function and http://en.wikipedia.org/wiki/Characterizations_of_the_exponential_function.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">WEB: http://en.wikipedia.org/wiki/Characterizations_of_the_exponential_function</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">WEB: http://en.wikipedia.org/wiki/Exponential_function</obo:IAO_0000119>
<rdfs:label xml:lang="en">exponential transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200097 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200097">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200000"/>
<obo:IAO_0000111>non-negative matrix factorization</obo:IAO_0000111>
<obo:IAO_0000112>Non-negative matrix factorization is used in text mining where document-term matrix is constructed with the weights of various terms (typically weighted word frequency information) from a set of documents. This matrix is factored into a term-feature and a feature-document matrix.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Non negative matrix factorization is a data transformation in which factorises a matrix and which forces that all elements must be equal to or greater than zero.</obo:IAO_0000115>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Non-negative_matrix_factorization</obo:IAO_0000119>
<rdfs:label xml:lang="en">non-negative matrix factorization</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200098 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200098">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200169"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200167"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>soft independent modeling of class analogy analysis</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Soft independent modeling by class analogy (SIMCA) is a descriptive statistics method for supervised classification of data. The method requires a training data set consisting of samples (or objects) with a set of attributes and their class membership. The term soft refers to the fact the classifier can identify samples as belonging to multiple classes and not necessarily producing a classification of samples into non-overlapping classes.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Tina Hernandez-Boussard</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">SIMCA</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">WEB: http://en.wikipedia.org/wiki/Soft_independent_modelling_of_class_analogies</obo:IAO_0000119>
<rdfs:label xml:lang="en">soft independent modeling of class analogy analysis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200099 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200099">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000663"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200106"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200175"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000023"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200179"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000648"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">discriminant function analysis</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">Discriminant function analysis is a form of discriminant analysis used to determine which variables discriminate between two or more naturally occurring groups. Analysis is used to determine which variable(s) are the best predictors of a particular outcome.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Tina Hernandez-Boussard</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">WEB: http://www.statsoft.com/textbook/stdiscan.html</obo:IAO_0000119>
<rdfs:label xml:lang="en">discriminant function analysis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200100 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200100">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200106"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200171"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200172"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">canonical variate analysis</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">canonical variate analysis is a form of discriminant analysis that takes several continuous predictor variables and uses the entire set to predict several criterion variables, each of which is also continuous. CVA simultaneously calculates a linear composite of all x variables and a linear composite of all y variables. Unlike other multivariate techniques, these weighted composites are derived in pairs. Each linear combination is called a canonical variate and takes the general linear form.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Tina Hernandez-Boussard</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">CVA</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">WEB: http://en.wikipedia.org/wiki/Canonical_analysis</obo:IAO_0000119>
<rdfs:label xml:lang="en">canonical variate analysis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200101 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200101">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000663"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200106"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200175"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000023"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200179"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000648"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">linear discriminant functional analysis</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">Linear discriminant functional analysis (LDFA) is a multivariate technique used in special applications where there are several intact groups (random assignment may be impossible) and they have been measured on several independent measures. Thus, you will want to describe how these groups differ on the basis of these measures. In this case, classification and prediction is the main objective.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Tina Hernandez-Boussard</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Tina Hernandez-Boussard</obo:IAO_0000119>
<rdfs:label xml:lang="en">linear discriminant functional analysis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200102 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200102">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200000"/>
<obo:IAO_0000111 xml:lang="en">regression analysis method</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">Regression analysis is a descriptive statistics technique that examines the relation of a dependent variable (response variable) to specified independent variables (explanatory variables). Regression analysis can be used as a descriptive method of data analysis (such as curve fitting) without relying on any assumptions about underlying processes generating the data.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Tina Hernandez-Boussard</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">BOOK: Richard A. Berk, Regression Analysis: A Constructive Critique, Sage Publications (2004) 978-0761929048</obo:IAO_0000119>
<rdfs:label xml:lang="en">regression analysis method</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200103 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200103">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200102"/>
<obo:IAO_0000111 xml:lang="en">multiple linear regression analysis</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">multiple linear regression is a regression method that models the relationship between a dependent variable Y, independent variables Xi, i = 1, ..., p, and a random term epsilon. The model can be written as
Y = \beta_0 + \beta_1 X_1 + \beta_2 X_2 + \cdots +\beta_p X_p + \varepsilon
where \beta_0 = 0 is the intercept ("constant" term), the \beta_i s are the respective parameters of independent variables, and p is the number of parameters to be estimated in the linear regression.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Tina Hernandez-Boussard</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">WEB:http://en.wikipedia.org/wiki/Linear_regression</obo:IAO_0000119>
<rdfs:label xml:lang="en">multiple linear regression analysis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200104 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200104">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200102"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200175"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000648"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200178"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">principal component regression</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">The Principal Component Regression method is a regression analysis method that combines the Principal Component Analysis (PCA)spectral decomposition with an Inverse Least Squares (ILS) regression method to create a quantitative model for complex samples. Unlike quantitation methods based directly on Beer's Law which attempt to calculate the absorbtivity coefficients for the constituents of interest from a direct regression of the constituent concentrations onto the spectroscopic responses, the PCR method regresses the concentrations on the PCA scores.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Tina Hernandez-Boussard</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">WEB: : http://www.thermo.com/com/cda/resources/resources_detail/1,2166,13414,00.html</obo:IAO_0000119>
<rdfs:label xml:lang="en">principal component regression</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200105 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200105">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200102"/>
<obo:IAO_0000111 xml:lang="en">partial least square regression analysis</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">Partial least squares regression is an extension of the multiple linear regression model (see, e.g., Multiple Regression or General Stepwise Regression). In its simplest form, a linear model specifies the (linear) relationship between a dependent (response) variable Y, and a set of predictor variables, the X's, so that
Y = b0 + b1X1 + b2X2 + ... + bpXp
In this equation b0 is the regression coefficient for the intercept and the bi values are the regression coefficients (for variables 1 through p) computed from the data.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Tina Hernandez-Boussard</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">PLS-RA</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">ARTICLE: de Jong, S. (1993). SIMPLS: An alternative approach to partial least squares regression. Chemometrics and Intelligent Laboratory Systems, 18: 251-263.</obo:IAO_0000119>
<rdfs:label xml:lang="en">partial least square regression analysis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200106 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200106">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200000"/>
<obo:IAO_0000111 xml:lang="en">discriminant analysis</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">Discriminant function analysis is used to determine which variables discriminate between two or more naturally occurring groups. Analysis is used to determine which variable(s) are the best predictors of a particular outcome.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Tina Hernandez-Boussard</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">WEB: http://www.statsoft.com/textbook/stdiscan.html</obo:IAO_0000119>
<rdfs:label xml:lang="en">discriminant analysis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200107 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200107">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200106"/>
<obo:IAO_0000111 xml:lang="en">partial least square discriminant analysis</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">PLS Discriminant Analysis (PLS-DA) is a discriminant analysis performed in order to sharpen the separation between groups of observations, by hopefully rotating PCA (Principal Components Analysis) components such that a maximum separation among classes is obtained, and to understand which variables carry the class separating information.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">PLS-DA</obo:IAO_0000118>
<obo:IAO_0000119>WEB: http://www.camo.com/rt/Resources/pls-da.html</obo:IAO_0000119>
<rdfs:label xml:lang="en">partial least square discriminant analysis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200108 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200108">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200169"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200167"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">eh transformation</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">This type of transformation is typically used in flow cytometry.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An eh transformation is a data transformation obtained by applying the function EH described in what follows to a (one dimensional) real number input. EH(x)=exp(x*d/r)+b*(d/r)*x-1, if x>=0, and EH(x)=-exp(-x*d/r)+b*(d/r)*x+1, otherwise. Here exp denotes an exponential transformation and b, d, r are positive real constants with the objective of normalization.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Joseph Spliden</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Ryan Brinkman</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">WEB: http://flowcyt.sourceforge.net/gating/latest.pdf</obo:IAO_0000119>
<rdfs:label xml:lang="en">eh transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200109 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200109">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200169"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000451"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200167"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">b transformation</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">This type of transformation is typically used in flow cytometry.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A b transformation is a data transformation obtained by applying the function B described in what follows to a (one dimensional) real number input. B(x)= a*exp(b*x)-c*exp(-d*x)+f, where exp denotes an exponential transformation and a, b, c, d, f are real constants with a, b, c, d positive with the objective of normalization.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Joseph Spliden</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Ryan Brinkman</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">WEB: http://flowcyt.sourceforge.net/gating/latest.pdf</obo:IAO_0000119>
<rdfs:label xml:lang="en">b transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200110 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200110">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200169"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200167"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">s transformation</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">This type of transformation is typically used in flow cytometry.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An s transformation is a data transformation obtained by applying the function S described in what follows to a (one dimensional) real number input. S(x)=T*exp(w-m)*(exp(x-w)-(p^2)*exp((w-x)/p)+p^2-1) if x>=w, S(x)=-S(w-x) otherwise; where exp denotes an exponential_transformations, 'p^' denotes the exponential transformation with base p; T, w, m, p are real constants with T, m, and p positive and w non-negative, and where w and p are related by w=2p*ln(p)(p+1) with the objective of normalization.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Joseph Spliden</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Ryan Brinkman</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">WEB: http://flowcyt.sourceforge.net/gating/latest.pdf</obo:IAO_0000119>
<rdfs:label xml:lang="en">s transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200111 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200111">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000038"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000101"/>
</owl:unionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:allValuesFrom>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000038"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000101"/>
</owl:unionOf>
</owl:Class>
</owl:allValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>data visualization</obo:IAO_0000111>
<obo:IAO_0000112>Generation of a heatmap from a microarray dataset</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A planned process with the objective to graphically represent some data by inputing the data and outputting images, diagrams or animations.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Tina Boussard</obo:IAO_0000117>
<obo:IAO_0000118>data encoding as image</obo:IAO_0000118>
<obo:IAO_0000118 xml:lang="en">visualization</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">PERSON: Elisabetta Manduchi</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">PERSON: James Malone</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">PERSON: Melanie Courtot</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">PERSON: Tina Boussard</obo:IAO_0000119>
<obo:IAO_0000232>Possible future hierarchy might include this:
information_encoding
>data_encoding
>>image_encoding</obo:IAO_0000232>
<rdfs:label xml:lang="en">data visualization</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200113 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200113">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000663"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200175"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000023"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000648"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">similarity calculation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A similarity calculation is a data transformation that attaches to each pair of objects in the input a number that is meant to reflect how 'close' or 'similar' those objects are.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Elisabetta Manduchi</obo:IAO_0000119>
<rdfs:label xml:lang="en">similarity calculation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200114 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200114">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200113"/>
<obo:IAO_0000111 xml:lang="en">euclidean distance calculation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An euclidean distance calculation is a similarity calculation that attaches to each pair of real number vectors of the same dimension n the square root of the sum of the square differences between corresponding components. The smaller this number, the more similar the two vectors are considered.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Elisabetta Manduchi</obo:IAO_0000119>
<rdfs:label xml:lang="en">euclidean distance calculation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200115 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200115">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200113"/>
<obo:IAO_0000111 xml:lang="en">pearson correlation coefficient calculation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A pearson correlation coefficient calculation is a similarity calculation which attaches to each pair of random variables X and Y the ratio of their covariance by the product of their standard deviations. Given a series of n measurements of X and Y written as x_i and y_i where i = 1, 2, ..., n, then their Pearson correlation coefficient refers to the "sample correlation coefficient" and is written as the sum over i of the ratios (x_i-xbar)*(y_i-ybar)/((n-1)*s_x*s_y) where xbar and ybar are the sample means of X and Y , s_x and s_y are the sample standard deviations of X and Y. The closer the pearson correlation coefficient is to 1, the more similar the inputs are considered.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Elisabetta Manduchi</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">WEB: http://en.wikipedia.org/wiki/Correlation</obo:IAO_0000119>
<rdfs:label xml:lang="en">pearson correlation coefficient calculation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200116 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200116">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200072"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200174"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">loess fitting</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A loess fitting is a curve fitting obtained by localized regression. The latter refers to fitting a polynomial (straight line, quadratic, cubic, etc) to data values within a window covering a fraction of the total number of observations. As the window slides along the axis, a new polynomial is fit to the observations falling within the window. This continues until all points are fit with a local polynomial. The results are then smoothed together to form a curve. The smoothness of loess fits is controlled by a smoothing parameter (often denoted as alpha, usually between 1/4 and 1) and the degree of the polynomial that is fitted by the method (usually denoted by lambda).</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Monnie McGee</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">ARTICLE: Mathematical details of loess fits are given in Cleveland, William (1993) Visualizing Data. Hobart Press, Summit, New Jersey, pp. 94-101.</obo:IAO_0000119>
<rdfs:label xml:lang="en">loess fitting</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200117 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200117">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200181"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200184"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000674"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200177"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200078"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">mode calculation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A mode calculation is a descriptive statistics calculation in which the mode is calculated which is the most common value in a data set. It is most often used as a measure of center for discrete data.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Monnie McGee</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: James Malone</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">PERSON: Monnie McGee</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">From Monnie's file comments - need to add center_calculation role but it doesn't exist yet - (editor note added by James Jan 2008)</obo:IAO_0000232>
<rdfs:label xml:lang="en">mode calculation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200118 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200118">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200184"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200078"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">quantile calculation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A quantile calculation is a descriptive statistics calculation in which the kth quantile is the data value for which an approximate k fraction of the data is less than or equal to that value. See http://www.stat.wvu.edu/SRS/Modules/Quantiles/quantiles.html for details.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Monnie McGee</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">WEB: http://www.stat.wvu.edu/SRS/Modules/Quantiles/quantiles.html</obo:IAO_0000119>
<rdfs:label xml:lang="en">quantile calculation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200119 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200119">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200181"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200184"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000674"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200177"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200078"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">median calculation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A median calculation is a descriptive statistics calculation in which the midpoint of the data set (the 0.5 quantile) is calculated. First, the observations are sorted in increasing order. For an odd number of observations, the median is the middle value of the sorted data. For an even number of observations, the median is the average of the two middle values.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Monnie McGee</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: James Malone</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">PERSON: Monnie McGee</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">From Monnie's file comments - need to add center_calculation role but it doesn't exist yet - (editor note added by James Jan 2008)</obo:IAO_0000232>
<rdfs:label xml:lang="en">median calculation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200120 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200120">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200086"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200184"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200078"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200180"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">variance calculation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A variance calculation is a descriptive statistics calculation in which the variance is defined as the average squared distance of each observation in the data set to the mean of the data set. It is also known as the second central moment.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Monnie McGee</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Monnie McGee</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">From Monnie's file comments - need to add spread_calculation and moment_calculation roles but they don't exist yet - (editor note added by James Jan 2008)</obo:IAO_0000232>
<rdfs:label xml:lang="en">variance calculation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200121 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200121">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200086"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200184"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200078"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200180"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">standard deviation calculation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A standard deviation calculation is a descriptive statistics calculation defined as the square root of the variance. Also thought of as the average distance of each value to the mean.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Monnie McGee</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Monnie McGee</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">From Monnie's file comments - need to add spread calculation role but they doesn't exist yet - (editor note added by James Jan 2008)</obo:IAO_0000232>
<rdfs:label xml:lang="en">standard deviation calculation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200122 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200122">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200086"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200184"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200078"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200180"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">interquartile-range calculation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The interquartile range is a descriptive statistics calculation defined as the difference between the 0.75 quantile and the 0.25 quantile for a set of data.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Monnie McGee</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Monnie McGee</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">From Monnie's file comments - need to add spread calculation role but they doesn't exist yet - (editor note added by James Jan 2008)</obo:IAO_0000232>
<rdfs:label xml:lang="en">interquartile-range calculation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200123 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200123">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200181"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200184"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000674"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200177"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200078"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">skewness calculation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A skewness calculation is a descriptive statistics calculation defined as a parameter that describes how much a distribution (or a data set) varies from a bell-shaped curve. See http://www.riskglossary.com/link/skewness.htm for details. It is also known as the third central moment</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Monnie McGee</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">WEB: http://www.riskglossary.com/link/skewness.htm</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">From Monnie's file comments - need to add moment calculation role but they doesn't exist yet - (editor note added by James Jan 2008)</obo:IAO_0000232>
<rdfs:label xml:lang="en">skewness calculation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200124 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200124">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200086"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200184"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200078"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200180"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">kurtosis calculation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A kurtosis calculation is a descriptive statistics calculation defined as a parameter that measures how large or small the tails of a distribution are relative to the mean. For details, see http://davidmlane.com/hyperstat/A53638.html</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Monnie McGee</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">WEB: http://davidmlane.com/hyperstat/A53638.html</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">From Monnie's file comments - need to add moment calculation role but they doesn't exist yet - (editor note added by James Jan 2008)</obo:IAO_0000232>
<rdfs:label xml:lang="en">kurtosis calculation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200125 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200125">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200000"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200189"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">data combination</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A data transformation in which individual input data elements and values are merged together into a output set of data elements and values.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Richard Scheuermann</obo:IAO_0000117>
<obo:IAO_0000118>data pooling</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">editor</obo:IAO_0000119>
<rdfs:label xml:lang="en">data combination</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200126 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200126">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200080"/>
<obo:IAO_0000111 xml:lang="en">network graph construction</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A network analysis in which an input data set describing objects and relationships between objects is transformed into an output representation of these objects as nodes and the relationships as edges of a network graph.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Richard Scheuermann</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Richard Scheuermann</obo:IAO_0000119>
<rdfs:label xml:lang="en">network graph construction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200127 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200127">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200126"/>
<obo:IAO_0000111 xml:lang="en">weighted network graph construction</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A network graph construction in which an input data set describing objects and quantitative relationships between objects is transformed into and output representation of these objects as nodes and the quantitative relationships as weighted edges of a network graph.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Richard Scheuermann</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Richard Scheuermann</obo:IAO_0000119>
<rdfs:label xml:lang="en">weighted network graph construction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200128 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200128">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200126"/>
<obo:IAO_0000111 xml:lang="en">directed network graph construction</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A network graph construction in which an input data set describing objects and directional relationships between objects is transformed into and output representation of these objects as nodes and the directional relationships as directed edges of a network graph.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Richard Scheuermann</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Richard Scheuermann</obo:IAO_0000119>
<rdfs:label xml:lang="en">directed network graph construction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200129 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200129">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200080"/>
<obo:IAO_0000111 xml:lang="en">node quality calculation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A network analysis in which an input data set describing node objects and edge relationships between node objects is used to determine the output quality of one of the node objects in the network.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Richard Scheuermann</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Richard Scheuermann</obo:IAO_0000119>
<rdfs:label xml:lang="en">node quality calculation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200130 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200130">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200129"/>
<obo:IAO_0000111 xml:lang="en">node degree calculation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A node quality calculation in which an input data set describing object nodes and relationship edges between object nodes is used to enumerate the number of unique relationships of an individual object node.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Richard Scheuermann</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Richard Scheuermann</obo:IAO_0000119>
<rdfs:label xml:lang="en">node degree calculation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200131 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200131">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200129"/>
<obo:IAO_0000111 xml:lang="en">quantitative node degree calculation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A node quality calculation in which an input data set describing object nodes and quantitative relationship edges between object nodes is used to sum all of the quantitative relationships of an individual object node.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Richard Scheuermann</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Richard Scheuermann</obo:IAO_0000119>
<rdfs:label xml:lang="en">quantitative node degree calculation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200132 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200132">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200129"/>
<obo:IAO_0000111 xml:lang="en">node in-degree calculation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A node quality calculation in which an input data set describing object nodes and directional relationship edges between object nodes is used to enumerate the number of unique relationships pointing into an individual object node.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Richard Scheuermann</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Richard Scheuermann</obo:IAO_0000119>
<rdfs:label xml:lang="en">node in-degree calculation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200133 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200133">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200129"/>
<obo:IAO_0000111 xml:lang="en">node out-degree calculation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A node quality calculation in which an input data set describing object nodes and directional relationship edges between object nodes is used to enumerate the number of unique relationships pointing out of an individual object node.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Richard Scheuermann</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Richard Scheuermann</obo:IAO_0000119>
<rdfs:label xml:lang="en">node out-degree calculation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200134 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200134">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200129"/>
<obo:IAO_0000111 xml:lang="en">node shortest path identification</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A node quality calculation in which a path describing the shortest path needed to transverse through connected nodes and edges to arrive at a specific target node in the network.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Richard Scheuermann</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Richard Scheuermann</obo:IAO_0000119>
<rdfs:label xml:lang="en">node shortest path identification</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200135 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200135">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200080"/>
<obo:IAO_0000111 xml:lang="en">edge quality calculation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A network analysis in which an input data set describing node objects and edge relationships between node objects is used to determine the output quality of one of the edge relationships in the network.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Richard Scheuermann</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Richard Scheuermann</obo:IAO_0000119>
<rdfs:label xml:lang="en">edge quality calculation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200136 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200136">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200135"/>
<obo:IAO_0000111 xml:lang="en">edge betweenness calculation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">An edge quality calculation in which the input is a data sets of shortest paths between all pairs of node in the network and the output is the sum of all shortest paths that traverse the specific edge.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Richard Scheuermann</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Richard Scheuermann</obo:IAO_0000119>
<rdfs:label xml:lang="en">edge betweenness calculation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200137 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200137">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200080"/>
<obo:IAO_0000111 xml:lang="en">network subgraph quality calculation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A network analysis in which an input data set describing node objects and edge relationships between node objects is used to determine the output quality of a subgraph partition of the network.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Richard Scheuermann</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Richard Scheuermann</obo:IAO_0000119>
<rdfs:label xml:lang="en">network subgraph quality calculation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200138 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200138">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200137"/>
<obo:IAO_0000111 xml:lang="en">subgraph degree calculation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A network subgraph quality calculation in which an input data set describing subgraphs and relationship edges between subgraphs and other network objects is used to enumerate the number of unique relationships of an individual subgraph.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Richard Scheuermann</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Richard Scheuermann</obo:IAO_0000119>
<rdfs:label xml:lang="en">subgraph degree calculation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200139 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200139">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200137"/>
<obo:IAO_0000111 xml:lang="en">quantitative subgraph degree calculation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A network subgraph quality calculation in which an input data set describing subgraphs and quantitative relationship edges between subgraphs and other network objects is used to sum the quantitative relationships of an individual subgraph.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Richard Scheuermann</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Richard Scheuermann</obo:IAO_0000119>
<rdfs:label xml:lang="en">quantitative subgraph degree calculation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200140 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200140">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200000"/>
<obo:IAO_0000111>mathematical feature</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">feature is a (parent_class) that describes a characteristic, trait or quality of a data transformation</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">This class is temporary and will be placed outside of data transformation ultimately (if it still remains at all after review)</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: James Malone</obo:IAO_0000119>
<rdfs:label xml:lang="en">mathematical feature</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200141 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200141">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200140"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000292"/>
<owl:someValuesFrom rdf:resource="http://www.w3.org/2001/XMLSchema#float"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>log base</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The log base is a feature of a logarithmic function which is defined in http://en.wikipedia.org/wiki/Logarithm. Its value can be any positive real number different from 1.</obo:IAO_0000115>
<obo:IAO_0000117>Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000118>logarithm base</obo:IAO_0000118>
<obo:IAO_0000118>logarithmic base</obo:IAO_0000118>
<obo:IAO_0000119>WEB: http://en.wikipedia.org/wiki/Logarithm</obo:IAO_0000119>
<rdfs:label xml:lang="en">log base</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200143 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200143">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200137"/>
<obo:IAO_0000111 xml:lang="en">subgraph in-degree calculation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A network subgraph quality calculation in which an input data set describing subgraphs and directional relationship edges between subgraphs and other network objects is used to enumerate the number of unique relationships pointing into an individual subgraph.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Richard Scheuermann</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Richard Scheuermann</obo:IAO_0000119>
<rdfs:label xml:lang="en">subgraph in-degree calculation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200144 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200144">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200137"/>
<obo:IAO_0000111 xml:lang="en">subgraph out-degree calculation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A network subgraph quality calculation in which an input data set describing subgraphs and relationship edges between subgraphs and other network objects is used to enumerate the number of unique relationships pointing out of an individual subgraph.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Richard Scheuermann</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Richard Scheuermann</obo:IAO_0000119>
<rdfs:label xml:lang="en">subgraph out-degree calculation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200145 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200145">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200137"/>
<obo:IAO_0000111 xml:lang="en">intra subgraph connectivity calculation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A network subgraph quality calculation in which an input data set describing internal nodes, edges and node degrees is used to determine the average node degree within the subgraph.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Richard Scheuermann</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Richard Scheuermann</obo:IAO_0000119>
<rdfs:label xml:lang="en">intra subgraph connectivity calculation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200146 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200146">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200137"/>
<obo:IAO_0000111 xml:lang="en">subgraph modularity calculation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A network subgraph quality calculation in which an input data set of subgraph in-degree and out-degree qualities is used to calculate the ratio of indegree to outdegree as a measure of modularity.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Richard Scheuermann</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Richard Scheuermann</obo:IAO_0000119>
<rdfs:label xml:lang="en">subgraph modularity calculation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200147 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200147">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200080"/>
<obo:IAO_0000111 xml:lang="en">network graph quality calculation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A network analysis in which an input data set describing node objects and edge relationships between node objects is used to determine the output quality of the network as a whole.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Richard Scheuermann</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Richard Scheuermann</obo:IAO_0000119>
<rdfs:label xml:lang="en">network graph quality calculation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200149 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200149">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200169"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200167"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">unit-variance scaling</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A unit-variance scaling is a data transformation that divides all measurements of a variable by the standard deviation of that variable.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">autoscaling</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">PMID:16762068</obo:IAO_0000119>
<rdfs:label xml:lang="en">unit-variance scaling</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200150 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200150">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200000"/>
<obo:IAO_0000111>MA transformation</obo:IAO_0000111>
<obo:IAO_0000112>MA transformations are typically used in microarray data analyses. In this context, the g_i and r_i represent the reporter intensities in the two channels of a 2-channel assay or the reporter intensities in two related one-channel assays. Typically the base used for the logarithm is 2.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">An MA transformation is a data transformation which takes as input a collection of data points (g_1, r_1), (g_2, r_2), ..., (g_n, r_n) with the r_i and g_i positive real numbers, and whose output is the collection of data points (A_1, M_1), (A_2, M_2), ..., (A_n, M_n) where, for each i, A_i=(log(g_i)+log(r_i))/2 and M_i=log(r_i)-log(g_i). Here log denotes a logarithmic transformation.</obo:IAO_0000115>
<obo:IAO_0000117>Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Elisabetta Manduchi</obo:IAO_0000119>
<rdfs:label>MA transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200151 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200151">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200140"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000292"/>
<owl:someValuesFrom rdf:resource="http://www.w3.org/2001/XMLSchema#float"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>exponential base</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The exponential base is a feature of an exponential function which is defined in http://en.wikipedia.org/wiki/Exponential_function. Its value can be any positive real number (typically different from 1).</obo:IAO_0000115>
<obo:IAO_0000117>Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000119>WEB: http://en.wikipedia.org/wiki/Exponential_function</obo:IAO_0000119>
<rdfs:label xml:lang="en">exponential base</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200152 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200152">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200140"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000292"/>
<owl:someValuesFrom rdf:resource="http://www.w3.org/2001/XMLSchema#nonNegativeInteger"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>polynomial degree</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The polynomial degree is a feature of a polynomial function defined as the highest power of the polynomial's terms, where the terms of a polynomial are the individual summands with the coefficients omitted.</obo:IAO_0000115>
<obo:IAO_0000117>Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Elisabetta Manduchi</obo:IAO_0000119>
<rdfs:label xml:lang="en">polynomial degree</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200153 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200153">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200140"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000292"/>
<owl:someValuesFrom rdf:resource="http://www.w3.org/2001/XMLSchema#integer"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>number of variables</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The number of variables is a feature of any function (including polynomial functions) with domain contained in an n-dimensional vector space and is defined as n, the dimension of such space.</obo:IAO_0000115>
<obo:IAO_0000117>Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Elisabetta Manduchi</obo:IAO_0000119>
<rdfs:label xml:lang="en">number of variables</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200154 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200154">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200042"/>
<obo:IAO_0000111 xml:lang="en">agglomerative hierarchical clustering</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">An agglomerative hierarchical clustering is a hierarchical clustering which starts with separate clusters and then successively combines these clusters until there is only one cluster remaining.</obo:IAO_0000115>
<obo:IAO_0000117>Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000118>bottom-up hierarchical clustering</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">PERSON: Elisabetta Manduchi</obo:IAO_0000119>
<rdfs:label xml:lang="en">agglomerative hierarchical clustering</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200155 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200155">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200042"/>
<obo:IAO_0000111 xml:lang="en">divisive hierarchical clustering</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A divisive hierarchical clustering is a hierarchical clustering which starts with a single cluster and then successively splits resulting clusters until only clusters of individual objects remain.</obo:IAO_0000115>
<obo:IAO_0000117>Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000118>top-down hierarchical clustering</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">PERSON: Elisabetta Manduchi</obo:IAO_0000119>
<rdfs:label xml:lang="en">divisive hierarchical clustering</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200156 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200156">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200000"/>
<obo:IAO_0000111 xml:lang="en">data partitioning</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">Data partitioning is a data transformation with the objective of partitioning or separating input data into output subsets.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Melanie Courtot</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">PERSON: Richard Scheuermann</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">PERSON: Ryan Brinkman</obo:IAO_0000119>
<rdfs:label xml:lang="en">data partitioning</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200157 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200157">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200166"/>
<obo:IAO_0000111 xml:lang="en">data vector reduction objective</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">Data vector reduction is a data transformation objective in which k m-dimensional input vectors are reduced to j m-dimensional output vectors, where j is smaller than k.</obo:IAO_0000115>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Richard H. Scheuermann</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: Richard H. Scheuermann</obo:IAO_0000119>
<rdfs:label xml:lang="en">data vector reduction objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200160 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200160">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200089"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000791"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">generalized family wise error rate correction method</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A generalized FWER correction method is a multiple testing procedure that controls the probability of at least k+1 false positives, where k is a user-supplied integer.</obo:IAO_0000115>
<obo:IAO_0000117>Monnie McGee</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">gFWER correction</obo:IAO_0000118>
<obo:IAO_0000119>Dudoit, Sandrine and van der Laan, Mark J. (2008) Multiple Testing Procedures with Applications to Genomics. New York: Springer , p. 19</obo:IAO_0000119>
<rdfs:label xml:lang="en">generalized family wise error rate correction method</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200161 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200161">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200089"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000662"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000791"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">quantile number of false positives correction method</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A quantile number of false positives correction method is a MTP that controls for the pth quantile of the distribution of the number of false positives out of the total number of tests performed'</obo:IAO_0000115>
<obo:IAO_0000117>Monnie McGee</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">QNFP</obo:IAO_0000118>
<obo:IAO_0000119>Dudoit, Sandrine and van der Laan, Mark J. (2008) Multiple Testing Procedures with Applications to Genomics. New York: Springer , p. 19</obo:IAO_0000119>
<rdfs:label xml:lang="en">quantile number of false positives correction method</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200162 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200162">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200089"/>
<rdfs:subClassOf>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000791"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">tail probability for the proportion of false positives correction method</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A TPPFP correction method is a MTP that controls the probability that the proportion of false positives among all rejected hypotheses is no greater than a constant q, where q is between 0 and 1.</obo:IAO_0000115>
<obo:IAO_0000117>Monnie McGee</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">TPPFP correction method</obo:IAO_0000118>
<obo:IAO_0000119>Dudoit, Sandrine and van der Laan, Mark J. (2008) Multiple Testing Procedures with Applications to Genomics. New York: Springer , p. 20</obo:IAO_0000119>
<rdfs:label xml:lang="en">tail probability for the proportion of false positives correction method</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200163 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200163">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001442"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200089"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000175"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000791"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">false discovery rate correction method</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">The false discovery rate is a data transformation used in multiple hypothesis testing to correct for multiple comparisons. It controls the expected proportion of incorrectly rejected null hypotheses (type I errors) in a list of rejected hypotheses. It is a less conservative comparison procedure with greater power than familywise error rate (FWER) control, at a cost of increasing the likelihood of obtaining type I errors. .</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">2011-03-31: [PRS].
creating a defined class by specifying the necessary output of dt
allows correct classification of FDR dt</obo:IAO_0000116>
<obo:IAO_0000117>Monnie McGee</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">FDR correction method</obo:IAO_0000118>
<obo:IAO_0000119>Dudoit, Sandrine and van der Laan, Mark J. (2008) Multiple Testing Procedures with Applications to Genomics. New York: Springer , p. 21 and http://www.wikidoc.org/index.php/False_discovery_rate</obo:IAO_0000119>
<rdfs:label xml:lang="en">false discovery rate correction method</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200164 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200164">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200089"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000662"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000791"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">proportion of expected false positives correction method</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A proportion of expected false positives correction method is a multiple testing procedure that controls the ratio of the expected value of the numbers of false positives to the expected value of the numbers of rejected hypotheses.</obo:IAO_0000115>
<obo:IAO_0000117>Monnie McGee</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">PEFP correction method</obo:IAO_0000118>
<obo:IAO_0000119>Dudoit, Sandrine and van der Laan, Mark J. (2008) Multiple Testing Procedures with Applications to Genomics. New York: Springer , p. 21</obo:IAO_0000119>
<rdfs:label xml:lang="en">proportion of expected false positives correction method</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200165 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200165">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200089"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000662"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000791"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">quantile proportion of false positives correction method</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A quantile proportion of false positives correction method is a multiple testing procedure that controls the pth quantile of the distribution of the proportion of false positives among the rejected hypothesis (false discovery rate).</obo:IAO_0000115>
<obo:IAO_0000117>Monnie McGee</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">QPFP correction method</obo:IAO_0000118>
<obo:IAO_0000119>Dudoit, Sandrine and van der Laan, Mark J. (2008) Multiple Testing Procedures with Applications to Genomics. New York: Springer , p. 21</obo:IAO_0000119>
<rdfs:label xml:lang="en">quantile proportion of false positives correction method</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200166 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200166">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000005"/>
<obo:IAO_0000111 xml:lang="en">data transformation objective</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">normalize objective</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An objective specification to transformation input data into output data</obo:IAO_0000115>
<obo:IAO_0000116>Modified definition in 2013 Philly OBI workshop</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: James Malone</obo:IAO_0000119>
<rdfs:label xml:lang="en">data transformation objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200167 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200167">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200166"/>
<obo:IAO_0000111 xml:lang="en">data normalization objective</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Quantile transformation which has normalization objective can be used for expression microarray assay normalization and it is referred to as "quantile normalization", according to the procedure described e.g. in PMID 12538238.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A normalization objective is a data transformation objective where the aim is to remove
systematic sources of variation to put the data on equal footing in order
to create a common base for comparisons.</obo:IAO_0000115>
<obo:IAO_0000117>Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117>Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Elisabetta Manduchi</obo:IAO_0000119>
<obo:IAO_0000119>PERSON: Helen Parkinson</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">PERSON: James Malone</obo:IAO_0000119>
<rdfs:label xml:lang="en">data normalization objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200168 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200168">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200166"/>
<obo:IAO_0000111 xml:lang="en">correction objective</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Type I error correction</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A correction objective is a data transformation objective where the aim is to correct for error, noise or other impairments to the input of the data transformation or derived from the data transformation itself</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: James Malone</obo:IAO_0000119>
<obo:IAO_0000119>PERSON: Melanie Courtot</obo:IAO_0000119>
<rdfs:label xml:lang="en">correction objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200169 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200169">
<owl:equivalentClass>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000451"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200167"/>
</owl:Restriction>
</owl:unionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200000"/>
<obo:IAO_0000111 xml:lang="en">normalization data transformation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A normalization data transformation is a data transformation that has objective normalization.</obo:IAO_0000115>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: James Malone</obo:IAO_0000119>
<rdfs:label xml:lang="en">normalization data transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200170 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200170">
<owl:equivalentClass>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000679"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000425"/>
</owl:Restriction>
</owl:unionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200000"/>
<obo:IAO_0000111 xml:lang="en">averaging data transformation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An averaging data transformation is a data transformation that has objective averaging.</obo:IAO_0000115>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: James Malone</obo:IAO_0000119>
<rdfs:label xml:lang="en">averaging data transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200171 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200171">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200172"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200000"/>
<obo:IAO_0000111 xml:lang="en">partitioning data transformation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A partitioning data transformation is a data transformation that has objective partitioning.</obo:IAO_0000115>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: James Malone</obo:IAO_0000119>
<rdfs:label xml:lang="en">partitioning data transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200172 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200172">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200166"/>
<obo:IAO_0000111 xml:lang="en">partitioning objective</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">A k-means clustering which has partitioning objective is a data transformation in which the input data is partitioned into k output sets.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A partitioning objective is a data transformation objective where the aim is to generate a collection of disjoint non-empty subsets whose union equals a non-empty input set.</obo:IAO_0000115>
<obo:IAO_0000117>Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Elisabetta Manduchi</obo:IAO_0000119>
<rdfs:label xml:lang="en">partitioning objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200173 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200173">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200168"/>
<obo:IAO_0000111 xml:lang="en">background correction objective</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A background correction objective is a data transformation objective where the aim is to remove irrelevant contributions from the measured signal, e.g. those due to instrument noise or sample preparation.</obo:IAO_0000115>
<obo:IAO_0000117>Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Elisabetta Manduchi</obo:IAO_0000119>
<rdfs:label xml:lang="en">background correction objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200174 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200174">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200166"/>
<obo:IAO_0000111 xml:lang="en">curve fitting objective</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A curve fitting objective is a data transformation objective in which the aim is to find a curve which matches a series of data points and possibly other constraints.</obo:IAO_0000115>
<obo:IAO_0000117>Elisabetta Manduchi</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Elisabetta Manduchi</obo:IAO_0000119>
<rdfs:label xml:lang="en">curve fitting objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200175 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200175">
<owl:equivalentClass>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000648"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200178"/>
</owl:Restriction>
</owl:unionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200000"/>
<obo:IAO_0000111 xml:lang="en">class discovery data transformation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A class discovery data transformation (sometimes called unsupervised classification) is a data transformation that has objective class discovery.</obo:IAO_0000115>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<obo:IAO_0000118>clustering data transformation</obo:IAO_0000118>
<obo:IAO_0000118>unsupervised classification data transformation</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">PERSON: James Malone</obo:IAO_0000119>
<rdfs:label xml:lang="en">class discovery data transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200176 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200176">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000673"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000675"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>Fisher's exact test</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Fisher's exact test is a data transformation used to determine if there are nonrandom associations between two Fisher's exact test is a statistical significance test used in the analysis of contingency tables where sample sizes are small where the significance of the deviation from a null hypothesis can be calculated exactly, rather than relying on an approximation that becomes exact in the limit as the sample size grows to infinity, as with many statistical tests.</obo:IAO_0000115>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<obo:IAO_0000119>WEB:http://mathworld.wolfram.com/FishersExactTest.html</obo:IAO_0000119>
<rdfs:label>Fisher's exact test</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200177 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200177">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200166"/>
<obo:IAO_0000111 xml:lang="en">center calculation objective</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">A mean calculation which has center calculation objective is a data transformation in which the center of the input data is discovered through the calculation of a mean average.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A center calculation objective is a data transformation objective where the aim is to calculate the center of an input data set.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: James Malone</obo:IAO_0000119>
<rdfs:label xml:lang="en">center calculation objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200178 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200178">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200166"/>
<obo:IAO_0000111 xml:lang="en">class discovery objective</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A class discovery objective (sometimes called unsupervised classification) is a data transformation objective where the aim is to organize input data (typically vectors of attributes) into classes, where the number of classes and their specifications are not known a priori. Depending on usage, the class assignment can be definite or probabilistic.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000118>clustering objective</obo:IAO_0000118>
<obo:IAO_0000118 xml:lang="en">discriminant analysis objective</obo:IAO_0000118>
<obo:IAO_0000118 xml:lang="en">unsupervised classification objective</obo:IAO_0000118>
<obo:IAO_0000119>PERSON: Elisabetta Manduchi</obo:IAO_0000119>
<obo:IAO_0000119>PERSON: James Malone</obo:IAO_0000119>
<rdfs:label xml:lang="en">class discovery objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200179 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200179">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200166"/>
<obo:IAO_0000111 xml:lang="en">class prediction objective</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A class prediction objective (sometimes called supervised classification) is a data transformation objective where the aim is to create a predictor from training data through a machine learning technique. The training data consist of pairs of objects (typically vectors of attributes) and
class labels for these objects. The resulting predictor can be used to attach class labels to any valid novel input object. Depending on usage, the prediction can be definite or probabilistic. A classification is learned from the training data and can then be tested on test data.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000118>classification objective</obo:IAO_0000118>
<obo:IAO_0000118 xml:lang="en">supervised classification objective</obo:IAO_0000118>
<obo:IAO_0000119>PERSON: Elisabetta Manduchi</obo:IAO_0000119>
<obo:IAO_0000119>PERSON: James Malone</obo:IAO_0000119>
<rdfs:label xml:lang="en">class prediction objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200180 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200180">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200166"/>
<obo:IAO_0000111 xml:lang="en">spread calculation objective</obo:IAO_0000111>
<obo:IAO_0000112>Spread calculation can be achieved by use of a standard deviation, which measures distance from the mean</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">is a data transformation objective whereby the aim is to the calculate the spread of a dataset, spread is a descriptive statistic which describes the variability of values in a data set.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">Awaiting English definition from Monnie McGee</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000117>Person:Helen Parkinson</obo:IAO_0000117>
<rdfs:label xml:lang="en">spread calculation objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200181 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200181">
<owl:equivalentClass>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000674"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200177"/>
</owl:Restriction>
</owl:unionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200000"/>
<obo:IAO_0000111 xml:lang="en">center calculation data transformation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A center calculation data transformation is a data transformation that has objective of center calculation.</obo:IAO_0000115>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: James Malone</obo:IAO_0000119>
<rdfs:label xml:lang="en">center calculation data transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200182 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200182">
<owl:equivalentClass>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000676"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200157"/>
</owl:Restriction>
</owl:unionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000707"/>
<obo:IAO_0000111 xml:lang="en">data vector reduction data transformation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A data vector reduction is a data transformation that has objective data vector reduction and that consists of reducing the input vectors k to a smaller number of output vectors j, where j<k.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: James Malone</obo:IAO_0000119>
<rdfs:label xml:lang="en">data vector reduction data transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200183 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200183">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200166"/>
<obo:IAO_0000111 xml:lang="en">scaling objective</obo:IAO_0000111>
<obo:IAO_0000112>Scaling gene expression data for cross platform analysis http://www.springerprotocols.com/Abstract/doi/10.1007/978-1-59745-454-4_13</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">is a data transformation objective where all, or some of a data set is adjusted by some data transformation according to some scale, for example a user defined minimum or maximum</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">Awaiting English definition from Monnie McGee</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000117>Person:Helen Parkinson</obo:IAO_0000117>
<rdfs:label xml:lang="en">scaling objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200184 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200184">
<owl:equivalentClass>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000649"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200078"/>
</owl:Restriction>
</owl:unionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200000"/>
<obo:IAO_0000111 xml:lang="en">descriptive statistical calculation data transformation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A descriptive statistical calculation data transformation is a data transformation that has objective descriptive statistical calculation and which concerns any calculation intended to describe a feature of a data set, for example, its center or its variability.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: James Malone</obo:IAO_0000119>
<rdfs:label xml:lang="en">descriptive statistical calculation data transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200185 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200185">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200183"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200000"/>
<obo:IAO_0000111 xml:lang="en">scaling data transformation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A scaling data transformation is a data transformation that has objective scaling.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PERSON: James Malone</obo:IAO_0000119>
<rdfs:label xml:lang="en">scaling data transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200186 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200186">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200168"/>
<obo:IAO_0000111 xml:lang="en">error correction objective</obo:IAO_0000111>
<obo:IAO_0000112>Application of a multiple testing correction method</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">An error correction objective is a data transformation objective where the aim is to remove (correct for) erroneous contributions arising from the input data, or the transformation itself.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">James Malone, Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: James Malone</obo:IAO_0000119>
<rdfs:label xml:lang="en">error correction objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200187 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200187">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200081"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200000"/>
<obo:IAO_0000111 xml:lang="en">sequence analysis data transformation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A sequence analysis data transformation is a data transformation that has objective sequence analysis and has the aim of analysing ordered biological data for sequential patterns.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000119>EDITOR</obo:IAO_0000119>
<rdfs:label xml:lang="en">sequence analysis data transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200188 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200188">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200172"/>
<obo:IAO_0000111 xml:lang="en">cross validation objective</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A cross validation objective is a data transformation objective in which the aim is to partition a sample of data into subsets such that the analysis is initially performed on a single subset, while the other subset(s) are retained for subsequent use in confirming and validating the initial analysis.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">rotation estimation objective</obo:IAO_0000118>
<obo:IAO_0000119>WEB: http://en.wikipedia.org/wiki/Cross_validation</obo:IAO_0000119>
<rdfs:label xml:lang="en">cross validation objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200189 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200189">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200166"/>
<obo:IAO_0000111>merging objective</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">merging of columns from two different data sets</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A merging objective is a data transformation objective in which the data transformation has the aim of performing a union of two or more sets.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">combining objective</obo:IAO_0000118>
<obo:IAO_0000119>PERSON: Data Transformation Branch</obo:IAO_0000119>
<rdfs:label xml:lang="en">merging objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200190 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200190">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200111"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000037"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000179"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000180"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000183"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000184"/>
</owl:unionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000648"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>clustered data visualization</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A data visualization which has input of a clustered data set and produces an output of a report graph which is capable of rendering data of this type.</obo:IAO_0000115>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<rdfs:label>clustered data visualization</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200191 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200191">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200111"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000306"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000118"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>gene list visualization</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Adata visualization which has input of a gene list and produces an output of a report graph which is capable of rendering data of this type.</obo:IAO_0000115>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<rdfs:label>gene list visualization</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200192 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200192">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200111"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000180"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000184"/>
</owl:unionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000023"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>classified data visualization</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A data visualization which has input of a classified data set and produces an output of a report graph which is capable of rendering data of this type.</obo:IAO_0000115>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<rdfs:label>classified data visualization</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200193 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200193">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200111"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000079"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000179"/>
</owl:unionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000660"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>background corrected data visualization</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A data visualization which has input of a background corrected data set and produces an output of a report graph which is capable of rendering data of this type.</obo:IAO_0000115>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<obo:IAO_0000117>Monnie McGee</obo:IAO_0000117>
<rdfs:label>background corrected data visualization</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200194 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200194">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200083"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200000"/>
<obo:IAO_0000111>survival analysis data transformation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A data transformation which has the objective of performing survival analysis.</obo:IAO_0000115>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: James Malone</obo:IAO_0000119>
<rdfs:label>survival analysis data transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200195 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200195">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200194"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200083"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>proportional hazards model estimation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Proportional hazards model is a data transformation model to estimate the effects of different covariates influencing the times-to-failure of a system.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: James Malone</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Tina Boussard</obo:IAO_0000117>
<obo:IAO_0000118>Cox model</obo:IAO_0000118>
<obo:IAO_0000118>Cox proportional hazards model</obo:IAO_0000118>
<obo:IAO_0000119>WEB: http://en.wikipedia.org/wiki/Cox_proportional_hazards_model</obo:IAO_0000119>
<rdfs:label>proportional hazards model estimation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200196 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200196">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200166"/>
<obo:IAO_0000111>correlation study objective</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A data transformation objective in which correlation is obtained (often measured as a correlation coefficient, ρ) which indicates the strength and direction of a relationship between two random variables.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Tina Boussard</obo:IAO_0000117>
<rdfs:label>correlation study objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200197 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200197">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200166"/>
<obo:IAO_0000111>spectrum analysis objective</obo:IAO_0000111>
<obo:IAO_0000112>Calculation of characteristic path length in mass spectrometry</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">is a data transformation objective where the aim is to analyse some aspect of spectral data by some data transformation process.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Tina Boussard</obo:IAO_0000117>
<obo:IAO_0000117>Person:Helen Parkinson</obo:IAO_0000117>
<rdfs:label>spectrum analysis objective</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200198 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200198">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete tandem mass spectrometry</obo:IAO_0000111>
<obo:IAO_0000112>A precursor ion is selected in the first stage, allowed to fragment and then all resultant masses are scanned in the second mass analyzer and detected in the detector that is positioned after the second mass analyzer. This experiment is commonly performed to identify transitions used for quantification by tandem MS.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Tandem mass spectrometry is a data transformation that uses two or more analyzers separated by a region in which ions can be induced to fragment by transfer of energy (frequently by collision with other molecules.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: James Malone</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Tina Boussard</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Tina Boussard</obo:IAO_0000119>
<obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/OBI_0003540"/>
<rdfs:label>obsolete tandem mass spectrometry</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200199 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200199">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200085"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200197"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>gas chromatography mass spectrometry</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Gas chromatography mass spectrometry is a data transformation combining mass spectrometry and
gas chromatography for the qualitative as well as quantitative
determinations of compounds.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: James Malone</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Tina Boussard</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Tina Boussard</obo:IAO_0000119>
<rdfs:label>gas chromatography mass spectrometry</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200200 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200200">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000673"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000675"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>chi square test</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">The chi-square test is a data transformation with the objective of statistical hypothesis testing, in which the sampling distribution of the test statistic is a chi-square distribution when the null hypothesis is true, or any in which this is asymptotically true, meaning that the sampling distribution (if the null hypothesis is true) can be made to approximate a chi-square distribution as closely as desired by making the sample size large enough.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: James Malone</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Tina Boussard</obo:IAO_0000117>
<rdfs:label>chi square test</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0200201 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200201">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000673"/>
<obo:IAO_0000111>ANOVA</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A statistical hypothesis test in which the means of several groups are all equal.</obo:IAO_0000115>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<rdfs:label>ANOVA</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0300310 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0300310">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000115"/>
<obo:IAO_0000111>sequential design</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 17710740.Pharm Stat. 2007 Aug 20.Sequential design approaches for bioequivalence studies with crossover designs.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">Any design in which the decision as to whether to enroll the next patient, pair of patients, or block of patients is determined by whether the cumulative treatment difference for all previous patients is within specified limits. Enrollment is continued if the difference does not exceed the limits. It is terminated if it does</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>MUSC</obo:IAO_0000119>
<obo:IAO_0000232>Provenance: OCI</obo:IAO_0000232>
<rdfs:label>sequential design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0300311 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0300311">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
<obo:IAO_0000111>observation design</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 12387964.Lancet. 2002 Oct 12;360(9340):1144-9.Deficiency of antibacterial peptides in patients with morbus Kostmann: an observation study.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">observation design is a study design in which subjects are monitored in the absence of any active intervention by experimentalists.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>OBI branch derived</obo:IAO_0000119>
<rdfs:label>observation design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302714 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302714">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_collection (of entities of organismal origin)</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 18037794. Magn Reson Med Sci. 2007;6(3):139-46. Imaging of a large collection of human embryo using a super-parallel MR microscope.[the Orsay Museum has a nice collection of Impressionnist paintings]</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a collection is a bfo:aggregate object, that is a set of material object of the same kind</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Susanna Sansone</obo:IAO_0000117>
<obo:IAO_0000118>ensemble</obo:IAO_0000118>
<obo:IAO_0000118>group</obo:IAO_0000118>
<obo:IAO_0000118>set</obo:IAO_0000118>
<obo:IAO_0000119>PERSON: Philippe Rocca-Serra</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_collection (of entities of organismal origin)</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302716 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302716">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100051"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000652"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100051"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000953"/>
<obo:IAO_0000111>pool of specimens</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pool of specimens is a mixture of a population of samples which have been gathered from one or more sample populations, obtained by the physical process of mixing individual specimens, e.g. mixing the DNA collected from the individual fish.</obo:IAO_0000115>
<obo:IAO_0000116>check with advisors as to how to represent multiple instances of any class? a set of specimens which have been gathered from one or more sample_populations, obtained by the physical process of mixing individual specimens, e.g. mixing the DNA collected from the individual fish</obo:IAO_0000116>
<obo:IAO_0000117>PERSON: Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000119>GROUP: CEBS</obo:IAO_0000119>
<rdfs:label>pool of specimens</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302729 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302729">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000576"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0302732"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000576"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0302733"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000111 xml:lang="en">chemical solution</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PMID: 18289311.Anesth Analg. 2008 Apr;106(4):1078-86.Less impairment of hemostasis and reduced blood loss in pigs after resuscitation from hemorrhagic shock using the small-volume concept with hypertonic saline/hydroxyethyl starch as compared to administration of 4% gelatin or 6% hydroxyethyl starch solution.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A material entity that is made up of at least 2 scattered molecular aggregates, one playing the role of solvent and the other one playing the role of solute.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">liquid chemical solution</obo:IAO_0000118>
<obo:IAO_0000119>GROUP: OBI Biomaterial Branch</obo:IAO_0000119>
<rdfs:label xml:lang="en">chemical solution</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302731 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302731">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<obo:IAO_0000111>buffer role</obo:IAO_0000111>
<obo:IAO_0000112>A buffer of carbonic acid (H2CO3) and bicarbonate (HCO3-) is present in blood plasma, to maintain a pH between 7.35 and 7.45. http://en.wikipedia.org/wiki/Buffer_solution</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">a role which inheres in some molecular entity realized during the process of buffering</obo:IAO_0000115>
<obo:IAO_0000117>Person:Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000117>Person:Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>buffer</obo:IAO_0000118>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">buffer role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302732 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302732">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003610"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000685"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>solvent role</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PMID: 18373502.Transfusion. 2008 Mar 25. Solvent/detergent treatment of platelet concentrates enhances the release of growth factors.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">solvent role is a role which inheres in a molecular entity capable of ensuring the dissolution of another chemical entity and realized by the process of solvation</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">The class CHEBI:solvent is logically equivalent to this class, iff it is properly subsumed under the BFO:role branch. The label and textual definition of this CHEBI class are however misleadingly denoting the material entity that bears this role and not the role itself. The OBI modeling was needed as what is considered a solvent in a mixture can depend on the intent of the person creating the mixture. It would be great if this could be dealt with in CHEBI itself. See also https://github.com/obi-ontology/obi/issues/1771.</obo:IAO_0000116>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>adpated from wikipedia (http://en.wikipedia.org/wiki/Solvatation)</obo:IAO_0000119>
<rdfs:label xml:lang="en">solvent role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302733 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302733">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000685"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>solute role</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PMID: 18380397.Pharmazie. 2008 Feb;63(2):113-21.Deviations of drug solubility in water-cosolvent mixtures from the Jouyban-Acree model--effect of solute structure.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">solute role is a role played by a chemical entity which is dissolved by another chemical entity (the solvent) when creating a solution</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>adapted from wikipedia (http://en.wikipedia.org/wiki/Solute)</obo:IAO_0000119>
<rdfs:label xml:lang="en">solute role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302736 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302736">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001501"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001977"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000000"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000086"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000053"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000018"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000250"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000053"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000018"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000250"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHMO_0000087"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003368"/>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000439"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0006974"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>comet assay</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 18326531.Mutagenesis. 2008 Mar 6.Recommendations for design of the rat comet assay.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures DNA damage (DNA breakage) in eucaryotic cells exposed to a challenge by determining the size and shape of DNA migration by detecting fluorescently labeled DNA from a cell placed in an electric field using gel electrophoresis</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>SCGE assay</obo:IAO_0000118>
<obo:IAO_0000118>single cell gel electrophoresis assay</obo:IAO_0000118>
<obo:IAO_0000119>PMID:7686265</obo:IAO_0000119>
<rdfs:label>comet assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302737 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302737">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000435"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002692"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000415"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600014"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000809"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000101"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001305"/>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>PCR-SSCP assay</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 17334176.Hum Exp Toxicol. 2007 Jan;26(1):9-18.Is there a role for PCR-SSCP among the methods for missense mutation detection of TP53 gene?</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An assay that identifies DNA sequence variation (mutation, deletion, insertions) in target DNA sequences amplified using polymerase chain reaction using gel electrophoresis and denaturating conditions</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>polymerase chain reaction-single strand conformation polymorphism assay</obo:IAO_0000118>
<obo:IAO_0000119>PMID:18219595</obo:IAO_0000119>
<rdfs:label>PCR-SSCP assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302743 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302743">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_liver</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 2104732. Caudate lobe of the liver: anatomy, embryology, and pathology. AJR Am J Roentgenol. 1990 Jan;154(1):87-93.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">liver is an anatomical entity which constituent are mainly hepatocytes, which has a function of detoxification, hematopoietic center, glucose and fat metabolism management. liver is only found in animals , all Vertebrates and some families of invertebrates</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>GROUP: OBI Biomaterial Branch</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<rdfs:label>obsolete_liver</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302745 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302745">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_adipose tissue</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 18435934.Fatty acid composition of adipose tissue and blood in humans and its use as a biomarker of dietary intake.Prog Lipid Res. 2008 Apr 4.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">adipose tissue is a tissue which main constituents are adipocytes. adipose tissue can be classified base on its location (site) but also based on adipocyte subtypes (brown or white) which reflect functional differences and is only found in animals, Vertebrates or invertebrates.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>GROUP: OBI Biomaterial derived</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<rdfs:label>obsolete_adipose tissue</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302835 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302835">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_33839"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000803"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33839"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<obo:IAO_0000111>denatured polymer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Is a polymer which has lost secondary or tertiary structure</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Denaturation_%28biochemistry%29</obo:IAO_0000119>
<rdfs:label xml:lang="en">denatured polymer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302837 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302837">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0302899"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<obo:IAO_0000111>decapitated organism</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Ovarian development induced in decapitated female Culex pipiens pallens mosquitoes by infusion of physiological quantities of 20-hydroxyecdysone together with amino acids.
J Insect Physiol. 1998 May;44(5-6):525-528. PMID: 12770172</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">decapitated organism is an organism which has had it's head removed</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI Biomaterial</obo:IAO_0000119>
<rdfs:label xml:lang="en">decapitated organism</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302838 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302838">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0302911"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>validated information</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 20084519: "..Three of four interactions were validated via functional magnetic resonance imaging (fMRI) in an independent sample of healthy controls;..."</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">an information content entity which results from a validation process aimed at confirming a claim, a finding or a predicted information entity about a material entity or a process by experimental means.</obo:IAO_0000115>
<obo:IAO_0000117>Person:Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">validated information</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302840 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302840">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0302914"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>curated information</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 17344875: A curated compendium of phosphorylation motifs.Nat Biotechnol. 2007 Mar;25(3):285-6.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An information content entity that has undergone a digital curation performed by a curator for accuracy checks and compliance with curation requirements. Information which has been assessed for accuracy by domain experts.</obo:IAO_0000115>
<obo:IAO_0000116>2009-11-10 Bjoern Peters. Need to check if this was intended. overlap with 'edited information', and has the same logical restrictions.</obo:IAO_0000116>
<obo:IAO_0000116>2010-01-31 Philippe Rocca-Serra: restriction now changed to be the output of a digital curation process + reflected in example of usage and reference</obo:IAO_0000116>
<obo:IAO_0000117>Person:Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Person:Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">curated information</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302846 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302846">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0302900"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<obo:IAO_0000111>randomized group participant role</obo:IAO_0000111>
<obo:IAO_0000112>A person enrolled in a randomized clinical trial bears a randomized group participant role</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a role that borne by an organism and realized by some group randomization process</obo:IAO_0000115>
<obo:IAO_0000117>Person:Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<rdfs:label xml:lang="en">randomized group participant role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302847 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302847">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_33839"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600039"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33839"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<obo:IAO_0000111>methylated polymer</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Binding and penetration of methylated DNA into primary and transformed human cells.
Ann N Y Acad Sci. 2008 Aug;1137:36-40. PMID: 18837922</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A methylated polymer which has artificially acquired one or more methyl groups</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI Biomaterial</obo:IAO_0000119>
<rdfs:label xml:lang="en">methylated polymer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302859 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302859">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100026"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600043"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001151"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
<obo:IAO_0000111>genetically modified organism</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">A protocol for removal of antibiotic resistance cassettes from human embryonic stem cells genetically modified by homologous recombination or transgenesis.
