format-version: 1.2
data-version: releases/2024-02-09/symp.obo
date: 09:02:2024 15:40
saved-by: lschriml
default-namespace: symptoms
ontology: symp
property_value: http://purl.org/dc/elements/1.1/description "The Symptom Ontology has been developed as a standardized ontology for symptoms of human diseases." xsd:string
property_value: http://purl.org/dc/elements/1.1/title "Symptom Ontology" xsd:string
property_value: http://purl.org/dc/terms/license https://creativecommons.org/publicdomain/zero/1.0/
property_value: IAO:0000700 SYMP:0000462
property_value: owl:versionInfo "2024-02-09" xsd:string

[Term]
id: SYMP:0000000
name: cellulitis
def: "Cellulitis is a musculoskeletal system symptom characterized as a diffuse and especially subcutaneous inflammation of connective tissue." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=cellulitis]
comment: doid/symp duplicate
is_a: SYMP:0000891 ! musculoskeletal system symptom

[Term]
id: SYMP:0000001
name: abdominal cramp
synonym: "stomach cramp" EXACT []
is_a: SYMP:0000461 ! abdominal symptom

[Term]
id: SYMP:0000002
name: abdominal distention
is_a: SYMP:0000461 ! abdominal symptom

[Term]
id: SYMP:0000003
name: obsolete acute enteritis in newborns
is_obsolete: true

[Term]
id: SYMP:0000004
name: obsolete arrested moulting
is_obsolete: true

[Term]
id: SYMP:0000005
name: ataxia
def: "A neurological and physiological symptom that is characterized by an inability to coordinate voluntary muscular movements that is symptomatic of some nervous disorders." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=ataxia]
synonym: "uncoordination" EXACT []
is_a: SYMP:0000410 ! neurological and physiological symptom

[Term]
id: SYMP:0000006
name: backache
def: "A pain that is characterized by occurring in the lower back." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=backache]
synonym: "back pain" EXACT []
is_a: SYMP:0000099 ! pain

[Term]
id: SYMP:0000007
name: bleeding
def: "A general symptom that is characterized as an act, instance, or result of being bled or the process by which something is bled: as a the escape of blood from vessels." [url:http\://www.merriam-webster.com/medlineplus/bleeding]
is_a: SYMP:0000567 ! general symptom

[Term]
id: SYMP:0000008
name: blindness
comment: doid/symp duplicate
is_a: SYMP:0000320 ! vision symptom

[Term]
id: SYMP:0000009
name: blister
def: "A skin and integumentary tissue symptom that is characterized by a fluid-filled elevation of the epidermis." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=blister]
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000010
name: obsolete bloody diarrhea
is_obsolete: true

[Term]
id: SYMP:0000011
name: obsolete bloody exudate
is_obsolete: true

[Term]
id: SYMP:0000012
name: blurred vision
def: "A vision symptom that is characterized by a decreased clarity or sharpness in vision, which can be caused by eye conditions myopia or hyperopia." []
is_a: SYMP:0000628 ! vision distortion

[Term]
id: SYMP:0000013
name: obsolete capillary leakage
is_obsolete: true

[Term]
id: SYMP:0000014
name: obsolete cardiomyocyte destruction
is_obsolete: true

[Term]
id: SYMP:0000015
name: giddiness
is_a: SYMP:0000567 ! general symptom

[Term]
id: SYMP:0000016
name: confusion
def: "A balance symptom that is characterized by a disturbance of consciousness characterized by inability to engage in orderly thought or by lack of power to distinguish, choose, or act decisively." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=confusion]
is_a: SYMP:0020045 ! balance symptom

[Term]
id: SYMP:0000017
name: crinkle
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000018
name: darkening of skin
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000019
name: deafness
is_a: SYMP:0000392 ! ear symptom

[Term]
id: SYMP:0000020
name: dehydration
def: "A nutrition, metabolism, and development symptom that is characterized by an abnormal depletion of body fluids." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=dehydration]
is_a: SYMP:0000473 ! nutrition, metabolism, and development symptom

[Term]
id: SYMP:0000021
name: delirium
def: "A neurological and physiological symptom that is characterized by a mental disturbance characterized by confusion, disordered speech, and hallucinations." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=delirium]
is_a: SYMP:0000410 ! neurological and physiological symptom

[Term]
id: SYMP:0000022
name: depression
def: "A neurological and physiological symptom that is characterized by a chronic feeling of emptiness, sadness, or inability to feel pleasure that may appear to happen for no clear reason.  Additionally one may experience feelings of hopelessness, pessimism, irritability, frustration, or restlessness, guilt, worthlessness and thoughts of death or suicide." [url:https\://www.medicalnewstoday.com/articles/8933, url:https\://www.nimh.nih.gov/health/topics/depression]
xref: MESH:D003863
is_a: SYMP:0000410 ! neurological and physiological symptom

[Term]
id: SYMP:0000023
name: disorientation
def: "A confusion that is characterized by an usually transient state of confusion especially as to time, place, or identity; often as a result of disease or drugs." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=disorientation]
is_a: SYMP:0000016 ! confusion

[Term]
id: SYMP:0000024
name: drowsiness
def: "A neurological and physiological symptom that is characterized by a feeling of being more sleepy than normal during the day. People who are drowsy may fall asleep in when they do not want to or at times which can lead to safety concerns." [url:https\://medlineplus.gov/ency/article/003208.htm]
synonym: "drowsy" EXACT []
synonym: "somnolence" EXACT []
is_a: SYMP:0000410 ! neurological and physiological symptom

[Term]
id: SYMP:0000025
name: dry cough
def: "A cough that is characterized by a lack of accompanied phlegm production." []
synonym: "nonproductive cough" EXACT [url:https\://www.healthline.com/health/dry-cough]
is_a: SYMP:0000614 ! cough

[Term]
id: SYMP:0000026
name: obsolete epidermal proliferation
is_obsolete: true

[Term]
id: SYMP:0000027
name: obsolete excess mucus in bronchi
is_obsolete: true

[Term]
id: SYMP:0000028
name: obsolete exophthalmia
synonym: "abnormal protrusion of the eyeball" EXACT []
is_obsolete: true

[Term]
id: SYMP:0000029
name: obsolete feather loss
is_obsolete: true

[Term]
id: SYMP:0000030
name: paralysis
def: "A nervous system symptom that is characterized by a complete or partial loss of function especially when involving the power of motion or of sensation in any part of the body." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=paralysis]
is_a: SYMP:0000480 ! nervous system symptom

[Term]
id: SYMP:0000031
name: obsolete flaccid limb paralysis
is_obsolete: true

[Term]
id: SYMP:0000032
name: flaccidity
is_a: SYMP:0000567 ! general symptom

[Term]
id: SYMP:0000033
name: flat keratotic capsule
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000034
name: obsolete fluid in pericardial sac
is_obsolete: true

[Term]
id: SYMP:0000035
name: obsolete fragile bones
is_obsolete: true

[Term]
id: SYMP:0000036
name: hemorrhagic gastroenteritis
synonym: "haemorrhagic gastroenteritis" EXACT []
is_a: SYMP:0019159 ! gastroenteritis

[Term]
id: SYMP:0000037
name: obsolete catarrhal enteritis
is_obsolete: true

[Term]
id: SYMP:0000038
name: dyspneic enteritis
def: "A respiratory system and chest symptom that is characterized by being short or breath or out of air (dyspnea), with inflammation of the small intestine (enteritis)." [url:https\://medlineplus.gov/ency/article/001149.htm, url:https\://www.cancer.gov/publications/dictionaries/cancer-terms/def/dyspnea]
is_a: SYMP:0000514 ! respiratory system and chest symptom

[Term]
id: SYMP:0000039
name: enteritis
def: "Enteritis is a digestive system symptom involving the inflammation of the small intestines and especially of the human ileum." [url:http\://en.wikipedia.org/wiki/Enteritis, url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=enteritis]
is_a: SYMP:0000459 ! digestive system symptom

[Term]
id: SYMP:0000040
name: hematuria
def: "A urinary system symptom that is characterized by the presence of blood or blood cells in the urine." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=hematuria]
is_a: SYMP:0000486 ! urinary system symptom

[Term]
id: SYMP:0000041
name: hemorrhage
def: "A cardiovascular system symptom that is characterized by an acute loss of blood from a damaged blood vessel." [url:https\://www.ncbi.nlm.nih.gov/books/NBK542273/]
is_a: SYMP:0000528 ! cardiovascular system symptom

[Term]
id: SYMP:0000042
name: obsolete hemorrhagic enteritis
is_obsolete: true

[Term]
id: SYMP:0000043
name: obsolete hemorrhagic meningitis
is_obsolete: true

[Term]
id: SYMP:0000044
name: obsolete hemorrhagic thoracic lymphadenitis
is_obsolete: true

[Term]
id: SYMP:0000045
name: hepatic necrosis
is_a: SYMP:0000180 ! liver symptom

[Term]
id: SYMP:0000046
name: hepatitis
comment: doid/symp duplicate
is_a: SYMP:0000180 ! liver symptom

[Term]
id: SYMP:0000047
name: hepatosplenomegaly
is_a: SYMP:0000158 ! spleen symptom
is_a: SYMP:0000180 ! liver symptom

[Term]
id: SYMP:0000048
name: obsolete high fever
is_obsolete: true

[Term]
id: SYMP:0000049
name: obsolete hind limb paralysis
synonym: "hindlimb paralysis" EXACT []
is_obsolete: true

[Term]
id: SYMP:0000050
name: obsolete hunched posture
is_obsolete: true

[Term]
id: SYMP:0000051
name: hydrocephalus
comment: doid/symp duplicate
is_a: SYMP:0000387 ! head symptom

[Term]
id: SYMP:0000052
name: obsolete hyperemic liver
is_obsolete: true

[Term]
id: SYMP:0000053
name: obsolete hyperemic spleen
is_obsolete: true

[Term]
id: SYMP:0000054
name: hypergammaglobulinemia
is_a: SYMP:0000528 ! cardiovascular system symptom

[Term]
id: SYMP:0000055
name: obsolete hyperkeratotic plaques of surface of foot
is_obsolete: true

[Term]
id: SYMP:0000056
name: hyperpigmentation
def: "A skin and integumentary tissue symptom that is characterized by an excess pigmentation in a bodily part or tissue, as the skin." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=hyperpigmentation]
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000057
name: obsolete hyperplastic alveolar nodules
synonym: "han" EXACT []
is_obsolete: true

[Term]
id: SYMP:0000058
name: hyperreflexia
is_a: SYMP:0000249 ! reflex symptom

[Term]
id: SYMP:0000059
name: hypotension
is_a: SYMP:0019139 ! hemic system symptom

[Term]
id: SYMP:0000060
name: obsolete ill-thrift
is_obsolete: true

[Term]
id: SYMP:0000061
name: inflammation
def: "Inflammation is a general symptom where there is a local response to cellular injury that is marked by capillary dilatation, leukocytic infiltration, redness, heat, pain, swelling, and often loss of function and that serves as a mechanism initiating the elimination of noxious agents and of damaged tissue." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=inflammation]
is_a: SYMP:0000567 ! general symptom

[Term]
id: SYMP:0000062
name: obsolete inflammation of meninges
is_obsolete: true

[Term]
id: SYMP:0000063
name: intestinal hemorrhage
is_a: SYMP:0000459 ! digestive system symptom

[Term]
id: SYMP:0000064
name: joint pain
def: "A pain that is characterized by a pain situated, or occurring, in or around a joint." [url:https\://medlineplus.gov/ency/article/003261.htm]
synonym: "arthralgia" EXACT []
synonym: "arthromyalgia" EXACT []
is_a: SYMP:0000099 ! pain

[Term]
id: SYMP:0000065
name: obsolete joint swelling
is_obsolete: true

[Term]
id: SYMP:0000066
name: keratotic nodules of the skin
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000067
name: obsolete lameness
is_obsolete: true

[Term]
id: SYMP:0000068
name: laryngitis
comment: doid/symp duplicate
is_a: SYMP:0000385 ! throat symptom

[Term]
id: SYMP:0000069
name: laryngotracheitis
comment: doid/symp duplicate
synonym: "larynx and trachea inflammation" EXACT []
is_a: SYMP:0000385 ! throat symptom

[Term]
id: SYMP:0000070
name: lesions in myocardium
is_a: SYMP:0000528 ! cardiovascular system symptom

[Term]
id: SYMP:0000071
name: obsolete lesions in respiratory tract
is_obsolete: true

[Term]
id: SYMP:0000072
name: obsolete lesions in spleen
is_obsolete: true

[Term]
id: SYMP:0000073
name: obsolete lesions in thymus
is_obsolete: true

[Term]
id: SYMP:0000074
name: obsolete lesions in swim bladder
is_obsolete: true

[Term]
id: SYMP:0000075
name: lethargy
def: "A fatigue that is characterized by abnormal drowsiness." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=lethargy]
is_a: SYMP:0019177 ! fatigue

[Term]
id: SYMP:0000076
name: listlessness
synonym: "languid" EXACT []
is_a: SYMP:0000567 ! general symptom

[Term]
id: SYMP:0000077
name: obsolete localized cutaneous lesions
is_obsolete: true

[Term]
id: SYMP:0000078
name: obsolete loose droppings
is_obsolete: true

[Term]
id: SYMP:0000079
name: coordination symptom
def: "A nervous system symptom that is characterized by the harmonious functioning of interrelated organs and body parts; in particular the working together of muscle groups in the execution of complicated movements." [url:https\://medical-dictionary.thefreedictionary.com/coordinations]
is_a: SYMP:0000480 ! nervous system symptom

[Term]
id: SYMP:0000080
name: obsolete loss of coordination
is_obsolete: true

[Term]
id: SYMP:0000081
name: obsolete low grade fever
is_obsolete: true

[Term]
id: SYMP:0000082
name: lesions in lung
is_a: SYMP:0000514 ! respiratory system and chest symptom

[Term]
id: SYMP:0000083
name: lymphangitis
comment: doid/symp duplicate
is_a: SYMP:0019141 ! lymphatic system symptom

[Term]
id: SYMP:0000084
name: lymphoblastoma
is_a: SYMP:0019141 ! lymphatic system symptom

[Term]
id: SYMP:0000085
name: obsolete lymphocytic hyperplasia
is_obsolete: true

[Term]
id: SYMP:0000086
name: lymphopenia
comment: doid/symp duplicate
is_a: SYMP:0019141 ! lymphatic system symptom

[Term]
id: SYMP:0000087
name: massive hepatic necrosis
is_a: SYMP:0000045 ! hepatic necrosis

[Term]
id: SYMP:0000088
name: obsolete massive lymphadenopathy
is_obsolete: true

[Term]
id: SYMP:0000089
name: meningoencephalitis
def: "A nervous system symptom that is characterized by an inflammation of the brain and meninges." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=meningoencephalitis]
comment: doid/symp duplicate
is_a: SYMP:0000480 ! nervous system symptom

[Term]
id: SYMP:0000090
name: encephalitis
def: "A nervous system symptom that is characterized by inflammation of the brain tissue, which is typically caused by a viral infection, but it may also be caused by bacterial or parasitic infections, cancer, or certain drugs or toxins." [url:https\://www.cancer.gov/publications/dictionaries/cancer-terms/def/encephalitis]
comment: doid/symp duplicate
is_a: SYMP:0000480 ! nervous system symptom

[Term]
id: SYMP:0000091
name: mild encephalitis
def: "An encephalitis that is not intense (not severe)." [url:https\://www.macmillandictionary.com/us/dictionary/american/mild_1]
is_a: SYMP:0000090 ! encephalitis

[Term]
id: SYMP:0000092
name: skin lesion
def: "A skin and integumentary tissue symptom that is characterized by an abnormal change in structure of the skin that is especially circumscribed and well defined due to injury or disease." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=lesion]
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000093
name: muscle cramp
is_a: SYMP:0000183 ! muscle symptom

[Term]
id: SYMP:0000094
name: muscle weakness
is_a: SYMP:0000183 ! muscle symptom

[Term]
id: SYMP:0000095
name: myocarditis
comment: doid/symp duplicate
is_a: SYMP:0000528 ! cardiovascular system symptom

[Term]
id: SYMP:0000096
name: obsolete nasal discharge
is_obsolete: true

[Term]
id: SYMP:0000097
name: obsolete neck swelling
is_obsolete: true

[Term]
id: SYMP:0000098
name: nephritis
def: "A urinary system symptom that is characterized by the acute or chronic inflammation of the kidney affecting the structure (as of the glomerulus or parenchyma) and caused by infection, a degenerative process, or vascular disease." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=nephritis]
comment: doid/symp duplicate
is_a: SYMP:0000486 ! urinary system symptom

[Term]
id: SYMP:0000099
name: pain
def: "A sensation perception that is characterized by an unpleasant sensation that usually indicates the body is threatened or damaged. The sensation may be sharp or dull, short-lived or chronic, intermittent or continual, confined to one area or spread over the entire body." [url:http\://www.nationalpainfoundation.org/MyTreatment/articles/Cancer_PainDefinitions.asp]
is_a: SYMP:0000892 ! sensation perception

[Term]
id: SYMP:0000100
name: lesions in pancreas
is_a: SYMP:0000459 ! digestive system symptom

[Term]
id: SYMP:0000101
name: obsolete partial paralysis
synonym: "paresis" EXACT []
is_obsolete: true

[Term]
id: SYMP:0000102
name: peritonitis
def: "A skin and integumentary tissue symptom that is characterized by an inflammation of the peritoneum." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=peritonitis]
comment: doid/symp duplicate
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000103
name: obsolete persistent lymphocytosis
is_obsolete: true

[Term]
id: SYMP:0000104
name: obsolete petechial hemorrhages
is_obsolete: true

[Term]
id: SYMP:0000105
name: obsolete photosensitivity
is_obsolete: true

[Term]
id: SYMP:0000106
name: plasmacytosis
is_a: SYMP:0019139 ! hemic system symptom

[Term]
id: SYMP:0000107
name: pleural effusion
def: "A skin and integumentary tissue symptom that is characterized by an exudation of fluid from the blood or lymph into a pleural cavity." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=pleural%20effusion]
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000108
name: obsolete portal hepatitis
is_obsolete: true

[Term]
id: SYMP:0000109
name: mouth papules
is_a: SYMP:0000386 ! mouth symptom

[Term]
id: SYMP:0000110
name: obsolete proliferative mouth papules
is_obsolete: true

[Term]
id: SYMP:0000111
name: obsolete proliferative skin lesions
is_obsolete: true

[Term]
id: SYMP:0000112
name: tracheitis
comment: doid/symp duplicate
is_a: SYMP:0000385 ! throat symptom

[Term]
id: SYMP:0000113
name: obsolete proliferative tracheitis
is_obsolete: true

[Term]
id: SYMP:0000114
name: thrombocytopenia
comment: doid/symp duplicate
is_a: SYMP:0019139 ! hemic system symptom

[Term]
id: SYMP:0000115
name: obsolete prolonged thrombocytopenia
is_obsolete: true

[Term]
id: SYMP:0000116
name: prostration
def: "Prostration is a general symptom characterized by complete physical or mental exhaustion." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=prostration]
is_a: SYMP:0000567 ! general symptom

[Term]
id: SYMP:0000117
name: obsolete pustular skin lesions
is_obsolete: true

[Term]
id: SYMP:0000118
name: rales
def: "An abnormal chest sound that is characterized by the clicking, rattling, or crackling noises heard on auscultation of (listening to) the lung with a stethoscope during inhalation. The sounds are caused by the 'popping open' of small airways and alveoli collapsed by fluid, exudate, or lack of aeration during expiration. The word 'rales' derives from the French word rale meaning 'rattle'. Rales can be heard in patients with pneumonia, atelectasis, pulmonary fibrosis, acute bronchitis, or bronchiectasis. Pulmonary edema secondary to left-sided congestive heart failure can also cause rales." [url:http\://en.wikipedia.org/wiki/Rales]
synonym: "crackles" EXACT []
synonym: "crepitations" EXACT []
is_a: SYMP:0000587 ! abnormal chest sound

[Term]
id: SYMP:0000119
name: obsolete reddening
is_obsolete: true

[Term]
id: SYMP:0000120
name: obsolete retinal inflammation
is_obsolete: true

[Term]
id: SYMP:0000121
name: obsolete rhinitis
comment: doid/symp duplicate - reviewed 10/2022 & determined to be a disease
is_obsolete: true

[Term]
id: SYMP:0000122
name: obsolete salivary gland swelling
is_obsolete: true

[Term]
id: SYMP:0000123
name: obsolete sclerodermoid plaques
is_obsolete: true

[Term]
id: SYMP:0000124
name: seizure
is_a: SYMP:0000480 ! nervous system symptom

[Term]
id: SYMP:0000125
name: liver inflammation
is_a: SYMP:0000180 ! liver symptom

[Term]
id: SYMP:0000126
name: obsolete self-limiting liver inflammation
is_obsolete: true

[Term]
id: SYMP:0000127
name: severe backache
synonym: "intense back pain" EXACT []
is_a: SYMP:0000006 ! backache

[Term]
id: SYMP:0000128
name: conjunctivitis
comment: doid/symp duplicate
is_a: SYMP:0020034 ! conjunctiva symptom

[Term]
id: SYMP:0000129
name: severe conjunctivitis
is_a: SYMP:0000128 ! conjunctivitis

[Term]
id: SYMP:0000130
name: severe headache
is_a: SYMP:0000504 ! headache

[Term]
id: SYMP:0000131
name: severe joint pain
def: "A joint pain that is characterized by a pain situated, or occurring, in or around a joint that is intense (severe)." [url:https\://medical-dictionary.thefreedictionary.com/severe]
synonym: "intense join pain" EXACT []
is_a: SYMP:0000064 ! joint pain

[Term]
id: SYMP:0000132
name: necrosis
def: "Necrosis is a general symptom where death of a portion of tissue differentially affected by local injury (as loss of blood supply, corrosion, burning, or the local lesion of a disease)." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=necrosis]
is_a: SYMP:0000567 ! general symptom

[Term]
id: SYMP:0000133
name: severe necrosis
is_a: SYMP:0000132 ! necrosis

[Term]
id: SYMP:0000134
name: sinusitis
comment: doid/symp duplicate
is_a: SYMP:0000388 ! nose symptom

[Term]
id: SYMP:0000135
name: obsolete skin papules
is_obsolete: true

[Term]
id: SYMP:0000136
name: skin ulcer
def: "A skin lesion that is characterized by a break in skin with loss of surface tissue, disintegration and necrosis of epithelial tissue, and often pus." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=ulcer]
is_a: SYMP:0000092 ! skin lesion

[Term]
id: SYMP:0000137
name: obsolete slight cough
is_obsolete: true

[Term]
id: SYMP:0000138
name: obsolete slight pyrexia
is_obsolete: true

[Term]
id: SYMP:0000139
name: sneezing
def: "A respiratory system and chest symptom that is characterized by a sudden violent spasmodic audible expiration of breath through the nose and mouth especially as a reflex act following irritation of the nasal mucous membrane." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=sneezing]
is_a: SYMP:0000514 ! respiratory system and chest symptom

[Term]
id: SYMP:0000140
name: obsolete spastic paralysis
is_obsolete: true

[Term]
id: SYMP:0000141
name: spasticity
def: "A nervous system symptom that is characterized by an abnormal increase in muscle tone or stiffness of muscle, which might interfere with movement, speech, or be associated with discomfort or pain." [url:https\://www.ninds.nih.gov/health-information/disorders/spasticity]
is_a: SYMP:0000480 ! nervous system symptom

[Term]
id: SYMP:0000142
name: obsolete spleen hemorrhages
is_obsolete: true

[Term]
id: SYMP:0000143
name: obsolete spleen infiltrates
is_obsolete: true

[Term]
id: SYMP:0000144
name: obsolete bronchopneumonia
def: "A pneumonia that is characterized by acute inflammation of the bronchi, accompanied by inflamed patches in the nearby lobules of the lungs" [url:https\://en.wikipedia.org/wiki/Bronchopneumonia]
comment: doid/symp duplicate - reviewed 10/2022 & determined to be a disease
synonym: "bronchial pneumonia" EXACT []
synonym: "lobular pneumonia" EXACT []
is_obsolete: true
replaced_by: SYMP:0020057

[Term]
id: SYMP:0000145
name: obsolete splitting of tissues
is_obsolete: true

[Term]
id: SYMP:0000146
name: feces and droppings symptom
synonym: "fecal" EXACT []
is_a: SYMP:0000459 ! digestive system symptom

[Term]
id: SYMP:0000147
name: steatorrhea
comment: doid/symp duplicate
is_a: SYMP:0000146 ! feces and droppings symptom

[Term]
id: SYMP:0000148
name: obsolete sudden onset of fever
is_obsolete: true

[Term]
id: SYMP:0000149
name: obsolete sudden onset of severe chills
is_obsolete: true

[Term]
id: SYMP:0000150
name: obsolete swollen cervical lymphnodes
is_obsolete: true

[Term]
id: SYMP:0000151
name: obsolete systemic infection
is_obsolete: true

[Term]
id: SYMP:0000152
name: obsolete systemic necrosis
is_obsolete: true

[Term]
id: SYMP:0000153
name: vasculitis
comment: doid/symp duplicate
is_a: SYMP:0019139 ! hemic system symptom

[Term]
id: SYMP:0000154
name: obsolete systemic vasculitis
is_obsolete: true

[Term]
id: SYMP:0000155
name: obsolete tarry droppings
is_obsolete: true

[Term]
id: SYMP:0000156
name: thirst
def: "Thirst is a general symptom characterized by a sensation of dryness in the mouth and throat associated with a desire for liquids." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=thirst]
is_a: SYMP:0000567 ! general symptom

[Term]
id: SYMP:0000157
name: thymus symptom
is_a: SYMP:0019138 ! immune system symptom

[Term]
id: SYMP:0000158
name: spleen symptom
is_a: SYMP:0019138 ! immune system symptom

[Term]
id: SYMP:0000159
name: obsolete thymus atrophy
is_obsolete: true

[Term]
id: SYMP:0000160
name: tracheobronchitis
is_a: SYMP:0000385 ! throat symptom

[Term]
id: SYMP:0000161
name: obsolete transient fever
is_obsolete: true

[Term]
id: SYMP:0000162
name: tremor
def: "Tremor is a generial symptom characterized by a trembling or shaking usually from physical weakness, emotional stress, or disease." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=tremor]
is_a: SYMP:0000567 ! general symptom

[Term]
id: SYMP:0000163
name: obsolete ulcerative dermal vesicles
is_obsolete: true

[Term]
id: SYMP:0000164
name: incoordination
def: "A coordination symptom that is characterized by a loss of complicated body movements, which may be caused by disease, injury, or toxins." [url:https\://www.merckmanuals.com/home/brain\,-spinal-cord\,-and-nerve-disorders/movement-disorders/coordination-disorders]
synonym: "lack of coordination" EXACT []
is_a: SYMP:0000079 ! coordination symptom

[Term]
id: SYMP:0000165
name: obsolete upper respiratory distress
is_obsolete: true

[Term]
id: SYMP:0000166
name: obsolete vascular lesions
is_obsolete: true

[Term]
id: SYMP:0000167
name: obsolete vascular necrosis
is_obsolete: true

[Term]
id: SYMP:0000168
name: obsolete vein swelling
is_obsolete: true

[Term]
id: SYMP:0000169
name: obsolete vesicles on feet
is_obsolete: true

[Term]
id: SYMP:0000170
name: obsolete vesicles on hoof corona
is_obsolete: true

[Term]
id: SYMP:0000171
name: obsolete vesicles on mouth
is_obsolete: true

[Term]
id: SYMP:0000172
name: obsolete vesicles on teats
is_obsolete: true

[Term]
id: SYMP:0000173
name: obsolete vesicular lesions on lip border
synonym: "cold sore" EXACT []
is_obsolete: true

[Term]
id: SYMP:0000174
name: wasting
def: "A nutrition, metabolism, and development symptom that is characterized by the unintended loss of weight and lean body tissue characteristic of many diseases (as cancer, tuberculosis, and AIDS)." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=wasting]
is_a: SYMP:0000473 ! nutrition, metabolism, and development symptom

[Term]
id: SYMP:0000175
name: obsolete watery diarrhea
is_obsolete: true

[Term]
id: SYMP:0000176
name: obsolete watery ocular discharge
is_obsolete: true

[Term]
id: SYMP:0000177
name: weakness
is_a: SYMP:0000567 ! general symptom

[Term]
id: SYMP:0000178
name: weight loss
alt_id: SYMP:0000476
def: "A weight symptom that is characterized by a reduction of the total body mass, by a mean loss of fluid, body fat (adipose tissue), or lean mass (namely bone mineral deposits, muscle, tendon, and other connective tissue). Weight loss can either occur unintentionally because of malnourishment or an underlying disease." [url:https\://en.wikipedia.org/wiki/Weight_loss]
synonym: "loss of weight" EXACT []
xref: ICD9CM_2005:783.21
xref: UMLS_CUI:C0043096
xref: UMLS_ICD9CM_2005_AUI:A1605347
is_a: SYMP:0020012 ! weight symptom

[Term]
id: SYMP:0000179
name: obsolete wet droppings
is_obsolete: true

[Term]
id: SYMP:0000180
name: liver symptom
is_a: SYMP:0000459 ! digestive system symptom

[Term]
id: SYMP:0000181
name: obsolete yellow liver
is_obsolete: true

[Term]
id: SYMP:0000182
name: bubo
synonym: "buboes" EXACT []
is_a: SYMP:0019155 ! lymphadenitis

[Term]
id: SYMP:0000183
name: muscle symptom
is_a: SYMP:0000891 ! musculoskeletal system symptom

[Term]
id: SYMP:0000184
name: change in skin color
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000185
name: weariness
def: "A fatigue that is characterized by a feeling of exhaustion in strength, endurance, and vigor." [url:https\://www.merriam-webster.com/dictionary/weary]
is_a: SYMP:0019177 ! fatigue

[Term]
id: SYMP:0000186
name: exhaustion
def: "A fatigue that is characterized by a feeling of weariness (bodily or mental) or feeling of weakness.  Exhaustion is a shorter-lived form of fatigue that can be experienced emotionally, mentally, and physically." [url:https\://wellteq.co/insights/mental-health/fatigue-burnout-and-exhaustion-whats-the-difference, url:https\://www.dictionary.com/browse/fatigue]
is_a: SYMP:0019177 ! fatigue

[Term]
id: SYMP:0000187
name: tiredness
def: "A fatigue that is characterized by a feeling of a lessened capacity for work and reduced efficiency of accomplishment, usually accompanied by a sense of weariness and fatigue." [url:https\://www.medicinenet.com/tired/definition.htm]
is_a: SYMP:0019177 ! fatigue

[Term]
id: SYMP:0000188
name: abdominal discomfort
is_a: SYMP:0000461 ! abdominal symptom