Nat Protoc. 2008;3(10):1550-8. PMID: 18802436</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">an organism that is the output of a genetic transformation process</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI Biomaterial</obo:IAO_0000119>
<rdfs:label xml:lang="en">genetically modified organism</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302867 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302867">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0302910"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
<obo:IAO_0000111>predicted data item</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A data item that was generated on the basis of a calculation or logical reasoning</obo:IAO_0000115>
<obo:IAO_0000116>BP 12/21: Edited the incomplete definition from Philippe. It is still unclear to me if this should be a data item at all, or an information content entity. This will be important, because if we exclude predictions from data items, we will run into issues that we willl have to duplicate things like 'weight datum' etc. all of which can be predicted.</obo:IAO_0000116>
<obo:IAO_0000117>Philippe Rocca-Serra; Bjoern Peters</obo:IAO_0000117>
<rdfs:label xml:lang="en">predicted data item</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302868 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302868">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200029"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000451"/>
<obo:IAO_0000111>mean-centered data</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a data item which has been processed by a mean centering data transformation where each output value is produced by subtracting the mean from the inout value</obo:IAO_0000115>
<obo:IAO_0000117>Person:Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000117>Person:Philippe Rocca-Serra</obo:IAO_0000117>
<rdfs:label xml:lang="en">mean-centered data</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302874 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302874">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000310"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0302908"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>edited document</obo:IAO_0000111>
<obo:IAO_0000112>The OBI manuscript is (much) edited imformation</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A document which is the output of a document editing process</obo:IAO_0000115>
<obo:IAO_0000117>Person:Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<rdfs:label xml:lang="en">edited document</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302876 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302876">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000576"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000685"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000576"/>
<obo:IAO_0000111>dissolved material entity</obo:IAO_0000111>
<obo:IAO_0000112>Salt molecules that have been mixed into water</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A material entity that has been going through a process of being put into solution</obo:IAO_0000115>
<obo:IAO_0000117>Person:Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<rdfs:label xml:lang="en">dissolved material entity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302884 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302884">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600014"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000681"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>extraction</obo:IAO_0000111>
<obo:IAO_0000112>nucleic acid extraction using phenol chloroform</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A material separation in which a desired component of an input material is separated from the remainder</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">Current the output of material processing defined as the molecular entity, main component in the output material entity, rather than the material entity that have grain molecular entity.
'nucleic acid extract' is the output of 'nucleic acid extraction' and has grain 'nucleic acid'. However, the output of 'nucleic acid extraction' is 'nucleic acid' rather than 'nucleic acid extract'. We are aware of this issue and will work it out in the future.</obo:IAO_0000116>
<obo:IAO_0000117>Person:Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<rdfs:label xml:lang="en">extraction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302885 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302885">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600014"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000681"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000151"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>filtration</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PMID: 18524968.Filtration of CSF improves isolation of Mycobacteria.J Clin Microbiol. 2008 Jun 4.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">filtration is a process which separates components suspended in a fluid based on granularity properties relying on a filter device</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>OBI-Branch: adapted from wikipedia and wordnet</obo:IAO_0000119>
<rdfs:label xml:lang="en">filtration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302886 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302886">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600014"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000681"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400106"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>centrifugation</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PMID: 18428461.Purification of oligodendrocytes and their progenitors using immunomagnetic separation and Percoll gradient centrifugation. Curr Protoc Neurosci. 2001 May;Chapter 3:Unit 3.12.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">centrifugation is a process separating molecules by size or density using centrifugal forces generated by a spinning rotor. G-forces of several hundred thousand times gravity are generated in ultracentrifugation</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>adapted from http://www.fao.org/DOCREP/003/X3910E/X3910E06.htm</obo:IAO_0000119>
<rdfs:label xml:lang="en">centrifugation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302887 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302887">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>staining</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PMID: 18540298. Role of modified bleach method in staining of acid-fast bacilli in lymph node aspirates. Acta Cytol. 2008 May-Jun;52(3):325-8.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">Staining is a process which results in the addition a class-specific (DNA, proteins, lipids, carbohydrates) dye to a substrate to qualify or quantify the presence of a specific compound.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>adapted from Wikipedia: http://en.wikipedia.org/wiki/Staining</obo:IAO_0000119>
<rdfs:label xml:lang="en">staining</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302888 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302888">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>washing</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PMID: 6874122. Dialysis leucopenia--no correction after prolonged washing of the membrane. Int J Artif Organs. 1983 May;6(3):113-4.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">washing is a process by which a material entity acting as contaminant (e.g. excess staining reagent) is removed by application of one or more cycles of solution in flow.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>OBI-Branch</obo:IAO_0000119>
<rdfs:label xml:lang="en">washing</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302889 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302889">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400065"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>planned irradiation</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PMID: 18563778.Histological and modeling study of skin thermal injury to 2.0 mum laser irradiation.Lasers Surg Med. 2008 Jun 18;40(5):358-370.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A planned process by which a material entity is exposed to radiative energy, which could be ionizing radiation (such as gamma rays, X-rays, charged particles or neutrons) or non-ionizing radiation (such as UV light or microwaves)</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>adapted from wikipedia (http://en.wikipedia.org/wiki/Irradiation)</obo:IAO_0000119>
<rdfs:label xml:lang="en">planned irradiation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302890 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302890">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33839"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>polymerization</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PMID: 18517209. The electronic role of DNA-functionalized carbon nanotubes: efficacy for in situ polymerization of conducting polymer nanocomposites. J Am Chem Soc. 2008 Jun 25;130(25):7921-8. Epub 2008 Jun 3.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">polymerization is process by which molecular entity of small mass are aggregated in motifs over the course of a chemical reaction catalyzed by enzymes or other molecular entities acting as catalyst. polymerization results in molecular entity of high molecular weight</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">PRS:22102008: need to import catalyst from CHEBI 35223</obo:IAO_0000116>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>OBI-Branch</obo:IAO_0000119>
<rdfs:label xml:lang="en">polymerization</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302891 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302891">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600056"/>
<obo:IAO_0000111>trypsination</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">The use of mild trypsinization conditions in the detachment of endothelial cells to promote subsequent endothelialization on synthetic surfaces. Biomaterials. 2007 Sep;28(27):3928-35. PMID: 17570483</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">trypsination is a protease cleavage which uses enzyme trypsin to act on proteins present in an input material entity</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>OBI PA</obo:IAO_0000119>
<rdfs:label xml:lang="en">trypsination</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302892 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302892">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000427"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>enzymatic ligation</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PMID: 17853876. Enzymatic ligation assisted by nucleases: simultaneous ligation and digestion promote the ordered assembly of DNA. Nat Protoc. 2007;2(9):2198-202.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An enzymatic ligation is a planned process in which molecules are joined by covalent bonds through the action of an material entity with a ligase activity</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>OBI-Branch</obo:IAO_0000119>
<rdfs:label xml:lang="en">enzymatic ligation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302893 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302893">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000838"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000806"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>storage</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PMID: 18550121.Total Prostate Specific Antigen Stability Confirmed After Long-Term Storage of Serum at -80C. J Urol. 2008 Jun 10.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A planned process with the objective to preserve and protect material entities by placing them in an identified location which may have a controlled environment.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>OBI-Branch</obo:IAO_0000119>
<rdfs:label xml:lang="en">storage</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302894 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302894">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600006"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000000"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100060"/>
</owl:unionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>cell lysis</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PMID: 18484276.Cell lysis with dimethyl sulphoxide produces stable homogeneous solutions in the dichlorofluorescein oxidative stress assay. Free Radic Res. 2008 May;42(5):435-41.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">cell lysis is a process by which cell membrane integrity of live cells is compromised and leads to cell death. Cell lysis may be achieved by means of viral action or osmotic shock.</obo:IAO_0000115>
<obo:IAO_0000116>BP, JG, RV: There is also a need for the unplanned cell lysis, which is probably not in the scope of OBI, but should be linked to from this process.</obo:IAO_0000116>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>adapted from wikipedia [http://en.wikipedia.org/wiki/Lysis]</obo:IAO_0000119>
<rdfs:label xml:lang="en">cell lysis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302895 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302895">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000919"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400142"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>electrocution</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PMID: 9587208. Electrocution of horses and cattle. Vet Rec. 1998 Apr 4;142(14):376.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">electrocution is process by which electric current is applied to a material with quality alive and result the termination of life process.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>OBI branch</obo:IAO_0000119>
<rdfs:label xml:lang="en">electrocution</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302896 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302896">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000919"/>
<obo:IAO_0000111>cervical dislocation</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PMID: 18246869. Loss of cortical function in mice after decapitation, cervical dislocation, potassium chloride injection, and CO2 inhalation. Comp Med. 2007 Dec;57(6):570-3</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">cervical dislocation is a process by which a Vertebrate organism has its life terminated by rupturing spinal cord between cervical vertebrae induced by excessive mechanical torsion</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">PRS:21102008: Input must be restricted to Vertebrates (requires import from NCBI tax)</obo:IAO_0000116>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>OBI branch</obo:IAO_0000119>
<rdfs:label xml:lang="en">cervical dislocation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302897 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302897">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000919"/>
<obo:IAO_0000111>asphyxiation</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PMID: 18246869. Loss of cortical function in mice after decapitation, cervical dislocation, potassium chloride injection, and CO2 inhalation. Comp Med. 2007 Dec;57(6):570-</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">asphyxiation is a process by which oxygen supplies are restricted (by mechanical, e.g obstructing airways or chemical means, e.g. increasing CO2 partial pressure) resulting in termination of life in oxygen reliant organisms.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>OBI branch</obo:IAO_0000119>
<rdfs:label xml:lang="en">asphyxiation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302898 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302898">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000919"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>intentional overdosing</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">In vivo measurement of tumor blood oxygenation by near-infrared spectroscopy: immediate effects of pentobarbital overdose or carmustine treatment.
J Neurooncol. 1994;22(3):209-20. PMID: 7760097</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">intentional overdosing is a process by which an excess dose of a chemical compound is given with the intent of causing death</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">lethal injection</obo:IAO_0000118>
<obo:IAO_0000119>OBI Biomaterial</obo:IAO_0000119>
<rdfs:label xml:lang="en">intentional overdosing</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302899 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302899">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000919"/>
<obo:IAO_0000111>decapitation</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PMID: 18246869. Loss of cortical function in mice after decapitation, cervical dislocation, potassium chloride injection, and CO2 inhalation. Comp Med. 2007 Dec;57(6):570-</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">decapitation is a process by which the head of a living organism is physically removed from the body, usually resulting in rapid death (in the case of Rhodnius prolixus, it might take a bit longer..)</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>OBI-Branch</obo:IAO_0000119>
<rdfs:label xml:lang="en">decapitation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302900 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302900">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600015"/>
<obo:IAO_0000111>group randomization</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PMID: 18349405. Randomization reveals unexpected acute leukemias in Southwest Oncology Group prostate cancer trial. J Clin Oncol. 2008 Mar 20;26(9):1532-6.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A group assignment which relies on chance to assign materials to a group of materials in order to avoid bias in experimental set up.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>adapted from wikipedia [http://en.wikipedia.org/wiki/Randomization]</obo:IAO_0000119>
<rdfs:label xml:lang="en">group randomization</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302901 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302901">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_activation</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 18566411.Activation of the JAK/STAT-1 Signaling Pathway by IFN-{gamma} Can Down-Regulate Functional Expression of the MHC Class I-Related Neonatal Fc Receptor for IgG.J Immunol. 2008 Jul 1;181(1):449-63.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000124"/>
<obo:IAO_0000115 xml:lang="en">a process by which a material entity status is modified and conferred a capability of reacting (this sounds like a circular definition , hugh!)</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>OBI-Branch</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_activation</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302902 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302902">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>immobilization</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PMID: 18562258. The immobilization of proteins on biodegradable fibers via biotin-streptavidin bridges.Acta Biomater. 2008 May 23.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">immbolization is a process by which material entity become (possibly covalently but not necessarily) attached to the surface of another material entity used a substratum.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>OBI-Branch</obo:IAO_0000119>
<rdfs:label xml:lang="en">immobilization</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302903 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302903">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400110"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>nucleic acid hybridization</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PMID: 18555787.Quantitative analysis of DNA hybridization in a flowthrough microarray for molecular testing. Anal Biochem. 2008 May 27.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a planned process by which totally or partially complementary, single-stranded nucleic acids are combined into a single molecule called heteroduplex or homoduplex to an extent depending on the amount of complementarity.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>adapted from wikipedia [http://en.wikipedia.org/wiki/Nucleic_acid_hybridization]</obo:IAO_0000119>
<obo:OBI_0001847>hybridization assay</obo:OBI_0001847>
<rdfs:label xml:lang="en">nucleic acid hybridization</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302905 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302905">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0302732"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000318"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000038"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>elution</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PMID: 18549238.Theory and Application of the Two-Mode Gradient Elution in Liquid Chromatography Involving Simultaneous Changes in Temperature and Mobile-Phase Composition.Anal Chem. 2008 Jun 13.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">the process of extracting one material from another by washing with a solvent to remove adsorbed material from an adsorbent (as in washing of loaded ion-exchange resins to remove captured ions)</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>wordnet.princeton.edu/perl/webwn</obo:IAO_0000119>
<rdfs:label xml:lang="en">elution</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302906 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302906">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600014"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000681"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">DNA Subtraction</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PMID: 10718422. Identification of genes overexpressed in head and neck squamous cell carcinoma using a combination of complementary DNA subtraction and microarray analysis. Laryngoscope. 2000 Mar;110(3 Pt 1):374-81</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">a material separation process by which repetitive genomic DNA is removed during the construction of cDNA library.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>OBI-Branch</obo:IAO_0000119>
<rdfs:label xml:lang="en">DNA Subtraction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302908 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302908">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000310"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0302874"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>document editing</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Wax DB, Beilin Y, Hossain S, Lin HM, Reich DL.
Manual editing of automatically recorded data in an anesthesia information management system. Anesthesiology. 2008 Nov;109(5):811-5. PMID: 18946292</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">is a planned process with specified input original document and specified output edited document</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra and OBI consortium</obo:IAO_0000117>
<obo:IAO_0000119>adapted from wikipedia</obo:IAO_0000119>
<rdfs:label xml:lang="en">document editing</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302910 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302910">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>prediction</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Prediction of TF target sites based on atomistic models of protein-DNA complexes. BMC Bioinformatics. 2008 Oct 16;9(1):436. PMID: 18922190</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a process by which an event or an entity is described before it actually happens or is being discovered and identified.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">prediction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302911 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302911">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<obo:IAO_0000111>validation</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PMID: 18557814 . Chemical and genetic validation of dihydrofolate reductase-thymidylate synthase as a drug target in African trypanosomes. Mol Microbiol. 2008 Jun 16.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a planned process with objective to check that the accuracy or the quality of a claim or prediction satisfies some criteria and which is assessed by comparing with independent results</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>adapted from wordnet (wkipedia)</obo:IAO_0000119>
<rdfs:label xml:lang="en">validation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302912 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302912">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600033"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400142"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>electroporation</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PMID: 18551712. Microfluidic electroporation for selective release of intracellular molecules at the single-cell level. Electrophoresis. 2008 Jun 13.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a process in which a significant increase in the electrical conductivity and permeability of the cell plasma membrane caused by an externally applied electrical field. It is usually used in molecular biology as a way of introducing some substance into a cell, such as loading it with a molecular probe, a drug that can change the cell's function, or a piece of coding DNA</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>electropermeabilization</obo:IAO_0000118>
<obo:IAO_0000119>WEB:http://en.wikipedia.org/wiki/Electroporation</obo:IAO_0000119>
<rdfs:label xml:lang="en">electroporation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0302914 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302914">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000572"/>
<obo:IAO_0000111>digital curation</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PMID: 16901087. Supporting the curation of biological databases with reusable text mining.Genome Inform. 2005;16(2):32-44.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Digital curation is the process of establishing and developing long term repositories of digital assets for current and future reference by researchers, scientists, and historians, and scholars generally.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>wikipedia</obo:IAO_0000119>
<rdfs:label xml:lang="en">digital curation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400005 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400005">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400008"/>
<obo:IAO_0000111>A10-Analyzer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A A10 is a flow_cytometer_analyser manufactured by Apogee. It uses an arc lamp as a light source, with choices of 75W Xe, 75W Xe/Hg or 100W Hg arc lamps. It has filters and collectors for up to three fluorescent parameters and two scatter parameters. It uses analog electronics. The A10 can be used for measuring the properties of individual cells.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://www.apogeeflow.com/flow_cytometry_products.htm</obo:IAO_0000119>
<rdfs:label>A10-Analyzer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400006 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400006">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400008"/>
<obo:IAO_0000111>A40-MiniFCM</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A A40-MiniFCM is a flow_cytometer_analyser that allows for the choice of one of four lasers (375nm, 405nm,488nm, 532nm, 635nm), and PMTs and filters for collecting up to four parameters. It uses digital electronics. A military version of this cytometer is available as well. The A40-MiniFCM is geared towards the most demanding applications such as archaea, bacteria and large virus.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://www.apogeeflow.com/flow_cytometry_products.htm</obo:IAO_0000119>
<rdfs:label>A40-MiniFCM</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400007 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400007">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000393"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>analog-to-digital converter</obo:IAO_0000111>
<obo:IAO_0000112>The analog to digital converter transformed the analog output from the photomultiplier tube to a digital signal for collection.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An analog-to-digital_converter is an instrument that converts an infinite resolution analog signal to a finite resolution digital signal.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000118>A-D</obo:IAO_0000118>
<obo:IAO_0000118>A2D</obo:IAO_0000118>
<obo:IAO_0000119>http://en.wiktionary.org/wiki/Analog-to-Digital_Converter</obo:IAO_0000119>
<rdfs:label>analog-to-digital converter</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400008 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400008">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400044"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400043"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400065"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400079"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400082"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>flow cytometer analyzer</obo:IAO_0000111>
<obo:IAO_0000112>FACS Calibur, Luminex 100</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An analyser is a flow_cytometer that is used to measure properties of particles (whole cells, nuclei, chromosomes, diatoms, plankton, bacteria, viruses) by moving these particles through a detection chamber. An analyser is used to collect data for analysis.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://www.flocyte.com/FRTP/Resources/flow_cytometry_glossary.htm</obo:IAO_0000119>
<rdfs:label>flow cytometer analyzer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400009 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400009">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400065"/>
<obo:IAO_0000111>arc lamp</obo:IAO_0000111>
<obo:IAO_0000112>The Jablochkoff Candle</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Arc lamp is a light source that produces light by an electric arc (or voltaic arc). The lamp consists of two electrodes typically made of tungsten which are separated by a gas. The type of lamp is often named by the gas contained in the bulb; including neon, argon, xenon, krypton, sodium, metal halide, and mercury. The electric arc in an arc lamp consists of gas which is initially ionized by a voltage and is therefore electrically conductive. To start an arc lamp, usually a very high voltage is needed to ignite or strike the arc. This requires an electrical circuit sometimes called an igniter, which is part of a larger circuit called the ballast. The ballast supplies a suitable voltage and current to the lamp as its electrical characteristics change with temperature and time. Older cytometers may use arc lamps to irradiate particles at the interrogation point.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Arc_lamp</obo:IAO_0000119>
<rdfs:label>arc lamp</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400010 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400010">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400060"/>
<obo:IAO_0000111>argon ion laser</obo:IAO_0000111>
<obo:IAO_0000112>argon ion laser in a cytometer</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An argon-ion laser is an ion laser that uses argon ions as the lasing medium. These lasers are used primarily to emit light at wave lengths of 458 nm, 488 nm or 514.5 nm, though it is possible to use them to emit several wavelengths of blue and green light. Argon-ion lasers can emit light at many different wave lenghts, and excite a number of different flourochromes.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>John Quinn</obo:IAO_0000119>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Laser#Gas_lasers</obo:IAO_0000119>
<rdfs:label>argon ion laser</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400011 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400011">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400083"/>
<obo:IAO_0000111>avalanche photodiode</obo:IAO_0000111>
<obo:IAO_0000112>C30644E - InGaAs Avalanche Photodiode</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An avalanche photodiode is typically used to collect photons emitted by forward scatter because it is far less sensitive, and less likely o be burned out, than a PMT. A photodiode with high quantum efficiency and a mechanism for producing gains as high as a few thousand.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>Practical Flow Cytometry 4th Edition, Howard Shapiro, ISBN-10: 0471411256, ISBN-13: 978-0471411253</obo:IAO_0000119>
<rdfs:label>avalanche photodiode</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400012 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400012">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400008"/>
<obo:IAO_0000111>Bactiflow</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A Bactiflow is a flow_cytometer_analyser manufactured by Chemunex SA. It is a cell counter for bacteria and other micro organisms. Bacteria are stained with a fluorochrome and the number of particles that fluoresce are counted. The system uses digital electronics, a single laser and a single detector. An ALS version is available as well - Automatic Labeling System. The Bactiflow is specialized cytometer used exclusively for counting microbes.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://www.chemunex.com/products/chemframe.htm</obo:IAO_0000119>
<rdfs:label>Bactiflow</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400013 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400013">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400079"/>
<obo:IAO_0000111>band pass filter</obo:IAO_0000111>
<obo:IAO_0000112>530/30 BP filter, 585/42 BP filter</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A band pass filter is an optical filter that passes wavelengths of light within a certain range and rejects (attenuates) frequencies outside that range. The passed wavelengths are indicated in the specifications of the filter and its name. A 480/20 band-pass filter pass light with at wavelengths of 460 to 500 nm and attenuates all others.</obo:IAO_0000115>
<obo:IAO_0000117>Person:John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Band_pass_filter</obo:IAO_0000119>
<rdfs:label>band pass filter</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400014 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400014">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400099"/>
<obo:IAO_0000111>BioSorter1000</obo:IAO_0000111>
<obo:IAO_0000112>BioSorter 1000 at TSRI Flow Cytometry Core Facility</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A BioSorter1000 is a flow_cytometer_sorter manufactured by Union Biometrica. It includes analog electronics, 488/514 nm multi-line Argon-ion laser for fluorescence and a light stabilized 670 nm forward scatter laser for extinction and time-of-flight. It has filters and PMTs for 3 fluorescent parameters and photodiodes for scatter, time of flight, and extinction. The flow cell is quartz cuvette. The BioSorterTM 1000 is an instrument for analyzing and sorting objects from 200-600 microns in diameter.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://www.unionbio.com/products/BioSorter.html</obo:IAO_0000119>
<rdfs:label>BioSorter1000</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400015 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400015">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400099"/>
<obo:IAO_0000111>BioSorter2000</obo:IAO_0000111>
<obo:IAO_0000112>BioSorter 2000 at TSRI Flow Cytometry Core Facility</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A BioSorter2000 is a sorter manufactured by Union Biometrica. It includes analog electronics, 488/514 nm multi-line Argon-ion laser for fluorescence and a light stabilized 670 nm forward scatter laser for extinction and time-of-flight. It has filters and PMTs for 3 fluorescent parameters and photodiodes for scatter, time of flight, and extinction. The flow cell is quartz cuvette. The BioSorterTM 2000 is an instrument for analyzing and sorting objects from 500 microns to 1.5 millimeters in diameter.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://www.unionbio.com/products/BioSorter.html</obo:IAO_0000119>
<rdfs:label>BioSorter2000</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400016 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400016">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400099"/>
<obo:IAO_0000111>BioSorter250</obo:IAO_0000111>
<obo:IAO_0000112>BioSorter 250 at TSRI Flow Cytometry Core Facility</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A BioSorter250 is a flow_cytometer_sorter manufactured by Union Biometrica. It includes analog electronics, 488/514 nm multi-line Argon-ion laser for fluorescence and a light stabilized 670 nm forward scatter laser for extinction and time-of-flight. It has filters and PMTs for 3 fluorescent parameters and photodiodes for scatter, time of flight, and extinction. The flow cell is quartz cuvette. The BioSorterTM 250 is an instrument for analyzing and sorting objects from 40-200 microns in diameter.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://www.unionbio.com/products/BioSorter.html</obo:IAO_0000119>
<rdfs:label>BioSorter250</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400017 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400017">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400099"/>
<obo:IAO_0000111>BioSorter500</obo:IAO_0000111>
<obo:IAO_0000112>BioSorter 500 at TSRI Flow Cytometry Core Facility</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A BioSorter500 is a flow_cytometer_sorter manufactured by Union Biometrica. It includes analog electronics, 488/514 nm multi-line Argon-ion laser for fluorescence and a light stabilized 670 nm forward scatter laser for extinction and time-of-flight. It has filters and PMTs for 3 fluorescent parameters and photodiodes for scatter, time of flight, and extinction. The flow cell is quartz cuvette. The BioSorterTM 500 is an instrument for analyzing and sorting objects from 100-250 microns in diameter and less than 2mm in length.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://www.unionbio.com/products/BioSorter.html</obo:IAO_0000119>
<rdfs:label>BioSorter500</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400018 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400018">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400008"/>
<obo:IAO_0000111>Cell Lab Quanta SC</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A Cell Lab Quanta SC is a flow_cytometer_analyser manufactured by Becman Coulter. It features a mercury arc lamp optimized at 366, 405, and 435 nm, and a 488 nm laser diode. It has filters and PMTs to collect up to 3 fluorescent parameters, and a photodiode for side scatter detection. This cytometer uses Couter-Volume for cell size measurements. The Cell Lab Quanta SC can be used for measuring the properties of individual cells.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://www.beckmancoulter.com/cell-lab</obo:IAO_0000119>
<rdfs:label>Cell Lab Quanta SC</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400019 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400019">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000374"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000383"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>charge plate</obo:IAO_0000111>
<obo:IAO_0000112>LSR2 charge plate</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Part of the fluidics subsystem. Charge plates are used or sorters. They create an charged electric field when particles deemed to be desired for further analysis are shaken form the piexo electric crystal. The charged particles are drawn toward the charged plate, and the altered drop location causes the particles to fall into a collection tube. Charge plates enable sorting.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>Practical Flow Cytometry 4th Edition, Howard Shapiro, ISBN-10: 0471411256, ISBN-13: 978-0471411253</obo:IAO_0000119>
<rdfs:label>charge plate</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400020 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400020">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000836"/>
<obo:IAO_0000111>cell sorter collection tube</obo:IAO_0000111>
<obo:IAO_0000112>LSR2 collection tube</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Part of the fluidics subsystem. The collection tube is a vessel for capturing cells of interest that have been identified by a sorter. The collection tube is the end location of sorted cells.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>Practical Flow Cytometry 4th Edition, Howard Shapiro, ISBN-10: 0471411256, ISBN-13: 978-0471411253</obo:IAO_0000119>
<rdfs:label>cell sorter collection tube</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400022 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400022">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400008"/>
<obo:IAO_0000111>Cyan</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A Cyan is a flow_cytometer_analyser manufactured by Dako Cytomation. It features include digital electronics, three lasers: 488 nm, 635 nm, and 405 nm, and filters and collectors for nine fluorescent parameters and two scatter parameters. The Cyan can be used for measuring the properties of individual cells.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://www.dakousa.com/prod_productrelatedinformation?url=gprod_cyan_index.htm</obo:IAO_0000119>
<rdfs:label>Cyan</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400023 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400023">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400008"/>
<obo:IAO_0000111>CYFlow ML</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A CyFlow_ML is a flow_cytometer_analyser manufactured by Partec. It is a digital machine which uses 4 light sources: triple laser configurations including new powerful 200mW@488nm blue solid state laser + 100W UV lamp for highest resolution DNA analysis, and can collect 16 optical parameters: FSC1, FSC2, SSC, FL1-FL13. Ultracompact high end desktop multilaser Flow Cytometer for all applications in cell analysis and absolute counting.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://www.partec.de/products/cyflow-ml.html</obo:IAO_0000119>
<rdfs:label>CYFlow ML</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400024 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400024">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400008"/>
<obo:IAO_0000111>CyFlow SL</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">a flow_cytometer_analyser manufactured by Partec. Its specs are: ultracompact and fully equipped mobile/portable instrument, dimensions [cm]: L 43 x H 16 x D 37, highest stability/robustness and highest precision, 5 optical parameters: FSC, SSC, FL-1, FL-2, FL-3, 20mW@488nm blue solid state laser , other laser light sources optional (UV, violet, green, red), WindowsTM XP FloMax (software for real time data acquisition, data display, and data evaluation), parallel 16 bit digital pulse processing Compact mobile Flow Cytometer for any kind of cell analysis and absolute volumetric counting. The CyFlow_SL allows to analyze forward and side scatter signals in combination with up to 3 fluorescence channels.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://www.partec.de/products/cyflow.html</obo:IAO_0000119>
<rdfs:label>CyFlow SL</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400025 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400025">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400008"/>
<obo:IAO_0000111>CyFlow SL3</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A CyFlow_Sl3 is a flow_cytometer_analyser manufactured by Partec. Its specs are: ultracompact and fully equipped mobile/portable instrument, dimensions [cm]: L 43 x H 16 x D 37 , highest stability/robustness and highest precision, 5 optical parameters: FSC, SSC, FL-1, FL-2, FL-3, 20mW@488nm blue solid state laser, other laser light sources optional (UV, violet, green, red), WindowsTM XP FloMax (software for real time data acquisition, data display, and data evaluation), parallel 16 bit digital pulse processing. The CyFlow SL3 is a compact and dedicated portable Flow Cytometer for accurate and affordable cell analysis and true volumetric absolute counting in HIV Monitoring and AIDS patient follow-up by precise and direct CD4 and CD4% measurement.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://www.partec.de/products/cyflowsl3.html</obo:IAO_0000119>
<rdfs:label>CyFlow SL3</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400026 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400026">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400099"/>
<obo:IAO_0000111>CyFlow Space</obo:IAO_0000111>
<obo:IAO_0000112>CyFlow Space at TSRI Flow Cytometry Core Facility</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A CyFlow_Space is a flow_cytometer_sorter manufactured by Partec. Its specs are: 8optical parameters, 6 colours:FSC, SSC, FL1-FL6 , 3laser light sources: 200mW@488nm blue solid state laser 25mW@635nm red diode laser 50mW@405nm violet or 8mW@375nm ultraviolet diode laser _ultracompact desktop high end instrument. Parallel 16bit digital pulse processing. The CyFlow Space is a 6-Colour FCM System and Cell Sorter for Clinical Routine and Research.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://www.partec.de/products/cyflowspace.html</obo:IAO_0000119>
<rdfs:label>CyFlow Space</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400027 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400027">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400008"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
<owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/OBI_0001458"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>CytoBuoy</obo:IAO_0000111>
<obo:IAO_0000112>CytoBuoy can be used to conduct extended and/or high frequency time series of phytoplankton distribution and abundance on fixed locations</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A flow cytometer analyser which is manufactured by Cyto Buoy Inc. They are the buoy mounted version of the CytoSense, equipped with wireless transmission of control and data files. They are a single laser, multi parameter instrument. Various types of micro-laser are offered; available measuring parameters are forward light scatter, side scatter, and fluorescence (max. 9 colour bands). The current series have 5 parameters.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn, Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000119>http://www.cytobuoy.com/</obo:IAO_0000119>
<rdfs:label>CytoBuoy flow cytometer analyzer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400028 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400028">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400008"/>
<obo:IAO_0000111>CytoSence</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A CytoSense is a flow_cytometer_analyser manufactured by Cyto Buoy Inc. They are a single laser, multi parameter instrument. Various types of micro-laser are offered; available measuring parameters are forward light scatter, side scatter, and fluorescence (max. 9 colour bands). The current series have 5 parameters. The CytoSense is the basic instrument, which can be used for normal laboratory applications, as well as for autonomous monitoring with internal data logging or direct data transmission. The special instrument design and its splashproof housing allow operation on moving platforms and outdoor sites.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://www.cytobuoy.com/</obo:IAO_0000119>
<rdfs:label>CytoSence</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400029 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400029">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400008"/>
<obo:IAO_0000111>CytoSub</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A CytoSub is a flow_cytometer_analyser manufactured by Cyto Buoy Inc. They are a single laser, multi parameter instrument. Various types of micro-laser are offered; available measuring parameters are forward light scatter, side scatter, and fluorescence (max. 9 colour bands). The current series have 5 parameters. The CytoSub is the submersible version equipped with a high pressure sample inlet loop and a high pressure housing to allow underwater operation down to 200 m, lowered on a cable or mounted on a flooded underwater vehicle.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://www.cytobuoy.com/</obo:IAO_0000119>
<rdfs:label>CytoSub</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400030 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400030">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400079"/>
<obo:IAO_0000111>dichroic filter</obo:IAO_0000111>
<obo:IAO_0000112>Cy3 Dichroic Filter</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A dichroic filter is an optical filter which is used to selectively pass light of a small range of colors while reflecting other colors. A dichroic filter passes the specified range of light whereas a dichroic mirror reflects the specified range of light.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Dichroic_filter</obo:IAO_0000119>
<rdfs:label>dichroic filter</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400031 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400031">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400079"/>
<obo:IAO_0000111>dichroic mirror</obo:IAO_0000111>
<obo:IAO_0000112>ViewLux Alexa 594 dichroic mirror</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A dichroic mirror is an optical filter which is used to selectively reflect light of a small range of colors while passing other colors. A dichroic filter passes the specified range of light whereas a dichroic mirror reflects the specified range of light.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Dichroic_mirror</obo:IAO_0000119>
<rdfs:label>dichroic mirror</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400032 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400032">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>differential pressure gauge</obo:IAO_0000111>
<obo:IAO_0000112>LSR2 differential pressure gauge</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Part of the fluidics subsystem. The differential pressure gauge monitors the difference between sample and sheath fluid pressures in systems where pressure is used to force the sample fluid to flow in the center of the sheath fluid. A differential pressure gauge can be used by the operator to make sure that the sample fluid is at a greater pressure than the sheath fluid, which maintains a core of sample fluid.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>Practical Flow Cytometry 4th Edition, Howard Shapiro, ISBN-10: 0471411256, ISBN-13: 978-0471411253</obo:IAO_0000119>
<rdfs:label>differential pressure gauge</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400033 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400033">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400064"/>
<obo:IAO_0000111>diode laser</obo:IAO_0000111>
<obo:IAO_0000112>FAX-RS3-H0 diode laser manufactured by Diode Laser Concepts, Inc.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A diode laser is a laser in which the active medium is a p-n junction semiconductor laser diode, similar to that found in a light-emitting diode. Laser diodes emit at wavelengths from 375 nm to 1800 nm, and wavelengths of over 3 micrometer have been demonstrated. A diode laser can by used to irradiate cells in a flow cytometer.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>John Quinn</obo:IAO_0000119>
<rdfs:label>diode laser</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400034 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400034">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400064"/>
<obo:IAO_0000111>dye laser</obo:IAO_0000111>
<obo:IAO_0000112>Rhodamine 101 dye laser used to irradiate cells in a flow cytometer.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A dye laser is a laser in which the lasing medium is a fluorescent dye, usually dissolved in an organic solvent such as ethanol or ethylene glycol. The particular dye used determines the wavelengths the laser can emit. The laser medium is places between two parallel mirrors for light emission amplification.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>John Quinn</obo:IAO_0000119>
<obo:IAO_0000119>Practical Flow Cytometry 4th Edition, Howard Shapiro, ISBN-10: 0471411256, ISBN-13: 978-0471411253</obo:IAO_0000119>
<rdfs:label>dye laser</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400036 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400036">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400099"/>
<obo:IAO_0000111>FACS Calibur</obo:IAO_0000111>
<obo:IAO_0000112>FACS Calibur at TFL, BCCRC, Vancouver</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">The FACS Calibur is one of the most popular cytometers in use for research.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://www.bdbiosciences.com/immunocytometry_systems/products/display_product.php?keyID=45, 2007-05-11</obo:IAO_0000119>
<rdfs:label>FACS Calibur</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400037 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400037">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400008"/>
<obo:IAO_0000111>FACS Canto</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A FACS_Canto is a flow_cytometer_analyser manufactured by Becton Dickinson. It features digital electronics, a solid state 488 nm, and a HeNe 633 nm lasers, and filters and PMTs for collecting up to 6 fluorescent parameters. The FACS_Canto is an analyser usually used in clinical applications.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://www.bdbiosciences.com/pdfs/brochures/23-8742-00.pdf</obo:IAO_0000119>
<rdfs:label>FACS Canto</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400038 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400038">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400008"/>
<obo:IAO_0000111>FACS Canto2</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A FACS_Canto2 is a flow_cytometer_analyser manufactured by BD. It features digital electronics, two solid state lasers at 488 and 633 nm with the option for a third 405 nm laser, and filters and collectors for measuring up to 8 fluorescent paramters with either the 2 or 3 laser option. The FACS_Canto2 is an analyser usually used in clinical applications.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://www.bdbiosciences.com/cgi-bin/literature/view?part_num=23-8786-01</obo:IAO_0000119>
<rdfs:label>FACS Canto2</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400039 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400039">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400008"/>
<obo:IAO_0000111>FACS Scan</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A FACS_Scan is a flow_cytometer_analyser manufactured by Becton Dickinson. IT features analog electronics, one 488 nm solid state laser, and the filters and PMTs to collect up to three fluorescent parameters The FACS_Scan is usually used for research applications.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://www.brc.ubc.ca/brc/facs.html</obo:IAO_0000119>
<rdfs:label>FACS Scan</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400040 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400040">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400099"/>
<obo:IAO_0000111>FACSAria</obo:IAO_0000111>
<obo:IAO_0000112>FACSAria at TSRI Flow Cytometry Core Facility</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A FASCSAria is a flow_cytometer_sorter manufactured by Becton Dickinson. It features digital electronics, a solid state 488 nm blue laser, a solid state 407 nm violet laser, and a HeNe (633 nm) ion laser. The Aria has the filters and PMTs to collect side scatter and 9 fluorescent parameters. The Aria has a photodiode detector for forward scatter collector. The flow cell is Quartz cuvette. The FACSAria is a sorter used to collect and analyse cells using up to 11 parameters.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://www.bdbiosciences.com/external_files/is/doc/mkt_lit/brochures/SJ-0003-00Aria.pdf</obo:IAO_0000119>
<rdfs:label>FACSAria</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400041 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400041">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400099"/>
<obo:IAO_0000111>FACSvantage</obo:IAO_0000111>
<obo:IAO_0000112>FACSvantage at TSRI Flow Cytometry Core Facility</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">The FACSvantage is a flow_cytometer_sorter manufactured by Becton Dickinson. It has analog electronics, three lasers (several options are available), and the filters and PMTs to collect 6 fluorescent parameters and side scatter, and a photodiode to collect forward scatter. The FACSvantage can be used to analyse, sort and collect cells.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://www.bdbiosciences.com/features/products/display_product.php?keyID=42</obo:IAO_0000119>
<rdfs:label>FACSvantage</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400042 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400042">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400008"/>
<obo:IAO_0000111>FC 500</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A FC_500 is a flow_cytometer_analyser manufactured by Beckman Coulter. It features digital electronics, 488 nm and 635 nm lasers, filters and PMTs for 5 fluorescent parameters, a diode for collecting side scatter and a solid state detector for forward scatter. The FC 500 is an analyser usually used for either research or clinical applications.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://www.beckmancoulter.com/products/instrument/flowcytometry/fc500series.asp</obo:IAO_0000119>
<rdfs:label>FC 500</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400043 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400043">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000967"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000370"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>flow cell</obo:IAO_0000111>
<obo:IAO_0000112>Biofilm Flow Cell</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Aparatus in the fluidic subsystem where the sheath and sample meet. Can be one of several types; jet-in-air, quartz cuvette, or a hybrid of the two. The sample flows through the center of a fluid column of sheath fluid in the flow cell.</obo:IAO_0000115>
<obo:IAO_0000117>Person:John Quinn</obo:IAO_0000117>
<obo:IAO_0000118>flow_cell</obo:IAO_0000118>
<obo:IAO_0000119>http://www.flocyte.com/FRTP/Resources/flow_cytometry_glossary.htm</obo:IAO_0000119>
<rdfs:label>flow cell</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400044 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400044">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400137"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400043"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400065"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400078"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400079"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400082"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400153"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>flow cytometer</obo:IAO_0000111>
<obo:IAO_0000112>FACS Calibur</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A flow_cytometer is an instrument for counting, examining and sorting microscopic particles in suspension. It allows simultaneous multiparametric analysis of the physical and/or chemical characteristics of single cells flowing through an optical and/or electronic detection apparatus. A flow cytometer is an instrument that can be used to quantitatively measure the properties of individual cells in a flowing medium.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Flow_cytometer</obo:IAO_0000119>
<rdfs:label>flow cytometer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400045 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400045">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001034"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000401"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>fluid pressure regulator</obo:IAO_0000111>
<obo:IAO_0000112>LSR2 fluid pressure regulator</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Part of the fluidic subsystem. The fluid pressure regulator maintains constant pressure within the sheath and or sample lines by filling the lines with enough gas to push the fluid at the desired rate. The gas is usually air, and less frequently nitrogen. In the sheath line, the gas is pushed into the sheath tank. In the sample line the gas is pushed into the collection tube. Fluid pressure regulators maintain great enough pressure to push sample fluid out of the tube and sheath fluid out of the sheath tank.</obo:IAO_0000115>
<obo:IAO_0000117>Person: John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>Practical Flow Cytometry 4th Edition, Howard Shapiro, ISBN-10: 0471411256, ISBN-13: 978-0471411253</obo:IAO_0000119>
<rdfs:label>fluid pressure regulator</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400047 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400047">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400064"/>
<obo:IAO_0000111>gas laser</obo:IAO_0000111>
<obo:IAO_0000112>helium-neon gas laser used to erradiate cells in a flow cytometer.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A gas laser is a laser in which the lasing medium is a gas. The laser medium is places between two parallel mirrors for light emission amplification. The gas is excited to emit light via an external light source or an electric current discharging through the gas.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>John Quinn</obo:IAO_0000119>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Gas_laser</obo:IAO_0000119>
<rdfs:label>gas laser</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400048 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400048">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400008"/>
<obo:IAO_0000111>Guava EasyCyte Mini</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A Guava_EasyCyte_Mini is a flow_cytometer_analyser that includes a single 488 nm laser, and filters and PMTs to collect up to 3 fluorescent parameters. It includes a photodiode forward scatter collector and an optional photodiode for side scatter collection.Guava cytometers use aspiration instead of fluid systems to transport cells within the machine. The mini accepts tubes only for inputting cells or beads. The Guava_EasyCyte_Mini cytometer is a small portable cytometer particularly useful for field measurement.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://www.guavatechnologies.com/main/products/easyCyteMini.cfm</obo:IAO_0000119>
<rdfs:label>Guava EasyCyte Mini</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400049 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400049">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400008"/>
<obo:IAO_0000111>Guava EasyCyte Plus</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A Guava_EasyCyte_Plus System is a flow_cytometer_analyser that includes a single 488 nm laser, and filters and PMTs to collect up to 4 fluorescent parameters. It includes a photodiode forward scatter collector and an optional photodiode for side scatter collection.Guava cytometers use aspiration instead of fluid systems to transport cells within the machine. The EasyCyte plus accepts 96 well plates as well as tubes. The Guava_EasyCyte_Plus cytometer is a small portable cytometer particularly useful for field measurement.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://www.guavatechnologies.com/main/products/easycyte-new.cfm</obo:IAO_0000119>
<rdfs:label>Guava EasyCyte Plus</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400050 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400050">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400008"/>
<obo:IAO_0000111>Guava Personal Cell Analysis</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A Guava_Personal_Cell_Analysis System is a flow_cytometer_analyser that includes a single 532 nm laser, and filters and PMTs to collect up to 2 fluorescent parameters. It includes a photodiode forward scatter collector. Guava cytometers use aspiration instead of fluid systems to transport cells within the machine. The PCA96 uses only tubes to introduce specimen. The Guava PCA cytometer is a small portable cytometer particularly useful for field measurement.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000118>Guava_PCA</obo:IAO_0000118>
<obo:IAO_0000119>http://www.guavatechnologies.com/main/products/PCA-new.cfm</obo:IAO_0000119>
<rdfs:label>Guava Personal Cell Analysis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400051 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400051">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400008"/>
<obo:IAO_0000111>Guava Personal Cell Analysis-96</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">The Guava_Personal_Cell_Analysis-96 Systems is a flow_cytometer_analyser that includes a single 532 nm laser, and filters and PMTs to collect up to 2 fluorescent parameters. It includes a photodiode forward scatter collector. Guava cytometers use aspiration instead of fluid systems to transport cells within the machine. The PCA96 uses either tubes or 96 well plates to introduce specimen. The Guava PCA -96 cytometer is a small portable cytometer particularly useful for field measurement.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000118>Guava_PCA-96</obo:IAO_0000118>
<obo:IAO_0000119>http://www.guavatechnologies.com/main/products/PCA-96new.cfm</obo:IAO_0000119>
<rdfs:label>Guava Personal Cell Analysis-96</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400052 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400052">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400073"/>
<obo:IAO_0000111>helium cadmium ion laser</obo:IAO_0000111>
<obo:IAO_0000112>KIMMON HeCd 325nm laser</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A helium-cadmium laser is a metal vapor laser that emits wavelengths of 442, 325 and 354 nms. This laser is a metal vapor laser. A helium-cadmium laser can by used to irradiate cells in a flow cytometer.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Laser#Gas_lasers</obo:IAO_0000119>
<rdfs:label>helium cadmium ion laser</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400053 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400053">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400060"/>
<obo:IAO_0000111>helium neon ion laser</obo:IAO_0000111>
<obo:IAO_0000112>A helium neon laser can by used to irradiate cells in a flow cytometer.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A helium-neon laser (HeNe) is an ion laser that uses helium and neon gas-ions as lasing medium. HeNe lasers emit at 543 nm and 633 nm most commonly and can also be used at 543, 594, and 611 nm.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>John Quinn</obo:IAO_0000119>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Laser#Gas_lasers</obo:IAO_0000119>
<rdfs:label>helium neon ion laser</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400054 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400054">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400146"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400044"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400135"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>Amnis ImageStream</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">The ImageStream is a multispectral_imaging_flow_cytometer manufactured by Amnis. Its has digital electronics, a single standard 488 nm solid state laser. In addition an optional 658 nm and your choice of either a 405 nm or 375 nm solid state laser can be added. Information is collected using cameras. The ImageStream system CCD camera produces six images of each cell, including darkfield, brightfield, and up to four fluorescent colors. Each image is used to calculate over 40 features, so a six-image assay results in ~250 morphometric and photometric features per cell. The ImageStream is a flow cytometer that takes pictures of the cells in flow. It has both components, an Image cytometer and a flow cytometer.</obo:IAO_0000115>
<obo:IAO_0000116>It has both components, an Image cytometer and a flow cytometer.</obo:IAO_0000116>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000119>http://www.amnis.com/</obo:IAO_0000119>
<rdfs:label>Amnis ImageStream</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400055 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400055">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400008"/>
<obo:IAO_0000111>inFlux Analyzer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">The inFlux Analyzer is a flow_cytometer_analyser manufactured by Cytopeia. It is a digital machine, with these laser options: Coherent 70, 90, 300 series water cooled lasers, solid state UV 355nm, Violet 408nm, Violet-Blue 479nm, Blue-488nm, Green-531nm, Red-635nm, Red-647nm. Filters and PMTs are used for all parameters (including forward light scatter), and up to 12 PMTs can be included. The Influx analyser can be used to measure the properties of individual cells.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://www.cytopeia.com/analyzer.htm</obo:IAO_0000119>
<rdfs:label>inFlux Analyzer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400056 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400056">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400099"/>
<obo:IAO_0000111>Influx Cell Sorter</obo:IAO_0000111>
<obo:IAO_0000112>Influx Cell Sorter at TSRI Flow Cytometry Core Facility</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A Influx Cell Sorter is a flow_cytometer_sorter manufactured by Cytopeia. It is a digital machine, with these laser options: Coherent 70, 90, 300 series water cooled lasers, solid state UV 355nm, Violet 408nm, Violet-Blue 479nm, Blue-488nm, Green-531nm, Red-635nm, Red-647nm. The sorting is multi-way, index, and proportional sorting. Filters and PMTs are used for all parameters (including forward light scatter), and up to 12 PMTs can be included. The Influx cell sorter can be used to measure, sort, and collect ndividual cells.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://www.cytopeia.com/sorter.htm</obo:IAO_0000119>
<rdfs:label>Influx Cell Sorter</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400059 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400059">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000029"/>
<obo:IAO_0000111 xml:lang="en">interrogation_point</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Interrogation point in BD FACS Calibur</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Point within the fluidic subsystem at which the laser intersects the stream, illuminating the cells where they emit their fluorescence and scatter the light. The laser irradiates the cell at the interrogation point.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">John Quinn</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">http://www.flocyte.com/FRTP/Resources/flow_cytometry_glossary.htm, 2007-05-11</obo:IAO_0000119>
<rdfs:label xml:lang="en">interrogation_point</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400060 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400060">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400047"/>
<obo:IAO_0000111>ion laser</obo:IAO_0000111>
<obo:IAO_0000112>2 Watt Lexel 88 Argon Ion laser</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An ion laser is a gas laser which uses an ionized gas as its lasing medium.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>John Quinn</obo:IAO_0000119>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Ion_laser</obo:IAO_0000119>
<rdfs:label>ion laser</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400061 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400061">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000029"/>
<obo:IAO_0000111 xml:lang="en">jet_in_air_flow_chamber</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Jet-in-air flow chamber in DakoCytomation MoFlo high-speed cell sorter</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A flow cell in which the cells are pinched off as droplets and allowed to drop through the air. The laser intersects with the cell in mid-air. A jet in air flow chamber allows the laser to intersect with the cells without any intermittent media other than air.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">John Quinn</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">http://www.flocyte.com/FRTP/Resources/flow_cytometry_glossary.htm</obo:IAO_0000119>
<rdfs:label xml:lang="en">jet_in_air_flow_chamber</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400062 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400062">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400060"/>
<obo:IAO_0000111>krypton ion laser</obo:IAO_0000111>
<obo:IAO_0000112>Lexel 95L krypton laser</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A krypton-ion laser is an ion laser that uses krypton as the lasing medium. These lasers can emit at 468, 476, 482, 520, 531, 568, 647 (the most powerful line), and 676 nm all at once. They have much lower gain than argon lasers however.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>John Quinn</obo:IAO_0000119>
<rdfs:label>krypton ion laser</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400063 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400063">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400115"/>
<obo:IAO_0000111>LactoScope C4</obo:IAO_0000111>
<obo:IAO_0000112>LactoScope C4 Automatic Economical</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A LactoScope_C4 is a spectrophotometer with which the composition of milk and milk products is analysed via infrared technology. The LactoScope determines the amount of the constituents fat, protein, lactose and the total solids content with extreme accuracy.</obo:IAO_0000115>
<obo:IAO_0000117>Josef Spidlen</obo:IAO_0000117>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000119>http://www.aicompanies.com/DeltaCD/lacto_ftir_auto.htm</obo:IAO_0000119>
<rdfs:label>LactoScope C4</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400064 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400064">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400065"/>
<obo:IAO_0000111>laser</obo:IAO_0000111>
<obo:IAO_0000112>A laser is the most common way to irradiate a cell in a flow cytometer.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A laser (acronym for light amplification by the stimulated emission of radiation) is a light source that emits photons of the same characteristics in a coherent beam. A laser uses a solid, liquid or gaseous lasing medium, that contains molecules, of which some atoms have electrons that emit photons of the same frequency when falling back to their normal orbital after excitation (pumping) by external means A laser is the most common way to irradiate a cell in a flow cytometer.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000118>light amplification by the stimulated emission of radiation</obo:IAO_0000118>
<obo:IAO_0000119>John Quinn</obo:IAO_0000119>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Laser</obo:IAO_0000119>
<rdfs:label>laser</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400065 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400065">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001032"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000367"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>light source</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A light source is an optical subsystem that provides light for use in a distant area using a delivery system (e.g., fiber optics). Light sources may include one of a variety of lamps (e.g., xenon, halogen, mercury). Most light sources are operated from line power, but some may be powered from batteries. They are mostly used in endoscopic, microscopic, and other examination and/or in surgical procedures. The light source is part of the optical subsystem. In a flow cytometer the light source directs high intensity light at particles at the interrogation point. The light source in a flow cytometer is usually a laser.</obo:IAO_0000115>
<obo:IAO_0000117>Elizabeth M. Goralczyk</obo:IAO_0000117>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000117>Olga Tchuvatkina</obo:IAO_0000117>
<obo:IAO_0000119>Practical Flow Cytometry 4th Edition, Howard Shapiro, ISBN-10: 0471411256, ISBN-13: 978-0471411253</obo:IAO_0000119>
<rdfs:label>light source</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400066 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400066">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400101"/>
<obo:IAO_0000111>logarithmic voltage amplifier</obo:IAO_0000111>
<obo:IAO_0000112>HLVA-100 logarithmic voltage amplifier developed by FEMTO Messtechnik, GmbH</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A logarithmic voltage amplifier is an analog electronic circuit that puts out a voltage or current proportional to the voltage or current at its input, with logarithmic proportionality. In an analog system, the logarithmic voltage amplifier is used to present parameters with a high dynamic range on a more useful scale.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>Practical Flow Cytometry 4th Edition, Howard Shapiro, ISBN-10: 0471411256, ISBN-13: 978-0471411253</obo:IAO_0000119>
<rdfs:label>logarithmic voltage amplifier</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400067 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400067">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400079"/>
<obo:IAO_0000111>long pass filter</obo:IAO_0000111>
<obo:IAO_0000112>750 LP filter</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A long pass filter is an optical filter that passes high wavelengths of light but attenuates (or reduces) wavelengths lower than the cutoff frequency. A long pass filter with a cutoff of 500 nm would pass all wavelengths greater than 500 nm.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/high-pass_filter</obo:IAO_0000119>
<rdfs:label>long pass filter</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400068 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400068">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400099"/>
<obo:IAO_0000111>LSR2</obo:IAO_0000111>
<obo:IAO_0000112>LSR2 at TSRI Flow Cytometry Core Facility</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A LSR2 is a sorter manufactured by Becton Dickinson. It features digital electronics, a solid state 488 nm blue laser and optionally can also have any combination of solid state UV (355 nm) and violet (405 nm) lasers and the a HeNe (633 nm) ion laser. The LSR2 has the filters and PMTs to work with 13 fluorescent parameters. The LSR II is one of the most common sorters in use.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://www.bdbiosciences.com/external_files/is/doc/mkt_lit/brochures/live/web_enabled/SJ-0142-00LSR2.pdf</obo:IAO_0000119>
<rdfs:label>LSR2</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400069 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400069">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400008"/>
<obo:IAO_0000111>Luminex 100</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">The Luminex 100 is a flow_cytometer_analyser manufactured by Luminex. It is a single laser system (575 nm) with avalanche photodiodes in red and infrared and a single PMT for fluorescence. The flow chamber is a square quartz cuvette.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://www.luminexcorp.com/products/luminex_100IS.html</obo:IAO_0000119>
<rdfs:label>Luminex 100</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400070 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400070">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400008"/>
<obo:IAO_0000111>Luminex 200</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A Luminex_200 is a flow_cytometer_analyser manufactured by Luminex. The optical specifications are: Reporter laser: 532 nm, nominal output 10 - 15 mW, maximum 500 mW, frequency-doubled diode; mode of operation, continuous wave (CW). Classification laser: 635 nm, 9.1 __ 6%, maximum output 25 mW, diode; mode of operation, continuous wave (CW) Reporter detector: Photomultiplier tube, detection bandwidth of 565 - 585 nm Classification detector and doublet discriminator: Avalanche photo diodes with temperature compensation</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://www.luminexcorp.com/support/faqs.html</obo:IAO_0000119>
<rdfs:label>Luminex 200</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400071 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400071">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400008"/>
<obo:IAO_0000111>MACS Quant</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A MACS Quant is a flow_cytometer_analyser manufactured by Miltenyi. It uses digital electronics, and has three lasers of wavelengths 405 nm, 488 nm, and 635 nm. It has filters and detectors to collect 7 fluorescent parameters and 2 scatter parameters. The MACS Quant is an analyser usually used in research applications.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://www.miltenyi.com</obo:IAO_0000119>
<rdfs:label>MACS Quant</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400073 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400073">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400047"/>
<obo:IAO_0000111>metal vapor laser</obo:IAO_0000111>
<obo:IAO_0000112>Gold vapor laser, Helium-cadmium metal-vapor laser</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A metal vapor laser is a gas laser in which the lasing medium is metal vapor. A metal vapor laser can by used to irradiate cells in a flow cytometer.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>Practical Flow Cytometry 4th Edition, Howard Shapiro, ISBN-10: 0471411256, ISBN-13: 978-0471411253</obo:IAO_0000119>
<rdfs:label>metal vapor laser</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400074 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400074">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400060"/>
<obo:IAO_0000111>mixed argon-krypton gas laser</obo:IAO_0000111>
<obo:IAO_0000112>argon-krypton laser in a cytometer</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A mixed argon krypton gas laser is an ion laser in which the lasing medium is a mixture of argon and krypton. A mixed argon-krypton laser can by used to irradiate cells in a flow cytometer.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://www.eio.com/repairfaq/sam/laserarg.htm</obo:IAO_0000119>
<rdfs:label>mixed argon-krypton gas laser</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400075 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400075">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400099"/>
<obo:IAO_0000111>MoFlo</obo:IAO_0000111>
<obo:IAO_0000112>MoFlo at TSRI Flow Cytometry Core Facility</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A MoFlo is a flow_cytometer_sorter manufactured by Dako Cytomation. It features digital electronics, the option to include several lasers (solid state 488 nm, 635 nm, and a 351 nm diode laser), and has the filtering and collection capacity for up to 10 flouresecent parameters. The MoFlo is an instrument that can be used to both analyze quantitatively and collect cells in a flowing medium.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://www.dakousa.com/index/prod_search/prod_groups.htm?productareaid=16</obo:IAO_0000119>
<rdfs:label>MoFlo</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400076 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400076">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400081"/>
<obo:IAO_0000111 xml:lang="en">multi-well plate</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">96 well plate, 48 multiwell plate</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A particle deliver vessel. A multi-well plate is a vessel that can deliver multiple samples to a flow cytometer in a specified order. It must be used with a plate loader.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">FG this is synonymous with microtiter plate</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">John Quinn</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">http://www.nuncbrand.com/page.aspx?ID=301</obo:IAO_0000119>
<rdfs:label xml:lang="en">multi-well plate</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400077 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400077">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400096"/>
<obo:IAO_0000111>neodymium-YAG laser</obo:IAO_0000111>
<obo:IAO_0000112>Neodymium-YAG Laser in DURIP99 System</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A Neodymium-YAG (yttrium aluminum garnet) laser is a solid state laser in which the lasing medium is a solid rod of crystalline material pumped by a flash lamp or a diode laser. Typical output wavelengths are 355, 532, and 1064 nm. A neodymium-YAG laser can by used to irradiate cells in a flow cytometer.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>John Quinn</obo:IAO_0000119>
<rdfs:label>neodymium-YAG laser</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400078 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400078">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000932"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000378"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>obscuration bar</obo:IAO_0000111>
<obo:IAO_0000112>obscuration bar in a flow cytometer</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An obscuration bar is a an optical subsystem which is a strip of metal or other material that serves to block out direct light from the illuminating beam. The obscuration bar prevents the bright light scattered in the forward directions from burning out the collection device.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>Flow Cytometry: First Principles, by Alice Longobardi Givan, ISBN-10: 0471382248, ISBN-13: 978-0471382249</obo:IAO_0000119>
<obo:IAO_0000119>John Quinn</obo:IAO_0000119>
<rdfs:label>obscuration bar</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400079 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400079">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000932"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000378"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>optical filter</obo:IAO_0000111>
<obo:IAO_0000112>720 LP filter, 580/30 BP filter</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An optical filter is an optical subsystem that selectively transmits light having certain properties (often, a particular range of wavelengths, that is, range of colours of light), while blocking the remainder. They are commonly used in photography, in many optical instruments, and to colour stage lighting Optical filters can be arranged to segregate and collect light by wave length.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Optical_filter</obo:IAO_0000119>
<rdfs:label>optical filter</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400080 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400080">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400065"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400078"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400079"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>optical subsystem</obo:IAO_0000111>
<obo:IAO_0000112>optical subsystem of a cytometer</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A device or part of a device that deals with the behavior and properties of light and the interaction of light with matter. Commonly optical subsystems consist of an excitation optics and collection optics. The excitation optics of a flow cytometer optical subsystem consist of the laser and lenses that are used to shape and focus the laser beam. The collections optics consist of a collection lens to collect light emitted from the particle laser beam interaction and a system of optical mirrors and filters to route specified wavelengths of the collected light to designated optical detectors. The optical subsystem in a flow cytometer consists of the equipment used to irradiate particles, and collect the light either emitted or scattered by those particles.</obo:IAO_0000115>
<obo:IAO_0000116>DS: Is 'subsystem' necessary or is 'optical_system' enough. Not sure its graph position since an optical subsystem is not necessarily an instrument, but more likely part of one.</obo:IAO_0000116>
<obo:IAO_0000117>Person: Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>John Quinn</obo:IAO_0000119>
<rdfs:label>optical subsystem</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400081 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400081">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<obo:IAO_0000111 xml:lang="en">particle delivery vessel</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">FC 500 particle delivery vessel</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Part of the fluidics subsystem. A particle delivery vessel is used to introduce either a single sample or multiple samples to a flow cytometer. The most common particle delivery vessel is a sample tube.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">John Quinn</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">Practical Flow Cytometry 4th Edition, Howard Shapiro, ISBN-10: 0471411256, ISBN-13: 978-0471411253</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">FG: this should be delted - particle delivery is a role that an object can play</obo:IAO_0000232>
<rdfs:label xml:lang="en">particle delivery vessel</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400082 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400082">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>photodetector</obo:IAO_0000111>
<obo:IAO_0000112>A photomultiplier tube, a photo diode</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A photodetector is a device used to detect and measure the intensity of radiant energy through photoelectric action. In a cytometer, photodetectors measure either the number of photons of laser light scattered on impact with a cell (for example), or the flourescence emitted by excitation of a fluorescent dye.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://einstein.stanford.edu/content/glossary/glossary.html</obo:IAO_0000119>
<rdfs:label>photodetector</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400083 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400083">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400082"/>
<obo:IAO_0000111>photodiode</obo:IAO_0000111>
<obo:IAO_0000112>Avalanche photodiode</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A photodiode is a semiconductor photodetector used to detect light and generate an electrical current. Typically used in forward scatter (FSC) detection. The photodiode collects the forward light scatter in a cytometer.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://cyto.mednet.ucla.edu/Protocols/flow.htm</obo:IAO_0000119>
<rdfs:label>photodiode</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400084 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400084">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000967"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000370"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000395"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>photomultiplier tube</obo:IAO_0000111>
<obo:IAO_0000112>R9647 by manufactured by Hamamatsu</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A photomultiplier is a device that is normally in the form of a tube, that uses a photocathode to convert photons into photoelectrons which are then amplified. PMTs are typically used to detect SSC and fluorescent parameters. Cytometers have a PMT for each color they can collect.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://cyto.mednet.ucla.edu/Protocols/flow.htm</obo:IAO_0000119>
<rdfs:label>photomultiplier tube</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400085 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400085">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000377"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>piezo electric crystal</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">quartz piezoelectric crystal, topaz piezoelectric crystal, piezoelectric crystal in a sonar</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Apparatus in the fluidic subsystem of sorters that vibrates to break up the stream coming out of the flow chamber into droplets for sorting. The peizo electric crystal vibrates in a manner that breaks off droplets at regular intervals. Not all droplets contain a cell.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">John Quinn</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">http://www.flocyte.com/FRTP/Resources/flow_cytometry_glossary.htm</obo:IAO_0000119>
<obo:IAO_0000232>think this is natural thing, not a device HP/JF</obo:IAO_0000232>
<rdfs:label xml:lang="en">piezo electric crystal</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400086 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400086">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000383"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>plate loader</obo:IAO_0000111>
<obo:IAO_0000112>FC 500 plate loader</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Part of the fluidics system. A plate loader positions the wells of a multi-well plate under the aspiration tube is a preset order. A plate loader is used for high throughput applications.</obo:IAO_0000115>
<obo:IAO_0000116>measurement function is not corret as discussed on April 26 dev call. Will add new function such as positioning function. Add to tracker will discuss in the future.</obo:IAO_0000116>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://www.beckmancoulter.com/literature/Bioresearch/P-10202A.pdf</obo:IAO_0000119>
<rdfs:label>plate loader</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400087 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400087">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400101"/>
<obo:IAO_0000111>preamplifier</obo:IAO_0000111>
<obo:IAO_0000112>Built in preamplifier in a Hamamatsu H9656 PMT</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A preamplifier is part of the electronics subsystem. It converts the current output from its associated detector to a voltage. The preamplifier is the first stage in analog electronics signal processing.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>Practical Flow Cytometry 4th Edition, Howard Shapiro, ISBN-10: 0471411256, ISBN-13: 978-0471411253</obo:IAO_0000119>
<rdfs:label>preamplifier</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400088 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400088">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400043"/>
<obo:IAO_0000111>quartz cuvette flow chamber</obo:IAO_0000111>
<obo:IAO_0000112>CVF-Q-10 flow chamber, CV-Q-10 flow chamber</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A flow cell in which the laser irradiates the cell as it passes through a quartz cuvette. A quartz cuvette flow chamber can be used to allow the laser to irradiate cells.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://www.flocyte.com/FRTP/Resources/flow_cytometry_glossary.htm</obo:IAO_0000119>
<rdfs:label>quartz cuvette flow chamber</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400089 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400089">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400099"/>
<obo:IAO_0000111>Reflection</obo:IAO_0000111>
<obo:IAO_0000112>Reflection at TSRI Flow Cytometry Core Facility</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A Reflection is a sorter manufactured by iCyte. It uses digital signal processing, and can be configured with lasers of the users choice from among these excitation wavelengths: 355, 405,488, 532, 635nm. It accommodates up to 48 traditional PMTs. Options include an acousto-optical tunable filter (AOTF) and 16 channel spectrometer (370 to 730 nm). The various detection components can be uniquely configured across multiple Highly Automated Parallel Sorting (HAPS) modules. The Reflection can be used to analyse, sort, and collect cells.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://www.i-cyt.com/reflection.htm</obo:IAO_0000119>
<rdfs:label>Reflection</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400091 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400091">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000836"/>
<obo:IAO_0000111>cytometer sample tube</obo:IAO_0000111>
<obo:IAO_0000112>sample tube in a cytometer</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A particle delivery vessel. The cytometer sample tube is a vessel in which the sample is introduced to the cytometer. Frequently the tube is placed on the cytometer in such a manner that a seal is formed between the tube and cytometer, and gas is used to create enough pressure to push the sample out of the tube and into the cytometer.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>Practical Flow Cytometry 4th Edition, Howard Shapiro, ISBN-10: 0471411256, ISBN-13: 978-0471411253</obo:IAO_0000119>
<rdfs:label>cytometer sample tube</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400094 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400094">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002089"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000370"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000401"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>sheath tank</obo:IAO_0000111>
<obo:IAO_0000112>LSR2 sheath tank</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Part of the fluidics system. The sheath tank is the vessel that holds the sheath fluid at a constant pressure, allowing for it to be pushed into the flow chamber at a constant rate. The sheath tank holds the pressurized sheath fluid.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>Practical Flow Cytometry 4th Edition, Howard Shapiro, ISBN-10: 0471411256, ISBN-13: 978-0471411253</obo:IAO_0000119>
<rdfs:label>sheath tank</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400095 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400095">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400079"/>
<obo:IAO_0000111>short pass filter</obo:IAO_0000111>
<obo:IAO_0000112>620 SP filter</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A short pass filter is an optical filter that passes low wavelengths of light but attenuates (or reduces) wavelengths higher than the cutoff frequency. A short pass filter with a cutoff of 500 nm would pass all wavelengths less than 500 nm.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Low-pass_filter</obo:IAO_0000119>
<rdfs:label>short pass filter</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400096 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400096">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400064"/>
<obo:IAO_0000111>solid state laser</obo:IAO_0000111>
<obo:IAO_0000112>Solid State Heat Capacity Laser developed at DOE's Lawrence Livermore National Laboratory for the USA Army's Space and Missile Defense Command</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A solid-state laser is a laser that uses a lasing medium that is a solid, rather than a liquid such as dye lasers or a gas such as gas lasers. Semiconductor-based diode lasers are also in the solid state, but are generally considered separately from solid-state lasers. The first laser developed was an optical pumped ruby crystal solid state laser.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Solid-state_laser</obo:IAO_0000119>
<rdfs:label>solid state laser</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400097 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400097">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400008"/>
<obo:IAO_0000111>Somacount</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A Somacount is a flow_cytometer_analyser manufactured by Bently Instruments. It is a specialized tool for counting somatic cells in milk by specifically staining them with Ethidium Bromide and counting the cells that fluoresce. It has one laser, and the filters and a PMT for the single parameter. There are three sizes available, the 150, 300, and 500 with the number indicating the maximum number of cells that can be analysed per hour. The Somacount is an example of a very specific use cytometer; it exclusively counts somatic cells in milk.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://www.bentleyinstruments.com/somacount.html#Anchor-Bentley-49575</obo:IAO_0000119>
<rdfs:label>Somacount</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400098 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400098">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400008"/>
<obo:IAO_0000111>SomaScope</obo:IAO_0000111>
<obo:IAO_0000112>SomaScope Mark II Automatic Economical</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">The SomaScope is an instrument to quantify somatic cells in milk.</obo:IAO_0000115>
<obo:IAO_0000117>Josef Spidlen</obo:IAO_0000117>
<obo:IAO_0000119>http://www.aicompanies.com/DeltaCD/soma_auto_adv.htm, 2007-05-10</obo:IAO_0000119>
<rdfs:label>SomaScope</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400099 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400099">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000932"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400044"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400065"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400079"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400082"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400153"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000372"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>flow cytometer sorter</obo:IAO_0000111>
<obo:IAO_0000112>BioSorter2000, LSR2</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A flow_cytometer_sorter is a flow_cytometer that analyzes and separates or sorts particles passing through (based on properties measured during analysis) to collect cells of interest.</obo:IAO_0000115>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000119>http://www.flocyte.com/FRTP/Resources/flow_cytometry_glossary.htm</obo:IAO_0000119>
<rdfs:label>flow cytometer sorter</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400100 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400100">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000967"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000370"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000383"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>syringe pump</obo:IAO_0000111>
<obo:IAO_0000112>NE-1000 Single Syringe Pump</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Part of the fluidics system. A syringe pump can be used to inject the sample fluid and cells into the sheath fluid in the flow chamber. Syringe pumps are useful for creating stable flow rates.</obo:IAO_0000115>
<obo:IAO_0000117>Person:John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://www.answers.com/topic/syringe, 2007-05-11</obo:IAO_0000119>
<rdfs:label>syringe pump</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400101 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400101">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000395"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>voltage amplifier</obo:IAO_0000111>
<obo:IAO_0000112>Linear amplifier, log amplifier, microwave amplifier</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A voltage amplifier is a device that amplifies the voltage signal.</obo:IAO_0000115>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000117>John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wiktionary.org/wiki/amplifier</obo:IAO_0000119>
<rdfs:label>voltage amplifier</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400102 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400102">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000967"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000370"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>waste tank</obo:IAO_0000111>
<obo:IAO_0000112>LSR2 waste tank</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Part of the fluidics systems. In analyzers the sheath and sample fluid, once analyzed is dumped into a waste tank. The waste tank is where the fluids passing through the cytometer end up after the analysis is finished.</obo:IAO_0000115>
<obo:IAO_0000117>Person:John Quinn</obo:IAO_0000117>
<obo:IAO_0000119>Practical Flow Cytometry 4th Edition, Howard Shapiro, ISBN-10: 0471411256, ISBN-13: 978-0471411253</obo:IAO_0000119>
<rdfs:label>waste tank</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400103 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400103">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>DNA sequencer</obo:IAO_0000111>
<obo:IAO_0000112>ABI 377 DNA Sequencer, ABI 310 DNA Sequencer</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A DNA sequencer is an instrument that determines the order of deoxynucleotides in deoxyribonucleic acid sequences.</obo:IAO_0000115>
<obo:IAO_0000117>Trish Whetzel</obo:IAO_0000117>
<obo:IAO_0000119>MO</obo:IAO_0000119>
<rdfs:label>DNA sequencer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400104 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400104">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000398"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000397"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>array scanner</obo:IAO_0000111>
<obo:IAO_0000112>GenePix 4200A, GenePix4000B</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An processed material which acquires images of fluorescence (induced with lasers) from labeled molecules on the surface of the microarray chip</obo:IAO_0000115>
<obo:IAO_0000117>Trish Whetzel</obo:IAO_0000117>
<obo:IAO_0000119>GROUP: MGED Ontology</obo:IAO_0000119>
<rdfs:label>array scanner</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400105 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400105">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000383"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>arrayer</obo:IAO_0000111>
<obo:IAO_0000112>BioRobotics Microgrid II TAS, Affymetrix GMS 417</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device which deposits biological material onto a substrate in a defined pattern.</obo:IAO_0000115>
<obo:IAO_0000117>Trish Whetzel</obo:IAO_0000117>
<obo:IAO_0000119>MO_697 arrayer</obo:IAO_0000119>
<rdfs:label>arrayer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400106 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400106">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000932"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000370"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000372"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0302886"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>centrifuge</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A device with a rapidly rotating container that applies centrifugal force to its contents</obo:IAO_0000115>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000117>Person: Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000117>Trish Whetzel</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Centrifuge</obo:IAO_0000119>
<rdfs:label>centrifuge</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400107 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400107">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000392"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>computer</obo:IAO_0000111>
<obo:IAO_0000112>Apple PowerBook, Dell OptiPlex</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A computer is an instrument which manipulates (stores, retrieves, and processes) data according to a list of instructions.</obo:IAO_0000115>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000117>Trish Whetzel</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Computer</obo:IAO_0000119>
<rdfs:label>computer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400108 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400108">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001034"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000371"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>heating block</obo:IAO_0000111>
<obo:IAO_0000112>An instrument used to heat and/or maintain material at a set temperature.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A heating block is an instrument or part of an instrument which raises or maintains the temperature of a sample to a defined constant temperature during certain parts of an assay</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>MO</obo:IAO_0000119>
<rdfs:label>heating block</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400109 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400109">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001033"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000377"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>homogenizer</obo:IAO_0000111>
<obo:IAO_0000112>mortar, blender</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A homogenizer is an instrument for the homogenization of various types of material, such as tissue, plant, food, soil, and many others.</obo:IAO_0000115>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000117>Trish Whetzel</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Homogenizer</obo:IAO_0000119>
<rdfs:label>homogenizer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400110 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400110">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002089"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000370"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000401"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>hybridization chamber</obo:IAO_0000111>
<obo:IAO_0000112>Glass Array Hybridization Cassette</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device which is used to maintain constant contact of a liquid on an array. This can be either a glass vial or slide.</obo:IAO_0000115>
<obo:IAO_0000117>Trish Whetzel</obo:IAO_0000117>
<obo:IAO_0000119>MO_563 hybridization_chamber</obo:IAO_0000119>
<rdfs:label>hybridization chamber</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400111 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400111">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001034"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400110"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000401"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>hybridization station</obo:IAO_0000111>
<obo:IAO_0000112>Labnet Problot12</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device which is used to maintain the temperature of one or more hybridization_chamber(s) at a defined, constant temperature.</obo:IAO_0000115>
<obo:IAO_0000117>Trish Whetzel</obo:IAO_0000117>
<obo:IAO_0000119>MO_497 hybridization station</obo:IAO_0000119>
<rdfs:label>hybridization station</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400112 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400112">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000383"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>liquid handler</obo:IAO_0000111>
<obo:IAO_0000112>Beckman BioMek 2000</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A device that is used for automated liquid transfer and handling.</obo:IAO_0000115>
<obo:IAO_0000118>liquid_handling_instrument</obo:IAO_0000118>
<obo:IAO_0000119>MO_868 liquid_handler</obo:IAO_0000119>
<obo:IAO_0000232>DS: Is this class justified? Its a unnamed class. If so, put a fluidic_system and the fluidic_subsystem as subclasses. TW: This is required by MO. FG & DS: Capture as function. All: Needs to be reviewed, according to query use case. If we keep it its kept as unnamed owl class. The liquid handling class remains but as an undefined class with are unlikely to have children. It is expected that the reasoner would classifiy appropriate classes under this class that meet the have the liquid_handling function relation.</obo:IAO_0000232>
<obo:IAO_0000232>DS: Is this class justified? Its a unnamed class. If so, put a fluidic_system and the fluidic_subsystem as subclasses. TW: This is required by MO. FG: Or as function.</obo:IAO_0000232>
<rdfs:label>liquid handler</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400113 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400113">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001034"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000376"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000401"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>oligonucleotide synthesizer</obo:IAO_0000111>
<obo:IAO_0000112>Automated Multiplex Oligonucleotide Synthesizer</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An instrument used to chemically synthesize oligonucleotides.</obo:IAO_0000115>
<obo:IAO_0000117>Trish Whetzel</obo:IAO_0000117>
<obo:IAO_0000119>MO</obo:IAO_0000119>
<rdfs:label>oligonucleotide synthesizer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400114 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400114">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001033"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000377"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>sonicator</obo:IAO_0000111>
<obo:IAO_0000112>Sonicator 3000</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A device that converts a variable electrical current to mechanical vibration of a metallic probe. The device is used for the lysis of cells, the mixing of compounds or solutions, to framgent molecules of DNA, or to create emulsions.</obo:IAO_0000115>
<obo:IAO_0000117>Trish Whetzel</obo:IAO_0000117>
<obo:IAO_0000119>MO</obo:IAO_0000119>
<rdfs:label>sonicator</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400115 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400115">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>spectrophotometer</obo:IAO_0000111>
<obo:IAO_0000112>Helios Gamma Spectrophotometer</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A spectrophotometer is an instrument that measures the intensity of light as a function of the color, or more specifically, the wavelength of light, transmitted by a substance.</obo:IAO_0000115>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000117>Trish Whetzel</obo:IAO_0000117>
<obo:IAO_0000119>MO</obo:IAO_0000119>
<rdfs:label>spectrophotometer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400116 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400116">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002089"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000370"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000401"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>thermal cycler</obo:IAO_0000111>
<obo:IAO_0000112>Piko(tm) 96-well Thermal Cycler</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An instrument that is capable of repeatedly altering and maintaining specific temperatures for defined periods of time.</obo:IAO_0000115>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000117>Trish Whetzel</obo:IAO_0000117>
<obo:IAO_0000118>DNA_amplifier</obo:IAO_0000118>
<obo:IAO_0000118>PCR_machine</obo:IAO_0000118>
<obo:IAO_0000118>Polymerase_Chain_Reaction_ machine</obo:IAO_0000118>
<obo:IAO_0000118>thermocycler</obo:IAO_0000118>
<obo:IAO_0000119>MO</obo:IAO_0000119>
<rdfs:label>thermal cycler</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400117 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400117">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002089"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000370"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000383"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000401"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>vacuum dryer</obo:IAO_0000111>
<obo:IAO_0000112>Model 777 Microarray Oven</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An instrument which removes liquid by the application of negative pressure, i.e. vacuum.</obo:IAO_0000115>
<obo:IAO_0000117>Trish Whetzel</obo:IAO_0000117>
<obo:IAO_0000119>MO</obo:IAO_0000119>
<rdfs:label>vacuum dryer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400118 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400118">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001033"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000377"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>vortexer</obo:IAO_0000111>
<obo:IAO_0000112>VWR Genie 2</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A vortexer is an instrument that mixes small vials of liquid by creating a rotation of the liquid around its own center. It consists of an electric motor with the drive shaft oriented vertically and attached to a cupped rubber piece mounted slightly off-center. As the motor runs the rubber piece oscillates rapidly in a circular motion. When a test tube or other appropriate container is pressed into the rubber cup (or touched to its edge) the motion is transmitted to the liquid inside and a vortex is created.</obo:IAO_0000115>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000117>Trish Whetzel</obo:IAO_0000117>
<obo:IAO_0000118>vortex_mixer</obo:IAO_0000118>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Vortex_mixer</obo:IAO_0000119>
<rdfs:label>vortexer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400119 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400119">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001034"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000401"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>microarray wash station</obo:IAO_0000111>
<obo:IAO_0000112>ArrayIt(r) Microarray Wash Station</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A device that is used to wash Affymetrix-type arrays.</obo:IAO_0000115>
<obo:IAO_0000117>Trish Whetzel</obo:IAO_0000117>
<obo:IAO_0000119>MO_626 wash_station</obo:IAO_0000119>
<rdfs:label>microarray wash station</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400120 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400120">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002089"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000370"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000401"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>temperature control bath</obo:IAO_0000111>
<obo:IAO_0000112>VWR Signature Deep-Chamber Heated Water Bath. A water bath is used for temperatures up to 100 degrees C. An oil bath is employed for temperatures over 100 degrees C.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A temperature_control_bath is a device that has the function to regulate the temperature of a material, the function to contain fluid and the function to vary and maintain the temperature of the contained fluid. Heat exchange (energy transfer) between the material and the heating element is facilitated via the contained fluid. A temperature_control_bath is composed of a container, a heating element and/or a cooling element and a means to adjust the needed temperature. In most cases also a timer and a means to stir the fluid is provided as well.</obo:IAO_0000115>
<obo:IAO_0000117>Alan Ruttenburg</obo:IAO_0000117>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000119>OBI Instrument branch</obo:IAO_0000119>
<obo:IAO_0000232>DS: This was heated_bath. It was renamed to reflect the possability that the same bath can be used for cooling. We can now define the temperature variables and based on that infer if it is a cooling device or a heating device (also quite relative to surrounding temperature).</obo:IAO_0000232>
<rdfs:label>temperature control bath</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400121 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400121">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001032"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001034"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000367"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000401"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>molecular crosslinker</obo:IAO_0000111>
<obo:IAO_0000112>Stratalinker</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A device that is able to chemically join two or more molecules.</obo:IAO_0000115>
<obo:IAO_0000116>AL: if we intend that other ontologies can be used in conjunction with OBI, we shouldn't have such a general term used specifically for chemically joining two or more molecules. I'm sure there are other "crosslinkers" that are on a much different scale in engineering etc. I have moved the original label to be an alternative term, and have renamed the main label accordingly.</obo:IAO_0000116>
<obo:IAO_0000117>Trish Whetzel</obo:IAO_0000117>
<obo:IAO_0000118>molecular crosslinker</obo:IAO_0000118>
<obo:IAO_0000119>MO ?? cannot be found in MO</obo:IAO_0000119>
<rdfs:label>molecular crosslinker</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400135 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400135">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000398"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400065"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400079"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400082"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000397"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>image cytometer</obo:IAO_0000111>
<obo:IAO_0000112>The most common current application of image cytometry is for DNA analysis, followed by quantitation of immunohistochemical staining.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An image_cytometer is an instrument for image-based study or measurement of cells.</obo:IAO_0000115>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000119>http://web.mit.edu/solab/Research/ImageCytometry.html</obo:IAO_0000119>
<rdfs:label>image cytometer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400137 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400137">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000832"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400065"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400079"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400082"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000453"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>cytometer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A cytometer is an instrument for counting and/or measuring characteristics of cells.</obo:IAO_0000115>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000119>http://medical.merriam-webster.com/medical/cytometer</obo:IAO_0000119>
<rdfs:label>cytometer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400140 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400140">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002089"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000370"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000401"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>gel tank</obo:IAO_0000111>
<obo:IAO_0000112>CHEF gel box, slab gel box, capillary electrophoresis</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A device which holds a gel and running buffers to allow electrophoresis to be performed. A gel tank has the function to contain and to control the contained environment and transfer energy from an energy supply through the running buffers to the gel matrix and the material with charged molecules in an electric field across a porous matrix or medium with the objective to separate the charged molecules.</obo:IAO_0000115>
<obo:IAO_0000117>Person:Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000117>Person:Kevin Clancy</obo:IAO_0000117>
<obo:IAO_0000118>electrophoresis box</obo:IAO_0000118>
<obo:IAO_0000118>electrophoresis unit</obo:IAO_0000118>
<obo:IAO_0000119>sep:00095</obo:IAO_0000119>
<rdfs:label>gel tank</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400142 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400142">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000384"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>power supply</obo:IAO_0000111>
<obo:IAO_0000112>A AC/DC transformer that generates the reqired power for an electrophoresis apparatus</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A power supply is an device or part of a device that permits the required application of a defined electrical charge to an instrument. The power supply may permit the defined application of a given amount of current for a defined length of time.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000118>PSU</obo:IAO_0000118>
<obo:IAO_0000118>electrical power supply</obo:IAO_0000118>
<obo:IAO_0000118>power pack</obo:IAO_0000118>
<obo:IAO_0000118>power supply unit</obo:IAO_0000118>
<obo:IAO_0000119>PERSON: Daniel Schober</obo:IAO_0000119>
<obo:IAO_0000119>sep:00093</obo:IAO_0000119>
<obo:IAO_0000232>was power_pack, maps to SEP electrical_power_supply</obo:IAO_0000232>
<rdfs:label>power supply</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400143 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400143">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400115"/>
<obo:IAO_0000111>fluorometer</obo:IAO_0000111>
<obo:IAO_0000112>laser/detector in capillary electrophoresis apparatus, NanoDrop ND-3300</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A fluorometer is an instrument for the detection and measurement of parameters of fluoresence, which in turn are used to identify the presence and amount of specific molecules in the sample.</obo:IAO_0000115>
<obo:IAO_0000117>Allyson Lister</obo:IAO_0000117>
<obo:IAO_0000117>Kevin Lister</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<rdfs:label>fluorometer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400146 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400146">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000398"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400044"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000392"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000397"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>multispectral imaging flow cytometer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A multispectral_imaging_flow_cytometer is an instrument which combines quantitative image analysis and flow cytometry in a single platform. It measures the amount, location and movement of molecules on, in, or between cells, and the location and co-localization of multiple markers on or in cells. It can also quantitate morphologically distinct cell subpopulations.</obo:IAO_0000115>
<obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000118>MIFC</obo:IAO_0000118>
<obo:IAO_0000119>http://www.amnis.com/</obo:IAO_0000119>
<rdfs:label>multispectral imaging flow cytometer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400147 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400147">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001865"/>
<obo:IAO_0000111>microarray</obo:IAO_0000111>
<obo:IAO_0000112>An affymetrix U133 array is a microarray. Microarrays include 1 and 2-color arrays, custom and commercial arrays (e.g, Affymetrix, Agilent, Nimblegen, Illumina, etc.) for expression profiling, DNA variant detection, protein binding, and other genomic and functional genomic assays.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A processed material that is made to be used in an analyte assay. It consists of a physical immobilisation matrix in which substances that bind the analyte are placed in regular spatial position.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Chris Stoeckert</obo:IAO_0000119>
<rdfs:label>microarray</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400148 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400148">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400147"/>
<obo:IAO_0000111>DNA microarray</obo:IAO_0000111>
<obo:IAO_0000112>Moran G, Stokes C, Thewes S, Hube B, Coleman DC, Sullivan D (2004). "Comparative genomics using Candida albicans DNA microarrays reveals absence and divergence of virulence-associated genes in Candida dubliniensis". Microbiology 150: 3363-3382. doi:10.1099/mic.0.27221-0. PMID 15470115</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A DNA-microarray is a microarray that is used as a physical 2D immobilisation matrix for DNA sequences. DNA microarray-bound DNA fragments are used as targets for a hybridising probed sample.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Frank Gibson</obo:IAO_0000117>
<obo:IAO_0000118>DNA Chip</obo:IAO_0000118>
<obo:IAO_0000118>DNA-array</obo:IAO_0000118>
<obo:IAO_0000119>Web:<http://en.wikipedia.org/wiki/DNA_microarray>@2008/03/03</obo:IAO_0000119>
<rdfs:label>DNA microarray</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400149 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400149">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400147"/>
<obo:IAO_0000111>protein microarray</obo:IAO_0000111>
<obo:IAO_0000112>The most common protein microarray is the antibody microarray, where antibodies are spotted onto the protein chip and are used as capture molecules to detect proteins from cell lysate solutions.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A protein-microarray is a microarray, ususlly a piece of glass, on which different molecules of protein have been affixed at separate locations in an ordered manner. These are used to identify protein-protein or protein-small molecule interactions.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Daniel Schober</obo:IAO_0000119>
<rdfs:label>protein microarray</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400153 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400153">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000932"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000403"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>droplet sorter</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A droplet sorter is part_of a flow cytometer sorter that converts the carrier fluid stream into individual droplets, and these droplets are directed into separate locations for recovery (enriching the original sample for particles of interest based on qualities determined by gating) or disposal.</obo:IAO_0000115>
<obo:IAO_0000117>OBI Instrument branch</obo:IAO_0000117>
<obo:IAO_0000119>OBI Instrument branch</obo:IAO_0000119>
<rdfs:label>droplet sorter</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400155 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400155">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400120"/>
<obo:IAO_0000111>water bath</obo:IAO_0000111>
<obo:IAO_0000112>A water bath was used to allow for cell incubation at 38 degree centigrade for 8 hours.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A water bath is a temperature control bath in which a water acts as contact medium enabling temperature transfer from the heating element or cooling element to the sample. The temperature can be controlled in the 0 to 100 degree centigrade range (under normal pressure).</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Daniel Schober</obo:IAO_0000119>
<rdfs:label>water bath</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400157 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400157">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0400120"/>
<obo:IAO_0000111>oil bath</obo:IAO_0000111>
<obo:IAO_0000112>An oil bath was used to allow for fast reaction of two chemical compounds during a 2 hour period.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An oil bath is a temperature control bath in which oil acts as contact medium for the temperature transfer (from heating or cooling elements to the sample).</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Daniel Schober</obo:IAO_0000119>
<rdfs:label>oil bath</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400158 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400158">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000393"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>digital-to-analog converter</obo:IAO_0000111>
<obo:IAO_0000112>A digital-to-analog_converter is used to convert a computergenerated discrete signal into a continuous analog one, e.g. a sound.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A digital-to-analog_converter is an instrument that converts a finite resolution digital signal into an infinite resolution analog signal.</obo:IAO_0000115>
<obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Daniel Schober</obo:IAO_0000119>
<rdfs:label>digital-to-analog converter</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400168 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400168">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000932"/>
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<rdfs:subClassOf>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000379"/>
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</rdfs:subClassOf>
<obo:IAO_0000111>microtome</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 9974145.Serial sectioning of thick tissue with a novel vibrating blade microtome. Brain Res Brain Res Protoc. 1999 Jan;3(3):302-7.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A microtome is a mechanical instrument used to cut biological specimens into very thin segments for further treatment (e.g. ISH) and ultimately microscopic or histologic examination. Most microtomes provide cooling facilities (cryo-microtome) and use a steel blade to cut a slice of defined thickness. Some are automatic, and some are driven by hand.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Phillippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: Daniel Schober</obo:IAO_0000119>
<rdfs:label>microtome</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400169 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400169">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000398"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000369"/>
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<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000397"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>microscope</obo:IAO_0000111>
<obo:IAO_0000112>PMID:18466942. A light and transmission electron microscope study of hepatic portal tracts in the rhesus monkey (Macacus rhesus). Tissue Cell. 2008 May 6</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A microscope is an instrument which magnifies the view on objects (too small to be viewed by the naked eye) under increased resolution. A microscope can be an optical instrument but also and electronic instrument. There are various kind of optical microscopes, e.g confocal microscope, epifluoresence microscope)</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Phillippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>wikipedia</obo:IAO_0000119>
<rdfs:label>microscope</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400170 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400170">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000399"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>microscope slide</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 9668975.Microscope slide for enhanced analysis of DNA damage using the comet assay.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A microscope slide is a device usually made of glass which is used as a solid matrix for (biological) material deposited on its surface and which is compatible for use with a microscope instrument</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Phillippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>OBI biomaterial branch</obo:IAO_0000119>
<rdfs:label>microscope slide</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0400171 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0400171">
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000370"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>animal cage</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 18246864.Barthold SW.Effects of cage density on behavior in young adult mice.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A processed material which has the function to define a bounded habitat which is amenable to keeping animals.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Phillippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>laboratory cage</obo:IAO_0000118>
<obo:IAO_0000119>OBI biomaterial branch</obo:IAO_0000119>
<rdfs:label>animal cage</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0500000 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0500000">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000104"/>
<rdfs:subClassOf>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000272"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">study design</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">a matched pairs study design describes criteria by which subjects are identified as pairs which then undergo the same protocols, and the data generated is analyzed by comparing the differences between the paired subjects, which constitute the results of the executed study design.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A plan specification comprised of protocols (which may specify how and what kinds of data will be gathered) that are executed as part of an investigation and is realized during a study design execution.</obo:IAO_0000115>
<obo:IAO_0000116>Editor note: there is at least an implicit restriction on the kind of data transformations that can be done based on the measured data available.</obo:IAO_0000116>
<obo:IAO_0000117>PERSON: Chris Stoeckert</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">experimental design</obo:IAO_0000118>
<obo:IAO_0000232 xml:lang="en">rediscussed at length (MC/JF/BP). 12/9/08). The definition was clarified to differentiate it from protocol.</obo:IAO_0000232>
<rdfs:label xml:lang="en">study design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0500001 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0500001">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
<obo:IAO_0000111>clinical study design</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 17655677.J Cardiovasc Electrophysiol. 2007 Aug;18(9):965-71.Biventricular versus right ventricular pacing in patients with AV block (BLOCK HF): clinical study design and rationale.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">Plan for the precise procedure to be followed in a clinical trial, including planned and actual timing of events, choice of control group, method of allocating treatments, blinding methods; assigns a subject to pass through one or more epochs in the course of a trial. Specific design elements, e.g., crossover, parallel; dose-escalation [Modified from Pocock, Clinical Trials: A Practical Approach]</obo:IAO_0000115>
<obo:IAO_0000116>The definition needs to be extended to other things than simply patients</obo:IAO_0000116>
<obo:IAO_0000117>PlanAndPlannedProcess Branch</obo:IAO_0000117>
<obo:IAO_0000119>Clinical Research Glossary Version 4.0 CDICS glossary group</obo:IAO_0000119>
<rdfs:label>clinical study design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0500002 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0500002">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000115"/>
<obo:IAO_0000111>repeated measure design</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 10959922.J Biopharm Stat. 2000 Aug;10(3):433-45.Equivalence in test assay method comparisons for the repeated-measure, matched-pair design in medical device studies: statistical considerations.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a study design which use the same individuals and exposure them to a set of conditions. The effect of order and practice can be confounding factor in such designs</obo:IAO_0000115>
<obo:IAO_0000117>PlanAndPlannedProcess Branch</obo:IAO_0000117>
<obo:IAO_0000119>http://www.holah.karoo.net/experimentaldesigns.htm</obo:IAO_0000119>
<rdfs:label>repeated measure design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0500003 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0500003">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500002"/>
<obo:IAO_0000111>cross over design</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 17601993-Objective: HIV-infected patients with lipodystrophy (HIV-lipodystrophy) are insulin resistant and have elevated plasma free fatty acid (FFA) concentrations. We aimed to explore the mechanisms underlying FFA-induced insulin resistance in patients with HIV-lipodystrophy. Research Design and Methods: Using a randomized placebo-controlled cross-over design, we studied the effects of an overnight acipimox-induced suppression of FFA on glucose and FFA metabolism by using stable isotope labelled tracer techniques during basal conditions and a two-stage euglycemic, hyperinsulinemic clamp (20 mU insulin/m(2)/min; 50 mU insulin/m(2)/min) in nine patients with nondiabetic HIV-lipodystrophy. All patients received antiretroviral therapy. Biopsies from the vastus lateralis muscle were obtained during each stage of the clamp. Results: Acipimox treatment reduced basal FFA rate of appearance by 68.9% (52.6%-79.5%) and decreased plasma FFA concentration by 51.6 % (42.0%-58.9%), (both, P < 0.0001). Endogenous glucose production was not influenced by acipimox. During the clamp the increase in glucose-uptake was significantly greater after acipimox treatment compared to placebo (acipimox: 26.85 (18.09-39.86) vs placebo: 20.30 (13.67-30.13) mumol/kg/min; P < 0.01). Insulin increased phosphorylation of Akt (Thr(308)) and GSK-3beta (Ser(9)), decreased phosphorylation of glycogen synthase (GS) site 3a+b and increased GS-activity (I-form) in skeletal muscle (P < 0.01). Acipimox decreased phosphorylation of GS (site 3a+b) (P < 0.02) and increased GS-activity (P < 0.01) in muscle. Conclusion: The present study provides direct evidence that suppression of lipolysis in patients with HIV-lipodystrophy improves insulin-stimulated peripheral glucose-uptake. The increased glucose-uptake may in part be explained by increased dephosphorylation of GS (site 3a+b) resulting in increased GS activity.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a repeated measure design which ensures that experimental units receive, in sequence, the treatment (or the control), and then, after a specified time interval (aka *wash-out periods*), switch to the control (or treatment). In this design, subjects (patients in human context) serve as their own controls, and randomization may be used to determine the ordering which a subject receives the treatment and control</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>(source: http://www.sbu.se/Filer/Content0/publikationer/1/literaturesearching_1993/glossary.html)</obo:IAO_0000119>
<rdfs:label>cross over design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0500004 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0500004">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500003"/>
<obo:IAO_0000111>n-to-1 design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">N-of-1 design is a cross-over design in which the same patient is repeatedly randomised to receive either the experimental treatment or its control (Senn, 1993).</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>Adapted from http://www.childrens-mercy.org/stats/definitions/crossover.htm and source:http://symptomresearch.nih.gov/chapter_6/sec1/csss1pg1.htm)</obo:IAO_0000119>
<rdfs:label>n-to-1 design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0500005 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0500005">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
<obo:IAO_0000111>matched pairs design</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 17288613-BSTRACT: BACKGROUND: Physicians in Canadian emergency departments (EDs) annually treat 185,000 alert and stable trauma victims who are at risk for cervical spine (C-spine) injury. However, only 0.9% of these patients have suffered a cervical spine fracture. Current use of radiography is not efficient. The Canadian C-Spine Rule is designed to allow physicians to be more selective and accurate in ordering C-spine radiography, and to rapidly clear the C-spine without the need for radiography in many patients. The goal of this phase III study is to evaluate the effectiveness of an active strategy to implement the Canadian C-Spine Rule into physician practice. Specific objectives are to: 1) determine clinical impact, 2) determine sustainability, 3) evaluate performance, and 4) conduct an economic evaluation. METHODS: We propose a matched-pair cluster design study that compares outcomes during three consecutive 12-months before, after, and decay periods at six pairs of intervention and control sites. These 12 hospital ED sites will be stratified as teaching or community hospitals, matched according to baseline C-spine radiography ordering rates, and then allocated within each pair to either intervention or control groups. During the after period at the intervention sites, simple and inexpensive strategies will be employed to actively implement the Canadian C-Spine Rule. The following outcomes will be assessed: 1) measures of clinical impact, 2) performance of the Canadian C-Spine Rule, and 3) economic measures. During the 12-month decay period, implementation strategies will continue, allowing us to evaluate the sustainability of the effect. We estimate a sample size of 4,800 patients in each period in order to have adequate power to evaluate the main outcomes. DISCUSSION: Phase I successfully derived the Canadian C-Spine Rule and phase II confirmed the accuracy and safety of the rule, hence, the potential for physicians to improve care. What remains unknown is the actual change in clinical behaviors that can be affected by implementation of the Canadian C-Spine Rule, and whether implementation can be achieved with simple and inexpensive measures. We believe that the Canadian C-Spine Rule has the potential to significantly reduce health care costs and improve the efficiency of patient flow in busy Canadian EDs.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A matched pair design is a study design which use groups of individuals associated (hence matched) to each other based on a set of criteria, one member going to one treatment, the other member receiving the other treatment.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>http://www.holah.karoo.net/experimentaldesigns.htm</obo:IAO_0000119>
<rdfs:label>matched pairs design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0500006 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0500006">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
<obo:IAO_0000111>parallel group design</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 17408389-Purpose: Proliferative vitreoretinopathy (PVR) is the most important reason for blindness following retinal detachment. Presently, vitreous tamponades such as gas or silicone oil cannot contact the lower part of the retina. A heavier-than-water tamponade displaces the inflammatory and PVR-stimulating environment from the inferior area of the retina. The Heavy Silicone Oil versus Standard Silicone Oil Study (HSO Study) is designed to answer the question of whether a heavier-than-water tamponade improves the prognosis of eyes with PVR of the lower retina. Methods: The HSO Study is a multicentre, randomized, prospective controlled clinical trial comparing two endotamponades within a two-arm parallel group design. Patients with inferiorly and posteriorly located PVR are randomized to either heavy silicone oil or standard silicone oil as a tamponading agent. Three hundred and fifty consecutive patients are recruited per group. After intraoperative re-attachment, patients are randomized to either standard silicone oil (1000 cSt or 5000 cSt) or Densiron((R)) as a tamponading agent. The main endpoint criteria are complete retinal attachment at 12 months and change of visual acuity (VA) 12 months postoperatively compared with the preoperative VA. Secondary endpoints include complete retinal attachment before endotamponade removal, quality of life analysis and the number of retina affecting re-operation within 1 year of follow-up. Results: The design and early recruitment phase of the study are described. Conclusions: The results of this study will uncover whether or not heavy silicone oil improves the prognosis of eyes with PVR.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A parallel group design or independent measure design is a study design which uses unique experimental unit each experimental group, in other word no two individuals are shared between experimental groups, hence also known as parallel group design. Subjects of a treatment group receive a unique combination of independent variable values making up a treatment</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>independent measure design</obo:IAO_0000118>
<obo:IAO_0000119>http://www.holah.karoo.net/experimentaldesigns.htm</obo:IAO_0000119>
<rdfs:label>parallel group design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0500007 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0500007">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000115"/>
<obo:IAO_0000111>randomized complete block design</obo:IAO_0000111>
<obo:IAO_0000112>http://www.stats.gla.ac.uk/steps/glossary/anova.html,(A researcher is carrying out a study of the effectiveness of four different skin creams for the treatment of a certain skin disease. He has eighty subjects and plans to divide them into 4 treatment groups of twenty subjects each. Using a randomised blocks& design, the subjects are assessed and put in blocks of four according to how severe their skin condition is; the four most severe cases are the first block, the next four most severe cases are the second block, and so on to the twentieth block. The four &members of each block are then randomly assigned, one to each of the four treatment groups. http://www.stats.gla.ac.uk/steps/glossary/anova.html#rbd))</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A randomized complete block design is_a study design which assigns randomly treatments to block. The number of units per block equals the number of treatment so each block receives each treatment exactly once (hence the qualifier 'complete'). The design was originally devised from field trials used in agronomy and agriculture. The analysis assumes that there is no interaction between block and treatment. The method was then used in other settings So The randomised complete block design is a design in which the subjects are matched according to a variable which the experimenter wishes to control. The subjects are put into groups (blocks) of the same size as the number of treatments. The members of each block are then randomly assigned to different treatment groups.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>http://www.tufts.edu/~gdallal/ranblock.htm</obo:IAO_0000119>
<rdfs:label>randomized complete block design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0500008 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0500008">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500014"/>
<obo:IAO_0000111>balanced incomplete block design</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 7622388.Health Educ Q. 1995 May;22(2):201-10.Balanced incomplete block design: description, case study, and implications for practice.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">balanced incomplete block design is a kind of factorial design where all treatment pairs occur together within a block an equal number ?? times. ??ii' is the number of times treatment i occurs with i'</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Block_design and http://www.stat.psu.edu/~jglenn/stat503/05_factorial/02_factorial_IBD.html</obo:IAO_0000119>
<rdfs:label>balanced incomplete block design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0500009 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0500009">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
<obo:IAO_0000111>loop design</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 12933549</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A loop experiment design is where labeled extracts are compared in consecutive pairs. synonym: circular design</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra on behalf of MO</obo:IAO_0000117>
<obo:IAO_0000119>MO_912</obo:IAO_0000119>
<rdfs:label>loop design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0500010 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0500010">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
<obo:IAO_0000111>reference design</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 12933549</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A reference experiment design type is where all samples are compared to a common reference.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra on behalf of MO</obo:IAO_0000117>
<obo:IAO_0000119>MO_699</obo:IAO_0000119>
<rdfs:label>reference design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0500011 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0500011">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500007"/>
<obo:IAO_0000111>latin square design</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 17582121-Our objective was to examine the effects of dietary cation-anion difference (DCAD) with different concentrations of dietary crude protein (CP) on performance and acid-base status in early lactation cows. Six lactating Holstein cows averaging 44 d in milk were used in a 6 x 6 Latin square design with a 2 x 3 factorial arrangement of treatments: DCAD of -3, 22, or 47 milliequivalents (Na + K - Cl - S)/100 g of dry matter (DM), and 16 or 19% CP on a DM basis. Linear increases with DCAD occurred in DM intake, milk fat percentage, 4% fat-corrected milk production, milk true protein, milk lactose, and milk solids-not-fat. Milk production itself was unaffected by DCAD. Jugular venous blood pH, base excess and HCO3(-) concentration, and urine pH increased, but jugular venous blood Cl- concentration, urine titratable acidity, and net acid excretion decreased linearly with increasing DCAD. An elevated ratio of coccygeal venous plasma essential AA to nonessential AA with increasing DCAD indicated that N metabolism in the rumen was affected, probably resulting in more microbial protein flowing to the small intestine. Cows fed 16% CP had lower urea N in milk than cows fed 19% CP; the same was true for urea N in coccygeal venous plasma and urine. Dry matter intake, milk production, milk composition, and acid-base status did not differ between the 16 and 19% CP treatments. It was concluded that DCAD affected DM intake and performance of dairy cows in early lactation. Feeding 16% dietary CP to cows in early lactation, compared with 19% CP, maintained lactation performance while reducing urea N excretion in milk and urine.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">Latin square design is_a study design which allows in its simpler form controlling 2 levels of nuisance variables (also known as blocking variables).he 2 nuisance factors are divided into a tabular grid with the property that each row and each column receive each treatment exactly once.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>Adapted from: http://www.itl.nist.gov/div898/handbook/pri/section3/pri3321.htm and</obo:IAO_0000119>
<rdfs:label>latin square design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0500012 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0500012">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500007"/>
<obo:IAO_0000111>graeco latin square design</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 6846242-Beaton et al (Am J Clin Nutr 1979;32:2546-59) reported on the partitioning of variance in 1-day dietary data for the intake of energy, protein, total carbohydrate, total fat, classes of fatty acids, cholesterol, and alcohol. Using the same food intake data and the expanded National Heart, Lung and Blood Institute food composition data base, these analyses of sources of variance have been expanded to include classes of carbohydrate, vitamin A, vitamin C, thiamin, riboflavin, niacin, calcium, iron, total ash, caffeine, and crude fiber. The analyses relate to observed intakes (replicated six times) of 30 adult males and 30 adult females obtained under a paired Graeco-Latin square design with sequence of interview, interviewer, and day of the week as determinants. Neither sequence nor interviewer made consistent contribution to variance. In females, day of the week had a significant effect for several nutrients. The major partitioning of variance was between interindividual variation (between subjects) and intraindividual variation (within subjects) which included both true day-to-day variation in intake and methodological variation. For all except caffeine, the intraindividual variability of 1-day data was larger than the interindividual variability. For vitamin A, almost all of the variance was associated with day-to-day variability. One day data provide a very inadequate estimate of usual intake of individuals. In the design of nutrition studies it is critical that the intended use of dietary data be a major consideration in deciding on methodology. There is no ideal dietary method. There may be preferred methods for particular purposes.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">Greco-Latin square design is a study design which relates to Latin square design</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>Adapted from: http://www.itl.nist.gov/div898/handbook/pri/section3/pri3321.htm and</obo:IAO_0000119>
<obo:IAO_0000232>only 2 articles in pubmed ->probably irrelevant</obo:IAO_0000232>
<rdfs:label>graeco latin square design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0500013 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0500013">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500007"/>
<obo:IAO_0000111>hyper graeco latin square design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">PRS to do</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>Adapted from: http://www.itl.nist.gov/div898/handbook/pri/section3/pri3321.htm and</obo:IAO_0000119>
<obo:IAO_0000232>no example found in pubmed->not in use in the community</obo:IAO_0000232>
<rdfs:label>hyper graeco latin square design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0500014 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0500014">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
<obo:IAO_0000111>factorial design</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 17582121-Our objective was to examine the effects of dietary cation-anion difference (DCAD) with different concentrations of dietary crude protein (CP) on performance and acid-base status in early lactation cows. Six lactating Holstein cows averaging 44 d in milk were used in a 6 x 6 Latin square design with a 2 x 3 factorial arrangement of treatments: DCAD of -3, 22, or 47 milliequivalents (Na + K - Cl - S)/100 g of dry matter (DM), and 16 or 19% CP on a DM basis. Linear increases with DCAD occurred in DM intake, milk fat percentage, 4% fat-corrected milk production, milk true protein, milk lactose, and milk solids-not-fat. Milk production itself was unaffected by DCAD. Jugular venous blood pH, base excess and HCO3(-) concentration, and urine pH increased, but jugular venous blood Cl- concentration, urine titratable acidity, and net acid excretion decreased linearly with increasing DCAD. An elevated ratio of coccygeal venous plasma essential AA to nonessential AA with increasing DCAD indicated that N metabolism in the rumen was affected, probably resulting in more microbial protein flowing to the small intestine. Cows fed 16% CP had lower urea N in milk than cows fed 19% CP; the same was true for urea N in coccygeal venous plasma and urine. Dry matter intake, milk production, milk composition, and acid-base status did not differ between the 16 and 19% CP treatments. It was concluded that DCAD affected DM intake and performance of dairy cows in early lactation. Feeding 16% dietary CP to cows in early lactation, compared with 19% CP, maintained lactation performance while reducing urea N excretion in milk and urine.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">factorial design is_a study design which is used to evaluate two or more factors simultaneously. The treatments are combinations of levels of the factors. The advantages of factorial designs over one-factor-at-a-time experiments is that they are more efficient and they allow interactions to be detected. In statistics, a factorial design experiment is an experiment whose design consists of two or more factors, each with discrete possible values or levels, and whose experimental units take on all possible combinations of these levels across all such factors. Such an experiment allows studying the effect of each factor on the response variable, as well as the effects of interactions between factors on the response variable.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>http://www.stats.gla.ac.uk/steps/glossary/anova.html#facdes And from wikipedia (01/03/2007): http://en.wikipedia.org/wiki/Factorial_experiment)</obo:IAO_0000119>
<rdfs:label>factorial design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0500015 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0500015">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500014"/>
<obo:IAO_0000111>2x2 factorial design</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 17561240-The present experiment evaluates the effects of intermittent exposure to a social stimulus on ethanol and water drinking in rats. Four groups of rats were arranged in a 2x2 factorial design with 2 levels of Social procedure (Intermittent Social vs Continuous Social) and 2 levels of sipper Liquid (Ethanol vs Water). Intermittent Social groups received 35 trials per session. Each trial consisted of the insertion of the sipper tube for 10 s followed by lifting of the guillotine door for 15 s. The guillotine door separated the experimental rat from the conspecific rat in the wire mesh cage during the 60 s inter-trial interval. The Continuous Social groups received similar procedures except that the guillotine door was raised during the entire duration of the session. For the Ethanol groups, the concentrations of ethanol in the sipper [3, 4, 6, 8, 10, 12, 14, and 16% (vol/vol)] increased across sessions, while the Water groups received 0% ethanol (water) in the sipper throughout the experiment. Both Social procedures induced more intake of ethanol than water. The Intermittent Social procedure induced more ethanol intake at the two highest ethanol concentration blocks (10-12% and 14-16%) than the Continuous Social procedure, but this effect was not observed with water. Effects of social stimulation on ethanol drinking are discussed.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a factorial design which has 2 experimental factors (aka independent variables) and 2 factor levels per experimental factors</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>PMID: 17561240</obo:IAO_0000119>
<rdfs:label>2x2 factorial design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0500016 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0500016">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500014"/>
<obo:IAO_0000111>fractional factorial design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A fractional factorial design is_a study design in which only an adequately chosen fraction of the treatment combinations required for the complete factorial experiment is selected to be run</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119>http://www.itl.nist.gov/div898/handbook/pri/section3/pri334.htm From ASQC (1983) Glossary & Tables for Statistical Quality Control</obo:IAO_0000119>
<rdfs:label>fractional factorial design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0500017 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0500017">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
<obo:IAO_0000111>dye swap design</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 17411393-Dye-specific bias effects, commonly observed in the two-color microarray platform, are normally corrected using the dye swap design. This design, however, is relatively expensive and labor-intensive. We propose a self-self hybridization design as an alternative to the dye swap design. In this design, the treated and control samples are labeled with Cy5 and Cy3 (or Cy3 and Cy5), respectively, without dye swap, along with a set of self-self hybridizations on the control sample. We compare this design with the dye swap design through investigation of mouse primary hepatocytes treated with three peroxisome proliferator-activated receptor-alpha (PPARalpha) agonists at three dose levels. Using Agilent's Whole Mouse Genome microarray, differentially expressed genes (DEG) were determined for both the self-self hybridization and dye swap designs. The DEG concordance between the two designs was over 80% across each dose treatment and chemical. Furthermore, 90% of DEG-associated biological pathways were in common between the designs, indicating that biological interpretations would be consistent. The reduced labor and expense for the self-self hybridization design make it an efficient substitute for the dye swap design. For example, in larger toxicogenomic studies, only about half the chips are required for the self-self hybridization design compared to that needed in the dye swap design.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">An experiment design type where the label orientations are reversed. exact synonym: flip dye, dye flip</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra on behalf of MO</obo:IAO_0000117>
<obo:IAO_0000119>MO_858</obo:IAO_0000119>
<rdfs:label>dye swap design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0500018 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0500018">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
<obo:IAO_0000111>replicate design</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A replicate experimental design type is where a series of replicates are performed to evaluate reproducibility or as a pilot study to determine the appropriate number of replicates for a subsequent experiments.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra on behalf of MO</obo:IAO_0000117>
<obo:IAO_0000119>MO_885</obo:IAO_0000119>
<rdfs:label>replicate design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0500019 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0500019">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
<obo:IAO_0000111>self vs self design</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 17411393-Dye-specific bias effects, commonly observed in the two-color microarray platform, are normally corrected using the dye swap design. This design, however, is relatively expensive and labor-intensive. We propose a self-self hybridization design as an alternative to the dye swap design. In this design, the treated and control samples are labeled with Cy5 and Cy3 (or Cy3 and Cy5), respectively, without dye swap, along with a set of self-self hybridizations on the control sample. We compare this design with the dye swap design through investigation of mouse primary hepatocytes treated with three peroxisome proliferator-activated receptor-alpha (PPARalpha) agonists at three dose levels. Using Agilent's Whole Mouse Genome microarray, differentially expressed genes (DEG) were determined for both the self-self hybridization and dye swap designs. The DEG concordance between the two designs was over 80% across each dose treatment and chemical. Furthermore, 90% of DEG-associated biological pathways were in common between the designs, indicating that biological interpretations would be consistent. The reduced labor and expense for the self-self hybridization design make it an efficient substitute for the dye swap design. For example, in larger toxicogenomic studies, only about half the chips are required for the self-self hybridization design compared to that needed in the dye swap design.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A study design that investigates variance and error estimates in the experimental system, and is where the same extract is compared.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra on behalf of MO</obo:IAO_0000117>
<obo:IAO_0000119>MO_490</obo:IAO_0000119>
<rdfs:label>self vs self design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0500020 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0500020">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
<obo:IAO_0000111>time series design</obo:IAO_0000111>
<obo:IAO_0000112>PMID: 14744830-Microarrays are powerful tools for surveying the expression levels of many thousands of genes simultaneously. They belong to the new genomics technologies which have important applications in the biological, agricultural and pharmaceutical sciences. There are myriad sources of uncertainty in microarray experiments, and rigorous experimental design is essential for fully realizing the potential of these valuable resources. Two questions frequently asked by biologists on the brink of conducting cDNA or two-colour, spotted microarray experiments are 'Which mRNA samples should be competitively hybridized together on the same slide?' and 'How many times should each slide be replicated?' Early experience has shown that whilst the field of classical experimental design has much to offer this emerging multi-disciplinary area, new approaches which accommodate features specific to the microarray context are needed. In this paper, we propose optimal designs for factorial and time course experiments, which are special designs arising quite frequently in microarray experimentation. Our criterion for optimality is statistical efficiency based on a new notion of admissible designs; our approach enables efficient designs to be selected subject to the information available on the effects of most interest to biologists, the number of arrays available for the experiment, and other resource or practical constraints, including limitations on the amount of mRNA probe. We show that our designs are superior to both the popular reference designs, which are highly inefficient, and to designs incorporating all possible direct pairwise comparisons. Moreover, our proposed designs represent a substantial practical improvement over classical experimental designs which work in terms of standard interactions and main effects. The latter do not provide a basis for meaningful inference on the effects of most interest to biologists, nor make the most efficient use of valuable and limited resources.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">Groups of assays that are related as part of a time series.</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra on behalf of MO</obo:IAO_0000117>
<obo:IAO_0000119>MO_887</obo:IAO_0000119>
<rdfs:label>time series design</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0500022 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0500022">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000055"/>
<obo:IAO_0000111 xml:lang="en">stopping rule</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PMID: 17591081-BACKGROUND/AIMS: To investigate the viral kinetics of Chinese CHC patients received pegylated interferon plus ribavirin and examine the impact of HCV genotypes and severity of liver disease. METHODOLOGY: 65 treatment-naove CHC patients who finished a 24-week therapy with peginterferon (alpha-2b (1.5 mcg/kg/week) plus ribavirin (1000-1200 mg /day) and 24 weeks of follow-up were enrolled. Hepatic fibrosis was graded by the METAVIR scoring system. Serum quantitative HCV RNA was determined by Versant HCV RNA 3.0 assay (Bayer Inc.). RESULTS: Genotype non-1 patients responded quickly and a higher percentage of them achieved undetectable HCV RNA (< 615 IU/mL) at week 4 compared with genotype 1 patients (93% vs. 69%, p = 0.018). Degree of hepatic fibrosis significantly affected end-of-treatment and sustained response (SVR). For patients who did not achieve early virological response (EVR), the negative predictive value for SVR was 100%. In genotype 1 patients, undetectable HCV RNA by week 4 was a good marker to predict treatment response, with a positive predictive value of 84% and a negative predictive value of 82%. CONCLUSIONS: EVR can be applied to Chinese patients as an early stopping rule. A 24-week duration of pegylated IFN/ribavirin might be adequate for genotype 1 patients who rapidly responded to therapy.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">a stopping rule (criterion) is_a *rule* which causes a *stopping process* to happen</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PRS</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PRS</obo:IAO_0000119>
<rdfs:label xml:lang="en">stopping rule</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0500023 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0500023">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000055"/>
<obo:IAO_0000111 xml:lang="en">compliance rule</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">a compliance rule is a rule which ensures a compliance process occurs</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PRS</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PRS</obo:IAO_0000119>
<rdfs:label xml:lang="en">compliance rule</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0500024 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0500024">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500023"/>
<obo:IAO_0000111 xml:lang="en">standard compliance rule</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">a standard compliance rule is a compliance rule which defines conformity to a representation standard</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PRS</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PRS</obo:IAO_0000119>
<rdfs:label xml:lang="en">standard compliance rule</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0500025 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0500025">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500024"/>
<obo:IAO_0000111 xml:lang="en">ethical standard compliance rule</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">an ethical standard compliance rule is_a *compliance rule* which enable a *ethical compliance process* to occur</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PRS</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PRS</obo:IAO_0000119>
<rdfs:label xml:lang="en">ethical standard compliance rule</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0500026 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0500026">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001755"/>
<obo:IAO_0000111 xml:lang="en">eligibility criterion</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PMID: 17579629 -Eligibility criteria included: untreated ED-SCLC; age >/=70 and performance status 0-2, or age <70 and PS 3.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">an eligibility criterion (rule) is_a selection criterion which
defines and states the requirements (positive or negative) for an entity to be considered as suitable for a given task or participation in a process.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">eligibility rule</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">Adapted from Clinical Research Glossary Version 4.0 CDICS glossary group</obo:IAO_0000119>
<rdfs:label xml:lang="en">eligibility criterion</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0500027 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0500027">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500026"/>
<obo:IAO_0000111 xml:lang="en">inclusion criterion</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PMID: 23979341-The major inclusion criterion was patients in whom severe cerebral embolism was diagnosed at age 75 or younger (more than 9 in the NIHSS score on day 7 after the onset of stroke) .</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">an inclusion criterion (rule) is_a *eligibility criterion* which defines and states a condition which, if met, makes an entity suitable for a given task or participation in a given process. For instance, in a study protocol, inclusion criteria indicate the conditions that prospective subjects MUST meet to be eligible for participation in a study.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">inclusion condition</obo:IAO_0000118>
<obo:IAO_0000118 xml:lang="en">inclusion rule</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">Adapted from Clinical Research Glossary Version 4.0 CDICS glossary group</obo:IAO_0000119>
<rdfs:label xml:lang="en">inclusion criterion</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0500028 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0500028">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500026"/>
<obo:IAO_0000111 xml:lang="en">exclusion rule</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PMID: 17600285-Exclusion criteria included the use of any topical ophthalmic or topical oral medication and/or history of ocular or oral surgery within the past six months.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">an exclusion criterion (rule) is_a *eligibility criterion* which defines and states a condition which, if met, makes an entity unsuitable for a given task or participation in a given process. For instance, in a study protocol, exclusion criteria indicate the conditions that prospective subjects SHOULD NOT meet to be eligible for participation in a study</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person: Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">Adapted from Clinical Research Glossary Version 4.0 CDICS glossary group</obo:IAO_0000119>
<rdfs:label xml:lang="en">exclusion criterion</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600000 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600000">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000319"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000444"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100060"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000274"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100060"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100060"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000434"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">adding substance to cell culture</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">adding fetal calf serum to a 96 well plate containing a cell culture derived from a blood sample of a patient</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">is process in which a material substance is added to a cell culture</obo:IAO_0000115>
<obo:IAO_0000116>renamed from 'administering substance to cell culture', to reflect that administration is commonly used only for organisms</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">adding substance to cell culture</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600002 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600002">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100051"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000063"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>tumor grading</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">An assay that determines the grade (severity/stage) of a tumor sample, used in cancer biology to describe abnormalities/qualities of tumor cells or tissues. Values can be described by terms from NCI Thesaurus.</obo:IAO_0000115>
<obo:IAO_0000117>Compiled by Helen Parkinson for Transcriptomics thanks to Adam Witney</obo:IAO_0000117>
<obo:IAO_0000118>grading of tumor</obo:IAO_0000118>
<obo:IAO_0000119>OBI branch derived; submitted by MO</obo:IAO_0000119>
<rdfs:label>tumor grading</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600003 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600003">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete performing a clinical assessment</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A protocol application during which a series of tests are made of a patient leading to determination of disease state, or condition.</obo:IAO_0000115>
<obo:IAO_0000117>PlanAndPlannedProcess Branch</obo:IAO_0000117>
<obo:IAO_0000118>clinical diagnosis</obo:IAO_0000118>
<obo:IAO_0000119>OBI branch derived</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/623</obo:IAO_0000233>
<rdfs:label>obsolete performing a clinical assessment</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600004 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600004">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001928"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000810"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000059"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0500026"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000181"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000181"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000097"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">human subject enrollment</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">enlisting familiy members of HIV patients into a study</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A planned process with the objective to obtain a population of human subjects to participate in an investigation by determining eligibility of subjects and obtaining informed consent.</obo:IAO_0000115>
<obo:IAO_0000116>As with group assignment, should the specified output here be an organism which bears a role</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">criteria come from plan / clinical trial branch</obo:IAO_0000232>
<rdfs:label xml:lang="en">human subject enrollment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600005 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600005">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100051"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000684"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">collecting specimen from organism</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">taking a sputum sample from a cancer patient, taking the spleen from a killed mouse, collecting a urine sample from a patient</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">a process with the objective to obtain a material entity that was part of an organism for potential future use in an investigation</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON:Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">collecting specimen from organism</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600006 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600006">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100026"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000086"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0001421"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100026"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000086"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0001422"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">killing</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Terminal sacrifice of animals by cervical dislocation at the end of an investigation.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A protocol application in which an organism is intentionally put to death</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">difficult to place this properly - JG. Death process (e.g. unscheduled death) is out of scope but should be added somewhere. All killings have death process as a part, but not all death processes are part of a killing.</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">death status type</obo:IAO_0000118>
<obo:IAO_0000118 xml:lang="en">euthanisia</obo:IAO_0000118>
<obo:IAO_0000118 xml:lang="en">life termination</obo:IAO_0000118>
<obo:IAO_0000118 xml:lang="en">sacrifice</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">CEBS, Biomaterial_branch</obo:IAO_0000119>
<rdfs:label xml:lang="en">killing</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600007 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600007">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000319"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000444"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100026"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000465"/>
</owl:unionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000274"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000434"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:maxCardinality rdf:datatype="http://www.w3.org/2001/XMLSchema#nonNegativeInteger">1</owl:maxCardinality>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">administering substance in vivo</obo:IAO_0000111>
<obo:IAO_0000112>Balb/c mice received an intracameral or subconjunctival injection of trinitrophenylated spleen cells</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">injecting mice with 10 ug morphine intranasally, a patient taking two pills of 1 mg aspirin orally</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A process by which a substance is intentionally given to an organism resulting in exposure of the organism to that substance.</obo:IAO_0000115>
<obo:IAO_0000116>2009-11-10. Tracker: https://sourceforge.net/tracker/?func=detail&aid=2893050&group_id=177891&atid=886178</obo:IAO_0000116>
<obo:IAO_0000116 xml:lang="en">Different routes and means of administration should go as children underneath this</obo:IAO_0000116>
<obo:IAO_0000116>Update the definition based on the discussion. Details see the tracker:
https://sourceforge.net/p/obi/obi-terms/738/</obo:IAO_0000116>
<obo:IAO_0000116 xml:lang="en">needs roles such as perturber and perturbee (children of input role). Perturb is too strong. Host might be the name for one role. Others considered: Doner, Donated, Acceptor.</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Person:Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">administering substance in vivo</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600008 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600008">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001928"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000059"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001755"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000030"/>
</owl:unionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">acquisition</obo:IAO_0000111>
<obo:IAO_0000112>Downloading a 3D structure from the PDB. Purchasing antibodies from sigma.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A planned process with the objective of gaining possession of an entity.</obo:IAO_0000115>
<obo:IAO_0000116>5/31/2012 - OBI workshop: This process is not implying ownership of the material / information.</obo:IAO_0000116>
<obo:IAO_0000116 xml:lang="en">Following OBI call November 2012,5th:
addition of a restriction to acquisition class to capture the need of having selection criteria
Relates to the creation of a class 'selection rule'</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">This needs to be fleshed out and logical definitions added that will allow to place the children terms automatically under acquisition</obo:IAO_0000232>
<rdfs:label xml:lang="en">acquisition</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600009 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600009">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<obo:IAO_0000111 xml:lang="en">exposure of material to environment</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Putting cells in a freezer at -80C. Cy5-labeled DNA is irradiated with a laser to excite the fluorophore. Inducing a phase transition in a material by putting it in an environment with a specific temperature. Oxygen deprivation in a chamber.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a planned process in which an input material is exposed to a defined set of conditions in a controlled environment. The environment is a specified input.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">Alan says there will be problmes, e.g. with selection by survival</obo:IAO_0000232>
<rdfs:label xml:lang="en">exposure of material to environment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600010 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600010">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600008"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">material acquisition</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Acquiring 50 C57BL/6 mice bred in the animal facility of the institute as a service to investigators. Purchasing 1 mg of peptides synthesized by Mimotopes at 80% purity. Getting a gift of purified CD4+ specific antibodies presented by Stephen Schoenberger at LIAI.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An acquisition in which possession of a material entity is gained.</obo:IAO_0000115>
<obo:IAO_0000116>The assumption is that the object already exists in its current state, e.g, an available mouse strain purchased from the Jackson Lab, this is the differentia from specimen creation</obo:IAO_0000116>
<obo:IAO_0000116>This excludes processes that create or change materials, such as material transformations.</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Bjoern Peters, Alan Ruttenberg, Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000118>material procurement</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">material acquisition</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600011 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600011">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600009"/>
<obo:IAO_0000111 xml:lang="en">acclimatization</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">placing mice in animal facility for 2 weeks prior to an experiment to accustom them to their environment, reducing stress</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A protocol application in which an object is left in an environment for some period of time, until some qualities of interest are in equilibrium with that environment.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">CEBS, Biomaterial_branch</obo:IAO_0000119>
<rdfs:label xml:lang="en">acclimatization</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600012 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600012">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/ENVO_00010483"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100051"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000684"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">environmental material collection</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Taking 1 liter of surface ocean water from the San Diego Mission Bay Jetty. Capturing mice living in rural Arkansas</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">environmental_material_collection is an acquisition where an object is taken from an environment and put into a storage container. Roles include, environment, thing collected, container, acquirer.</obo:IAO_0000115>
<obo:IAO_0000116>relabel the term and add axiom connecting to EnVO:'environmental material'
discussed on obi-dev call 9/28/2015, details see: https://sourceforge.net/p/obi/obi-terms/779/</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Bjoern Peters, Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">the researcher is very interested in the location</obo:IAO_0000232>
<rdfs:label xml:lang="en">environmental material collection process</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600013 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600013">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600008"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">information acquisition</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Gathering all influenza HA sequences from GenBank, Retrieveing HLA allele frequencies in the North American populations from dbMHC</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An acquisition in which possession of information is gained.</obo:IAO_0000115>
<obo:IAO_0000116>This excludes processes that create or change information, such as assays and data transformations.</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000118>data collection</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">information acquisition</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600014 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600014">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000639"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">material component separation</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Using a cell sorter to separate a mixture of T cells into two fractions; one with surface receptor CD8 and the other lacking the receptor, or purification</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">a material processing in which components of an input material become segregated in space</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">material component separation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600015 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600015">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000023"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">group assignment</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Assigning' to be treated with active ingredient role' to an organism during group assignment. The group is those organisms that have the same role in the context of an investigation</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">group assignment is a process which has an organism as specified input and during which a role is assigned</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>cohort assignment</obo:IAO_0000118>
<obo:IAO_0000118>study assignment</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">OBI Plan</obo:IAO_0000119>
<rdfs:label xml:lang="en">group assignment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600016 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600016">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000652"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100051"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0302716"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000686"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:minCardinality rdf:datatype="http://www.w3.org/2001/XMLSchema#nonNegativeInteger">2</owl:minCardinality>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>pooling specimens</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=104564; Combining spleens of 20 mice, Combining supernatant from a cell culture obtained at different time points</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">physical combination of several instances of like material</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PlanAndPlannedProcess Branch</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">sample pooling</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">like' is one of the things that you should be controling for in a well-designed experiment. The instances of material need to have the same class.</obo:IAO_0000232>
<rdfs:label xml:lang="en">pooling specimens</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600017 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600017">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001936"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001936"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>assay detecting a molecular label</obo:IAO_0000111>
<obo:IAO_0000112>Determination of the amount of phycoerytherin label present in a cell population stained with anti-CD8-PE in order to determine the percentage of CD8+ T cells present</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">An assay that detects the presence or a quality of a molecular label which is a proxy for the detection of the molecular target to which the label is attached</obo:IAO_0000115>
<obo:IAO_0000117>Matthew Brush</obo:IAO_0000117>
<obo:IAO_0000119>OBI developer call, 3-12-12</obo:IAO_0000119>
<rdfs:label>assay detecting a molecular label</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600018 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600018">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600014"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000678"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">material portioning</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">pouring 50 mL aliquots of fetal calf serum into conical tubes from a 500 mL stock</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a material processing in which the input substance is partitioned into a number of portions that are similar in composition.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON:Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">aliquoting</obo:IAO_0000118>
<obo:IAO_0000118 xml:lang="en">apportioning</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">material portioning</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600019 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600019">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600038"/>
<obo:IAO_0000111 xml:lang="en">non-specific labeling</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">The addition of phycoerytherin label to an anti-CD8 antibody, to label all antibodies.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">The addition of a reagent labeling the entire input biomaterial enabling future detection of the output biomaterial</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PlanAndPlannedProcess Branch</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">definition blessed by Allyson, Bjoern, Jay & Randi</obo:IAO_0000232>
<rdfs:label xml:lang="en">non-specific labeling</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600020 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600020">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000341"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000185"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003368"/>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000000"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100066"/>
</owl:unionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>histological assay</obo:IAO_0000111>
<obo:IAO_0000112>the counting of the number of cells with fluorescent label at their surface to determine the percentage of the population which was activated</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">An assay that uses visual examination of cells or tissue (or images of them) to make an assessment regarding a quality of the cells or tissue. This assay can include steps of staining, imaging, and judgement.</obo:IAO_0000115>
<obo:IAO_0000117>Adam Witney</obo:IAO_0000117>
<obo:IAO_0000117>Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000118>histology</obo:IAO_0000118>
<obo:IAO_0000118>histopathology</obo:IAO_0000118>
<obo:IAO_0000119>OBI branch derived</obo:IAO_0000119>
<rdfs:label>histological assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600021 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600021">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000000"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100051"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_23367"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0302729"/>
</owl:unionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">cell fixation</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">http://www.tissuearray.org/CellLinesProtocolforTMA112.pdf; the treatment of CD8+ cells with methanol at -20oC; http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&amp;list_uids=16080188&dopt=AbstractPlus</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">a protocol application to preserve defined qualities of cells or tissues (sample) which may otherwise change over time</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">should include capturing what qualities are being preserved</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">PERSON:Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">we could generalize this for other input materials</obo:IAO_0000232>
<rdfs:label xml:lang="en">cell fixation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600022 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600022">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600014"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000681"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">excision</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Cutting out the portion of a gel which contains a DNA fragment</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">the use physical means to remove a portion of a substance from the rest</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Alan Ruttenberg, Kevin Clancy</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">www.crohnsresource.com/glossary.jsp (via google define:resection)</obo:IAO_0000119>
<rdfs:label xml:lang="en">excision</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600023 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600023">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000231"/>
<owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/OBI_0600050"/>
<obo:IAO_0000111 xml:lang="en">non specific enzymatic cleavage</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">The use of agarase to digest an agar gel</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">an enzymatic cleavage that uses an enzyme without a strong affinity for specific cleavage sites in the input material</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON:Kevin Clancy</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">non specific enzymatic cleavage</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600024 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600024">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000838"/>
<rdfs:subClassOf>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100060"/>
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</rdfs:subClassOf>
<rdfs:subClassOf>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000079"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001912"/>
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</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
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</rdfs:subClassOf>
<rdfs:subClassOf>
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</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">maintaining cell culture</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">When harvesting blood from a human, isolating T cells, and then limited dilution cloning of the cells, the maintaining_cell_culture step comprises all steps after the initial dilution and plating of the cells into culture, e.g. placing the culture into an incubator, changing or adding media, and splitting a cell culture</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A planned process with the objective to keep cells alive in a defined environment outside of an organism.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PlanAndPlannedProcess Branch</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">maintaining cell culture</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600025 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600025">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
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</owl:Class>
</owl:someValuesFrom>
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</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>substance detection assay</obo:IAO_0000111>
<obo:IAO_0000112>the detection of phycoerytherin by means of flow cytometry</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">An assay that detects a specified substance</obo:IAO_0000115>
<obo:IAO_0000117>Kevin Clancy</obo:IAO_0000117>
<obo:IAO_0000119>OBI branch derived</obo:IAO_0000119>
<rdfs:label>substance detection assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600026 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600026">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000414"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>longitudinal mass measurement assay</obo:IAO_0000111>
<obo:IAO_0000112>The comparison of the weight of vaccinated and non-vaccinated mice after infection with influenza A over 6 weeks post-infection</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures the mass of a material at two or more time points</obo:IAO_0000115>
<obo:IAO_0000117>Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000119>OBI branch derived</obo:IAO_0000119>
<rdfs:label>longitudinal mass measurement assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600027 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600027">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">artificially induced cell membrane lysis</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&amp;list_uids=16080188&dopt=AbstractPlus; The destruction of cell membranes with detergent.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">a material transformation to break the membranes of cells, releasing the cells contents; input=>cells; output=>cell_lysate</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">---\nThere is a more general 'membrane lysis', which could apply to artificial membranes etc. For this general membrane encapsulated objects would need to be defined.</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">PlanAndPlannedProcess Branch</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">artificially induced cell membrane lysis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600028 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600028">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33697"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000419"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16991"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">artificially induced reverse transcription</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">The use of M-MLV reverse transcriptase from the Moloney murine leukemia virus to transcribe an RNA sample into cDNA</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">a protocol with the objective to transcribe single-stranded RNA into complementary DNA (cDNA)</obo:IAO_0000115>
<obo:IAO_0000116>It could also be added that the reverse transcriptase is bearer of a GO:0003964 RNA-directed DNA polymerase activity, which is realized in this process.</obo:IAO_0000116>
<obo:IAO_0000116 xml:lang="en">We need to indicate the relationship between the cDNA generated and the RNA that was used as a template. This may be outside of the OBI scope</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">PERSON:Kevin Clancy</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">artificially induced reverse transcription</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600029 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600029">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600014"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000681"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">isolation of cell culture supernatant</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Pouring out a portion of the fluid part of an adherant cell culture growing in a flask.; The centrifugation of a T cell culture followed by aspiration of the supernatant while the cellular pellet remains in the centrifuge tube.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">a protocol which results in the separation of supernatant material from a cell culture</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">This does not apply to the case where the cells are lysed</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">PlanAndPlannedProcess Branch</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">isolation of cell culture supernatant</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600030 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600030">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">experimental disease induction</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">the injection of mice with LCM virus iv to establish an LCMV infection. Witholding food from animals to induce starvation syndrome.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">a protocol application to induce a specific disease in an organism</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PlanAndPlannedProcess Branch</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">could be defined class</obo:IAO_0000232>