[Term]
id: SYMP:0000189
name: postural reaction
is_a: SYMP:0000891 ! musculoskeletal system symptom

[Term]
id: SYMP:0000190
name: wheelbarrowing
is_a: SYMP:0000189 ! postural reaction

[Term]
id: SYMP:0000191
name: obsolete hemistanding
is_obsolete: true

[Term]
id: SYMP:0000192
name: obsolete hemiwalking
is_obsolete: true

[Term]
id: SYMP:0000193
name: hopping
is_a: SYMP:0000189 ! postural reaction

[Term]
id: SYMP:0000194
name: conscious proprioception
is_a: SYMP:0000189 ! postural reaction

[Term]
id: SYMP:0000195
name: abnormal hemiwalking hemistanding
is_a: SYMP:0000189 ! postural reaction

[Term]
id: SYMP:0000196
name: reproductive system symptom
is_a: SYMP:0000462 ! symptom

[Term]
id: SYMP:0000197
name: abortion
def: "A reproductive system symptom that is characterized by the expulsion of a fetus at any time before completion of pregnancy and is often due to infection." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=abortion]
synonym: "infectious abortion" EXACT []
is_a: SYMP:0000196 ! reproductive system symptom

[Term]
id: SYMP:0000198
name: miscarriage
def: "A reproductive system symptom that is characterized by the spontaneous expulsion of a human fetus before it is viable and especially between the 12th and 28th weeks of gestation." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=miscarriage]
is_a: SYMP:0000196 ! reproductive system symptom

[Term]
id: SYMP:0000199
name: spontaneous abortion
def: "An abortion that is characterized by the natural occurring expulsion of a nonviable fetus." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=spontaneous%20abortion]
is_a: SYMP:0000197 ! abortion

[Term]
id: SYMP:0000200
name: acute arthritis
is_a: SYMP:0019169 ! arthritis

[Term]
id: SYMP:0000201
name: acute meningoencephalitis
def: "A meningoencephalitis that is characterized by a severe and sudden onset." [url:https\://medlineplus.gov/ency/imagepages/18126.htm]
is_a: SYMP:0000089 ! meningoencephalitis

[Term]
id: SYMP:0000202
name: acute painful vision loss
is_a: SYMP:0000099 ! pain

[Term]
id: SYMP:0000203
name: obsolete acute respiratory distress
is_obsolete: true

[Term]
id: SYMP:0000204
name: obsolete acute suppurative lesions
is_obsolete: true

[Term]
id: SYMP:0000205
name: salivary gland symptom
is_a: SYMP:0000459 ! digestive system symptom

[Term]
id: SYMP:0000206
name: acute suppurative parotiditis
is_a: SYMP:0000205 ! salivary gland symptom

[Term]
id: SYMP:0000207
name: afebrile
def: "A fever that is characterized by the state of being free from fever." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=afebrile]
is_a: SYMP:0000613 ! fever

[Term]
id: SYMP:0000208
name: anemia
comment: doid/symp duplicate - reviewed 10/2022, both DO & SYMP
synonym: "anaemia" EXACT []
is_a: SYMP:0019139 ! hemic system symptom

[Term]
id: SYMP:0000209
name: ischemia
is_a: SYMP:0019139 ! hemic system symptom

[Term]
id: SYMP:0000210
name: photophobia
synonym: "light intolerance" EXACT []
is_a: SYMP:0019165 ! light sensitivity

[Term]
id: SYMP:0000211
name: asthenopia
comment: doid/symp duplicate
synonym: "eye weakness" EXACT []
synonym: "rapid eye fatigue" EXACT []
is_a: SYMP:0019163 ! eye symptom

[Term]
id: SYMP:0000212
name: eye strain
is_a: SYMP:0019163 ! eye symptom

[Term]
id: SYMP:0000213
name: agraphia
def: "An aphasia that is characterized by a pathological loss of the ability to write." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=agraphia]
synonym: "inability to write" EXACT []
is_a: SYMP:0000508 ! aphasia

[Term]
id: SYMP:0000214
name: anomia
def: "An aphasia that is characterized by a severe problem with recalling words or names." [url:http\://en.wikipedia.org/wiki/Anomia]
comment: doid/symp duplicate - reviewed 10/2022, both DO & SYMP
synonym: "amnesic aphasia" EXACT []
synonym: "amnestic aphasia" EXACT []
synonym: "anomic aphasia" EXACT []
synonym: "inability to name objects" EXACT []
synonym: "nominal aphasia" EXACT []
is_a: SYMP:0000508 ! aphasia

[Term]
id: SYMP:0000215
name: inability to comprehend speech
def: "An aphasia that is characterized by a loss of ability to comprehend speech." [url:https\://www.healthline.com/health/aphasia#causes, url:https\://www.nidcd.nih.gov/health/aphasia]
is_a: SYMP:0000508 ! aphasia

[Term]
id: SYMP:0000216
name: inability to speak
def: "An aphasia that is characterized by a loss of ability to speak." [url:https\://www.healthline.com/health/aphasia#causes, url:https\://www.nidcd.nih.gov/health/aphasia]
is_a: SYMP:0000508 ! aphasia

[Term]
id: SYMP:0000217
name: inability to form words
def: "An aphasia that is characterized by a loss of ability to form words." [url:https\://www.healthline.com/health/aphasia#causes, url:https\://www.nidcd.nih.gov/health/aphasia]
is_a: SYMP:0000508 ! aphasia

[Term]
id: SYMP:0000218
name: poor enunciation
def: "An aphasia that is characterized by a loss of ability to properly enunciate words." [url:https\://www.healthline.com/health/aphasia#causes, url:https\://www.nidcd.nih.gov/health/aphasia]
is_a: SYMP:0000508 ! aphasia

[Term]
id: SYMP:0000219
name: receptive aphasia
def: "An inability to comprehend speech that is characterized by an inability to understand spoken, written, or tactile speech symbols that results from damage (as by a brain lesion) to an area of the brain (as Wernicke's area) concerned with language." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=sensory%20aphasia]
synonym: "fluent aphasia" EXACT []
synonym: "inability to perceive pitch, rhythm, and emotional tone of speech" EXACT []
synonym: "sensory aphasia" EXACT []
synonym: "Wernicke's aphasia" EXACT []
is_a: SYMP:0000215 ! inability to comprehend speech

[Term]
id: SYMP:0000220
name: areflexia
synonym: "absence of neurological reflexes" EXACT []
is_a: SYMP:0000249 ! reflex symptom

[Term]
id: SYMP:0000221
name: absence of knee jerk reflex
is_a: SYMP:0000220 ! areflexia

[Term]
id: SYMP:0000222
name: limb weakness
synonym: "extremities weakness" EXACT []
is_a: SYMP:0000094 ! muscle weakness

[Term]
id: SYMP:0000223
name: arm weakness
is_a: SYMP:0000222 ! limb weakness

[Term]
id: SYMP:0000224
name: leg weakness
is_a: SYMP:0000222 ! limb weakness

[Term]
id: SYMP:0000225
name: asthenia
comment: doid/symp duplicate
synonym: "loss of strength" EXACT []
is_a: SYMP:0000567 ! general symptom

[Term]
id: SYMP:0000226
name: atrial fibrillation
def: "A cardiac fibrillation consisting of a very rapid uncoordinated contractions of the atria of the heart resulting in a lack of synchronism between heartbeat and pulse beat." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=atrial%20fibrillation]
comment: doid/symp duplicate - reviewed 10/2022, both DO & SYMP
synonym: "a-fib" EXACT []
synonym: "AF" EXACT []
synonym: "AFib" EXACT []
synonym: "auricular fibrillation" EXACT []
is_a: SYMP:0000898 ! cardiac fibrillation

[Term]
id: SYMP:0000227
name: blood vessel infection
is_a: SYMP:0000528 ! cardiovascular system symptom

[Term]
id: SYMP:0000228
name: hemorrhagic diarrhea
is_a: SYMP:0000570 ! diarrhea

[Term]
id: SYMP:0000229
name: bloody stool
synonym: "blood in stool" EXACT []
is_a: SYMP:0000146 ! feces and droppings symptom

[Term]
id: SYMP:0000230
name: body ache
is_a: SYMP:0000099 ! pain

[Term]
id: SYMP:0000231
name: bradycardia
def: "Bradycardia is a cardiovascular system symptom consisting of a relatively slow heart action whether physiological or pathological." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=bradycardia]
is_a: SYMP:0000287 ! arrhythmia

[Term]
id: SYMP:0000232
name: bronchiolitis
def: "A respiratory system and chest symptom that is characterized by an inflammation of the bronchioles." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=bronchiolitis]
comment: doid/symp duplicate
synonym: "bronchioles inflammation" EXACT []
is_a: SYMP:0000514 ! respiratory system and chest symptom

[Term]
id: SYMP:0000233
name: inability to think clearly
synonym: "clouded sensorium" EXACT []
synonym: "decreased sensorium" EXACT []
is_a: SYMP:0000482 ! alteration of consciousness

[Term]
id: SYMP:0000234
name: cloudy cornea
is_a: SYMP:0000239 ! cornea symptom

[Term]
id: SYMP:0000235
name: colic
def: "A pain that is characterized by the condition marked by recurrent episodes of prolonged and uncontrollable crying and irritability in an otherwise healthy infant that is of unknown cause and usually subsides after three to four months of age." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=colic]
is_a: SYMP:0000099 ! pain

[Term]
id: SYMP:0000236
name: colicky pain
def: "A pain that is characterized by an attack of acute abdominal pain localized in a hollow organ or part (as the small intestine, ureter, or bile duct) and often caused by spasm, obstruction, or twisting." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=colic]
is_a: SYMP:0000099 ! pain

[Term]
id: SYMP:0000237
name: congestion
def: "A respiratory system and chest symptom that is characterized by an excessive accumulation especially of blood or mucus." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=congestion]
synonym: "blocked nose" EXACT []
synonym: "nasal blockage" EXACT []
synonym: "nasal obstruction" EXACT []
synonym: "stuffed up nose" EXACT []
synonym: "stuffy nose" EXACT []
is_a: SYMP:0000514 ! respiratory system and chest symptom

[Term]
id: SYMP:0000238
name: continuous profuse salivation
is_a: SYMP:0000373 ! salivation

[Term]
id: SYMP:0000239
name: cornea symptom
is_a: SYMP:0019163 ! eye symptom

[Term]
id: SYMP:0000240
name: corneal opacity
is_a: SYMP:0000239 ! cornea symptom

[Term]
id: SYMP:0000241
name: corneal ulcers
is_a: SYMP:0000239 ! cornea symptom

[Term]
id: SYMP:0000242
name: cough with bloody sputum
def: "A cough that is characterized by production and expectoration (bringing up) of sputum that is bright red or pink and frothy." [url:https\://www.webmd.com/lung/coughing-up-blood]
is_a: SYMP:0000614 ! cough

[Term]
id: SYMP:0000243
name: cyclic fever
alt_id: SYMP:0000884
def: "A fever that is characterized by occurring during periodic episodes." [url:http\://en.wikipedia.org/wiki/Fever#Types, url:http\://www.wrongdiagnosis.com/sym/cyclic_fever_in_children.htm]
synonym: "intermittent fever" RELATED []
synonym: "recurrent fever" EXACT []
is_a: SYMP:0000613 ! fever

[Term]
id: SYMP:0000244
name: alteration of appetite
is_a: SYMP:0000473 ! nutrition, metabolism, and development symptom

[Term]
id: SYMP:0000245
name: decreased appetite
def: "An alteration of appetite that is characterized by a reduced desire to eat." [url:https\://www.healthline.com/health/appetite-decreased]
synonym: "poor appetite" EXACT []
is_a: SYMP:0000244 ! alteration of appetite

[Term]
id: SYMP:0000246
name: increased appetite
def: "An alteration of appetite that is characterized by an desire to eat, an excess desire for food." [url:https\://medlineplus.gov/ency/article/003134.htm]
is_a: SYMP:0000244 ! alteration of appetite

[Term]
id: SYMP:0000247
name: proprioception symptom
def: "A neurological and physiological symptom that is characterized by one's body’s ability to sense movement, action, and location and results from sensory receptors in one's nervous system and body (muscles, joints, and tendons)." [url:https\://www.webmd.com/brain/what-is-proprioception]
is_a: SYMP:0000410 ! neurological and physiological symptom

[Term]
id: SYMP:0000248
name: decreased conscious proprioception
def: "A proprioception symptom that is characterized by a decreased ability of an organism to consciously process the reception of stimuli produced within the organism." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=proprioception]
is_a: SYMP:0000247 ! proprioception symptom

[Term]
id: SYMP:0000249
name: reflex symptom
is_a: SYMP:0000480 ! nervous system symptom

[Term]
id: SYMP:0000250
name: decreased flexor withdrawal reflex
is_a: SYMP:0000249 ! reflex symptom

[Term]
id: SYMP:0000251
name: dermal abscess
def: "A skin and integumentary tissue symptom that is characterized by a pus-filled pocket in the skin, similar to a pimple, but larger and deeper.  The pocket is filled with bacteria, white blood cells, and dead skin and typcally result from the bacteria Staphylococcus aureus prentrating the skin through a cut or hair follicle." [url:https\://jamanetwork.com/journals/jama/fullarticle/2677448]
synonym: "cutaneous abscess" EXACT []
synonym: "dermal abscesses" EXACT []
synonym: "skin abscess" EXACT []
synonym: "subcutaneous abscess" EXACT []
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000252
name: diffuse rash
def: "A rash characterized by large patches of red skin, without overlying changes in the epidermis." [url:https\://www.drugwatch.com/health/rash-and-skin-disorders/erythema/, url:https\://www.sciencedirect.com/topics/medicine-and-dentistry/erythema]
synonym: "diffuse erythema" EXACT []
is_a: SYMP:0000487 ! rash

[Term]
id: SYMP:0000253
name: anisocoria
synonym: "enlargement of one pupil" EXACT []
synonym: "pupils of different size" EXACT []
is_a: SYMP:0019163 ! eye symptom

[Term]
id: SYMP:0000254
name: dilated pupil
is_a: SYMP:0000417 ! pupil symptom

[Term]
id: SYMP:0000255
name: diminished gastro-intestinal motility
is_a: SYMP:0000459 ! digestive system symptom

[Term]
id: SYMP:0000256
name: diminished gag reflex
is_a: SYMP:0000249 ! reflex symptom

[Term]
id: SYMP:0000257
name: absent gag reflex
is_a: SYMP:0000220 ! areflexia

[Term]
id: SYMP:0000258
name: double vision
synonym: "diplopia" EXACT []
is_a: SYMP:0000320 ! vision symptom

[Term]
id: SYMP:0000259
name: dry hacking cough
def: "A dry cough that is characterized by a rough and loud sound." [url:https\://en.wiktionary.org/wiki/hacking_cough]
is_a: SYMP:0000025 ! dry cough

[Term]
id: SYMP:0000260
name: dry mouth
is_a: SYMP:0000386 ! mouth symptom

[Term]
id: SYMP:0000261
name: dry mucous membrane
synonym: "dry mucous membranes" EXACT []
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000262
name: endocarditis
comment: doid/symp duplicate
is_a: SYMP:0000528 ! cardiovascular system symptom

[Term]
id: SYMP:0000263
name: epididymitis
def: "A reproductive system symptom that is characterized by an inflammation of the epididymis." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=epididymitis]
comment: doid/symp duplicate
synonym: "inflammation of the epididymis" EXACT []
is_a: SYMP:0000196 ! reproductive system symptom

[Term]
id: SYMP:0000264
name: epididymorchitis
def: "A reproductive system symptom that is characterized by inflammation of the epididymis and/or testicle (testis)." [url:https\://patient.info/mens-health/scrotal-lumps-pain-and-swelling/epididymo-orchitis]
synonym: "epididymo-orchitis" EXACT []
is_a: SYMP:0000196 ! reproductive system symptom

[Term]
id: SYMP:0000265
name: obsolete absence seizure
comment: reviewed 10/2022 & determined to be a disease
synonym: "petit mal seizure" EXACT []
is_obsolete: true

[Term]
id: SYMP:0000266
name: focal seizure
synonym: "partial seizure" EXACT []
is_a: SYMP:0000124 ! seizure

[Term]
id: SYMP:0000267
name: generalized seizure
is_a: SYMP:0000124 ! seizure

[Term]
id: SYMP:0000268
name: tonic-clonic seizure
synonym: "grand mal seizure" EXACT []
is_a: SYMP:0000267 ! generalized seizure

[Term]
id: SYMP:0000269
name: epileptic seizure
is_a: SYMP:0000124 ! seizure

[Term]
id: SYMP:0000270
name: simple partial seizure
is_a: SYMP:0000266 ! focal seizure

[Term]
id: SYMP:0000271
name: complex partial seizure
is_a: SYMP:0000266 ! focal seizure

[Term]
id: SYMP:0000272
name: myoclonic seizure
is_a: SYMP:0000267 ! generalized seizure

[Term]
id: SYMP:0000273
name: clonic seizure
is_a: SYMP:0000267 ! generalized seizure

[Term]
id: SYMP:0000274
name: tonic seizure
is_a: SYMP:0000267 ! generalized seizure

[Term]
id: SYMP:0000275
name: atonic seizure
is_a: SYMP:0000267 ! generalized seizure

[Term]
id: SYMP:0000276
name: obsolete excess pericardial fluid
is_obsolete: true

[Term]
id: SYMP:0000277
name: excess salivation
synonym: "profuse salivation" EXACT []
is_a: SYMP:0000373 ! salivation

[Term]
id: SYMP:0000278
name: extensive ulcer
is_a: SYMP:0000136 ! skin ulcer

[Term]
id: SYMP:0000279
name: extreme exhaustion
def: "An exhaustion that is characterized by exceeding the ordinary, usual, or expected." [url:https\://www.merriam-webster.com/dictionary/extreme]
is_a: SYMP:0000186 ! exhaustion

[Term]
id: SYMP:0000280
name: extreme fatigue
def: "A fatigue that is characterized by exceeding the ordinary, usual, or expected." [url:https\://www.merriam-webster.com/dictionary/extreme]
is_a: SYMP:0019177 ! fatigue

[Term]
id: SYMP:0000281
name: eye discharge
synonym: "ocular discharge" EXACT []
is_a: SYMP:0019163 ! eye symptom

[Term]
id: SYMP:0000282
name: fixed dilated pupils
is_a: SYMP:0000254 ! dilated pupil

[Term]
id: SYMP:0000283
name: facial paralysis
comment: doid/symp duplicate
is_a: SYMP:0000030 ! paralysis

[Term]
id: SYMP:0000284
name: fixed pupil
synonym: "fixed pupils" EXACT []
is_a: SYMP:0019163 ! eye symptom

[Term]
id: SYMP:0000285
name: flaccid paralysis
def: "A paralysis that is charicterized by a lack of muscle tone in the affected muscles and in which tendon reflexes are decreased or absent." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=flaccid%20paralysis]
is_a: SYMP:0000030 ! paralysis

[Term]
id: SYMP:0000286
name: obsolete floppy head
comment: reviewed 10/2022 & determined to be a disease
is_obsolete: true

[Term]
id: SYMP:0000287
name: arrhythmia
alt_id: SYMP:0000288
alt_id: SYMP:0000667
alt_id: SYMP:0000668
def: "Arrhythmia is a cardiovascular system symptom consisting of an alteration in rhythm of the heartbeat either in time or force." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=arrhythmia]
synonym: "abnormal heart beat" EXACT []
synonym: "abnormal heart rhythm" EXACT []
synonym: "dysrhythmia" EXACT []
synonym: "fluctuation of heart rate" RELATED []
synonym: "heart rhythm symptom" EXACT []
synonym: "irregular heartbeat" EXACT []
is_a: SYMP:0000528 ! cardiovascular system symptom

[Term]
id: SYMP:0000288
name: obsolete fluctuation of heart rate
is_obsolete: true
replaced_by: SYMP:0000287

[Term]
id: SYMP:0000289
name: eczema
def: "A skin and integumentary tissue symptom that is characterized by an inflammatory condition of the skin with redness, itching, and oozing vesicular lesions, which become scaly, crusted, or hardened." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=eczema]
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000290
name: belching
def: "Belching is a digestive system symptom involving the sudden expulsion of gas from the stomach through the mouth." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=belching]
synonym: "eructation" EXACT []
is_a: SYMP:0000459 ! digestive system symptom

[Term]
id: SYMP:0000291
name: gas pain
is_a: SYMP:0000099 ! pain

[Term]
id: SYMP:0000292
name: heart failure
is_a: SYMP:0000528 ! cardiovascular system symptom

[Term]
id: SYMP:0000293
name: hemiparesis
def: "A paralysis that is characterized by a weakness or the inability to move on one side of the body." [url:https\://www.stroke.org/en/about-stroke/effects-of-stroke/physical-effects-of-stroke/physical-impact/hemiparesis]
is_a: SYMP:0000030 ! paralysis

[Term]
id: SYMP:0000294
name: hemolysis
synonym: "haemolysis" EXACT []
is_a: SYMP:0019139 ! hemic system symptom

[Term]
id: SYMP:0000295
name: hepatic abscess
def: "hepatic abscess is a liver symptom characterized by a pus-filled mass in the liver that can develop from injury to the liver or an intraabdominal infection disseminated from the portal circulation." [url:https\://www.ncbi.nlm.nih.gov/books/NBK538230/#\:~\:text=A%20liver%20abscess%20is%20defined\,caused%20by%20parasites%20and%20fungi.]
synonym: "hepatic abscesses" EXACT []
is_a: SYMP:0000180 ! liver symptom

[Term]
id: SYMP:0000296
name: hepatic dysfunction
is_a: SYMP:0000180 ! liver symptom

[Term]
id: SYMP:0000297
name: hilar lymphadenitis
is_a: SYMP:0019155 ! lymphadenitis

[Term]
id: SYMP:0000298
name: hoarse voice
is_a: SYMP:0000559 ! voice disturbance

[Term]
id: SYMP:0000299
name: hyperemia
def: "Hyperemia is a hemic system symptom consisting of an excess of blood in a body part as from an increased flow of blood due to vasodilation." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=hyperemia]
synonym: "hyperaemia" EXACT []
synonym: "hyperemic" EXACT []
is_a: SYMP:0019139 ! hemic system symptom

[Term]
id: SYMP:0000300
name: hyperesthesia
def: "A sensation perception that is characterized by an increased sensitivity to stimulation." [url:http\://www.nationalpainfoundation.org/MyTreatment/articles/Cancer_PainDefinitions.asp]
synonym: "hyperaesthesia" EXACT []
is_a: SYMP:0000892 ! sensation perception

[Term]
id: SYMP:0000301
name: hypopyon
comment: doid/symp duplicate
is_a: SYMP:0019163 ! eye symptom

[Term]
id: SYMP:0000302
name: hypothermia
def: "A neurological and physiological symptom that is characterized by a subnormal temperature of the body, as defined by a temperature under 36.6 degrees Celcius (97.8 degrees Fahrenheit)." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=hypothermia]
is_a: SYMP:0000410 ! neurological and physiological symptom

[Term]
id: SYMP:0000303
name: hypoxemia
synonym: "hypoxaemia" EXACT []
is_a: SYMP:0019139 ! hemic system symptom

[Term]
id: SYMP:0000304
name: impaired coordination
def: "A coordination symptom that is characterized by weakened or imperfect body complicated  movement, which may be caused by disease, injury, or toxins." [url:https\://www.healthline.com/health/movement-uncoordinated, url:https\://www.merckmanuals.com/home/brain\,-spinal-cord\,-and-nerve-disorders/movement-disorders/coordination-disorders]
is_a: SYMP:0000079 ! coordination symptom

[Term]
id: SYMP:0000305
name: impaired gag reflex
is_a: SYMP:0000249 ! reflex symptom

[Term]
id: SYMP:0000306
name: inability to feed
def: "A feeding difficulties and mismanagement that is characterized by a lack of feeding capacity." [url:https\://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851259/]
is_a: SYMP:0000522 ! feeding difficulties and mismanagement

[Term]
id: SYMP:0000307
name: inibility to stand
is_a: SYMP:0000329 ! motor weakness

[Term]
id: SYMP:0000308
name: inability to swallow
is_a: SYMP:0000385 ! throat symptom

[Term]
id: SYMP:0000309
name: loss of appetite
def: "An alteration of appetite that is characterized by a loss of desire to eat, i.e. no desire to eat." [url:https\://www.merckmanuals.com/home/digestive-disorders/symptoms-of-digestive-disorders/loss-of-appetite]
synonym: "inappetence" EXACT []
synonym: "lack of appetite" EXACT []
is_a: SYMP:0000244 ! alteration of appetite

[Term]
id: SYMP:0000310
name: inflamed eyes
is_a: SYMP:0019163 ! eye symptom

[Term]
id: SYMP:0000311
name: intestinal hypermotility
is_a: SYMP:0000459 ! digestive system symptom

[Term]
id: SYMP:0000312
name: joint symptom
is_a: SYMP:0000891 ! musculoskeletal system symptom

[Term]
id: SYMP:0000313
name: joint inflammation
is_a: SYMP:0000312 ! joint symptom

[Term]
id: SYMP:0000314
name: keratitis
comment: doid/symp duplicate
synonym: "corneitis" EXACT []
synonym: "inflammation of the cornea of the eye" EXACT []
is_a: SYMP:0000239 ! cornea symptom

[Term]
id: SYMP:0000315
name: lateroventral deviation of the head
is_a: SYMP:0000387 ! head symptom

[Term]
id: SYMP:0000316
name: leg cramp
is_a: SYMP:0000093 ! muscle cramp

[Term]
id: SYMP:0000317
name: obsolete leukopenia
comment: doid/symp duplicate - reviewed 10/2022 & determined to be a disease
synonym: "low white blood cell count" EXACT []
is_obsolete: true

[Term]
id: SYMP:0000318
name: loss of balance
def: "A  balance symptom that is characterized by an inability to stay upright and move confidently.  Loss of balance may be due to problems in the inner ear, the brain, or the heart. Aging, infections, head injury, certain medicines, and problems with blood circulation may also cause balance problems." [url:https\://medlineplus.gov/balanceproblems.html, url:https\://www.nidcd.nih.gov/health/balance-disorders]
is_a: SYMP:0020045 ! balance symptom

[Term]
id: SYMP:0000319
name: loss of tendon reflex
is_a: SYMP:0000249 ! reflex symptom

[Term]
id: SYMP:0000320
name: vision symptom
is_a: SYMP:0019163 ! eye symptom

[Term]
id: SYMP:0000321
name: loss of vision
is_a: SYMP:0000320 ! vision symptom

[Term]
id: SYMP:0000322
name: low birth weight
def: "A weight symptom that is characterized by an infant weighing 5.5 pounds (2500 grams) or less at birth.  Low birth weight may occur with premature birth, or due to smoking cigarettes, secondhand tobacco smoke exposure, drinking alcohol, and taking certain drugs during pregnancy." [url:https\://www.cancer.gov/publications/dictionaries/cancer-terms/def/low-birth-weight]
is_a: SYMP:0020012 ! weight symptom

[Term]
id: SYMP:0000323
name: melena
def: "A feces and droppings symptom that is characterized by the passage of dark tarry stools containing decomposing blood that is usually an indication of bleeding in the upper part of the alimentary canal and especially the esophagus, stomach, and duodenum." [url:http\://www.merriam-webster.com/medlineplus/melena]
synonym: "melaena" EXACT []
is_a: SYMP:0000146 ! feces and droppings symptom

[Term]
id: SYMP:0000324
name: bronchitis
def: "A respiratory system and chest symptom that is characterized by an acute or chronic inflammation of the bronchial tubes." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=bronchitis]
comment: doid/symp duplicate
is_a: SYMP:0000514 ! respiratory system and chest symptom

[Term]
id: SYMP:0000325
name: mild bronchitis
is_a: SYMP:0000324 ! bronchitis

[Term]
id: SYMP:0000326
name: mild hypotension
is_a: SYMP:0000059 ! hypotension

[Term]
id: SYMP:0000327
name: tetanic convulsion
def: "A convulsion that is characterized by a tonic spasm (prolonged contraction of the muscles), without loss of consciousness and often associated with hypocalcemia." [url:https\://medical-dictionary.thefreedictionary.com/tetanic]
synonym: "tetanic convulsions" EXACT []
is_a: SYMP:0000596 ! convulsion

[Term]
id: SYMP:0000328
name: mild tetanic convulsion
def: "A tetanic convulsion that is not intense (not severe)." [url:https\://www.macmillandictionary.com/us/dictionary/american/mild_1]
is_a: SYMP:0000327 ! tetanic convulsion

[Term]
id: SYMP:0000329
name: motor weakness
is_a: SYMP:0000891 ! musculoskeletal system symptom

[Term]
id: SYMP:0000330
name: mouth sore
is_a: SYMP:0000386 ! mouth symptom

[Term]
id: SYMP:0000331
name: muscle ache
def: "A pain that is characterized by a continuous or prolonged dull pain." [url:https\://www.merriam-webster.com/dictionary/ache]
is_a: SYMP:0019161 ! muscle pain

[Term]
id: SYMP:0000332
name: muscle soreness
is_a: SYMP:0000183 ! muscle symptom

[Term]
id: SYMP:0000333
name: muscle tenderness
is_a: SYMP:0000183 ! muscle symptom

[Term]
id: SYMP:0000334
name: muscle necrosis
is_a: SYMP:0000183 ! muscle symptom
is_a: SYMP:0020062 ! soft tissue necrosis

[Term]
id: SYMP:0000335
name: neck weakness
is_a: SYMP:0000384 ! neck symptom

[Term]
id: SYMP:0000336
name: neurological dysfunction
is_a: SYMP:0000480 ! nervous system symptom

[Term]
id: SYMP:0000337
name: night sweats
synonym: "sleep hyperhidrosis" EXACT []
is_a: SYMP:0000566 ! sleep disturbance

[Term]
id: SYMP:0000338
name: nystagmus
synonym: "rapid involuntary rhythmic eye movement" EXACT []
is_a: SYMP:0019163 ! eye symptom

[Term]
id: SYMP:0000339
name: occasional diplopia
is_a: SYMP:0000258 ! double vision

[Term]
id: SYMP:0000340
name: limb edema
def: "An adema that is characterized by an abnormal excess accumulation of serous fluid in connective tissue of the limbs." [url:https\://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536506/]
synonym: "limb oedema" EXACT []
synonym: "oedema of the limbs" EXACT []
is_a: SYMP:0000538 ! edema

[Term]
id: SYMP:0000341
name: obsolete ophthalmoplegia
comment: doid/symp duplicate - reviewed 10/2022 & determined to be a disease
synonym: "extraocular muscle paralysis" EXACT []
synonym: "eye movement paralysis" EXACT []
is_obsolete: true