<rdfs:label xml:lang="en">experimental disease induction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600031 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600031">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001977"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003587"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100060"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100060"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000086"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0042571"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0042571"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>enzyme-linked immunospot assay</obo:IAO_0000111>
<obo:IAO_0000112>Determination of the frequency of cells producing IFN-gamma in response to viral peptides by placing effector cells on a anti IFN-gamma coated plate, and adding antigen presenting cells pulsed with a peptide. After washing, the bound IFN-gamma is detected with a secondary antibody linked to a dye that visualizes as one spot per cell.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay in which cells are cultured on a surface coated with a capture antibody binding a secretory material of interest which subsequently gets stained resulting in a spot for each cell producing the secretory material of interest.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000118>ELISPOT assay</obo:IAO_0000118>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>enzyme-linked immunospot assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600032 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600032">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">artificially induced DNA repair</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">the use of DNA repair enzymes uracil DNA glycosylase and 3-methyladenine DNA glycosylase to repair DNA strands</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">a protocol application to repair damaged DNA molecules</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PlanAndPlannedProcess Branch</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">---\nis this really a protocol?\n--> This as several other protocol applications is also a natural process. The fact that it is induced experimetnally by following a protocol makes it a protocol application. Need to make sure that labels don't conflict wi</obo:IAO_0000232>
<rdfs:label xml:lang="en">artificially induced DNA repair</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600033 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600033">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">cell permeabilization</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Electroporation of HeLa cells to allow transfection with pUC19.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A protocol application to permeabilize cell membranes, allowing molecules to more easily pass through the membrane than was possible prior to the protocol application</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">need to add output cell has_quality permeable</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">PERSON:Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">definition blessed by Jay, Alan, Randi</obo:IAO_0000232>
<rdfs:label xml:lang="en">cell permeabilization</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600034 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600034">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600014"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000681"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">precipitation</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">The use of ethanol to precipitate DNA molecules from a solution containing DNA</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">a protocol application to cause a material to precipitate (becoming a solid) out of solution. Input is a solution, output is a solution plus a solid component (the precipitate)</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON:Kevin Clancy</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">precipitation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600036 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600036">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000079"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100060"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>'establishing cell culture'</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a process through which a new type of cell culture or cell line is created, either through the isolation and culture of one or more cells from a fresh source, or the deliberate experimental modification of an existing cell culture (e.g passaging a primary culture to become a secondary culture or line, or the immortalization or stable genetic modification of an existing culture or line).</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Matthew Brush</obo:IAO_0000117>
<obo:IAO_0000119>PERSON:Matthew Brush</obo:IAO_0000119>
<rdfs:comment>A 'cell culture' as used here referes to a new lineage of cells in culture deriving from a single biological source.. New cultures are established through the initial isolation and culturing of cells from an organismal source, or through changes in an existing cell culture or line that result in a new culture with unique characteristics. This can occur through the passaging/selection of a primary culture into a secondary culture or line, or experimental modifications of an existing cell culture or line such as an immortalization process or other stable genetic modification. This class covers establishment of cultures of either multicellular organism cells or unicellular organisms.</rdfs:comment>
<rdfs:label>establishing cell culture</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600037 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600037">
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<rdfs:subClassOf>
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</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100060"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000678"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">cell culture splitting</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">The act of taking a cell culture of high density, counting the cells, removing part of the cells, and re-seeding a select number of the cells into new flasks with fresh tissue culture media.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">The act of taking part of a homogeneous cell culture and creating one or more additional separate cultures of similar qualities. input: cell_culture, output cell_culture min cardinality 2. part of cell culturing</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PlanAndPlannedProcess Branch</obo:IAO_0000117>
<obo:IAO_0000118>cell culture passaging</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:comment>An active cell culture is typically split when it has grown to confluence in its culture dish. Cell culture splitting of a cell culture sample results in an increase in its passage number, which measures how long a sample has been propagated in vitro, and therefore how many selective or genetic changes it is likely to have undergone.</rdfs:comment>
<rdfs:label xml:lang="en">cell culture splitting</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600038 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600038">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002744"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110109"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001936"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">addition of molecular label</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">The addition of phycoerytherin label to an anti-CD8 antibody, to label all antibodies. The addition of anti-CD8-PE to a population of cells, to label the subpopulation cells that are CD8+.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">a material processing technique intended to add a molecular label to some input material entity, to allow detection of the molecular target of this label in a detection of molecular label assay</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON:Matthew Brush</obo:IAO_0000117>
<obo:IAO_0000118>labeling</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">OBI developer call, 3-12-12</obo:IAO_0000119>
<rdfs:label xml:lang="en">addition of molecular label</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600039 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600039">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">artificially induced methylation</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">the use of enzymes to add methyl groups to DNA molecules</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A planned process of adding methyl groups to polymers</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON:Kevin Clancy</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">artificially induced methylation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600040 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600040">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>synthesis</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">making cDNA from nucleotides using RNA as a template</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">the construction of a biomaterial from simpler biomaterials</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">This probably needs breaking down into more specific applications. The example given is already covered in reverse_transcription</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">PERSON:Kevin Clancy</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">synthesize</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">synthesis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600041 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600041">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600014"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000681"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">concentrate</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Evaporation of the solution containing DNA to increase the concentration of the DNA molecules</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">a protocol application to create an output material with an increased density of a material of interest that is part of the input material by separating other parts of the input material</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON:Kevin Clancy</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">concentrate</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600042 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600042">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0600064"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000430"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000411"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000410"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600064"/>
<obo:IAO_0000111 xml:lang="en">recombinant plasmid cloning</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">The DNA fragment encoding the p35 gene from Mycobacterium avium complex was inserted into pcDNAII and expressed in E coli in order to study p35.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">the insertion of a particular DNA fragment into a plasmid in order to make copies of a biomaterial</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON:Kevin Clancy</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">recombinant plasmid cloning</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600043 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600043">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001151"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001153"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">genetic transformation</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">The transduction of E. coli through the introduction of a plasmid encoding for M. avium p35</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">the introduction. alteration or integration of genetic material into a cell or organism</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON:Kevin Clancy</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">genetic modification</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">genetic transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600044 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600044">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600014"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000639"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">lavage</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">the collection of bronchoalveolar lavage fluid (BAL) from the lungs of mice in order to study the cytokines present</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A protocol application to separate cells and/or cellular secretions from an anatomical space by the introduction and removal of fluid</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">This is not washing, in which case the material of interest is not the resulting fluid</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">PlanAndPlannedProcess Branch</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">lavage</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600045 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600045">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001155"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>3D structure determination assay</obo:IAO_0000111>
<obo:IAO_0000112>The use of X-ray crystallography to determine the 3D coordinates of atoms in a protein.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that determines the 3-dimensional configuration of an input material.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>3D structure determination assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600046 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600046">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600014"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000318"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000681"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000038"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000048"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">preparative chromatography</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">The use of gas chromatography in order separate out from an input sample of eggs a fraction that would be enriched for pesticides.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">the use of a biomaterial's preferential affinity for either the mobile phase or the stationary phase to separate it from other materials of differing affinity</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON:Kevin Clancy; Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">preparative chromatography</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600047 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600047">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001108"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001137"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0400103"/>
</owl:unionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001108"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001137"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0400103"/>
</owl:unionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001010"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
</owl:Restriction>
</owl:unionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001010"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
</owl:Restriction>
</owl:unionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000973"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/SO_0000001"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>sequencing assay</obo:IAO_0000111>
<obo:IAO_0000112>The use of the Sanger method of DNA sequencing to determine the order of the nucleotides in a DNA template</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">An assay the uses chemical or biochemical means to infer the sequence of a biomaterial</obo:IAO_0000115>
<obo:IAO_0000117>PlanAndPlannedProcess Branch</obo:IAO_0000117>
<obo:IAO_0000119>OBI branch derived</obo:IAO_0000119>
<rdfs:label>sequencing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600048 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600048">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600064"/>
<obo:IAO_0000111>vector mediated amplification</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">E coli expressing the gene for M avium p35 were cultured in order to produce p35.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">The process of creating a copy of some biological entity in cell culture</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON:Kevin Clancy</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">vector mediated amplification</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600049 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600049">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600058"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0042575"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_33697"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">DNA polymerase amplification</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">The use of taq polymerase to amplify a DNA fragment during a PCR.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">DNA polymerase amplification is an enzymatic amplification which uses DNA polymerase enzyme to make copies of a DNA contained in biomaterial used as input</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON:Kevin Clancy</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">DNA polymerase amplification</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600050 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600050">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000231"/>
<obo:IAO_0000111 xml:lang="en">specific enzymatic cleavage</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">The use of a protease to digest a protein into peptides</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">an enzymatic cleavage that uses an enzyme with a strong affinity for specific cleavage sites in the input material</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON:Kevin Clancy</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">specific enzymatic cleavage</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600051 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600051">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600014"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000681"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">gradient separation</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">the use of a sucrose gradient to isolate mitochondria</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">a protocol application that uses different concentrations of materials in a defined order to create a gradient to facilitate the separation of an input material into its components with specific qualities</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON:Kevin Clancy</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">gradient separation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600052 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600052">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600014"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000681"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">dialysis</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">the use of a dialysis bag of select pore size to remove salt from collagen isolated from mouse cartilage</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">a protocol application that uses diffusion through a semi-permeable membrane to separate an input material into two fractions of different composition</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON:Kevin Clancy</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">dialysis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600053 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600053">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600014"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000432"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000439"/>
</owl:unionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000681"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400140"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400142"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">electrophoresis</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Loading a mixture of proteins into a polyacrylamide gel and the application of an electrical current to the gel to separate the proteins by size and change.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">a protocol application that uses an electrical potential to move material through a defined matrix in order to separate it by its resistance to movement and its charge</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON:Kevin Clancy</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">Need to define more terms like gel_separation, matrix,centrifugation, and the connection between the force used to separate materials and the medium or barriers.</obo:IAO_0000232>
<rdfs:label xml:lang="en">electrophoresis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600054 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600054">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">selection by survival</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">The insertion of a gene for antibiotic resistance into a cell population and subsequent growth in the presence of the antibiotic to select for those cells which were successfully transfected</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">the use of environmental conditions to select for the organism or cells that have a certain trait</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON:Kevin Clancy</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">selection by survival</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600055 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600055">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600050"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33697"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">DNA cleavage, restriction analysis</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">the use of the restriction enzymes SalPI and PstI to cleave DNA into fragments, assay made up of components</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specific enzymatic cleavage of DNA molecules using endonucleases that cleave DNA molecules at specific sites based on the surrounding nucleotide sequence</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON:Kevin Clancy</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">restriction enzyme assay</obo:IAO_0000118>
<rdfs:label xml:lang="en">DNA restriction enzyme digestion</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600056 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600056">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000231"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/PR_000000001"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16670"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">protease cleavage</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">the use of trypsin to cleave pepsin into peptide fragments</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">protease cleavage is an enzymatic cleavage which relies on enzyme with protease activity to act on proteins and produce polypeptides (protein fragments).</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">enzymatic digestion</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">PlanAndPlannedProcess Branch</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">protease cleavage</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600057 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600057">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600058"/>
<obo:IAO_0000111 xml:lang="en">enzymatic DNA replication</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">the use of enzymes to duplicate DNA molecules</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">the use of enzymes to duplicate DNA molecule any process used to make additional copies of a biomaterial</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON:Kevin Clancy</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">enzymatic DNA replication</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600058 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600058">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000427"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000409"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">enzymatic amplification</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">the use of a polymerase chain reaction to amplify a fragment of DNA</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">the use of enzymes to increase the number of molecules of a biomaterial</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON:Kevin Clancy</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">enzymatic amplification</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600059 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600059">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600043"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10239"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">DNA transduction</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">The transfer of a recombinant bacterial plasmid into E.coli to facilitate amplification of a specific protein</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">a genetic transformation which relies on the use of lysogenic infection to transfer DNA sequences into an organism</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON:Kevin Clancy</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">DNA transduction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600060 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600060">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001152"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_16991"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000053"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000444"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">DNA transfection</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">The use of electroporation to permeabilize a cell membrane in order to introduce a plasmid encoding for a labeled protein of interest</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">a transfection which relies on the use of physical, electrical and chemical phenomena to introduce DNA into a cell</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON:Kevin Clancy</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">DNA transfection</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600063 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600063">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600064"/>
<obo:IAO_0000111 xml:lang="en">vector mediated expression</obo:IAO_0000111>
<obo:IAO_0000112>Construction of pRSS1327 expression vector by molecular cloning of a 1327-bp cDNA, which includes sequences of the entire coding region for RSS, into pBluescript. Expression in Escherichia coli of a functional, full-length RSS was confirmed by immunoblot analysis and enzymatic activity.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">vector mediated expression sis the generation of copies of biomaterial by in a cell_culture modified for this purpose by insertion of an expression vector</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">needs defined relationship to cell culture</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">PlanAndPlannedProcess Branch</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">vector mediated expression</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600064 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600064">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000411"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000737"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000416"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000731"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">recombinant vector cloning</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a planned process with the objective to insert genetic material into a cloning vector for future replication of the inserted material</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">pa_branch (Alan, Randi, Kevin, Jay, Bjoern)</obo:IAO_0000117>
<obo:IAO_0000118>molecular cloning</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<rdfs:label xml:lang="en">recombinant vector cloning</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600065 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600065">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_defined processes</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000121"/>
<obo:IAO_0000115 xml:lang="en">Place holder class, see editor note</obo:IAO_0000115>
<obo:IAO_0000117>PlanAndPlannedProcess Branch</obo:IAO_0000117>
<obo:IAO_0000119>OBI branch derived</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000226"/>
<rdfs:label>obsolete_defined processes</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0600067 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600067">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600038"/>
<obo:IAO_0000111 xml:lang="en">specific labeling</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">The addition of anti-CD8 antibody for an ICCS assay in order to selectively stain the CD8+ cells</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a labeling in which the labeling reagent used has a specificity to bind only certain components of the input material</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PlanAndPlannedProcess Branch</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">definition blessed by Allyson, Bjoern, Jay & Randi</obo:IAO_0000232>
<rdfs:label xml:lang="en">specific labeling</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0666666 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0666666">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0666667"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000880"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">RNA extraction</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A RNA extraction is a nucleic acid extraction where the desired output material is RNA</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PlanAndPlannedProcess Branch</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">requested by Helen Parkinson for MO</obo:IAO_0000232>
<rdfs:label xml:lang="en">RNA extraction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0666667 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0666667">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0302884"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000671"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100026"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100060"/>
</owl:unionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001010"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">nucleic acid extraction</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Phenol / chlorophorm extraction disolvation of protein content folllowed by ethanol precipitation of the nucleic acid fraction over night in the fridge followed by centrifugation to obtain a nucleic acid pellet.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">a material separation to recover the nucleic acid fraction of an input material</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PlanAndPlannedProcess Branch</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">requested by Helen Parkinson for MO. Could be defined class</obo:IAO_0000232>
<rdfs:label xml:lang="en">nucleic acid extraction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1000023 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1000023">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600029"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000079"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">cell culture supernatant</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">solution containing RPMI, fetal calf sera, antibiotics, and monoclonal antibody UCHT1.
Isolation of proliferation factor of immature T-cell clone in concanavalin A-stimulated splenocyte culture supernatant. Immunology. 2003 Jun;109(2):209-16. PMID: 12757615</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Supernatant of a cell culture is a material entity which contains media, supplements, and secreted products of the cells and becomes the environment of cultivated cell.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON: Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">GROUP: IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">cell culture supernatant</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1000024 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1000024">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0302886"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100060"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100067"/>
</owl:unionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">cell pellet</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Detection of fetal DNA in a cell pellet after centrifugation of mountant. J Forensic Sci. 2003 Jan;48(1):135-6. PMID: 12570214</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A material entity which results from the aggregation of cells produced by the application of centrifugal force to a liquid containing cells in suspension</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON: Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">GROUP: CEBS</obo:IAO_0000119>
<obo:IAO_0000119>GROUP: OBI Biomaterial Branch</obo:IAO_0000119>
<rdfs:label xml:lang="en">cell pellet</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1000029 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1000029">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000731"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600064"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000731"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">phage display library</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">PMID: 15905471.Nucleic Acids Res. 2005 May 19;33(9):e81.Oligonucleotide-assisted cleavage and ligation: a novel directional DNA cloning technology to capture cDNAs. Application in the construction of a human immune antibody phage-display library. [Phage display library encoding fragments of human antibodies. m-rna library encoding for 9-mer peptides]</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a phage display library is a collection of materials in which a mixture of genes or gene fragments is expressed and can be individually selected and amplified.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON: Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">PERSON: Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">display library</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">WEB: http://www.immuneepitope.org/home.do</obo:IAO_0000119>
<obo:IAO_0000232 xml:lang="en">PRS: 22022008. class moved under population,
modification of definition and replacement of biomaterials in previous definition with 'material'
addition of has_role restriction</obo:IAO_0000232>
<rdfs:label xml:lang="en">phage display library</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1000036 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1000036">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0302894"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">cell lysate</obo:IAO_0000111>
<obo:IAO_0000112>The effect of vaccination with the lysate of heat-shocked tumor cells on nitric oxide production in BALB/c mice with fibrosarcoma tumor. Cell Biol Int. 2008 Jul;32(7):835-40. PMID: 18455932</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">a cell lysate is a material entity which is output of a cell lysis process</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">PRS:22-02-2008: is a material which has output_role during lysis protocol-application.
old defintion: A mixture (collection) of cell components created by rupturing of the cell wall resulting from a lysis process</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">PERSON: Susanna Sansone</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">lysate</obo:IAO_0000118>
<obo:IAO_0000118>lysed material</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">GROUP: PSI</obo:IAO_0000119>
<rdfs:label xml:lang="en">cell lysate</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1000042 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1000042">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16670"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0302892"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">peptide construct</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Multiple Antigenic Peptide (MAP) construct containing T and B cell epitopes from p. falciparum congugated to a central glycin
A novel multivalent human CTL peptide construct elicits robust cellular immune responses in HLA-A*0201 transgenic mice: implications for HTLV-1 vaccine design. Vaccine. 2003 Jun 20;21(21-22):2767-81. PMID: 12798617</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">a material entity synthesized to contain a number of peptides conjugated together in a non-linear fashion</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON: Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">peptide construct</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1000048 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1000048">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0302859"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600043"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111 xml:lang="en">transgenic organism</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">HLA-A*0201 transgenic mice, Vaccinia virus expressing the LCMV gp protein
Possible ecological risks of transgenic organism release when transgenes affect mating success: sexual selection and the Trojan gene hypothesis. Proc Natl Acad Sci U S A. 1999 Nov 23;96(24):13853-6. PMID: 10570162</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a transgenic organism is material entity which derives from an organism which has been modified to express a gene not normally part of it</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">PRS:22-02-2008: is a organism which has output_role during genetic modification of type (KO) protocol-application</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">PERSON: Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">GROUP:IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">transgenic organism</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1000049 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1000049">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000680"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000953"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000341"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>whole mount tissue</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A whole organism preparation resulting from a histological preparation known as whole mount preparation where the whole specimen is mounted or spread on the microscope (glass) slide</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>whole mount sample</obo:IAO_0000118>
<obo:IAO_0000119>GROUP: OBI</obo:IAO_0000119>
<obo:IAO_0000232>PRS:22-02-2008: indicates the need to create a protocol application and distinguish it from this entity</obo:IAO_0000232>
<obo:IAO_0000232>PRS:22-02-2008: is a material which has output_role during whole mount preparation protocol-application</obo:IAO_0000232>
<rdfs:label>whole mount tissue</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1000207 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1000207">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
<obo:IAO_0000111 xml:lang="en">assay bead</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Dynabeads are commercially available magnetic beads which are precoated with antibodies specific for select cellular receptors and are used to separate cell populations.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A globular or round particle of defined physicochemical properties and size which can be exploited as either the primary substance for detection or as a secondary solid platform for the attachment of bioactive molecules.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">DS: Probably better modeled as a role.</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">OBI</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">bead</obo:IAO_0000118>
<rdfs:label xml:lang="en">assay bead</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110001 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110001">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000053"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110045"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000111>epitope</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A material entity with the disposition to be bound by an adaptive immune receptor.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">epitope</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110002 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110002">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_occurrence of disease</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An occurrence of disease is a process involving pathologic changes within an organism</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<rdfs:label>obsolete_occurrence of disease</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110003 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110003">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000925"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002220"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110026"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_1110026"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002220"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000925"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>host exposure to infectious agent</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a process in which an infectious agent comes into physical contact with a host organism.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">host exposure to infectious agent</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110007 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110007">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600007"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000319"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000925"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>administration in vivo with infectious agent</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">is an administration of an infectious agent to a host organism</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>administration in vivo with infectious agent</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110008 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110008">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110040"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000063"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_1110021"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110093"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110003"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>occurrence of infectious disease</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Is an occurrence of a disease caused by an infection</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">occurrence of infectious disease</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110010 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110010">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000016"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110011"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>disposition to cause an allergic reaction</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">The role borne by a material entity that is realized when it is recognized by the immune system and results in the occurrence of an allergic disease.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000118>allergenic disposition</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">disposition to cause an allergic reaction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110011 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110011">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110122"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110010"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>allergic reaction</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">an allergic reaction is an pathologic immune response by an organism to a non-self entity that is normally harmless(the allergen)</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">allergic reaction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110012 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110012">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110049"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000063"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110011"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>occurrence of allergy</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">The process of an allergic disease occurring in an organism.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">occurrence of allergy</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110013 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110013">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0600031"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0032623"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001445"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600031"/>
<obo:IAO_0000111>ELISPOT assay measuring epitope specific interleukin-2 production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An enzyme-linked immunospot assay that detects interleukin-2 production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>IL-2 release|ELISPOT</obo:OBI_9991118>
<rdfs:label>ELISPOT assay measuring epitope specific interleukin-2 production by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110014 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110014">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_1110045"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110119"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110022"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>epitope binding by adaptive immune receptor</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">is the process in which an adaptive immune receptor binds to a material entity (realizing its disposition). The binding affinity is significant enough to trigger an immune response. Specifically, transient non-specific binding of adaptive immune receptors occurring during immune surveillance is not considered significant binding.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">epitope binding by adaptive immune receptor</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110015 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110015">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110094"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>Immunization in vivo</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Process of administering an object playing the role of immunogen to a living organism</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">Immunization in vivo</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110016 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110016">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000084"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000236"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0042571"/>
</owl:unionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0002250"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>adaptive immune effector function</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A function realized as an immune response, which inheres in a T cell, B cell or antibody which derives from or is produced by a cell with prior antigen experience.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">adaptive immune effector function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110017 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110017">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110111"/>
<obo:IAO_0000111>living with infected household contact</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a process in which a a human being lives in the same household as another human being that is known to be infected with an infectious agent</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">living with infected household contact</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110018 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110018">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110111"/>
<obo:IAO_0000111>living in endemic area</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a process in which a potential host organism lives in a geographic area in which an infectious agent is present to such a degree of frequency that contact is likely</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">living in endemic area</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110019 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110019">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110111"/>
<obo:IAO_0000111>pathogen release in laboratory accident</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a process in which a an infectious agent maintained in a laboratory setting is not contained as planned, leading to potential exposure of human beings to the agent</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">pathogen release in laboratory accident</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110020 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110020">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110094"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100060"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100060"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>Immunization in vitro</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A planned process with the objective to administer an object playing the role of immunogen to a cell culture.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">Immunization in vitro</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110021 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110021">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110122"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110093"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IDO_0000586"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>infection process</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">the detrimental process in which an infectious agent colonizes or replicates in a host environment</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">infection process</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110022 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110022">
<owl:equivalentClass>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0019815"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0042101"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0042571"/>
</owl:unionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0032991"/>
<obo:IAO_0000111>adaptive immune receptor</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">is a receptor produced by cells of the adaptive immune system with the purpose of binding epitopes.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">adaptive immune receptor</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110023 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110023">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110082"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000111>immunogen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a material entity bearing the immunogen role</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">immunogen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110024 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110024">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0008150"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100026"/>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000925"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002220"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000925"/>
</owl:Restriction>
</owl:unionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110083"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110111"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>environmental exposure to infectious agent</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Is a process in which an infectious agent is in direct contact with a potential host organism in its habitat. This is preceded by proximity to the infectious agent</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">environmental exposure to infectious agent</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110026 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110026">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100026"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110083"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
<obo:IAO_0000111>host of immune response</obo:IAO_0000111>
<obo:IAO_0000112>A mouse that is vaccinated with a peptide and develops protective immunity. A human exposed to bacteria that are killed by pre-existing immune responses.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An organism in which an immune response process occurs.</obo:IAO_0000115>
<obo:IAO_0000116>In immune response processes in the context of infectious diseases and allergy, there are often multiple organisms involved, which requires calling out the 'host'. This terminology is expanded to allergy, cancer and transplantation.</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">host of immune response</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110028 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110028">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CLO_0009828"/>
<obo:IAO_0000111>293-T cell line</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A cell line derived from human embryonic kidney cells. This cell line contains the SV40 Large T-antigen, allowing episomal replication of transfected plasmids containing the SV40 origin of replication.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">http://www.biotech.ist.unige.it/cldb/cl5008.html</obo:IAO_0000119>
<rdfs:label xml:lang="en">293-T cell line</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110029 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110029">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CLO_0009828"/>
<obo:IAO_0000111>C1R cell line</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A cell line derived from human B cells. This cell line was created by EBV transformation (B-lymphoblastoid cell-line (BLCL)).</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">C1R cell line</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110030 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110030">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600000"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000319"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000925"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>experimental infection of cell culture</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">is the administration of an infectious agent to a cell culture with the objective to have the agent colonize and replicate in culture</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">experimental infection of cell culture</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110031 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110031">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CLO_0009828"/>
<obo:IAO_0000111>EL-4 cell line</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A cell line derived from mouse (C57BL/6N) lymphoma cells.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">http://www.biotech.ist.unige.it/cldb/cl1160.html</obo:IAO_0000119>
<rdfs:label xml:lang="en">EL-4 cell line</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110032 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110032">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CLO_0009828"/>
<obo:IAO_0000111>HeLa cell culture</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A cell line derived from human cervical cancer cells.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">http://www.biotech.ist.unige.it/cldb/cl1597.html</obo:IAO_0000119>
<rdfs:label xml:lang="en">HeLa cell line</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110033 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110033">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CLO_0009828"/>
<obo:IAO_0000111>JAWS II cell line</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A cell line derived from mouse dendritic cells.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">http://www.atcc.org/ATCCAdvancedCatalogSearch/ProductDetails/tabid/452/Default.aspx?ATCCNum=CRL-11904&Template=cellBiology</obo:IAO_0000119>
<rdfs:label xml:lang="en">JAWS II cell line</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110034 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110034">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000237"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000111>antigen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A material entity that has the antigen role.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">antigen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110035 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110035">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CLO_0009828"/>
<obo:IAO_0000111>Jurkat cell line</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A cell line derived from human T cells.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">http://www.biotech.ist.unige.it/cldb/cl5296.html</obo:IAO_0000119>
<rdfs:label xml:lang="en">Jurkat cell line</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110036 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110036">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CLO_0009828"/>
<obo:IAO_0000111>JY cell line</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">The JY cell line is an Epstein-Barr virus (EBV)-immortalised b cell lymphoblastoid line.(wikipedia)</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">JY cell line</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110037 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110037">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001181"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003128"/>
<obo:IAO_0000111>assay measuring binding of a T cell epitope:MHC:TCR complex</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A T cell epitope assay that measures the binding of T cell receptor to an epitope.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>T cell binding|any method</obo:OBI_9991118>
<rdfs:label>assay measuring binding of a T cell epitope:MHC:TCR complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110038 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110038">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CLO_0009828"/>
<obo:IAO_0000111>RMA cell line</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cell line derived from a mouse lymphoma, specifically a Rauscher virus-induced tumor.This cell ine is antigen processing-defective and expresses a very low level of MHC molecules on its surface.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">RMA cell line</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110039 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110039">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CLO_0009828"/>
<obo:IAO_0000111>T2 cell line</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A human T-B lymphoblastoid hybrid cell line</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">http://www.atcc.org/ATCCAdvancedCatalogSearch/ProductDetails/tabid/452/Default.aspx?ATCCNum=CRL-1992&Template=cellBiology</obo:IAO_0000119>
<rdfs:label xml:lang="en">T2 cell line</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110040 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110040">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000031"/>
<obo:IAO_0000111>infectious disease</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">is a disease caused by an infectious agent</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">infectious disease</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110041 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110041">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001468"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_1110046"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000029"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000953"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001468"/>
<obo:IAO_0000111>lymph node cell specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A cell specimen comprised of a mixed population of cells obtained by processing whole lymph node into individual cells, typically performed using a sieve. This population includes T cells, B cells, macrophages, and other cell types.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>lymph node cell specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110043 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110043">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100060"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000540"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0100060"/>
<obo:IAO_0000111>cultured adherent cell population</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A mixed cell population that is characterized by its ability to bind to tissue culture flasks or plates. This population typically contains macrophages and other cells capable of playing the antigen presenting cell role.</obo:IAO_0000115>
<obo:IAO_0000116>MHB 3-27-13: Following CLO alignment efforts, propose to update definition to read: "A cultured cell population comprised of cells that are able to grow attached to a solid substrate provided by tissue culture flasks or plates". The current definition seems to describe a more specific type of adherent culture of immunological origin as needed by IEDB.
MHB 3-5-13: Need to review axiom on this class in light of clarification that it refers to a cell line sample, and not an entire line. Not every population of adhernet cells is the output of an isolation process.</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000118>adherent cell culture sample</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">cultured adherent cell population</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110044 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110044">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001875"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000548"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001875"/>
<obo:IAO_0000111>cultured PBMC cell population</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A mixed cell population obtained by processing whole blood. The cells are characterized by having a similar density and are largely mononuclear cells (includes T cells, B cells, and other cell types).</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000118>PBMC cell culture sample</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">cultured PBMC cell population</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110045 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110045">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000016"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110014"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>disposition to be bound by an adaptive immune receptor</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Is the disposition borne by a material entity that is realized in a process of being bound by a adaptive immune receptor.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000118>epitope disposition</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">disposition to be bound by an adaptive immune receptor</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110046 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110046">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600014"/>
<obo:IAO_0000111>organ harvesting</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">The process of removing an organ from its source organism</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">organ harvesting</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110047 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110047">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001875"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000000"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000001018"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001875"/>
<obo:IAO_0000111>cultured CD3+ T cell population</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A T cell population characterized by expressing the CD3 molecule on its surface.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000118>CD3+ T cell culture sample</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">cultured CD3+ T cell population</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110048 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110048">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001875"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000000"/>
<owl:Class>
<owl:complementOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000001018"/>
</owl:Restriction>
</owl:complementOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001875"/>
<obo:IAO_0000111>cultured CD3- T cell population</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A T cell population characterized by not expressing the CD3 molecule on its surface.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000118>CD3- T cell culture sample</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">cultured CD3- T cell population</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110049 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110049">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000031"/>
<obo:IAO_0000111>allergy</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">is a disease in which an abnormally strong inflammatory immune response is triggered against non-self entities, and the immune response has no protective effect</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">allergy</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110050 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110050">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001875"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000000"/>
<owl:Class>
<owl:complementOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000001004"/>
</owl:Restriction>
</owl:complementOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001875"/>
<obo:IAO_0000111>cultured CD4- T cell population</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A T cell population characterized by not expressing the CD4 molecule on its surface.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000118>CD4- T cell culture sample</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">cultured CD4- T cell population</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110051 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110051">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001875"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000000"/>
<owl:Class>
<owl:complementOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000025402"/>
</owl:Restriction>
</owl:complementOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001875"/>
<obo:IAO_0000111>cultured CD8- T cell population</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A T cell population characterized by not expressing the CD8 molecule on its surface.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000118>CD8- T cell culture sample</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">cultured CD8- T cell population</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110052 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110052">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001875"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000000"/>
<owl:Class>
<owl:complementOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000001004"/>
</owl:Restriction>
</owl:complementOf>
</owl:Class>
<owl:Class>
<owl:complementOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000025402"/>
</owl:Restriction>
</owl:complementOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110050"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110051"/>
<obo:IAO_0000111>cultured CD4-/CD8- T cell population</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A T cell population characterized by not expressing the CD4 nor the CD8 molecule on its surface.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000118>CD4-/CD8- T cell culture sample</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">cultured CD4-/CD8- T cell population</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110053 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110053">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000031"/>
<obo:IAO_0000111>cancer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A disease characterized by abnormal and uncontrolled cell division</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">cancer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110054 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110054">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000031"/>
<obo:IAO_0000111>autoimmune disease</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Is a disease characterized by an immune response of an organism against parts of itself</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">autoimmune disease</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110055 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110055">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete_disease</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000121"/>
<obo:IAO_0000115 xml:lang="en">placeholder to be imported from disease ontology</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000031"/>
<rdfs:label>obsolete_disease</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110056 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110056">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0032623"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0032623"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001193"/>
<obo:IAO_0000111>epitope specific IL-2 release by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A biological process where T cells produce IL-2 resulting from the recognition of a T cell epitope.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">epitope specific IL-2 release by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110057 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110057">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001588"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110014"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_1110045"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110119"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0042101"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110119"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0042611"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_1110086"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0042611"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>MHC:epitope complex binding to TCR</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a process of an MHC molecule binding to an entity playing the role of epitope to create an MHC:epitope complex which is then bound by a TCR molecule.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">MHC:epitope complex binding to TCR</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110059 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110059">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0600031"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0032609"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001414"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600031"/>
<obo:IAO_0000111>ELISPOT assay measuring epitope specific interferon-gamma production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An enzyme-linked immunospot assay that detects interferon-gamma production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>IFNg release|ELISPOT</obo:OBI_9991118>
<rdfs:label>ELISPOT assay measuring epitope specific interferon-gamma production by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110061 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110061">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>exposure resulting in immune reactivity</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a process in which an organism (host) is exposed to some material entity, which results in an immune reactivity</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">exposure resulting in immune reactivity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110082 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110082">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<obo:IAO_0000111>immunogen role</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A role of a material entity that is realized when the material elicits an immune response targeting itself in whole or in part.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">immunogen role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110083 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110083">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:allValuesFrom>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0006955"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_1110015"/>
</owl:unionOf>
</owl:Class>
</owl:allValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>host of immune response role</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">is a role borne by an organism. It is realized by the organism during an immunization or an immune response taking place inside or on the surface of the organism, and in which the responding or stimulated immune system is part of the host.</obo:IAO_0000115>
<obo:IAO_0000116>03/21/2010: This sense of 'host' is used not only in infectious diseases but also allergy, cancer, transplantation, etc. which is why it is needed separately from the 'host of infectious agent' meaning, which will be imported from IDO.</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">host of immune response role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110084 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110084">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110016"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000084"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:allValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0002250"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:allValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>effector T cell function</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">The function inhering in a T cell that is realized in an immune response that results from the T cell receptor binding to the MHC:epitope complex.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">effector T cell function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110085 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110085">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000000"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0042611"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>antigen presentation function</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a function inhering in a cell that expresses MHC molecules which is realized in the process of antigen processing and presentation of antigen derived parts by MHC molecules on the cell surface.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">APC</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<obo:IAO_0000232>should add a reference to the antigen processing and presentation process.</obo:IAO_0000232>
<rdfs:label xml:lang="en">antigen presentation function</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110086 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110086">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<obo:IAO_0000111>restricting MHC role</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">The role played by an MHC molecule by binding a material entity playing the role of epitope when that epitope/MHC molecule pair are recognized (bound) by a TCR molecule on the surface of a cell playing the role of effector cell.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">restricting MHC role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110087 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110087">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<obo:IAO_0000111>donor</obo:IAO_0000111>
<obo:IAO_0000112>A T cell line from a PPD(+) donor.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A role which inheres in an organism or part thereof from which any part including cell, organ or tissue is removed with the intention that the donated part will be placed into another organism and/or cultured in vitro.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000118>donor role</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<obo:IAO_0000232>Definition modified by HP to deal with the case where an organ may be removed for donation but is not transplanted as intended.</obo:IAO_0000232>
<rdfs:label xml:lang="en">donor role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110091 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110091">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<obo:IAO_0000111>immune epitope carrier role</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A role inhering in a material entity that is covalently bound to an epitope in order to increase the epitopes immunogenicity.</obo:IAO_0000115>
<obo:IAO_0000116>03/21/2010, BP: surveying the literature, this seems to be a messy term. Need to clarify what material entities can be carriers, and if only immunogenicity (not antigenicity) is effected by their presence.</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">immune epitope carrier role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110092 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110092">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>adjuvant role</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Adjuvant role is a role that inheres in a material entity and which is realized through a process of modifying a biological response.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000118>adjuvent role</obo:IAO_0000118>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">adjuvant role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110093 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110093">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000016"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110021"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>disposition to infect an organism</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Is a role borne by an agent, and realized when in contact with or inside another organism in which it is capable of replicating and causing disease</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">disposition to infect an organism</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110094 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110094">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0008150"/>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_1110001"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110023"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_1110001"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110023"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:unionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110014"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110082"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000084"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000236"/>
</owl:unionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110016"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>immunization</obo:IAO_0000111>
<obo:IAO_0000112>Infection with influenza (the immunogen) leading to B cells producing antibodies (the effector function) against surface regions of the HA protein (the epitope).</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">The process of an epitope that is part of or derived from an immunogen coming into contact with adaptive immune cells resulting in these cells acquiring immune effector functions specific for the epitope.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">immunization</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110095 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110095">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600014"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000655"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>blood harvesting</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A material separation where blood is taken from an organism.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">blood harvesting</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110099 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110099">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CLO_0009828"/>
<obo:IAO_0000111>L cell line</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A cell line derived from mouse fibroblasts.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">http://www.biotech.ist.unige.it/cldb/cl3075.html</obo:IAO_0000119>
<rdfs:label xml:lang="en">L cell line</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110106 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110106">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001875"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000000"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110085"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001875"/>
<obo:IAO_0000111>cultured antigen presenting cell population</obo:IAO_0000111>
<obo:IAO_0000112>A culture of PBMCs. A culture of Hela cells.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a cell culture including cells that have an antigen presentation function</obo:IAO_0000115>
<obo:IAO_0000118>antigen presenting cell culture sample</obo:IAO_0000118>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>cultured antigen presenting cell population</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110107 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110107">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001875"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000084"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110084"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001875"/>
<obo:IAO_0000111>cultured effector T cell population</obo:IAO_0000111>
<obo:IAO_0000112>A culture of cytotoxic CD8+ T cells.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cell culture including cells that have an effector T cell function</obo:IAO_0000115>
<obo:IAO_0000118>culture of effector T cells</obo:IAO_0000118>
<obo:IAO_0000118>effector T cell culture sample</obo:IAO_0000118>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>cultured effector T cell population</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110108 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110108">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000319"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000111>material to be added</obo:IAO_0000111>
<obo:IAO_0000112>A mixture of peptides that is being added into a cell culture.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A material entity that is added to another material entity in an “adding a material entity into a target” process.</obo:IAO_0000115>
<obo:IAO_0000116>10/26/09: This defined class is used as a 'macro expression' to reduce the size of the IEDB export</obo:IAO_0000116>
<obo:IAO_0000116>2010/02/24 Alan Ruttenberg: I think this might generate confusion as the common use of the term would consider something to be a specimen during the realization of the role, not only if it bears it. However having this class as a probe, or for display, or as a macro might be useful. Ideally we would mark or segregate such classes</obo:IAO_0000116>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>material to be added</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110109 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110109">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000444"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000111>target of material addition</obo:IAO_0000111>
<obo:IAO_0000112>A cell culture into which a mixture of peptides is being added.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A material entity that receives the addition of another material entity in an “adding a material entity into a target” process.</obo:IAO_0000115>
<obo:IAO_0000116>10/26/09: This defined class is used as a 'macro' to reduce the size of the IEDB export.</obo:IAO_0000116>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>target of material addition</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110111 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110111">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>environmental proximity to infectious agent</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">Is a process in which an infectious agent comes close enough to a potential host organism in its habitat that a contact can result</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">environmental proximity to infectious agent</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110114 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110114">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110111"/>
<obo:IAO_0000111>contact to pathogen carrying biological vector</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a process in which a vector carrying an infectious agent comes close enough to a potential host organism that a contact can result</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">contact to pathogen carrying biological vector</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110116 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110116">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001468"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_1110046"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002106"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000953"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001468"/>
<obo:IAO_0000111>splenocyte specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cell specimen comprised of a mixed cell population obtained by processing whole spleen into individual cells, typically performed using a sieve or blender. This population includes T cells, B cells, macrophages, and other cell types.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>splenocyte specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110118 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110118">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CLO_0009828"/>
<obo:IAO_0000111>P815 cell line</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A cell line derived from mouse mastocytoma.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<obo:IAO_0000119 xml:lang="en">http://www.biotech.ist.unige.it/cldb/cl5244.html</obo:IAO_0000119>
<rdfs:label xml:lang="en">P815 cell line</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110120 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110120">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000237"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>assay antigen role</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An antigen role that is realized as part of an assay, where immune recognition of the material with the assay antigen role is being detected as part of the assay.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">assay antigen role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110122 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110122">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>pathologic process</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">abnormal, harmful processes caused by or associated with a disease</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">pathologic process</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110124 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110124">
<owl:equivalentClass>
<owl:Class>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0003141"/>
</owl:Restriction>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110037"/>
<obo:IAO_0000111>assay measuring qualitative binding of a T cell epitope:MHC:TCR complex</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that detects the binding of a MHC:epitope complex with a T cell receptor, and produces a qualitative measurement of the binding as an output.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>qualitative binding|binding assay</obo:OBI_9991118>
<rdfs:label>assay measuring qualitative binding of a T cell epitope:MHC:TCR complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110125 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110125">
<owl:equivalentClass>
<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000000"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0042611"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
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<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001503"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0019882"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002075"/>
<obo:IAO_0000111>assay measuring MHC ligand processing and presentation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A MHC ligand assay that determines what ligands are processed and loaded onto MHC molecules by eluting ligands and identifying them.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>ligand presentation|any method</obo:OBI_9991118>
<rdfs:label>assay measuring MHC ligand processing and presentation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110126 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110126">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001181"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001503"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002075"/>
<obo:IAO_0000111>assay measuring binding of a MHC:ligand complex</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A MHC ligand assay that detects the binding of a ligand to an MHC molecule.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>MHC binding|any method</obo:OBI_9991118>
<rdfs:label>assay measuring binding of a MHC:ligand complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110127 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110127">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001181"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001702"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003127"/>
<obo:IAO_0000111>assay measuring binding of a B cell epitope:antibody complex</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A B cell epitope assay that measures the binding of an antibody receptor to an epitope.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>antibody binding|any method</obo:OBI_9991118>
<rdfs:label>assay measuring binding of a B cell epitope:antibody complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110128 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110128">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001503"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003121"/>
</owl:unionOf>
</owl:Class>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001702"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003119"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001702"/>
</owl:Restriction>
</owl:unionOf>
</owl:Class>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003120"/>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
</owl:Restriction>
</owl:unionOf>
</owl:Class>
</owl:unionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>immune epitope assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that detects the binding of an epitope to an adaptive immune receptor, or an immune process resulting from such a binding event, or characterizes the structrue of the complex resulting from such a binding event.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>immune epitope assay</obo:OBI_9991118>
<rdfs:label>immune epitope assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110129 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110129">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0001816"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002055"/>
<obo:IAO_0000111>assay measuring epitope specific cytokine production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A T cell epitope assay that detects cytokine production by T cells.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>cytokine release|biological activity</obo:OBI_9991118>
<rdfs:label>assay measuring epitope specific cytokine production by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110130 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110130">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000882"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0001913"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000882"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002055"/>
<obo:IAO_0000111>assay measuring epitope specific T cell killing</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A T cell epitope dependent biological activity assay that detects the killing of an antigen presenting cell (APC) by a T cell whose TCR recognizes an epitope presented by the APC.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>cytotoxicity|biological activity</obo:OBI_9991118>
<rdfs:label>assay measuring epitope specific T cell killing</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110131 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110131">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
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<owl:Class>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0042098"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
</owl:Restriction>
</owl:intersectionOf>
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</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002055"/>
<obo:IAO_0000111>assay measuring epitope specific proliferation of T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A T cell epitope dependent biological activity assay that detects T cell proliferation.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>proliferation|biological activity</obo:OBI_9991118>
<rdfs:label>assay measuring epitope specific proliferation of T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110132 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110132">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000111>obsolete CD8 receptor</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A transmembrane glycoprotein that serves as a co-receptor for the T cell receptor.</obo:IAO_0000115>
<obo:IAO_0000118>CD8</obo:IAO_0000118>
<obo:IAO_0000234>https://github.com/obi-ontology/obi/issues/353</obo:IAO_0000234>
<obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/PR_000025402"/>
<rdfs:label>obsolete CD8 receptor</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110150 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110150">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0003385"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001876"/>
</owl:Restriction>
</owl:someValuesFrom>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002062"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_9999994"/>
<obo:IAO_0000111>51 chromium assay measuring epitope specific T cell killing</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A chromium release assay that detects the killing of an antigen presenting cell (APC) by a T cell whose TCR recognizes an epitope presented by the APC.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:OBI_9991118>cytotoxicity|51 chromium</obo:OBI_9991118>
<rdfs:label>51 chromium assay measuring epitope specific T cell killing</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_1110151 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110151">
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001414"/>
<obo:IAO_0000111>ELISA measuring epitope specific interferon-gamma production by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An enzyme-linked immunosorbent assay that detects interferon-gamma production by T cells.</obo:IAO_0000115>
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<obo:IAO_0000115 xml:lang="en">A tritiated thymidine incorporation assay that detects T cell epitope specific proliferation in vitro.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
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<obo:IAO_0000115 xml:lang="en">A BrdU incorporation assay that detects T cell epitope specific proliferation in vitro.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
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<obo:IAO_0000115 xml:lang="en">A biological process where T cells proliferate resulting from the recognition of a T cell epitope.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
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<obo:IAO_0000115 xml:lang="en">A biological process where T cells produce GM-CSF resulting from the recognition of a T cell epitope.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
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<!-- http://purl.obolibrary.org/obo/OBI_1110185 -->
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<obo:IAO_0000115 xml:lang="en">A biological process where T cells produce IFNg resulting from the recognition of a T cell epitope.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
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<!-- http://purl.obolibrary.org/obo/OBI_1110187 -->
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<obo:IAO_0000115 xml:lang="en">A biological process where T cells produce IL-10 resulting from the recognition of a T cell epitope.</obo:IAO_0000115>
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<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
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<!-- http://purl.obolibrary.org/obo/OBI_1110193 -->
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<obo:IAO_0000115 xml:lang="en">A biological process where T cells produce IL-17 resulting from the recognition of a T cell epitope.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
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<!-- http://purl.obolibrary.org/obo/OBI_1110195 -->
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<!-- http://purl.obolibrary.org/obo/OBI_1110196 -->
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<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
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<!-- http://purl.obolibrary.org/obo/OBI_1110199 -->
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<obo:IAO_0000115 xml:lang="en">A biological process where T cells produce IL-4 resulting from the recognition of a T cell epitope.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
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<!-- http://purl.obolibrary.org/obo/OBI_1110201 -->
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<obo:IAO_0000111>allergen</obo:IAO_0000111>
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<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A material entity bearing the disposition to cause an allergic reaction</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
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<!-- http://purl.obolibrary.org/obo/OBI_1110202 -->
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<obo:IAO_0000115 xml:lang="en">A biological process where T cells produce IL-5 resulting from the recognition of a T cell epitope.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">epitope specific IL-5 release by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110203 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110203">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0032635"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0032635"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001193"/>
<obo:IAO_0000111>epitope specific IL-6 release by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A biological process where T cells produce IL-6 resulting from the recognition of a T cell epitope.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">epitope specific IL-6 release by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110204 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110204">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0001913"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0001913"/>
<obo:IAO_0000111>epitope specific killing by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A biological process where T cells lyse antigen presenting cells resulting from the recognition of a T cell epitope on MHC molecules of the antigen presenting cell.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">epitope specific killing by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110206 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110206">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0032640"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_1110060"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_1110057"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0032640"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001351"/>
<obo:IAO_0000111>epitope specific TNF release by T cells</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A biological process where T cells produce TNF resulting from the recognition of a T cell epitope.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
<rdfs:label xml:lang="en">epitope specific TNF release by T cells</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110207 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110207">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000109"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0032609"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>assay detecting IFN-gamma production</obo:IAO_0000111>
<obo:IAO_0000112>An IFN-g ELISPOT is an assay detecting ifn-gamma production</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An assay that determines information about the production of the cytokine interferon gamma</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000118>IFNg release</obo:IAO_0000118>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>assay detecting IFN-gamma production</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1110300 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110300">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000088"/>
<obo:IAO_0000111>direct submission to IEDB</obo:IAO_0000111>
<obo:IAO_0000112>The report on "Identification of a dominant CD4 T cell epitope in the membrane lipoprotein Tul4 from Francisella tularensis LVS. " submitted by Valentino et al to the IEDB.