[Term]
id: SYMP:0000342
name: slurred speech
is_a: SYMP:0000386 ! mouth symptom

[Term]
id: SYMP:0000343
name: painful lymph glands
def: "A pain that is characterized by a pain situated, or occurring, in the lymph gland (lymph node). Pain is often associated with swelling of the gland, which is a sign that one's body is fighting an infection." [url:https\://en.wikipedia.org/wiki/Lymph_node, url:https\://www.nhs.uk/conditions/swollen-glands/, url:https\://www.webmd.com/a-to-z-guides/swollen-glands]
synonym: "painful lymph nodes" EXACT []
is_a: SYMP:0000099 ! pain

[Term]
id: SYMP:0000344
name: palpebral edema
def: "An adema that is characterized by an abnormal excess accumulation of serous fluid in connective tissue of the eyelids." [url:https\://scopeheal.com/palpebral-edema/]
synonym: "edema of the eyelid" EXACT []
is_a: SYMP:0000538 ! edema

[Term]
id: SYMP:0000345
name: panting respiration
def: "A respiratory abnormality that is characterized by short, shallow, and rapid breathing." [url:https\://medical-dictionary.thefreedictionary.com/panting]
is_a: SYMP:0000598 ! respiratory abnormality

[Term]
id: SYMP:0000346
name: papule
def: "A skin and integumentary tissue symptom that is characterized by a small solid usually conical elevation of the skin caused by inflammation, accumulated secretion, or hypertrophy of tissue elements." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=papule]
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000347
name: lip paralysis
synonym: "paralysed lips" EXACT []
is_a: SYMP:0000030 ! paralysis

[Term]
id: SYMP:0000348
name: throat muscle paralysis
is_a: SYMP:0000030 ! paralysis

[Term]
id: SYMP:0000349
name: paraplegia
def: "A paralysis that is characterized by a complete, or partial, loss of function of the lower half of the body with involvement of both legs that is usually due to injury or disease of the spinal cord in the thoracic or lumbar region." [url:https\://www.merriam-webster.com/dictionary/paraplegia]
comment: doid/symp duplicate
is_a: SYMP:0000030 ! paralysis

[Term]
id: SYMP:0000350
name: parotid abscess
is_a: SYMP:0000205 ! salivary gland symptom

[Term]
id: SYMP:0000351
name: obsolete partial paralysis of the limbs
is_obsolete: true

[Term]
id: SYMP:0000352
name: peripheral muscle weakness
is_a: SYMP:0000094 ! muscle weakness

[Term]
id: SYMP:0000353
name: phlegm
def: "A respiratory system and chest symptom that is characterized by a viscid mucus secreted in abnormal quantity in the respiratory passages." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=phlegm]
is_a: SYMP:0000514 ! respiratory system and chest symptom

[Term]
id: SYMP:0000354
name: pneumonitis
def: "A respiratory system and chest symptom that is characterized by an inflammation of lung tissue. Pneumonia is one type of pneumonitis caused by an infection. Many other factors can cause pneumonitis, including breathing in animal dander, inhaling small food particles 'down the wrong pipe' and receiving radiation therapy to your chest." [url:http\://en.wikipedia.org/wiki/Pneumonitis]
synonym: "inflammation of lung tissue" EXACT []
is_a: SYMP:0000514 ! respiratory system and chest symptom

[Term]
id: SYMP:0000355
name: poor feeding
def: "A feeding difficulties and mismanagement that is characterized by an infant with little interest in feeding and it can also refer to an infant who is not feeding enough to receive the necessary nutrition required for adequate growth." [url:https\://www.healthline.com/health/poor-feeding-in-infants]
is_a: SYMP:0000522 ! feeding difficulties and mismanagement

[Term]
id: SYMP:0000356
name: phlebitis
comment: doid/symp duplicate
synonym: "inflammation of a vein" EXACT []
is_a: SYMP:0000528 ! cardiovascular system symptom

[Term]
id: SYMP:0000357
name: postphlebitic ulcer
is_a: SYMP:0000528 ! cardiovascular system symptom

[Term]
id: SYMP:0000358
name: premature labor
def: "A reproductive system symptom that is characterized by labor occurring before 37 full weeks of pregnancy." [url:http\://www.ehealthmd.com/library/amniocentesis/AMO_glossary.html]
is_a: SYMP:0000196 ! reproductive system symptom

[Term]
id: SYMP:0000359
name: profound weakness
is_a: SYMP:0000177 ! weakness

[Term]
id: SYMP:0000360
name: emaciation
def: "A wasting that is characterized by the state of being extremely thin as a result of an absence of body fat and very week as a result of muscle wasting; usually because of illness or extreme hunger." [url:https\://dictionary.cambridge.org/us/dictionary/english/emaciation, url:https\://en.wikipedia.org/wiki/Emaciation]
is_a: SYMP:0000174 ! wasting

[Term]
id: SYMP:0000361
name: progressive emaciation
def: "An emaciation that is characterized by an increase in scope or severity with time." [url:https\://www.rxlist.com/progressive/definition.htm]
is_a: SYMP:0000360 ! emaciation

[Term]
id: SYMP:0000362
name: progressive prostration
is_a: SYMP:0000116 ! prostration

[Term]
id: SYMP:0000363
name: progressive weakness
is_a: SYMP:0000177 ! weakness

[Term]
id: SYMP:0000364
name: prostate symptom
is_a: SYMP:0000196 ! reproductive system symptom

[Term]
id: SYMP:0000365
name: prostatic abscess
def: "A prostate symptom that is characterized by a localized collection of purulent fluid within the prostate, often forming as a complication of acute bacterial prostatitis." [url:https\://www.ncbi.nlm.nih.gov/books/NBK551663/]
is_a: SYMP:0000364 ! prostate symptom

[Term]
id: SYMP:0000366
name: prostatic infection
def: "A prostate symptom that is characterized by inflammation of the prostate and surrounding area." [url:https\://www.healthline.com/health/prostate-infection#]
is_a: SYMP:0000364 ! prostate symptom

[Term]
id: SYMP:0000367
name: proteinuria
def: "A urinary system symptom characterized by the presence of excess protein in the urine." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=proteinuria]
comment: doid/symp duplicate
is_a: SYMP:0000486 ! urinary system symptom

[Term]
id: SYMP:0000368
name: proximal paralysis of arm and leg
is_a: SYMP:0000030 ! paralysis

[Term]
id: SYMP:0000369
name: ptosis
def: "Ptosis is a general symptom characterized by a sagging or prolapse of an organ or part." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=ptosis]
comment: doid/symp duplicate - reviewed 10/2022, both DO & SYMP
synonym: "droopiness" EXACT []
is_a: SYMP:0000567 ! general symptom

[Term]
id: SYMP:0000370
name: renal abscess
def: "A urinary system symptom that is characterized by a pocket (a walled-off cavity) of pus that develops in the kidney tissue. It results from the migration of bacteria from another infection site on the body to the kidneys." [url:https\://www.uptodate.com/contents/renal-and-perinephric-abscess]
synonym: "kidney abscess" EXACT []
synonym: "perirenal abscess" EXACT []
is_a: SYMP:0000486 ! urinary system symptom

[Term]
id: SYMP:0000371
name: respiratory paralysis
def: "A paralysis that is characterized by a complete or severe weakness of the muscles of respiration." [url:https\://www.ncbi.nlm.nih.gov/mesh/68012133]
is_a: SYMP:0000030 ! paralysis

[Term]
id: SYMP:0000372
name: rhinorrhea
def: "A nose symptom that is characterized by an excessive secretion of mucous through the nose." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=Rhinorrhea]
synonym: "runny nose" EXACT []
is_a: SYMP:0000388 ! nose symptom

[Term]
id: SYMP:0000373
name: salivation
is_a: SYMP:0000205 ! salivary gland symptom

[Term]
id: SYMP:0000374
name: scrotal abscess
def: "A reproductive system symptom that is characterized by an abscess that is either superficial or intrascrotal.  Superficial scrotal abscess may occur from an infected hair follicle, infection of a scrotal laceration, or minor scrotal surgery.  Intrascrotal abscess most commonly arises from bacterial epididymitis, but may also be related to tuberculous infection of the epididymis, a testicular abscess that ruptures through the tunica albuginea, or drainage of appendicitis into scrotum through a patent processus vaginalis or as a result of extravasation of infected urine from the urethra in patients with a urethral stricture and neurogenic bladder using an external collection device." [url:https\://emedicine.medscape.com/article/1949750-overview]
is_a: SYMP:0000196 ! reproductive system symptom

[Term]
id: SYMP:0000375
name: severe abdominal cramp
is_a: SYMP:0000001 ! abdominal cramp

[Term]
id: SYMP:0000376
name: severe diarrhea
is_a: SYMP:0000570 ! diarrhea

[Term]
id: SYMP:0000377
name: obsolete mastitis
def: "A skin and integumentary tissue symptom that is characterized by an inflammation of the mammary gland or udder and usually caused by infection." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=mastitis]
comment: doid/symp duplicate - reviewed 10/2022 & determined to be a disease
synonym: "inflammation of mammary breast" EXACT []
synonym: "mammitis" EXACT []
is_obsolete: true
replaced_by: SYMP:0020053

[Term]
id: SYMP:0000378
name: obsolete severe mastitis
def: "A mastitis that is characterized by an increased intensity or severity of the condition." [url:https\://medical-dictionary.thefreedictionary.com/severe]
comment: reviewed 10/2022 & determined to be a disease
is_obsolete: true
replaced_by: SYMP:0020054

[Term]
id: SYMP:0000379
name: severe myalgia
def: "A muscle pain that is characterized by being severe in nature.  Myalgia may be acute in nature, stemming from overuse of a muscle group or viral infection.  It may also be chronic and caused by  metabolic myopathy, some nutritional deficiencies, and chronic fatigue syndrome." [url:https\://en.wikipedia.org/wiki/Myalgia]
is_a: SYMP:0019161 ! muscle pain

[Term]
id: SYMP:0000380
name: obsolete severe pneumonia
comment: reviewed 10/2022 & determined to be a disease
is_obsolete: true
replaced_by: SYMP:0020058

[Term]
id: SYMP:0000381
name: spleen abscess
is_a: SYMP:0000158 ! spleen symptom

[Term]
id: SYMP:0000382
name: staggering gait
is_a: SYMP:0000891 ! musculoskeletal system symptom

[Term]
id: SYMP:0000383
name: stiff neck
is_a: SYMP:0000384 ! neck symptom

[Term]
id: SYMP:0000384
name: neck symptom
synonym: "cervicalgia" EXACT []
is_a: SYMP:0000597 ! head and neck symptom

[Term]
id: SYMP:0000385
name: throat symptom
is_a: SYMP:0000597 ! head and neck symptom

[Term]
id: SYMP:0000386
name: mouth symptom
is_a: SYMP:0000387 ! head symptom

[Term]
id: SYMP:0000387
name: head symptom
is_a: SYMP:0000597 ! head and neck symptom

[Term]
id: SYMP:0000388
name: nose symptom
is_a: SYMP:0000387 ! head symptom

[Term]
id: SYMP:0000389
name: stupor
def: "An alteration of consciousness that is characterized by a lack of critical mental function and a level of consciousness, in which an affected person is almost entirely unresponsive and responds only to intense stimuli such as pain." [url:https\://en.wikipedia.org/wiki/Stupor]
is_a: SYMP:0000482 ! alteration of consciousness

[Term]
id: SYMP:0000390
name: thyroid symptom
is_a: SYMP:0000385 ! throat symptom

[Term]
id: SYMP:0000391
name: thyroid abscesses
is_a: SYMP:0000390 ! thyroid symptom

[Term]
id: SYMP:0000392
name: ear symptom
is_a: SYMP:0000387 ! head symptom

[Term]
id: SYMP:0000393
name: tinnitus
synonym: "sensation of noise" EXACT []
is_a: SYMP:0000392 ! ear symptom

[Term]
id: SYMP:0000394
name: muscle twitching
is_a: SYMP:0000183 ! muscle symptom

[Term]
id: SYMP:0000395
name: facial muscle twitching
is_a: SYMP:0000394 ! muscle twitching

[Term]
id: SYMP:0000396
name: mydriasis
synonym: "excessive pupil dilation" EXACT []
synonym: "prolonged pupil dilation" EXACT []
is_a: SYMP:0000254 ! dilated pupil

[Term]
id: SYMP:0000397
name: unreactive mydriasis
is_a: SYMP:0000396 ! mydriasis

[Term]
id: SYMP:0000398
name: vaginal discharge
def: "A reproductive system symptom that is characterized by fluid made by glands inside the vagina and cervix carrying away dead cells and bacteria. While it is normal for odor and color to vary, vaginal itching or burning may be indicative of an infection." [url:https\://www.merckmanuals.com/professional/gynecology-and-obstetrics/symptoms-of-gynecologic-disorders/vaginal-bleeding, url:https\://www.webmd.com/women/guide/vaginal-discharge-whats-abnormal]
comment: doid/symp duplicate
is_a: SYMP:0000196 ! reproductive system symptom

[Term]
id: SYMP:0000399
name: vertigo
def: "A dizziness that is characterized by a specific type of dizziness, a major symptom of a balance disorder. It is the sensation of spinning or swaying while the body is stationary with respect to the surroundings." [url:http\://en.wikipedia.org/wiki/Vertigo_%28medical%29]
is_a: SYMP:0000610 ! dizziness

[Term]
id: SYMP:0000400
name: weak cry
is_a: SYMP:0000411 ! infant symptom

[Term]
id: SYMP:0000401
name: wobble
is_a: SYMP:0000479 ! abnormality of gait

[Term]
id: SYMP:0000402
name: cachexia
def: "A nutrition, metabolism, and development symptom that is characterized by a general physical wasting and malnutrition usually associated with chronic disease." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=cachexia]
synonym: "general physical wasting and malnutrition" EXACT []
is_a: SYMP:0000473 ! nutrition, metabolism, and development symptom

[Term]
id: SYMP:0000403
name: weight gain
alt_id: SYMP:0020015
def: "A weight symptom that is characterized by an increase in body weight. This can involve an increase in muscle mass, fat deposits, excess fluids such as water or other factors." [url:https\://en.wikipedia.org/wiki/Weight_gain#]
synonym: "gain of weight" EXACT []
is_a: SYMP:0020012 ! weight symptom

[Term]
id: SYMP:0000404
name: dyspareunia
synonym: "difficult sexual intercourse" EXACT []
synonym: "painful sexual intercourse" EXACT []
is_a: SYMP:0000099 ! pain

[Term]
id: SYMP:0000405
name: vaginismus
def: "A reproductive system symptom that is characterized by a painful spasmodic contraction of the vagina." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=vaginismus]
synonym: "painful spasmodic vagina contractions" EXACT []
is_a: SYMP:0000196 ! reproductive system symptom

[Term]
id: SYMP:0000406
name: bruise
def: "A skin and integumentary tissue symptom that is characterized by an injury transmitted through unbroken skin to underlying tissue causing rupture of small blood vessels and escape of blood into the tissue with resulting discoloration." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=bruise]
synonym: "bruises" EXACT []
synonym: "bruising" EXACT []
synonym: "contusion" EXACT []
synonym: "ecchymosis" EXACT []
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000407
name: syncope
alt_id: SYMP:0000445
def: "An alteration of consciousness that is characterized by a loss of consciousness resulting from insufficient blood flow to the brain." [url:https\://en.wikipedia.org/wiki/Syncope_(medicine), url:https\://www.merriam-webster.com/dictionary/fainting, url:https\://www.merriam-webster.com/dictionary/syncope]
synonym: "faint" EXACT []
synonym: "fainting" EXACT []
synonym: "loss of consciousness due to insuffiecient blood flow to the brain" EXACT []
is_a: SYMP:0000482 ! alteration of consciousness

[Term]
id: SYMP:0000408
name: cataplexy
def: "Cataplexy is a muscle symptom characterized by a sudden loss of muscle control with retention of clear consciousness that follows a strong emotional stimulus (as elation, surprise, or anger) and is a characteristic symptom of narcolepsy." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=cataplexy]
is_a: SYMP:0000183 ! muscle symptom

[Term]
id: SYMP:0000409
name: hyperthermia
def: "A high fever that is characterized by an exceptionally high fever especially when induced artificially for therapeutic purposes." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=hyperthermia]
is_a: SYMP:0000882 ! high fever

[Term]
id: SYMP:0000410
name: neurological and physiological symptom
is_a: SYMP:0000462 ! symptom

[Term]
id: SYMP:0000411
name: infant symptom
is_a: SYMP:0000567 ! general symptom

[Term]
id: SYMP:0000412
name: anxiety
def: "A neurological and physiological symptom that is characterized by a painful or apprehensive uneasiness of mind usually over an impending or anticipated ill." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=anxiety]
is_a: SYMP:0000410 ! neurological and physiological symptom

[Term]
id: SYMP:0000413
name: catatonia
def: "A neurological and physiological symptom that is characterized by a marked psychomotor disturbance that may involve stupor or mutism, negativism, rigidity, purposeless excitement, echolalia, echopraxia, and inappropriate or bizarre posturing and is associated with various medical conditions (as schizophrenia and mood disorders)." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=catatonia]
is_a: SYMP:0000410 ! neurological and physiological symptom

[Term]
id: SYMP:0000414
name: dysarthria
def: "A neurological and physiological symptom that is characterized by a difficulty in articulating words due to disease of the central nervous system." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=dysarthria]
is_a: SYMP:0000410 ! neurological and physiological symptom

[Term]
id: SYMP:0000415
name: amaurosis fugax
is_a: SYMP:0000416 ! amaurosis

[Term]
id: SYMP:0000416
name: amaurosis
is_a: SYMP:0000321 ! loss of vision

[Term]
id: SYMP:0000417
name: pupil symptom
is_a: SYMP:0019163 ! eye symptom

[Term]
id: SYMP:0000418
name: contracted pupil
is_a: SYMP:0000417 ! pupil symptom

[Term]
id: SYMP:0000419
name: miosis
is_a: SYMP:0000418 ! contracted pupil

[Term]
id: SYMP:0000420
name: bloating
def: "Bloating is a digestive system symptom involving the accumulation of gas in the digestive tract and resulting in abdominal distension." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=bloating]
is_a: SYMP:0000459 ! digestive system symptom

[Term]
id: SYMP:0000421
name: hematochezia
def: "hematochezia is a feces and droppings symptom characterized by the passage of fresh blood per anus, usually in or with stools." [url:https\://www.ncbi.nlm.nih.gov/books/NBK411/#A2794]
is_a: SYMP:0000146 ! feces and droppings symptom

[Term]
id: SYMP:0000422
name: dyspepsia
def: "Dyspepsia is a digestive system symptom referred to as indigestion resulting from an impairment to digestion caused by ulcer, gall bladder disease or inflamed colon. Related symptoms include weakness, loss of appetite, and depression." [url:http\://www.rootsweb.ancestry.com/~vapage2/deathcauses.htm]
comment: doid/symp duplicate
synonym: "indigestion" EXACT []
is_a: SYMP:0000459 ! digestive system symptom

[Term]
id: SYMP:0000423
name: pyrosis
alt_id: SYMP:0000439
def: "From synonym: Heartburn is a pain characterized by a painful burning feeling in your chest or throat that happens when stomach acid backs up into your esophagus." [url:https\://medlineplus.gov/heartburn.html]
synonym: "acid indigestion" EXACT []
synonym: "heartburn" EXACT []
is_a: SYMP:0000459 ! digestive system symptom

[Term]
id: SYMP:0000424
name: claudication
def: "A pain that is characterized by a leg pain in the calf, or thigh, which is caused by inadequate blood flow to the leg muscles and is brought on by leg exercise such as walking." [url:http\://www.nature.com/nrd/journal/v2/n1/glossary/nrd985_glossary.html, url:http\://www.vasculardoc.net/content/glossary.html]
synonym: "blockage of leg arteries" EXACT []
is_a: SYMP:0000099 ! pain

[Term]
id: SYMP:0000425
name: reticulocytosis
is_a: SYMP:0019139 ! hemic system symptom

[Term]
id: SYMP:0000426
name: macrocytosis
is_a: SYMP:0019139 ! hemic system symptom

[Term]
id: SYMP:0000427
name: obsolete impotence
def: "A reproductive system symptom that is characterized by an abnormal physical or psychological state of a male characterized by inability to copulate because of failure to have, or maintain, an erection." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=impotence]
comment: doid/symp duplicate - reviewed 10/2022 & determined to be a disease
synonym: "erectile dysfunction" EXACT []
is_obsolete: true

[Term]
id: SYMP:0000428
name: hypoventilation
def: "A respiratory abnormality that is characterized by a deficient ventilation of the lungs that results in reduction in the oxygen content or increase in the carbon dioxide content of the blood or both." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=hypoventilation]
is_a: SYMP:0000598 ! respiratory abnormality

[Term]
id: SYMP:0000429
name: bradypnea
def: "A respiratory abnormality that is characterized by abnormally slow breathing." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=bradypnea]
synonym: "abnormally slow breathing" EXACT []
is_a: SYMP:0000598 ! respiratory abnormality

[Term]
id: SYMP:0000430
name: pleuritic chest pain
def: "A chest pain that is characterized by an inflammation of the pleural cavity with a sharp pain resulting from the exansion of the lungs as the inflammed pleural layers rub against each other." [url:http\://en.wikipedia.org/wiki/Pleuritic_chest_pain, url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=pleurisy]
is_a: SYMP:0000576 ! chest pain

[Term]
id: SYMP:0000431
name: sputum
def: "A respiratory system and chest symptom that is characterized by matter discharged from the air passages in diseases of the lungs, bronchi, or upper respiratory tract that contains mucus and often pus, blood, fibrin, or bacterial products." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=sputum]
synonym: "sputum production" EXACT []
is_a: SYMP:0000514 ! respiratory system and chest symptom

[Term]
id: SYMP:0000432
name: itching
def: "A skin and integumentary tissue symptom that is characterized by an uneasy irritating sensation in the upper surface of the skin usually held to result from mild stimulation of pain receptors." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=itching]
synonym: "pruritus" EXACT []
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000433
name: anasarca
def: "Anasarca is a edema characterized as generalized edema with accumulation of serum in the connective tissue." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=anasarca]
synonym: "generalized edema" EXACT []
is_a: SYMP:0000538 ! edema

[Term]
id: SYMP:0000434
name: urticaria
def: "A skin and integumentary tissue symptom that is characterized by raised red skin wheals (welts) commonly caused by an allergic reaction with wheals that may vary in size from about 5 mm (0.2 inches) in diameter to the size of a dinner plate that are described as severely itchy a stingnig or burning sensation, and having a pale border." [url:http\://en.wikipedia.org/wiki/Urticaria]
comment: doid/symp duplicate
synonym: "hives" EXACT []
synonym: "nettle rash" EXACT []
synonym: "uredo" EXACT []
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000435
name: paresthesia
def: "A skin and integumentary tissue symptom that is characterized by a sensation of pricking, tingling, or creeping on the skin having no objective cause and usually associated with injury or irritation of a sensory nerve or nerve root." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=paresthesia]
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000436
name: abnormal vaginal bleeding
def: "A reproductive system symptom that is characterized by bleeding from the uterus that is longer than usual or that occurs at an irregular time. Bleeding may be heavier or lighter than usual and occur often or randomly." [url:https\://medlineplus.gov/ency/article/000903.htm]
synonym: "abnormal menstruation" EXACT []
is_a: SYMP:0000196 ! reproductive system symptom

[Term]
id: SYMP:0000437
name: earache
is_a: SYMP:0000099 ! pain

[Term]
id: SYMP:0000438
name: toothache
def: "A pain that is characterized by a pain in, or about, a tooth or teeth." [url:https\://www.merriam-webster.com/dictionary/toothache]
is_a: SYMP:0000099 ! pain

[Term]
id: SYMP:0000439
name: obsolete heartburn
def: "Heartburn is a pain characterized by a painful burning feeling in your chest or throat that happens when stomach acid backs up into your esophagus." [url:http\://www.nlm.nih.gov/medlineplus/heartburn.html]
synonym: "acid indigestion" EXACT []
is_obsolete: true
replaced_by: SYMP:0000423

[Term]
id: SYMP:0000440
name: hair loss
def: "A hair symptom that is characterized by the stopping of hair growth (regeneration), which may be a result of hereditary hair loss, immune system overreacts, drugs and treatments, harsh hair-care products, and other factors." [url:https\://www.aad.org/public/diseases/hair-loss/insider/shedding]
is_a: SYMP:0020040 ! hair symptom

[Term]
id: SYMP:0000441
name: elbow pain
def: "A joint pain that is characterized by a pain situated, or occurring, in or around the elbow." [url:https\://medlineplus.gov/ency/article/003172.htm]
is_a: SYMP:0000064 ! joint pain

[Term]
id: SYMP:0000442
name: knee pain
def: "A joint pain that is characterized by a pain situated, or occurring, in or around the knee." [url:https\://medlineplus.gov/ency/article/003187.htm]
is_a: SYMP:0000064 ! joint pain

[Term]
id: SYMP:0000443
name: shoulder pain
def: "A joint pain that is characterized by a pain situated, or occurring, in or around the shoulder." [url:https\://medlineplus.gov/ency/article/003171.htm]
is_a: SYMP:0000064 ! joint pain

[Term]
id: SYMP:0000444
name: nail discoloration
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000445
name: obsolete faint
def: "Faint is a alteration of consciousness characterized by a loss of consciousness because of a temporary decrease in the blood supply to the brain." [url:http\://www.merriam-webster.com/dictionary/fainting]
synonym: "fainting" EXACT []
synonym: "syncope" EXACT []
is_obsolete: true
replaced_by: SYMP:0000407

[Term]
id: SYMP:0000446
name: bloodshot eye
synonym: "red eye" EXACT []
synonym: "redness of eye" EXACT []
is_a: SYMP:0019163 ! eye symptom

[Term]
id: SYMP:0000447
name: bloody sputum
def: "A sputum that is characterized by blood or bloody mucus discharged from the air passages caused by common forms of infection in the lungs and airways, such as acute bronchitis or pneumonia. Bloody sputum can also come from cancer of the lung." [url:http\://www.medicinenet.com/symptoms_and_signs/article.htm, url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=sputum]
comment: Bloody sputum (spitting up blood or bloody mucus) can come from common forms of infection in the lungs and airways, such as acute bronchitis or pneumonia. Bloody sputum can also come from cancer of the lung.
is_a: SYMP:0000431 ! sputum

[Term]
id: SYMP:0000448
name: epistaxis
def: "A nose symptom that involves a is loss of blood from the tissue lining the nose." [url:http\://www.nlm.nih.gov/medlineplus/ency/article/003106.htm]
synonym: "nosebleed" EXACT []
xref: ICD9CM_2005:784.7
xref: UMLS_CUI:C0014591
xref: UMLS_ICD9CM_2005_AUI:A0055387
is_a: SYMP:0000388 ! nose symptom

[Term]
id: SYMP:0000449
name: cardiogenic shock
xref: ICD9CM_2005:785.51
xref: UMLS_CUI:C0036980
xref: UMLS_ICD9CM_2005_AUI:A0243814
is_a: SYMP:0000450 ! shock

[Term]
id: SYMP:0000450
name: shock
def: "A cardiovascular system symptom that is characterized as a state of profound depression of the vital processes of the body that is characterized by pallor, rapid but weak pulse, rapid and shallow respiration, reduced total blood volume, and low blood pressure and that is caused usually by severe especially crushing injuries, hemorrhage, burns, or major surgery." [url:http\://www.merriam-webster.com/medlineplus/shock]
xref: ICD9CM_2005:785.5
xref: UMLS_CUI:C0159051
xref: UMLS_ICD9CM_2005_AUI:A0284197
is_a: SYMP:0000528 ! cardiovascular system symptom

[Term]
id: SYMP:0000451
name: septic shock
xref: ICD9CM_2005:785.52
xref: UMLS_CUI:C0036983
is_a: SYMP:0000450 ! shock

[Term]
id: SYMP:0000452
name: abnormal sputum
xref: ICD9CM_2005:786.4
xref: UMLS_CUI:C0159054
xref: UMLS_ICD9CM_2005_AUI:A0284206
is_a: SYMP:0000431 ! sputum

[Term]
id: SYMP:0000453
name: right upper quadrant abdominal rigidity
xref: ICD9CM_2005:789.41
xref: UMLS_CUI:C0375565
is_a: SYMP:0000454 ! abdominal rigidity

[Term]
id: SYMP:0000454
name: abdominal rigidity
xref: ICD9CM_2005:789.4
xref: ICD9CM_2005:789.40
xref: UMLS_CUI:C0159066
xref: UMLS_ICD9CM_2005_AUI:A0284272
xref: UMLS_ICD9CM_2005_AUI:A0637149
is_a: SYMP:0000461 ! abdominal symptom

[Term]
id: SYMP:0000455
name: abnormal weight gain
def: "A weight gain that is characterized as deviating from what is normal or usual, typically in a way that is undesirable or worrying." [url:https\://www.merriam-webster.com/dictionary/abnormal]
xref: ICD9CM_2005:783.1
xref: UMLS_CUI:C0332544
xref: UMLS_ICD9CM_2005_AUI:A0243789
is_a: SYMP:0000403 ! weight gain

[Term]
id: SYMP:0000456
name: left upper quadrant abdominal pain
def: "An abdominal pain that is characterized by occurring in the left upper quadrant abdominal pain of the abdomen that can be caused by a stomach ulcer, acute gastritis, a viral infection, or indigestion, or may be an issue with one's lungs." [url:https\://www.buoyhealth.com/learn/pain-upper-left-abdomen]
xref: ICD9CM_2005:789.02
xref: UMLS_CUI:C0238552
xref: UMLS_ICD9CM_2005_AUI:A0637133
is_a: SYMP:0000457 ! abdominal pain

[Term]
id: SYMP:0000457
name: abdominal pain
def: "A pain that is characterized by occurring in the abdomen, i.e. between the chest and groin." [url:https\://medlineplus.gov/ency/article/003120.htm]
xref: ICD9CM_2005:789.0
xref: ICD9CM_2005:789.00
xref: UMLS_CUI:C0000737
xref: UMLS_ICD9CM_2005_AUI:A0387333
xref: UMLS_ICD9CM_2005_AUI:A0637138
is_a: SYMP:0000099 ! pain

[Term]
id: SYMP:0000458
name: nausea
def: "Nausea is a digestive system symptom characterized by an uneasy or unsettled feeling in the stomach together with an urge to vomit." [url:http\://www.nlm.nih.gov/medlineplus/nauseaandvomiting.html]
xref: ICD9CM_2005:787.02
xref: UMLS_CUI:C0375548
xref: UMLS_ICD9CM_2005_AUI:A0750850
is_a: SYMP:0000459 ! digestive system symptom

[Term]
id: SYMP:0000459
name: digestive system symptom
xref: ICD9CM_2005:787
xref: UMLS_CUI:C0159058
xref: UMLS_ICD9CM_2005_AUI:A0284224
is_a: SYMP:0000462 ! symptom