The content of that report on the IEDB website is here: http://iedb.org/refId/1013357</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A report about experiments in an investigation that characterize immune epitopes, and was submitted directly by the authors to the Immune Epitope Database (IEDB)</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<rdfs:label>direct submission to IEDB</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_1200000 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1200000">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000950"/>
<obo:IAO_0000111>FFPE specimen</obo:IAO_0000111>
<obo:IAO_0000112>Many of today’s researchers prefer to use Formalin-Fixed Paraffin-Embedded samples of tissues for their IHC, histological or in-situ genomic analyses. Professionally fixed and embedded FFPE samples and the biomolecules they contain are reasonably stable at ambient temperatures. -based on https://lab-ally.com/histopathology-resources/ffpe-samples/</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen that has been fixed in formalin and embedded in paraffin.</obo:IAO_0000115>
<obo:IAO_0000117>MIABIS</obo:IAO_0000117>
<obo:IAO_0000118>formalin-fixed paraffin-embeded specimen</obo:IAO_0000118>
<obo:IAO_0000119>https://www.biochain.com/general/what-is-ffpe-tissue/</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1019</obo:IAO_0000233>
<rdfs:label>FFPE specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2000000 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2000000">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002553"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000002"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002553"/>
<obo:IAO_0000111>uterine cervix specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from some uterine cervix</obo:IAO_0000115>
<obo:IAO_0000117>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000117>Mark A. Miller ORCID:0000-0001-9076-6066</obo:IAO_0000117>
<obo:IAO_0000119>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000119>
<obo:IAO_0000119>Mark A. Miller ORCID:0000-0001-9076-6066</obo:IAO_0000119>
<rdfs:label>uterine cervix specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2000001 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2000001">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000057"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>urethra specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from some urethra</obo:IAO_0000115>
<obo:IAO_0000117>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000117>Mark A. Miller ORCID:0000-0001-9076-6066</obo:IAO_0000117>
<obo:IAO_0000119>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000119>
<obo:IAO_0000119>Mark A. Miller ORCID:0000-0001-9076-6066</obo:IAO_0000119>
<rdfs:label>urethra specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2000002 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2000002">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000316"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2000009"/>
<obo:IAO_0000111>cervical mucus specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from some cervical mucus</obo:IAO_0000115>
<obo:IAO_0000117>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000117>Mark A. Miller ORCID:0000-0001-9076-6066</obo:IAO_0000117>
<obo:IAO_0000119>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000119>
<obo:IAO_0000119>Mark A. Miller ORCID:0000-0001-9076-6066</obo:IAO_0000119>
<rdfs:label>cervical mucus specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2000003 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2000003">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000341"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>throat specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from some throat</obo:IAO_0000115>
<obo:IAO_0000117>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000117>Mark A. Miller ORCID:0000-0001-9076-6066</obo:IAO_0000117>
<obo:IAO_0000119>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000119>
<obo:IAO_0000119>Mark A. Miller ORCID:0000-0001-9076-6066</obo:IAO_0000119>
<rdfs:label>throat specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2000004 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2000004">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000970"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>eye specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from some eye</obo:IAO_0000115>
<obo:IAO_0000117>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000117>Mark A. Miller ORCID:0000-0001-9076-6066</obo:IAO_0000117>
<obo:IAO_0000119>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000119>
<obo:IAO_0000119>Mark A. Miller ORCID:0000-0001-9076-6066</obo:IAO_0000119>
<rdfs:label>eye specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2000005 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2000005">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001004"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>respiratory system specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from some respiratory system</obo:IAO_0000115>
<obo:IAO_0000117>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000117>Mark A. Miller ORCID:0000-0001-9076-6066</obo:IAO_0000117>
<obo:IAO_0000119>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000119>
<obo:IAO_0000119>Mark A. Miller ORCID:0000-0001-9076-6066</obo:IAO_0000119>
<rdfs:label>respiratory system specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2000006 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2000006">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_2000005"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001557"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2000005"/>
<obo:IAO_0000111>upper respiratory tract specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from some upper respiratory tract</obo:IAO_0000115>
<obo:IAO_0000117>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000117>Mark A. Miller ORCID:0000-0001-9076-6066</obo:IAO_0000117>
<obo:IAO_0000119>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000119>
<obo:IAO_0000119>Mark A. Miller ORCID:0000-0001-9076-6066</obo:IAO_0000119>
<rdfs:label>upper respiratory tract specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2000007 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2000007">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_2000006"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001728"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2000006"/>
<obo:IAO_0000111>nasopharynx specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from some nasopharynx</obo:IAO_0000115>
<obo:IAO_0000117>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000117>Mark A. Miller ORCID:0000-0001-9076-6066</obo:IAO_0000117>
<obo:IAO_0000119>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000119>
<obo:IAO_0000119>Mark A. Miller ORCID:0000-0001-9076-6066</obo:IAO_0000119>
<rdfs:label>nasopharynx specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2000008 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2000008">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_2000009"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001968"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2000009"/>
<obo:IAO_0000111>semen specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from some semen</obo:IAO_0000115>
<obo:IAO_0000117>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000117>Mark A. Miller ORCID:0000-0001-9076-6066</obo:IAO_0000117>
<obo:IAO_0000119>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000119>
<obo:IAO_0000119>Mark A. Miller ORCID:0000-0001-9076-6066</obo:IAO_0000119>
<rdfs:label>semen specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2000009 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2000009">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001479"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0006314"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001479"/>
<obo:IAO_0000111>bodily fluid specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from some bodily fluid</obo:IAO_0000115>
<obo:IAO_0000117>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000117>Mark A. Miller ORCID:0000-0001-9076-6066</obo:IAO_0000117>
<obo:IAO_0000119>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000119>
<obo:IAO_0000119>Mark A. Miller ORCID:0000-0001-9076-6066</obo:IAO_0000119>
<rdfs:label>bodily fluid specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2000010 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2000010">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002513"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0007106"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002513"/>
<obo:IAO_0000111>chorionic villus specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from some chorionic villus</obo:IAO_0000115>
<obo:IAO_0000117>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000117>Mark A. Miller ORCID:0000-0001-9076-6066</obo:IAO_0000117>
<obo:IAO_0000119>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000119>
<obo:IAO_0000119>Mark A. Miller ORCID:0000-0001-9076-6066</obo:IAO_0000119>
<rdfs:label>chorionic villus specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2000011 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2000011">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002503"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0007109"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0002503"/>
<obo:IAO_0000111>meconium specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from some meconium</obo:IAO_0000115>
<obo:IAO_0000117>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000117>Mark A. Miller ORCID:0000-0001-9076-6066</obo:IAO_0000117>
<obo:IAO_0000119>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000119>
<obo:IAO_0000119>Mark A. Miller ORCID:0000-0001-9076-6066</obo:IAO_0000119>
<rdfs:label>meconium specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2000012 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2000012">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000655"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0012168"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2000013"/>
<obo:IAO_0000111>umbilical cord blood specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from some umbilical cord blood</obo:IAO_0000115>
<obo:IAO_0000117>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000117>Mark A. Miller ORCID:0000-0001-9076-6066</obo:IAO_0000117>
<obo:IAO_0000119>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000119>
<obo:IAO_0000119>Mark A. Miller ORCID:0000-0001-9076-6066</obo:IAO_0000119>
<rdfs:label>umbilical cord blood specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2000013 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2000013">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000655"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0013755"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000655"/>
<obo:IAO_0000111>arterial blood specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from some arterial blood</obo:IAO_0000115>
<obo:IAO_0000117>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000117>Mark A. Miller ORCID:0000-0001-9076-6066</obo:IAO_0000117>
<obo:IAO_0000119>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000119>
<obo:IAO_0000119>Mark A. Miller ORCID:0000-0001-9076-6066</obo:IAO_0000119>
<rdfs:label>arterial blood specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2000014 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2000014">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000655"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0013756"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000655"/>
<obo:IAO_0000111>venous blood specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from some venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000117>Mark A. Miller ORCID:0000-0001-9076-6066</obo:IAO_0000117>
<obo:IAO_0000119>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000119>
<obo:IAO_0000119>Mark A. Miller ORCID:0000-0001-9076-6066</obo:IAO_0000119>
<rdfs:label>venous blood specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2000015 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2000015">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000655"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000659"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001000"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0013757"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000655"/>
<obo:IAO_0000111>capillary blood specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from some capillary blood</obo:IAO_0000115>
<obo:IAO_0000117>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000117>Mark A. Miller ORCID:0000-0001-9076-6066</obo:IAO_0000117>
<obo:IAO_0000119>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000119>
<obo:IAO_0000119>Mark A. Miller ORCID:0000-0001-9076-6066</obo:IAO_0000119>
<rdfs:label>capillary blood specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2000016 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2000016">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001468"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000659"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000232"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001468"/>
<obo:IAO_0000111>erythrocyte specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from some erythrocytes</obo:IAO_0000115>
<obo:IAO_0000117>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000117>Mark A. Miller ORCID:0000-0001-9076-6066</obo:IAO_0000117>
<obo:IAO_0000119>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000119>
<obo:IAO_0000119>Mark A. Miller ORCID:0000-0001-9076-6066</obo:IAO_0000119>
<rdfs:label>erythrocyte specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2000017 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2000017">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001468"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000659"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000558"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001468"/>
<obo:IAO_0000111>reticulocyte specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from some reticulocytes</obo:IAO_0000115>
<obo:IAO_0000117>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000117>Mark A. Miller ORCID:0000-0001-9076-6066</obo:IAO_0000117>
<obo:IAO_0000119>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000119>
<obo:IAO_0000119>Mark A. Miller ORCID:0000-0001-9076-6066</obo:IAO_0000119>
<rdfs:label>reticulocyte specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2000018 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2000018">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001468"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0600005"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000659"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000738"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001468"/>
<obo:IAO_0000111>leukocyte specimen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from some leukocytes</obo:IAO_0000115>
<obo:IAO_0000117>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000117>Mark A. Miller ORCID:0000-0001-9076-6066</obo:IAO_0000117>
<obo:IAO_0000119>Christian Stoeckert ORCID:0000-0002-5714-991X</obo:IAO_0000119>
<obo:IAO_0000119>Mark A. Miller ORCID:0000-0001-9076-6066</obo:IAO_0000119>
<rdfs:label>leukocyte specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100001 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100001">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16526"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16526"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<obo:IAO_0000111>carbon dioxide assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of carbon dioxide</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>carbon dioxide assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100002 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100002">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_29101"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_29101"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<obo:IAO_0000111>sodium(1+) assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of sodium(1+)</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>sodium(1+) assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100003 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100003">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16737"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16737"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<obo:IAO_0000111>creatinine assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of creatinine</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>creatinine assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100004 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100004">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_29103"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_29103"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<obo:IAO_0000111>potassium(1+) assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of potassium(1+)</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>potassium(1+) assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100005 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100005">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003021"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000767"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>basophil count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of basophils</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>basophil count assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100006 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100006">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003022"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000775"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>neutrophil count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of neutrophils</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>neutrophil count assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100007 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100007">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003023"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000771"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>eosinophil count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of eosinophils</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>eosinophil count assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100008 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100008">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003024"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000542"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>lymphocyte count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of lymphocytes</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>lymphocyte count assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100009 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100009">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003025"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000576"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>monocyte count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of monocytes</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>monocyte count assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100010 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100010">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17996"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17996"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<obo:IAO_0000111>chloride assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of chloride</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>chloride assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100011 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100011">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003018"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000232"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>erythrocyte count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of erythrocytes</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>erythrocyte count assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100012 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100012">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003028"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000233"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>platelet count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of platelets</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>platelet count assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100013 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100013">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001977"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000738"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>leukocyte count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of leukocytes</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>leukocyte count assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100014 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100014">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35143"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35143"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<obo:IAO_0000111>hemoglobin assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of hemoglobin</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>hemoglobin assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100015 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100015">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35780"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35780"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<obo:IAO_0000111>phosphate ion assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of phosphate ion</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>phosphate ion assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100016 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100016">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000050219"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000050219"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100023"/>
<obo:IAO_0000111>alanine aminotransferase assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of alanine aminotransferase</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>alanine aminotransferase assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100017 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100017">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000050343"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000050343"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100023"/>
<obo:IAO_0000111>alkaline phosphatase (human) assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of alkaline phosphatase (human)</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>alkaline phosphatase (human) assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100018 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100018">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16990"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16990"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<obo:IAO_0000111>bilirubin IXalpha assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of bilirubin IXalpha</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>bilirubin IXalpha assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100019 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100019">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000050353"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000050353"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100023"/>
<obo:IAO_0000111>aspartate aminotransferase (human) assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of aspartate aminotransferase (human)</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>aspartate aminotransferase (human) assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100020 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100020">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17234"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17234"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<obo:IAO_0000111>glucose assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of glucose</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>glucose assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100021 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100021">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_39127"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_39127"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<obo:IAO_0000111>magnesium cation assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of magnesium cation</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>magnesium cation assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100022 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100022">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000003918"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000003918"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100023"/>
<obo:IAO_0000111>albumin assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of albumin</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>albumin assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100023 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100023">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<obo:IAO_0000111>protein assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of protein</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>protein assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100024 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100024">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_39123"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_39123"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003012"/>
<obo:IAO_0000111>calcium cation assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of calcium cation</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>calcium cation assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100025 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100025">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000029971"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000029971"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100023"/>
<obo:IAO_0000111>creatine kinase assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of creatine kinase</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>creatine kinase assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100026 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100026">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003018"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000562"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>nucleate erythrocyte count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of nucleate erythrocytes</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>nucleate erythrocyte count assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100027 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100027">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003022"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0011114"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>segmented neutrophil of bone marrow count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of segmented neutrophil of bone marrows</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>segmented neutrophil of bone marrow count assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100028 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100028">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000050331"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>lactate dehydrogenase complex assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures lactate dehydrogenase complex</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>lactate dehydrogenase complex assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100029 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100029">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17855"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17855"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<obo:IAO_0000111>triglyceride assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of triglyceride</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>triglyceride assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100030 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100030">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_47775"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_47775"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<obo:IAO_0000111>high-density lipoprotein cholesterol assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of high-density lipoprotein cholesterol</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>high-density lipoprotein cholesterol assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100031 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100031">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16113"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16113"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<obo:IAO_0000111>cholesterol assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of cholesterol</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>cholesterol assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100032 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100032">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_47774"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_47774"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<obo:IAO_0000111>low-density lipoprotein cholesterol assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of low-density lipoprotein cholesterol</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>low-density lipoprotein cholesterol assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100033 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100033">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_81567"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_81567"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<obo:IAO_0000111>thyroid stimulating hormone assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of thyroid stimulating hormone</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>thyroid stimulating hormone assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100034 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100034">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000003015"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000003015"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100023"/>
<obo:IAO_0000111>prostate-specific antigen assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of prostate-specific antigen</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>prostate-specific antigen assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100035 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100035">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_30660"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_30660"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<obo:IAO_0000111>thyroxine assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of thyroxine</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>thyroxine assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100036 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100036">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33262"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33262"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<obo:IAO_0000111>elemental oxygen assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of elemental oxygen</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>elemental oxygen assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100037 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100037">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_37445"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_37445"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<obo:IAO_0000111>folic acids assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of folic acids</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>folic acids assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100038 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100038">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003026"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000558"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>reticulocyte count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of reticulocytes</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>reticulocyte count assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100039 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100039">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0002027"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>osmolality assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures osmolality</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>osmolality assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100040 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100040">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17423"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17423"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<obo:IAO_0000111>methemoglobin assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of methemoglobin</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>methemoglobin assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100041 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100041">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000027247"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>cytosolic creatine kinase complex, MB-type assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures cytosolic creatine kinase complex, MB-type</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>cytosolic creatine kinase complex, MB-type assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100042 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100042">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_28358"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
<obo:IAO_0000111>rac-lactic acid assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures rac-lactic acid</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>rac-lactic acid assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100043 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100043">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17544"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17544"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<obo:IAO_0000111>hydrogencarbonate assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of hydrogencarbonate</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>hydrogencarbonate assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100044 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100044">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_28001"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_28001"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<obo:IAO_0000111>vancomycin assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of vancomycin</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>vancomycin assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100045 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100045">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_28864"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_28864"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<obo:IAO_0000111>tobramycin assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of tobramycin</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>tobramycin assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100046 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100046">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_28774"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_28774"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<obo:IAO_0000111>3,3',5'-triiodothyronine assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of 3,3',5'-triiodothyronine</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>3,3',5'-triiodothyronine assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100047 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100047">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000005897"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000005897"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100023"/>
<obo:IAO_0000111>C-reactive protein assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of C-reactive protein</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>C-reactive protein assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100048 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100048">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001977"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000556"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>megakaryocyte count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of megakaryocytes</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>megakaryocyte count assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100049 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100049">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001977"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000077"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>mesothelial cell count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of mesothelial cells</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>mesothelial cell count assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100050 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100050">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003027"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000235"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>macrophage count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of macrophages</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>macrophage count assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100051 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100051">
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000443"/>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_20067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_20067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:intersectionOf>
</owl:Class>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
<obo:IAO_0000111>3-hydroxybutyric acid assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of 3-hydroxybutyric acid</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>3-hydroxybutyric acid assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100052 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100052">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100001"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000014"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_2000014"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16526"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16526"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>panel5 venous blood carbon dioxide assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of carbon dioxide in venous blood as part of a panel5 order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>panel5 venous blood carbon dioxide assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100053 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100053">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100002"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000014"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_2000014"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_29101"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_29101"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>panel5 venous blood sodium assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of sodium in venous blood as part of a panel5 order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>panel5 venous blood sodium assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100054 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100054">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100003"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000014"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_2000014"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16737"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16737"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>panel5 venous blood creatinine assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of creatinine in venous blood as part of a panel5 order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>panel5 venous blood creatinine assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100055 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100055">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100004"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000014"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_2000014"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_29103"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_29103"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>panel5 venous blood potassium assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of potassium in venous blood as part of a panel5 order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>panel5 venous blood potassium assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100056 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100056">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003021"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000014"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_2000014"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
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<obo:IAO_0000111>automated differential venous blood basophil count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of basophils in venous blood as part of a automated differential order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>automated differential venous blood basophil count assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100057 -->
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<obo:IAO_0000111>automated differential venous blood neutrophil count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of neutrophils in venous blood as part of a automated differential order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>automated differential venous blood neutrophil count assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100058 -->
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<obo:IAO_0000111>automated differential venous blood eosinophil count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of eosinophils in venous blood as part of a automated differential order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>automated differential venous blood eosinophil count assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100059 -->
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<obo:IAO_0000111>automated differential venous blood lymphocyte count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of lymphocytes in venous blood as part of a automated differential order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>automated differential venous blood lymphocyte count assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100060 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100060">
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</owl:Restriction>
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<obo:IAO_0000111>automated differential venous blood monocyte count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of monocytes in venous blood as part of a automated differential order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>automated differential venous blood monocyte count assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100061 -->
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<obo:IAO_0000111>venous blood chloride assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of chloride in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood chloride assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100062 -->
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<obo:IAO_0000111>CBC with automated differential venous blood RBC count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of RBCs in venous blood as part of a CBC with automated differential order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>CBC with automated differential venous blood RBC count assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100063 -->
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<obo:IAO_0000111>CBC with automated differential venous blood platelet count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of platelets in venous blood as part of a CBC with automated differential order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>CBC with automated differential venous blood platelet count assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100064 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100064">
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000111>CBC with automated differential venous blood hemoglobin assay</obo:IAO_0000111>
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<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000111>venous blood phosphate assay</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of phosphate in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood phosphate assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100068 -->
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<obo:IAO_0000111>liver injury venous blood alanine aminotransferase assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of alanine aminotransferase in venous blood as part of a liver injury order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>liver injury venous blood alanine aminotransferase assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100069 -->
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<obo:IAO_0000111>liver injury venous blood human alkaline phosphatase assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
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<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100070 -->
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<obo:IAO_0000111>liver injury venous blood bilirubin assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
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<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100071 -->
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<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of human aspartate aminotransferase in venous blood as part of a liver injury order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000111>venous blood glucose assay</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of glucose in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood glucose assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100073 -->
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<obo:IAO_0000111>venous blood magnesium assay</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of magnesium in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood magnesium assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100074 -->
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<obo:IAO_0000111>CBC venous blood RBC count assay</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of RBCs in venous blood as part of a CBC order</obo:IAO_0000115>
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<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>CBC venous blood RBC count assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100075 -->
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<obo:IAO_0000111>CBC venous blood WBC count assay</obo:IAO_0000111>
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<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>CBC venous blood WBC count assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100076 -->
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<obo:IAO_0000111>CBC venous blood hematocrit assay</obo:IAO_0000111>
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<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>CBC venous blood hematocrit assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100077 -->
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<obo:IAO_0000111>CBC venous blood platelet count assay</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of platelets in venous blood as part of a CBC order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>CBC venous blood platelet count assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100078 -->
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<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100079 -->
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<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000111>liver evaluation venous blood globulin assay</obo:IAO_0000111>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100082 -->
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<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100083 -->
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<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
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<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100085 -->
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000111>liver evaluation venous blood protein assay</obo:IAO_0000111>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000111>basic metabolic panel venous blood chloride assay</obo:IAO_0000111>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100090 -->
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<obo:IAO_0000111>basic metabolic panel venous blood creatinine assay</obo:IAO_0000111>
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<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100091 -->
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<obo:IAO_0000111>basic metabolic panel venous blood glucose assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of glucose in venous blood as part of a basic metabolic panel order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100099 -->
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<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of band neutrophils in venous blood as part of a CBC with manual differential order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>CBC with manual differential venous blood band neutrophil count assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100100 -->
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<obo:IAO_0000111>CBC with manual differential venous blood WBC count assay</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of WBCs in venous blood as part of a CBC with manual differential order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>CBC with manual differential venous blood WBC count assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100101 -->
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<obo:IAO_0000111>CBC with manual differential venous blood eosinophil count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of eosinophils in venous blood as part of a CBC with manual differential order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>CBC with manual differential venous blood eosinophil count assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100102 -->
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<obo:IAO_0000111>CBC with manual differential venous blood lymphocyte count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of lymphocytes in venous blood as part of a CBC with manual differential order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>CBC with manual differential venous blood lymphocyte count assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100103 -->
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<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of nucleated RBCs in venous blood as part of a CBC with manual differential order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>CBC with manual differential venous blood nucleated RBC count assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100104 -->
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<obo:IAO_0000111>CBC with manual differential venous blood monocyte count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of monocytes in venous blood as part of a CBC with manual differential order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>CBC with manual differential venous blood monocyte count assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100105 -->
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<obo:IAO_0000111>CBC with manual differential venous blood segmented neutrophil count assay</obo:IAO_0000111>
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<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100106 -->
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</owl:Restriction>
</owl:someValuesFrom>
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<obo:IAO_0000111>CBC with manual differential venous blood basophil count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of basophils in venous blood as part of a CBC with manual differential order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>CBC with manual differential venous blood basophil count assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100107 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100107">
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000003918"/>
</owl:Restriction>
</owl:intersectionOf>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000003918"/>
</owl:Restriction>
</owl:intersectionOf>
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<obo:IAO_0000111>venous blood albumin assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of albumin in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood albumin assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100108 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100108">
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000014"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000029971"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
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</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000029971"/>
</owl:Restriction>
</owl:intersectionOf>
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<obo:IAO_0000111>cardiac enzymes venous blood creatine kinase assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of creatine kinase in venous blood as part of a cardiac enzymes order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>cardiac enzymes venous blood creatine kinase assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100109 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100109">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100023"/>
<rdfs:subClassOf>
<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000014"/>
</owl:Restriction>
</owl:intersectionOf>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000008725"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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</owl:Restriction>
</owl:intersectionOf>
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<obo:IAO_0000111>venous blood haptoglobin assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of haptoglobin in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood haptoglobin assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100110 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100110">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100028"/>
<rdfs:subClassOf>
<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000014"/>
</owl:Restriction>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000050331"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>venous blood lactate dehydrogenase assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures lactate dehydrogenase in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood lactate dehydrogenase assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100111 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100111">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100023"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000016801"/>
</owl:Restriction>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000016801"/>
</owl:Restriction>
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<obo:IAO_0000111>venous blood prealbunin assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of prealbunin in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood prealbunin assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100112 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100112">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100029"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17855"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17855"/>
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<obo:IAO_0000111>lipid panel venous blood triglyceride assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of triglyceride in venous blood as part of a lipid panel order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>lipid panel venous blood triglyceride assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100113 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100113">
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100030"/>
<rdfs:subClassOf>
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<!-- http://purl.obolibrary.org/obo/OBI_2100115 -->
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000115 xml:lang="en">An assay that measures hemoglobin A1c in venous blood</obo:IAO_0000115>
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<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100118 -->
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<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100119 -->
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100120 -->
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<owl:someValuesFrom>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000003015"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>venous blood prostate specific antigen assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of prostate specific antigen in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood prostate specific antigen assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100121 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100121">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003043"/>
<rdfs:subClassOf>
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<owl:intersectionOf rdf:parseType="Collection">
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000651"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
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</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
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<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000918"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>24 hour total urine volume assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures volume in urine as part of a 24 hour total order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>24 hour total urine volume assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100122 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100122">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100035"/>
<rdfs:subClassOf>
<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
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<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000014"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
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<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_30660"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_30660"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>T4 uptake venous blood T4 assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of T4 in venous blood as part of a T4 uptake order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>T4 uptake venous blood T4 assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100123 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100123">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100020"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000013"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17234"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17234"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>arterial blood glucose assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of glucose in arterial blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>arterial blood glucose assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100124 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100124">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001977"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf>
<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
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<owl:Class>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000014"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
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</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
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<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>CBC with manual differential venous blood cell count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of cells in venous blood as part of a CBC with manual differential order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>CBC with manual differential venous blood cell count assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100125 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100125">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100036"/>
<rdfs:subClassOf>
<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000013"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33262"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33262"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>hemoglobin oxygen saturation arterial blood oxygen assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of oxygen in arterial blood as part of a hemoglobin oxygen saturation order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>hemoglobin oxygen saturation arterial blood oxygen assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100126 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100126">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100014"/>
<rdfs:subClassOf>
<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000013"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
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</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
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<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
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<owl:intersectionOf rdf:parseType="Collection">
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35143"/>
</owl:Restriction>
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</owl:someValuesFrom>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35143"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>hemoglobin oxygen saturation arterial blood hemoglobin assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of hemoglobin in arterial blood as part of a hemoglobin oxygen saturation order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>hemoglobin oxygen saturation arterial blood hemoglobin assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100127 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100127">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100002"/>
<rdfs:subClassOf>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000014"/>
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</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100128 -->
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<obo:IAO_0000111>inpatient profile venous blood creatinine assay</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of creatinine in venous blood as part of a inpatient profile order</obo:IAO_0000115>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100129 -->
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100130 -->
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<obo:IAO_0000111>inpatient profile venous blood carbon dioxide assay</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of carbon dioxide in venous blood as part of a inpatient profile order</obo:IAO_0000115>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100131 -->
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<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of folic acid in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100132 -->
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<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>count venous blood reticulocyte count assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100133 -->
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100134 -->
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<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000111>venous blood transferrin assay</obo:IAO_0000111>
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<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100136 -->
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<obo:IAO_0000111>venous blood sodium assay</obo:IAO_0000111>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100137 -->
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100139 -->
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<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of creatinine in urine</obo:IAO_0000115>
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<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100140 -->
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<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100141 -->
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<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100142 -->
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<obo:IAO_0000111>cooximitery arterial blood hemoglobin assay</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of hemoglobin in arterial blood as part of a cooximitery order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>cooximitery arterial blood hemoglobin assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100143 -->
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<obo:IAO_0000111>cooximitery arterial blood methemoglobin assay</obo:IAO_0000111>
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<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>cooximitery arterial blood methemoglobin assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100144 -->
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<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of sodium in urine as part of a electrolytes order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>electrolytes urine sodium assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100145 -->
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<obo:IAO_0000111>electrolytes urine potassium assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of potassium in urine as part of a electrolytes order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>electrolytes urine potassium assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100146 -->
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<obo:IAO_0000111>Biosite cardiac panel arterial blood creatine kinase MB assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures creatine kinase MB in arterial blood as part of a Biosite cardiac panel order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>Biosite cardiac panel arterial blood creatine kinase MB assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100147 -->
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<obo:IAO_0000111>venous blood fibrinogen assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures fibrinogen in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood fibrinogen assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100148 -->
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100150 -->
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<!-- http://purl.obolibrary.org/obo/OBI_2100151 -->
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<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000111>venous blood LDH assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures LDH in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood LDH assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100162 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100162">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100041"/>
<rdfs:subClassOf>
<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000027247"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>venous blood creatine kinase MB assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures creatine kinase MB in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood creatine kinase MB assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100163 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100163">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100042"/>
<rdfs:subClassOf>
<owl:Class>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000014"/>
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</owl:Class>
</owl:someValuesFrom>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
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</owl:Restriction>
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<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_28358"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>venous blood lactic acid assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures lactic acid in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood lactic acid assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100164 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100164">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003018"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000014"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000232"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>venous blood hematocrit assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the proportion of red blood cells in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood hematocrit assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100165 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100165">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100003"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000014"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
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</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
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<owl:Class>
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<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16737"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16737"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>venous blood creatinine assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of creatinine in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood creatinine assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100166 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100166">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100036"/>
<rdfs:subClassOf>
<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
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</owl:someValuesFrom>
</owl:Restriction>
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<owl:someValuesFrom>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33262"/>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33262"/>
</owl:Restriction>
</owl:intersectionOf>
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</rdfs:subClassOf>
<obo:IAO_0000111>blood gas venous blood oxygen assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of oxygen in venous blood as part of a blood gas order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>blood gas venous blood oxygen assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100167 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100167">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100024"/>
<rdfs:subClassOf>
<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000014"/>
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</owl:someValuesFrom>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_39123"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_39123"/>
</owl:Restriction>
</owl:intersectionOf>
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</rdfs:subClassOf>
<obo:IAO_0000111>ionized venous blood ionized calcium assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of ionized calcium in venous blood as part of a ionized order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>ionized venous blood ionized calcium assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100168 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100168">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100001"/>
<rdfs:subClassOf>
<owl:Class>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000014"/>
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</owl:someValuesFrom>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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</owl:someValuesFrom>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16526"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16526"/>
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</rdfs:subClassOf>
<obo:IAO_0000111>blood gas venous blood carbon dioxide assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of carbon dioxide in venous blood as part of a blood gas order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100169 -->
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<obo:IAO_0000111>blood gas venous blood bicarbonate assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of bicarbonate in venous blood as part of a blood gas order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>blood gas venous blood bicarbonate assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100170 -->
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<obo:IAO_0000111>arterial blood creatinine assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of creatinine in arterial blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>arterial blood creatinine assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100171 -->
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<obo:IAO_0000111>venous blood tacrolimus assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of tacrolimus in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood tacrolimus assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100172 -->
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<obo:IAO_0000111>random venous blood vancomycin assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of vancomycin in venous blood as part of a random order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>random venous blood vancomycin assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100173 -->
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<obo:IAO_0000111>venous blood mycophenolic acid assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of mycophenolic acid in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood mycophenolic acid assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100174 -->
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<obo:IAO_0000111>non-vented blood gas arterial blood carbon dioxide assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of carbon dioxide in arterial blood as part of a non-vented blood gas order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>non-vented blood gas arterial blood carbon dioxide assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100175 -->
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</owl:Restriction>
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<obo:IAO_0000111>non-vented blood gas arterial blood oxygen assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of oxygen in arterial blood as part of a non-vented blood gas order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>non-vented blood gas arterial blood oxygen assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100176 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100176">
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100043"/>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17544"/>
</owl:Restriction>
</owl:intersectionOf>
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<owl:Restriction>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17544"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>non-vented blood gas arterial blood bicarbonate assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of bicarbonate in arterial blood as part of a non-vented blood gas order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>non-vented blood gas arterial blood bicarbonate assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100177 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100177">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf>
<owl:Class>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000014"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
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</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0071735"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>quantitative venous blood IgG assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures IgG in venous blood as part of a quantitative order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>quantitative venous blood IgG assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100178 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100178">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000014"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
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</owl:Restriction>
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</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0071753"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>quantitative venous blood IgM assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures IgM in venous blood as part of a quantitative order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>quantitative venous blood IgM assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100179 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100179">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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</owl:Restriction>
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</owl:Class>
</owl:someValuesFrom>
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</owl:Restriction>
</owl:intersectionOf>
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</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0071745"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>quantitative venous blood IgA assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures IgA in venous blood as part of a quantitative order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>quantitative venous blood IgA assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100180 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100180">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100002"/>
<rdfs:subClassOf>
<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000013"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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</owl:Restriction>
</owl:intersectionOf>
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</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
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<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_29101"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_29101"/>
</owl:Restriction>
</owl:intersectionOf>
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</rdfs:subClassOf>
<obo:IAO_0000111>arterial blood sodium assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of sodium in arterial blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>arterial blood sodium assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100181 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100181">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100004"/>
<rdfs:subClassOf>
<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000013"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
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<owl:Restriction>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
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</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
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<owl:someValuesFrom>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_29103"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_29103"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>arterial blood potassium assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of potassium in arterial blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>arterial blood potassium assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100182 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100182">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100024"/>
<rdfs:subClassOf>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000013"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_39123"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_39123"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>ionized arterial blood calcium assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of calcium in arterial blood as part of a ionized order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>ionized arterial blood calcium assay</rdfs:label>
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<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000111>venous blood 25-hydroxyvitamin D2 assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of 25-hydroxyvitamin D2 in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood 25-hydroxyvitamin D2 assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100204 -->
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<obo:IAO_0000111>venous blood digoxin assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of digoxin in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood digoxin assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100205 -->
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<obo:IAO_0000111>urine protein assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of protein in urine</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>urine protein assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100206 -->
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<obo:IAO_0000111>venous blood tobramycin assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of tobramycin in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood tobramycin assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100207 -->
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<obo:IAO_0000111>CBC with manual differential venous blood myelocyte count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of myelocytes in venous blood as part of a CBC with manual differential order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>CBC with manual differential venous blood myelocyte count assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100208 -->
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<obo:IAO_0000111>SPEP protein electrophoresis venous blood beta-globin assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of beta-globin in venous blood as part of a SPEP protein electrophoresis order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>SPEP protein electrophoresis venous blood beta-globin assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100209 -->
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<obo:IAO_0000111>SPEP protein electrophoresis venous blood albumin assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
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<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>SPEP protein electrophoresis venous blood albumin assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100210 -->
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<obo:IAO_0000111>hepatic panel venous blood human alkaline phosphatase assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of human alkaline phosphatase in venous blood as part of a hepatic panel order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>hepatic panel venous blood human alkaline phosphatase assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100218 -->
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0003094"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
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<obo:IAO_0000111>estimated venous blood glomerular filtration assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures glomerular filtration in venous blood as part of a estimated order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>estimated venous blood glomerular filtration assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100219 -->
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16737"/>
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</owl:Restriction>
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<obo:IAO_0000111>DT60 venous blood creatinine assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of creatinine in venous blood as part of a DT60 order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>DT60 venous blood creatinine assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100220 -->
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<obo:IAO_0000111>fasting venous blood glucose assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of glucose in venous blood as part of a fasting order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>fasting venous blood glucose assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100221 -->
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</owl:Restriction>
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<obo:IAO_0000111>random venous blood amikacin assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of amikacin in venous blood as part of a random order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>random venous blood amikacin assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100222 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100222">
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<obo:IAO_0000111>venous blood ammonia assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of ammonia in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood ammonia assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100223 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100223">
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100023"/>
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<obo:IAO_0000111>venous blood GGT assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of GGT in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood GGT assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100224 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100224">
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100015"/>
<rdfs:subClassOf>
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<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of phosphate in venous blood as part of a chem11 order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000111>chem11 venous blood potassium assay</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of potassium in venous blood as part of a chem11 order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>chem11 venous blood potassium assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100226 -->
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<obo:IAO_0000111>chem11 venous blood calcium assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of calcium in venous blood as part of a chem11 order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>chem11 venous blood calcium assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100227 -->
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<obo:IAO_0000111>chem11 venous blood glucose assay</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of glucose in venous blood as part of a chem11 order</obo:IAO_0000115>
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<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>chem11 venous blood glucose assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100228 -->
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<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of carbon dioxide in venous blood as part of a chem11 order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>chem11 venous blood carbon dioxide assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100229 -->
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<obo:IAO_0000111>chem11 venous blood albumin assay</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of albumin in venous blood as part of a chem11 order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100230 -->
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000115 xml:lang="en">An assay that measures IgE in venous blood as part of a total order</obo:IAO_0000115>
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<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of human aspartate aminotransferase in venous blood as part of a chem16 order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000111>chem16 venous blood magnesium assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of magnesium in venous blood as part of a chem16 order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>chem16 venous blood magnesium assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100238 -->
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<obo:IAO_0000111>chem16 venous blood carbon dioxide assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of carbon dioxide in venous blood as part of a chem16 order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>chem16 venous blood carbon dioxide assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100239 -->
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<obo:IAO_0000111>chem16 venous blood glucose assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of glucose in venous blood as part of a chem16 order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>chem16 venous blood glucose assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100240 -->
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<obo:IAO_0000111>chem16 venous blood calcium assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of calcium in venous blood as part of a chem16 order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>chem16 venous blood calcium assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100241 -->
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<obo:IAO_0000111>chem16 venous blood triglyceride assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of triglyceride in venous blood as part of a chem16 order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>chem16 venous blood triglyceride assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100242 -->
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<obo:IAO_0000111>chem16 venous blood sodium assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of sodium in venous blood as part of a chem16 order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>chem16 venous blood sodium assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100243 -->
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<obo:IAO_0000111>chem16 venous blood phosphate assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of phosphate in venous blood as part of a chem16 order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>chem16 venous blood phosphate assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100244 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100244">
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<obo:IAO_0000111>chem16 venous blood human alkaline phosphatase assay</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of human alkaline phosphatase in venous blood as part of a chem16 order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100245 -->
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<obo:IAO_0000111>chem16 venous blood albumin assay</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of albumin in venous blood as part of a chem16 order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100246 -->
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<obo:IAO_0000111>chem16 venous blood bilirubin assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of bilirubin in venous blood as part of a chem16 order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>chem16 venous blood bilirubin assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100247 -->
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<obo:IAO_0000111>chem16 venous blood chloride assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of chloride in venous blood as part of a chem16 order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>chem16 venous blood chloride assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100248 -->
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<obo:IAO_0000111>chem16 venous blood alanine aminotransferase assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of alanine aminotransferase in venous blood as part of a chem16 order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>chem16 venous blood alanine aminotransferase assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100249 -->
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<obo:IAO_0000111>chem16 venous blood potassium assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
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<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100250 -->
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<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of glucose in arterial blood as part of a POC chem8 order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>POC chem8 arterial blood glucose assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100251 -->
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<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100253 -->
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100254 -->
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100255 -->
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<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100256 -->
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<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100257 -->
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<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000111>24 hour urine creatinine assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of creatinine in urine as part of a 24 hour order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>24 hour urine creatinine assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100259 -->
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<obo:IAO_0000111>intact venous blood PTH assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of PTH in venous blood as part of a intact order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>intact venous blood PTH assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100260 -->
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<obo:IAO_0000111>total venous blood PSA assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of PSA in venous blood as part of a total order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>total venous blood PSA assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100261 -->
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<obo:IAO_0000111>total venous blood T3 assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of T3 in venous blood as part of a total order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>total venous blood T3 assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100262 -->
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<obo:IAO_0000111>24 hour urine protein assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of protein in urine as part of a 24 hour order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>24 hour urine protein assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100263 -->
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<obo:IAO_0000111>total venous blood cholesterol assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of cholesterol in venous blood as part of a total order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>total venous blood cholesterol assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100264 -->
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<obo:IAO_0000111>venous blood triglyceride assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of triglyceride in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood triglyceride assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100265 -->
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<obo:IAO_0000111>tube 4 count cerebrospinal fluid cell count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of cells in cerebrospinal fluid as part of a tube 4 count order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>tube 4 count cerebrospinal fluid cell count assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100266 -->
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<obo:IAO_0000111>cerebrospinal fluid protein assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of protein in cerebrospinal fluid</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>cerebrospinal fluid protein assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100267 -->
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<obo:IAO_0000111>cerebrospinal fluid glucose assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of glucose in cerebrospinal fluid</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>cerebrospinal fluid glucose assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100268 -->
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<obo:IAO_0000111>tube 1 count cerebrospinal fluid cell count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of cells in cerebrospinal fluid as part of a tube 1 count order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>tube 1 count cerebrospinal fluid cell count assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100269 -->
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<obo:IAO_0000111>venous blood dehydroepiandrosterone assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of dehydroepiandrosterone in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood dehydroepiandrosterone assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100270 -->
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<obo:IAO_0000111>venous blood cortisol assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of cortisol in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood cortisol assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100271 -->
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<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100272 -->
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<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100273 -->
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<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100274 -->
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<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100275 -->
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<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>ABL90 panel arterial blood hemoglobin assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100276 -->
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<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100277 -->
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<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100278 -->
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<obo:IAO_0000111>ABL90 panel arterial blood hematocrit assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the proportion of red blood cells in arterial blood as part of a ABL90 panel order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>ABL90 panel arterial blood hematocrit assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100279 -->
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<obo:IAO_0000111>ABL90 panel arterial blood calcium assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of calcium in arterial blood as part of a ABL90 panel order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>ABL90 panel arterial blood calcium assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100280 -->
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<obo:IAO_0000111>ABL90 panel arterial blood temperature assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures temperature in arterial blood as part of a ABL90 panel order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>ABL90 panel arterial blood temperature assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100281 -->
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<obo:IAO_0000111>ABL90 panel arterial blood bicarbonate assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of bicarbonate in arterial blood as part of a ABL90 panel order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>ABL90 panel arterial blood bicarbonate assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100282 -->
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<obo:IAO_0000111>ABL90 panel arterial blood potassium assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of potassium in arterial blood as part of a ABL90 panel order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>ABL90 panel arterial blood potassium assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100283 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100283">
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<obo:IAO_0000111>CBC with manual differential venous blood promyelocyte count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of promyelocytes in venous blood as part of a CBC with manual differential order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>CBC with manual differential venous blood promyelocyte count assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100284 -->
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<obo:IAO_0000111>ABL90 panel venous blood glucose assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of glucose in venous blood as part of a ABL90 panel order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>ABL90 panel venous blood glucose assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100285 -->
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<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>ABL90 panel venous blood hematocrit assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100289 -->
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<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100290 -->
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<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100291 -->
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100292 -->
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<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100295 -->
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100296 -->
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<obo:IAO_0000111>ABL90 panel venous blood potassium assay</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of potassium in venous blood as part of a ABL90 panel order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100297 -->
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<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of sodium in urine</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100298 -->
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<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100299 -->
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of nucleated RBCs in venous blood as part of a CBC with automated differential order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100310 -->
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<obo:IAO_0000111>high sensitivity cardiac/neonatal venous blood c-reactive protein assay</obo:IAO_0000111>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100311 -->
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100312 -->
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<obo:IAO_0000111>GEM4000 ANLCOOX arterial blood carbon dioxide assay</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of carbon dioxide in arterial blood as part of a GEM4000 ANLCOOX order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>GEM4000 ANLCOOX arterial blood carbon dioxide assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100321 -->
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<obo:IAO_0000111>GEM4000 ANLCOOX arterial blood sodium assay</obo:IAO_0000111>
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<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of sodium in arterial blood as part of a GEM4000 ANLCOOX order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
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<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>GEM4000 ANLCOOX arterial blood sodium assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100322 -->
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<obo:IAO_0000111>ionized venous blood calcium assay</obo:IAO_0000111>
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<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>ionized venous blood calcium assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100323 -->
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<obo:IAO_0000111>venous blood hemoglobin assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of hemoglobin in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood hemoglobin assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100324 -->
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<obo:IAO_0000111>CBC with manual differential venous blood megakaryocyte count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of megakaryocytes in venous blood as part of a CBC with manual differential order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>CBC with manual differential venous blood megakaryocyte count assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100325 -->
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<obo:IAO_0000111>non-cardiac venous blood c-reactive protein assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
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<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>non-cardiac venous blood c-reactive protein assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100326 -->
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<owl:someValuesFrom>
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<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000003015"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000003015"/>
</owl:Restriction>
</owl:intersectionOf>
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<obo:IAO_0000111>intraoperative venous blood PTH assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of PTH in venous blood as part of a intraoperative order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>intraoperative venous blood PTH assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100327 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100327">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100023"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000014"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_2000014"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
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<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000013429"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000013429"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>venous blood parathyroid hormone assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of parathyroid hormone in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood parathyroid hormone assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100328 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100328">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100023"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000009"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_2000009"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>total bodily fluid protein assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of protein in bodily fluid as part of a total order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>total bodily fluid protein assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100329 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100329">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100020"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000009"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_2000009"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17234"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17234"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>bodily fluid glucose assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of glucose in bodily fluid</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>bodily fluid glucose assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100330 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100330">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001977"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000009"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_2000009"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>count bodily fluid cell count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of cells in bodily fluid as part of a count order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>count bodily fluid cell count assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100331 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100331">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003022"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000009"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_2000009"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0011114"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>manual differential bodily fluid segmented neutrophil count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of segmented neutrophils in bodily fluid as part of a manual differential order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>manual differential bodily fluid segmented neutrophil count assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100332 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100332">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001977"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000009"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_2000009"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000077"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>manual differential bodily fluid mesothelial cell count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of mesothelial cells in bodily fluid as part of a manual differential order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>manual differential bodily fluid mesothelial cell count assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100333 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100333">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003025"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000009"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_2000009"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000576"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>manual differential bodily fluid monocyte count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of monocytes in bodily fluid as part of a manual differential order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>manual differential bodily fluid monocyte count assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100334 -->
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<obo:IAO_0000111>manual differential bodily fluid lymphocyte count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of lymphocytes in bodily fluid as part of a manual differential order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>manual differential bodily fluid lymphocyte count assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100335 -->
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<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of macrophages in bodily fluid as part of a manual differential order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>manual differential bodily fluid macrophage count assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100336 -->
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<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of basophils in bodily fluid as part of a manual differential order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>manual differential bodily fluid basophil count assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100337 -->
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<obo:IAO_0000111>manual differential bodily fluid eosinophil count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of eosinophils in bodily fluid as part of a manual differential order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>manual differential bodily fluid eosinophil count assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100338 -->
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<obo:IAO_0000111>liver function venous blood bilirubin assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of bilirubin in venous blood as part of a liver function order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>liver function venous blood bilirubin assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100339 -->
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<obo:IAO_0000111>liver function venous blood alanine aminotransferase assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of alanine aminotransferase in venous blood as part of a liver function order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>liver function venous blood alanine aminotransferase assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100340 -->
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<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of human aspartate aminotransferase in venous blood as part of a liver function order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>liver function venous blood human aspartate aminotransferase assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100341 -->
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<obo:IAO_0000111>liver function venous blood albumin assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
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<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
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<!-- http://purl.obolibrary.org/obo/OBI_2100342 -->
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<obo:IAO_0000111>liver function venous blood protein assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of protein in venous blood as part of a liver function order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>liver function venous blood protein assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100343 -->
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<obo:IAO_0000111>liver function venous blood human alkaline phosphatase assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of human alkaline phosphatase in venous blood as part of a liver function order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>liver function venous blood human alkaline phosphatase assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100344 -->
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<obo:IAO_0000111>vitamin B12 and Folate venous blood folic acid assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of folic acid in venous blood as part of a vitamin B12 and Folate order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>vitamin B12 and Folate venous blood folic acid assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100345 -->
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</owl:Restriction>
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<obo:IAO_0000111>bodily fluid cell count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of cells in bodily fluid</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>bodily fluid cell count assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100346 -->
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<obo:IAO_0000111>venous blood reticulocyte count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of reticulocytes in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood reticulocyte count assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100347 -->
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<obo:IAO_0000111>bodily fluid cholesterol assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of cholesterol in bodily fluid</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>bodily fluid cholesterol assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100348 -->
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_81567"/>
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</owl:Class>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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</owl:Restriction>
</owl:intersectionOf>
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<obo:IAO_0000111>TSH reflex Free T4 venous blood thyroid stimulating hormone assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of thyroid stimulating hormone in venous blood as part of a TSH reflex Free T4 order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>TSH reflex Free T4 venous blood thyroid stimulating hormone assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100349 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100349">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000014"/>
</owl:Restriction>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
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</owl:Restriction>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16990"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16990"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>direct venous blood bilirubin assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of bilirubin in venous blood as part of a direct order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>direct venous blood bilirubin assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100350 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100350">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100046"/>
<rdfs:subClassOf>
<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000014"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_28774"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_28774"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>free venous blood T3 assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of T3 in venous blood as part of a free order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>free venous blood T3 assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100351 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100351">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100022"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000009"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000003918"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000003918"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>bodily fluid albumin assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of albumin in bodily fluid</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>bodily fluid albumin assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100352 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100352">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100029"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000009"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17855"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17855"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>bodily fluid triglyceride assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of triglyceride in bodily fluid</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>bodily fluid triglyceride assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100353 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100353">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003018"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf>
<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
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<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000014"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000232"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>hemoglobin and hematocrit venous blood hematocrit assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the proportion of red blood cells in venous blood as part of a hemoglobin and hematocrit order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>hemoglobin and hematocrit venous blood hematocrit assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100354 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100354">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100014"/>
<rdfs:subClassOf>
<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000014"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
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</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35143"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35143"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>hemoglobin and hematocrit venous blood hemoglobin assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of hemoglobin in venous blood as part of a hemoglobin and hematocrit order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>hemoglobin and hematocrit venous blood hemoglobin assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100355 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100355">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100024"/>
<rdfs:subClassOf>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000014"/>
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</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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</owl:Restriction>
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</owl:Restriction>
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<owl:Restriction>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_39123"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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</owl:Restriction>
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<obo:IAO_0000111>venous blood ionized calcium assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of ionized calcium in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood ionized calcium assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100356 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100356">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000146"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>venous blood temperature assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures temperature in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood temperature assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100357 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100357">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100043"/>
<rdfs:subClassOf>
<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000014"/>
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</owl:Restriction>
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</owl:someValuesFrom>
</owl:Restriction>
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<owl:someValuesFrom>
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<owl:intersectionOf rdf:parseType="Collection">
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17544"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
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</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17544"/>
</owl:Restriction>
</owl:intersectionOf>
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</rdfs:subClassOf>
<obo:IAO_0000111>venous blood bicarbonate assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of bicarbonate in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood bicarbonate assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100358 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100358">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100036"/>
<rdfs:subClassOf>
<owl:Class>
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</owl:Restriction>
</owl:intersectionOf>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
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</owl:someValuesFrom>
</owl:Restriction>
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<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33262"/>
</owl:Restriction>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33262"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>venous blood oxygen assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of oxygen in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood oxygen assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100359 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100359">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100039"/>
<rdfs:subClassOf>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000014"/>
</owl:Restriction>
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</owl:Class>
</owl:someValuesFrom>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0002027"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>venous blood osmolality assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures osmolality in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood osmolality assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100360 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100360">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003028"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf>
<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
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</owl:Restriction>
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</owl:Class>
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</owl:someValuesFrom>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000233"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>liver fibrosis (chronic viral hepatitis) venous blood platelet count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of platelets in venous blood as part of a liver fibrosis (chronic viral hepatitis) order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>liver fibrosis (chronic viral hepatitis) venous blood platelet count assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100361 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100361">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100046"/>
<rdfs:subClassOf>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
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</owl:Restriction>
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</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_28774"/>
</owl:Restriction>
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</owl:someValuesFrom>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_28774"/>
</owl:Restriction>
</owl:intersectionOf>
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</rdfs:subClassOf>
<obo:IAO_0000111>venous blood T3 assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of T3 in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood T3 assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100362 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100362">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003022"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
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<owl:Restriction>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000775"/>
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<obo:IAO_0000111>CBC with manual differential venous blood neutrophil count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of neutrophils in venous blood as part of a CBC with manual differential order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>CBC with manual differential venous blood neutrophil count assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100363 -->
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16737"/>
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</owl:Restriction>
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<obo:IAO_0000111>creatinine clearance urine creatinine assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of creatinine in urine as part of a creatinine clearance order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>creatinine clearance urine creatinine assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100364 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100364">
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100051"/>
<rdfs:subClassOf>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_20067"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_20067"/>
</owl:Restriction>
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<obo:IAO_0000111>venous blood beta hydroxybutryic acid assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of beta hydroxybutryic acid in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood beta hydroxybutryic acid assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100365 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100365">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001977"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000556"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
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<obo:IAO_0000111>venous blood megakaryocyte count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of megakaryocytes in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood megakaryocyte count assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100366 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100366">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003018"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000562"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>venous blood nucleated RBC count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of nucleated RBCs in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood nucleated RBC count assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100367 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100367">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001977"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
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<owl:Restriction>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000738"/>
</owl:Restriction>
</owl:someValuesFrom>
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</rdfs:subClassOf>
<obo:IAO_0000111>venous blood WBC count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of WBCs in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood WBC count assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100368 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100368">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003026"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000558"/>
</owl:Restriction>
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<obo:IAO_0000111>automated count venous blood reticulocyte count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of reticulocytes in venous blood as part of a automated count order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>automated count venous blood reticulocyte count assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100369 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100369">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000443"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17230"/>
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<obo:IAO_0000111>total venous blood homocysteine assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of homocysteine in venous blood as part of a total order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>total venous blood homocysteine assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100370 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100370">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100023"/>
<rdfs:subClassOf>
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<obo:IAO_0000111>venous blood Ceruloplasmin assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of Ceruloplasmin in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood Ceruloplasmin assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100371 -->
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<owl:Restriction>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17544"/>
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</owl:Class>
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</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
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<obo:IAO_0000111>GEM4 arterial blood bicarbonate assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of bicarbonate in arterial blood as part of a GEM4 order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>GEM4 arterial blood bicarbonate assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100372 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100372">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100042"/>
<rdfs:subClassOf>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_28358"/>
</owl:Restriction>
</owl:someValuesFrom>
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<obo:IAO_0000111>GEM4 arterial blood lactic acid assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures lactic acid in arterial blood as part of a GEM4 order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>GEM4 arterial blood lactic acid assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100373 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100373">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100014"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000013"/>
</owl:Restriction>
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</owl:Class>
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<obo:IAO_0000111>GEM4 arterial blood hemoglobin assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of hemoglobin in arterial blood as part of a GEM4 order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>GEM4 arterial blood hemoglobin assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100374 -->
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<owl:Restriction>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_29101"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_29101"/>
</owl:Restriction>
</owl:intersectionOf>
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<obo:IAO_0000111>GEM4 arterial blood sodium assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of sodium in arterial blood as part of a GEM4 order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>GEM4 arterial blood sodium assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100375 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100375">
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100004"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_29103"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_29103"/>
</owl:Restriction>
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</rdfs:subClassOf>
<obo:IAO_0000111>GEM4 arterial blood potassium assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of potassium in arterial blood as part of a GEM4 order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>GEM4 arterial blood potassium assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100376 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100376">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
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</owl:Restriction>
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</owl:someValuesFrom>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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</owl:someValuesFrom>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000146"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
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<obo:IAO_0000111>GEM4 arterial blood temperature assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures temperature in arterial blood as part of a GEM4 order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>GEM4 arterial blood temperature assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100377 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100377">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100020"/>
<rdfs:subClassOf>
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<obo:IAO_0000111>GEM4 arterial blood glucose assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of glucose in arterial blood as part of a GEM4 order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>GEM4 arterial blood glucose assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100378 -->
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</owl:Restriction>
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<obo:IAO_0000111>GEM4 arterial blood oxygen assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of oxygen in arterial blood as part of a GEM4 order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>GEM4 arterial blood oxygen assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100379 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100379">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003018"/>
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</owl:Restriction>
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<obo:IAO_0000111>GEM4 arterial blood hematocrit assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the proportion of red blood cells in arterial blood as part of a GEM4 order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>GEM4 arterial blood hematocrit assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100380 -->
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100024"/>
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<obo:IAO_0000111>GEM4 arterial blood ionized calcium assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of ionized calcium in arterial blood as part of a GEM4 order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>GEM4 arterial blood ionized calcium assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100381 -->
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<obo:IAO_0000111>GEM4 arterial blood carbon dioxide assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of carbon dioxide in arterial blood as part of a GEM4 order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>GEM4 arterial blood carbon dioxide assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100382 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100382">
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000233"/>
</owl:Restriction>
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<obo:IAO_0000111>liver fibrosis (NAFLD) venous blood platelet count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of platelets in venous blood as part of a liver fibrosis (NAFLD) order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>liver fibrosis (NAFLD) venous blood platelet count assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100383 -->
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<obo:IAO_0000111>venous blood beta hydroxybutric acid assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of beta hydroxybutric acid in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood beta hydroxybutric acid assay</rdfs:label>
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<!-- http://purl.obolibrary.org/obo/OBI_2100384 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100384">
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000786"/>
</owl:Restriction>
</owl:someValuesFrom>
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<obo:IAO_0000111>CBC with manual differential venous blood plasma cell count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of plasma cells in venous blood as part of a CBC with manual differential order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>CBC with manual differential venous blood plasma cell count assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100385 -->
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000014"/>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000007141"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000007141"/>
</owl:Restriction>
</owl:intersectionOf>
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<obo:IAO_0000111>venous blood erythropoietin assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of erythropoietin in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood erythropoietin assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100386 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100386">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100036"/>
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<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000013"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33262"/>
</owl:Restriction>
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</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33262"/>
</owl:Restriction>
</owl:intersectionOf>
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<obo:IAO_0000111>blood gas arterial blood oxygen assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of oxygen in arterial blood as part of a blood gas order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>blood gas arterial blood oxygen assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100387 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100387">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100043"/>
<rdfs:subClassOf>
<owl:Class>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000013"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
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</owl:someValuesFrom>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17544"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17544"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>blood gas arterial blood bicarbonate assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of bicarbonate in arterial blood as part of a blood gas order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>blood gas arterial blood bicarbonate assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100388 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100388">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100001"/>
<rdfs:subClassOf>
<owl:Class>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000013"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
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<owl:Restriction>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
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</owl:someValuesFrom>
</owl:Restriction>
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<owl:someValuesFrom>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16526"/>
</owl:Restriction>
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</owl:Class>
</owl:someValuesFrom>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16526"/>
</owl:Restriction>
</owl:intersectionOf>
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</rdfs:subClassOf>
<obo:IAO_0000111>blood gas arterial blood carbon dioxide assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of carbon dioxide in arterial blood as part of a blood gas order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>blood gas arterial blood carbon dioxide assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100389 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100389">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100034"/>
<rdfs:subClassOf>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000014"/>
</owl:Restriction>
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</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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</owl:someValuesFrom>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000003015"/>
</owl:Restriction>
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</owl:someValuesFrom>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000003015"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>free/total venous blood PSA assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of PSA in venous blood as part of a free/total order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>free/total venous blood PSA assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100390 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100390">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003024"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003232"/>
<rdfs:subClassOf>
<owl:Class>
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<owl:Restriction>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002502"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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</owl:someValuesFrom>
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<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000542"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>cerebrospinal fluid lymphocyte count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of lymphocytes in cerebrospinal fluid</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>cerebrospinal fluid lymphocyte count assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100391 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100391">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003022"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003232"/>
<rdfs:subClassOf>
<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002502"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002502"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0011114"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>cerebrospinal fluid segmented neutrophil count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of segmented neutrophils in cerebrospinal fluid</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>cerebrospinal fluid segmented neutrophil count assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100392 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100392">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001977"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003232"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002502"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002502"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000077"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>cerebrospinal fluid mesothelial cell count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of mesothelial cells in cerebrospinal fluid</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>cerebrospinal fluid mesothelial cell count assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100393 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100393">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003027"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003232"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002502"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002502"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000235"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>cerebrospinal fluid macrophage count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of macrophages in cerebrospinal fluid</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>cerebrospinal fluid macrophage count assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100394 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100394">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003021"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003232"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002502"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002502"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000767"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>cerebrospinal fluid basophil count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of basophils in cerebrospinal fluid</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>cerebrospinal fluid basophil count assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100395 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100395">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003025"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003232"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002502"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002502"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000576"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>cerebrospinal fluid monocyte count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of monocytes in cerebrospinal fluid</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>cerebrospinal fluid monocyte count assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100396 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100396">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003023"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003232"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0002502"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002502"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000771"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>cerebrospinal fluid eosinophil count assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cytometry assay that measures the count of eosinophils in cerebrospinal fluid</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>cerebrospinal fluid eosinophil count assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100397 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100397">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100023"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000014"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_2000014"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000004580"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000004580"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<obo:IAO_0000111>venous blood beta-2-microglobulin assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of beta-2-microglobulin in venous blood</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>venous blood beta-2-microglobulin assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100398 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100398">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100032"/>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000067"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_2000014"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_2000014"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000275"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_47774"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_47774"/>
</owl:Restriction>
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<obo:IAO_0000111>lipid panel reflex direct venous blood low density lipoprotein assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of low density lipoprotein in venous blood as part of a Lipid panel reflex direct order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>lipid panel reflex direct venous blood low density lipoprotein assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100399 -->
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<owl:Restriction>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17855"/>
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</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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</owl:Restriction>
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</rdfs:subClassOf>
<obo:IAO_0000111>lipid panel reflex direct venous blood triglyceride assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of triglyceride in venous blood as part of a Lipid panel reflex direct order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>lipid panel reflex direct venous blood triglyceride assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100400 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100400">
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<rdfs:subClassOf>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
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</owl:intersectionOf>
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</owl:someValuesFrom>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:subClassOf>
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<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
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<owl:intersectionOf rdf:parseType="Collection">
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16113"/>
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</owl:Class>
</owl:someValuesFrom>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
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</owl:intersectionOf>
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</rdfs:subClassOf>
<obo:IAO_0000111>lipid panel reflex direct venous blood cholesterol assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of cholesterol in venous blood as part of a Lipid panel reflex direct order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>lipid panel reflex direct venous blood cholesterol assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100401 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_2100401">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003040"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_2100030"/>
<rdfs:subClassOf>
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<obo:IAO_0000111>lipid panel reflex direct venous blood high density lipoprotein assay</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An analyte assay that measures the abundance of high density lipoprotein in venous blood as part of a Lipid panel reflex direct order</obo:IAO_0000115>
<obo:IAO_0000117>Mark A. Miller, ORCID:0000-0001-9076-6066 & Chris Stoeckert, ORCID ORCID:0000-0002-5714-991X</obo:IAO_0000117>
<obo:IAO_0000119>PennTURBO team</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1253</obo:IAO_0000233>
<rdfs:label>lipid panel reflex direct venous blood high density lipoprotein assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_2100402 -->
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<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0400103"/>
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</owl:Restriction>
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</owl:intersectionOf>
</owl:Class>
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</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>pooled clone sequencing assay</obo:IAO_0000111>
<obo:IAO_0000112>Although a similar pooled clone sequencing method has recently been described by others for metagenome-derived medium-insert plasmids and large-insert fosmids, to our knowledge, we are the first to report the pooled strategy for sequencing of large-insert metagenomic clones while also critically evaluating the performance of this pooled strategy by comparing the results to barcoded reference sequences of the same clones.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A DNA sequencing assay in which the DNA input is derived from pooled clones (for example BACs and Fosmids) is sequenced.</obo:IAO_0000115>
<obo:IAO_0000117>Dan Berrios, ORCID: 0000-0003-4312-9552</obo:IAO_0000117>
<obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049660/</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1106</obo:IAO_0000233>
<obo:IAO_0000234>Bonita Lam</obo:IAO_0000234>
<rdfs:label>pooled clone sequencing assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_9999994 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_9999994">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000903"/>
<rdfs:subClassOf>
<owl:Class>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0002743"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_50076"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
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<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_50076"/>
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<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
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<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000201"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0003368"/>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>chromium release assay</obo:IAO_0000111>
<obo:IAO_0000112>Autologous EBV-transformed B-LCL were used as target cells for the influenza virus-specific CTL assays. Equal volumes of target and effector cells were added to triplicate wells of 96-well tissue culture plates, and 1:2 serial dilutions of effectors were made, producing effector-to-target (E:T) ratios of 100:1, 50:1, 25:1, and 12.5:1. After a 4-h incubation of the effector cells with the target cells, supernatants were collected following brief centrifugation and transferred to polystyrene tubes to be counted with the LKB 1272 Clinigamma counter (Wallac). Percent specific killing was determined with the following equation: (experimental 51Cr release - spontaneous 51Cr release)/(maximum 51Cr release - spontaneous 51Cr release) x 100.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An in vitro cell killing assay in which radioactive chromium is absorbed by cells and released into supernatant when the cells die. The amount of radioactivity measured in the supernatant is a proxy for the number of cells that have died.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000117>PlanAndPlannedProcess Branch</obo:IAO_0000117>
<rdfs:label>chromium release assay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OGMS_0000015 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000015">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
<obo:IAO_0000111>clinical history</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A series of statements representing health-relevant qualities of a patient and of a patient's family.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ogms.owl"/>
<rdfs:label>clinical history</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OGMS_0000023 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000023">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000019"/>
<obo:IAO_0000111>phenotype</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A (combination of) quality(ies) of an organism determined by the interaction of its genetic make-up and environment that differentiates specific instances of a species from other instances of the same species.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ogms.owl"/>
<rdfs:label>phenotype</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OGMS_0000031 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000031">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000016"/>
<obo:IAO_0000111>disease</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ogms.owl"/>
<rdfs:label>disease</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OGMS_0000063 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000063">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000031"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>disease course</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">The totality of all processes through which a given disease instance is realized.</obo:IAO_0000115>
<obo:IAO_0000232>replace 'OBI:occurrence of disease', need to add logical definition
The axioms of OBI occurence of disease:
Equivalent classes:
realizes some disease
Superclasses:
'has part' some 'pathologic process'
'has participant' some
(organism
and ('has role' some 'host of immune response role'))
biological_process
realizes some 'host of immune response role'</obo:IAO_0000232>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ogms.owl"/>
<rdfs:label>disease course</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OGMS_0000073 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000073">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
<obo:IAO_0000111>diagnosis</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">The representation of a conclusion of a diagnostic process.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ogms.owl"/>
<rdfs:label>diagnosis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OGMS_0000090 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000090">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
<obo:IAO_0000111>treatment</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A planned process whose completion is hypothesized by a health care provider to eliminate, prevent, or alleviate a disorder, the signs and symptoms of a disorder, or a pathological process</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ogms.owl"/>
<rdfs:label>treatment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OGMS_0000123 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000123">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
<obo:IAO_0000111 xml:lang="en">clinical data item</obo:IAO_0000111>
<obo:IAO_0000115>A data item that is about a patient and is the specified output of a health care process assay or diagnostic process</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ogms.owl"/>
<rdfs:label xml:lang="en">clinical data item</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OMIABIS_0000050 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OMIABIS_0000050">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000953"/>
<obo:IAO_0000111 xml:lang="en">fixed tissue specimen</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A processed specimen that is the output of a fixation process.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/omiabis.owl"/>
<rdfs:label xml:lang="en">fixed tissue specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OMIABIS_0000052 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OMIABIS_0000052">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OMIABIS_0000050"/>
<obo:IAO_0000111 xml:lang="en">fixed tissue slide specimen</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A fixed tissue specimen that is placed in a slide.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/omiabis.owl"/>
<rdfs:label xml:lang="en">fixed tissue slide specimen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OMRSE_00000012 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OMRSE_00000012">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<obo:IAO_0000111 xml:lang="en">health care provider role</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A human health care role inhering in an organization or human being that is realized by a process of providing health care services to an organism.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/omrse.owl"/>
<rdfs:label xml:lang="en">health care provider role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OMRSE_00000054 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OMRSE_00000054">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<obo:IAO_0000111 xml:lang="en">hospital role</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A healthcare provider role that inheres in an organization and is realized by providing inpatient care.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/omrse.owl"/>
<rdfs:label xml:lang="en">hospital role</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OMRSE_00000056 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OMRSE_00000056">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000245"/>
<obo:IAO_0000111 xml:lang="en">hospital organization</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">An organization that is the bearer of a hospital role.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/omrse.owl"/>
<rdfs:label xml:lang="en">hospital organization</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OPL_0000232 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000232">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
<obo:IAO_0000111>parasite organism</obo:IAO_0000111>
<obo:IAO_0000115>An organism living in, with, or on another organism in parasitism. Individual members of parasite species, such as Leishmania, Plasmodium, Trypanosoma, etc. are members of this class.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
<rdfs:label>parasite organism</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OPL_0000267 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000267">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
<obo:IAO_0000111>Plasmodium gametocyte</obo:IAO_0000111>
<obo:IAO_0000115>A Plasmodium that is located either in the bloodstream of the vertebrate host or midgut of mosquito vector during gametocyte stage. Gametocytes are the precursor cells of the macro- or microgametes</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
<rdfs:label>Plasmodium gametocyte</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0000001 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000001">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000020"/>
<obo:IAO_0000111>quality</obo:IAO_0000111>
<obo:IAO_0000115>A dependent entity that inheres in a bearer by virtue of how the bearer is related to other entities</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>quality</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0000011 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000011">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0000165"/>
<obo:IAO_0000111>age</obo:IAO_0000111>
<obo:IAO_0000115>A time quality inhering in a bearer by virtue of how long the bearer has existed.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>age</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0000018 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000018">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001296"/>
<obo:IAO_0000111>fluorescence</obo:IAO_0000111>
<obo:IAO_0000115>A luminous flux quality inhering in a bearer by virtue of the bearer's emitting longer wavelength light following the absorption of shorter wavelength radiation; fluorescence is common with aromatic compounds with several rings joined together.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>fluorescence</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0000025 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000025">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0000141"/>
<obo:IAO_0000111>composition</obo:IAO_0000111>
<obo:IAO_0000115>A single physical entity inhering in an bearer by virtue of the bearer's quantities or relative ratios of subparts.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>composition</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0000033 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000033">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0000070"/>
<obo:IAO_0000111>concentration of</obo:IAO_0000111>
<obo:IAO_0000115>A quality inhering in a substance by virtue of the amount of the bearer's there is mixed with another substance.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>concentration of</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0000047 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000047">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001995"/>
<obo:IAO_0000111>biological sex</obo:IAO_0000111>
<obo:IAO_0000115>An organismal quality inhering in a bearer by virtue of the bearer's ability to undergo sexual reproduction in order to differentiate the individuals or types involved.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>biological sex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0000051 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000051">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001241"/>
<obo:IAO_0000111>morphology</obo:IAO_0000111>
<obo:IAO_0000115>A quality of a single physical entity inhering in the bearer by virtue of the bearer's size or shape or structure.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>morphology</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0000070 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000070">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0103000"/>
<obo:IAO_0000111>amount</obo:IAO_0000111>
<obo:IAO_0000115>The number of entities of this type that are part of the whole organism.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>amount</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0000117 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000117">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0000051"/>
<obo:IAO_0000111>size</obo:IAO_0000111>
<obo:IAO_0000115>A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>size</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0000122 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000122">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001708"/>
<obo:IAO_0000111>length</obo:IAO_0000111>
<obo:IAO_0000115>A 1-D extent quality which is equal to the distance between two points.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>length</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0000125 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000125">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001018"/>
<obo:IAO_0000111>mass</obo:IAO_0000111>
<obo:IAO_0000115>A physical quality that inheres in a bearer by virtue of the proportion of the bearer's amount of matter.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>mass</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0000140 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000140">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001018"/>
<obo:IAO_0000111>position</obo:IAO_0000111>
<obo:IAO_0000115>A spatial quality inhering in a bearer by virtue of the bearer's spatial location relative to other objects in the vicinity.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>position</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0000141 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000141">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0000051"/>
<obo:IAO_0000111>structure</obo:IAO_0000111>
<obo:IAO_0000115>A morphology quality inhering in a bearer by virtue of the bearer's relative position, shape, arrangements and connectivity of an organism's various parts; the pattern underlying its form.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>structure</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0000146 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000146">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001018"/>
<obo:IAO_0000111>temperature</obo:IAO_0000111>
<obo:IAO_0000115>A physical quality of the thermal energy of a system.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>temperature</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0000165 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000165">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001018"/>
<obo:IAO_0000111>time</obo:IAO_0000111>
<obo:IAO_0000115>A quality in which events occur in sequence.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>time</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0000169 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000169">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001995"/>
<obo:IAO_0000111>viability</obo:IAO_0000111>
<obo:IAO_0000115>An organismal quality inhering in a bearer or a population by virtue of the bearer's disposition to survive and develop normally or the number of surviving individuals in a given population.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>viability</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0000186 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000186">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001995"/>
<obo:IAO_0000111>behavioral quality</obo:IAO_0000111>
<obo:IAO_0000115>An organismal quality inhering in a bearer by virtue of the bearer's behavior aggregate of the responses or reactions or movements in a given situation.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>behavioral quality</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0000383 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000383">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001894"/>
<obo:IAO_0000111>female</obo:IAO_0000111>
<obo:IAO_0000115>A biological sex quality inhering in an individual or a population that only produces gametes that can be fertilised by male gametes.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>female</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0000384 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000384">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001894"/>
<obo:IAO_0000111>male</obo:IAO_0000111>
<obo:IAO_0000115>A biological sex quality inhering in an individual or a population whose sex organs contain only male gametes.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>male</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0000918 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000918">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001710"/>
<obo:IAO_0000111>volume</obo:IAO_0000111>
<obo:IAO_0000115>A 3-D extent quality inhering in a bearer by virtue of the bearer's amount of 3-dimensional space it occupies.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>volume</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001018 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001018">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001241"/>
<obo:IAO_0000111>physical quality</obo:IAO_0000111>
<obo:IAO_0000115>A quality of a physical entity that exists through action of continuants at the physical level of organisation in relation to other entities.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>physical quality</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001020 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001020">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0000141"/>
<obo:IAO_0000111>damage</obo:IAO_0000111>
<obo:IAO_0000115>A structural quality inhering in a bearer by virtue of whether the bearer has been harmed or injured or spoiled.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>damage</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001025 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001025">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001018"/>
<obo:IAO_0000111>pressure</obo:IAO_0000111>
<obo:IAO_0000115>A physical quality that inheres in a bearer by virtue of the bearer's amount of force per unit area it exerts.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>pressure</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001161 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001161">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0000033"/>
<obo:IAO_0000111>diluted</obo:IAO_0000111>
<obo:IAO_0000115>A concentration which relatively low.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>diluted</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001167 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001167">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001020"/>
<obo:IAO_0000111>damaged</obo:IAO_0000111>
<obo:IAO_0000115>A structural quality inhering in a bearer by virtue of the bearer being harmed or injured or spoiled, such that its functionality is impaired.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>damaged</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001193 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001193">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0000140"/>
<obo:IAO_0000111>lateral to</obo:IAO_0000111>
<obo:IAO_0000115>A spatial quality inhering in a bearer by virtue of the bearer's being located toward the side relative to another entity.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>lateral to</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001196 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001196">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0000140"/>
<obo:IAO_0000111>ventral to</obo:IAO_0000111>
<obo:IAO_0000115>A spatial quality inhering in a bearer by virtue of the bearer's being located toward the abdomen of an organism relative to another entity.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>ventral to</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001233 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001233">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0000140"/>
<obo:IAO_0000111>dorsal to</obo:IAO_0000111>
<obo:IAO_0000115>A spatial quality inhering in a bearer by virtue of the bearer's being located toward the back or upper surface of an organism relative to another entity.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>dorsal to</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001241 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001241">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000019"/>
<obo:IAO_0000111>physical object quality</obo:IAO_0000111>
<obo:IAO_0000115>A quality which inheres in a continuant.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>physical object quality</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001296 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001296">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001300"/>
<obo:IAO_0000111>luminous flux</obo:IAO_0000111>
<obo:IAO_0000115>A scalar optical quality which obtains by the magnitude of the light emitted by the bearer.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>luminous flux</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001300 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001300">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0070060"/>
<obo:IAO_0000111>optical quality</obo:IAO_0000111>
<obo:IAO_0000115>An EM radiation quality in which the EM radiation is within the fiat range of the spectrum visible deemed to be light.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>optical quality</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001335 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001335">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001895"/>
<obo:IAO_0000111>bacterial mating type</obo:IAO_0000111>
<obo:IAO_0000115>A mating type that indicates whether the F plasmid has integrated into the chromosome.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>bacterial mating type</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001337 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001337">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001895"/>
<obo:IAO_0000111>yeast mating type</obo:IAO_0000111>
<obo:IAO_0000115>A yeast mating type.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>yeast mating type</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001338 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001338">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0002003"/>
<obo:IAO_0000111>mixed sex</obo:IAO_0000111>
<obo:IAO_0000115>A biological sex quality inhering in a population of multiple sexes.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>mixed sex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001339 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001339">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0000025"/>
<obo:IAO_0000111>biomaterial purity</obo:IAO_0000111>
<obo:IAO_0000115>A composition quality inhering in an bearer by virtue of the bearer's homogeneity of a biomaterial.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>biomaterial purity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001340 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001340">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001894"/>
<obo:IAO_0000111>hermaphrodite</obo:IAO_0000111>
<obo:IAO_0000115>A biological sex quality inhering in an organism or a population with both male and female sexual organs in one individual.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>hermaphrodite</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001341 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001341">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001342"/>
<obo:IAO_0000111>a mating type (yeast)</obo:IAO_0000111>
<obo:IAO_0000115>A S. cerevisiae mating type cells that secrete a pheromone that in alpha haploids stimulates processes that lead to mating.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>a mating type (yeast)</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001342 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001342">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001337"/>
<obo:IAO_0000111>Saccharomyces cerevisiae mating type</obo:IAO_0000111>
<obo:IAO_0000115>A S. cerevisiae mating type.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>Saccharomyces cerevisiae mating type</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001343 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001343">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001337"/>
<obo:IAO_0000111>Schizosaccharomyces pombe mating type</obo:IAO_0000111>
<obo:IAO_0000115>A S. pombe mating type determined by the gene configuration on the mat1 locus.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>Schizosaccharomyces pombe mating type</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001344 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001344">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001342"/>
<obo:IAO_0000111>alpha mating type (yeast)</obo:IAO_0000111>
<obo:IAO_0000115>A S. cerevisiae mating type cells that secrete a pheromone that stimulates a haploids.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>alpha mating type (yeast)</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001345 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001345">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001343"/>
<obo:IAO_0000111>h minus</obo:IAO_0000111>
<obo:IAO_0000115>A S. pombe mating type determined by the mat1-Mc and mat1-Mi on the mat1 locus.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>h minus</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001346 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001346">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001343"/>
<obo:IAO_0000111>h plus</obo:IAO_0000111>
<obo:IAO_0000115>A S. pombe mating type determined by the mat1-Pc and mat1-Pi on the mat1 locus.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>h plus</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001347 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001347">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001335"/>
<obo:IAO_0000111>F mating type</obo:IAO_0000111>
<obo:IAO_0000115>A bacterial mating type indicating the presence of F plasmid in a bacterial cell.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>F mating type</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001348 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001348">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001335"/>
<obo:IAO_0000111>F minus mating type</obo:IAO_0000111>
<obo:IAO_0000115>A bacterial mating type indicating the absence of F plasmid in a bacterial cell.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>F minus mating type</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001374 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001374">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001396"/>
<obo:IAO_0000111>ploidy</obo:IAO_0000111>
<obo:IAO_0000115>A cellular quality inhering in a bearer by virtue of the bearer's number of homologous sets of chromosomes in the nucleus or primary chromosome-containing compartment of the cell, each set essentially coding for all the biological traits of the organism.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>ploidy</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001375 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001375">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001393"/>
<obo:IAO_0000111>haploid</obo:IAO_0000111>
<obo:IAO_0000115>A ploidy quality inhering in a bearer by virtue of the bearer's containing a single set of homologous chromosomes.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>haploid</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001377 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001377">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001393"/>
<obo:IAO_0000111>polyploid</obo:IAO_0000111>
<obo:IAO_0000115>A ploidy quality inhering in a bearer by virtue of the bearer's containing more than two homologous sets of chromosomes.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>polyploid</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001385 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001385">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001374"/>
<obo:IAO_0000111>aneuploid</obo:IAO_0000111>
<obo:IAO_0000115>A ploidy quality inhering in a bearer by virtue of the bearer's containing a non-integral multiple of the monoploid number, due to extra or missing chromosomes.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>aneuploid</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001393 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001393">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001374"/>
<obo:IAO_0000111>euploid</obo:IAO_0000111>
<obo:IAO_0000115>A ploidy quality inhering in a bearer by virtue of the bearer's containing an integral multiple of the monoploid number, possibly excluding the sex-determining chromosomes.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>euploid</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001394 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001394">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001393"/>
<obo:IAO_0000111>diploid</obo:IAO_0000111>
<obo:IAO_0000115>A ploidy quality inhering in a bearer by virtue of the bearer's having two copies (homologs) of each chromosome, usually one from the mother and one from the father.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>diploid</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001396 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001396">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0070044"/>
<obo:IAO_0000111>cellular quality</obo:IAO_0000111>
<obo:IAO_0000115>A monadic quality of continuant that exists at the cellular level of organisation.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>cellular quality</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001421 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001421">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0000169"/>
<obo:IAO_0000111>alive</obo:IAO_0000111>
<obo:IAO_0000115>A viability quality inhering in a bearer by virtue of the bearer's condition before death.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>alive</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001422 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001422">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0000169"/>
<obo:IAO_0000111>dead</obo:IAO_0000111>
<obo:IAO_0000115>A viability quality inhering in a bearer by virtue of the cessation of the bearer's life.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>dead</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001546 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001546">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0002198"/>
<obo:IAO_0000111>quality of a solid</obo:IAO_0000111>
<obo:IAO_0000115>A physical quality inhering in a bearer by virtue of the bearer's exhibiting the physical characteristics of an entity characterized by particles arranged such that their shape and volume are relatively stable.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>quality of a solid</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001547 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001547">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0002198"/>
<obo:IAO_0000111>quality of a gas</obo:IAO_0000111>
<obo:IAO_0000115>A physical quality inhering in a bearer by virtue of the bearer's exhibiting the physical characteristics of an entity consisting of particles that have neither a defined volume nor defined shape.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>quality of a gas</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001548 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001548">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0002198"/>
<obo:IAO_0000111>quality of a liquid</obo:IAO_0000111>
<obo:IAO_0000115>A physical quality inhering in an entity exhibiting the physical characteristics of an amorphous (non-crystalline) form of matter between a gas and a solid that has a definite volume, but no definite shape.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>quality of a liquid</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001574 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001574">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001906"/>
<obo:IAO_0000111>flow rate</obo:IAO_0000111>
<obo:IAO_0000115>A physical quality inhering in a bearer by virtue of the bearer's motion characteristic.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>flow rate</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001632 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001632">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0000140"/>
<obo:IAO_0000111>anterior to</obo:IAO_0000111>
<obo:IAO_0000115>A spatial quality inhering in a bearer by virtue of the bearer's being located toward the front of an organism relative to another entity.</obo:IAO_0000115>
<obo:IAO_0000118 xml:lang="en">frontal</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>anterior to</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001708 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001708">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0000117"/>
<obo:IAO_0000111>1-D extent</obo:IAO_0000111>
<obo:IAO_0000115>A size quality inhering in an bearer by virtue of the bearer's extension in one dimension.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>1-D extent</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001710 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001710">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0000117"/>
<obo:IAO_0000111>3-D extent</obo:IAO_0000111>
<obo:IAO_0000115>A size quality inhering in an bearer by virtue of the bearer's extension in three dimensions.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>3-D extent</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001740 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001740">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0002198"/>
<obo:IAO_0000111>activity (of a radionuclide)</obo:IAO_0000111>
<obo:IAO_0000115>A radiation quality inhering in a radioactive substance by virtue of its transformation (disintegration) rate.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>activity (of a radionuclide)</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001741 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001741">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001740"/>
<obo:IAO_0000111>radioactive</obo:IAO_0000111>
<obo:IAO_0000115>A radiation quality inhering in bearer by virtue of the bearer's exhibiting or being caused by radioactivity.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>radioactive</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001792 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001792">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0000140"/>
<obo:IAO_0000111>left side of</obo:IAO_0000111>
<obo:IAO_0000115>A spatial quality inhering in a bearer by virtue of the bearer's being located on left side of from the a another entity.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>left side of</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001793 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001793">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0000140"/>
<obo:IAO_0000111>right side of</obo:IAO_0000111>
<obo:IAO_0000115>A spatial quality inhering in a bearer by virtue of the bearer's being located on right side of a another entity.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>right side of</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001894 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001894">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0000047"/>
<obo:IAO_0000111>phenotypic sex</obo:IAO_0000111>
<obo:IAO_0000115>An organismal quality inhering in a bearer by virtue of the bearer's physical expression of sexual characteristics.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>phenotypic sex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001895 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001895">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0000047"/>
<obo:IAO_0000111>mating type</obo:IAO_0000111>
<obo:IAO_0000115>A biological sex quality inhering in an individual or a population that undergo sexual reproduction.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>mating type</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001906 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001906">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001018"/>
<obo:IAO_0000111>movement quality</obo:IAO_0000111>
<obo:IAO_0000115>A physical quality inhering in a bearer by virtue of the bearer's participation in movement.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>movement quality</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001985 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001985">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0000146"/>
<obo:IAO_0000111>frozen</obo:IAO_0000111>
<obo:IAO_0000115>A quality inhering in a bearer by virtue of the bearer's being kept below its freezing point.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>frozen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001995 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001995">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001241"/>
<obo:IAO_0000111>organismal quality</obo:IAO_0000111>
<obo:IAO_0000115>A quality that inheres in an entire organism or part of an organism.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>organismal quality</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0002003 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0002003">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001241"/>
<obo:IAO_0000111>population quality</obo:IAO_0000111>
<obo:IAO_0000115>A quality that inheres in an entire population or part of a population.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>population quality</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0002027 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0002027">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0000033"/>
<obo:IAO_0000111>osmolality</obo:IAO_0000111>
<obo:IAO_0000115>A concentration quality inhering in a bearer by virtue of the bearer's amount of osmoles of solute per kilogram of solvent.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>osmolality</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0002198 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0002198">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001018"/>
<obo:IAO_0000111>quality of a substance</obo:IAO_0000111>
<obo:IAO_0000115>A quality inhering in a bearer by virtue of its constitution.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>quality of a substance</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0002201 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0002201">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0000186"/>
<obo:IAO_0000111>handedness</obo:IAO_0000111>
<obo:IAO_0000115>A behavioral quality inhering ina bearer by virtue of the bearer's unequal distribution of fine motor skill between its left and right hands or feet.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>handedness</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0002202 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0002202">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0002201"/>
<obo:IAO_0000111>left handedness</obo:IAO_0000111>
<obo:IAO_0000115>Handedness where the organism preferentially uses the left hand or foot for tasks requiring the use of a single hand or foot or a dominant hand or foot.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>left handedness</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0002203 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0002203">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0002201"/>
<obo:IAO_0000111>right handedness</obo:IAO_0000111>
<obo:IAO_0000115>Handedness where the organism preferentially uses the right hand or foot for tasks requiring the use of a single hand or foot or a dominant hand or foot.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>right handedness</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0002204 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0002204">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0002201"/>
<obo:IAO_0000111>ambidextrous handedness</obo:IAO_0000111>
<obo:IAO_0000115>Handedness where the organism exhibits no overall dominance in the use of right or left hand or foot in the performance of tasks that require one hand or foot or a dominant hand or foot.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>ambidextrous handedness</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0002243 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0002243">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001574"/>
<obo:IAO_0000111>fluid flow rate</obo:IAO_0000111>
<obo:IAO_0000115>A physical quality inhering in a fluid (liquid or gas) by virtue of the amount of fluid which passes through a given surface per unit time.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>fluid flow rate</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0070044 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0070044">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001241"/>
<obo:IAO_0000111>anatomical structure quality</obo:IAO_0000111>
<obo:IAO_0000115>A quality of continuant that exist at the anatomical level of organisation and anything under it. This includes, but is not limited to, cells , tissues, and components.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>anatomical structure quality</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0070060 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0070060">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0002198"/>
<obo:IAO_0000111>quality of interaction of a substance with electromagnetic radiation</obo:IAO_0000111>
<obo:IAO_0000115>A quality of a substance on which or through which electromagnetic radiation impinges or traverses with respect to radiation. This substance quality changes the quality of the incident radiation with respect to any of: intensity, direction, scatter and wavelength.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>quality of interaction of a substance with electromagnetic radiation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0103000 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0103000">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0000001"/>
<obo:IAO_0000111>quantitative</obo:IAO_0000111>
<obo:IAO_0000115>A quality of an entity that can be represented numerically, including anything that can be counted, measured, or given a numerical value.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
<rdfs:label>quantitative</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PR_000000001 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000000001">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16670"/>
<obo:IAO_0000111>protein</obo:IAO_0000111>
<obo:IAO_0000112>antithrombin III is a protein</obo:IAO_0000112>
<obo:IAO_0000115>An amino acid chain that is produced de novo by ribosome-mediated translation of a genetically-encoded mRNA, and any derivatives thereof.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
<rdfs:label>protein</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PR_000001004 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000001004">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
<obo:IAO_0000111>CD4 molecule</obo:IAO_0000111>
<obo:IAO_0000115>A protein that is a translation product of the human CD4 gene or a 1:1 ortholog thereof. CD4 is an accessory protein for MHC class-II antigen/T-cell receptor interaction. It is the primary receptor for HIV-1. CD4 has four immunoglobulin-like domains in its extracellular region that share the same structure, but can differ in sequence.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
<rdfs:label>CD4 molecule</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PR_000001018 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000001018">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
<obo:IAO_0000111>CD3 subunit with immunoglobulin domain</obo:IAO_0000111>
<obo:IAO_0000115>A protein that has a core domain composition consisting of an extracellular N-terminal domain that adopts an immunoglobulin fold, a transmembrane domain, and an intracellular C-terminal domain with a single copy of the Immunoreceptor tyrosine-based activation motif (Pfam:PF02189) (ITAM). It constitutes the invariant subunit of the T cell antigen receptor (TCR). TCR is a surface receptor on T cells responsible for recognizing MHC-restricted antigens and initiating the cellular immune response.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
<rdfs:label>CD3 subunit with immunoglobulin domain</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PR_000003015 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000003015">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
<obo:IAO_0000111>prostate-specific antigen</obo:IAO_0000111>
<obo:IAO_0000115>A trypsin that is a translation product of the human KLK3 gene or a 1:1 ortholog thereof.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
<rdfs:label>prostate-specific antigen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PR_000003252 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000003252">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
<obo:IAO_0000111>antithrombin-III</obo:IAO_0000111>
<obo:IAO_0000115>A serpin that is a translation product of the human SERPINC1 gene or a 1:1 ortholog thereof.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
<rdfs:label>antithrombin-III</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PR_000003745 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000003745">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
<obo:IAO_0000111>double-stranded RNA-specific adenosine deaminase</obo:IAO_0000111>
<obo:IAO_0000115>A protein that is a translation product of the human ADAR gene or a 1:1 ortholog thereof.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
<rdfs:label>double-stranded RNA-specific adenosine deaminase</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PR_000003777 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000003777">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
<obo:IAO_0000111>adiponectin</obo:IAO_0000111>
<obo:IAO_0000115>A protein that is a translation product of the human ADIPOQ gene or a 1:1 ortholog thereof.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
<rdfs:label>adiponectin</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PR_000003918 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000003918">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
<obo:IAO_0000111>albumin</obo:IAO_0000111>
<obo:IAO_0000115>A protein that is a translation product of the human ALB gene or a 1:1 ortholog thereof.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
<rdfs:label>albumin</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PR_000004580 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000004580">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
<obo:IAO_0000111>beta-2-microglobulin</obo:IAO_0000111>
<obo:IAO_0000115>A protein that is a translation product of the human B2M gene or a 1:1 ortholog thereof.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
<rdfs:label>beta-2-microglobulin</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PR_000005794 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000005794">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
<obo:IAO_0000111>ceruloplasmin</obo:IAO_0000111>
<obo:IAO_0000115>A protein that is a translation product of the human CP gene or a 1:1 ortholog thereof.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
<rdfs:label>ceruloplasmin</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PR_000005897 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000005897">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
<obo:IAO_0000111>C-reactive protein</obo:IAO_0000111>
<obo:IAO_0000115>A protein that is a translation product of the human CRP gene or a 1:1 ortholog thereof.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
<rdfs:label>C-reactive protein</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PR_000006592 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000006592">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
<obo:IAO_0000111>deoxyribonuclease-1</obo:IAO_0000111>
<obo:IAO_0000115>A protein that is a translation product of the human DNASE1 gene or a 1:1 ortholog thereof.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
<rdfs:label>deoxyribonuclease-1</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PR_000007141 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000007141">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
<obo:IAO_0000111>erythropoietin</obo:IAO_0000111>
<obo:IAO_0000115>A protein that is a translation product of the human EPO gene or a 1:1 ortholog thereof.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
<rdfs:label>erythropoietin</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PR_000007928 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000007928">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
<obo:IAO_0000111>glial cell line-derived neurotrophic factor</obo:IAO_0000111>
<obo:IAO_0000115>A protein that is a translation product of the human GDNF gene or a 1:1 ortholog thereof.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
<rdfs:label>glial cell line-derived neurotrophic factor</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PR_000008457 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000008457">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
<obo:IAO_0000111>beta-globin</obo:IAO_0000111>
<obo:IAO_0000115>A hemoglobin subunit that is a translation product of the human HBB gene, a 1:1 ortholog thereof, or pro-orthologs thereof.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
<rdfs:label>beta-globin</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PR_000008725 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000008725">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
<obo:IAO_0000111>haptoglobin</obo:IAO_0000111>
<obo:IAO_0000115>A protein that is a translation product of the human HP gene or a 1:1 ortholog thereof.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
<rdfs:label>haptoglobin</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PR_000009758 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000009758">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
<obo:IAO_0000111>leptin</obo:IAO_0000111>
<obo:IAO_0000115>A protein that is a translation product of the human LEP gene or a 1:1 ortholog thereof.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
<rdfs:label>leptin</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PR_000013429 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000013429">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
<obo:IAO_0000111>parathyroid hormone</obo:IAO_0000111>
<obo:IAO_0000115>A protein that is a translation product of the human PTH gene or a 1:1 ortholog thereof.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
<rdfs:label>parathyroid hormone</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PR_000014060 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000014060">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
<obo:IAO_0000111>ribonuclease T2</obo:IAO_0000111>
<obo:IAO_0000115>A protein that is a translation product of the human RNASET2 gene or a 1:1 ortholog thereof.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
<rdfs:label>ribonuclease T2</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PR_000016261 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000016261">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
<obo:IAO_0000111>serotransferrin</obo:IAO_0000111>
<obo:IAO_0000115>A protein that is a translation product of the human TF gene or a 1:1 ortholog thereof.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
<rdfs:label>serotransferrin</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PR_000016801 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000016801">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
<obo:IAO_0000111>transthyretin</obo:IAO_0000111>
<obo:IAO_0000115>A protein that is a translation product of the human TTR gene or a 1:1 ortholog thereof.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
<rdfs:label>transthyretin</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PR_000023089 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000023089">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000427"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0003824"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000111>DNA ligase</obo:IAO_0000111>
<obo:IAO_0000115>A protein that is a translation product of the Escherichia coli K-12 ligA gene or a 1:1 ortholog thereof.</obo:IAO_0000115>
<obo:IAO_0000116>Definition defined by OBI developers: an enzyme that covalently joins two compatible pieces of DNA through the cleavage of an ATP molecule</obo:IAO_0000116>
<obo:IAO_0000118>ligase</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
<rdfs:label>DNA ligase</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PR_000025402 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000025402">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
<obo:IAO_0000111>T cell receptor co-receptor CD8</obo:IAO_0000111>
<obo:IAO_0000115>A protein-containing complex that is a membrane-bound heterodimeric co-receptor for MHC class-I antigen/T-cell receptor interaction.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
<rdfs:label>T cell receptor co-receptor CD8</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PR_000025467 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000025467">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
<obo:IAO_0000111>guanyl-specific ribonuclease T1</obo:IAO_0000111>
<obo:IAO_0000115>A protein that is a translation product of the Aspergillus oryzae RIB40 rntA gene or a 1:1 ortholog thereof.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
<rdfs:label>guanyl-specific ribonuclease T1</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PR_000025471 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000025471">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
<obo:IAO_0000111>nuclease S1</obo:IAO_0000111>
<obo:IAO_0000115>A protein that is a translation product of the Aspergillus oryzae RIB40 nucS gene or a 1:1 ortholog thereof.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
<rdfs:label>nuclease S1</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PR_000025475 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000025475">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
<obo:IAO_0000111>ribonuclease U2</obo:IAO_0000111>
<obo:IAO_0000115>A protein that is a translation product of the Ustilago sphaerogena RNU2 gene or a 1:1 ortholog thereof.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
<rdfs:label>ribonuclease U2</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PR_000025477 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000025477">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
<obo:IAO_0000111>ribonuclease V1 (cobra)</obo:IAO_0000111>
<obo:IAO_0000115>A protein with ribonuclease activity that is a constituent of cobra venom.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
<rdfs:label>ribonuclease V1 (cobra)</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PR_000025478 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000025478">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
<obo:IAO_0000111>ribonuclease CL3 (chicken)</obo:IAO_0000111>
<obo:IAO_0000115>A protein with ribonuclease activity that is purified from chicken liver.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
<rdfs:label>ribonuclease CL3 (chicken)</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PR_000027247 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000027247">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0032991"/>
<obo:IAO_0000111>cytosolic creatine kinase complex, MB-type</obo:IAO_0000111>
<obo:IAO_0000115>A cytosolic creatine kinase complex that is a heterodimer of a B-type subunit and an M-type subunit.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
<rdfs:label>cytosolic creatine kinase complex, MB-type</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PR_000029971 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000029971">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
<obo:IAO_0000111>creatine kinase</obo:IAO_0000111>
<obo:IAO_0000115>A protein that contains a single ATP:guanido phosphotransferase N-terminal domain (Pfam:PF02807) followed by a single ATP:guanido phosphotransferase C-terminal catalytic domain (Pfam:PF00217).</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
<rdfs:label>creatine kinase</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PR_000029983 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000029983">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
<obo:IAO_0000111>protein-glutamine gamma-glutamyltransferase</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
<rdfs:label>protein-glutamine gamma-glutamyltransferase</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PR_000036824 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000036824">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
<obo:IAO_0000111>NS1</obo:IAO_0000111>
<obo:IAO_0000115>A dengue virus genome polyprotein proteolytic cleavage product that is the N-terminal most non-structural protein within the dengue virus genome polyprotein. Example: UniProtKB:P29990, 776-1127, Asn-905/Asn-982, MOD:00160.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
<rdfs:label>NS1</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PR_000050219 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000050219">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
<obo:IAO_0000111>alanine aminotransferase</obo:IAO_0000111>
<obo:IAO_0000115>A protein that is a translation product of the human GPT or GPT2 genes, 1:1 orthologs thereof, or a semi-ortholog thereof.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
<rdfs:label>alanine aminotransferase</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PR_000050331 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000050331">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0032991"/>
<obo:IAO_0000111>lactate dehydrogenase complex</obo:IAO_0000111>
<obo:IAO_0000115>A protein-containing complex that is composed of four subunits of L-lactate dehydrogenase, cytoplasmic.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
<rdfs:label>lactate dehydrogenase complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PR_000050343 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000050343">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
<obo:IAO_0000111>alkaline phosphatase (human)</obo:IAO_0000111>
<obo:IAO_0000115>A protein that is a translation product of any of the following alkaline phosphatase genes in human: ALPG (encoding the germinal form; GCAP), ALPP (encoding the placental form; PLAP), ALPI (encoding the intestinal form; IAP), and ALPL (encoding the tissue non-specific form; TNAP).</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
<rdfs:label>alkaline phosphatase (human)</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PR_000050353 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000050353">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
<obo:IAO_0000111>aspartate aminotransferase (human)</obo:IAO_0000111>
<obo:IAO_0000115>A protein that is a translation product of any of the following genes in human: GOT1/GOT2.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
<rdfs:label>aspartate aminotransferase (human)</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PR_000050469 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000050469">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0032991"/>
<obo:IAO_0000111>hemoglobin A1c</obo:IAO_0000111>
<obo:IAO_0000115>A hemoglobin complex that is composed of at least one beta-N-1-deoxy fructosyl hemoglobin subunit, in which the glycan is attached to the N-terminal valine (after initiator methionine removal) of one or both beta subunits.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
<rdfs:label>hemoglobin A1c</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/REO_0000171 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/REO_0000171">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A reagent role inhering in a molecular entity intended to associate with some molecular target to serve as a proxy for the presence, abundance, or location of this target in a detection of molecular label assay.</obo:IAO_0000115>
<obo:IAO_0000117>Group: OBI</obo:IAO_0000117>
<obo:IAO_0000118>molecular tracer role</obo:IAO_0000118>
<obo:IAO_0000119>OBI developer call, 3-12-12</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/OBI_0002743"/>
<rdfs:label>obsolete molecular label role</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/REO_0000280 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/REO_0000280">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A molecular reagent intended to associate with some molecular target to serve as a proxy for the presence, abundance, or location of this target in a detection of molecular label assay</obo:IAO_0000115>
<obo:IAO_0000117>Group: OBI</obo:IAO_0000117>
<obo:IAO_0000118>molecular tracer</obo:IAO_0000118>
<obo:IAO_0000119>OBI developer call, 3-12-12</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/OBI_0002744"/>
<rdfs:label>obsolete molecular label</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/SO_0000001 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/SO_0000001">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000031"/>
<obo:IAO_0000111>region</obo:IAO_0000111>
<obo:IAO_0000115>A sequence_feature with an extent greater than zero. A nucleotide region is composed of bases and a polypeptide region is composed of amino acids.</obo:IAO_0000115>
<obo:IAO_0000118>primary structure of sequence macromolecule</obo:IAO_0000118>
<obo:IAO_0000118>sequence</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/so.owl"/>
<rdfs:label>region</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/SO_0000104 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/SO_0000104">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/SO_0000001"/>