[Term]
id: SYMP:0000460
name: hepatomegaly
synonym: "enlargement of the liver" EXACT []
xref: ICD9CM_2005:789.1
xref: UMLS_CUI:C0019209
xref: UMLS_ICD9CM_2005_AUI:A0067592
is_a: SYMP:0000180 ! liver symptom

[Term]
id: SYMP:0000461
name: abdominal symptom
xref: ICD9CM_2005:789
xref: ICD9CM_2005:789.9
xref: UMLS_CUI:C0159065
xref: UMLS_ICD9CM_2005_AUI:A0284267
xref: UMLS_ICD9CM_2005_AUI:A0284268
is_a: SYMP:0000462 ! symptom

[Term]
id: SYMP:0000462
name: symptom
def: "A symptom is a perceived change in function, sensation, loss, disturbance or appearance reported by a patient indicative of a disease." [url:https\://link.springer.com/chapter/10.1007/978-1-4615-4789-1_5, url:https\://www.merriam-webster.com/dictionary/symptom, url:https\://www.nature.com/subjects/signs-and-symptoms]

[Term]
id: SYMP:0000463
name: lack of normal physiological development
xref: ICD9CM_2005:783.40
xref: UMLS_CUI:C0878706
xref: UMLS_ICD9CM_2005_AUI:A1892807
is_a: SYMP:0000464 ! lack of expected normal physiological development in childhood

[Term]
id: SYMP:0000464
name: lack of expected normal physiological development in childhood
xref: ICD9CM_2005:783.4
xref: UMLS_CUI:C0878753
xref: UMLS_ICD9CM_2005_AUI:A1892806
is_a: SYMP:0000473 ! nutrition, metabolism, and development symptom

[Term]
id: SYMP:0000465
name: failure to thrive
def: "A lack of expected normal physiological development in childhood that is characterized by a decelerated or arrested physical growth (height and weight measurements fall below the third or fifth percentile, or a downward change in growth across two major growth percentiles) and is associated with abnormal growth and development." [url:https\://www.chop.edu/conditions-diseases/failure-thrive]
xref: ICD9CM_2005:783.41
xref: UMLS_CUI:C0015544
xref: UMLS_ICD9CM_2005_AUI:A0700791
is_a: SYMP:0000464 ! lack of expected normal physiological development in childhood

[Term]
id: SYMP:0000466
name: delayed milestones
def: "A lack of expected normal physiological development in childhood that is characterized by a failure for a child to reach a significant stage at the predicted age and may include walking or talking." [url:https\://en.wikipedia.org/wiki/Delayed_milestone]
synonym: "developmental delay" EXACT []
xref: ICD9CM_2005:783.42
xref: UMLS_CUI:C0476241
xref: UMLS_ICD9CM_2005_AUI:A1594577
is_a: SYMP:0000464 ! lack of expected normal physiological development in childhood

[Term]
id: SYMP:0000467
name: right lower quadrant abdominal rigidity
xref: ICD9CM_2005:789.43
xref: UMLS_CUI:C0375567
is_a: SYMP:0000454 ! abdominal rigidity

[Term]
id: SYMP:0000468
name: generalized abdominal rigidity
xref: ICD9CM_2005:789.47
xref: UMLS_CUI:C0375571
xref: UMLS_ICD9CM_2005_AUI:A0637142
is_a: SYMP:0000454 ! abdominal rigidity

[Term]
id: SYMP:0000469
name: epigastric abdominal rigidity
xref: ICD9CM_2005:789.46
xref: UMLS_CUI:C0375570
xref: UMLS_ICD9CM_2005_AUI:A0637141
is_a: SYMP:0000454 ! abdominal rigidity

[Term]
id: SYMP:0000470
name: left upper quadrant abdominal rigidity
xref: ICD9CM_2005:789.42
xref: UMLS_CUI:C0375566
xref: UMLS_ICD9CM_2005_AUI:A0637144
is_a: SYMP:0000454 ! abdominal rigidity

[Term]
id: SYMP:0000471
name: multiple sites abdominal rigidity
xref: ICD9CM_2005:789.49
xref: UMLS_CUI:C0375572
xref: UMLS_ICD9CM_2005_AUI:A0637145
is_a: SYMP:0000454 ! abdominal rigidity

[Term]
id: SYMP:0000472
name: early satiety
def: "A nutrition, metabolism, and development symptom that is characterized by a feeling of being full after a few bites of food, or before you finish a normal-sized meal." [url:https\://www.healthline.com/health/satiety-early]
xref: ICD9CM_2005:780.94
xref: UMLS_CUI:C0239233
xref: UMLS_ICD9CM_2005_AUI:A2797496
is_a: SYMP:0000473 ! nutrition, metabolism, and development symptom

[Term]
id: SYMP:0000473
name: nutrition, metabolism, and development symptom
xref: ICD9CM_2005:783
xref: UMLS_CUI:C0159041
xref: UMLS_ICD9CM_2005_AUI:A0284163
is_a: SYMP:0000462 ! symptom

[Term]
id: SYMP:0000474
name: obsolete abnormal loss of weight and underweight
xref: ICD9CM_2005:783.2
xref: UMLS_CUI:C0878752
xref: UMLS_ICD9CM_2005_AUI:A1892727
is_obsolete: true

[Term]
id: SYMP:0000475
name: underweight
def: "A weight symptom that is characterized by weighing less than the normal amount for one's age, height, and build." [url:https\://www.merriam-webster.com/dictionary/underweight]
xref: ICD9CM_2005:783.22
xref: UMLS_CUI:C0041667
xref: UMLS_ICD9CM_2005_AUI:A0468826
is_a: SYMP:0020012 ! weight symptom

[Term]
id: SYMP:0000476
name: obsolete loss of weight
comment: This term has been replaced by weight loss.
synonym: "weight loss" EXACT []
xref: ICD9CM_2005:783.21
xref: UMLS_CUI:C0043096
xref: UMLS_ICD9CM_2005_AUI:A1605347
is_obsolete: true
replaced_by: SYMP:0000178

[Term]
id: SYMP:0000477
name: epigastric abdominal swelling
xref: ICD9CM_2005:789.36
xref: UMLS_CUI:C0375562
xref: UMLS_ICD9CM_2005_AUI:A0637121
is_a: SYMP:0000478 ! abdominal swelling

[Term]
id: SYMP:0000478
name: abdominal swelling
xref: ICD9CM_2005:789.3
xref: UMLS_CUI:C0476310
xref: UMLS_ICD9CM_2005_AUI:A0243858
is_a: SYMP:0000461 ! abdominal symptom

[Term]
id: SYMP:0000479
name: abnormality of gait
def: "Abnormality of gait is a nervous system and musculoskeletal system symptom characterized by a difficulty in the manner of walking or moving on foot." [url:http\://www.merriam-webster.com/dictionary/gait]
xref: ICD9CM_2005:781.2
xref: UMLS_CUI:C0575081
xref: UMLS_ICD9CM_2005_AUI:A0243767
is_a: SYMP:0000891 ! musculoskeletal system symptom

[Term]
id: SYMP:0000480
name: nervous system symptom
xref: ICD9CM_2005:781
xref: UMLS_CUI:C0159033
xref: UMLS_ICD9CM_2005_AUI:A0284131
is_a: SYMP:0000462 ! symptom

[Term]
id: SYMP:0000481
name: persistent vegetative state
def: "An alteration of consciousness that is characterized by an individual with severe brain damage being in a state of partial arousal rather than true awareness. After four weeks in a vegetative state, the patient is classified as being in a persistent vegetative state. After three months in the US and six months in the UK, the diagnosis is classified as a permanent vegetative state after a non-traumatic brain injury, or, one year after a traumatic injury." [url:https\://en.wikipedia.org/wiki/Persistent_vegetative_state]
xref: ICD9CM_2005:780.03
xref: UMLS_CUI:C0242670
xref: UMLS_ICD9CM_2005_AUI:A0446160
is_a: SYMP:0000482 ! alteration of consciousness

[Term]
id: SYMP:0000482
name: alteration of consciousness
def: "A neurological and physiological symptom that is characterized by any condition which is significantly different from a normal waking state." [url:https\://en.wikipedia.org/wiki/Altered_state_of_consciousness]
xref: ICD9CM_2005:780.0
xref: UMLS_CUI:C0234428
xref: UMLS_ICD9CM_2005_AUI:A0389211
is_a: SYMP:0000410 ! neurological and physiological symptom

[Term]
id: SYMP:0000483
name: left lower quadrant abdominal tenderness
xref: ICD9CM_2005:789.64
xref: UMLS_CUI:C0238565
xref: UMLS_ICD9CM_2005_AUI:A0637155
is_a: SYMP:0000484 ! abdominal tenderness

[Term]
id: SYMP:0000484
name: abdominal tenderness
xref: ICD9CM_2005:789.6
xref: ICD9CM_2005:789.60
xref: UMLS_CUI:C0232498
xref: UMLS_ICD9CM_2005_AUI:A0387353
xref: UMLS_ICD9CM_2005_AUI:A0637161
is_a: SYMP:0000461 ! abdominal symptom

[Term]
id: SYMP:0000485
name: dysuria
def: "A urinary system symptom that is characterized by the difficult, or painful, discharge of urine." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=dysuria]
synonym: "difficult urine discharge" EXACT []
synonym: "painful urine discharge" EXACT []
xref: ICD9CM_2005:788.1
xref: UMLS_CUI:C0013428
xref: UMLS_ICD9CM_2005_AUI:A0004041
is_a: SYMP:0000486 ! urinary system symptom

[Term]
id: SYMP:0000486
name: urinary system symptom
xref: ICD9CM_2005:788
xref: UMLS_CUI:C0476293
xref: UMLS_ICD9CM_2005_AUI:A0284245
is_a: SYMP:0000462 ! symptom

[Term]
id: SYMP:0000487
name: rash
def: "A skin and integumentary tissue symptom that is characterized by an eruption on the body typically with little or no elevation above the surface." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=rash]
synonym: "erythema" EXACT []
synonym: "rubor" EXACT []
synonym: "skin eruption" EXACT []
synonym: "skin rash" EXACT []
synonym: "skin redness" EXACT []
xref: ICD9CM_2005:782.1
xref: UMLS_CUI:C0015230
xref: UMLS_ICD9CM_2005_AUI:A0243780
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000488
name: skin and integumentary tissue symptom
def: "A skin and integumentary tissue symptom that is characterized by the outer layer of the skin starting to replace itself. Often, this happens when skin is damaged, either by disease or injury." [url:https\://www.medicinenet.com/peeling_skin/symptoms.htm, url:https\://www.webmd.com/skin-problems-and-treatments/what-know-about-peeling-skin-desquamation]
xref: ICD9CM_2005:782
xref: ICD9CM_2005:782.9
xref: UMLS_CUI:C0159037
xref: UMLS_ICD9CM_2005_AUI:A0284146
xref: UMLS_ICD9CM_2005_AUI:A0284161
is_a: SYMP:0000462 ! symptom

[Term]
id: SYMP:0000489
name: abnormal bowel sound
xref: ICD9CM_2005:787.5
xref: UMLS_CUI:C0159060
xref: UMLS_ICD9CM_2005_AUI:A0284234
is_a: SYMP:0000459 ! digestive system symptom

[Term]
id: SYMP:0000490
name: multiple sites abdominal tenderness
xref: ICD9CM_2005:789.69
xref: UMLS_CUI:C0375574
xref: UMLS_ICD9CM_2005_AUI:A0637157
is_a: SYMP:0000484 ! abdominal tenderness

[Term]
id: SYMP:0000491
name: continuous leakage of urine
xref: ICD9CM_2005:788.37
xref: UMLS_CUI:C0375553
xref: UMLS_ICD9CM_2005_AUI:A0679310
is_a: SYMP:0000492 ! urinary incontinence

[Term]
id: SYMP:0000492
name: urinary incontinence
def: "A urinary system symptom that is characterized by the an inability of the body to control the evacuative functions." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=incontinence]
synonym: "incontinence" EXACT []
xref: ICD9CM_2005:788.3
xref: ICD9CM_2005:788.30
xref: UMLS_CUI:C0042024
xref: UMLS_ICD9CM_2005_AUI:A0814766
xref: UMLS_ICD9CM_2005_AUI:A6994675
is_a: SYMP:0000486 ! urinary system symptom

[Term]
id: SYMP:0000493
name: dysphagia
synonym: "difficulty in swallowing" EXACT []
synonym: "difficulty swallowing" EXACT []
synonym: "impaired swallowing" EXACT []
xref: ICD9CM_2005:787.2
xref: UMLS_CUI:C0011168
xref: UMLS_ICD9CM_2005_AUI:A0052114
is_a: SYMP:0000385 ! throat symptom

[Term]
id: SYMP:0000494
name: renal colic
def: "A colic that is characterized by a severe pain produced by the passage of a calculus from the kidney through the ureter." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=renal%20colic]
xref: ICD9CM_2005:788.0
xref: UMLS_CUI:C0152169
xref: UMLS_ICD9CM_2005_AUI:A0265344
is_a: SYMP:0000235 ! colic

[Term]
id: SYMP:0000495
name: urethral discharge
def: "A urinary system symptom that is characterized by abnormal purulent or mucoid secretions from the penis or, rarely, the female urethra." [url:https\://accessmedicine.mhmedical.com/content.aspx?bookid=369&sectionid=39914779#\:~\:text=Urethral%20discharge%20is%20characterized%20by\,of%20leukorrhea%20and%20urethral%20inflammation]
xref: ICD9CM_2005:788.7
xref: UMLS_CUI:C0152447
xref: UMLS_ICD9CM_2005_AUI:A0266251
is_a: SYMP:0000486 ! urinary system symptom

[Term]
id: SYMP:0000496
name: epigastric abdominal tenderness
xref: ICD9CM_2005:789.66
xref: UMLS_CUI:C0239280
xref: UMLS_ICD9CM_2005_AUI:A0637153
is_a: SYMP:0000484 ! abdominal tenderness

[Term]
id: SYMP:0000497
name: periumbilic abdominal tenderness
xref: ICD9CM_2005:789.65
xref: UMLS_CUI:C0375573
xref: UMLS_ICD9CM_2005_AUI:A0637158
is_a: SYMP:0000484 ! abdominal tenderness

[Term]
id: SYMP:0000498
name: generalized abdominal tenderness
xref: ICD9CM_2005:789.67
xref: UMLS_CUI:C0302540
xref: UMLS_ICD9CM_2005_AUI:A0637154
is_a: SYMP:0000484 ! abdominal tenderness

[Term]
id: SYMP:0000499
name: right upper quadrant abdominal tenderness
xref: ICD9CM_2005:789.61
xref: UMLS_CUI:C0238571
is_a: SYMP:0000484 ! abdominal tenderness

[Term]
id: SYMP:0000500
name: right lower quadrant abdominal tenderness
xref: ICD9CM_2005:789.63
xref: UMLS_CUI:C0238570
is_a: SYMP:0000484 ! abdominal tenderness

[Term]
id: SYMP:0000501
name: left lower quadrant abdominal swelling
xref: ICD9CM_2005:789.34
xref: UMLS_CUI:C0375560
xref: UMLS_ICD9CM_2005_AUI:A0637123
is_a: SYMP:0000478 ! abdominal swelling

[Term]
id: SYMP:0000502
name: mixed incontinence (female) (male)
def: "A urinary incontinence that is characterized by urine leakage when you sneeze, cough, laugh, do jarring exercise, or lift something heavy. It is typically a combination of stress and urge incontinence." [url:https\://www.webmd.com/urinary-incontinence-oab/mixed-incontinence] {comment="url:https://www.health.harvard.edu/bladder-and-bowel/types-of-urinary-incontinence"}
xref: ICD9CM_2005:788.33
xref: UMLS_CUI:C0375550
xref: UMLS_ICD9CM_2005_AUI:A0745756
is_a: SYMP:0000492 ! urinary incontinence

[Term]
id: SYMP:0000503
name: adult failure to thrive
def: "A nutrition, metabolism, and development symptom that is characterized by a physical decline in health seen in older adults – typically those with multiple chronic medical conditions – resulting in decreased appetite and poor nutrition, weight loss, inactivity, often accompanied by dehydration, depression, decreasing functional ability, and impaired immune function." [url:https\://www.compassus.com/for-caregivers/what-is-adult-failure-to-thrive, url:https\://www.uptodate.com/contents/failure-to-thrive-in-older-adults-evaluation]
xref: ICD9CM_2005:783.7
xref: UMLS_CUI:C1268580
xref: UMLS_ICD9CM_2005_AUI:A1892736
is_a: SYMP:0000473 ! nutrition, metabolism, and development symptom

[Term]
id: SYMP:0000504
name: headache
def: "A pain that is characterized by a pain in the head." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=headache]
synonym: "cephalalgia" EXACT []
xref: ICD9CM_2005:784.0
xref: UMLS_CUI:C0018681
xref: UMLS_ICD9CM_2005_AUI:A0065994
is_a: SYMP:0000099 ! pain

[Term]
id: SYMP:0000505
name: throat pain
def: "A pain that is characterized by a painful throat due to inflammation of the fauces and pharynx." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=sore%20throat]
synonym: "sore throat" EXACT []
xref: ICD9CM_2005:784.1
xref: UMLS_CUI:C0242429
xref: UMLS_ICD9CM_2005_AUI:A0284175
is_a: SYMP:0000099 ! pain

[Term]
id: SYMP:0000506
name: hemorrhage from throat
xref: ICD9CM_2005:784.8
xref: UMLS_CUI:C0576995
xref: UMLS_ICD9CM_2005_AUI:A0284188
is_a: SYMP:0000385 ! throat symptom

[Term]
id: SYMP:0000507
name: head swelling
xref: ICD9CM_2005:784.2
xref: UMLS_CUI:C0159045
xref: UMLS_ICD9CM_2005_AUI:A0284180
is_a: SYMP:0000387 ! head symptom

[Term]
id: SYMP:0000508
name: aphasia
def: "A nervous system symptom that is characterized by a loss or impairment of the power to use or comprehend words usually resulting from brain damage." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=aphasia]
comment: doid/symp duplicate
synonym: "inability to comprehend language" EXACT []
xref: ICD9CM_2005:784.3
xref: UMLS_CUI:C0003537
xref: UMLS_ICD9CM_2005_AUI:A0025556
is_a: SYMP:0000480 ! nervous system symptom

[Term]
id: SYMP:0000509
name: flatulence
alt_id: SYMP:0000708
synonym: "gas" EXACT []
synonym: "gas production" EXACT []
xref: ICD9CM_2005:787.3
xref: UMLS_CUI:C0016205
xref: UMLS_ICD9CM_2005_AUI:A0243846
is_a: SYMP:0000459 ! digestive system symptom

[Term]
id: SYMP:0000510
name: pallor
def: "A skin and integumentary tissue symptom that is characterized by a deficiency of color especially of the face." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=pallor]
synonym: "paleness" EXACT []
xref: ICD9CM_2005:782.61
xref: UMLS_CUI:C0030232
xref: UMLS_ICD9CM_2005_AUI:A0096956
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000511
name: flushing
def: "A skin and integumentary tissue symptom that is characterized by a markedly red flush in a persons face and often other areas of the skin, from various physiological conditions. Flushing is generally distinguished, despite a close physiological relation between them, from blushing, which is milder, generally restricted to the face or cheeks, and generally assumed to reflect embarrassment. Flushing is also a cardinal symptom of carcinoid syndrome the syndrome that results from hormones (often serotonin or histamine) being secreted into systemic circulation." [url:http\://en.wikipedia.org/wiki/Flushing_%28physiology%29]
xref: ICD9CM_2005:782.62
xref: UMLS_CUI:C0016382
xref: UMLS_ICD9CM_2005_AUI:A0060138
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000512
name: male stress incontinence
def: "A stress incontinence that is characterized by a compromised external urinary sphincter muscle resulting from surgical or radiotherapeutic manipulation." [url:https\://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356867/]
xref: ICD9CM_2005:788.32
xref: UMLS_CUI:C0302505
xref: UMLS_ICD9CM_2005_AUI:A0800441
is_a: SYMP:0000853 ! stress incontinence

[Term]
id: SYMP:0000513
name: stridor
def: "An abnormal chest sound that is characterized by a harsh vibrating sound heard during respiration in cases of obstruction of the air passages." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=stridor]
xref: ICD9CM_2005:786.1
xref: UMLS_CUI:C0038450
xref: UMLS_ICD9CM_2005_AUI:A0120146
is_a: SYMP:0000587 ! abnormal chest sound

[Term]
id: SYMP:0000514
name: respiratory system and chest symptom
xref: ICD9CM_2005:786
xref: UMLS_CUI:C0476271
xref: UMLS_ICD9CM_2005_AUI:A0284200
is_a: SYMP:0000462 ! symptom

[Term]
id: SYMP:0000515
name: hiccough
def: "A respiratory system and chest symptom that is characterized by a spasmodic inhalation with closure of the glottis accompanied by a peculiar sound." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=hiccough]
xref: ICD9CM_2005:786.8
xref: UMLS_CUI:C0019521
xref: UMLS_ICD9CM_2005_AUI:A0421293
is_a: SYMP:0000514 ! respiratory system and chest symptom

[Term]
id: SYMP:0000516
name: lump in chest
xref: ICD9CM_2005:786.6
xref: UMLS_CUI:C0159055
xref: UMLS_ICD9CM_2005_AUI:A0284217
is_a: SYMP:0000514 ! respiratory system and chest symptom

[Term]
id: SYMP:0000517
name: hemoptysis
def: "A respiratory system and chest symptom that is characterized by an expectoration of blood from some part of the respiratory tract." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=hemoptysis]
synonym: "coughing up of blood" EXACT []
synonym: "expectoration of blood" EXACT []
synonym: "expectoration of blood-stained sputum" EXACT []
synonym: "haemoptysis" EXACT []
xref: ICD9CM_2005:786.3
xref: UMLS_CUI:C0019079
xref: UMLS_ICD9CM_2005_AUI:A0067232
is_a: SYMP:0000514 ! respiratory system and chest symptom

[Term]
id: SYMP:0000518
name: generalized abdominal pain
def: "An abdominal pain that is characterized by being diffuse or widespread and affecting or involving all of the abdomen." [url:https\://medical-dictionary.thefreedictionary.com/generalization, url:https\://www.merriam-webster.com/dictionary/generalized]
xref: ICD9CM_2005:789.07
xref: UMLS_CUI:C0344304
xref: UMLS_ICD9CM_2005_AUI:A0637131
is_a: SYMP:0000457 ! abdominal pain

[Term]
id: SYMP:0000519
name: abnormal feces
xref: ICD9CM_2005:787.7
xref: UMLS_CUI:C0162287
xref: UMLS_ICD9CM_2005_AUI:A0284238
is_a: SYMP:0000146 ! feces and droppings symptom

[Term]
id: SYMP:0000520
name: visible peristalsis
xref: ICD9CM_2005:787.4
xref: UMLS_CUI:C0159059
xref: UMLS_ICD9CM_2005_AUI:A0284228
is_a: SYMP:0000459 ! digestive system symptom

[Term]
id: SYMP:0000521
name: enlargement of lymph nodes
synonym: "swelling of lymph nodes" EXACT []
synonym: "swollen lymph glands" EXACT []
xref: ICD9CM_2005:785.6
xref: UMLS_CUI:C0497156
xref: UMLS_ICD9CM_2005_AUI:A0243823
is_a: SYMP:0019141 ! lymphatic system symptom

[Term]
id: SYMP:0000522
name: feeding difficulties and mismanagement
xref: ICD9CM_2005:783.3
xref: UMLS_CUI:C0699815
xref: UMLS_ICD9CM_2005_AUI:A0284167
is_a: SYMP:0000473 ! nutrition, metabolism, and development symptom

[Term]
id: SYMP:0000523
name: anorexia
def: "A nutrition, metabolism, and development symptom that is characterized by a loss of appetite especially when prolonged." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=anorexia]
xref: ICD9CM_2005:783.0
xref: UMLS_CUI:C0003123
xref: UMLS_ICD9CM_2005_AUI:A0024378
is_a: SYMP:0000473 ! nutrition, metabolism, and development symptom

[Term]
id: SYMP:0000524
name: polyphagia
def: "A nutrition, metabolism, and development symptom that is characterized by an excessive appetite or eating." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=polyphagia]
xref: ICD9CM_2005:783.6
xref: UMLS_CUI:C0020505
xref: UMLS_ICD9CM_2005_AUI:A0011381
is_a: SYMP:0000473 ! nutrition, metabolism, and development symptom

[Term]
id: SYMP:0000525
name: transient alteration of awareness
def: "An alteration of consciousness that is characterized by a brief (transient) episode of losing normal awareness or behavior." [url:https\://www.inst-neuro.com/services/epilepsy/transient-alteration-of-awareness/]
xref: ICD9CM_2005:780.02
xref: UMLS_CUI:C0221539
xref: UMLS_ICD9CM_2005_AUI:A0466980
is_a: SYMP:0000482 ! alteration of consciousness

[Term]
id: SYMP:0000526
name: ascites
def: "An abdominal symptom consisting of an abnormal accumulation of serous fluid in the spaces between tissues and organs in the cavity of the abdomen." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=ascites]
synonym: "hydroperitoneum" EXACT []
xref: ICD9CM_2005:789.5
xref: UMLS_CUI:C0003962
xref: UMLS_ICD9CM_2005_AUI:A0026882
is_a: SYMP:0000461 ! abdominal symptom

[Term]
id: SYMP:0000527
name: undiagnosed cardiac murmur
xref: ICD9CM_2005:785.2
xref: UMLS_CUI:C0375546
xref: UMLS_ICD9CM_2005_AUI:A0813487
is_a: SYMP:0000528 ! cardiovascular system symptom

[Term]
id: SYMP:0000528
name: cardiovascular system symptom
xref: ICD9CM_2005:785
xref: UMLS_CUI:C0159049
xref: UMLS_ICD9CM_2005_AUI:A0284192
is_a: SYMP:0000462 ! symptom

[Term]
id: SYMP:0000529
name: tachycardia
def: "Tachycardia is a cardiovascular system symptom consisting of a relatively rapid heart action whether physiological (as after exercise) or pathological." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=tachycardia]
xref: ICD9CM_2005:785.0
xref: UMLS_CUI:C0039231
xref: UMLS_ICD9CM_2005_AUI:A0804597
is_a: SYMP:0000287 ! arrhythmia

[Term]
id: SYMP:0000530
name: palpitation
def: "Palpitation is a cardiovascykar system symptom characterized by an abnormal awareness of the beating of the heart,whether it is too slow, too fast, irregular, or at its normal frequency when excited by violent exertion, strong emotion, or disease." [url:http\://en.wikipedia.org/wiki/Palpitation, url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=palpitation]
synonym: "abnormal heart beats" EXACT []
xref: ICD9CM_2005:785.1
xref: UMLS_CUI:C0030252
xref: UMLS_ICD9CM_2005_AUI:A0004066
is_a: SYMP:0000528 ! cardiovascular system symptom

[Term]
id: SYMP:0000531
name: splenomegaly
synonym: "esplenomegaly" EXACT []
xref: ICD9CM_2005:789.2
xref: UMLS_CUI:C0038002
xref: UMLS_ICD9CM_2005_AUI:A0118748
is_a: SYMP:0000158 ! spleen symptom

[Term]
id: SYMP:0000532
name: urge incontinence
def: "A urinary incontinence that is characterized by an involuntary leakage of urine from the bladder when a sudden strong need to urinate is felt, even when the bladder isn't full." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=urge%20incontinence, url:https\://www.health.harvard.edu/bladder-and-bowel/types-of-urinary-incontinence]
xref: ICD9CM_2005:788.31
xref: UMLS_CUI:C0150045
xref: UMLS_ICD9CM_2005_AUI:A0469078
is_a: SYMP:0000492 ! urinary incontinence

[Term]
id: SYMP:0000533
name: post-void dribbling
def: "A urinary incontinence that is characterized by urine remaining in the urethra after voiding the bladder that slowly leaks out after urination." [url:https\://en.wikipedia.org/wiki/Post-void_dribbling]
xref: ICD9CM_2005:788.35
xref: UMLS_CUI:C0375552
xref: UMLS_ICD9CM_2005_AUI:A0775329
is_a: SYMP:0000492 ! urinary incontinence

[Term]
id: SYMP:0000534
name: spontaneous ecchymoses
def: "A skin and integumentary tissue symptom that is characterized by the spontaneous escape of blood into the tissues from ruptured blood vessels marked by a livid black-and-blue or purple spot or area." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=ecchymoses]
xref: ICD9CM_2005:782.7
xref: UMLS_CUI:C0159039
xref: UMLS_ICD9CM_2005_AUI:A0284153
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000535
name: change in skin texture
xref: ICD9CM_2005:782.8
xref: UMLS_CUI:C0159040
xref: UMLS_ICD9CM_2005_AUI:A0284158
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000536
name: disturbance of skin sensation
xref: ICD9CM_2005:782.0
xref: UMLS_CUI:C0012766
xref: UMLS_ICD9CM_2005_AUI:A0243776
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000537
name: cyanosis
def: "A skin and integumentary tissue symptom that is characterized by a bluish or purplish discoloration (as of skin) due to deficient oxygenation of the blood." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=cyanosis]
xref: ICD9CM_2005:782.5
xref: UMLS_CUI:C0010520
xref: UMLS_ICD9CM_2005_AUI:A0044296
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000538
name: edema
def: "A skin and integumentary tissue symptom that is characterized by an abnormal excess accumulation of serous fluid in connective tissue or in a serous cavity." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=edema]
synonym: "dropsy" EXACT []
xref: ICD9CM_2005:782.3
xref: UMLS_CUI:C0013604
xref: UMLS_ICD9CM_2005_AUI:A0052720
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000539
name: jaundice
def: "A skin and integumentary tissue symptom that is characterized by a yellowish pigmentation of the skin, tissues, and certain body fluids is caused by the deposition of bile pigments that follows interference with normal production and discharge of bile (as in certain liver diseases) or excessive breakdown of red blood cells (as after internal hemorrhage or in various hemolytic states)." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=jaundice]
synonym: "icteric" EXACT []
synonym: "icterus" EXACT []
xref: ICD9CM_2005:782.4
xref: UMLS_CUI:C0476232
xref: UMLS_ICD9CM_2005_AUI:A0243785
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000540
name: painful respiration
def: "A respiratory system and chest symptom that is characterized by a feeling of discomfort when breathing in or out.  The pain may be the result of infection, musculoskeletal injury, and heart problems." [url:https\://www.healthline.com/health/painful-respiration#causes, url:https\://www.medicalnewstoday.com/articles/324718]
xref: ICD9CM_2005:786.52
xref: UMLS_CUI:C0423729
xref: UMLS_ICD9CM_2005_AUI:A0243833
is_a: SYMP:0000514 ! respiratory system and chest symptom