<obo:IAO_0000111>polypeptide</obo:IAO_0000111>
<obo:IAO_0000115>A sequence of amino acids linked by peptide bonds which may lack appreciable tertiary structure and may not be liable to irreversible denaturation.</obo:IAO_0000115>
<obo:IAO_0000118>polypeptide sequence</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/so.owl"/>
<rdfs:label>polypeptide</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/SO_0000148 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/SO_0000148">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/SO_0000353"/>
<obo:IAO_0000111>supercontig</obo:IAO_0000111>
<obo:IAO_0000115>One or more contigs that have been ordered and oriented using end-read information. Contains gaps that are filled with N's.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/so.owl"/>
<rdfs:label>supercontig</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/SO_0000149 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/SO_0000149">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/SO_0000353"/>
<obo:IAO_0000111>contig</obo:IAO_0000111>
<obo:IAO_0000115>A contiguous sequence derived from sequence assembly. Has no gaps, but may contain N's from unavailable bases.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/so.owl"/>
<rdfs:label>contig</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/SO_0000235 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/SO_0000235">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/SO_0005836"/>
<obo:IAO_0000111>TF_binding_site</obo:IAO_0000111>
<obo:IAO_0000115>A DNA site where a transcription factor binds.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/so.owl"/>
<rdfs:label>TF_binding_site</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/SO_0000276 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/SO_0000276">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/SO_0000001"/>
<obo:IAO_0000111>miRNA</obo:IAO_0000111>
<obo:IAO_0000115>Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene (or the product of other non coding RNA genes). Micro RNAs are produced from precursor molecules (SO:0001244) that can form local hairpin structures, which ordinarily are processed (usually via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/so.owl"/>
<rdfs:label>miRNA</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/SO_0000353 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/SO_0000353">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/SO_0001248"/>
<obo:IAO_0000111>sequence_assembly</obo:IAO_0000111>
<obo:IAO_0000115>A sequence of nucleotides that has been algorithmically derived from an alignment of two or more different sequences.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/so.owl"/>
<rdfs:label>sequence_assembly</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/SO_0000988 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/SO_0000988">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001241"/>
<obo:IAO_0000111>circular</obo:IAO_0000111>
<obo:IAO_0000115>A quality of a nucleotide polymer that has no terminal nucleotide residues.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/so.owl"/>
<rdfs:label>circular</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/SO_0001248 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/SO_0001248">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/SO_0001410"/>
<obo:IAO_0000111>assembly</obo:IAO_0000111>
<obo:IAO_0000115>A region of the genome of known length that is composed by ordering and aligning two or more different regions.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/so.owl"/>
<rdfs:label>assembly</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/SO_0001410 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/SO_0001410">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/SO_0000001"/>
<obo:IAO_0000111>experimental_feature</obo:IAO_0000111>
<obo:IAO_0000115>A region which is the result of some arbitrary experimental procedure. The procedure may be carried out with biological material or inside a computer.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/so.owl"/>
<rdfs:label>experimental_feature</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/SO_0005836 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/SO_0005836">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/SO_0000001"/>
<obo:IAO_0000111>regulatory_region</obo:IAO_0000111>
<obo:IAO_0000115>A region of sequence that is involved in the control of a biological process.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/so.owl"/>
<rdfs:label>regulatory_region</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0000002 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000002">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>uterine cervix</obo:IAO_0000111>
<obo:IAO_0000115>Lower, narrow portion of the uterus where it joins with the top end of the vagina.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>uterine cervix</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0000007 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000007">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>pituitary gland</obo:IAO_0000111>
<obo:IAO_0000115>The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands [GO]. An endocrine gland located ventral to the diencephalon and derived from mixed neuroectodermal and non neuroectodermal origin [ZFIN].</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>pituitary gland</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0000010 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000010">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>peripheral nervous system</obo:IAO_0000111>
<obo:IAO_0000115>A major division of the nervous system that contains nerves which connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>peripheral nervous system</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0000029 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000029">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>lymph node</obo:IAO_0000111>
<obo:IAO_0000115>Any of the rounded masses of lymphoid tissue that are surrounded by a capsule of connective tissue, are distributed along the lymphatic vessels, and contain numerous lymphocytes which filter the flow of lymph.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>lymph node</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0000057 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000057">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>urethra</obo:IAO_0000111>
<obo:IAO_0000115>The fibromuscular tubular canal through which urine is discharged from the bladder to the exterior via the external urinary meatus; in males, the urethra is joined by the ejaculatory ducts and serves as a passageway for semen during ejaculation, as well as a canal for urine during voiding; in females, the urethra is shorter and emerges above the vaginal opening.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>urethra</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0000105 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000105">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<obo:IAO_0000111>life cycle stage</obo:IAO_0000111>
<obo:IAO_0000115>A spatiotemporal region encompassing some part of the life cycle of an organism.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>life cycle stage</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0000162 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000162">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>cloaca</obo:IAO_0000111>
<obo:IAO_0000115>Common chamber into which the intestines and excretory system opens. Arises during development in all vertebrates, but in many it becomes subdivided, lost or incorporated into other structures.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>cloaca</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0000165 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000165">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>mouth</obo:IAO_0000111>
<obo:IAO_0000115>The proximal portion of the digestive tract, containing the oral cavity and bounded by the oral opening. In vertebrates, this extends to the pharynx and includes gums, lips, tongue and parts of the palate. Typically also includes the teeth, except where these occur elsewhere (e.g. pharyngeal jaws) or protrude from the mouth (tusks).</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>mouth</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0000173 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000173">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000463"/>
<obo:IAO_0000111>amniotic fluid</obo:IAO_0000111>
<obo:IAO_0000115>Amniotic fluid is a bodily fluid consisting of watery liquid surrounding and cushioning a growing fetus within the amnion. It allows the fetus to move freely without the walls of the uterus being too tight against its body. Buoyancy is also provided. The composition of the fluid changes over the course of gestation. Initially, amniotic fluid is similar to maternal plasma, mainly water with electrolytes. As the fetus develops, proteins, carbohydrates, lipids, phospholipids originating from the lungs, fetal cells, and urea are deposited in the fluid.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>amniotic fluid</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0000178 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000178">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0006314"/>
<obo:IAO_0000111>blood</obo:IAO_0000111>
<obo:IAO_0000115>A fluid that is composed of blood plasma and erythrocytes.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>blood</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0000305 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000305">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>amnion</obo:IAO_0000111>
<obo:IAO_0000115>The thin innermost layer of the extraembryonic membranes that contains the amniotic fluid; the membrane forms a closed sac in which the embryo and later, the fetus, is suspended and protected.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>amnion</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0000310 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000310">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>breast</obo:IAO_0000111>
<obo:IAO_0000115>The upper ventral region of the torso of an organism.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>breast</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0000316 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000316">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0006314"/>
<obo:IAO_0000111>cervical mucus</obo:IAO_0000111>
<obo:IAO_0000115>A substance produced by the cervix and endocervical glands[BTO]. Thick acidic mucus that blocks the cervical os after mestruation[WP]. This 'infertile' mucus blocks spermatozoa from entering the uterus.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>cervical mucus</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0000341 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000341">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>throat</obo:IAO_0000111>
<obo:IAO_0000115>In anatomy, the throat is the anterior part of the neck, in front of the vertebral column. It consists of the pharynx and larynx. An important feature of the throat is the epiglottis, a flap which separates the esophagus from the trachea and prevents inhalation of food or drink. The throat contains various blood vessels, various pharyngeal muscles, the trachea (windpipe) and the esophagus. The hyoid bone and the clavicle are the only bones located in the throat of mammals. It is sometimes considered a synonym for fauces. [WP,unvetted].</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>throat</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0000362 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000362">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000481"/>
<obo:IAO_0000111>renal medulla</obo:IAO_0000111>
<obo:IAO_0000115>The inner portion of the kidney consisting of the renal pyramids.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>renal medulla</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0000463 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000463">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>organism substance</obo:IAO_0000111>
<obo:IAO_0000115>Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>organism substance</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0000465 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000465">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000111>material anatomical entity</obo:IAO_0000111>
<obo:IAO_0000115>Anatomical entity that has mass.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>material anatomical entity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0000473 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000473">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>testis</obo:IAO_0000111>
<obo:IAO_0000115>A gonad of a male animal. A gonad produces and releases sperm.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>testis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0000477 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000477">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000111>anatomical cluster</obo:IAO_0000111>
<obo:IAO_0000115>Anatomical group whose component anatomical structures lie in close proximity to each other.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>anatomical cluster</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0000479 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000479">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>tissue</obo:IAO_0000111>
<obo:IAO_0000115>Multicellular anatomical structure that consists of many cells of one or a few types, arranged in an extracellular matrix such that their long-range organisation is at least partly a repetition of their short-range organisation.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>tissue</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0000481 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000481">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>multi-tissue structure</obo:IAO_0000111>
<obo:IAO_0000115>Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona-fide boundaries from other distinct structural units of different types.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>multi-tissue structure</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0000483 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000483">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<obo:IAO_0000111>epithelium</obo:IAO_0000111>
<obo:IAO_0000115>Portion of tissue, that consists of one or more layers of epithelial cells connected to each other by cell junctions and which is underlain by a basal lamina. Examples: simple squamous epithelium, glandular cuboidal epithelium, transitional epithelium, myoepithelium[CARO].</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>epithelium</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0000945 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000945">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>stomach</obo:IAO_0000111>
<obo:IAO_0000115>An expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ. A stomach is lined, in whole or in part by a glandular epithelium.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>stomach</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0000947 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000947">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>aorta</obo:IAO_0000111>
<obo:IAO_0000115>The main trunk of the systemic arterial system that carries blood from the heart to all the organs and other structures of the body, bringing oxygenated blood to all parts of the body in the systemic circulation.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>aorta</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0000948 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000948">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>heart</obo:IAO_0000111>
<obo:IAO_0000115>A myogenic muscular circulatory organ found in the vertebrate cardiovascular system composed of chambers of cardiac muscle. It is the primary circulatory organ.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>heart</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0000955 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000955">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>brain</obo:IAO_0000111>
<obo:IAO_0000115>The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as jellyfish and starfish have a decentralized nervous system without a brain, while sponges lack any nervous system at all. In vertebrates, the brain is located in the head, protected by the skull and close to the primary sensory apparatus of vision, hearing, balance, taste, and smell[WP].</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>brain</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0000956 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000956">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>cerebral cortex</obo:IAO_0000111>
<obo:IAO_0000115>The thin layer of gray matter on the surface of the cerebral hemisphere that develops from the telencephalon. It consists of the neocortex (6 layered cortex or isocortex), the hippocampal formation and the olfactory cortex.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>cerebral cortex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0000970 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000970">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>eye</obo:IAO_0000111>
<obo:IAO_0000115>An organ that detects light.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>eye</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0000978 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000978">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>leg</obo:IAO_0000111>
<obo:IAO_0000115>The portion of the hindlimb that contains both the stylopod and zeugopod.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>leg</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0000992 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000992">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>ovary</obo:IAO_0000111>
<obo:IAO_0000115>The gonad of a female organism which contains germ cells.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>ovary</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0000995 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000995">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>uterus</obo:IAO_0000111>
<obo:IAO_0000115>The female muscular organ of gestation in which the developing embryo or fetus is nourished until birth.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>uterus</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0000996 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000996">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>vagina</obo:IAO_0000111>
<obo:IAO_0000115>A fibromuscular tubular tract leading from the uterus to the exterior of the body in female placental mammals and marsupials, or to the cloaca in female birds, monotremes, and some reptiles[WP].</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>vagina</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001003 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001003">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000483"/>
<obo:IAO_0000111>skin epidermis</obo:IAO_0000111>
<obo:IAO_0000115>The outer epithelial layer of the skin that is superficial to the dermis.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>skin epidermis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001004 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001004">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>respiratory system</obo:IAO_0000111>
<obo:IAO_0000115>Functional system which consists of structures involved in respiration.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>respiratory system</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001013 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001013">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<obo:IAO_0000111>adipose tissue</obo:IAO_0000111>
<obo:IAO_0000115>Portion of connective tissue composed of adipocytes enmeshed in areolar tissue.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>adipose tissue</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001037 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001037">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>strand of hair</obo:IAO_0000111>
<obo:IAO_0000115>A filament, mostly protein, that grows from follicles found in the dermis[WP].</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>strand of hair</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001052 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001052">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>rectum</obo:IAO_0000111>
<obo:IAO_0000115>The terminal portion of the intestinal tube, terminating with the anus.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>rectum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001087 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001087">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0006314"/>
<obo:IAO_0000111>pleural fluid</obo:IAO_0000111>
<obo:IAO_0000115>Transudate contained in the pleural cavity.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>pleural fluid</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001088 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001088">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000463"/>
<obo:IAO_0000111>urine</obo:IAO_0000111>
<obo:IAO_0000115>Excretion that is the output of a kidney.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>urine</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001089 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001089">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0006314"/>
<obo:IAO_0000111>sweat</obo:IAO_0000111>
<obo:IAO_0000115>Secretion produced by a sweat gland.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>sweat</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001090 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001090">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0006314"/>
<obo:IAO_0000111>synovial fluid</obo:IAO_0000111>
<obo:IAO_0000115>Joint fluid is a transudate of plasma that is actively secreted by synovial cells.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>synovial fluid</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001103 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001103">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>diaphragm</obo:IAO_0000111>
<obo:IAO_0000115>A thin musculomebranous barrier that separates the abdominal and thoracic cavities. Often used for breathing control.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>diaphragm</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001134 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001134">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<obo:IAO_0000111>skeletal muscle tissue</obo:IAO_0000111>
<obo:IAO_0000115>Muscle tissue that consists primarily of skeletal muscle fibers.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>skeletal muscle tissue</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001155 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001155">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>colon</obo:IAO_0000111>
<obo:IAO_0000115>A portion of the large intestine before it becomes the rectum. In mammals, the colon is the most part of the large intestine, excluding the vermiform appendix, the rectum and the anal canal.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>colon</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001159 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001159">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>sigmoid colon</obo:IAO_0000111>
<obo:IAO_0000115>The part of the large intestine that is closest to the rectum and anus. It forms a loop that averages about 40 cm. in length, and normally lies within the pelvis, but on account of its freedom of movement it is liable to be displaced into the abdominal cavity.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>sigmoid colon</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001225 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001225">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>cortex of kidney</obo:IAO_0000111>
<obo:IAO_0000115>Outer cortical portion of the kidney, between the renal capsule and the renal medulla.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>cortex of kidney</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001255 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001255">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>urinary bladder</obo:IAO_0000111>
<obo:IAO_0000115>Distensible musculomembranous organ situated in the anterior part of the pelvic cavity in which urine collects before excretion[MP].</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>urinary bladder</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001264 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001264">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>pancreas</obo:IAO_0000111>
<obo:IAO_0000115>An endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating hormones[GO].</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>pancreas</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001268 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001268">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0006314"/>
<obo:IAO_0000111>peritoneal fluid</obo:IAO_0000111>
<obo:IAO_0000115>Transudate contained in the peritoneal cavity.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>peritoneal fluid</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001323 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001323">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>tibial nerve</obo:IAO_0000111>
<obo:IAO_0000115>The tibial nerve is a branch of the sciatic nerve. The tibial nerve passes through the popliteal fossa to pass below the arch of soleus. In the popliteal fossa the nerve gives off branches to gastrocnemius, popliteus, soleus and plantaris muscles, an articular branch to the knee joint, and a cutaneous branch that will become the sural nerve. The sural nerve is joined by fibres from the common peroneal nerve and runs down the calf to supply the lateral side of the foot. Below the soleus muscle the nerve lies close to the tibia and supplies the tibialis posterior, the flexor digitorum longus and the flexor hallucis longus. The nerve passes into the foot running posterior to the medial malleolus. Here it is bound down by the flexor retinaculum in company with the posterior tibial artery. [WP,unvetted].</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>tibial nerve</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001359 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001359">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0006314"/>
<obo:IAO_0000111>cerebrospinal fluid</obo:IAO_0000111>
<obo:IAO_0000115>A clear, colorless, bodily fluid, that occupies the subarachnoid space and the ventricular system around and inside the brain and spinal cord.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>cerebrospinal fluid</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001460 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001460">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>arm</obo:IAO_0000111>
<obo:IAO_0000115>The part of the forelimb extending from the shoulder to the autopod[cjm].</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>arm</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001485 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001485">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>knee joint</obo:IAO_0000111>
<obo:IAO_0000115>The knee joint joins the thigh with the leg and consists of two articulations: one between the femur and tibia, and one between the femur and patella. It is the largest and most complicated joint in the human body. The knee is a mobile trocho-ginglymus (i.e. a pivotal hinge joint), which permits flexion and extension as well as a slight medial and lateral rotation[WP,unvetted].</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>knee joint</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001488 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001488">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>ankle joint</obo:IAO_0000111>
<obo:IAO_0000115>A joint that connects the hindlimb autopod and zeugopod skeletons.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>ankle joint</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001530 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001530">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001637"/>
<obo:IAO_0000111>common carotid artery plus branches</obo:IAO_0000111>
<obo:IAO_0000115>A bilaterally paired branched artery that originates from the aortic arches and divides into and includes as parts the internal and external carotid arteries[cjm].</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>common carotid artery plus branches</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001555 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001555">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>digestive tract</obo:IAO_0000111>
<obo:IAO_0000115>A tube extending from the mouth to the anus.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>digestive tract</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001557 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001557">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>upper respiratory tract</obo:IAO_0000111>
<obo:IAO_0000115>The segment of the respiratory tract that starts proximally with the nose and ends distally with the cricoid cartilage, before continuing to the trachea.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>upper respiratory tract</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001558 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001558">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>lower respiratory tract</obo:IAO_0000111>
<obo:IAO_0000115>The segment of the respiratory tract that starts proximally with the trachea and includes all distal structures including the lungs[WP,modified].</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>lower respiratory tract</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001567 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001567">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>cheek</obo:IAO_0000111>
<obo:IAO_0000115>A fleshy subdivision of one side of the face bounded by an eye, ear and the nose.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>cheek</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001577 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001577">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>facial muscle</obo:IAO_0000111>
<obo:IAO_0000115>A muscle innervated by a facial nerve.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>facial muscle</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001621 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001621">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001637"/>
<obo:IAO_0000111>coronary artery</obo:IAO_0000111>
<obo:IAO_0000115>An artery that supplies the myocardium.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>coronary artery</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001637 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001637">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>artery</obo:IAO_0000111>
<obo:IAO_0000115>An epithelial tube or tree of tibes that transports blood away from the heart[modified from AEO definition].</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>artery</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001638 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001638">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>vein</obo:IAO_0000111>
<obo:IAO_0000115>Any of the tubular branching vessels that carry blood from the capillaries toward the heart.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>vein</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001723 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001723">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>tongue</obo:IAO_0000111>
<obo:IAO_0000115>A muscular organ in the floor of the mouth.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>tongue</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001728 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001728">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>nasopharynx</obo:IAO_0000111>
<obo:IAO_0000115>The section of the pharynx that lies above the soft palate.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>nasopharynx</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001729 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001729">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>oropharynx</obo:IAO_0000111>
<obo:IAO_0000115>The portion of the pharynx that lies between the soft palate and the upper edge of the epiglottis.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>oropharynx</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001797 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001797">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000463"/>
<obo:IAO_0000111>vitreous humor</obo:IAO_0000111>
<obo:IAO_0000115>A transparent, semigelatinous substance that fills the cavity behind the crystalline lens of the eye and in front of the retina.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>vitreous humor</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001811 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001811">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>conjunctiva</obo:IAO_0000111>
<obo:IAO_0000115>The mucous membrane that lines the inner surface of the eyelids and the front of the eyeball.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>conjunctiva</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001826 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001826">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>nasal cavity mucosa</obo:IAO_0000111>
<obo:IAO_0000115>The mucous membrane that lines the nasal cavity[MP].</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>nasal cavity mucosa</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001830 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001830">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>minor salivary gland</obo:IAO_0000111>
<obo:IAO_0000115>One of the smaller, largely mucus-secreting, exocrine glands of the oral cavity, consisting of the labial, buccal, molar, lingual, and palatine glands[MP].</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>minor salivary gland</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001836 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001836">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000463"/>
<obo:IAO_0000111>saliva</obo:IAO_0000111>
<obo:IAO_0000115>A fluid produced in the oral cavity by salivary glands, typically used in predigestion, but also in other functions.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>saliva</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001873 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001873">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>caudate nucleus</obo:IAO_0000111>
<obo:IAO_0000115>Subcortical nucleus of telecephalic origin consisting of an elongated gray mass lying lateral to and bordering the lateral ventricle. It is divided into a head, body and tail in some species.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>caudate nucleus</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001874 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001874">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>putamen</obo:IAO_0000111>
<obo:IAO_0000115>Subcortical nucleus of telencephalic , which together with the caudate nucleus, forms the striatum. The putamen lies lateral to the internal capsule and medial to the external medullary lamina, and is separated from the caudate nucleus by the fibers of the internal capsule for most of its length, except at its anterior portion.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>putamen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001893 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001893">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000481"/>
<obo:IAO_0000111>telencephalon</obo:IAO_0000111>
<obo:IAO_0000115>Part of the forebrain consisting of paired olfactory bulbs and cerebral hemispheres.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>telencephalon</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001913 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001913">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0006314"/>
<obo:IAO_0000111>milk</obo:IAO_0000111>
<obo:IAO_0000115>An emulsion of fat globules within a fluid that is secreted by the mammary gland during lactation.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>milk</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001968 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001968">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000463"/>
<obo:IAO_0000111>semen</obo:IAO_0000111>
<obo:IAO_0000115>Organism substance that is composed of sperm cells suspended in seminal fluid.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>semen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001970 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001970">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0006314"/>
<obo:IAO_0000111>bile</obo:IAO_0000111>
<obo:IAO_0000115>Vital aqueous secretion of the liver that is formed by hepatocytes and modified down stream by absorptive and secretory properties of the bile duct epithelium.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>bile</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001987 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001987">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>placenta</obo:IAO_0000111>
<obo:IAO_0000115>Organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin[GO]. The fetal portion of the placenta is known as the villous chorion. The maternal portion is known as the decidua basalis. The two portions are held together by anchoring villi that are anchored to the decidua basalis by the cytotrophoblastic shell.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>placenta</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0001988 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001988">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000463"/>
<obo:IAO_0000111>feces</obo:IAO_0000111>
<obo:IAO_0000115>Portion of semisolid bodily waste discharged through the anus[MW,modified].</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>feces</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0002032 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002032">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>areola</obo:IAO_0000111>
<obo:IAO_0000115>Subdivision of breast which consists of skin, connective tissue and smooth muscle bundle and modified sebaceous glands and which surrounds the nipple.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>areola</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0002037 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002037">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000481"/>
<obo:IAO_0000111>cerebellum</obo:IAO_0000111>
<obo:IAO_0000115>Part of the metencephalon that lies in the posterior cranial fossa behind the brain stem. It is concerned with the coordination of movement[MESH]. A large dorsally projecting part of the brain concerned especially with the coordination of muscles and the maintenance of bodily equilibrium, situated between the brain stem and the back of the cerebrum , and formed in humans of two lateral lobes and a median lobe[BTO]. Brain structure derived from the anterior hindbrain, and perhaps including posterior midbrain. The cerebellum plays a role in somatic motor function, the control of muscle tone, and balance[ZFA].</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>cerebellum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0002046 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002046">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>thyroid gland</obo:IAO_0000111>
<obo:IAO_0000115>A two-lobed endocrine gland found in all vertebrates, located in front of and on either side of the trachea in humans, and producing various hormones, such as triiodothyronine and calcitonin[BTO].</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>thyroid gland</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0002048 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002048">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>lung</obo:IAO_0000111>
<obo:IAO_0000115>Respiration organ that develops as an outpocketing of the esophagus.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>lung</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0002067 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002067">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>dermis</obo:IAO_0000111>
<obo:IAO_0000115>The dermis is a layer of skin between the epidermis (with which it makes up the skin) and subcutaneous tissues, and is composed of two layers, the papillary and reticular dermis[WP].</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>dermis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0002072 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002072">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>hypodermis</obo:IAO_0000111>
<obo:IAO_0000115>Lowermost layer of the integumentary system in vertebrates. Types of cells that are found in the hypodermis are fibroblasts, adipose cells, and macrophages. It is derived from the mesoderm, but unlike the dermis, it is not derived from the dermatome region of the mesoderm. The hypodermis is used mainly for fat storage[WP].</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>hypodermis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0002097 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002097">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>skin of body</obo:IAO_0000111>
<obo:IAO_0000115>The organ covering the body that consists of the dermis and epidermis.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>skin of body</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0002106 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002106">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>spleen</obo:IAO_0000111>
<obo:IAO_0000115>The organ that functions to filter blood and to store red corpuscles and platelets.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>spleen</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0002107 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002107">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>liver</obo:IAO_0000111>
<obo:IAO_0000115>An exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes[GO].</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>liver</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0002116 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002116">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>ileum</obo:IAO_0000111>
<obo:IAO_0000115>The portion of the small intestine that extends from the jejunum to the colon.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>ileum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0002199 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002199">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>integument</obo:IAO_0000111>
<obo:IAO_0000115>The dermis, epidermis and hypodermis.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>integument</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0002358 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002358">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000481"/>
<obo:IAO_0000111>peritoneum</obo:IAO_0000111>
<obo:IAO_0000115>A serous membrane that lines the peritoneal cavity[VHOG,modified].</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>peritoneum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0002367 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002367">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>prostate gland</obo:IAO_0000111>
<obo:IAO_0000115>The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>prostate gland</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0002369 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002369">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>adrenal gland</obo:IAO_0000111>
<obo:IAO_0000115>Either of a pair of complex endocrine organs near the anterior medial border of the kidney consisting of a mesodermal cortex that produces glucocorticoid, mineralocorticoid, and androgenic hormones and an ectodermal medulla that produces epinephrine and norepinephrine[BTO].</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>adrenal gland</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0002371 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002371">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<obo:IAO_0000111>bone marrow</obo:IAO_0000111>
<obo:IAO_0000115>The soft tissue that fills the cavities of bones.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>bone marrow</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0002386 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002386">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>forelimb zeugopod</obo:IAO_0000111>
<obo:IAO_0000115>The middle limb segment of the pectoral free limb, between the autopod and stylopod segments. Includes as parts the forelimb zeugopodial skeleton, which includes as parts the radius and ulna, or their cartilage precursors, or evolutionary variants.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>forelimb zeugopod</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0002389 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002389">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>manual digit</obo:IAO_0000111>
<obo:IAO_0000115>A digit that is part of a manus (hand).</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>manual digit</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0002391 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002391">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0006314"/>
<obo:IAO_0000111>lymph</obo:IAO_0000111>
<obo:IAO_0000115>Lymph is the fluid that is formed when interstitial fluid enters the conduits of the lymphatic system through lymph capillaries[WP].</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>lymph</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0002409 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002409">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0006314"/>
<obo:IAO_0000111>pericardial fluid</obo:IAO_0000111>
<obo:IAO_0000115>Transudate contained in the pericardial cavity.[FMA].</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>pericardial fluid</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0002415 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002415">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>tail</obo:IAO_0000111>
<obo:IAO_0000115>An external caudal extension of the body. In chordates, the tail is post-anal, in other animals the anus ends in the tail.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>tail</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0002465 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002465">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>lymphoid system</obo:IAO_0000111>
<obo:IAO_0000115>The lymphatic system in vertebrates is a network of conduits that carry a clear fluid called lymph. It also includes the lymphoid tissue through which the lymph travels. Lymphoid tissue is found in many organs, particularly the lymph nodes, and in the lymphoid follicles associated with the digestive system such as the tonsils. The system also includes all the structures dedicated to the circulation and production of lymphocytes, which includes the spleen, thymus, bone marrow and the lymphoid tissue associated with the digestive system[WP].</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>lymphoid system</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0002469 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002469">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>esophagus mucosa</obo:IAO_0000111>
<obo:IAO_0000115>A mucosa that is part of a esophagus [Automatically generated definition].</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>esophagus mucosa</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0002812 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002812">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>left cerebral hemisphere</obo:IAO_0000111>
<obo:IAO_0000115>A cerebral hemisphere that is in the left side of a brain.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>left cerebral hemisphere</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0002813 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002813">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>right cerebral hemisphere</obo:IAO_0000111>
<obo:IAO_0000115>A cerebral hemisphere that is in the right side of a brain.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>right cerebral hemisphere</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0003126 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0003126">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>trachea</obo:IAO_0000111>
<obo:IAO_0000115>The trachea is the portion of the airway that attaches to the bronchi as it branches [GO:dph].</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>trachea</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0003128 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0003128">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>cranium</obo:IAO_0000111>
<obo:IAO_0000115>Upper portion of the skull that excludes the mandible (when present in the organism).</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>cranium</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0003688 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0003688">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>omentum</obo:IAO_0000111>
<obo:IAO_0000115>A fold of peritoneum originating at the stomach and supporting the viscera.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>omentum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0004648 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0004648">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<obo:IAO_0000111>esophagus muscularis mucosa</obo:IAO_0000111>
<obo:IAO_0000115>A muscularis mucosa that is part of a esophagus.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>esophagus muscularis mucosa</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0005022 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0005022">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>mucosa of nasopharynx</obo:IAO_0000111>
<obo:IAO_0000115>A mucosa that is part of a nasopharynx [Automatically generated definition].</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>mucosa of nasopharynx</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0005023 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0005023">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>mucosa of oropharynx</obo:IAO_0000111>
<obo:IAO_0000115>A mucosa that is part of a oropharynx [Automatically generated definition].</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>mucosa of oropharynx</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0005921 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0005921">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>middle nasal concha</obo:IAO_0000111>
<obo:IAO_0000115>The medial surface of the labyrinth of ethmoid consists of a thin lamella, which descends from the under surface of the cribriform plate, and ends below in a free, convoluted margin, the middle nasal concha. It is rough, and marked above by numerous grooves, directed nearly vertically downward from the cribriform plate; they lodge branches of the olfactory nerves, which are distributed to the mucous membrane covering the superior nasal concha.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>middle nasal concha</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0006314 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0006314">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000463"/>
<obo:IAO_0000111>bodily fluid</obo:IAO_0000111>
<obo:IAO_0000115>Liquid components of living organisms. includes fluids that are excreted or secreted from the body as well as body water that normally is not.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>bodily fluid</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0006538 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0006538">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000463"/>
<obo:IAO_0000111>respiratory system fluid/secretion</obo:IAO_0000111>
<obo:IAO_0000115>A portion of organism substance that secreted_by a respiratory system.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>respiratory system fluid/secretion</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0006618 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0006618">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000481"/>
<obo:IAO_0000111>atrium auricular region</obo:IAO_0000111>
<obo:IAO_0000115>A small conical pouch projections located on the upper anterior portion of each atrium of the heart.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>atrium auricular region</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0006911 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0006911">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000463"/>
<obo:IAO_0000111>digestive system secreted substance</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>digestive system secreted substance</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0007106 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0007106">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>chorionic villus</obo:IAO_0000111>
<obo:IAO_0000115>One of the minute vascular projections of the fetal chorion that combines with maternal uterine tissue to form the placenta.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>chorionic villus</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0007109 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0007109">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001988"/>
<obo:IAO_0000111>meconium</obo:IAO_0000111>
<obo:IAO_0000115>A dark greenish mass that accumulates in the bowel during fetal life and is discharged shortly after birth.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>meconium</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0007311 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0007311">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0006538"/>
<obo:IAO_0000111>sputum</obo:IAO_0000111>
<obo:IAO_0000115>Matter ejected from the lungs, bronchi, and trachea, through the mouth.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>sputum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0007610 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0007610">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001637"/>
<obo:IAO_0000111>tibial artery</obo:IAO_0000111>
<obo:IAO_0000115>The anterior and posterior arteries created at the bifurcation of the popliteal artery. The anterior tibial artery begins at the lower border of the popliteus muscle and lies along the tibia at the distal part of the leg to surface superficially anterior to the ankle joint. Its branches are distributed throughout the leg, ankle, and pes. The posterior tibial artery begins at the lower border of the popliteus muscle, lies behind the tibia in the lower part of its course, and is found situated between the medial malleolus and the medial process of the calcaneal tuberosity. Its branches are distributed throughout the leg and foot.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>tibial artery</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0007650 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0007650">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>esophagogastric junction</obo:IAO_0000111>
<obo:IAO_0000115>The junction between the esophagus and the stomach epithelium.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>esophagogastric junction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0008188 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0008188">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000479"/>
<obo:IAO_0000111>tendon of biceps brachii</obo:IAO_0000111>
<obo:IAO_0000115>A tendon that attaches_to a biceps brachii.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>tendon of biceps brachii</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0010414 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0010414">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001013"/>
<obo:IAO_0000111>omental fat pad</obo:IAO_0000111>
<obo:IAO_0000115>Encapsulated adipose tissue associated with the fold of peritoneal tissue that extends from the stomach to the posterior abdominal wall after associating with the transverse colon.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>omental fat pad</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0011011 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0011011">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>brachioradialis</obo:IAO_0000111>
<obo:IAO_0000115>Brachioradialis is a muscle of the forearm that acts to flex the forearm at the elbow. It is also capable of both pronation and supination, depending on the position of the forearm. It is attached to the distal styloid process of the radius by way of the brachioradialis tendon, and to the lateral supracondylar ridge of the humerus.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>brachioradialis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0012168 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0012168">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0013755"/>
<obo:IAO_0000111>umbilical cord blood</obo:IAO_0000111>
<obo:IAO_0000115>Blood that remains in the placenta and in the attached umbilical cord after childbirth[WP].</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>umbilical cord blood</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0013755 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0013755">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000178"/>
<obo:IAO_0000111>arterial blood</obo:IAO_0000111>
<obo:IAO_0000115>A blood that is part of a artery.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>arterial blood</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0013756 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0013756">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000178"/>
<obo:IAO_0000111>venous blood</obo:IAO_0000111>
<obo:IAO_0000115>A blood that is part of a vein.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>venous blood</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0013757 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0013757">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000178"/>
<obo:IAO_0000111>capillary blood</obo:IAO_0000111>
<obo:IAO_0000115>A blood that is part of a capillary.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>capillary blood</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_0036149 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0036149">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>suprapubic skin</obo:IAO_0000111>
<obo:IAO_0000115>Area of skin in the hypoastric region of the abdomen.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>suprapubic skin</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_3000016 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_3000016">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
<obo:IAO_0000111>anterior nasal wall</obo:IAO_0000111>
<obo:IAO_0000115>Paired, vertical, and relatively straight plates that form the anterior limit of the nasal capsule.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>anterior nasal wall</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UBERON_8470000 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_8470000">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000178"/>
<obo:IAO_0000111>placental blood</obo:IAO_0000111>
<obo:IAO_0000115>Blood located in the placenta.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
<rdfs:label>placental blood</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UO_0000001 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UO_0000001">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000003"/>
<obo:IAO_0000111>length unit</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>length unit</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UO_0000002 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UO_0000002">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000003"/>
<obo:IAO_0000111>mass unit</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>mass unit</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UO_0000003 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UO_0000003">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000003"/>
<obo:IAO_0000111>time unit</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>time unit</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UO_0000005 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UO_0000005">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000003"/>
<obo:IAO_0000111>temperature unit</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>temperature unit</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UO_0000006 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UO_0000006">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000003"/>
<obo:IAO_0000111>substance unit</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>substance unit</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UO_0000051 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UO_0000051">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000003"/>
<obo:IAO_0000111>concentration unit</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>concentration unit</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UO_0000095 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UO_0000095">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000003"/>
<obo:IAO_0000111>volume unit</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>volume unit</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UO_0000105 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UO_0000105">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000003"/>
<obo:IAO_0000111>frequency unit</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>frequency unit</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UO_0000109 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UO_0000109">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000003"/>
<obo:IAO_0000111>pressure unit</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>pressure unit</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UO_0000270 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UO_0000270">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000003"/>
<obo:IAO_0000111>volumetric flow rate unit</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>volumetric flow rate unit</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/UO_0000280 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/UO_0000280">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000003"/>
<obo:IAO_0000111>rate unit</obo:IAO_0000111>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>rate unit</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/VO_0000001 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000001">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000111>vaccine</obo:IAO_0000111>
<obo:IAO_0000115>Material entity that is manufactured to realize the vaccine function.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/vo.owl"/>
<rdfs:label>vaccine</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/VO_0000002 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000002">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600007"/>
<obo:IAO_0000111>vaccination</obo:IAO_0000111>
<obo:IAO_0000115>A process of administering a vaccine in vivo to a recipient (e.g., human) with the intent to invoke a protective or therapeutic adaptive immune response.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/vo.owl"/>
<rdfs:label>vaccination</rdfs:label>
</owl:Class>
<!-- http://www.geneontology.org/formats/oboInOwl#ObsoleteClass -->
<owl:Class rdf:about="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<rdfs:label>Obsolete Class</rdfs:label>
</owl:Class>
<!-- http://www.w3.org/2002/07/owl#Thing -->
<owl:Class rdf:about="http://www.w3.org/2002/07/owl#Thing"/>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Individuals
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!-- http://purl.obolibrary.org/obo/GAZ_00000448 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/GAZ_00000448"/>
<!-- http://purl.obolibrary.org/obo/IAO_0000002 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000002">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000078"/>
<obo:IAO_0000111 xml:lang="en">example to be eventually removed</obo:IAO_0000111>
<rdfs:label xml:lang="en">example to be eventually removed</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/IAO_0000103 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000103">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000225"/>
<obo:IAO_0000111 xml:lang="en">failed exploratory term</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">The term was used in an attempt to structure part of the ontology but in retrospect failed to do a good job</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000117>
<rdfs:label xml:lang="en">failed exploratory term</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/IAO_0000120 -->
<owl:Thing rdf:about="http://purl.obolibrary.org/obo/IAO_0000120">
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#NamedIndividual"/>
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000078"/>
<obo:IAO_0000111 xml:lang="en">metadata complete</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">Class has all its metadata, but is either not guaranteed to be in its final location in the asserted IS_A hierarchy or refers to another class that is not complete.</obo:IAO_0000115>
<rdfs:label xml:lang="en">metadata complete</rdfs:label>
</owl:Thing>
<!-- http://purl.obolibrary.org/obo/IAO_0000121 -->
<owl:Thing rdf:about="http://purl.obolibrary.org/obo/IAO_0000121">
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#NamedIndividual"/>
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000078"/>
<obo:IAO_0000111 xml:lang="en">organizational term</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">Term created to ease viewing/sort terms for development purpose, and will not be included in a release</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Alan Ruttenberg</obo:IAO_0000117>
<rdfs:label xml:lang="en">organizational term</rdfs:label>
</owl:Thing>
<!-- http://purl.obolibrary.org/obo/IAO_0000122 -->
<owl:Thing rdf:about="http://purl.obolibrary.org/obo/IAO_0000122">
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#NamedIndividual"/>
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000078"/>
<obo:IAO_0000111 xml:lang="en">ready for release</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">Class has undergone final review, is ready for use, and will be included in the next release. Any class lacking "ready_for_release" should be considered likely to change place in hierarchy, have its definition refined, or be obsoleted in the next release. Those classes deemed "ready_for_release" will also derived from a chain of ancestor classes that are also "ready_for_release."</obo:IAO_0000115>
<rdfs:label xml:lang="en">ready for release</rdfs:label>
</owl:Thing>
<!-- http://purl.obolibrary.org/obo/IAO_0000123 -->
<owl:Thing rdf:about="http://purl.obolibrary.org/obo/IAO_0000123">
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#NamedIndividual"/>
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000078"/>
<obo:IAO_0000111 xml:lang="en">metadata incomplete</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">Class is being worked on; however, the metadata (including definition) are not complete or sufficiently clear to the branch editors.</obo:IAO_0000115>
<rdfs:label xml:lang="en">metadata incomplete</rdfs:label>
</owl:Thing>
<!-- http://purl.obolibrary.org/obo/IAO_0000124 -->
<owl:Thing rdf:about="http://purl.obolibrary.org/obo/IAO_0000124">
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#NamedIndividual"/>
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000078"/>
<obo:IAO_0000111 xml:lang="en">uncurated</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">Nothing done yet beyond assigning a unique class ID and proposing a preferred term.</obo:IAO_0000115>
<rdfs:label xml:lang="en">uncurated</rdfs:label>
</owl:Thing>
<!-- http://purl.obolibrary.org/obo/IAO_0000125 -->
<owl:Thing rdf:about="http://purl.obolibrary.org/obo/IAO_0000125">
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#NamedIndividual"/>
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000078"/>
<obo:IAO_0000111 xml:lang="en">pending final vetting</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">All definitions, placement in the asserted IS_A hierarchy and required minimal metadata are complete. The class is awaiting a final review by someone other than the term editor.</obo:IAO_0000115>
<rdfs:label xml:lang="en">pending final vetting</rdfs:label>
</owl:Thing>
<!-- http://purl.obolibrary.org/obo/IAO_0000224 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000224">
<obo:IAO_0000115 xml:lang="en">Core is an instance of a grouping of terms from an ontology or ontologies. It is used by the ontology to identify main classes.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">PERSON: Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">PERSON: Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000226"/>
<rdfs:label xml:lang="en">obsolete_core</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/IAO_0000226 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000226">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000225"/>
<obo:IAO_0000111 xml:lang="en">placeholder removed</obo:IAO_0000111>
<rdfs:label xml:lang="en">placeholder removed</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/IAO_0000227 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000227">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000225"/>
<obo:IAO_0000111 xml:lang="en">terms merged</obo:IAO_0000111>
<obo:IAO_0000116 xml:lang="en">An editor note should explain what were the merged terms and the reason for the merge.</obo:IAO_0000116>
<rdfs:label xml:lang="en">terms merged</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/IAO_0000228 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000228">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000225"/>
<obo:IAO_0000111 xml:lang="en">term imported</obo:IAO_0000111>
<obo:IAO_0000116 xml:lang="en">This is to be used when the original term has been replaced by a term imported from an other ontology. An editor note should indicate what is the URI of the new term to use.</obo:IAO_0000116>
<rdfs:label xml:lang="en">term imported</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/IAO_0000229 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000229">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000225"/>
<obo:IAO_0000111 xml:lang="en">term split</obo:IAO_0000111>
<obo:IAO_0000116 xml:lang="en">This is to be used when a term has been split in two or more new terms. An editor note should indicate the reason for the split and indicate the URIs of the new terms created.</obo:IAO_0000116>
<rdfs:label xml:lang="en">term split</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/IAO_0000410 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000410">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000409"/>
<obo:IAO_0000111 xml:lang="en">universal</obo:IAO_0000111>
<obo:IAO_0000116 xml:lang="en">Hard to give a definition for. Intuitively a "natural kind" rather than a collection of any old things, which a class is able to be, formally. At the meta level, universals are defined as positives, are disjoint with their siblings, have single asserted parents.</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">A Formal Theory of Substances, Qualities, and Universals, http://ontology.buffalo.edu/bfo/SQU.pdf</obo:IAO_0000119>
<rdfs:label xml:lang="en">universal</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/IAO_0000420 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000420">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000409"/>
<obo:IAO_0000111 xml:lang="en">defined class</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A defined class is a class that is defined by a set of logically necessary and sufficient conditions but is not a universal</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">"definitions", in some readings, always are given by necessary and sufficient conditions. So one must be careful (and this is difficult sometimes) to distinguish between defined classes and universal.</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Alan Ruttenberg</obo:IAO_0000117>
<rdfs:label xml:lang="en">defined class</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/IAO_0000421 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000421">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000409"/>
<obo:IAO_0000111 xml:lang="en">named class expression</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A named class expression is a logical expression that is given a name. The name can be used in place of the expression.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">named class expressions are used in order to have more concise logical definition but their extensions may not be interesting classes on their own. In languages such as OWL, with no provisions for macros, these show up as actuall classes. Tools may with to not show them as such, and to replace uses of the macros with their expansions</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Alan Ruttenberg</obo:IAO_0000117>
<rdfs:label xml:lang="en">named class expression</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/IAO_0000423 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000423">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000078"/>
<obo:IAO_0000111 xml:lang="en">to be replaced with external ontology term</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">Terms with this status should eventually replaced with a term from another ontology.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">group:OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">to be replaced with external ontology term</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/IAO_0000428 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000428">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000078"/>
<obo:IAO_0000111 xml:lang="en">requires discussion</obo:IAO_0000111>
<obo:IAO_0000115 xml:lang="en">A term that is metadata complete, has been reviewed, and problems have been identified that require discussion before release. Such a term requires editor note(s) to identify the outstanding issues.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">group:OBI</obo:IAO_0000119>
<rdfs:label xml:lang="en">requires discussion</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000317 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000317">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000098"/>
<obo:IAO_0000111 xml:lang="en">Transformation-ML</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Transformation-ML file describing parameter transformations used in a GvHD experiment.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">Transformation-ML is a format standard of a digital entity that is conformant with the Transformation-ML standard.(http://wiki.ficcs.org/ficcs/Transformation-ML?action=AttachFile&do=get&target=Transformation-ML_v1.0.26.pdf)</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">person:Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000119>web-page:http://wiki.ficcs.org/ficcs/Transformation-ML?action=AttachFile&do=get&target=Transformation-ML_v1.0.26.pdf</obo:IAO_0000119>
<rdfs:label xml:lang="en">Transformation-ML</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000321 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000321">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000098"/>
<obo:IAO_0000111 xml:lang="en">ACS</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">d06.acs, ACS1.0 data file of well D06 of plate 2 of part 1 of a GvHD experiment.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">ACS is a format standard of a digital entity that is conformant with the Analytical Cytometry Standard. (http://www.isac-net.org/content/view/607/150/)</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">person:Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000119>web-page:http://www.isac-net.org/content/view/607/150/</obo:IAO_0000119>
<rdfs:label xml:lang="en">ACS</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000322 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000322">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000098"/>
<obo:IAO_0000111 xml:lang="en">XML</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">RDF/XML file, OWL file, Compensation-ML file, WSDL document, SVG document</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">XML is a format standard of a digital entity that is conformant with the W3C Extensible Markup Language Recommendation.(http://www.w3.org/XML/)</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">person:Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000119>web-page:http://www.w3.org/XML/</obo:IAO_0000119>
<rdfs:label xml:lang="en">XML</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000324 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000324">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000098"/>
<obo:IAO_0000111 xml:lang="en">RDF</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">A FOAF file, a SKOS file, an OWL file.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">RDF is a format standard of a digital entity that is conformant with the W3C Resource Description Framework RDF/XML Syntax specification.(http://www.w3.org/RDF/)</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">person:Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000119>web-page:http://www.w3.org/RDF/</obo:IAO_0000119>
<rdfs:label xml:lang="en">RDF</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000325 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000325">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000098"/>
<obo:IAO_0000111 xml:lang="en">zip</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">MagicDraw MDZIP archive, Java JAR file.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">zip is a format standard of a digital entity that is conformant with the PKWARE .ZIP file format specification (http://www.pkware.com/index.php?option=com_content&task=view&id=59&Itemid=103/)</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">person:Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000119>web-page:http://www.pkware.com/index.php?option=com_content&task=view&id=59&Itemid=103/</obo:IAO_0000119>
<rdfs:label xml:lang="en">zip</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000326 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000326">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000098"/>
<obo:IAO_0000111 xml:lang="en">tar</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">Example.tar file.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">tar is a format standard of a digital entity that is conformant with the tape archive file format as standardized by POSIX.1-1998, POSIX.1-2001, or any other tar format compliant with the GNU tar specification. (http://www.gnu.org/software/tar/manual/)</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">person:Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000119>web-page:http://www.gnu.org/software/tar/manual/</obo:IAO_0000119>
<rdfs:label xml:lang="en">tar</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000327 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000327">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000098"/>
<obo:IAO_0000111 xml:lang="en">FCS</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">d01.fcs, FCS3 data file of well D06 of plate 2 of part 1 of a GvHD experiment.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">FCS is a format standard of a digital entity that is conformant with the Flow Cytometry Data File Standard.(http://www.fcspress.com/)</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">person:Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000119>web-page:http://www.fcspress.com/</obo:IAO_0000119>
<rdfs:label xml:lang="en">FCS</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000329 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000329">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000098"/>
<obo:IAO_0000111 xml:lang="en">Compensation-ML</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">compfoo.xml, Compensation-ML file describing compensation used in a GvHD experiment</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">Compensation-ML is a format standard of a digital entity that is conformant with the Compensation-ML standard. (http://wiki.ficcs.org/ficcs/Compensation-ML?action=AttachFile&do=get&target=Compensation-ML_v1.0.24.pdf)</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">person:Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000119>web-page:http://wiki.ficcs.org/ficcs/Compensation-ML?action=AttachFile&do=get&target=Compensation-ML_v1.0.24.pdf</obo:IAO_0000119>
<rdfs:label xml:lang="en">Compensation-ML</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000330 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000330">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000098"/>
<obo:IAO_0000111 xml:lang="en">Gating-ML</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">foogate.xml, Gating-ML file describing gates used in a GvHD experiment.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">Gating-ML is a format standard of a digital entity that is conformant with the Gating-ML standard. (http://www.flowcyt.org/gating/)</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">person:Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000119>web-page:http://www.flowcyt.org/gating/</obo:IAO_0000119>
<rdfs:label xml:lang="en">Gating-ML</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000332 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000332">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000098"/>
<obo:IAO_0000111 xml:lang="en">OWL</obo:IAO_0000111>
<obo:IAO_0000112 xml:lang="en">OBI ontology file, Basic Formal Ontology file, BIRNLex file, BioPAX file.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">OWL is a format standard of a digital entity that is conformant with the W3C Web Ontology Language specification.(http://www.w3.org/2004/OWL/)</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">person:Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000119>web-page:http://www.w3.org/2004/OWL/</obo:IAO_0000119>
<rdfs:label xml:lang="en">OWL</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000461 -->
<owl:Thing rdf:about="http://purl.obolibrary.org/obo/OBI_0000461">
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#NamedIndividual"/>
<obo:IAO_0000111>obsolete_the supplier role of Affymetrix</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_the supplier role of Affymetrix</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Thing>
<!-- http://purl.obolibrary.org/obo/OBI_0000462 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000462">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002989"/>
<obo:IAO_0000111>Affymetrix</obo:IAO_0000111>
<obo:IAO_0000112>Affymetrix supplied microarray</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An organization which supplies technology, tools and protocols for use in high throughput applications</obo:IAO_0000115>
<rdfs:label>Affymetrix</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000752 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000752">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>Thermo</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<rdfs:label>Thermo</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000753 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000753">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>Waters</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<rdfs:label>Waters</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000754 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000754">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>BIO-RAD</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<rdfs:label>BIO-RAD</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000755 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000755">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0200042"/>
<obo:IAO_0000111>GenePattern hierarchical clustering</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<rdfs:label>GenePattern hierarchical clustering</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000756 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000756">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>Ambion</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<rdfs:label>Ambion</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000757 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000757">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>Helicos</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<rdfs:label>Helicos</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000758 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000758">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>Roche</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<rdfs:label>Roche</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000759 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000759">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>Illumina</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<rdfs:label>Illumina</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000760 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000760">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0200051"/>
<obo:IAO_0000111>GenePattern PCA</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<rdfs:label>GenePattern PCA</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000761 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000761">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000713"/>
<obo:IAO_0000136 rdf:resource="http://purl.obolibrary.org/obo/OBI_0000775"/>
<obo:IAO_0000111>GenePattern module SVM</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">GenePattern module SVM is a GenePattern software module which is used to run a support vector machine data transformation.</obo:IAO_0000115>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<obo:IAO_0000117>Ryan Brinkman</obo:IAO_0000117>
<rdfs:label>GenePattern module SVM</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000762 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000762">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000727"/>
<obo:IAO_0000111>GenePattern k-nearest neighbors</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<rdfs:label>GenePattern k-nearest neighbors</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000763 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000763">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0200033"/>
<obo:IAO_0000111>GenePattern LOOCV</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<rdfs:label>GenePattern LOOCV</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000764 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000764">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0200041"/>
<obo:IAO_0000111>GenePattern k-means clustering</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<rdfs:label>GenePattern k-means clustering</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000765 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000765">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>Agilent</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<rdfs:label>Agilent</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000766 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000766">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000713"/>
<obo:IAO_0000136 rdf:resource="http://purl.obolibrary.org/obo/OBI_0000764"/>
<obo:IAO_0000111>GenePattern module KMeansClustering</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">GenePattern module KMeansClustering is a GenePattern software module which is used to perform a k Means clustering data transformation.</obo:IAO_0000115>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: James Malone</obo:IAO_0000119>
<rdfs:label>GenePattern module KMeansClustering</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000767 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000767">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000749"/>
<obo:IAO_0000111>GenePattern CART</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<rdfs:label>GenePattern CART</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000768 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000768">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000713"/>
<obo:IAO_0000136 rdf:resource="http://purl.obolibrary.org/obo/OBI_0000763"/>
<obo:IAO_0000136 rdf:resource="http://purl.obolibrary.org/obo/OBI_0000767"/>
<obo:IAO_0000111>GenePattern module CARTXValidation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">GenePattern module CARTXValidation is a GenePattern software module which uses a CART decision tree induction with a leave one out cross validation data transformations.</obo:IAO_0000115>
<rdfs:label>GenePattern module CARTXValidation</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000769 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000769">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>Li-Cor</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<rdfs:label>Li-Cor</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000770 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000770">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>Bruker Corporation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<rdfs:label>Bruker Corporation</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000771 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000771">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000713"/>
<obo:IAO_0000111>GenePattern module KNNXValidation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">GenePattern module KNNXValidation is a GenePattern software module which uses a k-nearest neighbours clustering with a leave one out cross validation data transformations.</obo:IAO_0000115>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: James Malone</obo:IAO_0000119>
<rdfs:label>GenePattern module KNNXValidation</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000772 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000772">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000713"/>
<obo:IAO_0000136 rdf:resource="http://purl.obolibrary.org/obo/OBI_0000778"/>
<obo:IAO_0000111>GenePattern module PeakMatch</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<rdfs:label>GenePattern module PeakMatch</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000773 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000773">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000713"/>
<obo:IAO_0000136 rdf:resource="http://purl.obolibrary.org/obo/OBI_0000762"/>
<obo:IAO_0000111>GenePattern module KNN</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">GenePattern module KNN is a GenePattern software module which perform a k-nearest neighbors data transformation.</obo:IAO_0000115>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<rdfs:label>GenePattern module KNN</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000774 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000774">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000713"/>
<obo:IAO_0000136 rdf:resource="http://purl.obolibrary.org/obo/OBI_0000755"/>
<obo:IAO_0000111>GenePattern module HierarchicalClustering</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">GenePattern module HierarchicalClustering is a GenePattern software module which is used to perform a hierarchical clustering data transformation.</obo:IAO_0000115>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: James Malone</obo:IAO_0000117>
<rdfs:label>GenePattern module HierarchicalClustering</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000775 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000775">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000700"/>
<obo:IAO_0000111>GenePattern SVM</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<rdfs:label>GenePattern SVM</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000776 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000776">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>Applied Biosystems</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<rdfs:label>Applied Biosystems</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000777 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000777">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000713"/>
<obo:IAO_0000136 rdf:resource="http://purl.obolibrary.org/obo/OBI_0000760"/>
<obo:IAO_0000111>GenePattern module PCA</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">GenePattern module PCA is a GenePattern software module which is used to perform a principal components analysis dimensionality reduction data transformation.</obo:IAO_0000115>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<obo:IAO_0000119>PERSON: James Malone</obo:IAO_0000119>
<rdfs:label>GenePattern module PCA</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000778 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000778">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000726"/>
<obo:IAO_0000111>GenePattern peak matching</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<obo:IAO_0000117>Ryan Brinkman</obo:IAO_0000117>
<rdfs:label>GenePattern peak matching</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000779 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000779">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>Bruker Daltonics</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<rdfs:label>Bruker Daltonics</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000780 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000780">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0200190"/>
<obo:IAO_0000111>GenePattern HeatMapViewer data visualization</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">The GenePattern process of generating Heat Maps from clustered data.</obo:IAO_0000115>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<rdfs:label>GenePattern HeatMapViewer data visualization</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000781 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000781">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0200190"/>
<obo:IAO_0000111>GenePattern HierarchicalClusteringViewer data visualization</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">The GenePattern process of generating hierarchical clustering visualization from clustered data.</obo:IAO_0000115>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<rdfs:label>GenePattern HierarchicalClusteringViewer data visualization</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000782 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000782">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000713"/>
<obo:IAO_0000136 rdf:resource="http://purl.obolibrary.org/obo/OBI_0000780"/>
<obo:IAO_0000111>GenePattern module HeatMapViewer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A GenePattern software module which is used to generate a heatmap view of data.</obo:IAO_0000115>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<rdfs:label>GenePattern module HeatMapViewer</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000783 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000783">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000713"/>
<obo:IAO_0000136 rdf:resource="http://purl.obolibrary.org/obo/OBI_0000781"/>
<obo:IAO_0000111>GenePattern module HierarchicalClusteringViewer</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A GenePattern software module which is used to generate a view of data that has been hierarchically clustered.</obo:IAO_0000115>
<obo:IAO_0000117>James Malone</obo:IAO_0000117>
<rdfs:label>GenePattern module HierarchicalClusteringViewer</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000829 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000829">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>Sysmex Corporation, Kobe, Japan</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000119>WEB:http://www.sysmex.com/@2009/08/06</obo:IAO_0000119>
<rdfs:label>Sysmex Corporation, Kobe, Japan</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000850 -->
<owl:Thing rdf:about="http://purl.obolibrary.org/obo/OBI_0000850">
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#NamedIndividual"/>
<obo:IAO_0000111>obsolete_the manufacturer role of Agilent</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_the manufacturer role of Agilent</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Thing>
<!-- http://purl.obolibrary.org/obo/OBI_0000853 -->
<owl:Thing rdf:about="http://purl.obolibrary.org/obo/OBI_0000853">
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#NamedIndividual"/>
<obo:IAO_0000111>obsolete_manufacturer role of Bruker Daltonics</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_manufacturer role of Bruker Daltonics</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Thing>
<!-- http://purl.obolibrary.org/obo/OBI_0000863 -->
<owl:Thing rdf:about="http://purl.obolibrary.org/obo/OBI_0000863">
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#NamedIndividual"/>
<obo:IAO_0000111>obsolete_the manufacturer role of Thermo</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_the manufacturer role of Thermo</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Thing>
<!-- http://purl.obolibrary.org/obo/OBI_0000864 -->
<owl:Thing rdf:about="http://purl.obolibrary.org/obo/OBI_0000864">
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#NamedIndividual"/>
<obo:IAO_0000111>obsolete_the manufacturer role of Li-Cor</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_the manufacturer role of Li-Cor</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Thing>
<!-- http://purl.obolibrary.org/obo/OBI_0000866 -->
<owl:Thing rdf:about="http://purl.obolibrary.org/obo/OBI_0000866">
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#NamedIndividual"/>
<obo:IAO_0000111>obsolete_the manufacturer role of Roche</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_the manufacturer role of Roche</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Thing>
<!-- http://purl.obolibrary.org/obo/OBI_0000878 -->
<owl:Thing rdf:about="http://purl.obolibrary.org/obo/OBI_0000878">
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#NamedIndividual"/>
<obo:IAO_0000111>obsolete_the manufacturer role of Ambion</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_the manufacturer role of Ambion</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Thing>
<!-- http://purl.obolibrary.org/obo/OBI_0000881 -->
<owl:Thing rdf:about="http://purl.obolibrary.org/obo/OBI_0000881">
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#NamedIndividual"/>
<obo:IAO_0000111>obsolete_the manufacturer role of BIO-RAD</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_the manufacturer role of BIO-RAD</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Thing>
<!-- http://purl.obolibrary.org/obo/OBI_0000884 -->
<owl:Thing rdf:about="http://purl.obolibrary.org/obo/OBI_0000884">
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#NamedIndividual"/>
<obo:IAO_0000111>obsolete_the regulator role of the FDA</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_the regulator role of the FDA</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Thing>
<!-- http://purl.obolibrary.org/obo/OBI_0000886 -->
<owl:Thing rdf:about="http://purl.obolibrary.org/obo/OBI_0000886">
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#NamedIndividual"/>
<obo:IAO_0000111>obsolete_the manufacturer role of Illumina</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_the manufacturer role of Illumina</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Thing>
<!-- http://purl.obolibrary.org/obo/OBI_0000887 -->
<owl:Thing rdf:about="http://purl.obolibrary.org/obo/OBI_0000887">
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#NamedIndividual"/>
<obo:IAO_0000111>obsolete_the manufacturer role of Helicos</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_the manufacturer role of Helicos</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Thing>
<!-- http://purl.obolibrary.org/obo/OBI_0000890 -->
<owl:Thing rdf:about="http://purl.obolibrary.org/obo/OBI_0000890">
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#NamedIndividual"/>
<obo:IAO_0000111>obsolete_manufacturer role of Bruker Corporation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_manufacturer role of Bruker Corporation</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Thing>
<!-- http://purl.obolibrary.org/obo/OBI_0000898 -->
<owl:Thing rdf:about="http://purl.obolibrary.org/obo/OBI_0000898">
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#NamedIndividual"/>
<obo:IAO_0000111>obsolete_the manufacturer role of Waters</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_the manufacturer role of Waters</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Thing>
<!-- http://purl.obolibrary.org/obo/OBI_0000900 -->
<owl:Thing rdf:about="http://purl.obolibrary.org/obo/OBI_0000900">
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#NamedIndividual"/>
<obo:IAO_0000111>obsolete_manufacturer role of applied biosystems</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_manufacturer role of applied biosystems</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Thing>
<!-- http://purl.obolibrary.org/obo/OBI_0000901 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000901">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000450"/>
<obo:IAO_0000111>U.S. Food and Drug Administration</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000118>FDA</obo:IAO_0000118>
<rdfs:label>U.S. Food and Drug Administration</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000958 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000958">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000963"/>
<obo:IAO_0000111>right handed</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<rdfs:label>right handed</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000979 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000979">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000963"/>
<obo:IAO_0000111>ambidexterous</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<rdfs:label>ambidexterous</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0000998 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0000998">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000963"/>
<obo:IAO_0000111>left handed</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<rdfs:label>left handed</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0001004 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0001004">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0001000"/>
<obo:IAO_0000111>Edingburgh handedness inventory</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The Edinburgh Handedness Inventory is a set of questions used to assess the dominance of a person's right or left hand in everyday activities.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000117>PERSON:Jessica Turner</obo:IAO_0000117>
<obo:IAO_0000119>PMID:5146491#Oldfield, R.C. (1971). The assessment and analysis of handedness: The Edinburgh inventory. Neuropsychologia, 9, 97-113</obo:IAO_0000119>
<obo:IAO_0000119>WEB:http://www.cse.yorku.ca/course_archive/2006-07/W/4441/EdinburghInventory.html</obo:IAO_0000119>
<rdfs:label>Edingburgh handedness inventory</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0001213 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0001213">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>eBioscience</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000117>Karin Breuer</obo:IAO_0000117>
<obo:IAO_0000119>WEB:http://www.ebioscience.com/@2011/04/11</obo:IAO_0000119>
<rdfs:label>eBioscience</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0001224 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0001224">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>Cytopeia</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000117>Karin Breuer</obo:IAO_0000117>
<obo:IAO_0000119>WEB:http://www.cytopeia.com/@2011/04/11</obo:IAO_0000119>
<rdfs:label>Cytopeia</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0001287 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0001287">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>Exalpha Biological</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000117>Karin Breuer</obo:IAO_0000117>
<obo:IAO_0000119>WEB:http://www.exalpha.com/@2011/04/11</obo:IAO_0000119>
<rdfs:label>Exalpha Biological</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0001312 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0001312">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>Apogee Flow Systems</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000117>Karin Breuer</obo:IAO_0000117>
<obo:IAO_0000119>WEB:http://www.apogeeflow.com/@2011/04/11</obo:IAO_0000119>
<rdfs:label>Apogee Flow Systems</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0001320 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0001320">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>Exbio Antibodies</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000117>Karin Breuer</obo:IAO_0000117>
<obo:IAO_0000119>WEB:http://www.exbio.cz/@2011/04/11</obo:IAO_0000119>
<rdfs:label>Exbio Antibodies</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0001321 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0001321">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>Becton Dickinson (BD Biosciences)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000117>Karin Breuer</obo:IAO_0000117>
<obo:IAO_0000119>WEB:http://www.bdbiosciences.com/@2011/04/11</obo:IAO_0000119>
<rdfs:label>Becton Dickinson (BD Biosciences)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0001338 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0001338">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>Dako Cytomation</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000117>Karin Breuer</obo:IAO_0000117>
<obo:IAO_0000119>WEB:http://www.dakousa.com/@2011/04/11</obo:IAO_0000119>
<rdfs:label>Dako Cytomation</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0001340 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0001340">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>Millipore</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000117>Karin Breuer</obo:IAO_0000117>
<obo:IAO_0000119>WEB:http://www.guavatechnologies.com/@2011/04/11</obo:IAO_0000119>
<rdfs:label>Millipore</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0001347 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0001347">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>Antigenix</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000117>Karin Breuer</obo:IAO_0000117>
<obo:IAO_0000119>WEB:http://www.antigenix.com/@2011/04/11</obo:IAO_0000119>
<rdfs:label>Antigenix</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0001355 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0001355">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>Partec</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000117>Karin Breuer</obo:IAO_0000117>
<obo:IAO_0000119>WEB:http://www.partec.de/@2011/04/11</obo:IAO_0000119>
<rdfs:label>Partec</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0001372 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0001372">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>Beckman Coulter</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000117>Karin Breuer</obo:IAO_0000117>
<obo:IAO_0000119>WEB:http://www.beckmancoulter.com/@2011/04/11</obo:IAO_0000119>
<rdfs:label>Beckman Coulter</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0001375 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0001375">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>Advanced Instruments Inc. (AI Companies)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000117>Karin Breuer</obo:IAO_0000117>
<obo:IAO_0000119>WEB:http://www.aicompanies.com/@2011/04/11</obo:IAO_0000119>
<rdfs:label>Advanced Instruments Inc. (AI Companies)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0001424 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0001424">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>Miltenyi Biotec</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000117>Karin Breuer</obo:IAO_0000117>
<obo:IAO_0000119>WEB:http://www.miltenyibiotec.com/@2011/04/11</obo:IAO_0000119>
<rdfs:label>Miltenyi Biotec</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0001428 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0001428">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>AES Chemunex</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000117>Karin Breuer</obo:IAO_0000117>
<obo:IAO_0000119>WEB:http://www.aeschemunex.com/@2011/04/11</obo:IAO_0000119>