[Term]
id: SYMP:0000541
name: periumbilic abdominal swelling
xref: ICD9CM_2005:789.35
xref: UMLS_CUI:C0375561
xref: UMLS_ICD9CM_2005_AUI:A0637126
is_a: SYMP:0000478 ! abdominal swelling

[Term]
id: SYMP:0000542
name: epigastric abdominal pain
def: "An abdominal pain that is characterized by occurring in the epigastrium, i.e. the upper part of the abdomen below the rib cage." [url:https\://info.isabelhealthcare.com/blog/why-does-my-stomach-hurt-epigastric-pain-symptoms-and-causes, url:https\://www.healthline.com/health/epigastric-pain]
xref: ICD9CM_2005:789.06
xref: UMLS_CUI:C0232493
xref: UMLS_ICD9CM_2005_AUI:A0637130
is_a: SYMP:0000457 ! abdominal pain

[Term]
id: SYMP:0000543
name: memory loss
def: "A neurological and physiological symptom that is characterized by an unusual forgetfulness. One may not be able to remember new events, recall one or more memories of the past, or both.  Memory loss may be for a short time and then resolve (transient), or it may not go away and get worse over time." [url:https\://medlineplus.gov/ency/article/003257.htm, url:https\://www.merckmanuals.com/professional/neurologic-disorders/symptoms-of-neurologic-disorders/memory-loss]
xref: ICD9CM_2005:780.93
xref: UMLS_CUI:C0751295
xref: UMLS_ICD9CM_2005_AUI:A2797424
is_a: SYMP:0000410 ! neurological and physiological symptom

[Term]
id: SYMP:0000544
name: transient paralysis of limb
def: "A paralysis that is characterized by a loss of some, or all, muscle control in a limb, and which lasts for only a short time (i.e. is temporary)." [url:https\://dictionary.cambridge.org/us/dictionary/english/transient, url:https\://www.spinalcord.com/blog/what-causes-temporary-paralysis]
xref: ICD9CM_2005:781.4
xref: UMLS_CUI:C0159034
xref: UMLS_ICD9CM_2005_AUI:A0284133
is_a: SYMP:0000030 ! paralysis

[Term]
id: SYMP:0000545
name: multiple sites abdominal swelling
xref: ICD9CM_2005:789.39
xref: UMLS_CUI:C0375564
xref: UMLS_ICD9CM_2005_AUI:A0637125
is_a: SYMP:0000478 ! abdominal swelling

[Term]
id: SYMP:0000546
name: right lower quadrant abdominal pain
xref: ICD9CM_2005:789.03
xref: UMLS_CUI:C0740603
is_a: SYMP:0000457 ! abdominal pain

[Term]
id: SYMP:0000547
name: right upper quadrant abdominal pain
xref: ICD9CM_2005:789.01
xref: UMLS_CUI:C0235299
is_a: SYMP:0000457 ! abdominal pain

[Term]
id: SYMP:0000548
name: right lower quadrant abdominal swelling
xref: ICD9CM_2005:789.33
xref: UMLS_CUI:C0375559
is_a: SYMP:0000478 ! abdominal swelling

[Term]
id: SYMP:0000549
name: generalized abdominal swelling
xref: ICD9CM_2005:789.37
xref: UMLS_CUI:C0375563
xref: UMLS_ICD9CM_2005_AUI:A0637122
is_a: SYMP:0000478 ! abdominal swelling

[Term]
id: SYMP:0000550
name: clubbing of fingers
xref: ICD9CM_2005:781.5
xref: UMLS_CUI:C0009080
xref: UMLS_ICD9CM_2005_AUI:A0284139
is_a: SYMP:0000891 ! musculoskeletal system symptom

[Term]
id: SYMP:0000551
name: disturbances of sensation of smell and taste
synonym: "taste alteration" EXACT []
xref: ICD9CM_2005:781.1
xref: UMLS_CUI:C0495689
xref: UMLS_ICD9CM_2005_AUI:A0243765
is_a: SYMP:0000480 ! nervous system symptom

[Term]
id: SYMP:0000552
name: meningismus
def: "A nervous system symptom that is characterized by a state of meningeal irritation with symptoms suggesting meningitis that often occurs at the onset of acute febrile diseases especially in children." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=meningismus]
xref: ICD9CM_2005:781.6
xref: UMLS_CUI:C0025287
xref: UMLS_ICD9CM_2005_AUI:A0434815
is_a: SYMP:0000480 ! nervous system symptom

[Term]
id: SYMP:0000553
name: neurologic neglect syndrome
xref: ICD9CM_2005:781.8
xref: UMLS_CUI:C0840927
xref: UMLS_ICD9CM_2005_AUI:A0752424
is_a: SYMP:0000480 ! nervous system symptom

[Term]
id: SYMP:0000554
name: left lower quadrant abdominal rigidity
xref: ICD9CM_2005:789.44
xref: UMLS_CUI:C0375568
xref: UMLS_ICD9CM_2005_AUI:A0637143
is_a: SYMP:0000454 ! abdominal rigidity

[Term]
id: SYMP:0000555
name: left upper quadrant abdominal swelling
xref: ICD9CM_2005:789.32
xref: UMLS_CUI:C0375558
xref: UMLS_ICD9CM_2005_AUI:A0637124
is_a: SYMP:0000478 ! abdominal swelling

[Term]
id: SYMP:0000556
name: localized superficial lump
xref: ICD9CM_2005:782.2
xref: UMLS_CUI:C0476228
xref: UMLS_ICD9CM_2005_AUI:A0243783
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000557
name: urinary retention
def: "A urinary system symptom that is characterized by an inability to empty the bladder completely during the process of voiding (urination)." [url:https\://en.wikipedia.org/wiki/Urinary_retention]
synonym: "inability to urinate" EXACT []
synonym: "ischuria" EXACT []
synonym: "retention of urine" EXACT []
xref: ICD9CM_2005:788.2
xref: ICD9CM_2005:788.20
xref: UMLS_CUI:C0080274
xref: UMLS_ICD9CM_2005_AUI:A0284250
xref: UMLS_ICD9CM_2005_AUI:A0784422
is_a: SYMP:0000486 ! urinary system symptom

[Term]
id: SYMP:0000558
name: incomplete bladder emptying
def: "A urinary system symptom that is characterized by a bladder that is not empty." []
xref: ICD9CM_2005:788.21
xref: UMLS_CUI:C0344365
xref: UMLS_ICD9CM_2005_AUI:A0722424
is_a: SYMP:0000486 ! urinary system symptom

[Term]
id: SYMP:0000559
name: voice disturbance
xref: ICD9CM_2005:784.4
xref: ICD9CM_2005:784.40
xref: UMLS_CUI:C0042940
xref: UMLS_ICD9CM_2005_AUI:A0284182
xref: UMLS_ICD9CM_2005_AUI:A0818015
is_a: SYMP:0000386 ! mouth symptom

[Term]
id: SYMP:0000560
name: polydipsia
def: "A nutrition, metabolism, and development symptom that is characterized by an excessive or abnormal thirst." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=polydipsia]
xref: ICD9CM_2005:783.5
xref: UMLS_CUI:C0085602
xref: UMLS_ICD9CM_2005_AUI:A0003974
is_a: SYMP:0000473 ! nutrition, metabolism, and development symptom

[Term]
id: SYMP:0000561
name: multiple sites abdominal pain
xref: ICD9CM_2005:789.09
xref: UMLS_CUI:C0375555
xref: UMLS_ICD9CM_2005_AUI:A0637134
is_a: SYMP:0000457 ! abdominal pain

[Term]
id: SYMP:0000562
name: right upper quadrant abdominal swelling
xref: ICD9CM_2005:789.31
xref: UMLS_CUI:C0375557
is_a: SYMP:0000478 ! abdominal swelling

[Term]
id: SYMP:0000563
name: urinary frequency
def: "A urinary system symptom that is characterized by the need to urinate many times during the day, at night, or both but in normal or less-than-normal volumes.  Frequency may be accompanied by a sensation of an urgent need to void (urgency of urination)." [url:https\://www.merckmanuals.com/professional/genitourinary-disorders/symptoms-of-genitourinary-disorders/urinary-frequency]
synonym: "frequent urination" EXACT []
synonym: "nocturia" RELATED []
xref: ICD9CM_2005:788.41
xref: UMLS_CUI:C0042023
xref: UMLS_ICD9CM_2005_AUI:A0004030
is_a: SYMP:0000486 ! urinary system symptom

[Term]
id: SYMP:0000564
name: nocturia
def: "A urinary system symptom that is characterized by urination at night especially when excessive." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=nocturia]
synonym: "nycturia" EXACT []
xref: ICD9CM_2005:788.43
xref: UMLS_CUI:C0028734
xref: UMLS_ICD9CM_2005_AUI:A0011475
is_a: SYMP:0000486 ! urinary system symptom

[Term]
id: SYMP:0000565
name: polyuria
def: "A urinary system symptom that is characterized by the excessive secretion of urine." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=polyuria]
synonym: "excessive secretion of urine" EXACT []
xref: ICD9CM_2005:788.42
xref: UMLS_CUI:C0032617
xref: UMLS_ICD9CM_2005_AUI:A0103470
is_a: SYMP:0000486 ! urinary system symptom

[Term]
id: SYMP:0000566
name: sleep disturbance
xref: ICD9CM_2005:780.5
xref: UMLS_CUI:C0037317
xref: UMLS_ICD9CM_2005_AUI:A0246756
is_a: SYMP:0000567 ! general symptom

[Term]
id: SYMP:0000567
name: general symptom
xref: ICD9CM_2005:780
xref: UMLS_CUI:C0159028
xref: UMLS_ICD9CM_2005_AUI:A0284119
is_a: SYMP:0000462 ! symptom

[Term]
id: SYMP:0000568
name: short stature
def: "A lack of expected normal physiological development in childhood that is characterized by an individual's height being in the 3rd percentile for the mean height of a given age, sex, and population group." [url:https\://www.ncbi.nlm.nih.gov/books/NBK556031/]
xref: ICD9CM_2005:783.43
xref: UMLS_CUI:C0349588
is_a: SYMP:0000464 ! lack of expected normal physiological development in childhood

[Term]
id: SYMP:0000569
name: oliguria
def: "A urinary system symptom that is characterized by the reduced excretion of urine." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=oliguria]
xref: ICD9CM_2005:788.5
xref: UMLS_CUI:C0028962
xref: UMLS_ICD9CM_2005_AUI:A0243854
is_a: SYMP:0000486 ! urinary system symptom

[Term]
id: SYMP:0000570
name: diarrhea
def: "Diarrhea is a feces and droppng symptom involving the abnormally frequent intestinal evacuations with more or less fluid stools." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=diarrhea]
comment: doid/symp duplicate - reviewed 10/2022, both DO & SYMP
synonym: "bacterial gastroenteritis" EXACT []
synonym: "diarrhoea" EXACT []
synonym: "fecal incontinence" EXACT []
synonym: "incontinence of feces" EXACT []
synonym: "loose bowel" EXACT []
synonym: "loose bowels" EXACT []
synonym: "the runs" EXACT []
xref: ICD9CM_2005:787.91
xref: UMLS_CUI:C0011991
xref: UMLS_ICD9CM_2005_AUI:A0048148
is_a: SYMP:0000146 ! feces and droppings symptom

[Term]
id: SYMP:0000571
name: insomnia
def: "Insomnia is a sleep disturbance characterized by prolonged and usually abnormal inability to obtain adequate sleep." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=insomnia]
synonym: "agrypnia" EXACT []
xref: ICD9CM_2005:780.52
xref: UMLS_CUI:C0029645
xref: UMLS_ICD9CM_2005_AUI:A0243733
is_a: SYMP:0000566 ! sleep disturbance

[Term]
id: SYMP:0000572
name: splitting of urinary stream
def: "A urinary stream symptom that is characterized by a split in the urine flow resulting in it streaming in two directions." [url:https\://ugatl.com/services/prostatitis/splitting-urine-stream/]
xref: ICD9CM_2005:788.61
xref: UMLS_CUI:C0232855
xref: UMLS_ICD9CM_2005_AUI:A0460440
is_a: SYMP:0000573 ! urinary stream symptom

[Term]
id: SYMP:0000573
name: urinary stream symptom
xref: ICD9CM_2005:788.6
xref: ICD9CM_2005:788.69
xref: UMLS_CUI:C0159063
xref: UMLS_ICD9CM_2005_AUI:A0284254
xref: UMLS_ICD9CM_2005_AUI:A0284255
is_a: SYMP:0000486 ! urinary system symptom

[Term]
id: SYMP:0000574
name: aphonia
xref: ICD9CM_2005:784.41
xref: UMLS_CUI:C0003564
xref: UMLS_ICD9CM_2005_AUI:A0025595
is_a: SYMP:0000559 ! voice disturbance

[Term]
id: SYMP:0000575
name: precordial pain
xref: ICD9CM_2005:786.51
xref: UMLS_CUI:C0232286
xref: UMLS_ICD9CM_2005_AUI:A0284212
is_a: SYMP:0000576 ! chest pain

[Term]
id: SYMP:0000576
name: chest pain
xref: ICD9CM_2005:786.5
xref: ICD9CM_2005:786.50
xref: UMLS_CUI:C0008031
xref: UMLS_ICD9CM_2005_AUI:A0243830
xref: UMLS_ICD9CM_2005_AUI:A0400627
is_a: SYMP:0000099 ! pain

[Term]
id: SYMP:0000577
name: fussy infant
xref: ICD9CM_2005:780.91
xref: UMLS_CUI:C1135254
xref: UMLS_ICD9CM_2005_AUI:A2358677
is_a: SYMP:0000411 ! infant symptom

[Term]
id: SYMP:0000578
name: incontinence without sensory awareness
xref: ICD9CM_2005:788.34
xref: UMLS_CUI:C0375551
xref: UMLS_ICD9CM_2005_AUI:A0722462
is_a: SYMP:0000492 ! urinary incontinence

[Term]
id: SYMP:0000579
name: insomnia with sleep apnea
xref: ICD9CM_2005:780.51
xref: UMLS_CUI:C0159030
xref: UMLS_ICD9CM_2005_AUI:A0284123
is_a: SYMP:0000571 ! insomnia

[Term]
id: SYMP:0000580
name: dysfunctions associated with sleep stages
xref: ICD9CM_2005:780.56
xref: UMLS_CUI:C0013373
xref: UMLS_ICD9CM_2005_AUI:A0243741
is_a: SYMP:0000566 ! sleep disturbance

[Term]
id: SYMP:0000581
name: sleep apnea
def: "An apnea that is characterized by brief periods of recurrent cessation of breathing during sleep that is caused especially by obstruction of the airway or a disturbance in the brain's respiratory center and is associated especially with excessive daytime sleepiness." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=sleep%20apnea]
comment: doid/symp duplicate
xref: ICD9CM_2005:780.57
xref: UMLS_CUI:C0375544
xref: UMLS_ICD9CM_2005_AUI:A0760143
is_a: SYMP:0000600 ! apnea

[Term]
id: SYMP:0000582
name: hypersomnia
def: "Hypersomnia is a sleep disturbance characterized by sleeping for excessive periods at intervals with intervening periods of normal duration of sleeping and waking." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=hypersomnia]
xref: ICD9CM_2005:780.54
xref: UMLS_CUI:C0029637
xref: UMLS_ICD9CM_2005_AUI:A0243739
is_a: SYMP:0000566 ! sleep disturbance

[Term]
id: SYMP:0000583
name: hypersomnia with sleep apnea
xref: ICD9CM_2005:780.53
xref: UMLS_CUI:C0020530
xref: UMLS_ICD9CM_2005_AUI:A0243735
is_a: SYMP:0000582 ! hypersomnia

[Term]
id: SYMP:0000584
name: disruptions of 24-hour sleep-wake cycle
xref: ICD9CM_2005:780.55
xref: UMLS_CUI:C0159031
xref: UMLS_ICD9CM_2005_AUI:A0284127
is_a: SYMP:0000566 ! sleep disturbance

[Term]
id: SYMP:0000585
name: sleep related movement disorder
xref: ICD9CM_2005:780.58
xref: UMLS_CUI:C1455873
xref: UMLS_ICD9CM_2005_AUI:A6995224
is_a: SYMP:0000566 ! sleep disturbance

[Term]
id: SYMP:0000586
name: overflow incontinence
def: "A urinary incontinence that is characterized by a bladder that does not empty completely, resulting in a bladder that is too full, which leads to overflow and unexpected leaking." [url:https\://www.health.harvard.edu/bladder-and-bowel/types-of-urinary-incontinence, url:https\://www.healthline.com/health/overactive-bladder/overflow-incontinence, url:https\://www.webmd.com/urinary-incontinence-oab/overflow-incontinence]
xref: ICD9CM_2005:788.38
xref: UMLS_CUI:C0312413
xref: UMLS_ICD9CM_2005_AUI:A6994689
is_a: SYMP:0000492 ! urinary incontinence

[Term]
id: SYMP:0000587
name: abnormal chest sound
def: "A respiratory system and chest symptom that is characterized by a sound of breathing that is not similar to that of the sound of moving air and may include: rhonchi (a low-pitched breath sound), crackles (a high-pitched breath sound), wheezing (a high-pitched whistling sound caused by narrowing of the bronchial tubes), and stridor (a harsh, vibratory sound caused by narrowing of the upper airway)." [url:https\://www.healthline.com/health/breath-sounds#types]
xref: ICD9CM_2005:786.7
xref: UMLS_CUI:C0159056
xref: UMLS_ICD9CM_2005_AUI:A0284219
is_a: SYMP:0000514 ! respiratory system and chest symptom

[Term]
id: SYMP:0000588
name: extravasation of urine
def: "A urinary system symptom that is characterized by an injury of the urethra in its bulbous or membranous portion, which leads to a collection of urine in other cavities, such as the perineal space, the scrotum, the penis and the connective tissue of the anterior abdominal wall." [url:https\://en.wikipedia.org/wiki/Extravasation_of_urine, url:https\://jamanetwork.com/journals/jama/article-abstract/466994]
xref: ICD9CM_2005:788.8
xref: UMLS_CUI:C0152245
xref: UMLS_ICD9CM_2005_AUI:A0284259
is_a: SYMP:0000486 ! urinary system symptom

[Term]
id: SYMP:0000589
name: slowing of urinary stream
def: "A urinary stream symptom that is characterized by a slow or weak stream of urine." [url:https\://www.besturologistnyc.com/what-is-slow-urine-flow]
xref: ICD9CM_2005:788.62
xref: UMLS_CUI:C0232854
xref: UMLS_ICD9CM_2005_AUI:A0459374
is_a: SYMP:0000573 ! urinary stream symptom

[Term]
id: SYMP:0000590
name: urinary urgency
def: "A urinary system symptom that is characterized by a strong and immediate need to urinate due to an increase in pressure in the bladder, resulting in difficulty to hold in the urine. This can occur regardless of whether the bladder is full." [url:https\://www.medicalnewstoday.com/articles/325336#symptoms]
synonym: "urgency of urination" EXACT []
xref: ICD9CM_2005:788.63
xref: UMLS_CUI:C0085606
xref: UMLS_ICD9CM_2005_AUI:A2797703
is_a: SYMP:0000486 ! urinary system symptom

[Term]
id: SYMP:0000591
name: left upper quadrant abdominal tenderness
xref: ICD9CM_2005:789.62
xref: UMLS_CUI:C0238566
xref: UMLS_ICD9CM_2005_AUI:A0637156
is_a: SYMP:0000484 ! abdominal tenderness

[Term]
id: SYMP:0000592
name: excessive crying of infant
xref: ICD9CM_2005:780.92
xref: UMLS_CUI:C0497134
xref: UMLS_ICD9CM_2005_AUI:A2358671
is_a: SYMP:0000411 ! infant symptom

[Term]
id: SYMP:0000593
name: gangrene
xref: ICD9CM_2005:785.4
xref: UMLS_CUI:C0017086
xref: UMLS_ICD9CM_2005_AUI:A0061978
is_a: SYMP:0000528 ! cardiovascular system symptom

[Term]
id: SYMP:0000594
name: abnormal involuntary movement
def: "A nervous system symptom that is characterized by an inability to control bodily movement and may be a symptom of cerebrovascular diseases, dyskinesia, tremor, chorea, dystonia and myoclonus." [url:https\://patient.info/doctor/abnormal-involuntary-movements, url:https\://stanfordmedicine25.stanford.edu/the25/involuntary-movements-and-tremors.html]
xref: ICD9CM_2005:781.0
xref: UMLS_CUI:C0392702
xref: UMLS_ICD9CM_2005_AUI:A0243762
is_a: SYMP:0000480 ! nervous system symptom

[Term]
id: SYMP:0000595
name: febrile convulsion
def: "A convulsion that is characterized by occurring in young children between six months and five years of age and which is triggered by fever." [url:https\://www.ninds.nih.gov/febrile-seizures-fact-sheet, url:https\://www.webmd.com/a-to-z-guides/swollen-glands]
synonym: "febrile seizure" EXACT []
xref: ICD9CM_2005:780.31
xref: UMLS_CUI:C0009952
xref: UMLS_ICD9CM_2005_AUI:A0701466
is_a: SYMP:0000596 ! convulsion

[Term]
id: SYMP:0000596
name: convulsion
def: "A nervous system symptom that is characterized by an abnormal violent and involuntary contraction or series of contractions of the muscles." [url:https\://www.merriam-webster.com/dictionary/convulsion]
xref: ICD9CM_2005:780.3
xref: UMLS_CUI:C0009951
xref: UMLS_ICD9CM_2005_AUI:A0042665
is_a: SYMP:0000480 ! nervous system symptom

[Term]
id: SYMP:0000597
name: head and neck symptom
xref: ICD9CM_2005:784
xref: UMLS_CUI:C0476247
xref: UMLS_ICD9CM_2005_AUI:A0284173
is_a: SYMP:0000462 ! symptom

[Term]
id: SYMP:0000598
name: respiratory abnormality
def: "A respiratory system and chest symptom that is characterized by a respiration that is not normal and may include, but is not limited to: apnea, eupnea, orthopnea, dyspnea hyperpnea, hyperventilation, hypoventilation, tachypnea, Kussmaul respiration, Cheyne-Stokes respiration, sighing respiration, Biot respiration, apneustic breathing, central neurogenic hyperventilation, and central neurogenic hypoventilation." [url:https\://www.ncbi.nlm.nih.gov/books/NBK470309/]
xref: ICD9CM_2005:786.0
xref: UMLS_CUI:C0159053
xref: UMLS_ICD9CM_2005_AUI:A0284202
is_a: SYMP:0000514 ! respiratory system and chest symptom

[Term]
id: SYMP:0000599
name: cheyne-stokes respiration
def: "A respiratory abnormality that is characterized by a specific form of periodic breathing (waxing and waning amplitude of flow or tidal volume) characterized by a crescendo-decrescendo pattern of respiration between central apneas or central hypopneas." [url:https\://www.ncbi.nlm.nih.gov/books/NBK448165/]
xref: ICD9CM_2005:786.04
xref: UMLS_CUI:C0008039
xref: UMLS_ICD9CM_2005_AUI:A0400651
is_a: SYMP:0000598 ! respiratory abnormality

[Term]
id: SYMP:0000600
name: apnea
def: "A respiratory abnormality that is characterized by transient cessation of respiration whether normal (as in hibernating animals) or abnormal (as that caused by certain drugs)." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=apnea]
xref: ICD9CM_2005:786.03
xref: UMLS_CUI:C0003578
xref: UMLS_ICD9CM_2005_AUI:A0025648
is_a: SYMP:0000598 ! respiratory abnormality

[Term]
id: SYMP:0000601
name: hyperventilation
def: "A respiratory abnormality that is characterized by excessive ventilation characterized by excessive rate and depth of respiration leading to abnormal loss of carbon dioxide from the blood." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=hyperventilation]
xref: ICD9CM_2005:786.01
xref: UMLS_CUI:C0020578
xref: UMLS_ICD9CM_2005_AUI:A0071094
is_a: SYMP:0000598 ! respiratory abnormality

[Term]
id: SYMP:0000602
name: orthopnea
def: "A respiratory abnormality that is characterized by a difficulty in breathing that occurs when lying down and is relieved upon changing to an upright position (as in congestive heart failure)." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=orthopnea]
xref: ICD9CM_2005:786.02
xref: UMLS_CUI:C0085619
xref: UMLS_ICD9CM_2005_AUI:A0004140
is_a: SYMP:0000598 ! respiratory abnormality

[Term]
id: SYMP:0000603
name: tachypnea
alt_id: SYMP:0000683
def: "A respiratory abnormality that is characterized by an increased rate of respiration and shallow breathing." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=tachypnea, url:https\://www.healthline.com/health/rapid-shallow-breathing]
synonym: "rapid breathing" EXACT []
xref: ICD9CM_2005:786.06
xref: UMLS_CUI:C0231835
xref: UMLS_ICD9CM_2005_AUI:A0465027
is_a: SYMP:0000598 ! respiratory abnormality

[Term]
id: SYMP:0000604
name: wheezing
def: "An abnormal chest sound that is characterized by breathing with difficulty usually with a whistling sound." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=wheezing]
xref: ICD9CM_2005:786.07
xref: UMLS_CUI:C0043144
xref: UMLS_ICD9CM_2005_AUI:A0133941
is_a: SYMP:0000587 ! abnormal chest sound

[Term]
id: SYMP:0000605
name: coma
def: "An alteration of consciousness that is characterized by a deep state of prolonged unconsciousness in which a person cannot be awakened, fails to respond normally to painful stimuli, light, or sound, lacks a normal wake-sleep cycle and does not initiate voluntary actions." [url:https\://en.wikipedia.org/wiki/Coma]
xref: ICD9CM_2005:780.01
xref: UMLS_CUI:C0009421
xref: UMLS_ICD9CM_2005_AUI:A0041160
is_a: SYMP:0000482 ! alteration of consciousness

[Term]
id: SYMP:0000606
name: nocturnal enuresis
def: "A urinary incontinence that is characterized by involuntary urination at night in children five years of age or older." [url:https\://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348193/]
synonym: "bed wetting" EXACT []
synonym: "nighttime incontinence" EXACT []
xref: ICD9CM_2005:788.36
xref: UMLS_CUI:C0270327
xref: UMLS_ICD9CM_2005_AUI:A0753297
is_a: SYMP:0000492 ! urinary incontinence

[Term]
id: SYMP:0000607
name: hallucination
def: "Hallucination is a general symptom where there is a perception of something (as a visual image or a sound) with no external cause usually arising from a disorder of the nervous system (as in delirium tremens or in functional psychosis without known neurological disease) or in response to drugs (as LSD)." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=hallucinations]
xref: ICD9CM_2005:780.1
xref: UMLS_CUI:C0018524
xref: UMLS_ICD9CM_2005_AUI:A0065642
is_a: SYMP:0000567 ! general symptom

[Term]
id: SYMP:0000608
name: syncope and collapse
def: "An alteration of consciousness that is characterized by a loss of consciousness resulting from insufficient blood flow to the brain and limb weakness progressing to collapse." [url:https\://en.wikipedia.org/wiki/Syncope_(medicine)]
xref: ICD9CM_2005:780.2
xref: UMLS_CUI:C0039070
xref: UMLS_ICD9CM_2005_AUI:A0243721
is_a: SYMP:0000482 ! alteration of consciousness

[Term]
id: SYMP:0000609
name: generalized hyperhidrosis
def: "A neurological and physiological symptom that is characterized by excessive sweating, i.e. the production of more sweat than is required to regulate body temperature.  Generalized hyperhidrosis is caused by non-thermoregulatory stimuli and affects the entire body." [url:https\://sydneynorthneurology.com.au/generalised-hyperhidrosis/]
synonym: "secondary hyperhidrosis" EXACT []
xref: ICD9CM_2005:780.8
xref: UMLS_CUI:C0476476
xref: UMLS_ICD9CM_2005_AUI:A6994739
is_a: SYMP:0000410 ! neurological and physiological symptom

[Term]
id: SYMP:0000610
name: dizziness
def: "A  balance symptom that is characterized by a sensation of unsteadiness accompanied by a feeling of movement within the head." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=dizziness]
synonym: "dizzy" EXACT []
xref: ICD9CM_2005:780.4
xref: UMLS_CUI:C0476206
xref: UMLS_ICD9CM_2005_AUI:A0243727
is_a: SYMP:0020045 ! balance symptom

[Term]
id: SYMP:0000611
name: periumbilic abdominal pain
xref: ICD9CM_2005:789.05
xref: UMLS_CUI:C0740594
xref: UMLS_ICD9CM_2005_AUI:A0637135
is_a: SYMP:0000457 ! abdominal pain

[Term]
id: SYMP:0000612
name: periumbilic abdominal rigidity
xref: ICD9CM_2005:789.45
xref: UMLS_CUI:C0375569
xref: UMLS_ICD9CM_2005_AUI:A0637146
is_a: SYMP:0000454 ! abdominal rigidity

[Term]
id: SYMP:0000613
name: fever
def: "A neurological and physiological symptom that is characterized by a rise of body temperature above the normal, whether as a natural response (as to infection) or artificially induced for therapeutic reasons." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=fever]
synonym: "pyrexia" EXACT []
xref: ICD9CM_2005:780.6
xref: UMLS_CUI:C0015967
xref: UMLS_ICD9CM_2005_AUI:A0058972
is_a: SYMP:0000410 ! neurological and physiological symptom

[Term]
id: SYMP:0000614
name: cough
def: "A respiratory system and chest symptom that is characterized by an explosive expulsion of air from the lungs acting as a protective mechanism to clear the air passages or as a symptom of pulmonary disturbance." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=cough]
xref: ICD9CM_2005:786.2
xref: UMLS_CUI:C0010200
xref: UMLS_ICD9CM_2005_AUI:A0043303
is_a: SYMP:0000514 ! respiratory system and chest symptom

[Term]
id: SYMP:0000615
name: obsolete lack of coordination
xref: ICD9CM_2005:781.3
xref: UMLS_CUI:C0520966
xref: UMLS_ICD9CM_2005_AUI:A0243769
is_obsolete: true
replaced_by: SYMP:0000164

[Term]
id: SYMP:0000616
name: loss of height
xref: ICD9CM_2005:781.91
xref: UMLS_CUI:C0424641
xref: UMLS_ICD9CM_2005_AUI:A1892812
is_a: SYMP:0000891 ! musculoskeletal system symptom

[Term]
id: SYMP:0000617
name: torticollis
synonym: "twisted neck" EXACT []
synonym: "wry neck" EXACT []
xref: ICD9CM_2005:781.93
xref: UMLS_CUI:C0028856
xref: UMLS_ICD9CM_2005_AUI:A2358774
is_a: SYMP:0000891 ! musculoskeletal system symptom

[Term]
id: SYMP:0000618
name: abnormal posture
xref: ICD9CM_2005:781.92
xref: UMLS_CUI:C0231471
xref: UMLS_ICD9CM_2005_AUI:A0387502
is_a: SYMP:0000891 ! musculoskeletal system symptom

[Term]
id: SYMP:0000619
name: tetany
xref: ICD9CM_2005:781.7
xref: UMLS_CUI:C0039621
xref: UMLS_ICD9CM_2005_AUI:A0124526
is_a: SYMP:0000891 ! musculoskeletal system symptom

[Term]
id: SYMP:0000620
name: left lower quadrant abdominal pain
def: "An abdominal pain that is characterized by occurring in the left lower quadrant of the abdomen that is often related to the digestive tract, but can also be related to conditions of the body wall, skin, blood vessels, urinary tract, or reproductive organs." [url:https\://www.healthgrades.com/right-care/symptoms-and-conditions/left-lower-quadrant-pain]
xref: ICD9CM_2005:789.04
xref: UMLS_CUI:C0238551
xref: UMLS_ICD9CM_2005_AUI:A0637132
is_a: SYMP:0000457 ! abdominal pain

[Term]
id: SYMP:0000621
name: alexia
def: "An aphasia that is characterized by a loss of ability to read." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=alexia]
comment: doid/symp duplicate
xref: ICD9CM_2005:784.6
xref: ICD9CM_2005:784.69
xref: UMLS_CUI:C0478145
xref: UMLS_ICD9CM_2005_AUI:A0243803
xref: UMLS_ICD9CM_2005_AUI:A0243804
is_a: SYMP:0000508 ! aphasia

[Term]
id: SYMP:0000622
name: acute mesenteric lymphadenitis
is_a: SYMP:0019155 ! lymphadenitis

[Term]
id: SYMP:0000623
name: acute renal failure
def: "A renal failure that is characterized by a severe and sudden onset of renal failure." []
is_a: SYMP:0000731 ! renal failure

[Term]
id: SYMP:0000624
name: obsolete appendicitis
is_obsolete: true

[Term]
id: SYMP:0000625
name: conscious disturbance
def: "An alteration of consciousness that is characterized by a disturbance in sentience (the ability to experience feelings and sensations) or awareness of one's internal and external existence, i.e. inhibited or absent self-awareness." [url:https\://en.wikipedia.org/wiki/Consciousness, url:https\://en.wikipedia.org/wiki/Disorders_of_consciousness]
is_a: SYMP:0000482 ! alteration of consciousness

[Term]
id: SYMP:0000626
name: obsolete myalgia
is_obsolete: true
replaced_by: SYMP:0019161

[Term]
id: SYMP:0000627
name: disturbed vision
synonym: "disturbance of vision" EXACT []
is_a: SYMP:0000628 ! vision distortion

[Term]
id: SYMP:0000628
name: vision distortion
is_a: SYMP:0000320 ! vision symptom

[Term]
id: SYMP:0000629
name: exanthema
def: "A rash characterized by a widespread skin eruption usually occurring in children that is a symptom of a more general disease." [url:http\://en.wikipedia.org/wiki/Exanthema]
is_a: SYMP:0000487 ! rash

[Term]
id: SYMP:0000630
name: frontal headache
is_a: SYMP:0000504 ! headache

[Term]
id: SYMP:0000631
name: hemolytic anemia
comment: doid/symp duplicate
is_a: SYMP:0000208 ! anemia

[Term]
id: SYMP:0000632
name: hip pain
def: "A joint pain that is characterized by a pain situated, or occurring, in or around the hip." [url:https\://medlineplus.gov/ency/article/003179.htm]
is_a: SYMP:0000064 ! joint pain

[Term]
id: SYMP:0000633
name: inflammatory low back pain
is_a: SYMP:0000006 ! backache

[Term]
id: SYMP:0000634
name: leukocytosis
is_a: SYMP:0019139 ! hemic system symptom

[Term]
id: SYMP:0000635
name: low backache
synonym: "low back pain" EXACT []
is_a: SYMP:0000006 ! backache

[Term]
id: SYMP:0000636
name: maculopapular rash
def: "A rash characterized by papule(s), which are a raised area of the skin and macule(s), which are a flat red area of the skin." [url:https\://www.webmd.com/skin-problems-and-treatments/what-is-maculopapular-rash]
is_a: SYMP:0000487 ! rash

[Term]
id: SYMP:0000637
name: opisthotonus
is_a: SYMP:0000183 ! muscle symptom

[Term]
id: SYMP:0000638
name: papular rash
def: "A rash characterized by papule(s), which are a raised area of the skin." [url:https\://www.webmd.com/skin-problems-and-treatments/what-is-maculopapular-rash]
is_a: SYMP:0000487 ! rash

[Term]
id: SYMP:0000639
name: rectorrhagia
synonym: "rectal bleeding" EXACT []
is_a: SYMP:0000459 ! digestive system symptom

[Term]
id: SYMP:0000640
name: ankle rash
def: "A rash characterized by an inflammatory reaction of the skin on the ankles." [url:https\://www.healthgrades.com/right-care/skin-hair-and-nails/ankle-rash]
synonym: "redness of ankle" EXACT []
is_a: SYMP:0000487 ! rash

[Term]
id: SYMP:0000641
name: renal involvement
is_a: SYMP:0000486 ! urinary system symptom

[Term]
id: SYMP:0000642
name: obsolete respiratory distress
is_obsolete: true

[Term]
id: SYMP:0000643
name: respiratory failure
def: "A respiratory system and chest symptom that is characterized by a difficulty to breathe on one's own and develops when the lungs cannot get enough oxygen into the blood." [url:https\://www.nhlbi.nih.gov/health/respiratory-failure]
comment: doid/symp duplicate - reviewed 10/2022, both DO & SYMP
synonym: "respiratory dysfunction" EXACT []
is_a: SYMP:0000514 ! respiratory system and chest symptom

[Term]
id: SYMP:0000644
name: ruffled feather
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000645
name: obsolete ankle swelling
is_obsolete: true

[Term]
id: SYMP:0000646
name: synovitis
def: "Synovitis is a joint inflammation characterized by an inflammation of a synovial membrane usually with pain and swelling of the joint." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=synovitis]
comment: doid/symp duplicate
is_a: SYMP:0000313 ! joint inflammation

[Term]
id: SYMP:0000647
name: tache noire
def: "A skin ulcer that is characterized by a a small dark-centered ulcer that appears at the site of a tick bite and is the primary lesion of boutonneuse fever." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=tache%20noire]
is_a: SYMP:0000136 ! skin ulcer

[Term]
id: SYMP:0000648
name: tenesmus
is_a: SYMP:0000459 ! digestive system symptom

[Term]
id: SYMP:0000649
name: terminal ileitis
is_a: SYMP:0000459 ! digestive system symptom

[Term]
id: SYMP:0000650
name: thick white exudate on tongue
is_a: SYMP:0000386 ! mouth symptom

[Term]
id: SYMP:0000651
name: discharge
is_a: SYMP:0000567 ! general symptom

[Term]
id: SYMP:0000652
name: wound discharge
is_a: SYMP:0000651 ! discharge

[Term]
id: SYMP:0000653
name: yellow dropping
is_a: SYMP:0000146 ! feces and droppings symptom

[Term]
id: SYMP:0000654
name: irritability
def: "A behavioral symptom that is characterized by a quick excitability to annoyance, impatience, or anger." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=irritability]
synonym: "Inconsolability" EXACT []
is_a: SYMP:0019182 ! behavioral symptom

[Term]
id: SYMP:0000655
name: mouth bleeding
is_a: SYMP:0000386 ! mouth symptom

[Term]
id: SYMP:0000656
name: pale mucous membrane
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000657
name: ischemic necrosis of jejunum
is_a: SYMP:0000725 ! necrosis of jejunum

[Term]
id: SYMP:0000658
name: extraocular muscles paralysis
is_a: SYMP:0000030 ! paralysis

[Term]
id: SYMP:0000659
name: pareses
def: "A paralysis that is charachterized by a slight or partial paralysis." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=pareses]
synonym: "partial paralysis" EXACT []
is_a: SYMP:0000030 ! paralysis

[Term]
id: SYMP:0000660
name: purpuric rash
def: "A rash characterized by a red or purple hued small spots of blood appear on the skin caused by conditions that result in blood leaking into the skin and other body surfaces that does not fade when pressed upon." [url:https\://en.wikipedia.org/wiki/Purpura, url:https\://patient.info/allergies-blood-immune/blood-clotting-tests/purpuric-rashes]
is_a: SYMP:0000487 ! rash

[Term]
id: SYMP:0000661
name: recumbency
is_a: SYMP:0000891 ! musculoskeletal system symptom

[Term]
id: SYMP:0000662
name: shakes
def: "Shakes is a general symptom characterized by a condition of trembling." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=shakes]
synonym: "trembling" EXACT []
is_a: SYMP:0000567 ! general symptom

[Term]
id: SYMP:0000663
name: uncoordinated gait
is_a: SYMP:0000891 ! musculoskeletal system symptom

[Term]
id: SYMP:0000664
name: yellow exudate from nose
is_a: SYMP:0000388 ! nose symptom

[Term]
id: SYMP:0000665
name: yellow exudate from eyes
is_a: SYMP:0019163 ! eye symptom

[Term]
id: SYMP:0000666
name: abnormal behavior
def: "A behavioral symptom that is characterized by behavior that is atypical or statistically uncommon within a particular culture, or that is maladaptive, or detrimental to an individual, or those around that individual." [url:https\://www.betterhelp.com/advice/behavior/what-is-abnormal-behavior/]
is_a: SYMP:0019182 ! behavioral symptom

[Term]
id: SYMP:0000667
name: obsolete heart rhythm symptom
is_obsolete: true
replaced_by: SYMP:0000287

[Term]
id: SYMP:0000668
name: obsolete abnormal heart rhythms
synonym: "abnormal heart beats" EXACT []
is_obsolete: true
replaced_by: SYMP:0000287

[Term]
id: SYMP:0000669
name: abnormal hemistanding
is_a: SYMP:0000189 ! postural reaction

[Term]
id: SYMP:0000670
name: abnormal hemiwalking
is_a: SYMP:0000189 ! postural reaction

[Term]
id: SYMP:0000671
name: sudden onset of fever
is_a: SYMP:0000613 ! fever

[Term]
id: SYMP:0000672
name: abscess
is_a: SYMP:0000567 ! general symptom

[Term]
id: SYMP:0000673
name: bradykinesia
def: "Bradykinesia is a hypokinesia characterized by an extreme slowness in the execution of movements and reflexes." [url:http\://en.wikipedia.org/wiki/Bradykinesia, url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=bradykinesia]
is_a: SYMP:0000858 ! hypokinesia

[Term]
id: SYMP:0000674
name: acute cranial nerve dysfunction
is_a: SYMP:0000336 ! neurological dysfunction

[Term]
id: SYMP:0000675
name: acute diarrhea
def: "Acute diarrhea is a diarrhea with either or both a rapid onset or a short course." [url:http\://en.wikipedia.org/wiki/Acute_%28medicine%29, url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=diarrhea]
comment: doid/symp duplicate
is_a: SYMP:0000570 ! diarrhea

[Term]
id: SYMP:0000676
name: acute enteritis
def: "Acute enteritis is a enteritis with either or both a rapid onset and a short course which is usually due to bacteria or virus." [url:http\://en.wikipedia.org/wiki/Acute_%28medicine%29, url:http\://en.wikipedia.org/wiki/Enteritis]
is_a: SYMP:0000039 ! enteritis

[Term]
id: SYMP:0000677
name: acute gastroenteritis
is_a: SYMP:0019159 ! gastroenteritis

[Term]
id: SYMP:0000678
name: acute mental dysfunction
def: "A nervous system symptom that is characterized by a severe and sudden onset of disturbance in the normal operation of one's cognition, emotional regulation, or behaviour." [url:https\://www.who.int/news-room/fact-sheets/detail/mental-disorders]
is_a: SYMP:0000480 ! nervous system symptom

[Term]
id: SYMP:0000679
name: acute dyspnea
def: "A dyspnea that is characterized by a severe and sudden onset." [url:https\://medlineplus.gov/ency/imagepages/18126.htm]
is_a: SYMP:0019153 ! dyspnea

[Term]
id: SYMP:0000680
name: acute weight loss
def: "A weight loss that is characterized by a severe and sudden onset." [url:https\://medlineplus.gov/ency/imagepages/18126.htm]
is_a: SYMP:0000178 ! weight loss

[Term]
id: SYMP:0000681
name: aggressive behavior
def: "A behavioral symptom that is characterized by behavior aimed at harming a person, or animal, or damaging physical property." [url:https\://www.healthline.com/health/aggressive-behavior]
is_a: SYMP:0019182 ! behavioral symptom

[Term]
id: SYMP:0000682
name: altered mental status
def: "A nervous system symptom that is characterized by a host of presentations that include changes in cognition, mood, behavior, and/or level of arousal." [url:https\://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Psychiatry_Guide/787028/all/Altered_Mental_Status]
is_a: SYMP:0000480 ! nervous system symptom

[Term]
id: SYMP:0000683
name: obsolete tachypnoea
def: "Tachypnoea is a respiratory system and chest symptom characterized by an increased rate of respiration." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=tachypnoea]
is_obsolete: true
replaced_by: SYMP:0000603

[Term]
id: SYMP:0000684
name: bifrontal headache
is_a: SYMP:0000504 ! headache

[Term]
id: SYMP:0000685
name: brain cyst
is_a: SYMP:0000480 ! nervous system symptom

[Term]
id: SYMP:0000686
name: chronic cough
def: "A cough that is characterized by an explosive expulsion of air from the lungs acting as a protective mechanism to clear the air passages or as a symptom of pulmonary disturbance marked by long duration, by frequent recurrence over a long time, and often by slowly progressing seriousness." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=chronic]
is_a: SYMP:0000614 ! cough

[Term]
id: SYMP:0000687
name: obsolete chronic fatigue syndrome
def: "Chronic fatigue syndrome is a fatigue characterized by a disorder of uncertain cause that is characterized by persistent profound fatigue usually accompanied by impairment in short-term memory or concentration, sore throat, tender lymph nodes, muscle or joint pain, and headache unrelated to any preexisting medical condition and that typically has an onset at about 30 years of age." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=chronic%20fatigue%20syndrome]
is_obsolete: true

[Term]
id: SYMP:0000688
name: circling movement
def: "An abnormal involuntary movement that is characterized by an inability to walk in a straight line." [url:https\://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434216/]
is_a: SYMP:0000594 ! abnormal involuntary movement

[Term]
id: SYMP:0000689
name: cramp
is_a: SYMP:0000567 ! general symptom

[Term]
id: SYMP:0000690
name: cranial nerve palsies
is_a: SYMP:0019163 ! eye symptom

[Term]
id: SYMP:0000691
name: cytopenia
is_a: SYMP:0019139 ! hemic system symptom

[Term]
id: SYMP:0000692
name: low blood pressure
is_a: SYMP:0020063 ! blood pressure

[Term]
id: SYMP:0000693
name: decreased facial sensation
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000694
name: decreased jaw tone
is_a: SYMP:0000891 ! musculoskeletal system symptom

[Term]
id: SYMP:0000695
name: decreased milk production
def: "A nutrition, metabolism, and development symptom that is characterized by a decrease in the production of milk in breastfeeding mothers." [url:https\://www.chop.edu/pages/low-milk-supply, url:https\://www.thewomens.org.au/health-information/breastfeeding/breastfeeding-problems/low-milk-supply]
is_a: SYMP:0000473 ! nutrition, metabolism, and development symptom

[Term]
id: SYMP:0000696
name: decreased motor response
is_a: SYMP:0000480 ! nervous system symptom

[Term]
id: SYMP:0000697
name: decreased pharyngeal tone
is_a: SYMP:0000385 ! throat symptom

[Term]
id: SYMP:0000698
name: decreased sucking
def: "A feeding difficulties and mismanagement that is characterized by a decrease in muscle coordination to form a suck response so that the child can ingest milk." [url:https\://adoption.umn.edu/sucking-problems]
is_a: SYMP:0000522 ! feeding difficulties and mismanagement

[Term]
id: SYMP:0000699
name: deltoid muscle weakness
is_a: SYMP:0000094 ! muscle weakness

[Term]
id: SYMP:0000700
name: diminished spontaneous movement
is_a: SYMP:0000480 ! nervous system symptom

[Term]
id: SYMP:0000701
name: nasal discharge
is_a: SYMP:0000388 ! nose symptom

[Term]
id: SYMP:0000702
name: distended loops of intestines on rectal
is_a: SYMP:0000459 ! digestive system symptom

[Term]
id: SYMP:0000703
name: droopy ears
is_a: SYMP:0000392 ! ear symptom

[Term]
id: SYMP:0000704
name: dysphonia
is_a: SYMP:0000559 ! voice disturbance

[Term]
id: SYMP:0000705
name: expressive aphasia
def: "An aphasia that is characterized by damage to, or a developmental issues in, the anterior regions of the brain, including (but not limited to) the left inferior frontal region known as Broca's area. Sufferers of this form of aphasia exhibit the common problem of agrammatism. For them, speech is difficult to initiate, non-fluent, labored, and halting." [url:http\://en.wikipedia.org/wiki/Expressive_aphasia]
synonym: "agrammatic aphasia" EXACT []
synonym: "Broca's aphasia" EXACT []
is_a: SYMP:0000508 ! aphasia

[Term]
id: SYMP:0000706
name: facial weakness
is_a: SYMP:0000387 ! head symptom

[Term]
id: SYMP:0000707
name: flaccid muscle tone
is_a: SYMP:0000183 ! muscle symptom

[Term]
id: SYMP:0000708
name: obsolete gas production
is_obsolete: true
replaced_by: SYMP:0000509

[Term]
id: SYMP:0000709
name: granulomatous inflammation
is_a: SYMP:0000061 ! inflammation

[Term]
id: SYMP:0000710
name: head pressing
is_a: SYMP:0000387 ! head symptom

[Term]
id: SYMP:0000711
name: hind limb paralysis
is_a: SYMP:0000030 ! paralysis

[Term]
id: SYMP:0000712
name: infertility
def: "A reproductive system symptom that is characterized the biological inability of a man or a woman to contribute to conception; or, the state of a woman who is unable to carry a pregnancy to full term." [url:http\://en.wikipedia.org/wiki/Infertility]
comment: doid/symp duplicate
is_a: SYMP:0000196 ! reproductive system symptom

[Term]
id: SYMP:0000713
name: inability to lie flat
is_a: SYMP:0000891 ! musculoskeletal system symptom

[Term]
id: SYMP:0000714
name: intraretinal hemorrhage
is_a: SYMP:0019163 ! eye symptom

[Term]
id: SYMP:0000715
name: skin desquamation
def: "A skin and integumentary tissue symptom that is characterized by the peeling off of skin in the form of scales." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=desquamation]
is_a: SYMP:0020048 ! skin peeling

[Term]
id: SYMP:0000716
name: swelling symptom
is_a: SYMP:0000567 ! general symptom

[Term]
id: SYMP:0000717
name: leg swelling
is_a: SYMP:0000716 ! swelling symptom

[Term]
id: SYMP:0000718
name: loss of consciousness
def: "A neurological and physiological symptom that is characterized by a state in which an individual lacks normal awareness of self and the surrounding environment and one's ability to remain awake, aware, and oriented is impaired." [url:https\://drwilderman.com/neurological-disorders/loss-of-consciousness/, url:https\://www.healthline.com/health/consciousness-decreased]
is_a: SYMP:0000410 ! neurological and physiological symptom

[Term]
id: SYMP:0000719
name: memory impairment
def: "A neurological and physiological symptom that is characterized by a diminished or reduced ability to remember things such as dates and names, and increased forgetfulness." [url:https\://www.merriam-webster.com/dictionary/impairment]
is_a: SYMP:0000410 ! neurological and physiological symptom

[Term]
id: SYMP:0000720
name: microangiopathic hemolytic anemia
is_a: SYMP:0000631 ! hemolytic anemia

[Term]
id: SYMP:0000721
name: moderate anemia
is_a: SYMP:0000208 ! anemia

[Term]
id: SYMP:0000722
name: moderate conjuctival injection
is_a: SYMP:0019163 ! eye symptom

[Term]
id: SYMP:0000723
name: multiple abscesses
is_a: SYMP:0000672 ! abscess

[Term]
id: SYMP:0000724
name: multiple organ failure
is_a: SYMP:0000567 ! general symptom

[Term]
id: SYMP:0000725
name: necrosis of jejunum
is_a: SYMP:0000459 ! digestive system symptom

[Term]
id: SYMP:0000726
name: painful reginal lymphadenopathy
is_a: SYMP:0019142 ! lymphadenopathy

[Term]
id: SYMP:0000727
name: palate weakness
is_a: SYMP:0000386 ! mouth symptom

[Term]
id: SYMP:0000728
name: partial hind limb paralysis
is_a: SYMP:0000711 ! hind limb paralysis

[Term]
id: SYMP:0000729
name: pulmonary consolidation
def: "A respiratory system and chest symptom that is characterized by a region of normally compressible lung tissue that has filled with liquid instead of air." [url:https\://en.wikipedia.org/wiki/Pulmonary_consolidation]
is_a: SYMP:0000514 ! respiratory system and chest symptom

[Term]
id: SYMP:0000730
name: rapid respiration
def: "A respiratory abnormality that is characterized by an increased breathing rate, with more than 20 breaths per minute in an adult, while in children, the number of breaths per minute can be a higher resting rate than seen in adults." [url:https\://www.healthline.com/health/rapid-shallow-breathing#What-is-tachypnea?]
is_a: SYMP:0000598 ! respiratory abnormality

[Term]
id: SYMP:0000731
name: renal failure
def: "A urinary system symptom that is characterized by a loss of excretory function in one or both kidneys, leading to retention of nitrogenous waste products from the blood." [url:https\://www.ncbi.nlm.nih.gov/books/NBK519012/]
is_a: SYMP:0000486 ! urinary system symptom

[Term]
id: SYMP:0000732
name: sudden ataxis
is_a: SYMP:0000005 ! ataxia

[Term]
id: SYMP:0000733
name: sternocleidomastoid weakness
is_a: SYMP:0000094 ! muscle weakness

[Term]
id: SYMP:0000734
name: obsolete stroke
def: "A nervous system symptom that is characterized by a sudden diminution or loss of consciousness, sensation, and voluntary motion caused by rupture or obstruction (as by a clot) of a blood vessel of the brain." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=stroke]
comment: doid/symp duplicate - reviewed 10/2022 & determined to be a disease
synonym: "apoplexy" EXACT []
synonym: "brain attack" EXACT []
synonym: "cerebral accident" EXACT []
synonym: "cerebrovascular accident" EXACT []
is_obsolete: true
replaced_by: SYMP:0020056

[Term]
id: SYMP:0000735
name: obsolete suppurative pneumonia
def: "A pneumonia that is characterized by the formation of pus and destruction of pulmonary tissue; abscess formation may occur." [url:https\://medical-dictionary.thefreedictionary.com/suppurative+pneumonia]
comment: reviewed 10/2022 & determined to be a disease
is_obsolete: true
replaced_by: SYMP:0020059

[Term]
id: SYMP:0000736
name: lymph gland swelling
is_a: SYMP:0000716 ! swelling symptom

[Term]
id: SYMP:0000737
name: respiratory tract mucosa ulcer
def: "A respiratory system and chest symptom that is characterized by an ulceration (dying and sloughing) of the bronchial or bronchiolar epithelium, exposing the underlying basement membrane." [url:https\://medical-dictionary.thefreedictionary.com/respiratory+mucosa, url:https\://ntp.niehs.nih.gov/nnl/respiratory/lung/ulcer/index.htm]
is_a: SYMP:0000514 ! respiratory system and chest symptom

[Term]
id: SYMP:0000738
name: yellowish green diarrhea
is_a: SYMP:0000570 ! diarrhea

[Term]
id: SYMP:0000739
name: bronchopulmonary bleeding
def: "A respiratory system and chest symptom that is characterized by bleeding (hemorrhage) in either or both the bronchi and the lungs." [url:https\://www.merriam-webster.com/medical/bronchopulmonary]
is_a: SYMP:0000514 ! respiratory system and chest symptom

[Term]
id: SYMP:0000740
name: genitourinary hemorrhage
is_a: SYMP:0000486 ! urinary system symptom

[Term]
id: SYMP:0000741
name: nasal bleeding
is_a: SYMP:0000388 ! nose symptom

[Term]
id: SYMP:0000742
name: gum bleeding
def: "Gum bleeding is a mouth symptom characterized by a copious discharge of blood from the blood vessels of the mucosal tissue that lies over the alveolar bone." [url:http\://en.wikipedia.org/wiki/Gingival, url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=hemorrhage]
synonym: "gingival hemorrhage" EXACT []
is_a: SYMP:0000655 ! mouth bleeding

[Term]
id: SYMP:0000743
name: blotchy red rash
is_a: SYMP:0000487 ! rash

[Term]
id: SYMP:0000744
name: cervical lymphadenopathy
is_a: SYMP:0019142 ! lymphadenopathy

[Term]
id: SYMP:0000745
name: change in body sensation
is_a: SYMP:0000567 ! general symptom

[Term]
id: SYMP:0000746
name: enanthem
def: "A skin and integumentary tissue symptom that is characterized by an eruption on a mucous surface." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=enanthem]
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000747
name: extreme prostration
is_a: SYMP:0000116 ! prostration

[Term]
id: SYMP:0000748
name: facial edema
def: "An adema that is characterized by an abnormal excess accumulation of serous fluid in connective tissue of the face." [url:https\://angletoner.com/facial-swelling/]
synonym: "facial swelling" EXACT []
is_a: SYMP:0000538 ! edema

[Term]
id: SYMP:0000749
name: hemodynamic instability
is_a: SYMP:0019139 ! hemic system symptom

[Term]
id: SYMP:0000750
name: hemorrhage into mucous membrane
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000751
name: hemorrhage into skin
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000752
name: herpetic lesion on upper lip
is_a: SYMP:0000386 ! mouth symptom

[Term]
id: SYMP:0000753
name: intense anxiety
is_a: SYMP:0000412 ! anxiety

[Term]
id: SYMP:0000754
name: severe chest pain
synonym: "intense chest pain" EXACT []
is_a: SYMP:0000576 ! chest pain

[Term]
id: SYMP:0000755
name: intense toxemia
is_a: SYMP:0019149 ! toxemia

[Term]
id: SYMP:0000756
name: menorrhagia
def: "A reproductive system symptom that is characterized an abnormally profuse menstrual flow." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=menorrhagia]
is_a: SYMP:0000196 ! reproductive system symptom

[Term]
id: SYMP:0000757
name: mild conjunctivitis
is_a: SYMP:0000128 ! conjunctivitis

[Term]
id: SYMP:0000758
name: neurological alteration
is_a: SYMP:0000480 ! nervous system symptom

[Term]
id: SYMP:0000759
name: parotid pain
def: "A pain that is characterized by a pain situated, or occurring, in the parotid gland, which is a salivary gland located in front of the ears. (Additional salivary glands include the submandibular and sublingual glands.) Pain is attributed to swelling of the gland." [url:https\://en.wikipedia.org/wiki/Parotid_gland, url:https\://en.wikipedia.org/wiki/Salivary_gland, url:https\://myhealth.alberta.ca/Health/aftercareinformation/pages/conditions.aspx?hwid=zp4169]
synonym: "salivary gland pain" EXACT []
is_a: SYMP:0000099 ! pain

[Term]
id: SYMP:0000760
name: petechiae
def: "A skin and integumentary tissue symptom that is characterized by a minute reddish or purplish spot containing blood that appears in skin or mucous membrane as a result of localized hemorrhage." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=petechiae]
synonym: "petechial rash" EXACT []
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000761
name: extracellular fluid alteration
is_a: SYMP:0000567 ! general symptom

[Term]
id: SYMP:0000762
name: excess lymphocytes in cerebrospinal fluid
is_a: SYMP:0000761 ! extracellular fluid alteration

[Term]
id: SYMP:0000763
name: renal alteration
is_a: SYMP:0000486 ! urinary system symptom

[Term]
id: SYMP:0000764
name: retrobulbar pain
def: "A pain that is characterized by a pain situated, or occurring, behind the eyeball." [url:https\://www.merriam-webster.com/medical/retrobulbar]
is_a: SYMP:0000099 ! pain

[Term]
id: SYMP:0000765
name: sensory disturbance
is_a: SYMP:0000567 ! general symptom

[Term]
id: SYMP:0000766
name: slow pulse
is_a: SYMP:0000567 ! general symptom

[Term]
id: SYMP:0000767
name: subconjunctival bleeding
is_a: SYMP:0019163 ! eye symptom

[Term]
id: SYMP:0000768
name: testicular pain
def: "A pain that is characterized by a pain in, or about, a testis (testicle) or testes. Testicular pain can be caused by nerve damage, sexually transmitted infections, gangrene, swelling, hernia, kidney stones, inflammation, enlarged veins, fluid in the testicle, or a severe condition known as testicular torsion." [url:https\://www.healthline.com/health/testicle-pain]
is_a: SYMP:0000099 ! pain

[Term]
id: SYMP:0000769
name: vascular alteration
is_a: SYMP:0000528 ! cardiovascular system symptom

[Term]
id: SYMP:0000770
name: pelvic symptom
is_a: SYMP:0000461 ! abdominal symptom

[Term]
id: SYMP:0000771
name: pelvic swelling
xref: ICD9CM_2005:789.3
is_a: SYMP:0000770 ! pelvic symptom

[Term]
id: SYMP:0000772
name: pelvic mass
xref: ICD9CM_2005:789.3
is_a: SYMP:0000770 ! pelvic symptom

[Term]
id: SYMP:0000773
name: pelvic lump
xref: ICD9CM_2005:789.3
is_a: SYMP:0000770 ! pelvic symptom

[Term]
id: SYMP:0000774
name: generalized pelvic lump
is_a: SYMP:0000773 ! pelvic lump

[Term]
id: SYMP:0000775
name: right lower quadrant pelvic lump
is_a: SYMP:0000773 ! pelvic lump

[Term]
id: SYMP:0000776
name: epigastric pelvic lump
is_a: SYMP:0000773 ! pelvic lump

[Term]
id: SYMP:0000777
name: left lower quadrant pelvic lump
is_a: SYMP:0000773 ! pelvic lump

[Term]
id: SYMP:0000778
name: left upper quadrant pelvic lump
is_a: SYMP:0000773 ! pelvic lump

[Term]
id: SYMP:0000779
name: right upper quadrant pelvic lump
is_a: SYMP:0000773 ! pelvic lump

[Term]
id: SYMP:0000780
name: multiple sites pelvic lump
is_a: SYMP:0000773 ! pelvic lump