<rdfs:label>AES Chemunex</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0001431 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0001431">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>Bentley Instruments</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000117>Karin Breuer</obo:IAO_0000117>
<obo:IAO_0000119>WEB:http://bentleyinstruments.com/@2011/04/11</obo:IAO_0000119>
<rdfs:label>Bentley Instruments</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0001434 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0001434">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>Invitrogen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000117>Karin Breuer</obo:IAO_0000117>
<obo:IAO_0000119>WEB:http://www.invitrogen.com/@2011/04/11</obo:IAO_0000119>
<rdfs:label>Invitrogen</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0001443 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0001443">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>Luminex</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000117>Karin Breuer</obo:IAO_0000117>
<obo:IAO_0000119>WEB:http://www.luminexcorp.com/@2011/04/11</obo:IAO_0000119>
<rdfs:label>Luminex</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0001458 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0001458">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>CytoBuoy</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000117>Karin Breuer</obo:IAO_0000117>
<obo:IAO_0000119>WEB:http://www.cytobuoy.com/@2011/04/11</obo:IAO_0000119>
<rdfs:label>CytoBuoy</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0001855 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0001855">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>Nimblegen</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An organization that focuses on manufacturing target enrichment probe pools for DNA sequencing.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Jie Zheng</obo:IAO_0000117>
<rdfs:label>Nimblegen</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0001856 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0001856">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>Pacific Biosciences</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An organization that supplies tools for studying the synthesis and regulation of DNA, RNA and protein. It developed a powerful technology platform called single molecule real-time (SMRT) technology which enables real-time analysis of biomolecules with single molecule resolution.</obo:IAO_0000115>
<obo:IAO_0000117>Person: Jie Zheng</obo:IAO_0000117>
<rdfs:label>Pacific Biosciences</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0001860 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0001860">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>NanoString Technologies</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An organization that supplies life science tools for translational research and molecular diagnostics based on a novel digital molecular barcoding technology. The NanoString platform can provide simple, multiplexed digital profiling of single molecules.</obo:IAO_0000115>
<rdfs:label>NanoString Technologies</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002193 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002193">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000245"/>
<obo:IAO_0000111>Thermo Fisher Scientific</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An organization that is an American multinational, biotechnology product development company, created in 2006 by the merger of Thermo Electron and Fisher Scientific.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Thermo_Fisher_Scientific</obo:IAO_0000119>
<rdfs:label>Thermo Fisher Scientific</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002206 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002206">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002205"/>
<obo:IAO_0000111>G1: Well differentiated</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A histologic grade according to AJCC 7th edition indicating that the tumor cells and the organization of the tumor tissue appear close to normal.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>G1</obo:IAO_0000118>
<obo:IAO_0000119>https://www.cancer.gov/about-cancer/diagnosis-staging/prognosis/tumor-grade-fact-sheet</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>G1: Well differentiated</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002207 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002207">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002205"/>
<obo:IAO_0000111>G2: Moderately differentiated</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A histologic grade according to AJCC 7th edition indicating that the tumor cells are moderately differentiated and reflect an intermediate grade.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>G2</obo:IAO_0000118>
<obo:IAO_0000119>https://www.cancer.gov/about-cancer/diagnosis-staging/prognosis/tumor-grade-fact-sheet</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>G2: Moderately differentiated</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002208 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002208">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002205"/>
<obo:IAO_0000111>G3: Poorly differentiated</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A histologic grade according to AJCC 7th edition indicating that the tumor cells are poorly differentiated and do not look like normal cells and tissue.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>G3</obo:IAO_0000118>
<obo:IAO_0000119>https://www.cancer.gov/about-cancer/diagnosis-staging/prognosis/tumor-grade-fact-sheet</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>G3: Poorly differentiated</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002209 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002209">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002205"/>
<obo:IAO_0000111>G4: Undifferentiated</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A histologic grade according to AJCC 7th edition indicating that the tumor cells are undifferentiated and do not look like normal cells and tissue.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>G4</obo:IAO_0000118>
<obo:IAO_0000119>https://www.cancer.gov/about-cancer/diagnosis-staging/prognosis/tumor-grade-fact-sheet</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>G4: Undifferentiated</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002211 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002211">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002210"/>
<obo:IAO_0000111>G1 (Fuhrman)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A histologic grade according to the Fuhrman Nuclear Grading System indicating that nuclei are round, uniform, approximately 10um and that nucleoli are inconspicuous or absent.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Grade 1</obo:IAO_0000118>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>G1 (Fuhrman)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002212 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002212">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002210"/>
<obo:IAO_0000111>G2 (Fuhrman)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A histologic grade according to the Fuhrman Nuclear Grading System indicating that nuclei are slightly irregular, approximately 15um and nucleoli are evident.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Grade 2</obo:IAO_0000118>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>G2 (Fuhrman)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002213 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002213">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002210"/>
<obo:IAO_0000111>G3 (Fuhrman)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A histologic grade according to the Fuhrman Nuclear Grading System indicating that nuclei are very irregular, approximately 20um and nucleoli large and prominent.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Grade 3</obo:IAO_0000118>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>G3 (Fuhrman)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002214 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002214">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002210"/>
<obo:IAO_0000111>G4 (Fuhrman)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A histologic grade according to the Fuhrman Nuclear Grading System indicating that nuclei arei bizarre and multilobulated, 20um or greater and nucleoli are prominent and chromatin clumped.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Grade 4</obo:IAO_0000118>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>G4 (Fuhrman)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002217 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002217">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002216"/>
<obo:IAO_0000111>Low grade ovarian tumor</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A histologic grade for ovarian tumor according to a two-tier grading system indicating that the tumor is low grade.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Low grade</obo:IAO_0000118>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Low grade ovarian tumor</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002218 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002218">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002216"/>
<obo:IAO_0000111>High grade ovarian tumor</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A histologic grade for ovarian tumor according to a two-tier grading system indicating that the tumor is high grade.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>High grade</obo:IAO_0000118>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>High grade ovarian tumor</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002220 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002220">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002219"/>
<obo:IAO_0000111>G1 (WHO)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A histologic grade for ovarian tumor according to the World Health Organization indicating that the tumor is well differentiated.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>G1</obo:IAO_0000118>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>G1 (WHO)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002221 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002221">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002219"/>
<obo:IAO_0000111>G2 (WHO)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A histologic grade for ovarian tumor according to the World Health Organization indicating that the tumor is moderately differentiated.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>G2</obo:IAO_0000118>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>G2 (WHO)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002222 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002222">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002219"/>
<obo:IAO_0000111>G3 (WHO)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A histologic grade for ovarian tumor according to the World Health Organization indicating that the tumor is poorly differentiated.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>G3</obo:IAO_0000118>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>G3 (WHO)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002223 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002223">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002219"/>
<obo:IAO_0000111>G4 (WHO)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A histologic grade for ovarian tumor according to the World Health Organization indicating that the tumor is undifferentiated.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>G4</obo:IAO_0000118>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>G4 (WHO)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002225 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002225">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002224"/>
<obo:IAO_0000111>pT0 (colon)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for colon and rectum according to AJCC 7th edition indicating that there is no evidence of primary tumor.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT0 (colon)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002226 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002226">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002224"/>
<obo:IAO_0000111>pTis (colon)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for colon and rectum according to AJCC 7th edition indicating carcinoma in situ (intraepithelial or invasion of lamina propria).</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pTis (colon)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002227 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002227">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002224"/>
<obo:IAO_0000111>pT1 (colon)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for colon and rectum according to AJCC 7th edition indicating that the tumor invades submucosa.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT1 (colon)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002228 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002228">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002224"/>
<obo:IAO_0000111>pT2 (colon)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for colon and rectum according to AJCC 7th edition indicating that the tumor invades muscularis propria.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT2 (colon)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002229 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002229">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002224"/>
<obo:IAO_0000111>pT3 (colon)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for colon and rectum according to AJCC 7th edition indicating that the tumor invades subserosa or into non-peritionealized pericolic or perirectal tissues.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT3 (colon)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002230 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002230">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002224"/>
<obo:IAO_0000111>pT4a (colon)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for colon and rectum according to AJCC 7th edition indicating that the tumor perforates visceral peritoneum.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT4a (colon)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002231 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002231">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002224"/>
<obo:IAO_0000111>pT4b (colon)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for colon and rectum according to AJCC 7th edition indicating that the tumor directly invades other organs or structures.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT4b (colon)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002233 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002233">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002232"/>
<obo:IAO_0000111>pT0 (lung)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that there is no evidence of primary tumor.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT0 (lung)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002234 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002234">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002232"/>
<obo:IAO_0000111>pTis (lung)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for lung according to AJCC 7th edition indicating carcinoma in situ.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pTis (lung)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002235 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002235">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002232"/>
<obo:IAO_0000111>pT1 (lung)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor is 3 cm or less in greatest dimension, surrounded by lung or visceral pleura without bronchoscopic evidence of invasion more proximal than the lobar bronchus (i.e., not in the main bronchus).</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT1 (lung)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002236 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002236">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002232"/>
<obo:IAO_0000111>pT1a (lung)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor is 2 cm or less in greatest dimension.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT1a (lung)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002237 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002237">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002232"/>
<obo:IAO_0000111>pT1b (lung)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor is more than 2 cm but not more than 3 cm in greatest dimension.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT1b (lung)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002238 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002238">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002232"/>
<obo:IAO_0000111>pT2 (lung)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor is more than 3 cm but not more than 7 cm or the tumor has any of the following features: involves main bronchus, 2 cm or more distal to the carina, invades visceral pleura, associated with atelectasis or obstructive pneumonitis that extends to the hilar region but does not involve the entire lung.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT2 (lung)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002239 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002239">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002232"/>
<obo:IAO_0000111>pT2a (lung)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor is more than 3 cm but not more than 5 cm in greatest dimension.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT2a (lung)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002240 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002240">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002232"/>
<obo:IAO_0000111>pT2b (lung)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor is more than 5 cm but not more than 7 cm in greatest dimension.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT2b (lung)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002241 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002241">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002232"/>
<obo:IAO_0000111>pT3 (lung)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor is more than 7 cm or one that directly invades any of: parietal pleura, chest wall (including superior sulcus tumors), diaphragm, phrenic nerve, mediastinal pleura, parietal pericardiu or the tumor is in the main bronchus less than 2 cm distal to the carina but without involvement of the carina or there is associated atelectasis or obstructive pneumonitis of the entire lung or there is separate tumor nodule(s) in the same lobe as the primary.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT3 (lung)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002242 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002242">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002232"/>
<obo:IAO_0000111>pT4 (lung)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor of any size that invades any of the following: mediastinum, heart, great vessels, trachea, recurrent laryngeal nerve, esophagus, vertebral body, carina or there is separate tumor nodule(s) in a different ipsilateral lobe to that of the primary.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT4 (lung)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002244 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002244">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002243"/>
<obo:IAO_0000111>pT0 (kidney)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that there is no evidence of primary tumor.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT0 (kidney)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002245 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002245">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002243"/>
<obo:IAO_0000111>pT1 (kidney)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor is 7 cm or less in greatest dimension and limited to the kidney.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT1 (kidney)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002246 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002246">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002243"/>
<obo:IAO_0000111>pT1a (kidney)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor is 4 cm or less.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT1a (kidney)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002247 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002247">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002243"/>
<obo:IAO_0000111>pT1b (kidney)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor is more than 4 cm but not more than 7 cm.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT1b (kidney)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002248 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002248">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002243"/>
<obo:IAO_0000111>pT2 (kidney)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor is more than 7 cm in greatest dimension and limited to the kidney.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT2 (kidney)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002249 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002249">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002243"/>
<obo:IAO_0000111>pT2a (kidney)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor is more than 7 cm but not more than 10 cm.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT2a (kidney)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002250 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002250">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002243"/>
<obo:IAO_0000111>pT2b (kidney)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor is more than 10 cm and limited to the kidney.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT2b (kidney)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002251 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002251">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002243"/>
<obo:IAO_0000111>pT3 (kidney)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor extends into major veins or perinephric tissues but not into the ipsilateral adrenal gland and not beyond the Gerota fascia.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT3 (kidney)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002252 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002252">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002243"/>
<obo:IAO_0000111>pT3a (kidney)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor grossly extends into the renal vein or its segmental (muscle containing) branches, or the tumor invades perirenal and/or renal sinus fat (peripelvic) fat but not beyond Gerota fascia.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT3a (kidney)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002253 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002253">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002243"/>
<obo:IAO_0000111>pT3b (kidney)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor grossly extends into vena cava below diaphragm.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT3b (kidney)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002254 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002254">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002243"/>
<obo:IAO_0000111>pT3c (kidney)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor grossly extends into vena cava above the diaphragm or Invades the wall of the vena cava.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT3c (kidney)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002255 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002255">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002243"/>
<obo:IAO_0000111>pT4 (kidney)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor invades beyond Gerota fascia (including contiguous extension into the ipsilateral adrenal gland).</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT4 (kidney)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002257 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002257">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002256"/>
<obo:IAO_0000111>pT0 (ovary)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that there is no evidence of primary tumor.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT0 (ovary)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002258 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002258">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002256"/>
<obo:IAO_0000111>pT1 (ovary)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor is limited to the ovaries (one or both).</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT1 (ovary)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002259 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002259">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002256"/>
<obo:IAO_0000111>pT1a (ovary)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor is limited to one ovary; capsule intact, no tumor on ovarian surface and no malignant cells in ascites or peritoneal washings.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT1a (ovary)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002260 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002260">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002256"/>
<obo:IAO_0000111>pT1b (ovary)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor is limited to both ovaries; capsule intact, no tumor on ovarian surface and no malignant cells in ascites or peritoneal washings.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT1b (ovary)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002261 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002261">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002256"/>
<obo:IAO_0000111>pT1c (ovary)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor is limited to one or both ovaries with capsule ruptured, tumor on ovarian surface, or malignant cells in ascites or peritoneal washings.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT1c (ovary)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002262 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002262">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002256"/>
<obo:IAO_0000111>pT2 (ovary)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor involves one or both ovaries with pelvic extension.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT2 (ovary)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002263 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002263">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002256"/>
<obo:IAO_0000111>pT2a (ovary)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor has extension and/or implants on uterus and/or tube(s) and no malignant cells in ascites or peritoneal washings.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT2a (ovary)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002264 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002264">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002256"/>
<obo:IAO_0000111>pT2b (ovary)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor has extension to other pelvic tissues and no malignant cells in ascites or peritoneal washings.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT2b (ovary)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002265 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002265">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002256"/>
<obo:IAO_0000111>pT2c (ovary)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor has pelvic extension with malignant cells in ascites or peritoneal washings.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT2c (ovary)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002266 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002266">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002256"/>
<obo:IAO_0000111>pT3 (ovary)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor involves one or both ovaries with microscopically confirmed peritoneal metastasis outside the pelvis and/or regional lymph node metastasis.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT3 (ovary)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002267 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002267">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002256"/>
<obo:IAO_0000111>pT3a (ovary)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor has microscopic peritoneal metastasis beyond pelvis.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT3a (ovary)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002268 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002268">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002256"/>
<obo:IAO_0000111>pT3b (ovary)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor has macroscopic peritoneal, metastatasis beyond pelvis, 2 cm or less in greatest dimension.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT3b (ovary)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002269 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002269">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002256"/>
<obo:IAO_0000111>pT3c (ovary)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor has peritoneal metastasis beyond pelvis, more than 2 cm in greatest dimension and/or regional lymph node metastasis.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pT3c (ovary)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002271 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002271">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002270"/>
<obo:IAO_0000111>pN0 (colon)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating no regional lymph node metastsis.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_n/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pN0 (colon)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002272 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002272">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002270"/>
<obo:IAO_0000111>pN1 (colon)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating metastasis in 1-3 regional lymph nodes.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_n/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pN1 (colon)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002273 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002273">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002270"/>
<obo:IAO_0000111>pN1a (colon)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating metastasis in 1 regional lymph node.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_n/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pN1a (colon)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002274 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002274">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002270"/>
<obo:IAO_0000111>pN1b (colon)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating metastasis in 2-3 regional lymph nodes.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_n/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pN1b (colon)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002275 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002275">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002270"/>
<obo:IAO_0000111>pN1c (colon)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating tumor deposit(s), i.e., satellites in the subserosa, or in non-peritonealized pericolic or perirectal soft tissue without regional lymph node metastasis.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_n/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pN1c (colon)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002276 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002276">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002270"/>
<obo:IAO_0000111>pN2 (colon)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating metastasis in 4 or more regional lymph nodes.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_n/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pN2 (colon)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002277 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002277">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002270"/>
<obo:IAO_0000111>pN2a (colon)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating metastasis in 4 to 6 regional lymph nodes.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_n/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pN2a (colon)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002278 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002278">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002270"/>
<obo:IAO_0000111>pN2b (colon)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating metastasis in 7 or more regional lymph nodes.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_n/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pN2b (colon)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002280 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002280">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002279"/>
<obo:IAO_0000111>pN0 (lung)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic lymph node stage for lung according to AJCC 7th edition indicating no regional lymph node metastasis.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_n/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pN0 (lung)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002281 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002281">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002279"/>
<obo:IAO_0000111>pN1 (lung)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic lymph node stage for lung according to AJCC 7th edition indicating metastasis in ipsilateral peribronchial and/or ipsilateral hilar lymph nodes and intrapulmonary nodes, including involvement by direct extension.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_n/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pN1 (lung)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002282 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002282">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002279"/>
<obo:IAO_0000111>pN2 (lung)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic lymph node stage for lung according to AJCC 7th edition indicating metastasis in ipsilateral mediastinal and/or subcarinal lymph node(s).</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_n/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pN2 (lung)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002283 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002283">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002279"/>
<obo:IAO_0000111>pN3 (lung)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic lymph node stage for lung according to AJCC 7th edition indicating metastasis in contralateral mediastinal, contralateral hilar, ipsilateral or contralateral scalene, or supraclavicular lymph node(s).</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_n/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pN3 (lung)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002285 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002285">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002284"/>
<obo:IAO_0000111>pN0 (kidney)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic lymph node stage for kidney according to AJCC 7th edition indicating that there is no regional lymph node metastasis.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_n/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pN0 (kidney)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002286 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002286">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002284"/>
<obo:IAO_0000111>pN1 (kidney)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic lymph node stage for kidney according to AJCC 7th edition indicating that there is regional lymph node metastasis.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_n/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pN1 (kidney)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002288 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002288">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002287"/>
<obo:IAO_0000111>pN0 (ovary)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic lymph node stage for ovary according to AJCC 7th edition indicating that there is no regional lymph node metastasis.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_n/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pN0 (ovary)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002289 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002289">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002287"/>
<obo:IAO_0000111>pN1 (ovary)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic lymph node stage for ovary according to AJCC 7th edition indicating that there is regional lymph node metastasis.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_n/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pN1 (ovary)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002291 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002291">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002290"/>
<obo:IAO_0000111>cM0 (colon)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic distant metastases stage for colon according to AJCC 7th edition indicating that there are no symptoms or signs of distant metastasis.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Cancer_staging#Pathological_M_Categorization_.28cM_and_pM.29</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>cM0 (colon)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002292 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002292">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002290"/>
<obo:IAO_0000111>cM1 (colon)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic distant metastases stage for colon according to AJCC 7th edition indicating that there is clinical evidence of distant metastases by history, physical examination, imaging studies, or invasive procedures, but without microscopic evidence of the presumed distant metastases.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Cancer_staging#Pathological_M_Categorization_.28cM_and_pM.29</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>cM1 (colon)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002293 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002293">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002290"/>
<obo:IAO_0000111>cM1a (colon)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic distant metastases stage for colon according to AJCC 7th edition indicating that metastasis is confined to one organ based on clinical assessment.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_m/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>cM1a (colon)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002294 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002294">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002290"/>
<obo:IAO_0000111>cM1b (colon)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic distant metastases stage for colon according to AJCC 7th edition indicating that metastasis is in more than one organ or the peritoneum based on clinical assessment.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_m/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>cM1b (colon)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002295 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002295">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002290"/>
<obo:IAO_0000111>pM1 (colon)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic distant metastases stage for colon according to AJCC 7th edition indicating that there is microscopic evidence confirming distant metastatic disease.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_m/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pM1 (colon)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002296 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002296">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002290"/>
<obo:IAO_0000111>pM1a (colon)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic distant metastases stage for colon according to AJCC 7th edition indicating that metastasis is confined to one organ and histologically confirmed.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_m/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pM1a (colon)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002297 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002297">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002290"/>
<obo:IAO_0000111>pM1b (colon)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic distant metastases stage for colon according to AJCC 7th edition indicating that metastasis is in more than one organ or the peritoneum and histologically confirmed.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_m/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pM1b (colon)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002299 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002299">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002298"/>
<obo:IAO_0000111>cM0 (lung)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic distant metastases stage for lung according to AJCC 7th edition indicating that there is no distant metastasis.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_m/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>cM0 (lung)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002300 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002300">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002298"/>
<obo:IAO_0000111>cM1 (lung)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic distant metastases stage for lung according to AJCC 7th edition indicating that there are distant metastases based on clinical assessment.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_m/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>cM1 (lung)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002301 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002301">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002298"/>
<obo:IAO_0000111>cM1a (lung)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic distant metastases stage for lung according to AJCC 7th edition indicating that metastasis is based on clinical assessment and a separate tumor nodule(s) in a contralateral lobe; tumor with pleural nodules OR malignant pleural or pericardial effusion.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_m/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>cM1a (lung)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002302 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002302">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002298"/>
<obo:IAO_0000111>cM1b (lung)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic distant metastases stage for lung according to AJCC 7th edition indicating that there is a distant metastases based on clinical assessment.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_m/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>cM1b (lung)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002303 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002303">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002298"/>
<obo:IAO_0000111>pM1 (lung)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic distant metastases stage for lung according to AJCC 7th edition indicating that there is a distant metastases that is histologically confirmed.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_m/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pM1 (lung)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002304 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002304">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002298"/>
<obo:IAO_0000111>pM1a (lung)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic distant metastases stage for lung according to AJCC 7th edition indicating that metastasis is histologically confirmed and a separate tumor nodule(s) in a contralateral lobe; tumor with pleural nodules OR malignant pleural or pericardial effusion.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_m/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pM1a (lung)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002305 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002305">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002298"/>
<obo:IAO_0000111>pM1b (lung)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic distant metastases stage for lung according to AJCC 7th edition indicating that there is a distant metastases that is histologically confirmed and associated with distant lymph nodes or carcinomatosis.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_m/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pM1b (lung)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002307 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002307">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002306"/>
<obo:IAO_0000111>cM0 (kidney)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic distant metastases stage for kidney according to AJCC 7th edition indicating that there is no distant metastasis.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_m/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>cM0 (kidney)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002308 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002308">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002306"/>
<obo:IAO_0000111>cM1 (kidney)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic distant metastases stage for kidney according to AJCC 7th edition indicating that there are distant metastases based on clinical assessment.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_m/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>cM1 (kidney)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002309 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002309">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002306"/>
<obo:IAO_0000111>pM1 (kidney)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic distant metastases stage for kidney according to AJCC 7th edition indicating that there is a distant metastases that is histologically confirmed.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_m/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pM1 (kidney)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002311 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002311">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002310"/>
<obo:IAO_0000111>cM0 (ovary)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic distant metastases stage for ovary according to AJCC 7th edition indicating that there is no distant metastasis.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_m/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>cM0 (ovary)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002312 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002312">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002310"/>
<obo:IAO_0000111>cM1 (ovary)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic distant metastases stage for ovary according to AJCC 7th edition indicating that there is distant metastasis except peritoneal metastasis based on clinical assessment.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_m/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>cM1 (ovary)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002313 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002313">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002310"/>
<obo:IAO_0000111>pM1 (ovary)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A pathologic distant metastases stage for ovary according to AJCC 7th edition indicating that there is distant metastasis except peritoneal metastasis that is histologically confirmed.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_m/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>pM1 (ovary)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002315 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002315">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002314"/>
<obo:IAO_0000111>Occult Carcinoma (AJCC 7th)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A clinical tumor stage group according to AJCC 7th edition indicating a small carcinoma, either asymptomatic or giving rise to metastases without symptoms due to the primary carcinoma.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Occult Carcinoma</obo:IAO_0000118>
<obo:IAO_0000119>http://www.medilexicon.com/dictionary/14371</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Occult Carcinoma (AJCC 7th)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002316 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002316">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002314"/>
<obo:IAO_0000111>Stage 0 (AJCC 7th)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A clinical tumor stage group according to AJCC 7th edition indicating a carcinoma in situ (or melanoma in situ for melanoma of the skin or germ cell neoplasia in situ for testicular germ cell tumors) and generally is considered to have no metastatic potential.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Stage 0</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Cancer_staging</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Stage 0 (AJCC 7th)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002317 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002317">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002314"/>
<obo:IAO_0000111>Stage I (AJCC 7th)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A clinical tumor stage group according to AJCC 7th edition indicating cancers that are smaller or less deeply invasive without regional disease or nodes.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Stage I</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Cancer_staging</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Stage I (AJCC 7th)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002318 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002318">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002314"/>
<obo:IAO_0000111>Stage IIA (AJCC 7th)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A clinical tumor stage group according to AJCC 7th edition indicating cancers with increasing tumor or nodal extent but less than in Stage III and with differing characteristics from IIB and IIC.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Stage IIA</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Cancer_staging</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Stage IIA (AJCC 7th)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002319 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002319">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002314"/>
<obo:IAO_0000111>Stage IIB (AJCC 7th)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A clinical tumor stage group according to AJCC 7th edition indicating cancers with increasing tumor or nodal extent but less than in Stage III and with differing characteristics from IIA and IIC.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Stage IIB</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Cancer_staging</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Stage IIB (AJCC 7th)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002320 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002320">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002314"/>
<obo:IAO_0000111>Stage IIC (AJCC 7th)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A clinical tumor stage group according to AJCC 7th edition indicating cancers with increasing tumor or nodal extent but less than in Stage III and with differing characteristics from IIA and IIB.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Stage IIC</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Cancer_staging</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Stage IIC (AJCC 7th)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002321 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002321">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002314"/>
<obo:IAO_0000111>Stage IIIA (AJCC 7th)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A clinical tumor stage group according to AJCC 7th edition indicating cancers with increasing tumor or nodal extent greater than in Stage II and with differing characteristics from IIIB and IIIC.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Stage IIIA</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Cancer_staging</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Stage IIIA (AJCC 7th)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002322 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002322">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002314"/>
<obo:IAO_0000111>Stage IIIB (AJCC 7th)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A clinical tumor stage group according to AJCC 7th edition indicating cancers with increasing tumor or nodal extent greater than in Stage II and with differing characteristics from IIIA and IIIC.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Stage IIIB</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Cancer_staging</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Stage IIIB (AJCC 7th)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002323 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002323">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002314"/>
<obo:IAO_0000111>Stage IIIC (AJCC 7th)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A clinical tumor stage group according to AJCC 7th edition indicating cancers with increasing tumor or nodal extent greater than in Stage II and with differing characteristics from IIIA and IIIB.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Stage IIIC</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Cancer_staging</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Stage IIIC (AJCC 7th)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002324 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002324">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002314"/>
<obo:IAO_0000111>Stage IVA (AJCC 7th)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A clinical tumor stage group according to AJCC 7th edition indicating cancers in patients who present with distant metastases at diagnosis and with differing characteristics from IVB.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Stage IVA</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Cancer_staging</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Stage IVA (AJCC 7th)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002325 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002325">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002314"/>
<obo:IAO_0000111>Stage IVB (AJCC 7th)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A clinical tumor stage group according to AJCC 7th edition indicating cancers in patients who present with distant metastases at diagnosis and with differing characteristics from IVA.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Stage IVB</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Cancer_staging</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Stage IVB (AJCC 7th)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002327 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002327">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002326"/>
<obo:IAO_0000111>Stage IA (FIGO)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating invasive carcinoma which can be diagnosed only by microscopy, with deepest invasion <5 mm and the largest extension <7 mm.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Stage IA</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Cervical_cancer_staging</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Stage IA (FIGO)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002328 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002328">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002326"/>
<obo:IAO_0000111>Stage IA1 (FIGO)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating measured stromal invasion of <3.0 mm in depth and extension of <7.0 mm.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Stage IA1</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Cervical_cancer_staging</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Stage IA1 (FIGO)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002329 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002329">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002326"/>
<obo:IAO_0000111>Stage IA2 (FIGO)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating measured stromal invasion of >3.0 mm and not >5.0 mm with an extension of not >7.0 mm.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Stage IA2</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Cervical_cancer_staging</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Stage IA2 (FIGO)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002330 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002330">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002326"/>
<obo:IAO_0000111>Stage IB (FIGO)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating clinically visible lesions limited to the cervix uteri or pre-clinical cancers greater than stage IA</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Stage IB</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Cervical_cancer_staging</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Stage IB (FIGO)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002331 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002331">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002326"/>
<obo:IAO_0000111>Stage IB1 (FIGO)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating clinically visible lesion limited to the cervix uteri or pre-clinical cancers greater than stage IA <4.0 cm in greatest dimension.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Stage IB1</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Cervical_cancer_staging</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Stage IB1 (FIGO)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002332 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002332">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002326"/>
<obo:IAO_0000111>Stage IB2 (FIGO)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating clinically visible lesion limited to the cervix uteri or pre-clinical cancers greater than stage IA >4.0 cm in greatest dimension.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Stage IB2</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Cervical_cancer_staging</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Stage IB2 (FIGO)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002333 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002333">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002326"/>
<obo:IAO_0000111>Stage IIA (FIGO)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating cervical carcinoma invades beyond the uterus, but not to the pelvic wall or to the lower third of the vagina without parametrial invasion.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Stage IIA</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Cervical_cancer_staging</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Stage IIA (FIGO)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002334 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002334">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002326"/>
<obo:IAO_0000111>Stage IIA1 (FIGO)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating cervical carcinoma invades beyond the uterus, but not to the pelvic wall or to the lower third of the vagina without parametrial invasion and clinically visible lesion <4.0 cm in greatest dimension.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Stage IIA1</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Cervical_cancer_staging</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Stage IIA1 (FIGO)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002335 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002335">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002326"/>
<obo:IAO_0000111>Stage IIA2 (FIGO)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating cervical carcinoma invades beyond the uterus, but not to the pelvic wall or to the lower third of the vagina without parametrial invasion and clinically visible lesion >4.0 cm in greatest dimension.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Stage IIA2</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Cervical_cancer_staging</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Stage IIA2 (FIGO)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002336 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002336">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002326"/>
<obo:IAO_0000111>Stage IIB (FIGO)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating cervical carcinoma invades beyond the uterus, but not to the pelvic wall or to the lower third of the vagina with obvious parametrial invasion.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Stage IIB</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Cervical_cancer_staging</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Stage IIB (FIGO)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002337 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002337">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002326"/>
<obo:IAO_0000111>Stage IIIA (FIGO)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating tumour involves lower third of the vagina, with no extension to the pelvic wall.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Stage IIIA</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Cervical_cancer_staging</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Stage IIIA (FIGO)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002338 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002338">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002326"/>
<obo:IAO_0000111>Stage IIIB (FIGO)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating extension to the pelvic wall and/or hydronephrosis or non-functioning kidney.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Stage IIIB</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Cervical_cancer_staging</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Stage IIIB (FIGO)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002339 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002339">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002326"/>
<obo:IAO_0000111>Stage IVA (FIGO)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating spread of the growth to adjacent organs.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Stage IVA</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Cervical_cancer_staging</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Stage IVA (FIGO)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002340 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002340">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002326"/>
<obo:IAO_0000111>Stage IVB (FIGO)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating spread to distant organs.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Stage IVB</obo:IAO_0000118>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Cervical_cancer_staging</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Stage IVB (FIGO)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002342 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002342">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002341"/>
<obo:IAO_0000111>Stage 1 (FIGO)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T1, N0, and M0.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Stage 1</obo:IAO_0000118>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Stage 1 (FIGO)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002343 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002343">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002341"/>
<obo:IAO_0000111>Stage 1A (FIGO)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T1a, N0, and M0.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Stage 1A</obo:IAO_0000118>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Stage 1A (FIGO)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002344 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002344">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002341"/>
<obo:IAO_0000111>Stage 1B (FIGO)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T1b, N0, and M0.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Stage 1B</obo:IAO_0000118>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Stage 1B (FIGO)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002345 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002345">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002341"/>
<obo:IAO_0000111>Stage 1C (FIGO)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T1c, N0, and M0.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Stage 1C</obo:IAO_0000118>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Stage 1C (FIGO)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002346 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002346">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002341"/>
<obo:IAO_0000111>Stage 2 (FIGO)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T2, N0, and M0.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Stage 2</obo:IAO_0000118>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Stage 2 (FIGO)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002347 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002347">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002341"/>
<obo:IAO_0000111>Stage 2A (FIGO)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T2a, N0, and M0.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Stage 2A</obo:IAO_0000118>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Stage 2A (FIGO)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002348 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002348">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002341"/>
<obo:IAO_0000111>Stage 2B (FIGO)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T2b, N0, and M0.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Stage 2B</obo:IAO_0000118>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Stage 2B (FIGO)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002349 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002349">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002341"/>
<obo:IAO_0000111>Stage 2C (FIGO)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T2c, N0, and M0.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Stage 2C</obo:IAO_0000118>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Stage 2C (FIGO)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002350 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002350">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002341"/>
<obo:IAO_0000111>Stage 3 (FIGO)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of (T3, N0, and M0) or (T3,3a,3b, NX, and M0).</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Stage 3</obo:IAO_0000118>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Stage 3 (FIGO)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002351 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002351">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002341"/>
<obo:IAO_0000111>Stage 3A (FIGO)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T3a, N0, and M0 .</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Stage 3A</obo:IAO_0000118>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Stage 3A (FIGO)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002352 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002352">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002341"/>
<obo:IAO_0000111>Stage 3B (FIGO)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T3b, N0, and M0 .</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Stage 3B</obo:IAO_0000118>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Stage 3B (FIGO)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002353 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002353">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002341"/>
<obo:IAO_0000111>Stage 3C (FIGO)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of (T3c, N0,X and M0) or (any T, N1 and M0).</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Stage 3C</obo:IAO_0000118>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Stage 3C (FIGO)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002354 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002354">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002341"/>
<obo:IAO_0000111>Stage 4 (FIGO)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of any T, any N, and M1.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Stage 4</obo:IAO_0000118>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Stage 4 (FIGO)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002355 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002355">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002341"/>
<obo:IAO_0000111>Stage Unknown (FIGO)</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of (T0, N0, and M0) or (T1,1a-1c,2,2a-2c, NX, and M0) or (TX, N0,X, M0).</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000118>Stage Unknown</obo:IAO_0000118>
<obo:IAO_0000119>https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>Stage Unknown (FIGO)</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002358 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002358">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002357"/>
<obo:IAO_0000111>3: symptomatic in bed more than 50% of the day but not bed ridden</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An Eastern Cooperative Oncology Group score value specification indicating a patient is symptomatic and in bed for more than 50% of the day but is not bed ridden.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>3: symptomatic in bed more than 50% of the day but not bed ridden</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002359 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002359">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002357"/>
<obo:IAO_0000111>2: symptomatic but in bed less than 50% of the day</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An Eastern Cooperative Oncology Group score value specification indicating a patient is symptomatic but is in bed for less than 50% of the day.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>2: symptomatic but in bed less than 50% of the day</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002360 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002360">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002357"/>
<obo:IAO_0000111>4: bed ridden</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An Eastern Cooperative Oncology Group score value specification indicating a patient is symptomatic and is bed ridden.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>4: bed ridden</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002361 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002361">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002357"/>
<obo:IAO_0000111>0: asymptomatic</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An Eastern Cooperative Oncology Group score value specification indicating a patient is asymptomatic.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>0: asymptomatic</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002362 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002362">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002357"/>
<obo:IAO_0000111>1: symptomatic but fully ambulatory</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An Eastern Cooperative Oncology Group score value specification indicating a patient is symptomatic but is fully ambulatory.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>1: symptomatic but fully ambulatory</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002364 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002364">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002363"/>
<obo:IAO_0000111>100: asymptomatic</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A Karnofsky score vaue specification indicating that a patient is asymptomatic.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>100: asymptomatic</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002365 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002365">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002363"/>
<obo:IAO_0000111>80-90: symptomatic but fully ambulatory</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A Karnofsky score vaue specification indicating that a patient is symptomatic but fully ambulatory.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>80-90: symptomatic but fully ambulatory</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002366 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002366">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002363"/>
<obo:IAO_0000111>60-70: symptomatic but in bed less than 50% of the day</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A Karnofsky score vaue specification indicating that a patient is symptomatic but in bed less than 50% of the day.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>60-70: symptomatic but in bed less than 50% of the day</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002367 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002367">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0002363"/>
<obo:IAO_0000111>40-50: symptomatic, in bed more than 50% of the day, but not bed ridden</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A Karnofsky score vaue specification indicating that a patient is symptomatic, in bed more than 50% of the day, but not bed ridden.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Stoeckert, Helena Ellis</obo:IAO_0000117>
<obo:IAO_0000119>NCI BBRB, OBI</obo:IAO_0000119>
<obo:IAO_0000234>NCI BBRB</obo:IAO_0000234>
<rdfs:label>40-50: symptomatic, in bed more than 50% of the day, but not bed ridden</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002755 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002755">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>Oxford Nanopore Technologies</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An organization that is developing and selling nanopore sequencing products and is based in the UK.</obo:IAO_0000115>
<obo:IAO_0000117>James A. Overton</obo:IAO_0000117>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Oxford_Nanopore_Technologies</obo:IAO_0000119>
<rdfs:label>Oxford Nanopore Technologies</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0002903 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0002903">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>BioGents</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An organization that manufactures mosquito traps and other mosquito control products.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins</obo:IAO_0000117>
<obo:IAO_0000119>WEB:https://eu.biogents.com/about-biogents/</obo:IAO_0000119>
<rdfs:label>BioGents</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0003495 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0003495">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>Abbott</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A manufacturer of rapid point-of-care assay devices.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins ORCID:0000-0001-6595-0902</obo:IAO_0000117>
<obo:IAO_0000119>WEB:https://www.globalpointofcare.abbott/en/about.html</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1456</obo:IAO_0000233>
<rdfs:label>Abbott</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0003496 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0003496">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>J. Mitra</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A manufacturer of in vitro diagnostic assay kits in India.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins ORCID:0000-0001-6595-0902</obo:IAO_0000117>
<obo:IAO_0000119>WEB:https://jmitra.co.in/about-us/</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1456</obo:IAO_0000233>
<rdfs:label>J. Mitra</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OBI_0003497 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OBI_0003497">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
<obo:IAO_0000111>InBios</obo:IAO_0000111>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A manufacturer that specializes in in vitro diagnostic devices designed to test for infectious diseases.</obo:IAO_0000115>
<obo:IAO_0000117>John Judkins ORCID:0000-0001-6595-0902</obo:IAO_0000117>
<obo:IAO_0000119>WEB:https://inbios.com/about/</obo:IAO_0000119>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1456</obo:IAO_0000233>
<rdfs:label>InBios</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OMO_0001000 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OMO_0001000">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000225"/>
<obo:IAO_0000115 xml:lang="en">The term was added to the ontology on the assumption it was in scope, but it turned out later that it was not.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">This obsolesence reason should be used conservatively. Typical valid examples are: un-necessary grouping classes in disease ontologies, a phenotype term added on the assumption it was a disease.</obo:IAO_0000116>
<obo:IAO_0000117 rdf:resource="http://orcid.org/0000-0001-5208-3432"/>
<obo:IAO_0000233>https://github.com/information-artifact-ontology/ontology-metadata/issues/77</obo:IAO_0000233>
<obo:IAO_0000234>https://orcid.org/0000-0001-5208-3432</obo:IAO_0000234>
<rdfs:label>out of scope</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/OMO_0001002 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OMO_0001002">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000225"/>
<obo:IAO_0000115 xml:lang="en">The term was added to the ontology on the assumption it was a valid domain entity, but it turns out the entity does not exist in reality.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">This obsolesence reason should be used conservatively. For example: Obsoleting class that describes a breed of cow based on a record in an existing database, that was later retracted as faulty (breed does not exist). Do not use this term to obsolete a historic concept (that was once valid, but not anymore). </obo:IAO_0000116>
<obo:IAO_0000117 rdf:resource="http://orcid.org/0000-0002-4142-7153"/>
<obo:IAO_0000233>https://github.com/information-artifact-ontology/ontology-metadata/issues/136</obo:IAO_0000233>
<obo:IAO_0000234>https://orcid.org/0000-0002-4142-7153</obo:IAO_0000234>
<rdfs:label>domain entity does not exist</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000008 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000008">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000001"/>
<obo:IAO_0000111>meter</obo:IAO_0000111>
<obo:IAO_0000115>A length unit which is equal to the length of the path traveled by light in vacuum during a time interval of 1/299 792 458 of a second.</obo:IAO_0000115>
<obo:IAO_0000118>m</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>meter</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000009 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000009">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000002"/>
<obo:IAO_0000111>kilogram</obo:IAO_0000111>
<obo:IAO_0000115>A mass unit which is equal to the mass of the International Prototype Kilogram kept by the BIPM at Svres, France.</obo:IAO_0000115>
<obo:IAO_0000118>kg</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>kilogram</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000010 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000010">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000003"/>
<obo:IAO_0000111>second</obo:IAO_0000111>
<obo:IAO_0000115>A time unit which is equal to the duration of 9 192 631 770 periods of the radiation corresponding to the transition between the two hyperfine levels of the ground state of the caesium 133 atom.</obo:IAO_0000115>
<obo:IAO_0000118>s</obo:IAO_0000118>
<obo:IAO_0000118>sec</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>second</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000015 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000015">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000001"/>
<obo:IAO_0000111>centimeter</obo:IAO_0000111>
<obo:IAO_0000115>A length unit which is equal to one hundredth of a meter or 10^[-2] m.</obo:IAO_0000115>
<obo:IAO_0000118>cm</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>centimeter</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000016 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000016">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000001"/>
<obo:IAO_0000111>millimeter</obo:IAO_0000111>
<obo:IAO_0000115>A length unit which is equal to one thousandth of a meter or 10^[-3] m.</obo:IAO_0000115>
<obo:IAO_0000118>mm</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>millimeter</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000017 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000017">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000001"/>
<obo:IAO_0000111>micrometer</obo:IAO_0000111>
<obo:IAO_0000115>A length unit which is equal to one millionth of a meter or 10^[-6] m.</obo:IAO_0000115>
<obo:IAO_0000118>um</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>micrometer</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000018 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000018">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000001"/>
<obo:IAO_0000111>nanometer</obo:IAO_0000111>
<obo:IAO_0000115>A length unit which is equal to one thousandth of one millionth of a meter or 10^[-9] m.</obo:IAO_0000115>
<obo:IAO_0000118>nm</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>nanometer</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000019 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000019">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000001"/>
<obo:IAO_0000111>angstrom</obo:IAO_0000111>
<obo:IAO_0000115>A length unit which is equal to 10 [-10] m.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>angstrom</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000021 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000021">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000002"/>
<obo:IAO_0000111>gram</obo:IAO_0000111>
<obo:IAO_0000115>A mass unit which is equal to one thousandth of a kilogram or 10^[-3] kg.</obo:IAO_0000115>
<obo:IAO_0000118>g</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>gram</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000022 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000022">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000002"/>
<obo:IAO_0000111>milligram</obo:IAO_0000111>
<obo:IAO_0000115>A mass unit which is equal to one thousandth of a gram or 10^[-3] g.</obo:IAO_0000115>
<obo:IAO_0000118>mg</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>milligram</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000023 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000023">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000002"/>
<obo:IAO_0000111>microgram</obo:IAO_0000111>
<obo:IAO_0000115>A mass unit which is equal to one millionth of a gram or 10^[-6] g.</obo:IAO_0000115>
<obo:IAO_0000118>ug</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>microgram</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000024 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000024">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000002"/>
<obo:IAO_0000111>nanogram</obo:IAO_0000111>
<obo:IAO_0000115>A mass unit which is equal to one thousandth of one millionth of a gram or 10^[-9] g.</obo:IAO_0000115>
<obo:IAO_0000118>ng</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>nanogram</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000025 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000025">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000002"/>
<obo:IAO_0000111>picogram</obo:IAO_0000111>
<obo:IAO_0000115>A mass unit which is equal to 10^[-12] g.</obo:IAO_0000115>
<obo:IAO_0000118>pg</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>picogram</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000027 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000027">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000005"/>
<obo:IAO_0000111>degree Celsius</obo:IAO_0000111>
<obo:IAO_0000115>A temperature unit which is equal to one kelvin degree. However, they have their zeros at different points. The centigrade scale has its zero at 273.15 K.</obo:IAO_0000115>
<obo:IAO_0000118>C</obo:IAO_0000118>
<obo:IAO_0000118>degree C</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>degree Celsius</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000031 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000031">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000003"/>
<obo:IAO_0000111>minute</obo:IAO_0000111>
<obo:IAO_0000115>A time unit which is equal to 60 seconds.</obo:IAO_0000115>
<obo:IAO_0000118>min</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>minute</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000032 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000032">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000003"/>
<obo:IAO_0000111>hour</obo:IAO_0000111>
<obo:IAO_0000115>A time unit which is equal to 3600 seconds or 60 minutes.</obo:IAO_0000115>
<obo:IAO_0000118>h</obo:IAO_0000118>
<obo:IAO_0000118>hr</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>hour</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000033 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000033">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000003"/>
<obo:IAO_0000111>day</obo:IAO_0000111>
<obo:IAO_0000115>A time unit which is equal to 24 hours.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>day</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000034 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000034">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000003"/>
<obo:IAO_0000111>week</obo:IAO_0000111>
<obo:IAO_0000115>A time unit which is equal to 7 days.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>week</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000035 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000035">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000003"/>
<obo:IAO_0000111>month</obo:IAO_0000111>
<obo:IAO_0000115>A time unit which is approximately equal to the length of time of one of cycle of the moon's phases which in science is taken to be equal to 30 days.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>month</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000036 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000036">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000003"/>
<obo:IAO_0000111>year</obo:IAO_0000111>
<obo:IAO_0000115>A time unit which is equal to 12 months which is science is taken to be equal to 365.25 days.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>year</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000039 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000039">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000006"/>
<obo:IAO_0000111>micromole</obo:IAO_0000111>
<obo:IAO_0000115>A substance unit equal to a millionth of a mol or 10^[-6] mol.</obo:IAO_0000115>
<obo:IAO_0000118>umol</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>micromole</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000041 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000041">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000006"/>
<obo:IAO_0000111>nanomole</obo:IAO_0000111>
<obo:IAO_0000115>A substance unit equal to one thousandth of one millionth of a mole or 10^[-9] mol.</obo:IAO_0000115>
<obo:IAO_0000118>nmol</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>nanomole</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000042 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000042">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000006"/>
<obo:IAO_0000111>picomole</obo:IAO_0000111>
<obo:IAO_0000115>A substance unit equal to 10^[-12] mol.</obo:IAO_0000115>
<obo:IAO_0000118>pmol</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>picomole</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000062 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000062">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000051"/>
<obo:IAO_0000111>molar</obo:IAO_0000111>
<obo:IAO_0000115>A unit of concentration which expresses a concentration of 1 mole of solute per liter of solution (mol/L).</obo:IAO_0000115>
<obo:IAO_0000118>M</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>molar</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000063 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000063">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000051"/>
<obo:IAO_0000111>millimolar</obo:IAO_0000111>
<obo:IAO_0000115>A unit of molarity which is equal to one thousandth of a molar or 10^[-3] M.</obo:IAO_0000115>
<obo:IAO_0000118>mM</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>millimolar</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000064 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000064">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000051"/>
<obo:IAO_0000111>micromolar</obo:IAO_0000111>
<obo:IAO_0000115>A unit of molarity which is equal to one millionth of a molar or 10^[-6] M.</obo:IAO_0000115>
<obo:IAO_0000118>uM</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>micromolar</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000065 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000065">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000051"/>
<obo:IAO_0000111>nanomolar</obo:IAO_0000111>
<obo:IAO_0000115>A unit of molarity which is equal to one thousandth of one millionth of a molar or 10^[-9] M.</obo:IAO_0000115>
<obo:IAO_0000118>nM</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>nanomolar</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000066 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000066">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000051"/>
<obo:IAO_0000111>picomolar</obo:IAO_0000111>
<obo:IAO_0000115>A unit of molarity which is equal to 10^[-12] M.</obo:IAO_0000115>
<obo:IAO_0000118>pM</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>picomolar</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000097 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000097">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000095"/>
<obo:IAO_0000111>cubic centimeter</obo:IAO_0000111>
<obo:IAO_0000115>A volume unit which is equal to one millionth of a cubic meter or 10^[-9] m^[3], or to 1 ml.</obo:IAO_0000115>
<obo:IAO_0000118>cc</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>cubic centimeter</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000098 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000098">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000095"/>
<obo:IAO_0000111>milliliter</obo:IAO_0000111>
<obo:IAO_0000115>A volume unit which is equal to one thousandth of a liter or 10^[-3] L, or to 1 cubic centimeter.</obo:IAO_0000115>
<obo:IAO_0000118>ml</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>milliliter</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000099 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000099">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000095"/>
<obo:IAO_0000111>liter</obo:IAO_0000111>
<obo:IAO_0000115>A volume unit which is equal to one thousandth of a cubic meter or 10^[-3] m^[3], or to 1 decimeter.</obo:IAO_0000115>
<obo:IAO_0000118>L</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>liter</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000100 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000100">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000095"/>
<obo:IAO_0000111>cubic decimeter</obo:IAO_0000111>
<obo:IAO_0000115>A volume unit which is equal to one thousand of a cubic meter or 10^[-3] m^[3], or to 1 L.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>cubic decimeter</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000101 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000101">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000095"/>
<obo:IAO_0000111>microliter</obo:IAO_0000111>
<obo:IAO_0000115>A volume unit which is equal to one millionth of a liter or 10^[-6] L.</obo:IAO_0000115>
<obo:IAO_0000118>ul</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>microliter</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000102 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000102">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000095"/>
<obo:IAO_0000111>nanoliter</obo:IAO_0000111>
<obo:IAO_0000115>A volume unit which is equal to one thousandth of one millionth of a liter or 10^[-9] L.</obo:IAO_0000115>
<obo:IAO_0000118>nl</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>nanoliter</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000103 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000103">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000095"/>
<obo:IAO_0000111>picoliter</obo:IAO_0000111>
<obo:IAO_0000115>A volume unit which is equal to 10^[-12] L.</obo:IAO_0000115>
<obo:IAO_0000118>pl</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>picoliter</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000106 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000106">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000105"/>
<obo:IAO_0000111>hertz</obo:IAO_0000111>
<obo:IAO_0000115>A frequency unit which is equal to 1 complete cycle of a recurring phenomenon in 1 second.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>hertz</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000163 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000163">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000051"/>
<obo:IAO_0000111>mass percentage</obo:IAO_0000111>
<obo:IAO_0000115>A dimensionless concentration unit which denotes the mass of a substance in a mixture as a percentage of the mass of the entire mixture.</obo:IAO_0000115>
<obo:IAO_0000118>% w/w</obo:IAO_0000118>
<obo:IAO_0000118>percent weight pr weight</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>mass percentage</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000164 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000164">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000051"/>
<obo:IAO_0000111>mass volume percentage</obo:IAO_0000111>
<obo:IAO_0000115>A dimensionless concentration unit which denotes the mass of the substance in a mixture as a percentage of the volume of the entire mixture.</obo:IAO_0000115>
<obo:IAO_0000118>% w/v</obo:IAO_0000118>
<obo:IAO_0000118>percent vol per vol</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>mass volume percentage</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000165 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000165">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000051"/>
<obo:IAO_0000111>volume percentage</obo:IAO_0000111>
<obo:IAO_0000115>A dimensionless concentration unit which denotes the volume of the solute in mL per 100 mL of the resulting solution.</obo:IAO_0000115>
<obo:IAO_0000118>% v/v</obo:IAO_0000118>
<obo:IAO_0000118>percent vol per vol</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>volume percentage</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000175 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000175">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000051"/>
<obo:IAO_0000111>gram per liter</obo:IAO_0000111>
<obo:IAO_0000115>A mass unit density which is equal to mass of an object in grams divided by the volume in liters.</obo:IAO_0000115>
<obo:IAO_0000118>g per L</obo:IAO_0000118>
<obo:IAO_0000118>g/L</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>gram per liter</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000176 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000176">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000051"/>
<obo:IAO_0000111>milligram per milliliter</obo:IAO_0000111>
<obo:IAO_0000115>A mass unit density which is equal to mass of an object in milligrams divided by the volume in milliliters.</obo:IAO_0000115>
<obo:IAO_0000118>mg per ml</obo:IAO_0000118>
<obo:IAO_0000118>mg/ml</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>milligram per milliliter</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000195 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000195">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000005"/>
<obo:IAO_0000111>degree Fahrenheit</obo:IAO_0000111>
<obo:IAO_0000115>A temperature unit which is equal to 5/9ths of a kelvin. Negative 40 degrees Fahrenheit is equal to negative 40 degrees Celsius.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>degree Fahrenheit</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000196 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000196">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000051"/>
<obo:IAO_0000111>pH</obo:IAO_0000111>
<obo:IAO_0000115>A dimensionless concentration notation which denotes the acidity of a solution in terms of activity of hydrogen ions (H+).</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>pH</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000207 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000207">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000051"/>
<obo:IAO_0000111>milliliter per liter</obo:IAO_0000111>
<obo:IAO_0000115>A volume per unit volume unit which is equal to one millionth of a liter of solute in one liter of solution.</obo:IAO_0000115>
<obo:IAO_0000118>ml per L</obo:IAO_0000118>
<obo:IAO_0000118>ml/l</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>milliliter per liter</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000208 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000208">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000051"/>
<obo:IAO_0000111>gram per deciliter</obo:IAO_0000111>
<obo:IAO_0000115>A mass density unit which is equal to mass of an object in grams divided by the volume in deciliters.</obo:IAO_0000115>
<obo:IAO_0000118>g/dl</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>gram per deciliter</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000212 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000212">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000051"/>
<obo:IAO_0000111>colony forming unit per volume</obo:IAO_0000111>
<obo:IAO_0000115>A concentration unit which a measure of viable bacterial numbers in a given volume.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>colony forming unit per volume</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000271 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000271">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000270"/>
<obo:IAO_0000111>microliters per minute</obo:IAO_0000111>
<obo:IAO_0000115>A volumetric flow rate unit which is equal to one microliter volume through a given surface in one minute.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>microliters per minute</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000281 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000281">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000280"/>
<obo:IAO_0000111>count per nanomolar second</obo:IAO_0000111>
<obo:IAO_0000115>A rate unit which is equal to one over one nanomolar second.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>count per nanomolar second</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000282 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000282">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000280"/>
<obo:IAO_0000111>count per molar second</obo:IAO_0000111>
<obo:IAO_0000115>A rate unit which is equal to one over one molar second.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>count per molar second</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000284 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000284">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000280"/>
<obo:IAO_0000111>count per nanomolar</obo:IAO_0000111>
<obo:IAO_0000115>A rate unit which is equal to one over one nanomolar.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>count per nanomolar</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000285 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000285">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000280"/>
<obo:IAO_0000111>count per molar</obo:IAO_0000111>
<obo:IAO_0000115>A rate unit which is equal to one over one molar.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>count per molar</rdfs:label>
</owl:NamedIndividual>
<!-- http://purl.obolibrary.org/obo/UO_0000301 -->
<owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/UO_0000301">
<rdf:type rdf:resource="http://purl.obolibrary.org/obo/UO_0000051"/>
<obo:IAO_0000111>microgram per liter</obo:IAO_0000111>
<obo:IAO_0000115>A mass unit density which is equal to mass of an object in micrograms divided by the volume in liters.</obo:IAO_0000115>
<obo:IAO_0000118>ng/ml</obo:IAO_0000118>
<obo:IAO_0000118>ug/L</obo:IAO_0000118>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uo.owl"/>
<rdfs:label>microgram per liter</rdfs:label>
</owl:NamedIndividual>
<rdf:Description>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
</rdf:Description>
<rdf:Description>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
</rdf:Description>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Annotations
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<rdf:Description rdf:about="http://example.com/bfo-spec-label">
<obo:IAO_0000119>Person:Alan Ruttenberg</obo:IAO_0000119>
</rdf:Description>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000134">
<obo:IAO_0000600 xml:lang="en">To say that each spatiotemporal region s temporally_projects_onto some temporal region t is to say that t is the temporal extension of s. (axiom label in BFO2 Reference: [080-003])</obo:IAO_0000600>
<obo:IAO_0000600 xml:lang="en">To say that spatiotemporal region s spatially_projects_onto spatial region r at t is to say that r is the spatial extent of s at t. (axiom label in BFO2 Reference: [081-003])</obo:IAO_0000600>
</rdf:Description>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000134"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
<owl:annotatedTarget xml:lang="en">To say that each spatiotemporal region s temporally_projects_onto some temporal region t is to say that t is the temporal extension of s. (axiom label in BFO2 Reference: [080-003])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/080-003"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000134"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
<owl:annotatedTarget xml:lang="en">To say that spatiotemporal region s spatially_projects_onto spatial region r at t is to say that r is the spatial extent of s at t. (axiom label in BFO2 Reference: [081-003])</owl:annotatedTarget>
<obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/081-003"/>
</owl:Axiom>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GAZ_00000448">
<obo:IAO_0000111>geographic location</obo:IAO_0000111>
<obo:IAO_0000115>A reference to a place on the Earth, by its name or by its geographical location.</obo:IAO_0000115>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/gaz.owl"/>
<rdfs:label>geographic location</rdfs:label>
</rdf:Description>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// General axioms
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#AllDisjointClasses"/>
<owl:members rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000004"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000020"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000031"/>
</owl:members>
</rdf:Description>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#AllDisjointClasses"/>
<owl:members rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000006"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000029"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000140"/>
</owl:members>
</rdf:Description>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#AllDisjointClasses"/>
<owl:members rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000008"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000011"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000015"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000035"/>
</owl:members>
</rdf:Description>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#AllDisjointClasses"/>
<owl:members rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000009"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000018"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000026"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000028"/>
</owl:members>
</rdf:Description>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#AllDisjointClasses"/>
<owl:members rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000142"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000146"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000147"/>
</owl:members>
</rdf:Description>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#AllDifferent"/>
<owl:distinctMembers rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000120"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000121"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000122"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000123"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000124"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000125"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000423"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000428"/>
</owl:distinctMembers>
</rdf:Description>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#AllDifferent"/>
<owl:distinctMembers rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000226"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000227"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000228"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000229"/>
</owl:distinctMembers>
</rdf:Description>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Rules
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<rdf:Description rdf:about="urn:swrl#e">
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#Variable"/>
</rdf:Description>
<rdf:Description rdf:about="urn:swrl#d">
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#Variable"/>
</rdf:Description>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#Imp"/>
<swrl:body>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0000053"/>
<swrl:argument1 rdf:resource="urn:swrl#e"/>
<swrl:argument2 rdf:resource="urn:swrl#d"/>
</rdf:Description>
</rdf:first>
<rdf:rest>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#ClassAtom"/>
<swrl:classPredicate rdf:resource="http://purl.obolibrary.org/obo/BFO_0000016"/>
<swrl:argument1 rdf:resource="urn:swrl#d"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</rdf:rest>
</rdf:Description>
</swrl:body>
<swrl:head>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0000091"/>
<swrl:argument1 rdf:resource="urn:swrl#e"/>
<swrl:argument2 rdf:resource="urn:swrl#d"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</swrl:head>
</rdf:Description>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#Imp"/>
<swrl:body>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0000053"/>
<swrl:argument1 rdf:resource="urn:swrl#e"/>
<swrl:argument2 rdf:resource="urn:swrl#d"/>
</rdf:Description>
</rdf:first>
<rdf:rest>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#ClassAtom"/>
<swrl:classPredicate rdf:resource="http://purl.obolibrary.org/obo/BFO_0000019"/>
<swrl:argument1 rdf:resource="urn:swrl#d"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</rdf:rest>
</rdf:Description>
</swrl:body>
<swrl:head>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0000086"/>
<swrl:argument1 rdf:resource="urn:swrl#e"/>
<swrl:argument2 rdf:resource="urn:swrl#d"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</swrl:head>
</rdf:Description>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#Imp"/>
<swrl:body>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0000053"/>
<swrl:argument1 rdf:resource="urn:swrl#e"/>
<swrl:argument2 rdf:resource="urn:swrl#d"/>
</rdf:Description>
</rdf:first>
<rdf:rest>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#ClassAtom"/>
<swrl:classPredicate rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<swrl:argument1 rdf:resource="urn:swrl#d"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</rdf:rest>
</rdf:Description>
</swrl:body>
<swrl:head>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<swrl:argument1 rdf:resource="urn:swrl#e"/>
<swrl:argument2 rdf:resource="urn:swrl#d"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</swrl:head>
</rdf:Description>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#Imp"/>
<swrl:body>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0000053"/>
<swrl:argument1 rdf:resource="urn:swrl#e"/>
<swrl:argument2 rdf:resource="urn:swrl#d"/>
</rdf:Description>
</rdf:first>
<rdf:rest>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#ClassAtom"/>
<swrl:classPredicate rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
<swrl:argument1 rdf:resource="urn:swrl#d"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</rdf:rest>
</rdf:Description>
</swrl:body>
<swrl:head>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
<swrl:argument1 rdf:resource="urn:swrl#e"/>
<swrl:argument2 rdf:resource="urn:swrl#d"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</swrl:head>
</rdf:Description>
</rdf:RDF>
<!-- Generated by the OWL API (version 4.5.25) https://github.com/owlcs/owlapi -->