[Term]
id: SYMP:0000781
name: periumbilic pelvic lump
is_a: SYMP:0000773 ! pelvic lump

[Term]
id: SYMP:0000782
name: right upper quadrant pelvic mass
is_a: SYMP:0000772 ! pelvic mass

[Term]
id: SYMP:0000783
name: left lower quadrant pelvic mass
is_a: SYMP:0000772 ! pelvic mass

[Term]
id: SYMP:0000784
name: epigastric pelvic mass
is_a: SYMP:0000772 ! pelvic mass

[Term]
id: SYMP:0000785
name: left upper quadrant pelvic mass
is_a: SYMP:0000772 ! pelvic mass

[Term]
id: SYMP:0000786
name: generalized pelvic mass
is_a: SYMP:0000772 ! pelvic mass

[Term]
id: SYMP:0000787
name: periumbilic pelvic mass
is_a: SYMP:0000772 ! pelvic mass

[Term]
id: SYMP:0000788
name: multiple sites pelvic mass
is_a: SYMP:0000772 ! pelvic mass

[Term]
id: SYMP:0000789
name: right lower quadrant pelvic mass
is_a: SYMP:0000772 ! pelvic mass

[Term]
id: SYMP:0000790
name: multiple sites pelvic swelling
is_a: SYMP:0000771 ! pelvic swelling

[Term]
id: SYMP:0000791
name: generalized pelvic swelling
is_a: SYMP:0000771 ! pelvic swelling

[Term]
id: SYMP:0000792
name: epigastric pelvic swelling
is_a: SYMP:0000771 ! pelvic swelling

[Term]
id: SYMP:0000793
name: left lower quadrant pelvic swelling
is_a: SYMP:0000771 ! pelvic swelling

[Term]
id: SYMP:0000794
name: left upper quadrant pelvic swelling
is_a: SYMP:0000771 ! pelvic swelling

[Term]
id: SYMP:0000795
name: periumbilic pelvic swelling
is_a: SYMP:0000771 ! pelvic swelling

[Term]
id: SYMP:0000796
name: right lower quadrant pelvic swelling
is_a: SYMP:0000771 ! pelvic swelling

[Term]
id: SYMP:0000797
name: right upper quadrant pelvic swelling
is_a: SYMP:0000771 ! pelvic swelling

[Term]
id: SYMP:0000798
name: abdominal mass
xref: ICD9CM_2005:789.3
xref: UMLS_CUI:C0476310
is_a: SYMP:0000461 ! abdominal symptom

[Term]
id: SYMP:0000799
name: abdominal lump
is_a: SYMP:0000461 ! abdominal symptom

[Term]
id: SYMP:0000800
name: left upper quadrant abdominal mass
is_a: SYMP:0000798 ! abdominal mass

[Term]
id: SYMP:0000801
name: left lower quadrant abdominal mass
is_a: SYMP:0000798 ! abdominal mass

[Term]
id: SYMP:0000802
name: epigastric abdominal mass
is_a: SYMP:0000798 ! abdominal mass

[Term]
id: SYMP:0000803
name: multiple sites abdominal mass
is_a: SYMP:0000798 ! abdominal mass

[Term]
id: SYMP:0000804
name: generalized abdominal mass
is_a: SYMP:0000798 ! abdominal mass

[Term]
id: SYMP:0000805
name: periumbilic abdominal mass
is_a: SYMP:0000798 ! abdominal mass

[Term]
id: SYMP:0000806
name: right lower quadrant abdominal mass
is_a: SYMP:0000798 ! abdominal mass

[Term]
id: SYMP:0000807
name: right upper quadrant abdominal mass
is_a: SYMP:0000798 ! abdominal mass

[Term]
id: SYMP:0000808
name: multiple sites abdominal lump
is_a: SYMP:0000799 ! abdominal lump

[Term]
id: SYMP:0000809
name: periumbilic abdominal lump
is_a: SYMP:0000799 ! abdominal lump

[Term]
id: SYMP:0000810
name: epigastric abdominal lump
is_a: SYMP:0000799 ! abdominal lump

[Term]
id: SYMP:0000811
name: left upper quadrant abdominal lump
is_a: SYMP:0000799 ! abdominal lump

[Term]
id: SYMP:0000812
name: right lower quadrant abdominal lump
is_a: SYMP:0000799 ! abdominal lump

[Term]
id: SYMP:0000813
name: right upper quadrant abdominal lump
is_a: SYMP:0000799 ! abdominal lump

[Term]
id: SYMP:0000814
name: generalized abdominal lump
is_a: SYMP:0000799 ! abdominal lump

[Term]
id: SYMP:0000815
name: left lower quadrant abdominal lump
is_a: SYMP:0000799 ! abdominal lump

[Term]
id: SYMP:0000816
name: dysfunctions associated with arousal from sleep
xref: ICD9CM_2005:307.47
is_a: SYMP:0000566 ! sleep disturbance

[Term]
id: SYMP:0000817
name: inability to concentrate
is_a: SYMP:0000482 ! alteration of consciousness

[Term]
id: SYMP:0000818
name: localized superficial mass
xref: ICD9CM_2005:782.2
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000819
name: localized superficial swelling
xref: ICD9CM_2005:782.2
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000820
name: mass in chest
xref: ICD9CM_2005:786.6
is_a: SYMP:0000514 ! respiratory system and chest symptom

[Term]
id: SYMP:0000821
name: swelling in chest
is_a: SYMP:0000514 ! respiratory system and chest symptom

[Term]
id: SYMP:0000822
name: chronic enteritis
def: "Chronic enteritis is a enteritis with slow progress, long duration, or frequent recurrence which can be due to Crohn's disease, giardiasis, tuberculosis, coeliac disease, or rarely due to Whipple's disease." [url:http\://en.wikipedia.org/wiki/Enteritis, url:http\://www.rootsweb.ancestry.com/~vapage2/deathcauses.htm]
is_a: SYMP:0000039 ! enteritis

[Term]
id: SYMP:0000823
name: sinus bradycardia
def: "Sinus bradycardia is a bradycardia where the sinus rhythm is abnormally slow bradycardia consisting of a sinus rhythm at a rate lower than 60 beats per minute." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=sinus%20bradycardia]
is_a: SYMP:0000231 ! bradycardia

[Term]
id: SYMP:0000824
name: junctional tachycardia
def: "Junctional tachycardia is a tachycardia associated with the generation of impulses in a locus in the region of the atrioventricular node." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=junctional%20tachycardia]
is_a: SYMP:0000529 ! tachycardia

[Term]
id: SYMP:0000825
name: paroxysmal tachycardia
def: "Paroxysmal tachycardia is a tachycardia that begins and ends abruptly and that is initiated by a premature supraventricular beat originating in the atrium or in the atrioventricular node or bundle of His or by a premature ventricular beat." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=paroxysmal%20tachycardia]
is_a: SYMP:0000529 ! tachycardia

[Term]
id: SYMP:0000826
name: sinus tachycardia
def: "Sinus tachycardia is a tachychardia characterized by an abnormally rapid sinus rhythm specifically a sinus rhythm at a rate greater than 100 beats per minute." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=sinus%20tachycardia]
is_a: SYMP:0000529 ! tachycardia

[Term]
id: SYMP:0000827
name: ventricular tachycardia
def: "A tachycardia that is associated with the generation of improper electrical impulses within the ventricles, characterized by an electrocardiogram showing a rate of greater than 120 BPM and three or more wide QRS complexes in a row." [url:https\://en.wikipedia.org/wiki/Ventricular_tachycardia]
synonym: "V-tach" EXACT []
synonym: "VT" EXACT []
is_a: SYMP:0000529 ! tachycardia

[Term]
id: SYMP:0000828
name: sore eyes
def: "Sore eyes is a eye symptom characterized by an inflammation of the thin covering of the eyeball and the inner eyelid brought about by a viral infection which may be highly contagious." [url:http\://www.doh.gov.ph/faqs/sore_eyes]
is_a: SYMP:0019163 ! eye symptom

[Term]
id: SYMP:0000829
name: neck pain
def: "A pain that is characterized by an unpleasant sensation localized in the neck that usually indicates the body is threatened or damaged. The sensation may be sharp or dull, short-lived or chronic, intermittent or continual." [url:http\://www.nationalpainfoundation.org/MyTreatment/articles/Cancer_PainDefinitions.asp]
is_a: SYMP:0000099 ! pain

[Term]
id: SYMP:0000830
name: phantom pain
def: "A pain that is characterized by a painful sensation that is perceived to originate in the amputated portion of the extremety. Patients may have localized pain that originates in the stump." [url:http\://www.nationalpainfoundation.org/MyTreatment/articles/Cancer_PainDefinitions.asp]
is_a: SYMP:0000099 ! pain

[Term]
id: SYMP:0000831
name: nociceptive pain
def: "A pain that is characterized by originating from other than the peripheral and central nervous systems, and which is caused by activation of nociceptive fibers." [url:http\://www.nationalpainfoundation.org/MyTreatment/articles/Cancer_PainDefinitions.asp]
is_a: SYMP:0000099 ! pain

[Term]
id: SYMP:0000832
name: neuropathic pain
def: "A pain that is characterized by being experienced by cancer patients and which is caused by radiotherapy or chemotherapy damage to nerves, when cancer invades or compresses nerves, or when, during cancer treatment. This type of pain is typically described as burning, electrical, or strange feeling." [url:http\://www.nationalpainfoundation.org/MyTreatment/articles/Cancer_PainDefinitions.asp]
is_a: SYMP:0000099 ! pain

[Term]
id: SYMP:0000833
name: visceral pain
def: "A pain that is characterized by originating from organ tissues of the thorax, abdomen, or pelvis.  It characterizes as deep, vague, and difficult to locate pain, that radiates away from the affected organ." [url:http\://www.nationalpainfoundation.org/MyTreatment/articles/Cancer_PainDefinitions.asp]
is_a: SYMP:0000099 ! pain

[Term]
id: SYMP:0000834
name: hypoesthesia
def: "A sensation perception that is characterized by a reduced sense of touch or sensation, or a partial loss of sensitivity to sensory stimuli." [url:https\://en.wikipedia.org/wiki/Hypoesthesia]
synonym: "numbness" EXACT []
is_a: SYMP:0000892 ! sensation perception

[Term]
id: SYMP:0000835
name: hypoalgesia
def: "A sensation perception that is characterized by a diminished sensitivity to painful stimulation." [url:http\://www.nationalpainfoundation.org/MyTreatment/articles/Cancer_PainDefinitions.asp]
is_a: SYMP:0000892 ! sensation perception

[Term]
id: SYMP:0000836
name: hyperalgesia
def: "A sensation perception that is characterized by an increased response to a painful stimulus." [url:http\://www.nationalpainfoundation.org/MyTreatment/articles/Cancer_PainDefinitions.asp]
is_a: SYMP:0000892 ! sensation perception

[Term]
id: SYMP:0000837
name: chronic pain
def: "A pain that is characterized by ranging from mild to severe and which continues beyond the expected healing phase." [url:http\://www.nationalpainfoundation.org/MyTreatment/articles/Cancer_PainDefinitions.asp]
is_a: SYMP:0000099 ! pain

[Term]
id: SYMP:0000838
name: breakthrough pain
def: "A pain that is characterized by occurring with movement and is not controlled by a scheduled pain medication regimen, such that the pain breaks through the current regimen. This is usually referred to in the context of a short and long acting opioid, the short acting opioid being used to treat the breakthrough pain." [url:http\://www.nationalpainfoundation.org/MyTreatment/articles/Cancer_PainDefinitions.asp]
is_a: SYMP:0000099 ! pain

[Term]
id: SYMP:0000839
name: acute pain
def: "A pain that is characterized by being severe but lasting a relatively short time." [url:http\://www.nationalpainfoundation.org/MyTreatment/articles/Cancer_PainDefinitions.asp]
synonym: "sudden pain" EXACT []
is_a: SYMP:0000099 ! pain

[Term]
id: SYMP:0000840
name: allodynia
def: "A pain that is characterized by a painful sensation with a normal, non-painful stimulation." [url:http\://www.nationalpainfoundation.org/MyTreatment/articles/Cancer_PainDefinitions.asp]
is_a: SYMP:0000099 ! pain

[Term]
id: SYMP:0000841
name: reactive hyperemia
def: "Reactive hyperemia is a hyperemia occuring due to the dilation of arteriolar smooth muscle to increase blood flow in response to a profound increase in blood flow to an organ after being occluded. There will be a shortage of oxygen and a build-up of metabolic waste." [url:http\://en.wikipedia.org/wiki/Hyperemia]
is_a: SYMP:0000299 ! hyperemia

[Term]
id: SYMP:0000842
name: active hyperemia
def: "Active hyperemia is a hyperemia occuring due to the dilation of arteriolar smooth muscle to increase blood flow in response to an increase in metabolism." [url:http\://en.wikipedia.org/wiki/Hyperemia]
is_a: SYMP:0000299 ! hyperemia

[Term]
id: SYMP:0000843
name: functional hyperemia
def: "Functional hyperemia is a hyperemia occuring due to an increase in blood flow to a tissue due to the presence of metabolites and a change in general conditions." [url:http\://en.wikipedia.org/wiki/Hyperemia]
is_a: SYMP:0000299 ! hyperemia

[Term]
id: SYMP:0000844
name: face hyperemia
def: "Hyperemia of the face is a head symptom consisting of an excess of blood in the tissues of the face as from an increased flow of blood due to vasodilation." [url:http\://en.wikipedia.org/wiki/Hyperemia]
is_a: SYMP:0000387 ! head symptom

[Term]
id: SYMP:0000845
name: hyperemia of the neck
def: "Hyperemia of the neck is a neck symptom consisting of an excess of blood in the tissues of the neck as from an increased flow of blood due to vasodilation." [url:http\://en.wikipedia.org/wiki/Hyperemia]
is_a: SYMP:0000384 ! neck symptom

[Term]
id: SYMP:0000846
name: chest hyperemia
def: "Hyperemia of the chest is a cardiovascular system symptom consisting of an excess of blood in the tissues of the chest as from an increased flow of blood due to vasodilation." [url:http\://en.wikipedia.org/wiki/Hyperemia]
is_a: SYMP:0000528 ! cardiovascular system symptom

[Term]
id: SYMP:0000847
name: spastic paralysis
def: "A paralysis that is characterized by a tonic spasm of the affected muscles and with increased tendon reflexes." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=spastic%20paralysis]
is_a: SYMP:0000030 ! paralysis

[Term]
id: SYMP:0000848
name: motor paralysis
def: "A paralysis that is characterized by a complete or partial loss of function the voluntary muscles." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=motor%20paralysis]
is_a: SYMP:0000030 ! paralysis

[Term]
id: SYMP:0000849
name: stillbirth
def: "A reproductive system symptom that is characterized by the birth of a dead fetus; in which  a fetus that has died in the uterus, or during labor, or delivery, exits a woman's body." [url:http\://en.wikipedia.org/wiki/Still_birth, url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=stillbirth]
is_a: SYMP:0000196 ! reproductive system symptom

[Term]
id: SYMP:0000850
name: congested sclera
def: "Congested sclera is a hyperemia characterized as the congestion of the vessels of the outer layer of the eye containing collagen and elastic fibers." [url:http\://en.wikipedia.org/wiki/Sclera]
is_a: SYMP:0000299 ! hyperemia

[Term]
id: SYMP:0000851
name: gross hematuria
def: "A hematuria that is characterized by the production of a visible redness in the urine." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=gross%20hematuria]
is_a: SYMP:0000040 ! hematuria

[Term]
id: SYMP:0000852
name: anuria
def: "A urinary system symptom that is characterized by the absence of, or by defective, urine excretion." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=anuria]
comment: doid/symp duplicate
xref: ICD9CM_2005:788.5
xref: UMLS_CUI:C0028962
xref: UMLS_ICD9CM_2005_AUI:A0243854
is_a: SYMP:0000486 ! urinary system symptom

[Term]
id: SYMP:0000853
name: stress incontinence
def: "A urinary incontinence that is characterized by an involuntary leakage of urine from the bladder accompanying physical activity (as in laughing, coughing, sneezing, or physical exercise) which places increased pressure on the abdomen." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=stress%20incontinence, url:https\://www.health.harvard.edu/bladder-and-bowel/types-of-urinary-incontinence]
is_a: SYMP:0000492 ! urinary incontinence

[Term]
id: SYMP:0000854
name: hypermenorrhea
def: "A menorrhagia that is characterized by an abnormally profuse or prolonged menstrual flow." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=hypermenorrhea]
is_a: SYMP:0000756 ! menorrhagia

[Term]
id: SYMP:0000855
name: metrorrhagia
def: "A menorrhagia that is characterized by an irregular uterine bleeding, especially between menstrual periods." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=metrorrhagia]
is_a: SYMP:0000756 ! menorrhagia

[Term]
id: SYMP:0000856
name: subjective vertigo
def: "A vertigo that is characterized by a sensation that one's body is revolving in space." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=subjective+vertigo]
is_a: SYMP:0000399 ! vertigo

[Term]
id: SYMP:0000857
name: objective vertigo
def: "A vertigo that is characterized by a sensation that the external world is revolving." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=objective+vertigo]
is_a: SYMP:0000399 ! vertigo

[Term]
id: SYMP:0000858
name: hypokinesia
def: "Hypokinesia is a musculoskeletal system  symptom characterized by the slow or diminished movement of body musculature. It may be associated with basal ganglia diseases; mental disorders; prolonged inactivity due to illness; experimental protocols used to evaluate the physiologic effects of immobility; and other conditions." [url:http\://en.wikipedia.org/wiki/Hypokinesia]
is_a: SYMP:0000891 ! musculoskeletal system symptom

[Term]
id: SYMP:0000859
name: rigidity hypokinesia
def: "Rigidity hypokinesia a type of hypokinesia described as the increase in muscle tension when moved by an outside force." [url:http\://en.wikipedia.org/wiki/Hypokinesia]
is_a: SYMP:0000858 ! hypokinesia

[Term]
id: SYMP:0000860
name: postural instability hypokinesia
def: "Postural instability hypokinesia is a hypokinesia described as a loss of ability to maintain an upright posture." [url:http\://en.wikipedia.org/wiki/Hypokinesia]
is_a: SYMP:0000858 ! hypokinesia

[Term]
id: SYMP:0000861
name: freezing hypokinesia
def: "Freezing hypokinesia is a hypkinesia where a person can not move their muscles how they want them to." [url:http\://en.wikipedia.org/wiki/Hypokinesia]
is_a: SYMP:0000858 ! hypokinesia

[Term]
id: SYMP:0000862
name: referred pain
def: "A pain that is characterized by pain which is subjectively localized in one region although it is due to irritation in another region." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=referred%20pain]
is_a: SYMP:0000099 ! pain

[Term]
id: SYMP:0000863
name: facial tremor
def: "Facial tremor is a head symptom characterized by a trembling or shaking of the muscles of the face usually from physical weakness, emotional stress, or disease, may be emphasized by the firm closure of the eyes, elevation of the eyebrows, or drawing down and outward of the corners of the mouth." [url:http\://books.google.com/books/pdf/Medical_Diagnosis_for_the_Student_and_Pr.pdf?id=NWOYzn2-_pcC&output=pdf&sig=ACfU3U01YhXqEIhGHVTFAnUinc9-Q8INRQ, url:http\://www.merriam-webster.com/dictionary/tremors]
is_a: SYMP:0000387 ! head symptom

[Term]
id: SYMP:0000864
name: lesions in oropharynx
is_a: SYMP:0000385 ! throat symptom

[Term]
id: SYMP:0000865
name: lesions in mouth
is_a: SYMP:0000386 ! mouth symptom

[Term]
id: SYMP:0000866
name: cervical edema
def: "Cervical edema is a neck symptom characterized by an abnormal excess accumulation of serous fluid in the soft tissue of the cervical area." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=edema]
is_a: SYMP:0000384 ! neck symptom

[Term]
id: SYMP:0000867
name: gastrointestinal bleeding
def: "A digestive system symptom characterized by bleeding from one or more of the areas of the digestive or gastrointestinal (GI) tract that includes the espophagus, stomach, small intestine, large intestine or colon, rectum and anus." [url:http\://www.nlm.nih.gov/medlineplus/gastrointestinalbleeding.html]
is_a: SYMP:0000459 ! digestive system symptom

[Term]
id: SYMP:0000868
name: breathing problems
def: "A respiratory abnormality that is characterized by a shortness of breath, a hard or uncomfortable intake of air, or the feeling that you're not getting enough air." [url:http\://www.nlm.nih.gov/medlineplus/breathingproblems.html]
is_a: SYMP:0000598 ! respiratory abnormality

[Term]
id: SYMP:0000869
name: nasal congestion
def: "A congestion that is characterized by a blockage of the nasal passages, usually due to the membranes lining the nose becoming swollen from inflamed blood vessels." [url:http\://en.wikipedia.org/wiki/Nasal_congestion]
is_a: SYMP:0000237 ! congestion

[Term]
id: SYMP:0000870
name: icteric eyes
def: "Icteric eyes is a eye symptom characterized by yellowed eyes due to bile or bilirubin accumulation." [url:http\://en.wikipedia.org/wiki/Jaundice, url:http\://www3.niaid.nih.gov/labs/aboutlabs/cmb/InfectiousDiseasePathogenesisSection/mouseNecropsy/necropsyTerms.htm]
is_a: SYMP:0019163 ! eye symptom

[Term]
id: SYMP:0000871
name: icteric mucous membrane
def: "A skin and integumentary tissue symptom that is characterized by yellowed mucous membranes due to bile or bilirubin accumulation." [url:http\://en.wikipedia.org/wiki/Jaundice]
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000872
name: icteric skin
def: "A skin and integumentary tissue symptom that is characterized by yellowed skin due to bile or bilirubin accumulation." [url:http\://en.wikipedia.org/wiki/Jaundice]
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000873
name: otitis
def: "Otitis is a ear symptom characterized as a general term for inflammation or infection of the ear, in both humans and other animals." [url:http\://en.wikipedia.org/wiki/Otitis]
is_a: SYMP:0000392 ! ear symptom

[Term]
id: SYMP:0000874
name: hematoma
def: "A skin and integumentary tissue symptom that is characterized by a mass of usually clotted blood that forms in a tissue, organ, or body space as a result of a broken blood vessel generally the result of hemorrhage, or more specifically, internal bleeding." [url:http\://en.wikipedia.org/wiki/Hematoma, url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=Hematomas]
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0000875
name: lameness
def: "Lameness is a musculoskeletal system symptom where a person is physically disabled as the result of having a body part and especially a limb so disabled as to impair freedom of movement." [url:http\://www.merriam-webster.com/dictionary/lame]
is_a: SYMP:0000891 ! musculoskeletal system symptom

[Term]
id: SYMP:0000876
name: pericardial effusion
def: "Pericardial effusion is a cardiovascular system symptom where there is an abnormal accumulation of fluid in the pericardial cavity." [url:http\://en.wikipedia.org/wiki/Pericardial_effusion]
comment: doid/symp duplicate
is_a: SYMP:0000528 ! cardiovascular system symptom

[Term]
id: SYMP:0000877
name: decreased tongue tone
is_a: SYMP:0000386 ! mouth symptom

[Term]
id: SYMP:0000878
name: transient fever
def: "A fever that is characterized by a rise of body temperature above the normal that is sustained for only a short period of time." [url:http\://en.wiktionary.org/wiki/fever, url:http\://en.wiktionary.org/wiki/transient]
is_a: SYMP:0000613 ! fever

[Term]
id: SYMP:0000879
name: low-grade fever
def: "A mild fever that is characterized by a fever that does not exceed 38.5 degrees Celsius (101.3 degrees Fahrenheit)." [url:http\://www.wrongdiagnosis.com/sym/low_grade_fever.htm]
synonym: "low grade fever" EXACT []
is_a: SYMP:0000881 ! mild fever
created_by: lschriml
creation_date: 2010-10-15T11:28:26Z

[Term]
id: SYMP:0000880
name: prolonged fever
def: "A fever that is characterized by as  persisting over a prolonged period of time." [url:http\://www.wrongdiagnosis.com/sym/prolonged_fever.htm]
is_a: SYMP:0000613 ! fever
created_by: lschriml
creation_date: 2010-10-15T11:28:26Z

[Term]
id: SYMP:0000881
name: mild fever
def: "A fever that is characterized by being mild in form." [url:http\://www.wrongdiagnosis.com/sym/mild_fever.htm]
is_a: SYMP:0000613 ! fever
created_by: lschriml
creation_date: 2010-10-15T11:28:26Z

[Term]
id: SYMP:0000882
name: high fever
def: "A fever that is characterized by an elevated temperature." [url:http\://www.wrongdiagnosis.com/sym/high_fever.htm]
is_a: SYMP:0000613 ! fever
created_by: lschriml
creation_date: 2010-10-15T11:28:26Z

[Term]
id: SYMP:0000883
name: very high fever
def: "A high fever that is characterized by extremely high temperatures." [url:http\://www.wrongdiagnosis.com/sym/very_high_fever.htm]
is_a: SYMP:0000882 ! high fever
created_by: lschriml
creation_date: 2010-10-15T11:28:26Z

[Term]
id: SYMP:0000884
name: obsolete recurrent fever
comment: The obsolete label is a best guess based on the addition of SYMP:0000884 as an alternative ID for SYMP:0000237 in revision 637 of the Gemina project SVN repository (https://sourceforge.net/p/gemina/code/637/tree//trunk/Gemina/ontologies/gemina_symptom.obo?diff=51796e7f5fcbc979b911aaf7:636). The original class was deprecated and removed before creation of that SVN repository (< 2007-08-09).
is_obsolete: true
replaced_by: SYMP:0000243

[Term]
id: SYMP:0000885
name: obsolete severe temperature increase
is_obsolete: true
created_by: lschriml
creation_date: 2010-10-15T11:28:26Z

[Term]
id: SYMP:0000886
name: hyperpyrexia
def: "A fever that is characterized by an extreme elevation of body temperature greater than, or equal to, 41.5 degrees Celsius (106.7 degrees Fahrenheit)." [url:http\://en.wikipedia.org/wiki/Fever]
is_a: SYMP:0000613 ! fever
created_by: lschriml
creation_date: 2010-10-15T11:38:55Z

[Term]
id: SYMP:0000887
name: Pel-Epstein fever
def: "A fever that is characterized by association with Hodgkin's lymphoma, where the fever alternates weekly from high to low." [url:http\://en.wikipedia.org/wiki/Fever]
is_a: SYMP:0000613 ! fever
created_by: lschriml
creation_date: 2010-10-15T11:40:07Z

[Term]
id: SYMP:0000888
name: continuous fever
def: "A fever that is characterized by a temperature remaining above normal throughout the day and which does not fluctuate more than 1 degree Celsius in 24 hours." [url:http\://en.wikipedia.org/wiki/Fever#Types]
synonym: "continued fever" RELATED []
is_a: SYMP:0000613 ! fever
created_by: lschriml
creation_date: 2010-10-15T11:42:19Z

[Term]
id: SYMP:0000889
name: remittent fever
def: "A fever that is characterized by a fever where the temperature remains above normal throughout the day and fluctuates more than 1 degree Celsius in 24 hours." [url:http\://en.wikipedia.org/wiki/Fever#Types]
is_a: SYMP:0000613 ! fever
created_by: lschriml
creation_date: 2010-10-15T11:42:19Z

[Term]
id: SYMP:0000890
name: relapsing fever
def: "A fever that is characterized by  body temperature periodically rising and falling." [url:https\://www.merckmanuals.com/professional/infectious-diseases/spirochetes/relapsing-fever]
comment: doid/symp duplicate
is_a: SYMP:0000613 ! fever
created_by: lschriml
creation_date: 2010-10-15T11:46:03Z

[Term]
id: SYMP:0000891
name: musculoskeletal system symptom
is_a: SYMP:0000462 ! symptom
created_by: lschriml
creation_date: 2010-10-15T11:48:05Z

[Term]
id: SYMP:0000892
name: sensation perception
def: "A nervous system symptom that is characterized by interpretation of the information perceived by sensory receptors." [url:http\://www.audiblox2000.com/sensation-perception.htm]
is_a: SYMP:0000480 ! nervous system symptom
created_by: lschriml
creation_date: 2010-10-15T11:54:30Z

[Term]
id: SYMP:0000893
name: hypotensive
def: "A low blood pressure characterized by or due to abnormally low blood pressure, especially in the arteries of the systemic circulation." [url:http\://en.wikipedia.org/wiki/Hypotension, url:http\://www.merriam-webster.com/medlineplus/hypotensive]
is_a: SYMP:0000692 ! low blood pressure
created_by: lschriml
creation_date: 2011-11-17T12:20:22Z

[Term]
id: SYMP:0000894
name: cold clammy skin
def: "A skin and integumentary tissue symptom that is characterized by cold, moist and sticky skin." [url:http\://www.merriam-webster.com/medlineplus/clammy]
is_a: SYMP:0000488 ! skin and integumentary tissue symptom
created_by: lschriml
creation_date: 2011-11-17T12:27:44Z

[Term]
id: SYMP:0000895
name: anaphylactic shock
def: "An acute allergic reaction to an antigen to which the body has become hypersensitive." [url:https\://en.wikipedia.org/wiki/Anaphylaxis]
synonym: "anaphylaxis" EXACT []
is_a: SYMP:0019138 ! immune system symptom

[Term]
id: SYMP:0000896
name: exophthalmos
def: "An abnormal protrusion or displacement of an eye or other body part." [url:https\://en.wikipedia.org/wiki/Exophthalmos, url:https\://www.merckmanuals.com/professional/eye-disorders/symptoms-of-ophthalmologic-disorders/proptosis, url:https\://www.nhs.uk/conditions/bulging-eyes/]
comment: doid/symp duplicate
synonym: "exophthalmia" EXACT []
synonym: "exophthalmus" EXACT []
synonym: "proptosis" EXACT []
is_a: SYMP:0019163 ! eye symptom

[Term]
id: SYMP:0000897
name: ventricular bradycardia
def: "A bradycardia associated with the generation of impules in the ventricles when impules from the atria fail to reach them, characterized by an electrocardiogram showing a heart rate below 50 BPM and a broad QRS complex." [url:https\://en.wikipedia.org/wiki/Ventricular_escape_beat]
synonym: "idioventricular rhythm" EXACT []
synonym: "ventricular escape rhythm" EXACT []
is_a: SYMP:0000231 ! bradycardia

[Term]
id: SYMP:0000898
name: cardiac fibrillation
def: "An arrhythmia characterized by rapid, irregular, and unsynchronized contraction of muscle fibers within the heart." [url:https\://en.wikipedia.org/wiki/Fibrillation]
is_a: SYMP:0000287 ! arrhythmia

[Term]
id: SYMP:0000899
name: ventricular fibrillation
def: "A cardiac fibrillation associated with quivering of the lower chambers of the heart, preventing blood from being pumped and causing cardiac arrest." [url:http\://www.heart.org/HEARTORG/Conditions/Arrhythmia/AboutArrhythmia/Ventricular-Fibrillation_UCM_324063_Article.jsp#.WvWbgFMvwnU]
synonym: "v-fib" EXACT []
is_a: SYMP:0000898 ! cardiac fibrillation

[Term]
id: SYMP:0000900
name: allergic reaction
def: "An immune system symptom that is characterized by sensitivities to substances called allergens." [url:https\://medlineplus.gov/ency/article/000005.htm]
is_a: SYMP:0019138 ! immune system symptom

[Term]
id: SYMP:0017795
name: hemic and immune system symptom
is_a: SYMP:0000462 ! symptom

[Term]
id: SYMP:0019138
name: immune system symptom
is_a: SYMP:0017795 ! hemic and immune system symptom

[Term]
id: SYMP:0019139
name: hemic system symptom
is_a: SYMP:0017795 ! hemic and immune system symptom

[Term]
id: SYMP:0019140
name: hematopoietic system symptom
is_a: SYMP:0017795 ! hemic and immune system symptom

[Term]
id: SYMP:0019141
name: lymphatic system symptom
is_a: SYMP:0019138 ! immune system symptom

[Term]
id: SYMP:0019142
name: lymphadenopathy
synonym: "adenopathy" EXACT []
is_a: SYMP:0000521 ! enlargement of lymph nodes

[Term]
id: SYMP:0019143
name: coagulopathy
is_a: SYMP:0019139 ! hemic system symptom

[Term]
id: SYMP:0019144
name: microangiopathy
is_a: SYMP:0019139 ! hemic system symptom

[Term]
id: SYMP:0019145
name: vomiting
def: "Vomiting is a digestive system symptom characterized by throwing up the stomach contents." [url:http\://www.merriam-webster.com/dictionary/vomiting]
synonym: "emesis" EXACT []
is_a: SYMP:0000459 ! digestive system symptom

[Term]
id: SYMP:0019146
name: hyponatremia
is_a: SYMP:0019139 ! hemic system symptom

[Term]
id: SYMP:0019147
name: hematemesis
def: "A vomiting where there is vomiting of blood." [url:http\://en.wikipedia.org/wiki/Hematemesis]
synonym: "bloody vomit" EXACT []
synonym: "haematemesis" EXACT []
synonym: "vomiting blood" EXACT []
is_a: SYMP:0019145 ! vomiting

[Term]
id: SYMP:0019148
name: septicemia
is_a: SYMP:0019139 ! hemic system symptom

[Term]
id: SYMP:0019149
name: toxemia
is_a: SYMP:0019139 ! hemic system symptom

[Term]
id: SYMP:0019150
name: obsolete pharyngitis
comment: doid/symp duplicate - reviewed 10/2022 & determined to be a disease
synonym: "pharynx inflammation" EXACT []
is_obsolete: true
replaced_by: SYMP:0020055

[Term]
id: SYMP:0019151
name: pulmonary edema
def: "A respiratory system and chest symptom that is characterized by an abnormal accumulation of fluid in the lungs." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=pulmonary%20edema]
comment: doid/symp duplicate
synonym: "oedematous lungs" EXACT []
is_a: SYMP:0000514 ! respiratory system and chest symptom

[Term]
id: SYMP:0019152
name: diaphoresis
def: "A sweat that is characterized by excessive sweating commonly associated with shock and other medical emergency conditions." [url:http\://en.wikipedia.org/wiki/Diaphoresis]
synonym: "profuse perspiration" EXACT []
is_a: SYMP:0019175 ! sweaty

[Term]
id: SYMP:0019153
name: dyspnea
def: "A respiratory abnormality that is characterized by difficult or labored respiration." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=dyspnea]
synonym: "breathing difficulty" EXACT []
synonym: "breathlessness" EXACT []
synonym: "difficulty breathing" EXACT []
synonym: "labored respiration" EXACT []
synonym: "shortness of breath" EXACT []
is_a: SYMP:0000598 ! respiratory abnormality

[Term]
id: SYMP:0019154
name: hemorrhagic mediastinitis
def: "A respiratory abnormality that is characterized by inflammation of the mediastinum (the chest cavity, which contains the heart, the thymus gland, some lymph nodes, and parts of the esophagus, aorta, thyroid, and parathyroid glands) as the result of bleeding." [url:https\://www.merckmanuals.com/home/lung-and-airway-disorders/pleural-and-mediastinal-disorders/mediastinitis]
is_a: SYMP:0000514 ! respiratory system and chest symptom

[Term]
id: SYMP:0019155
name: lymphadenitis
comment: doid/symp duplicate
is_a: SYMP:0019141 ! lymphatic system symptom

[Term]
id: SYMP:0019156
name: hematogenous
is_a: SYMP:0019139 ! hemic system symptom

[Term]
id: SYMP:0019158
name: eschar
def: "A skin and integumentary tissue symptom that is characterized by a scab formed especially after a burn." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=eschar]
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0019159
name: gastroenteritis
comment: doid/symp duplicate
is_a: SYMP:0000459 ! digestive system symptom

[Term]
id: SYMP:0019160
name: boil
def: "A skin and integumentary tissue symptom that is characterized by a localized swelling and inflammation of the skin resulting from usually bacterial infection of a hair follicle and adjacent tissue, having a hard central core, and forming pus." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=boil]
synonym: "furuncle" EXACT []
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0019161
name: muscle pain
alt_id: SYMP:0000626
def: "A pain that is characterized by a pain in one or more muscles." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=myalgia]
synonym: "myalgia" EXACT []
is_a: SYMP:0000099 ! pain

[Term]
id: SYMP:0019162
name: muscle tightness
is_a: SYMP:0000183 ! muscle symptom

[Term]
id: SYMP:0019163
name: eye symptom
is_a: SYMP:0000387 ! head symptom

[Term]
id: SYMP:0019164
name: excessive tearing
comment: doid/symp duplicate
is_a: SYMP:0019163 ! eye symptom

[Term]
id: SYMP:0019165
name: light sensitivity
is_a: SYMP:0019163 ! eye symptom

[Term]
id: SYMP:0019166
name: obsolete ulcerations
synonym: "ulcer" EXACT []
synonym: "ulcers" EXACT []
is_obsolete: true

[Term]
id: SYMP:0019167
name: pustule
def: "A skin and integumentary tissue symptom that is characterized by a small circumscribed elevation of the skin containing pus and having an inflamed base." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=pustule]
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0019168
name: obsolete pneumonia
def: "A pneumonitis that is characterized by an inflammatory illness of the lung resulting from a variety of causes including infection with bacteria, viruses, fungi, or parasites, and chemical or physical injury to the lungs. Its cause may also be officially described as idiopathic, that is, unknown, when infectious causes have been excluded." [url:http\://en.wikipedia.org/wiki/Pneumonia]
comment: doid/symp duplicate - reviewed 10/2022 & determined to be a disease
is_obsolete: true

[Term]
id: SYMP:0019169
name: arthritis
def: "Arthritis is a musculoskeletal system symptom characterized as an inflammation of joints due to infectious, metabolic, or constitutional causes." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=arthritis]
comment: doid/symp duplicate
is_a: SYMP:0000891 ! musculoskeletal system symptom

[Term]
id: SYMP:0019170
name: obsolete osteomyelitis
is_obsolete: true

[Term]
id: SYMP:0019171
name: spondylitis
def: "A nervous system symptom that is characterized by an inflammation of the vertebrae." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=spondylitis]
comment: doid/symp duplicate
is_a: SYMP:0000480 ! nervous system symptom

[Term]
id: SYMP:0019172
name: ocular lesion
is_a: SYMP:0019163 ! eye symptom

[Term]
id: SYMP:0019173
name: meningitis
def: "A nervous system symptom that is characterized by an inflammation of the meninges and especially of the pia mater and the arachnoid." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=meningitis]
is_a: SYMP:0000480 ! nervous system symptom

[Term]
id: SYMP:0019174
name: chills
synonym: "rigors" EXACT []
is_a: SYMP:0000567 ! general symptom

[Term]
id: SYMP:0019175
name: sweaty
def: "A skin and integumentary tissue symptom that is characterized by the excretion of moisture in visible quantities through the opening of the sweat glands." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=sweat]
synonym: "perspire" EXACT []
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0019176
name: malaise
def: "A neurological and physiological symptom that is characterized by an indefinite feeling of debility or lack of health, often indicative of or accompanying the onset of an illness." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=malaise]
is_a: SYMP:0000410 ! neurological and physiological symptom

[Term]
id: SYMP:0019177
name: fatigue
def: "A neurological and physiological symptom that is characterized by a weariness or exhaustion from labor, exertion, or stress." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=fatigue]
is_a: SYMP:0000410 ! neurological and physiological symptom

[Term]
id: SYMP:0019178
name: necrotic lesion
def: "A skin and integumentary tissue symptom that is characterized by regions of cell death to living tissue in an organ, which has suffered damage through injury or disease, such as a wound, ulcer, abscess, or tumor." [url:https\://en.wikipedia.org/wiki/Lesion, url:https\://en.wikipedia.org/wiki/Necrosis]
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0019179
name: lightheadedness
def: "A  balance symptom that is characterized by a condition of being dizzy or on the verge of fainting, particularly when one arises to a standing position. Lightheadedness is a predictable consequence of any medication tending to lower blood pressure." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=light-headedness]
synonym: "light-headedness" EXACT []
is_a: SYMP:0020045 ! balance symptom

[Term]
id: SYMP:0019180
name: constipation
def: "Constipation is a feces and droppings symptom involving the abnormally delayed or infrequent passage of dry hardened feces. Constipation may be categorized into three subtypes: normal-transit, slow-transit, and pelvic floor dysfunction." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=constipation, url:https\://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170709/]
comment: doid/symp duplicate
is_a: SYMP:0000146 ! feces and droppings symptom

[Term]
id: SYMP:0019181
name: hoarseness
is_a: SYMP:0000385 ! throat symptom

[Term]
id: SYMP:0019182
name: behavioral symptom
def: "A nervous system symptom that is characterized by an involvement, or relation to, or emphasizes behavior." [url:http\://dictionary.cambridge.org/dictionary/english/behavioural]
is_a: SYMP:0000480 ! nervous system symptom

[Term]
id: SYMP:0019183
name: hyperactivity
def: "A behavioral symptom that is characterized by an increase in movement, impulsive actions, a shorter attention span, and being easily distracted." [url:https\://medlineplus.gov/ency/article/003256.htm]
is_a: SYMP:0019182 ! behavioral symptom

[Term]
id: SYMP:0019184
name: limited attention
def: "A behavioral symptom that is characterized by a restricted rate of information processing by the brain." [url:https\://www.ncbi.nlm.nih.gov/pubmed/15084813]
is_a: SYMP:0019182 ! behavioral symptom

[Term]
id: SYMP:0019185
name: communication difficulty
def: "A behavioral symptom that is characterized by speech, language and communication needs or communication disabilities." [url:http\://www.mhldcc.org.uk/contents/6-communication-difficulties/a-what-are-communication-difficulties.aspx]
is_a: SYMP:0019182 ! behavioral symptom

[Term]
id: SYMP:0019186
name: obsessive interests
def: "A behavioral symptom that is characterized by obsessive and highly-focused interests." [url:http\://www.autism.org.uk/about/behaviour/obsessions-repetitive-routines.aspx, url:https\://en.wikipedia.org/wiki/Perseveration]
is_a: SYMP:0019182 ! behavioral symptom

[Term]
id: SYMP:0019187
name: repetitive behavior
def: "A behavioral symptom that is characterized by an unusual repetitive motor movements or manipulation of objects." [url:http\://www.autism.org.uk/about/behaviour/obsessions-repetitive-routines.aspx##repetitive]
synonym: "stimming" EXACT []
is_a: SYMP:0019182 ! behavioral symptom

[Term]
id: SYMP:0019188
name: intracranial hemorrhage
def: "A hemorrhage that is characterized by any bleeding occurring within the skull." [url:https\://www.ncbi.nlm.nih.gov/books/NBK542273/]
is_a: SYMP:0000041 ! hemorrhage

[Term]
id: SYMP:0019189
name: intracerebral hemorrhage
def: "A hemorrhage that is characterized by bleeding within the brain tissue itself." [url:https\://mayfieldclinic.com/pe-ich.htm]
is_a: SYMP:0000041 ! hemorrhage

[Term]
id: SYMP:0019190
name: subdural hemorrhage
def: "A hemorrhage that is characterized by bleeding that occurs within the skull of head but outside the actual brain tissue." [url:https\://my.clevelandclinic.org/health/diseases/21183-subdural-hematoma]
synonym: "subdural hematoma" EXACT []
is_a: SYMP:0000041 ! hemorrhage

[Term]
id: SYMP:0020000
name: airway stenosis
def: "A respiratory system and chest symptom that is characterized by a narrowing in the airway that obstructs the passage of air into the lungs.  Examples include tracheal and laryngotracheal stenosis." [url:https\://throatdisorder.com/breathing-disorders/tracheal-stenosis/, url:https\://www.ncbi.nlm.nih.gov/books/NBK554561/]
is_a: SYMP:0000514 ! respiratory system and chest symptom

[Term]
id: SYMP:0020001
name: apthous ulcer
def: "A skin ulcer that is characterized by a small recurrent, painful, round or ovoid ulcers with well-defined erythematous margins, like a halo, and a central yellow or gray floor found in the soft tissue of the oral cavity." [url:https\://en.wikipedia.org/wiki/Aphthous_stomatitis]
synonym: "aphthous stomatitis" EXACT []
synonym: "canker sore" EXACT []
is_a: SYMP:0000136 ! skin ulcer

[Term]
id: SYMP:0020002
name: anal abscess
is_a: SYMP:0000672 ! abscess

[Term]
id: SYMP:0020003
name: acholic stool
synonym: "clay-colored bowel movement" EXACT []
is_a: SYMP:0000146 ! feces and droppings symptom

[Term]
id: SYMP:0020004
name: ageusia
def: "A disturbances of sensation of smell and taste that is characterized by a complete loss of taste function of the tongue." [url:https\://www.ncbi.nlm.nih.gov/books/NBK549775/]
synonym: "loss of taste" EXACT []
is_a: SYMP:0000551 ! disturbances of sensation of smell and taste

[Term]
id: SYMP:0020005
name: acquired color vision deficiency
is_a: SYMP:0000320 ! vision symptom

[Term]
id: SYMP:0020006
name: agitation
def: "A neurological and physiological symptom that is characterized by a feeling of irritability or severe restlessness." [url:https\://www.ncbi.nlm.nih.gov/books/NBK493153/]
is_a: SYMP:0000410 ! neurological and physiological symptom

[Term]
id: SYMP:0020007
name: anterior scleral inflammation
is_a: SYMP:0019163 ! eye symptom

[Term]
id: SYMP:0020008
name: barking croup cough
def: "A cough that is characterized by a tight, low-pitched, and barky (like a barking seal) cough." [url:https\://www.seattlechildrens.org/conditions/a-z/croup/]
is_a: SYMP:0000614 ! cough

[Term]
id: SYMP:0020009
name: blind spot
is_a: SYMP:0000320 ! vision symptom

[Term]
id: SYMP:0020010
name: blurred vision with haloes
is_a: SYMP:0000012 ! blurred vision

[Term]
id: SYMP:0020011
name: bloody diarrhea
is_a: SYMP:0000570 ! diarrhea

[Term]
id: SYMP:0020012
name: weight symptom
is_a: SYMP:0000473 ! nutrition, metabolism, and development symptom

[Term]
id: SYMP:0020013
name: abnormal weight loss
def: "A weight loss that is characterized as deviating from what is normal or usual, typically in a way that is undesirable or worrying." [url:https\://www.merriam-webster.com/dictionary/abnormal]
is_a: SYMP:0000178 ! weight loss

[Term]
id: SYMP:0020014
name: chronic weight loss
def: "A weight loss that is characterized by conditions that last 1 year or more and require ongoing medical attention, or limit activities of daily living, or both." [url:https\://www.cdc.gov/chronicdisease/about/index.htm#]
is_a: SYMP:0000178 ! weight loss

[Term]
id: SYMP:0020015
name: obsolete gain of weight
comment: false
synonym: "weight gain" EXACT []
is_obsolete: true
replaced_by: SYMP:0000403

[Term]
id: SYMP:0020016
name: acute weight gain
def: "A weight gain that is characterized by a severe and sudden onset." [url:https\://medlineplus.gov/ency/imagepages/18126.htm]
is_a: SYMP:0000403 ! weight gain

[Term]
id: SYMP:0020017
name: chronic weight gain
def: "A weight gain that is characterized by conditions that last 1 year or more and require ongoing medical attention, or limit activities of daily living, or both." [url:https\://www.cdc.gov/chronicdisease/about/index.htm#]
is_a: SYMP:0000403 ! weight gain

[Term]
id: SYMP:0020018
name: overweight
def: "A weight symptom that is characterized by being too heavy for one’s height. Excess body weight can come from fat, muscle, bone, and/or water retention. Being overweight does not always mean being obese." [url:https\://www.cancer.gov/publications/dictionaries/cancer-terms/def/overweight]
synonym: "obesity" EXACT []
is_a: SYMP:0020012 ! weight symptom

[Term]
id: SYMP:0020019
name: postnasal drainage
def: "A nose symptom that is characterized by an an excessive secretion of mucous down the back of the throat." []
is_a: SYMP:0000388 ! nose symptom

[Term]
id: SYMP:0020020
name: abnormal scar formation
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0020021
name: abnormal wound healing
is_a: SYMP:0000092 ! skin lesion

[Term]
id: SYMP:0020022
name: bone conduction hyperacusis
def: "An ear symptom - need proper definition - placeholder for xref." [url:https\://hearinghealthfoundation.org/blogs/deciphering-a-mechanism-behind-bone-conduction-hyperacusis#\:~\:text=An%20example%20is%20bone%20conduction\,canals%20in%20the%20inner%20ear.]
is_a: SYMP:0000392 ! ear symptom

[Term]
id: SYMP:0020023
name: bone pain
is_a: SYMP:0000099 ! pain

[Term]
id: SYMP:0020024
name: bronchospasm
def: "A respiratory system and chest symptom that is characterized by constriction of the air passages of the lung (as in asthma) by spasmodic contraction of the bronchial muscles." [url:https\://www.merriam-webster.com/dictionary/bronchospasm]
is_a: SYMP:0000514 ! respiratory system and chest symptom

[Term]
id: SYMP:0020025
name: caseation
def: "A respiratory system and chest symptom that is characterized by necrosis of tissue with conversion of damaged tissue into a soft cheesy substance." [url:https\://www.merriam-webster.com/dictionary/caseation]
is_a: SYMP:0000514 ! respiratory system and chest symptom

[Term]
id: SYMP:0020026
name: chronic inflammation
is_a: SYMP:0000061 ! inflammation

[Term]
id: SYMP:0020027
name: wet cough
def: "A cough that is characterized by a production and expectoration (bringing up) of mucus (phlegm) or sputum." [url:https\://www.webmd.com/lung/productive-cough-causes]
synonym: "productive cough" EXACT []
is_a: SYMP:0000614 ! cough

[Term]
id: SYMP:0020028
name: poor wound healing
is_a: SYMP:0000092 ! skin lesion

[Term]
id: SYMP:0020029
name: concentration difficulty
def: "An alteration of consciousness that is characterized by a decreased ability to focus one's thoughts on something. Concentration difficulties can be related to difficulty staying awake, impulsiveness, intrusive thoughts or concerns, overactivity, or inattention. They can be caused by medical, cognitive or psychological problems, or, may be related to sleep disorders, medications, alcohol, or drugs." [url:https\://www.healthgrades.com/right-care/symptoms-and-conditions/concentration-difficulty]
is_a: SYMP:0000482 ! alteration of consciousness

[Term]
id: SYMP:0020030
name: patches of hair loss with a black dot pattern
def: "A hair symptom that is characterized by patchy hair loss and the presence of comedo-like cadaver hairs, which appear as black dots." [url:https\://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148295/]
is_a: SYMP:0000440 ! hair loss

[Term]
id: SYMP:0020031
name: chest discomfort
def: "A respiratory system and chest symptom that is characterized by pain, pressure, tightness, or other discomfort originating in or radiating to the chest, which constitutes an important indicator of potentially serious cardiac or cardiovascular disorders." [url:https\://www.ncbi.nlm.nih.gov/books/NBK416/]
is_a: SYMP:0000514 ! respiratory system and chest symptom

[Term]
id: SYMP:0020032
name: chest tightness
def: "A chest discomfort that is characterized by any type of pain or discomfort between your upper belly and lower neck." []
is_a: SYMP:0020031 ! chest discomfort

[Term]
id: SYMP:0020033
name: paroxysmal cough
def: "A cough that is characterized by a persistent cough with sudden onset due to difficulty expelling thick mucus from the tracheobronchial tree. This type of cough is associated with diseases such as Pertussis (Whooping Cough)." []
is_a: SYMP:0000614 ! cough

[Term]
id: SYMP:0020034
name: conjunctiva symptom
is_a: SYMP:0019163 ! eye symptom

[Term]
id: SYMP:0020035
name: conjunctival congestion
def: "An eye symptom that is characterized by (need def conjunctival congestion - placeholder for xref)." [url:https\://pubmed.ncbi.nlm.nih.gov/32283878/]
is_a: SYMP:0020034 ! conjunctiva symptom

[Term]
id: SYMP:0020036
name: conjunctival degeneration
is_a: SYMP:0020034 ! conjunctiva symptom

[Term]
id: SYMP:0020037
name: conjunctival suffusion
def: "An eye symptom that is characterized by (need def conjunctival suffusion - placeholder for xref)." [url:https\://en.wikipedia.org/wiki/Conjunctival_suffusion]
is_a: SYMP:0020034 ! conjunctiva symptom

[Term]
id: SYMP:0020038
name: conjunctival swelling
is_a: SYMP:0020034 ! conjunctiva symptom

[Term]
id: SYMP:0020039
name: contracture
def: "A musculoskeletal system symptom that is characterized by a permanent tightening of the muscles, tendons, skin, and nearby tissues that causes the joints to shorten and become very stiff." [url:https\://www.cancer.gov/publications/dictionaries/cancer-terms/def/contracture]
is_a: SYMP:0000891 ! musculoskeletal system symptom

[Term]
id: SYMP:0020040
name: hair symptom
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0020041
name: corkscrew hair
def: "A hair symptom that is characterized by coiled “corkscrew” hairs on the surface of the arms, legs and chest, which can occur as a result low level of ascorbic acid (vitamin C)." [url:https\://medlineplus.gov/ency/imagepages/2345.htm, url:https\://www.ccjm.org/content/ccjom/82/4/216.full.pdf, url:https\://www.miningjournal.net/life/tuesday-health/2021/09/urology-pearls-the-mystery-of-the-corkscrew-hair-part-2/]
is_a: SYMP:0020040 ! hair symptom

[Term]
id: SYMP:0020042
name: corneal scarring
def: "A cornea symptom that is characterized by scarring (an opacity or irregularity in the cornea) of the cornea, from trauma; abrasion; bacterial, fungal, viral, or parasitic infection; or disease, and can result in impaired vision, or even blindness." [url:https\://drstuartterry.com/eye-conditions/corneal-scarring/, url:https\://www.neohioeyes.com/cornea-center/corneal-scar/]
is_a: SYMP:0000239 ! cornea symptom

[Term]
id: SYMP:0020043
name: dark urine
def: "A urinary system symptom that is characterized by an elevation in the concentration of the the pigments from foods, dyes, and medications in urine. The dilution of these pigment is dependent on the amount of water intake and severe dehydration can lead to a dark color." [url:https\://www.mayoclinic.org/diseases-conditions/urine-color/symptoms-causes/syc-20367333]
is_a: SYMP:0000486 ! urinary system symptom

[Term]
id: SYMP:0020044
name: hair shedding
def: "A hair symptom that is characterized by significant falling out of hair, which may be a result of stress, high fever, and other factors." [url:https\://www.aad.org/public/diseases/hair-loss/insider/shedding]
is_a: SYMP:0020040 ! hair symptom

[Term]
id: SYMP:0020045
name: balance symptom
def: "A neurological and physiological symptom that is characterized by any of the following: dizziness or vertigo (a spinning sensation); falling or feeling as if you are going to fall; staggering when walking; lightheadedness, faintness, or a floating sensation; and confusion or disorientation." [url:https\://www.nidcd.nih.gov/health/balance-disorders]
is_a: SYMP:0000410 ! neurological and physiological symptom

[Term]
id: SYMP:0020046
name: feeding problem
def: "A feeding difficulties and mismanagement that is characterized by delays and/or disorders in the development of eating and drinking skills including disordered placement of food in the mouth, difficulty in appropriately manipulating food when it is in the mouth, difficulty chewing, and/or difficulty swallowing." [url:https\://link.springer.com/referenceworkentry/10.1007/978-1-4419-1698-3_1666]
is_a: SYMP:0000522 ! feeding difficulties and mismanagement

[Term]
id: SYMP:0020047
name: descending muscle paralysis
def: "A paralysis that is characterized by a loss of motor function in one or more muscles, which can also be accompanied by a loss of feeling (sensory loss). Descending paralysis contrasts with ascending paralysis in that descending paralysis presents in the upper limbs before the lower limbs. Descending paralysis occurs in conditions such as botulism." [url:https\://en.wikipedia.org/wiki/Paralysis]
is_a: SYMP:0000030 ! paralysis

[Term]
id: SYMP:0020048
name: skin peeling
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0020049
name: delayed psychomotor development
def: "A nutrition, metabolism, and development symptom that is characterized by the delay in development child's cognitive, emotional, motor, and social capacities from the beginning of life throughout fetal and neonatal periods, infancy, childhood, and adolescence." [url:https\://pubmed.ncbi.nlm.nih.gov/23622146/, url:https\://www.webmd.com/parenting/baby/recognizing-developmental-delays-birth-age-2]
is_a: SYMP:0000473 ! nutrition, metabolism, and development symptom

[Term]
id: SYMP:0020050
name: decreased tearing
def: "An eye symptom that is characterized by a reduction in the saline fluid secreted by the lacrimal gland." [url:https\://www.merriam-webster.com/dictionary/tear]
is_a: SYMP:0019163 ! eye symptom

[Term]
id: SYMP:0020051
name: decreased metabolism
def: "A nutrition, metabolism, and development symptom that is characterized by a reduction in the chemical reactions catalyzed by enzymes, which keep us alive. Metabolism allows organisms to grow, reproduce, maintain their structures, and respond to their environments and can be divided into catabolism (breaking down of organic matter) and anabolism (building of molecules)." [url:https\://simple.wikipedia.org/wiki/Metabolism]
is_a: SYMP:0000473 ! nutrition, metabolism, and development symptom

[Term]
id: SYMP:0020052
name: hand weakness
def: "A muscle weakness that is characterized by a reduction in muscle strength, which may be the result of a variety of conditions, such as carpal tunnel syndrome, arthritis, peripheral neuropathy, tendon damage, and ganglion cysts." [url:https\://www.buoyhealth.com/learn/hand-weakness, url:https\://www.medicalnewstoday.com/articles/hand-weakness]
is_a: SYMP:0000094 ! muscle weakness

[Term]
id: SYMP:0020053
name: mammary gland inflammation
def: "A skin and integumentary tissue symptom that is characterized by an inflammation of the mammary gland or udder and usually caused by infection." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=mastitis]
synonym: "inflammation of mammary breast" EXACT []
synonym: "mammitis" EXACT []
is_a: SYMP:0000488 ! skin and integumentary tissue symptom

[Term]
id: SYMP:0020054
name: severe mammary gland inflammation
def: "A mammary gland inflammation that is characterized by an increased intensity or severity of the condition." [url:https\://medical-dictionary.thefreedictionary.com/severe]
is_a: SYMP:0020053 ! mammary gland inflammation

[Term]
id: SYMP:0020055
name: pharynx inflammation
is_a: SYMP:0000385 ! throat symptom

[Term]
id: SYMP:0020056
name: cerebrovascular accident
def: "A nervous system symptom that is characterized by a loss of blood flow to part of the brain, which damages brain tissue. Cerebrovascular accidents are caused by blood clots and broken blood vessels in the brain." [url:https\://www.healthline.com/health/cerebrovascular-accident]
synonym: "apoplexy" EXACT []
synonym: "cerebral accident" EXACT []
synonym: "cerebral hemorrhage" EXACT []
is_a: SYMP:0000480 ! nervous system symptom

[Term]
id: SYMP:0020057
name: bronchiole inflammation
def: "A respiratory system and chest symptom that is characterized by acute inflammation of the bronchi, accompanied by inflamed patches in the nearby lobules of the lungs." [url:https\://en.wikipedia.org/wiki/Bronchopneumonia]
is_a: SYMP:0000514 ! respiratory system and chest symptom

[Term]
id: SYMP:0020058
name: severe bronchiole inflammation
is_a: SYMP:0020057 ! bronchiole inflammation

[Term]
id: SYMP:0020059
name: suppurative bronchiole inflammation
is_a: SYMP:0020057 ! bronchiole inflammation

[Term]
id: SYMP:0020060
name: low white blood cell count
is_a: SYMP:0019139 ! hemic system symptom

[Term]
id: SYMP:0020061
name: outlet dysfunction constipation
def: "A constipation that is characterized by difficulty passing bowel movements after they reach the rectum. One experiences difficulty evacuating the stool and often has to strain or press the fingers into the vagina or in front of or into the rectum to help remove the stool. Outlet dysfunction can be caused by inappropriate or abnormal muscle contraction of the pelvic floor (called pelvic floor dyssynergia or dyssynergic defecation) which can respond to biofeedback. It may also be due to a rectocele or other structural changes in the pelvic floor that will require medical or at times, surgical treatment." [url:https\://www.med.unc.edu/ibs/wp-content/uploads/sites/450/2017/10/Constipation.pdf]
xref: ICD10CM:K59.02
xref: ICD9CM:564.02
xref: UMLS_CUI:C0949134
is_a: SYMP:0019180 ! constipation

[Term]
id: SYMP:0020062
name: soft tissue necrosis
def: "A musculoskeletal system symptom that is characterized by necrosis (i.e. tissue death) of soft tissue, including muscle, fat, blood vessels, nerves, tendons, and tissues that surround the bones and joints." [url:https\://medlineplus.gov/ency/article/001443.htm, url:https\://www.health.ny.gov/statistics/cancer/registry/abouts/soft_tissue.htm]
is_a: SYMP:0000891 ! musculoskeletal system symptom

[Term]
id: SYMP:0020063
name: blood pressure
is_a: SYMP:0000567 ! general symptom

[Term]
id: SYMP:0020064
name: high blood pressure
is_a: SYMP:0020063 ! blood pressure

[Typedef]
id: part_of
name: part_of